LOCUS       DAVHSI010000001        86311 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.001, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000001 DAVHSI010000000
VERSION     DAVHSI010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 86311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.001"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..138
                     /locus_tag="VVR21_000001"
     CDS             <1..138
                     /locus_tag="VVR21_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6053977.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
     gene            complement(618..767)
                     /gene="rpmG"
                     /locus_tag="VVR21_000002"
     CDS             complement(618..767)
                     /gene="rpmG"
                     /locus_tag="VVR21_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6053978.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(783..965)
                     /gene="rpmF"
                     /locus_tag="VVR21_000003"
     CDS             complement(783..965)
                     /gene="rpmF"
                     /locus_tag="VVR21_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU6053979.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1117..1317)
                     /locus_tag="VVR21_000004"
     CDS             complement(1117..1317)
                     /locus_tag="VVR21_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6053980.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1320..2327)
                     /locus_tag="VVR21_000005"
     CDS             complement(1320..2327)
                     /locus_tag="VVR21_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6053981.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2519..4549
                     /locus_tag="VVR21_000006"
     CDS             2519..4549
                     /locus_tag="VVR21_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU6053982.1"
                     /translation="MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4553..4837
                     /locus_tag="VVR21_000007"
     CDS             4553..4837
                     /locus_tag="VVR21_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6053983.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4850..6196
                     /locus_tag="VVR21_000008"
     CDS             4850..6196
                     /locus_tag="VVR21_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6053984.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            6200..7057
                     /locus_tag="VVR21_000009"
     CDS             6200..7057
                     /locus_tag="VVR21_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6053985.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNKNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            7054..7986
                     /locus_tag="VVR21_000010"
     CDS             7054..7986
                     /locus_tag="VVR21_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU6053986.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8219..9922
                     /gene="ilvD"
                     /locus_tag="VVR21_000011"
     CDS             8219..9922
                     /gene="ilvD"
                     /locus_tag="VVR21_000011"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU6053987.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10083..10163)
                     /locus_tag="VVR21_000012"
                     /pseudo
     CDS             complement(10083..10163)
                     /locus_tag="VVR21_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10221..10562)
                     /locus_tag="VVR21_000013"
     CDS             complement(10221..10562)
                     /locus_tag="VVR21_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6053988.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10686..11537
                     /gene="rgg"
                     /locus_tag="VVR21_000014"
     CDS             10686..11537
                     /gene="rgg"
                     /locus_tag="VVR21_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU6053989.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SFPFLSVSLFTRYVREMVHKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKGNETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11728..12957
                     /locus_tag="VVR21_000015"
     CDS             11728..12957
                     /locus_tag="VVR21_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU6053990.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAENDLMEAYSFSQFITYISAIGGQAFGVW
                     LLGLSVNNFSLVAGINACFFLVSAVILFLGKSKLSLSMSSADGEKLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFFDNS"
     gene            13000..13191
                     /locus_tag="VVR21_000016"
     CDS             13000..13191
                     /locus_tag="VVR21_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6053991.1"
                     /translation="MDKENLSYVGKNLLLVVIVLLIAALVFVLGLVLGYGVIGDGDNV
                     FAVLSPAKWQELIGKFTGK"
     gene            13221..13766
                     /locus_tag="VVR21_000017"
                     /pseudo
     CDS             13221..13766
                     /locus_tag="VVR21_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735752.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
     gene            13872..14156
                     /locus_tag="VVR21_000018"
                     /pseudo
     CDS             13872..14156
                     /locus_tag="VVR21_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735752.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease"
     gene            14343..15896
                     /locus_tag="VVR21_000019"
     CDS             14343..15896
                     /locus_tag="VVR21_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6053992.1"
                     /translation="MEKHVEQRVEDVTYNKAKLWQIILFAMNNSSTNIYLVAFTFVTY
                     LSTGVLGLAALFVSQLMGYIRIFDGFIDPTIGVIIDKTDTKFGKYRPILVLGNIITAS
                     SLFMMLGLSGVSENLRLPLFILVLIIHKIGYSLQQTITKAGQVALTNDPKQRPIFNIV
                     DGIATTVLMTGSQVVVSGTLVPKHGGFTPSFFQELFLGVVIISAILGILAIIGIWEKD
                     NKKYFGLGEKTQETKLKDYWKVIKGNKPLQVLSISAAFVKFVAQLFGDSVIGVMLYGI
                     IFGDYALSGKMSMLLILPGILVTVGAAQLARRKGLRFAYITALQLGIAGLVALAAMLF
                     SAKPGMLDLTNWNLYTIGFFVVYIIARYASGAPSGLVLTMGADITDYETSVSGRYLSG
                     MIGTIFSLTDSIASSFAPMVVGFVLAGIGFGKEYPTVETAFSTDLRMALIVLLTVIPA
                     AVLSVSLFLMKFYKLDREEMARIQEKIHVMKAAKDEERVRAIAKNVPLSDMDYVDVTQ
                     YKVEQYEDK"
     gene            15972..17000
                     /locus_tag="VVR21_000020"
     CDS             15972..17000
                     /locus_tag="VVR21_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU6053993.1"
                     /translation="MKKILAFGEVLLRLSPPHYQTLTQARSLECQFGGSELNVLASLA
                     QLGHSVELVTALPRNEVGKMAEHFLFARQIGQKYLIRKEGRLGLYYYQKGFSLRPSQV
                     TYDRDYSAFSLSREEDYDLEGIFEDVDWFHVSGITVALNPVIRQLAFRLMEMAKEQGI
                     KVSFDLNYRESLWSSFEEAREKLSPFVGLADICFGLEPIQLLNESGKDMKDELGLKRS
                     YENREILLSVVKALAETYSLQSIAFTQREMTYNNEYLLKAYLYQDGVLYETEKESIQV
                     LDRVGTGDAFTAGIILGYLQEKSPQEVVDLGMASFQFKHTIEGDVNVISQSDIDLLLK
                     KGSREIKR"
     gene            17015..18814
                     /gene="uidA"
                     /locus_tag="VVR21_000021"
     CDS             17015..18814
                     /gene="uidA"
                     /locus_tag="VVR21_000021"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEU6053994.1"
                     /translation="MLYPIQTKTRSVYSLNGIWAFKQGNNDVQSLLDTDEVMVVPSSF
                     NDIVVDKEKRRFVGDNWYELMVAIPAVSDDEELVVRFGSVTHQAMVYADGQLIGKHKG
                     GFTPFECLVPSELYGLDQFRLTVCANNELNYTTLPVGNYSEEVDENGQIVKTVKENFD
                     FFNYAGIQRNVHLYKRPKNRVDDIVIRTELNNELTQAVVHVEVATVGQYDSIRIHIFN
                     QEGQELGLLENGRIVIDNPRLWEVLDAYLYTAKVELFDGESLLDTYCEQFGLRSVAVE
                     NGQFFINGKPFYFKGFGKHEDTFINGRGFNEAANLMDLNLLKDIGANSFRTSHYPYSE
                     EMMRLADRLGIVVIDEVPAVGLFQLFNAALNLTGDSDEVKNTWEVMQTKDAHELVIDE
                     LIARDKNHPSVVMWVVANEPAGHEKGARAYFEPLIQRMRDRDPSNRPVTLVNIMTATP
                     DKDEVMDLVDVVCLNRYYGWYAAHGDLKMAEKGLRKELETWQELYPDKPILITEYGAD
                     TLPGLHSMWDIPYTEEFQVDYYDMNHRVFDSISNVVGEQVWNFADFETTVGLIRIQGN
                     HKGLFSRNRQPKQIVREIKKRWTAIPNYHYKRK"
     gene            18860..19576
                     /locus_tag="VVR21_000022"
     CDS             18860..19576
                     /locus_tag="VVR21_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEU6053995.1"
                     /translation="MAKPLVEKASERLLELILERGYEVGDKLPNEYELAQDLEVGRST
                     VREAVRSLATRNILEVRQGSGTYISSKKGVSEDPLGFSLVRDRVKLTTDLFEVRYLLE
                     PRIAERVAQFASDEDVAKLEEIVLAIEEAVAAGDTKHLELDVKFHCMLAEMSGNLAMT
                     SLMPVINQSIHLINENYSNRQMKSNSLQAHRNILMAIKQRHPVAAYDSMLAHIISVRQ
                     VVLSEWFDKDMTLHGLNDHK"
     gene            19699..20319
                     /gene="eda"
                     /locus_tag="VVR21_000023"
     CDS             19699..20319
                     /gene="eda"
                     /locus_tag="VVR21_000023"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU6053996.1"
                     /translation="MLRQLKENYFFAVIRGKDEQDAKEIARHAVLGGIRNIEITFSTP
                     NAATVIKELQEEFSDDSSVVIGAGTVMNLNLAQEAIGAGASFLVSPHFDKKIQELAQE
                     TGVLYFPGCATATEIVTASQAGCSIIKLFPGGVLGHGFIKDIHGPVPEVDLMPSGGVS
                     VDNVADWKKAGACAVGIGSALASRVQAEGYDSVTLIARSFVAALEG"
     gene            20321..21721
                     /gene="uxaC"
                     /locus_tag="VVR21_000024"
     CDS             20321..21721
                     /gene="uxaC"
                     /locus_tag="VVR21_000024"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEU6053997.1"
                     /translation="MSFNDKNFMLKNEPAKELYVKIAELPIYDFHCHLDPKEIFEDKV
                     YEDIVDLWLGGDHYKWRLMRANGISEEEITGFASKLDKFKAWARTLERAFGNPLYHWS
                     HLELRQVFGIEELLTEENAERLYHQLNTYLQEHQISPRKLIADARVAFIGTTDHPLDN
                     LEWHKRLAEDSPIDTVVAPTFRPDEAFIEHRNFNLFIKRLEEVTEVAVRDFASFVEAL
                     GQRVSYFAQHGCRASDISFTAITYEEATLEELNDILLARMVGKEVGQSGINKWQTAIF
                     RELCRMYKKHGFVTQVHFGALRNNHTGLFEKLGADVGVDSIGDQTCLTGNLNRLLDNL
                     VKENALPKMIWYNLNPGYNIALANTLANFQANEEGRRSQLQFGAGWWFNDTKLGMIDQ
                     MNAYAEQGMLANFVGMLTDSRSFLSYQRHDYFRRILATYVGQWIVDEEVPEDYDRLGQ
                     FVEAISYYNAKEFFEQ"
     gene            21735..22835
                     /locus_tag="VVR21_000025"
     CDS             21735..22835
                     /locus_tag="VVR21_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEU6053998.1"
                     /translation="MKMSFRWYGKKDPVTLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKQMVEEAGLEITVIESIPVHEDIKQGKPNRDELIENYKTSIRNVGAAGIPVVC
                     YNFMPVFDWTRSDLHHPLPDGSTSLAFLKSDLAGVDPVADDLNLPGWDSSYSKEEMKN
                     VIENYRQNISEEDLWANLEYFIKAIMPTAEEAGVKMAIHPDDPPYGIFGLPRIITGQE
                     AVERFLNLYDSEHNGITMCVGSYASDPKNDVLAMTEYALKRNRINFMHTRNVTAGAWG
                     FQETAHLSQSGDIDMNGVVKLLVDYDWQGALRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKTPDFGIKVKTVGNKEG"
     gene            22838..23677
                     /locus_tag="VVR21_000026"
     CDS             22838..23677
                     /locus_tag="VVR21_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU6053999.1"
                     /translation="MTRVIEFKDKVVVITGAGGVLCGYLAKEFAKAGAKVALLDLNEV
                     AAQVFVDEIESVGGVAKTYKSNVLSKENLEEVRQQVLADFGPVDILVNGAGGNNPKAT
                     TDNEFHEIGLPVDTKTFFDLDEAGINFVFNLNYLGTLLPTQVFAQDMIGRSGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFFLTNQNRGLLF
                     DESGQPTARANKILTNTPMGRFGEAEELVGGVFFLADENLASFVNGVVLPIDGGFSAY
                     SGV"
     gene            23680..24477
                     /locus_tag="VVR21_000027"
     CDS             23680..24477
                     /locus_tag="VVR21_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6054000.1"
                     /translation="MKTDYVFCVDSDGCAMDTMTYKHKLFFGPLAADVFGVQDREAFL
                     TEWNRVNLYSRTRGINRFVGLVKGLEFAGVTGIEQLKNWVATTDSLSNASLEKLIAEQ
                     PSKDLELALEWSKQVNQAIKNYTGPVLAFIGVHKGLEKLSQLGKVYVVSSANKEAVDE
                     EWSEQGLLDFVTELYCQDRGKKEDVIKLLIDKGYNPDNIIMIGDSPGDLKAAELNNVH
                     FYPILVGREMRSWADLTETIADDFVNQTFAGEKETNLIQAFWKNLDD"
     gene            24524..26314
                     /locus_tag="VVR21_000028"
     CDS             24524..26314
                     /locus_tag="VVR21_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEU6054001.1"
                     /translation="MTHLVDLRKKPYNLDEEAISWVENTIAQMTLDEKIGHLFVNMGI
                     QRTEKYLTGVLEDYKIAAVRYNPGPAADIWEQNYILQTKSKIPLLIAANTESGGNGAV
                     TDGTKIGDEIKIAATADSRHAYEMGKVAGIEAAAVGCNASFAPIMDLSRNWRNPIIAN
                     RTWGADVDQVIELSKEYMRGIMEHGIVPFAKHFPGDGIDERDHHLSFASNPMTKSEWM
                     ETFGRIYGEMADAGLPGIMAGHIHLPNVEKEMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMIGMTASMPRRELLPTAIEAGCDLFLFFNDPEEDLQWMKEGLKNG
                     LLTEERLHDALRRTLGLKAKLGLHLFEGRRQEIMLPKEEALALIGKDEAKNLAKEVAD
                     KAITLVKSKQEGIFPVNPDRYKRILLVEVDGYKGGFGAMINAGKKRAADTLKELLEAR
                     GHEVSIWENTEARIAKLPEEERPAAIANVYASKRPIAEITDNYDLIINLVDVNSGGTT
                     QRIIWPAAKGTPDQPFYVHEIPTIVVSVQHPFALADMPQVATYINAYDGLPVTLETLV
                     TKLAGESSFTGVSPVDAYCGLVDTHIWRGN"
     gene            26325..28049
                     /locus_tag="VVR21_000029"
     CDS             26325..28049
                     /locus_tag="VVR21_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="HEU6054002.1"
                     /translation="MPRLVDLRKKPYYLNDDQIVWVESTLENLTDEEKIGQLFVNLFF
                     FGGDAFSGNNLSNQELINRYHIGGARYMNGSPEQVQGLINDLQSYSKVPLLVAANCDS
                     GGDGAVKGGTYISSGAQSEASRDSRIPYLAGLVSAREETALGVNVNFDPCVDIVQNWR
                     NTIVNTRAYGTNADDVIAYTSAYLEGLTAERDVIQCIKHFPGDGTEERDQHLVLGVNE
                     LSPEEWDDSFGRVYHHHIEAGVEMVMAGHIALLYYQQKLNPSLKDEDILPATLAPELI
                     QDLLKEKLEFNGLVITDASHMLGMTAAMRREDYVPAAIAAGCDMFLFFNNLEEDFEFM
                     LNGYRNGVITKERLHDALRRILGLKAKLNLHVKQAEGTLLKSADELAIIGCEEHLAWQ
                     REAADKAITLLKDTQHNLPISPETHRRIRLYYLEGEKEGIMAASTEVVDNLKSALEAR
                     GYEVTVNDGTTRIKGKTLQYREEVDLALTVANVIGYGAQNNYRIQWKTAMSNEVPWYV
                     HEVSTIFVSLNYTTHLHDVTMVKTAINAYHHNKNTIESLLDKLEGKDEFYGIPNENVW
                     ANKWQAKL"
     gene            28343..28489
                     /gene="pheS"
                     /locus_tag="VVR21_000030"
                     /pseudo
     CDS             28343..28489
                     /gene="pheS"
                     /locus_tag="VVR21_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646750.1"
                     /note="catalyzes a two-step reaction, first charging a
                     phenylalanine molecule by linking its carboxyl group to
                     the alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; forms a heterotetramer of
                     alpha(2)beta(2); binds two magnesium ions per tetramer;
                     type 1 subfamily; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
     gene            28655..30001
                     /locus_tag="VVR21_000031"
                     /pseudo
     CDS             28655..30001
                     /locus_tag="VVR21_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            30274..31563
                     /locus_tag="VVR21_000032"
     CDS             30274..31563
                     /locus_tag="VVR21_000032"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU6054003.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            31554..31634
                     /locus_tag="VVR21_000033"
                     /pseudo
     CDS             31554..31634
                     /locus_tag="VVR21_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            31901..32215
                     /locus_tag="VVR21_000034"
     CDS             31901..32215
                     /locus_tag="VVR21_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054004.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            32225..32431
                     /locus_tag="VVR21_000035"
     CDS             32225..32431
                     /locus_tag="VVR21_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054005.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            32431..32628
                     /locus_tag="VVR21_000036"
     CDS             32431..32628
                     /locus_tag="VVR21_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054006.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            32631..33365
                     /locus_tag="VVR21_000037"
     CDS             32631..33365
                     /locus_tag="VVR21_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU6054007.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            33377..34018
                     /locus_tag="VVR21_000038"
     CDS             33377..34018
                     /locus_tag="VVR21_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6054008.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            34036..34266
                     /locus_tag="VVR21_000039"
     CDS             34036..34266
                     /locus_tag="VVR21_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054009.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKKSK"
     gene            34302..34382
                     /locus_tag="VVR21_000040"
                     /pseudo
     CDS             34302..34382
                     /locus_tag="VVR21_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            34618..36381
                     /gene="aspS"
                     /locus_tag="VVR21_000041"
     CDS             34618..36381
                     /gene="aspS"
                     /locus_tag="VVR21_000041"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU6054010.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRVKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            36359..37300
                     /locus_tag="VVR21_000042"
     CDS             36359..37300
                     /locus_tag="VVR21_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6054011.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSLFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(37510..37590)
                     /locus_tag="VVR21_000043"
                     /pseudo
     CDS             complement(37510..37590)
                     /locus_tag="VVR21_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(37726..38712)
                     /locus_tag="VVR21_000044"
     CDS             complement(37726..38712)
                     /locus_tag="VVR21_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6054012.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(38722..39522)
                     /locus_tag="VVR21_000045"
     CDS             complement(38722..39522)
                     /locus_tag="VVR21_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU6054013.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTENFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(39775..40617)
                     /locus_tag="VVR21_000046"
     CDS             complement(39775..40617)
                     /locus_tag="VVR21_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6054014.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(40619..41911)
                     /locus_tag="VVR21_000047"
     CDS             complement(40619..41911)
                     /locus_tag="VVR21_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6054015.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(42022..43293)
                     /locus_tag="VVR21_000048"
     CDS             complement(42022..43293)
                     /locus_tag="VVR21_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6054016.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKSADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            43843..45360
                     /gene="malQ"
                     /locus_tag="VVR21_000049"
     CDS             43843..45360
                     /gene="malQ"
                     /locus_tag="VVR21_000049"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU6054017.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     VLPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            45386..47644
                     /gene="glgP"
                     /locus_tag="VVR21_000050"
     CDS             45386..47644
                     /gene="glgP"
                     /locus_tag="VVR21_000050"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU6054018.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(48689..49261)
                     /locus_tag="VVR21_000051"
     CDS             complement(48689..49261)
                     /locus_tag="VVR21_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054019.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(49862..50710)
                     /locus_tag="VVR21_000052"
     CDS             complement(49862..50710)
                     /locus_tag="VVR21_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6054020.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            50862..51140
                     /locus_tag="VVR21_000053"
     CDS             50862..51140
                     /locus_tag="VVR21_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054021.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            51142..53205
                     /locus_tag="VVR21_000054"
     CDS             51142..53205
                     /locus_tag="VVR21_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6054022.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(53283..54539)
                     /locus_tag="VVR21_000055"
     CDS             complement(53283..54539)
                     /locus_tag="VVR21_000055"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU6054023.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            54681..57146
                     /locus_tag="VVR21_000056"
     CDS             54681..57146
                     /locus_tag="VVR21_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6054024.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPIQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGASATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            57211..58122
                     /locus_tag="VVR21_000057"
     CDS             57211..58122
                     /locus_tag="VVR21_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6054025.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSIVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIVLIILPMIFLSIEEAKESR"
     gene            58352..59050
                     /gene="dapD"
                     /locus_tag="VVR21_000058"
     CDS             58352..59050
                     /gene="dapD"
                     /locus_tag="VVR21_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU6054026.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            59118..60248
                     /locus_tag="VVR21_000059"
     CDS             59118..60248
                     /locus_tag="VVR21_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU6054027.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILAYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            60260..60799
                     /locus_tag="VVR21_000060"
     CDS             60260..60799
                     /locus_tag="VVR21_000060"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU6054028.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDVSKIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            60783..61460
                     /locus_tag="VVR21_000061"
     CDS             60783..61460
                     /locus_tag="VVR21_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU6054029.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGSAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(61532..62431)
                     /gene="galU"
                     /locus_tag="VVR21_000062"
     CDS             complement(61532..62431)
                     /gene="galU"
                     /locus_tag="VVR21_000062"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU6054030.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKNGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(62453..63469)
                     /locus_tag="VVR21_000063"
     CDS             complement(62453..63469)
                     /locus_tag="VVR21_000063"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6054031.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            63681..64062
                     /locus_tag="VVR21_000064"
                     /pseudo
     CDS             63681..64062
                     /locus_tag="VVR21_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(64236..64661)
                     /locus_tag="VVR21_000065"
     CDS             complement(64236..64661)
                     /locus_tag="VVR21_000065"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6054032.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYKARGQGKTCLTE"
     gene            complement(64729..65379)
                     /gene="phoU"
                     /locus_tag="VVR21_000066"
     CDS             complement(64729..65379)
                     /gene="phoU"
                     /locus_tag="VVR21_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6054033.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(65394..66146)
                     /gene="pstB"
                     /locus_tag="VVR21_000067"
     CDS             complement(65394..66146)
                     /gene="pstB"
                     /locus_tag="VVR21_000067"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6054034.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(66148..66963)
                     /gene="pstA"
                     /locus_tag="VVR21_000068"
     CDS             complement(66148..66963)
                     /gene="pstA"
                     /locus_tag="VVR21_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6054035.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(66956..67819)
                     /gene="pstC"
                     /locus_tag="VVR21_000069"
     CDS             complement(66956..67819)
                     /gene="pstC"
                     /locus_tag="VVR21_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6054036.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(67937..68812)
                     /locus_tag="VVR21_000070"
     CDS             complement(67937..68812)
                     /locus_tag="VVR21_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU6054037.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(68979..70310)
                     /locus_tag="VVR21_000071"
     CDS             complement(68979..70310)
                     /locus_tag="VVR21_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU6054038.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLSGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(70311..71018)
                     /locus_tag="VVR21_000072"
     CDS             complement(70311..71018)
                     /locus_tag="VVR21_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6054039.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(71102..71404)
                     /locus_tag="VVR21_000073"
     CDS             complement(71102..71404)
                     /locus_tag="VVR21_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU6054040.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(71391..71612)
                     /locus_tag="VVR21_000074"
     CDS             complement(71391..71612)
                     /locus_tag="VVR21_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU6054041.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            71574..72131
                     /locus_tag="VVR21_000075"
                     /pseudo
     CDS             71574..72131
                     /locus_tag="VVR21_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(72446..74137)
                     /locus_tag="VVR21_000076"
     CDS             complement(72446..74137)
                     /locus_tag="VVR21_000076"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU6054042.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            74273..74719
                     /gene="argR"
                     /locus_tag="VVR21_000077"
     CDS             74273..74719
                     /gene="argR"
                     /locus_tag="VVR21_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6054043.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            74770..77304
                     /gene="mutS"
                     /locus_tag="VVR21_000078"
     CDS             74770..77304
                     /gene="mutS"
                     /locus_tag="VVR21_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU6054044.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            77451..79145
                     /gene="patA"
                     /locus_tag="VVR21_000079"
     CDS             77451..79145
                     /gene="patA"
                     /locus_tag="VVR21_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU6054045.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEVIYSIGTWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILALQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(79475..79738)
                     /locus_tag="VVR21_000080"
                     /pseudo
     CDS             complement(79475..79738)
                     /locus_tag="VVR21_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            79936..81702
                     /gene="patB"
                     /locus_tag="VVR21_000081"
     CDS             79936..81702
                     /gene="patB"
                     /locus_tag="VVR21_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU6054046.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            81841..82530
                     /locus_tag="VVR21_000082"
     CDS             81841..82530
                     /locus_tag="VVR21_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6054047.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            82534..82713
                     /locus_tag="VVR21_000083"
     CDS             82534..82713
                     /locus_tag="VVR21_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054048.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            82700..84049
                     /locus_tag="VVR21_000084"
     CDS             82700..84049
                     /locus_tag="VVR21_000084"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU6054049.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLIKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            84173..85633
                     /locus_tag="VVR21_000085"
     CDS             84173..85633
                     /locus_tag="VVR21_000085"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU6054050.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            85647..86081
                     /locus_tag="VVR21_000086"
     CDS             85647..86081
                     /locus_tag="VVR21_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6054051.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVSELIPYWWGEERASKFNER"
     gene            86202..86273
                     /locus_tag="VVR21_000087"
     tRNA            86202..86273
                     /locus_tag="VVR21_000087"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:86235..86237,aa:Glu,seq:ttc)
BASE COUNT        25355 a        15875 c        18997 g        26084 t
ORIGIN      
        1 gaatcaggtt caatggctac tggttggttt acagtttctg gtaaatggta ctatacctat
       61 aattcaggag atttattagt aaacacgact acacccgatg gctatcgagt caatgctaac
      121 ggtgagtggg taggataggt atccattagc taaatctaat cattctgaac taaaaaatct
      181 tcttacatat gtaggaagat tttttggatt cttaaaacta gtttaaaaga ctacgctatt
      241 taaaccaatt ttaagaatgg atatataagg atattcagaa atctagttgg tcaacttttg
      301 tattttgaat ataccttaga tggtgacgat gtcttggtat atctggtact cacttacata
      361 ttctaactta ttttaactaa gatacaactg tagttggtga atttgctaca aatagtgtag
      421 aggcgttatt tgaaaaatat acaaaaaagg aaccccaact tacatttgag ttcctcttgc
      481 ttttaattgt ccgaatccgt attcttattt caaaaaaggt agtcattcga atgatttccc
      541 ttgcaatata gtgaaattaa caaaaagaaa aaacgctgat caagcgtttt tcttctgtat
      601 tgattcgtat tgaatgctta cttcacttct gtaaacacaa cgtgtttgcg aagttttggt
      661 gagtatttct tcaattgaag gcggtctgga gtgttacgtt tgtttttaga agtaaggtac
      721 aagcgttcac cagattcttt gtgttcaagt gtaatattta cgcgcatggt atctcccttc
      781 tattattcag ctgatgcagc tttagcgatt ttacgtcctt tgtagtatcc tttaagtgat
      841 acacggtgag aacgtgagta atctccagta gtttcgtcaa agtttacaga tggagctgtt
      901 actttgtagt gtgtacgacg tttgtttttc ttcgcttttg aagtgcgacg tgcaggtact
      961 gccattttga tttctccttt aggtatttat attcgattca atctactgat tttcatcaac
     1021 catattagga taacacattt tttttgtaaa gtaaagttac ttgacaaaaa aagatgaaaa
     1081 aattctccta tccgacacgg cagacaggag aaggtgttaa atatcaatct caaatggttc
     1141 gtcaatggtt tctgatacgt attttccgtc tttcttccgt tgcttgacac actctgtgag
     1201 gagatattcg atttgcccat tgactgaacg aaagtcgtct tctgcccatg atgcgagtgc
     1261 agcgtataac tttgttgaga gtcgaagggg gatctgcttt tttttagctt cagccatctt
     1321 tagtaaagac ttcctgtgtt gacaattggt tgtgcatcat gattgccaca aagaacgaca
     1381 aggagatttg aaaccatggc agcttttcgt tcttcgtcaa gttctaccaa ttccccttca
     1441 ttgagccgtt ctagtgccat ttcaaccatt cctacagcac catctacaat catcttccgt
     1501 gcatcaataa tggcagatgc ttgttggcgt tgaagcataa cggcagcaat ttctggagca
     1561 taagctaggt aagtgatacg tgcttcaagg atttccaagc cagcatcctc aacacgactt
     1621 tggatttctt cacgaatacg gttagcaaca atttcgctag agccacggag actaccttca
     1681 tctgcttgcc cgtcacccgt agtatccaca ttaggagaca catcgtaagg atagatgcgg
     1741 acaatattac ggagggcgct atcacattgc aatgaaagat attctttgta gttatcaacg
     1801 ttgaagactg ccttagcggt atcgacaact ctccaagtta ccgcgatacc gatttctaca
     1861 gggtttccta agcaatcatt gattttttga cgagaattgc tcaaggtcat gactttgagg
     1921 gaaatgtgtt tcttgccaat ttcaagattt acatcattgt catttgatga tttagcacct
     1981 aaaaaaggag attttgtgct aacatcacca ctttgtccaa gtcgagtgtg gtttgcaggg
     2041 ttgactgcta cgctgaaggg attgacaaag taaaaaccag gttctttgat ggtacctgta
     2101 taattaccaa agagtgtcag aaccagagct tcctgaggtt tgacaacttt taaaccagca
     2161 tgagctagac ctgcaattac gattagtaaa ggtccgataa taattccaaa aatgttttcc
     2221 gaaccaacac ccattataaa tataaagata ccaagtacga gcgtcaattc aatgagaatc
     2281 aatgcgaata caccatttgg ttttgaattg attagttttt cagtcataag aatgacctcc
     2341 cattatttga tatctaaatg atatcacttt gtttttaaaa gtcaatagaa agttgaaaaa
     2401 taatcactaa aaactttcag cccaataatt tcttttaaaa ggtgagatta tattgtgctc
     2461 aaatactctt ttattcttat aacttttaca ctataattgt agttagaaag gaagagaaat
     2521 gtttgattat agagcactag ttattttgat gactttgatg gatcattgtg aggtatcatt
     2581 atatgagtta tctgttaagg tgagcttacc tataaaggaa gtcaaagaag gaatagatta
     2641 tttagtgcct tatttagcta ataaagggat agtgctggat aaaaagcaag gtcgctatag
     2701 tttatcaaat cgtacgaagc agtctttgac agatattatt aagtcggatg aattggtttt
     2761 accaaagtcg actcgcttag ctttaatcta tctttacact ttttgccgat tagattttat
     2821 atcgaataat cattaccaag actttttgaa agtaagtaag aatacaacct tatctgatat
     2881 tcaatcatta agaaagatta tgttagataa tgatttggag ctagggtaca gtagagcaaa
     2941 aggttatact ttacacggtt cagagtggaa taagcaccgt ttagcttttc aaatggttag
     3001 tgagttgctg gaatcctcca tagggatttg gggtttggat tatgttttat ccagttgggg
     3061 gtattcatta acttatgatt tgattgatca ggtagttaaa gattattatg agaagctaca
     3121 gctagtacct attgttaatc aattaaaagt ttaccttttc ggtttagtat tcattctgtg
     3181 taggtatcaa agggatgttg aaagagtatg tctttcagag acattagtat ctcctgttat
     3241 tcaagatata acgactattt tattggatac agtggttgat ttgggaatta tagatacggt
     3301 gttttctgag gatgattatc gctatatcac cgttttatta tcaagttgct ttgaaggtga
     3361 agtagatgtt gctccggttt actttaatca attaacagag gctattataa gtagaatgga
     3421 agatatttct ttgttacatt ttaaacaaag ggaaggattg agagaaaatc ttcgccgcca
     3481 ccttataccg gcttactata gattaaagtt cggcctacct agttcaaatg aatatgtatt
     3541 gcatgttaaa gaacattatc ctgatttatt tgaattagtc aaagattctt tgatgccctt
     3601 gatggacgct attgacaatc ccatacctga tagtgaaaca gcatattttg ttatccattt
     3661 cggaggttat ttaaagaaag cagatacttt gcctcaaaaa tgctataaag cagcaatcat
     3721 ttgtcctaat ggtgttagtt cttcattgat gttaaaagag aatctattag cattatttcc
     3781 tcaaattgag tttataggaa cctcaaagat tgatgattta caggtgaaag ctagtagtga
     3841 ctatgatatg gttttttcta ccataaaggt ggagacagaa aagccaaatt atctagtttc
     3901 ggttatgatg actgaagagc aagcaataca actagtagaa ctagtgttaa aagattttcc
     3961 gaatttagag tatggggatt ttgagattga acaaatcctg aatattgtca aaagatatgg
     4021 aattattaca caagaattgg aattaagatt ggcgttaaag aattatcttt accaaaaaaa
     4081 tgatagaaag gaaattgtac cagtgctaga acaactcatt accaaagaaa cctatcaggt
     4141 tagttcgcaa aaattaggat ggaaggaggc gattcgttta gcagctaaac cgcttttgga
     4201 tcaagataag ataactgaga actaccctga ggcaatgatt caaaaagtag aagagtttgg
     4261 gccttttatt aatttaggga agggagtagc aattcctcac gctcggccag atgaaggtgt
     4321 gaatgaaata ggaatgtcaa tgttagtttt ggaagaaccg atttatttat tggataatcc
     4381 agaacaagag gtaagattgt tgatttgtat tgcagccatt gataatgaga gtcatttaaa
     4441 ggctttgtca catttaacaa caattttaag agataaaaat catgttcaaa ctttaatatc
     4501 atcaaaaaac tatgatgaca ttaaaatgat aattaaacag gaggattaga taatgttaaa
     4561 aattggtaca gcttgtggtt caggattagg ttcaagtttt atggtacaga tgaatattga
     4621 atctgtattg agtgatttga atgtttcgga tgtagaagtt gaacattatg atttaggtgg
     4681 agcagatcca aatgcagctg atatttggat tgttggtcgt gatctagctg attcagctag
     4741 tcatcttgga gatgttcgta tcttaaatag tattattgat atggatgaac tacgagaatt
     4801 aattactaaa ctttgtgaag aaaaaggact tatataggag gctagcgtta tgatgaagtt
     4861 catattggat attgttagta caccagctat tttagtagct ttaattgcaa ttttaggatt
     4921 agttcttcag aagaagaaat tacctgatat tattaaaggt ggaattaaga cctttgttgg
     4981 tttcttagtt gtatctggtg gtgcaggaat tgtacaaaat tctttaaatc catttggtac
     5041 catgtttgag catgcttttc atttatctgg cgttgtgccg aataatgaag caattgtagc
     5101 tgtagcttta acaacatatg gctcagctac tgcactgatt atgtttgcag gcatggtgtt
     5161 caatatctta atcgctcgtt ttactcgatt taaatatatt tttttaacag ggcaccacac
     5221 tctatatatg gcatgtatga ttgcggtcat tttatcagtt gctggcttta ctagcttgcc
     5281 tcttatctta ctaggaggat tagcactcgg tattattatg agtatttccc cagcatttgt
     5341 gcaaaaatat atggttcaat taactggaaa tgacaaggtg gctttaggtc atttcagttc
     5401 tttgggatat tggttgagtg gttttactgg tagccttatc ggtgacaaat caaaatcaac
     5461 agaggacatt aaatttccaa agagtttagc ttttttacgt gatagtactg ttagtatcac
     5521 tttatctatg gcagttattt acattattgt agctatcttt gcagggtcag aatatataga
     5581 aaaagaaatc agtagtggta caagtggtct agtttatgct ttacaattag caggtcaatt
     5641 tgcagcaggg gtatttgtta ttttagcagg tgttcgcctt attttgggcg aaattgttcc
     5701 agcctttaaa ggtatttcag agcgtcttgt acctaattca aaacctgctt tggattgtcc
     5761 gattgtttat acttatgcac ccaatgcagt tctaattgga tttatctcta gttttgttgg
     5821 tggtttagta agtatggcaa ttatgattgc ttcaggaacg gttgttatct taccaggcgt
     5881 tgtacctcat ttcttctgtg gagcgactgc aggtgtcatt gggaatgcat ctggtggtgt
     5941 tcgtggagcc actattggag catttttaca aggtatttta atcagttttc tcccagtctt
     6001 tttaatgcca gttttgggag gactcggttt ccaaggatca actttctcag atgcagattt
     6061 tggtctatca ggaattattt taggaatgtt aaatcaattt ggctcacaag caggcattgt
     6121 gattggtctt gttcttattt tagcagttat gtttggagta tcctttatta aaaagccatc
     6181 tgcaaaggag gaataaggga tgattttaag taaaaataga gaagatgagt taagaaaatt
     6241 tgcgactaac atccgattaa atactcttag aacattgaat catcttggat tcggacatta
     6301 cggaggaagt ttgtctatcg tagaagtttt agcagtgctt tatggtgaaa taatgccaat
     6361 gactccagaa atatttgcag cacgagatag agattatttc atattatcaa aaggtcatgg
     6421 aggaccagct ctatacagta cactctattt gaatggtttc tttgacaaag aattcttata
     6481 ttctttaaat aaaaatggaa ccaaattacc gtctcatcct gatagaaatc taacgccagg
     6541 catagatatg acaacgggct ctttaggaca aggaattagt gttgcaactg gacttgcata
     6601 tggtcagaga ataagaaaga gtccctttta tacttatgct attgttggag atggtgagtt
     6661 aaatgaggga caatgttggg aggctataca gtttgcttct catcaacagt tatccaactt
     6721 aattgtattt gttgatgata acaaaaaaca attagatggt tttacaaagg atatttgtaa
     6781 tccaggtgat ttcgtagaaa aattttcagc atttggattt gaatccatta gggtcaaggg
     6841 ttcagatatt agagaaattt atgaagggat tgtccaatta aaacagtcaa ataattcatc
     6901 acctaagtgc attgtattag atactattaa aggtcaaggg gttcaagagc tggaagaaat
     6961 gaaatccaac catcatcttc gccctactgt agaggagaga caaatgttaa cttcagttgt
     7021 agaaagatta agtcaggaat tggaggaaac agaatgatga gaagtacgaa agaattacgg
     7081 catgtatata gagacttcct tttagaggct aatcaaagtg attctgatat agtagtctta
     7141 gaagccgatt tgtcaagttc gatggctact cataatcttg aaaaggactt tggagaccgt
     7201 tatgtgaatg ttgggattat ggaagcagaa atggtcggcc ttgcagcagg cttgtctatt
     7261 caggggttta gaccttatct tcatacattt ggtccttttg cttcacgaag agtatttgat
     7321 caattattta tttctcttgg atacgcacaa ttggatgcca ctgtgattgg atcagatgca
     7381 ggagtaactg cagaaatgaa tggcgggaca catatgccat ttgaagaaat tggattgtta
     7441 cgtttaattc ctaaatcgat catttttgaa gcaactgatg atatccaatt tcgtgaaata
     7501 ttgaaccaga cattagactt aaaaggatta aaatatattc gaacaattag aaaagctcca
     7561 gttcctgtgt atcaaggtgg agaagatttt tctaaaggct acattgagtt aaggcatggt
     7621 gaagatcttg taatcgttgc ttctggtata atggttgctc caagtattcg agttgcagat
     7681 gaactgtcta aattaggtta ttcagtaggt gtgatagatt tatttagaat caaaccgata
     7741 ccagaacaga taaaaacaat gttaagtgga aaaactatat ttactgtaga aaaccacaat
     7801 cagataggtg gaattggcag tgctttatgt gaattattct ctgatgatgg aataacaaaa
     7861 attcatcgga tgggtgttca agaaagattt ggtcaagtag ggaaaatgga ttatcttctt
     7921 aatgagtatg gtttgagtga atcgaatata aaagagaagg ttctagaaat ttataatgca
     7981 agatagatgt taaatacact tatctgaaag aatttctgta aaaattacat tacgttattt
     8041 aaagaaagcg gattaaaaag catattctgg tcatcagaaa gtgcactaat ccgctttgtt
     8101 gtttttaatt ttaaatattt cacatgcgta tagaattttc tgaaaattca agaattttat
     8161 tctgttcatt gcctttaaat tgtgctataa tagtaaaaac tgaaatggga gggataagat
     8221 gactgaatta gataaacgtc accgcagtag catctatgac agcatggtta aatcacctaa
     8281 ccgtgctatg cttcgtgcga ctggtatgac agataaggac tttgaaacat cgattgtggg
     8341 agtgatttcg acttgggcgg aaaatacacc atgtaacatt cacttgcatg atttcgggaa
     8401 actggctaaa gaaggtgtca aatctgcagg cgcttggcct gtacagtttg gaaccattac
     8461 cgtagcggac gggatcgcta tgggaacgcc tggtatgcgt ttctctctaa catctcgtga
     8521 catcatcgcg gactccatcg aggcggctat gagtggtcac aacgtggatg ccttcgtcgc
     8581 tatcggtggc tgtgacaaga acatgcctgg atctatgatt gctattgcta atatggatat
     8641 cccagctatt ttcgcctatg gtggaactat tgcaccggga aatcttgatg gtaaagatat
     8701 cgacttggtt tctgtctttg aaggtatcgg aaaatggaac cacggtgaca tgacagctga
     8761 ggacgtgaaa cgtcttgaat gtaatgcctg ccctggccct ggtggttgtg gtggtatgta
     8821 tactgctaat accatggcaa ctgctatcga agttctaggg atgagtttgc cagggtcatc
     8881 ctctcaccca gctgaatcag ctgataagaa agaagatatc gaagcagcag gacgtgctgt
     8941 tgttaagatg ttggaacttg gtctcaaacc atcagatatc ttgactcgtg aagcctttga
     9001 agatgctatc actgtaacga tggctctcgg tggttctaca aacgccactc ttcacttgct
     9061 cgccattgcc catgccgcaa atgttgactt gtcacttgag gacttcaata cgattcaaga
     9121 acgtgtgcct cacttggccg acttgaaacc atctggtcag tatgtcttcc aagacctcta
     9181 cgaagtcggt ggtgtccctg cggttatgaa gtacttgttg gcaaatggtt tccttcacgg
     9241 agatcgcatc acatgtactg gtaagactgt agctgaaaac ttggctgact ttgcagactt
     9301 gactccaggc caaaaagtta tcatgccact tgaaaatcca aaacgtgcgg atggtccgct
     9361 tatcatcttg aacgggaacc ttgctcctga cggtgcagtt gccaaggtat caggtgttaa
     9421 agtgcgtcgt cacgttgggc cagctaaggt ctttgactca gaagaagatg cgattcaggc
     9481 cgttctgaca gatgaaatcg ttgatggcga tgtagtcgtt gttcgttttg ttggacctaa
     9541 aggtggtcct ggtatgcctg agatgctgtc actttcatca atgattgttg gtaaaggtca
     9601 gggagataag gtggccctct tgacggacgg acgtttctct ggtggtactt atggtctggt
     9661 tgttggacat atcgctcctg aagctcagga tggtggacca attgcctatc tccgtaccgg
     9721 cgatatcgtt acggttgacc aagataccaa agaaatttcc atggccgtat ccgaagaaga
     9781 acttgaaaaa cgcaaggcag aaacaacctt gccaccactt tacagccgtg gtgtcctcgg
     9841 taaatatgcc cacatcgtat catctgcttc acgcggagcc gtgacagact tctggaatat
     9901 ggacaagtca ggtaaaaaat aaactcatac tcgaaaatct cttcaaatca cgtcaacgtc
     9961 gccttgccgt aggtatggtt actgacttcg tcagttctat ctacaacctc aaaacagtgt
    10021 tttgagctga cttcgtcagt tctatccaca acctcaaaac agtgttttga gctgacttcg
    10081 tcagttctat ccacaacttc aaaacagtgt tttgagcaac ctgcggctag ttttctagtt
    10141 tgccctttga ttttcattga gtatcaaaaa gcaagccatt ttcggcttgc ttttttcatc
    10201 tttaaaagtg attggcctgc ttaacgaggt ggtagtccaa gggcaatacg gccatagcga
    10261 ctgattcgtg tgattttcca agcaggcgac caggtaactt caaccttgat atctttgata
    10321 ccctcgattt gtttcagacc tgccacaatt tcaataggca ggctttcggc gcaatcacag
    10381 gcagtatcgg tgaaggtcat gacaatcttg cagagccccg tttcatccag attgatttca
    10441 taaatcagac ctagattgta aacatccaat tccacatctg tatcaaaaac tttctctagt
    10501 ttttcgataa tttggtcttg caaggccaaa gcacggtcat tgattttgat atcgtctctc
    10561 atagcagtcc ctccacgtga taaatatcct ctattttctc ataattctga caatttggca
    10621 agtttttgat gaattttctg aaaaatatga taaaatgaag aaaatacgga atcaagggga
    10681 agtctatgga gcagattgga aaagtcttta gacaattacg agagtcaaga aatatctcac
    10741 tgagacaagc aaccggagga caattttcgc cgtctatgtt gtcccgtttt gaaacaggtc
    10801 agagtgagct ttcggtggaa aagtttctat ttgctctgga aaatatatct gccagtgtgg
    10861 aggagatcct ctttctggcg agaggtttcc agtatgatac agattctgag ttgagaaaag
    10921 aaattacaga tgtcttggaa ccaaagaata tagcacctct tgaggactta tatcgcaggg
    10981 agtatcaaaa gcatgcccat tctcacaaca aacagaaaca tattctaaat gccattatta
    11041 tcaagtctta tatgaagagc atagatgaaa gggtagagtt aacagcagag gaaggaaaag
    11101 tccttcatga ttatttgttt tctaccgaga tctggggaat ctatgaactc aatttatttt
    11161 cagtcagttt tccattttta tctgtttctc tttttactag atatgtacga gaaatggtac
    11221 ataaatctga ttttctaatg gaaatgtctg gcaatcgaaa cctttttcat actatactat
    11281 tgaatggctt tttagctagt attgagtgtg aagaatttac caatgcctat tattttaaac
    11341 gtgttatcga agagcatttc tacaagggaa atgagaccta tttccgaatt gtttatctgt
    11401 gggcagaagg tctccttgat agcaagcaag gtagagtcaa ggaaggtcag aaaaagatgg
    11461 aggatgctgt ccgtattttt gagatgcttg gctgtaataa atctgccgaa tactatagaa
    11521 atacgaccga atgttgagta tctgcaaacc aagaaaaaat ttgaagcgat agaactgttg
    11581 ccctctctca ggtcattaca aaagttctat cgtttttttg ctcattttgt ttgttgcata
    11641 tattcaaaag aatcgtttcg caaattcata agtgctatac taaagctatt cttgatgtag
    11701 aacttagaac aagaagggag attatctatg aaactattgt ttagaaatcc agcttataga
    11761 attttgactt tatcacgctt cttcaatgct tttggtgctt cgattttcaa cctggtcttt
    11821 atcgtctatg catcgacctt gtcacaagca tcttttgctg ttgctatggc gaatattgtc
    11881 atgattcttc cgaccctctt tacagttttt gtagggattc gggcagatta cacgagggac
    11941 aaggtcaaat ggatggtcta tagcggtttg tttcaggcgg ttctattttt tctagcagcc
    12001 ctagttgttc agcaagctag tctctttgcc ttttctagcc tgtgtttgat caatgtcatt
    12061 agtgatatca tcagtgattt tgcaggtggc ctgcgcatgc ctcttattaa ggaaaaagta
    12121 gctgaaaatg atttgatgga ggcttattct ttttcccagt ttatcaccta tatttcagct
    12181 attggtggtc aagcttttgg agtctggctc ttaggtctat cggtcaacaa tttttccctc
    12241 gttgcgggaa tcaatgcctg tttcttccta gtatcagccg tcatcctctt tttaggaaaa
    12301 agcaaattga gcctgtcaat gtcatctgct gatggtgaaa aactaaaaaa tgagaagctt
    12361 tctatcaaag accagttcct aacaatttac cgaaatttac gtctcgtttt tcttaaaagt
    12421 ggacagaaaa actttggttt tatgctcttt gctgtcttgc ttattaattc cttgggtggc
    12481 gctttgggtg gaatttataa tatcttcttt ttgagccatt ctctcttgaa tttttcttat
    12541 acagaggcac tatttatcaa tcaattctgt gttttagtag cagttatcat cagtagcctt
    12601 acgggcaatg attattttgg gaagcagtcc ttgcctagat tgatgatgtg ggagaccgta
    12661 ggacttagtc tagttggttt ggctaattta ttcaatcaag tcgtgcttgg tttgctattt
    12721 ctcttcttta ctctgtatgt gtctggtaaa gttcaaccaa agattagtgc catgctcatg
    12781 aaaaatctag ctccagaggt tctagctcgt actagtaatt ttttcggtct attgtttacc
    12841 ttatccatac ctgtgggaac agcttgtttt tcactagtag ccgtatggaa catgcagttg
    12901 acttggatgc tatttgttgg tttttccttg ctagctattt tttttgacaa ttcttaatct
    12961 caaaaatgat atttgaacgc gtgagtggag aagttgaaaa tggataagga aaatctcagc
    13021 tatgttggca aaaacttgct cttggtggta attgttttgt taattgctgc tttggtattt
    13081 gtgttaggat tagtgcttgg ttatggtgtc ataggtgatg gtgacaatgt atttgcggta
    13141 ttgtcacctg ctaagtggca ggaattaatc ggtaaattta caggaaagta ggctggtcct
    13201 gcttttttga tggagagaaa atggcgaaga aaaatttgaa aaaacaggca atgagcttac
    13261 tggtgactat aattgcagta gcgggtggtt atcttttaag tgatagccag agtagcactc
    13321 ctgccaatta ttcctattat gtcaatcagt ctaaggcgag tgaagggact cctagtcagg
    13381 aactagctag ttcggtattg acagaagaag tcaaaaagca actggggaat tctattgaat
    13441 ggaatggtgc tggagccttt attattaacg ataatcagac ggatttaaat gcctctgttg
    13501 caagtgttcc ttacggagac aacaagacaa aaacggtgca gggagaaact attccgacag
    13561 tagccaatgc gcttttagca aaatctacac gtcagtataa ggatcgtgaa gaaactagaa
    13621 atggtcggac ttcttggaca cctgctggtt ggcatcaggt ccatgactta actggagaat
    13681 atgaccatgc agtggaccga ggtcaccttc tgggctatgc cttgattggt ggactttcag
    13741 gttttgatgc ttcgaccagc aatcctatag tagattgaaa ctagaatagt acacatctac
    13801 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatt gatttgtcct attcttattt
    13861 cactttacta taaaaacatt gctgttcaaa cagcttggtc taaccaagct aatgaccaaa
    13921 gctctgcggg tcaaaatttt tctgagagcc aaataagacg cgctttggat aaaaataagc
    13981 gtgtccgcta tcgtgtaacc ttggtctatg cagaggcaga tgacctggtt cctgtaggga
    14041 gtcagctaga agcaaaagcg gcagatggaa gcctagagtt caatgttttt gttcccaatg
    14101 tgcagagcgg tctcagtatc aactaccata gtggggaaat tacagtaaat caataaatag
    14161 tcagacgaat tggctgtgtt taaataaaat atatcagatg atttttacgt aaaatcgtct
    14221 ttttttgcgt ataattaaaa atatttacaa aaactgttga caaatcatct gacgaatagt
    14281 agaatatagt taaagaaaac gcttacgact ttgtcgtaga aaacatttag gaggaatttc
    14341 cgatggaaaa acatgttgag caacgtgtcg aagacgttac ttataacaaa gcgaagttat
    14401 ggcaaatcat cttatttgcg atgaataatt cgtcgacgaa tatttacttg gttgccttta
    14461 cttttgtgac ttatttatcg acgggtgtgc ttggtctggc agcgctgttt gttagccaac
    14521 tgatgggcta tattcgtatc tttgatggtt tcattgatcc aacaattggt gttattattg
    14581 ataaaacaga tactaagttt ggtaaatatc gtcctatctt ggttttgggg aatatcatta
    14641 cggctagttc ccttttcatg atgttgggct taagtggagt tagtgagaat ctccgtcttc
    14701 ccttgtttat acttgttttg attatccata aaattggtta ttcattgcaa cagactatta
    14761 cgaaagcggg acaggttgct cttaccaatg atccgaaaca acgtccaatc ttcaatattg
    14821 ttgacggtat tgcaacaaca gtattgatga ctggtagtca ggttgttgta tcaggaacat
    14881 tggttcctaa acatggtggc ttcacaccaa gtttcttcca agaattgttc cttggtgttg
    14941 tgattatttc agctattctg ggtatccttg ctattatcgg tatttgggaa aaagacaata
    15001 agaaatactt tggtcttggc gaaaaaacgc aagaaactaa gttgaaagac tactggaaag
    15061 ttatcaaagg aaataaacct ttgcaggtac tttcaatctc tgcagccttt gtaaaatttg
    15121 ttgctcagtt gttcggtgat tcagttatcg gggttatgct ttatggtatt atcttcggtg
    15181 actatgctct ttctggaaaa atgtcaatgc tcttgatttt gcctggtatc ctcgtaacag
    15241 ttggtgcggc acagttggct cgtcgtaaag gtttacgctt tgcctatatt acagcgcttc
    15301 agttgggtat tgctggtctt gttgccttgg cagcgatgct gttttcagca aaacctggta
    15361 tgttggattt aacaaattgg aatctctaca caatcggttt ctttgttgtt tatatcattg
    15421 cacgttatgc atctggcgct ccatccggtt tggtattgac aatgggtgca gatattacag
    15481 actatgaaac atcagtatct ggtcgttact tgtcaggtat gattggtact atcttctcat
    15541 tgacagactc aattgcgtct tcatttgctc caatggttgt tggttttgtg ttagcaggta
    15601 ttggatttgg taaagaatat ccaactgttg aaacagcttt ctcaactgat ttgagaatgg
    15661 cactaattgt cttgttaaca gtaattccag cagcggtatt gagcgtatcc ttgttcttga
    15721 tgaaattcta caaactagac cgtgaagaaa tggctcgtat tcaagagaaa atccatgtca
    15781 tgaaagcggc aaaagatgaa gaacgagtgc gtgctattgc gaaaaatgtt ccactatctg
    15841 atatggacta cgttgatgta actcagtata aggttgaaca atacgaagat aaataagatt
    15901 tttgaatgta aatagtacaa tgattgacct agttggaggc ttccagctgg gtctttcaac
    15961 taggaggcgg tatgaagaaa attttagcat ttggagaagt tttattgcga ctatctcccc
    16021 cacattatca gactttgaca caggctagga gcttggagtg tcaatttggt ggttcggagt
    16081 taaatgtttt ggctagtttg gctcagctcg gtcattcagt cgagttggtg acggcactcc
    16141 ctaggaatga agtaggcaaa atggcagaac attttctctt tgcacgtcag attggacaga
    16201 aatatttgat tcgaaaagag ggaagactgg gactttatta ttatcaaaaa ggtttttctc
    16261 ttagacccag tcaggtgacc tacgaccgtg attattctgc ttttagccta tcaagggaag
    16321 aagattacga tttggaaggc atatttgaag atgttgattg gttccatgtg agtggtatta
    16381 cagttgccct gaatccagtt attcgtcaac tggcctttcg tttgatggag atggcaaagg
    16441 agcaaggtat taaggtttcc tttgacctga attatcggga aagtttgtgg tcttcttttg
    16501 aggaagctag ggagaagtta tctccttttg taggcttggc agatatttgc tttggtctag
    16561 agcctatcca actcctaaat gaatctggaa aagatatgaa ggatgaactg ggcttgaagc
    16621 gatcttatga aaatagagaa atcctattgt cagtcgttaa agctttagca gaaacctatt
    16681 ctctgcaaag cattgctttt acccagcgag aaatgaccta caataatgaa tacttgctga
    16741 aagcttattt gtatcaagat ggtgttctat acgaaacaga aaaggaatcc attcaagttt
    16801 tagaccgagt tgggacaggt gatgccttta cggcaggaat tattttgggc tatttacagg
    16861 aaaaatcgcc gcaggaagta gtagacttag gaatggctag ttttcaattc aaacatacca
    16921 ttgaagggga tgtcaatgtc atcagtcaat cagatattga tttgttattg aaaaaagggt
    16981 ctcgtgaaat aaaacgatag aaagtaggaa aaatatgttg tatccaattc aaacgaaaac
    17041 acgctcagtt tattctttaa acggaatatg ggcctttaag caaggaaaca atgatgttca
    17101 atctttgtta gatacggatg aggtaatggt tgtaccaagt tccttcaatg atattgttgt
    17161 tgacaaagag aaacgccgtt ttgtcggaga taattggtat gaactgatgg tggctatccc
    17221 tgctgtgtct gatgatgaag aattagtggt gcgctttggc tccgtgacgc atcaggctat
    17281 ggtctatgcg gatggtcagt taatcgggaa gcataagggg ggctttaccc cttttgaatg
    17341 cctggttccg tcggaattat atggtttgga tcaattccgc ctgacagttt gtgccaataa
    17401 tgagctgaat tatacaaccc ttccagtagg gaattacagt gaagaggtag atgaaaacgg
    17461 tcaaattgtg aagacggtca aggaaaattt tgactttttc aactatgctg gtattcagcg
    17521 gaatgttcat ctctataaac gtccgaaaaa tagggttgat gatattgtta ttcggactga
    17581 actgaataat gaattgactc aagctgttgt tcatgttgag gtggcgacag ttgggcagta
    17641 tgattctatt cgtattcaca tttttaatca agaaggacag gaactaggtc ttcttgaaaa
    17701 tggacggata gtcattgata atccccgcct ttgggaagtt ttagatgcct atctctatac
    17761 tgcaaaagtc gaattatttg atggtgagag cttattagat acttactgcg aacagtttgg
    17821 tcttcgtagt gttgcagttg agaatggaca atttttcatc aacggaaaac cgttctattt
    17881 caagggattt ggtaaacatg aagacacctt tatcaatggc cgcggcttca acgaagcagc
    17941 taatctgatg gatttgaact tactcaaaga tattggagct aattcattta gaacgtccca
    18001 ttatccatat tctgaagaaa tgatgcgact ggcagatcga ttgggaattg tagtcattga
    18061 cgaggtgcca gcagtcgggc tgttccagct tttcaatgca gccttgaatt tgacagggga
    18121 ttctgatgag gtaaaaaata cctgggaagt catgcaaacc aaggatgctc atgaactagt
    18181 gattgatgaa ttgatagcgc gtgataagaa ccatccatcc gtagtgatgt gggttgtagc
    18241 caatgaaccg gcagggcatg aaaaaggtgc acgtgcttac tttgaacctc tgattcagcg
    18301 aatgagagat agagatcctt ctaaccgtcc tgtaaccttg gttaatatta tgacggcaac
    18361 acctgataaa gatgaagtta tggacttggt tgatgttgtc tgtctcaatc gttattatgg
    18421 ttggtatgct gctcatggcg acttgaagat ggcagaaaaa ggacttcgaa aggaactaga
    18481 gacatggcaa gaactatatc cagacaagcc tattttgatt acagaatatg gtgcagatac
    18541 tctcccaggc ttgcattcaa tgtgggatat tccttatacg gaagaatttc aagtggatta
    18601 ctatgatatg aatcacaggg tttttgattc tatttcaaat gtggttggtg aacaagtctg
    18661 gaattttgct gattttgaaa ccacagttgg tctcattcgg attcaaggaa atcataaggg
    18721 tttattctca cggaatcgtc aacccaagca aattgttaga gaaataaaga aacgttggac
    18781 tgccattcca aactaccatt ataaaaggaa ataggctata atagtagcaa atagaaagtt
    18841 gtattggagg accaagcaca tggcgaaacc cttggtagaa aaagcatcag aacgcttatt
    18901 ggaattgatt ttggaaagag gatatgaggt tggagacaag cttccaaatg agtatgaatt
    18961 agcccaagat ttagaagttg gacgttcgac tgttcgtgaa gctgttcgga gtttggctac
    19021 tcgcaatatt ctggaggtgc gccaagggtc agggacatac atcagctcta aaaaaggagt
    19081 atcggaagac cctctaggtt tttctttggt aagagaccgt gtgaagttga caacggattt
    19141 gtttgaagtg cggtacttac ttgaaccgag aattgcggag cgtgtagctc aatttgcttc
    19201 ggatgaagat gttgctaaat tagaggaaat tgtccttgca attgaagagg ctgtagctgc
    19261 tggagacacg aagcatttgg agttggatgt gaaatttcat tgtatgctgg ctgagatgag
    19321 tgggaatctg gcaatgacta gcctgatgcc tgtcattaat cagtccattc atctgatcaa
    19381 tgaaaattac tcaaatcgtc agatgaaatc aaatagttta caggcgcaca gaaatatctt
    19441 aatggcaatc aaacaacgcc accctgttgc agcttatgat agtatgttag cgcatattat
    19501 atcggtaaga caggttgttt taagcgaatg gttcgataaa gacatgacct tgcatggtct
    19561 aaatgatcat aaatagaaat ataaaacgaa ctgcccagaa gagtcttctg ggtatttttt
    19621 tgctttttcc ttgacaaatc atctgatgaa ttatatacta taactataaa tagcaacgct
    19681 ttctaattgg aggttaagat gttaagacaa ttaaaagaaa attacttttt cgcagtgatt
    19741 cgcggaaaag atgaacaaga tgcaaaagaa attgctcgtc atgcggtttt aggtggtatt
    19801 cgaaatatcg agattacatt ttcgacgcct aatgctgcga cagtcatcaa agaattacaa
    19861 gaagagttct cagatgattc gtctgtagtc atcggtgcag gcacagtaat gaatcttaat
    19921 ctcgcacagg aggcgattgg tgcaggggct agttttcttg ttagtcctca ttttgataag
    19981 aaaatccaag agttagcgca agagacaggg gttctctatt ttcctggttg tgcaactgca
    20041 acggaaattg ttacagctag tcaggctggg tgttctatta tcaagctttt ccctggtggt
    20101 gtattgggac atgggtttat caaagatatt cacggtcccg tccctgaagt ggacttgatg
    20161 ccatctggtg gagtatctgt tgacaatgtt gcggattgga aaaaggccgg tgcttgtgct
    20221 gttggaattg gttcggcatt ggcgagtcgg gtgcaggctg agggctatga cagtgtaacg
    20281 ttgattgctc gtagttttgt agcagctttg gagggataag atgagtttta acgataaaaa
    20341 ctttatgcta aaaaatgaac ctgctaagga gctttacgtg aaaatagcag agctacctat
    20401 ctatgatttt cattgtcact tggatcctaa ggaaattttt gaagacaagg tctatgaaga
    20461 tattgttgat ttgtggctag gtggagatca ctataagtgg cgcttgatgc gggctaatgg
    20521 aatttcagaa gaagagatca caggatttgc aagtaagtta gataaattta aagcctgggc
    20581 aagaactttg gaacgtgctt ttggaaatcc tctctaccat tggagtcatt tggaattacg
    20641 acaagttttt ggtatcgagg aattgctgac ggaagaaaat gcagagcgtc tctatcatca
    20701 gctcaatacc tatttgcaag aacatcaaat tagtccacgt aagctgatcg ctgatgccag
    20761 agtggccttt atcgggacaa ctgaccatcc tcttgataac ctagaatggc ataagcgttt
    20821 ggcagaagat tcacccattg acactgtagt agcgccaacc ttccgtccag atgaagcctt
    20881 tatagaacac agaaatttca atttatttat taaacgcttg gaagaagtga cggaggtagc
    20941 agtaagagac tttgccagtt ttgtagaggc tttgggccaa cgagtttcct attttgctca
    21001 acatggttgc cgagcaagcg atattagttt tacagctatt acctatgaag aagctacact
    21061 tgaagaactg aatgatattt tacttgctag gatggtaggg aaagaggtcg gacaatctgg
    21121 gatcaataag tggcagacag ctatttttag agaactctgt cgtatgtaca agaaacatgg
    21181 atttgtcaca caagttcatt ttggtgcctt acgaaacaac catacaggac tgtttgaaaa
    21241 acttggagca gatgtaggtg tagattcgat tggagaccag acgtgcttga cggggaactt
    21301 gaatcgtttg ttggacaact tggtcaagga aaatgccctt ccaaaaatga tttggtacaa
    21361 ccttaatcca ggctacaata ttgccctagc caacacctta gcaaatttcc aagccaatga
    21421 ggaagggcgt cgtagtcagt tgcagtttgg tgcgggttgg tggtttaacg ataccaagct
    21481 aggcatgatt gaccagatga atgcctatgc cgagcaaggt atgcttgcta attttgtagg
    21541 gatgttgaca gattcgcgta gcttcttgtc ctaccaacgc catgattatt tcagacgaat
    21601 tttggcgacc tatgttggcc aatggattgt ggatgaggaa gtgcctgagg actatgatcg
    21661 cctaggtcag tttgtagaag caatatctta ctacaatgcc aaagagtttt ttgaacaata
    21721 aaggagagta aatcatgaaa atgtcatttc gatggtatgg aaaaaaagac cctgtgacac
    21781 ttgaagagat taaagcaatt cctggcatgc agggaattgt gacagctgtc tacgatgtgc
    21841 cagtaggtca ggcttggcct ttggaaaata ttcttgagtt gaaacaaatg gtggaagagg
    21901 caggtttaga gattacagtt attgagtcca ttcctgtcca tgaagatatc aaacaaggca
    21961 aaccaaaccg tgatgagctg attgaaaact ataaaacatc tattcgtaat gtcggagcgg
    22021 caggaattcc agttgtatgc tacaacttca tgcctgtatt tgactggaca cgttcggact
    22081 tgcatcatcc tcttccagat ggttcaactt ccctagcctt tctgaaatct gatttagctg
    22141 gtgttgatcc tgtggcagat gacttgaact tgccgggttg ggattcatct tattccaagg
    22201 aagaaatgaa gaacgttatt gaaaattatc gtcagaatat ttctgaggaa gatttatggg
    22261 caaacttgga gtatttcatc aaggcgatta tgccaacggc tgaggaagca ggagtgaaaa
    22321 tggcgattca cccagatgat cctccgtatg gaatttttgg attgccacgt atcattactg
    22381 gtcaagaagc tgttgaacgc tttttgaatc tctatgactc agaacataat ggaattacca
    22441 tgtgtgtcgg ttcctatgct tctgatccga aaaatgatgt cctcgccatg acagaatatg
    22501 ctctcaaacg caaccgtatc aattttatgc acactcgtaa tgtgacggca ggggcttggg
    22561 gcttccaaga aactgcacac ttgtcacagt ctggcgatat tgatatgaat ggagtagtta
    22621 aactcttggt ggactatgat tggcaaggag ctttgcgacc agaccatggt cgacgtatct
    22681 ggggagacca aactaagaca cctggctatg gtttgtatga ccgtgcactc ggtgcgacct
    22741 attttaacgg tctctacgaa gcgaatatgc gagcggcagg taagacacca gattttggaa
    22801 ttaaagtaaa aacagttggg aataaggagg gctagttatg acacgtgtta ttgaatttaa
    22861 agacaaggtt gttgttatta ccggagctgg aggcgttctt tgtggttatt tggcaaaaga
    22921 atttgcgaag gctggtgcta aagtagctct tttggactta aatgaggtag ctgctcaagt
    22981 gtttgttgat gaaattgagt cagtaggtgg agttgcaaag acctataaat ctaacgttct
    23041 ttctaaggaa aatttggaag aagttcgcca acaagtctta gcagattttg gtccagttga
    23101 tatcttggtt aacggtgccg gaggcaacaa tccgaaagca acgacggaca atgagtttca
    23161 tgaaattgga cttcctgtgg acaccaaaac tttctttgat ttggacgagg cgggaatcaa
    23221 ctttgtattc aatttgaatt atttaggtac tctcttgcca actcaggtat ttgcgcagga
    23281 tatgattggc cgtagcggag caaatattat taatatttct agcatgaacg ccttcacacc
    23341 attgactaaa attccagcat attcaggggc caaagctgcc atcagcaatt ttactcagtg
    23401 gttagcagtg catttttcaa aagttggaat ccgttgcaat gccattgcac caggtttctt
    23461 tttaaccaat cagaaccgcg gcttgttatt tgatgagtca ggtcaaccga cagcacgtgc
    23521 caacaagatt ttgaccaata caccgatggg acggtttggc gaagcagaag agctagttgg
    23581 aggtgtcttc ttcttagcag atgagaatct ggcaagtttt gtaaatggcg ttgttttacc
    23641 gattgacggt ggattttcag cctattcagg agtctaatca tgaagacaga ttatgtattt
    23701 tgtgtggact ctgatggctg tgcaatggac accatgacct acaaacataa gctcttcttt
    23761 ggccccttgg cagcagatgt ctttggagtt caagataggg aggctttctt aacggaatgg
    23821 aatcgagtca atctctattc acgaacacgt ggcattaacc gttttgtcgg gttggttaaa
    23881 ggtttagaat ttgcaggtgt gactggtatt gaacagttga aaaattgggt tgcgaccaca
    23941 gattctttgt caaatgcttc tctggaaaag ctgatagcgg agcaaccatc gaaagattta
    24001 gaattagctt tagaatggtc caaacaagtc aatcaagcta ttaagaacta tactggtcct
    24061 gttttagcat tcatcggcgt tcacaaaggc ttggaaaaat tgagccagtt gggaaaagta
    24121 tatgtcgttt cttcagccaa taaagaagcg gtcgacgaag agtggtccga gcaaggatta
    24181 ctggattttg ttactgaact ttattgtcaa gatcgaggca agaaggagga tgtgataaag
    24241 ttattgattg ataagggtta taaccctgat aacatcataa tgattggtga ttctcctggt
    24301 gatttgaagg ctgcagaact gaataatgtc cacttctatc ctattttagt aggacgggag
    24361 atgcgatctt gggcagattt aacagaaacg attgcagatg actttgttaa tcaaacattt
    24421 gcaggtgaga aagaaacaaa cttgatacaa gcattttgga aaaatttaga cgactagata
    24481 agggctagag gctacatgcc ctctagcttt tttggaggca acgatgacac atttggtaga
    24541 cttacggaag aaaccttata accttgatga agaagctatt tcatgggttg aaaatacgat
    24601 tgctcagatg acattggatg aaaaaatagg acatctcttt gtcaacatgg gtatccagcg
    24661 gacggagaaa tatctgacag gagtattgga agattacaag attgctgctg ttcggtataa
    24721 tccagggcca gcggcagata tttgggaaca aaactatatt ttgcaaacta agtccaaaat
    24781 tcctctctta atagcagcaa acacagaatc tggtggaaat ggtgctgtta cagatggaac
    24841 aaaaattggc gatgaaatca aaattgcagc aacagctgat tctcgccatg cttatgagat
    24901 ggggaaagtt gcagggattg aagcagcagc agtaggctgt aacgcttcct ttgcaccgat
    24961 tatggatctt agccgcaact ggcgaaatcc aattatcgcc aatcgtactt ggggagcaga
    25021 tgttgaccaa gtgattgaac tgtctaaaga atacatgcgt gggattatgg aacatggcat
    25081 tgtgcctttt gcgaagcatt ttcctggcga tggtattgat gaacgcgatc accacctctc
    25141 ttttgcttct aatccaatga caaaatctga atggatggaa acctttggac ggatttacgg
    25201 tgaaatggct gatgcaggtc ttccaggtat catggcgggg cacattcatt tgccaaatgt
    25261 tgagaaagaa atgcatccag aacgtgaatt ggatgatatg ttgccagctt cgttgaataa
    25321 aaccctcttg gatgaattgt tgcgtgggga gttaggctac aacggcgcaa ttgtgacgga
    25381 tgctagtcac atgattggta tgacagcatc tatgccacgt cgtgagctct taccgacagc
    25441 tattgaagcg ggctgcgatc tcttcctctt tttcaatgat cctgaagaag atttgcaatg
    25501 gatgaaagag gggttgaaaa atggacttct cactgaggag cggctccatg atgctcttcg
    25561 tcggaccttg ggcttgaaag ctaaactcgg cctccacctt tttgaaggtc gtcgtcagga
    25621 aattatgttg ccaaaagaag aagcgctggc tttaattgga aaagatgagg ctaaaaatct
    25681 tgcaaaagaa gtagctgaca aggctattac cttggtaaaa tccaagcaag aaggcatttt
    25741 cccagtcaat ccagatcgct ataaacggat tttattggtt gaagtcgacg gctacaaagg
    25801 tggctttggt gccatgatta atgcaggaaa gaagagggcg gctgatacgc taaaagaatt
    25861 gttagaagca cgaggtcacg aagtgtctat ctgggaaaat acagaagcaa ggattgccaa
    25921 attaccagaa gaagaaagac cagctgcgat tgctaatgtc tatgcatcta agcgtcctat
    25981 tgcagaaatc acagataact atgatttgat tatcaatttg gttgatgtca attcaggtgg
    26041 aacaactcaa cgaattattt ggcctgctgc caagggaaca ccagatcagc cgttctatgt
    26101 tcatgaaata ccaaccatcg ttgtttctgt tcagcatccc tttgctctgg cagatatgcc
    26161 acaagtagca acctatatca atgcctatga tggtttacca gtaactttgg aaaccttagt
    26221 taccaaacta gcaggagaat catcgtttac aggagtgtcc cctgttgatg cttactgtgg
    26281 cttggtagat acacatattt ggcgtgggaa ttaaggagac agcaatgcct agactagttg
    26341 atttaagaaa gaaaccatat tacttgaatg atgatcagat tgtctgggta gagagtaccc
    26401 ttgaaaatct gacagatgaa gaaaaaattg gccaactttt tgtcaacctc ttcttctttg
    26461 gcggtgatgc ctttagcggg aataatctga gcaatcagga gctgattaat cgataccaca
    26521 ttggcggtgc tcgttatatg aatggtagtc ctgagcaagt acaggggctt atcaatgact
    26581 tacagtcata ttcaaaagtt cctctccttg ttgcagctaa ctgtgattcc ggtggagatg
    26641 gagctgtgaa aggtggaact tacatttctt caggtgccca gtctgaagcc agtcgtgatt
    26701 ctcgcattcc atatcttgca ggtcttgtat ctgcgaggga ggaaactgca ttgggtgtca
    26761 atgtcaattt tgacccatgc gtagacatcg ttcaaaactg gcgcaatacc attgtgaata
    26821 ccagagctta tgggaccaat gctgacgatg ttattgctta taccagcgcc tatttagagg
    26881 gtttgactgc cgaaagagat gttattcaat gcataaaaca ttttccaggt gatgggacag
    26941 aagagcgaga tcagcaccta gttctcggtg tcaatgagct atcaccagaa gagtgggacg
    27001 atagttttgg tcgtgtctat caccaccata ttgaagctgg tgtagagatg gttatggctg
    27061 gtcatatcgc cttgctatat tatcaacaaa aattgaaccc tagtttaaag gatgaggata
    27121 tcttaccagc aacactagct cccgaattga ttcaagattt attgaaagaa aaactggaat
    27181 tcaatggctt ggttattacc gatgccagtc acatgctggg gatgacagcg gctatgcgtc
    27241 gcgaagacta tgtaccagct gccattgcag cgggttgtga tatgttcttg tttttcaata
    27301 acctggaaga agattttgag tttatgctga acggttacag aaatggcgtg attaccaaag
    27361 aacgtcttca tgatgctctt cgccgcattt taggattgaa agccaaactc aatcttcatg
    27421 tcaaacaagc agaagggact ctgttgaaat ccgctgatga gttggcaatt attggatgtg
    27481 aagaacattt ggcttggcaa cgtgaggcgg cagataaggc gattactctt ttgaaagata
    27541 cccaacacaa tcttccaatc agccctgaaa ctcatcgaag gatccgctta tattacttag
    27601 aaggggaaaa agaggggatt atggcggcaa gtacagaagt agtagataat ctcaaatccg
    27661 ccttggaagc gcgtggctat gaagtgactg tcaatgatgg tactactcgg attaaaggaa
    27721 aaactctaca atatcgagaa gaagtagatt tagcattgac ggttgccaat gtcatcggat
    27781 acggtgcgca gaataattac cgtatccaat ggaaaacagc catgtccaat gaagttcctt
    27841 ggtatgttca tgaagtatca accatctttg tttctctcaa ttacactacc catcttcacg
    27901 atgttaccat ggtgaaaaca gctatcaacg cctatcacca caacaaaaat accattgaat
    27961 ccctccttga taaattggaa ggtaaagatg agttctatgg tattccaaat gaaaatgttt
    28021 gggccaataa gtggcaagcg aaactataaa tgtaagctcc tttctatcgt agatagaagg
    28081 agttttttag caagatttct tgccaaatga cctgcatttt gatagaatat tcttaattga
    28141 atagaagttt gtgagactag tacacctatg gaaactgtcc agggagttga gccgtgactg
    28201 aaagctcaat cagtgaaagt tggtcgaatt cactcatata aggacttaga ataaaggtct
    28261 gcctagcaga tgaaaacgga tggtgccgcg tgacaacgct ccgatacgaa tggtgtcatg
    28321 cgtttttttt attggaggaa ttatgtcaaa cattgaacaa cagttggctg agttgcgtca
    28381 aagcacgctt gatagactaa aagaaattca ccatgaaggt gagaaagaat tgcaagacct
    28441 acgtgtctct gtcttgggga aaaaaggctc gttgacagac ttattaaaac cccaattatt
    28501 caccccaaat ctaaaaacca tccagaatcc ttgccttagc ttagatcctg gatggtttct
    28561 tttttcaccc aatgggtgtt ttttactaga caaaaaagag tttccccttt atggaataag
    28621 tgtagaaaaa aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa atcatcactt
    28681 ccaaaacaag tctttttacc aactatcttt cgatggaggt catttaaccc agtatggtgg
    28741 tcttatcttt tttcaggaac ttttttccca gttgaaacta aaagagcgga tttctaagta
    28801 tttagtaacg aatgaccaac gccgctactg tcgttattcg gattcagata tccttgtcca
    28861 gttcctcttt caactgttaa caggctatgg aacggactat gcttgtaaag aattgtcagt
    28921 tgatgcctac tttccaaaat tgttggaagg agggcagctt gcttcacagc caaccttatc
    28981 ccgttttctt tccagaactg acgaggaaac agtccatagt ttgcgatgcc tcaaccttga
    29041 attggtcgaa ttctttttac agtttcacca gctaaaccaa ctcattgtag atatcgattc
    29101 tacccatttc acaacttatg gcaagcaaga aggtgttgct tataacgccc actatcgtgc
    29161 tcatggctat catcctcttt atgctttcga ggggaagaca ggttattgtt tcaataccca
    29221 gcttcgtcct ggtaatcgtt attgttctga agaggcagac agctttatca cacctgtttt
    29281 agaacggttt aatcaacttc tctttcgaat ggatagtggc tttgcgaccc ccaaattata
    29341 cgatttaatt gaaaaaacag ggcaatacta actcataaaa ctcaagaaaa atactgttct
    29401 gagccgtctt ggagaccttt ccctcccttg cccacaggat gaggacttaa ccatcttgcc
    29461 ccactccgcc tactcagaaa ctctctatca agcaggatct tggtcgcaca agcgtcgtgt
    29521 ctgccagttc tctgaacgaa aagaaggaaa cttgttctac gatattattt ctctcgttac
    29581 aaatatgacg agtggaacaa gccaagacca gtttcagctt tatcgtggac gtggtcaagc
    29641 cgagaatttc atcaaggaga tgaaggaggg attttttggc gataaaacgg atagttcaac
    29701 cttaatcaaa aacgaagttc gtatgatgat gagctgtatc gcctacaatc tctatctttt
    29761 tctcaaacat ctagctggag gtgacttcca aactttaaca atcaaacgct tccgccatct
    29821 ttttcttcac gtggtaggaa aatgtgttcg aacaggacgc aagcagctcc tcaaattgtc
    29881 tagtctctat gcctattccg aattgttttc agcactttat tctaggatta gaaaagtcaa
    29941 cctgaatctt cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa tgatgcatta
    30001 aagaacagtc gagatgaaaa aatcgtgtga cgcaccaagg gaggagtctg cccttttgag
    30061 gaaatctagc gaggaaaaac gatactggaa cagcagaaag taaaactgac ctcatgagga
    30121 ggaagaaagt ggctcatgag gtcaggggtt ttgtaagtta catctagttg agagaggtat
    30181 gaatgatttg ggttaaatcc taattttttt ctcactgttt taatcccttt atttgtggta
    30241 aaataagact attaagttta aagaggattc cctatgaaat tacaaaaacc aaaaggaacg
    30301 caggatattt tacctgctga atctgccaaa tggcagtacg ttgagggctt tgcccgtgaa
    30361 attttcaagc gctacaacta cgcagaagtg cgtacgccta ttttcgagca ttacgaggtt
    30421 atcagccgct ctgtcggaga tacaacagat atcgtaacca aggaaatgta cgatttttat
    30481 gacaagggtg accgtcatat taccctccgt ccagaaggaa ctgcgcccgt tgtccgttcc
    30541 tatgtggaaa ataaactctt cgccccagaa gtgcaaaagc caagcaagtt ctactacatg
    30601 ggacctatgt tccgttatga gcgtccacag gcagggcgct tgcgccaatt ccaccagatt
    30661 ggtgttgagt gttttggctc tagcaatcca gctaccgatg tggaaacaat cgttatggca
    30721 gcccattttt tgaaggaaat cggtattcaa ggtgtcaaat tgcacctcaa cactcttgga
    30781 aatcctgaga gccgtgcagc ctaccgccaa gccttgattg actatttgac accgctcaag
    30841 gagaccttgt ctaaggatag ccaacgtcgc ttggaggaaa atcctcttcg tgtcttggac
    30901 tctaaggaaa aagaagacaa ggtggcagta gagaatgcgc cgtctatctt ggactttctt
    30961 gatgaagaaa gccaaactca ttttgatgct gtgcgtcaga tgttggaaaa tcttggagta
    31021 gattacatca tcgataccaa tatggtgcgt ggtctggact actacaacca caccattttc
    31081 gagtttatca cagagattga gggcaatgac ttgacagtct gtgcgggtgg tcgctacgat
    31141 ggtttggttg cttactttgg aggccctgaa actgctggat ttggttttgg gcttggtgta
    31201 gagcgcctgc ttctcatcct tgaaaaacaa ggcgtggccc tccctatcga aaatgcccta
    31261 gatgtctata tcgcagtctt gggtgatgga gcaaatgtca aagccctaga actagtccaa
    31321 gctcttcgcc aacaaggttt caaagcagag cgtgattacc tcaaccgtaa gctcaaagct
    31381 cagttcaagt cagccgatgt ctttgcggct aagaccctca tcaccctagg agagagcgaa
    31441 gtcgaaagca gacaagtgac agtcaagaac aaccaaaccc gagaagaagt gcaagtgtca
    31501 cttgagacaa tcagccaaaa cttctcagaa atctttgaaa aactaggatt ttatactcaa
    31561 taaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg
    31621 ttgtggatag aactgacgaa gtcagctcaa aacatggttt tgaggttgta gatgaaactg
    31681 acgaagtcag taaccatacc tacggcaagg tgaagctgac gtggtttgaa gagattttag
    31741 aagagtatta atgatagata aagtggtcag gaacttactc ctgacctttt tcttttgcaa
    31801 aatgacaaaa atcataaact ttttgacaaa tatacttatc aaaaagaaaa agatgtgtta
    31861 caatgtaagc aagttaagag aaaagaagaa aggagctatg atgtgggtac taggatttat
    31921 actatttctg attttctttt attctaatga ttctaaaaaa atcaagaaac tagagaagaa
    31981 aatcaaaaga cttgagcgaa aagagaaagg aaacgcagaa atgtcgagat tattacaaga
    32041 aatgattgga aaggaaccaa ttataacggg agtgtatatt ggcccagata actgggaagt
    32101 tgtggatgtt gatgaggaat gggtaaagct acgacgtgta gataatacgg gaaaagaaaa
    32161 attcaagttg caacgtattg aagatatcca aaccgttgaa tttgacggag agtaggtgtg
    32221 taacatgcaa ctaaaaaatc gtctaaaaga gcttcgagct cgtgatggtc tcaatcaaac
    32281 cgacctagcc aaactggcag gggtttccag acagaccatt agcctactag aacgggatga
    32341 gtacacccca tccattatca ttgccctgaa aatatctcaa attttcaacg aaacagtcga
    32401 atcggtattt cgtttggagg aggacgagtg atgaacaagt ataaagtgat ttattatgta
    32461 gtggtcatag ctttattagt cagtgtattt ctactgattg ggatggactt aagctggttt
    32521 aatccctatc aaagcgacca atttgtttgg gtctactttg ctctcatccc agtaattgaa
    32581 tggattgaaa agaaatccaa aaatctagca agtgaaaaag gagaatgaat atgaaaaaga
    32641 aacgtagatt gttatttttg atgtctattg tcttgggggg gttcttgggc atgtttgtag
    32701 ggatgtttaa ggcacgtgtc gaatcccacg aaattatttt agatgtaaaa gccttgatgc
    32761 catggatatc agctatttgt ttactgatag gtttcattag tatgtttttg actttcaatt
    32821 tcttaaagaa aagtagaaaa tttcattcct tgtatcaaga ggaaatggat gacgatctga
    32881 atgaaaccta ttatgtgcaa atgtatcgga atcttgagtt tggaaccatt gcttttaata
    32941 ttacaggtgt agcgattcca ttggctattt ttatttcatt aagtgaggtg attatattgc
    33001 atacaaaccc tcaaacattt ttcctttctt tcttactctt tgtggtattc ttagtcgctc
    33061 aaaaatctct ttttaaaacc attgcgattg ttcgtcagtt tgatttggaa tttttcgcta
    33121 caccaaagga tgtcttgaac tatataaatt cttatgatga aggggagcgt caggctaatt
    33181 tggaacagag ttttcgaatt ttattccaat tacaccaata tgtcttacca gccttatata
    33241 tttttcttat tatcctttct ttcttgacag gagagattca gttactagct ttcttgcttg
    33301 taggagccat ccatgtttat atcaatgtga tgcagttacc tatggtaaaa cgttatttca
    33361 aataaaggag ttatctatga aattacttaa aaaccttggc tggattcttc tagcccttct
    33421 atccttttta tttatctatg gctttattca ggggctcgcg actgcgtcgc ttgctttagg
    33481 cgcttcaccc tatgctgtta ctctactcta tgtggtcttg gctggagtat atgtgtacgg
    33541 catttacaaa tggtatcaga aagctcctgt ttatattgag aagagcggct ttaaccgatt
    33601 tatttggctt cctgtcttgg tttggttctt atctctggtc gttcaattct tcttgccaga
    33661 tgatccttca gtaaatcaac aaatagcgac agacttgacc ttgtctcaac cacttttctc
    33721 attctttgct gtggttattt ttgctccttt gacggaagag attgttttta gagggatgtt
    33781 agcacgctat ctctttccta agcaggacaa tagtaaacga accctgattt ttcttctggt
    33841 atctagtctt ctatttgcct tgattcattt tccaggtgat gtgcaacaat tttttgtcta
    33901 ttttagcctt ggttttagtt tgggtttggc ttacattagc agaaaaggtc tggtctacag
    33961 tatttctctt cacgctttga ataatttagt cggctttttg atgattctca tgctataata
    34021 gagtcaggag gtcacatgaa acgagtaatt ttagtagcag tgattcaggc agtcgttcta
    34081 tttttcatca ttggagcgct agcttatgcc ttcaaaggcg atttcttcta taactatcta
    34141 gcagttgtct ttgctcctat tgcaggtgta ctgcgttttg ggacggctta cataacggaa
    34201 attgtcttgc ctcgaaaggc agccgaaatc gctgaaaagc gtaaagcagg caaaaaatca
    34261 aaataaaaga gtccggtgaa gttcatcgga tttttgtatt atactcaatg aaaatcaaag
    34321 agtaaactag gaagctagcc gcaggttgct caaaacactg ttttgaggtt gtggatgaaa
    34381 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
    34441 accataccta cggtaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtattagc
    34501 gctaattttt agggctttca cctgactttt aaagactggc aaacttttct gatgattttc
    34561 atgaagagcc tgcgctttta tggtaaaata gtaacagaat aaaagaggag agaaataatg
    34621 aaacgtagta tgtatgctgg tcgtgttcgt gaggaacaca tcggacaaga aataaccttg
    34681 aaaggatggg ttggccgtcg tcgtgacctt ggtggtttga tctttatcga tcttcgtgac
    34741 cgtgaaggaa tcatgcagtt ggttatcaac cctgaaaaag tatctgcaga ggttatggca
    34801 acagctgaaa gccttcgtag cgaatttgtt attgaggtga ctggtcaggt cgctgcgcgt
    34861 gagcaagcca atgataagtt gccaactggt gcggttgagt taaacgtgac agctcttatt
    34921 gtgcttaaca cagctaagac aacaccattt gagattaagg atggcattga ggcaaatgac
    34981 gatacacgtt tgcgttaccg ttaccttgac cttcgtcgtc cagaaatgtt ggaaaatctt
    35041 aaacttcgtg ccaaggtgac ccactctatc cgcaactact tggatgagtt ggagtttatc
    35101 gacgtggaga caccattcct ttctaagtca acgcctgaag gggcgcgtga ttatttagtg
    35161 ccgtctcgtg ttaataaggg gcatttttac gctcttcctc aaagtccaca aatcacgaaa
    35221 cagctcttga tgaatgctgg ttttgaccgt tactaccaaa tcgttaaatg tttccgtgac
    35281 gaagacttgc gtggagaccg ccagcctgaa tttactcagg tcgacttgga aacgtccttc
    35341 cttactgagc aagaaatcca agatattaca gaaggcttga tcgcgcgcgt gatgaaggaa
    35401 acaaaaggca tcgaagtaac gctaccgttc cctcgtgtga aatacgatga tgctatggct
    35461 ctttacggtt ctgacaagcc agatactcgt tttgacatgt tgcttcagga cttgacagaa
    35521 gtggtcaaag gtgtagactt taaagtcttt tcagaagcac ctgctgtaaa agcgattgtg
    35581 gtcaaaggag ctgcggacaa ctattcacgt aaagacatcg acaagatgac ggaagtagcc
    35641 aaacagtatg gtgccaaagg tcttgcttgg gttaaggtgg ttgatggaga attaaacgga
    35701 ccagttgcca agttcttgac tggtatccaa gaagaattga caacagcgct tgctcttgaa
    35761 gataaggact tggttctctt tgtggcggat acgcttgaag tggctaatgc aacactgggt
    35821 gcccttcgtg gacgtattgc taaagagctt ggcttgattg ataatgataa gttcaacttc
    35881 ctttgggtgg ttgactggcc gatgtttgaa tggtctgaag aagaaggccg ctacatgagc
    35941 gcccaccatc ctttcaccct tccacaggaa gagactgctc acgaattaga aggtgatttg
    36001 gctaaggttc gtgccattgc ttacgatatc gtcttgaacg gttatgagct tggtggtggt
    36061 agccttcgta tcaaccaaaa agaccttcaa gaacgcatgt tcaaggctct tggtttctca
    36121 gctgaagaag ccaatgacca gtttggtttc cttcttgaag ccatggacta tggtttccca
    36181 ccacacggtg gtttggctat cgggcttgac cgttttgtca tgttgcttgc tggagaagaa
    36241 aatatccgtg aagtcattgc ctttcctaag aacaacaagg caactgaccc aatgacacaa
    36301 gctccatcaa cagtcgctct caaacaacta gaggaactca gcttacaagt agaagaagat
    36361 gaaacaaaca aaacgaatta agcggtggcg ctattatctg cgccgctttg cttatcagat
    36421 aaaaatttta cgtgtcttac aaagtatctc tcgagaaaag tatgatgaga agatttcggc
    36481 ctctctggtc tatggttttt tatcagcagt agcagttaat ttctttttcc aaccagggca
    36541 tgtgtattcg agtggtgcaa caggtctggc acagattatc tctgccttga gtaatcactg
    36601 gtttggtttt catattccga tttcgctaag cttctacgcc attaacttcc ctttgatggt
    36661 cttagcttgg tatcagattg gccataagtt caccgtcttt acctttatca cggtatctat
    36721 gagttcctta tttatccagt ttgtccctgt ggcaaccttg acggaggatc ccattatcaa
    36781 ttcccttttt gggggtgttg ttatgggttt ggggattggt tttgctcttc gaaacaatat
    36841 ctccagtggt gggacggata tcgtcagcct gactattcgc aagaaaacgg gtaagaatgt
    36901 cggtagtatt tctttcttgg taaatggaac tatcatgctg atagcaggtt tgacctttgg
    36961 ttggaaatac gctctttatt ctatgattac catctttgtc tctagccgtg tgacagacgc
    37021 agtctttact aagcaaaagc gtatgcaggc catgattgtg acaaatcatc cagagaaggt
    37081 aattgaaaaa atccataaaa aattgcaccg cggagcaacc atgatccacg atgcagaagg
    37141 aacctataat cacgagagaa aggcagtttt aatcactgtc attacacgtg cagagtttaa
    37201 tgaatttaaa cagattatga cacaagtgga tccaagctcc tttgtctctg tctcggaaaa
    37261 tgttcatatt ctaggaagat ttgttgagat agataattag tgattaatac tcttcgaaaa
    37321 tctcttcaaa ccacgtcagc gtcgccttac cgtatatatg ttactgactt cgtcagttct
    37381 atctgcaacc tcaaaaccat gttttgagct gacttcgtca gtttcatcta caacctcaaa
    37441 accatgtttt gagctgactt cgtcagtttc atctacaacc tcaaaaccat gttttgagct
    37501 gacttcgtca gttctatcca caacctcaaa acagtgtttt gagcaacctg tggctagctt
    37561 cctagtttgc actttgattt tcattgagta taaaaagatc ttgggaaaag actcaatttc
    37621 agtagaaaag gaagtaaatc ttcccacaat aaaacgcata gtatcaagtt ttttcaatac
    37681 ctgatagtat gcgtttttgc ttttaacgac tttttgccca gtctcttatt tttcgataat
    37741 tttgtgggcg atcaattgac ggtaacaaat ttgtttattg tttttattat cattaataat
    37801 ctggagaata gtttcaaggg aaacacgacc aagctctaaa ctattgatat cgacataggc
    37861 tgccaagttg agcttgggat taaccgagtc aaagctgaga acagggacat ccagctggtg
    37921 tttggcaata tagttacaaa caccttcagc taggaggcta tcggttgtga tgatagcatc
    37981 aatttgtgga tcgtgcttga ataatcgctt gctaaattta tagccctttt cttccagaaa
    38041 ctcgtcggca aagtagatgc gattgttgtc agtggtaagt ttgtaatgtt taagcgcctg
    38101 ttcatagcct gttaaacggt ctttggtcac gaagagcttt ttacttcctc cgataaaggc
    38161 aatgcgtttg cagccttttt tgatgaaata ttcagtcgca tcaaaaccag cttgaacatt
    38221 gtcgttgtcg acaagtggga tgaaaggaga tagagattta cctaggataa ggaaggggaa
    38281 ctgttcttct gcgacgagtt ttacgagagg gtcttcttct tgggcataga gaaagattag
    38341 cccatctaca cgcttgccgt agaccatttg tgaaatagcg ttgagacgct ccttctcatc
    38401 tttccctgtt gctatctgaa tggcatagtg gttttcagat gcgacttgag agatgccacg
    38461 tagaaccgat ggaaagaaag gattctggta gaaggcgtct gagtcatcag gaagaactaa
    38521 tccgataacc tgagtatagc tgcttaccaa gctacgagcg ttgaggtttg ggtggtagtt
    38581 gagttccttc atagctttgc gaacgcgttt ttttgtttcg tcgctaatgg ttgatttatt
    38641 ttgaataaca cgggttacgg ttgaaggcga aacaccagca gccttggcca cgtctttaat
    38701 cgtaacgggc ataaaaatct cctatttatg gtaatttgga tcacggaaat gtgttttata
    38761 aaagatagtg accagataca gaacaaaaag aatattttgt acagtaatca gggttgtcat
    38821 attttggcca aataatccca aaataagtgt aatcagagtc ggcaatccta aacagttcaa
    38881 gataaagtga tagcactctt taaaggttct aaatgaaaag aggcgtgatt tcttagtgat
    38941 ataaaggaga agactagctc ctagagagac gataaagaaa ttcaaaccaa agaggaagct
    39001 cgcaccgaga actaggaaga ggctgatata gacacgattt tgttggtacc agtctttaga
    39061 aattgcttgg gtcaagctgt ctttgctttt gaaattctca gtctgaatgg ctcggtaaga
    39121 gatgcgggtc agttccttgc tttccttgct gatgactagc tcatttgtat cgaaatgcag
    39181 ttgcaagtcc ttaggtaatt ccttgatttg acttggacca atcacaacag aaggggtttg
    39241 actagctgtt ccagtataag ttaatgtgcc atcgacaatt gtagcatgtt cagagagatc
    39301 ctggacaacc tcatttgtca gaggttcata gacattatcg ataaaagttt ctagcggata
    39361 ggtctcctgg gagctgtttt ggatagcaat gggtaccata gacaagctga taaggaagat
    39421 actggtaaag agaagttgaa accagttgag ctcgaaacgt ttggacaggg gcttacgaaa
    39481 cccccaaata cttgaaaaat aggaaaatgg atatggaagc ataggtatct ttctaaaagg
    39541 tgttttctat atgagtatta ttatatagag aaatgcgctt tatttcaagt ctaggagaaa
    39601 aattgcttgc tacaaggata ttatttacag tgacaattgc taataatcaa tgaaaatcaa
    39661 agtgcaaact agccacaggt tgctcaaagc acaactttga ggttggagat aaagctgacg
    39721 tggtttgaag agattttcga agagtataaa atgaaaaagg gtggcgggga taaattatcc
    39781 cttgtcgcca ccacttgtaa gtcctgaaac aaagttcttt tgtagaaaga agaagagaat
    39841 acagattgga agggcgatga ggatagcacc tgctgagaag taggcaatct tcaagttttt
    39901 cgcattgtta acgaaggttt ggagacctac ggcaacagta aagtattctt tctcacgaag
    39961 caagaaacta gagaggatgt agtccccgaa aggtcccatg aaggcccaga gagcttgtac
    40021 ggcaaccatt gggcgaacaa gtggtagaac aatttgccag aagcggcgga agtgtcctgc
    40081 accgtctagt tttgcagatt cgtctaaaga cattggcact gtatcgaagt agcctttcat
    40141 gagccaagca ttcatcggga taccaccacc aacgtagagg aagatgagga accagttgtg
    40201 gttaagggcg ttcaacataa gcgccataac gaagaaggct gtcaaagcgg ccatagttgg
    40261 caccatttgg atgatcaaga agaagaccaa actttgttta cgagccaaga agttgtaacg
    40321 gctgtaagca taaccagcaa gtacgatgat acttgtttga acagccatgg taattaaggc
    40381 gataatcaaa gtgttgaggt accaagtacc gtacaaggtt tcagtgaaga ggcctttaaa
    40441 gttatcaaaa ttgaggtcga tattagtatc tagtttaaag gctgagacgt tacctgcttt
    40501 aaaggctgac ataatggtaa tcaacagtgg atagataatt acaattgata gaccaatcag
    40561 gtaaaggtaa gtaaggcttt gagtcagtct acgtttgagt ttaattgagt tattcatctt
    40621 agacgtcctc catatcaaat gcgtgtagtt tcttgaatgc gatcatagag attgagatga
    40681 caatgataga gataatcaag gtaacagctg ccgccattga gtattgagga gatgtacctg
    40741 ttgtcaaacg gtagatccat gagatcaaga tatcggttga accagctcca cctccgacac
    40801 taccaggtcc tccaccattg aagaggtaca tgatagagaa gttgttaaag ttgaaggtgt
    40861 attggctaat caaagtaggt gccgcaacag ccaaaatcat tgggaaagtg atgttgcgga
    40921 atttttgcca agcgttggca ccgtcaatat aagctgcttc gtaaaggtcg ttaggaatag
    40981 attgcaagat acccaaagtc aaaacgtaga tgtatgggaa tccgagccaa ccttgcatca
    41041 taatcaaggc aatcttagtc caagttgggt ctgttttcca aggaataaga gctccatcaa
    41101 ggaaaggaag gaatttagcc aagattggca atacttgagt gttgatagca ccgacactat
    41161 cgttaaacat gtttgagaat gtcaagatag tgatgaaggc tgggacagcc caaggaagaa
    41221 ggaaaataac accaaagata cgttttcctt tgataaatgg ttggttggca atgatagctg
    41281 tgaagatacc aattacgatt tgtaaagtag aagctgccaa agcccaaatg atagtccaag
    41341 aaagaacaga accaaaggca gaacggaagg tactcaagct ccaaatgttt gtaaagttgg
    41401 tcaaaccaac ccagtccaac aacttgtttg gtggcaagtg ttggaagtcg tagttggtaa
    41461 aggcgatcat caaggttacg ataactggga agataatcgc gaaggtcatg gcaacataag
    41521 atggaatgat caagaggtaa gggaagccat tttcataaat ccctttgatc atgtctttga
    41581 gtgtgcgtgg aactggaatt ccattgttaa tgcgttttgc aatcgtatgt gcatctttga
    41641 tatttgagaa ataaaagagt acataaacga ttacaaagat tagatggaag gcaccacgaa
    41701 tcagcataaa gagggaatta tcacgacctg gtttgtcacc aagagtgatg aggttgctca
    41761 attcaggggt tgcaagtgct aggaagtaaa ggacaaatac gatggttaca ccaaggaaga
    41821 taaaaccttt ggctttttgt ttattgtaaa tctgtcctaa cccaggaatg atagacagca
    41881 gggctgcttt actaggttgt tgcttttcca tattaactcc tttcatagga tactactttt
    41941 ttataagaaa gctaaattat ttgtgtctct attgataaat tcaaaggggg atttgatttc
    42001 cacccccctt gaacaaattt tttattcacc aaatttttgt ttgattgttt ctttgatcaa
    42061 tgttacagca tcgttagcag ctgttttagc atctttttga ccacttacag catcaaagag
    42121 catatttttc gctggatccc aaactgcaga catttgagag atgtttggca gtggttgagt
    42181 gttcttgaac tgtttgataa cagctgttgt caactcatcg tttttacctt cagcgtatga
    42241 acgagcctca gtattagctg ggatttcgtt agtcttatca tataatactt tttgttgttc
    42301 agttgcaaca aggaagtcta caaatttttg agaagcttca aggttcttaa cggcttgagg
    42361 aatgacccaa gctttaccac caccgaatgc agcatattct tttccatttg gaagagttgg
    42421 gatagttgca actccgtagt ttactttagc atctttaaag gcttgagctt tccaaggtcc
    42481 gtcgatgata gcagctgttt taccttcttg gaattgagtt tggattaagt ttccagcacc
    42541 ttctgtatct tgcatacctt taggccattt ttcgtaccaa gatttagcgt agttgatacc
    42601 tacgatagaa ccgtcgtttg caagaccgat gtctttagcg tctttaccgt tttggccaaa
    42661 gacgtaagca ccgttaccgg caagaagtcc atatgtatag tagaagtttg tccagtcagc
    42721 taggaaggca gtagttttac catcttcacc agcgaatgcg tatttgctat ctttagcaag
    42781 gttttccaag tcagcaaatg tttttggagc atctttcacc aagtctttgt tgtagtacat
    42841 aacaagtgac tcgataacgg caggagcacc gtaaacttta ccattagcag ctgttacaag
    42901 agatttagtt gtgtcgtctg ttttagcacc atcgctcaat ttcacttctg aaagttgtcc
    42961 gtcagaacca aggctaccta cacggtcgta tggagccatc ataacatcag ggacattacc
    43021 agattggttg tcaagagaaa gtttatcaag acctcctaga gcatcaccag ttttaagagt
    43081 gacttttact ccagcttctt tttcataagc tttagcaacc tcttcaatat agctcttata
    43141 tccctcgtct acatatacag tgagttcttt gacttcagat gaaccagaat cagcagactt
    43201 atcagcagtt ttgcttccgc aagctaccaa aagcaagcta gcaagtgtaa cagttccaag
    43261 caccgcagtg ctcttcataa atttagatga catagtgtat tcctcccaaa gaatagcaag
    43321 ttttattgat aaggaaacgc aaacgttttc ctttatgagc ttagtatagc acaaatagaa
    43381 aacggttgca agtatttttt gtaaaaattt taaaaaattt ttaagcttga tttgatagca
    43441 taattttgca ttttaataga agaaaagtat gaaatagata agaatacagt atttttaata
    43501 aaaatatatg gaatctgtct aaagagggaa accaggaggg gctacctccc tgtttctaat
    43561 ccctatctat tttctataga cgtttgtgct ttgttacata taaattcaag ctccctaagg
    43621 aggttttgta ctttgtagac tgtctcgtga gagtcaaact ttaggattag atagttttaa
    43681 gttatctttg ctaaaatgag ttagtctcct taaaaataat caaaaaagtt ttttaaaaac
    43741 gcttgcaatt atgcttgaaa aggagtatac ttataagtaa cgcaaacgtt tgcgtctgca
    43801 aaatacgcaa cgttccatta ttttaacaca cgaggtgcta ttatgaaaaa acgtcaaagt
    43861 ggtgtgttga tgcacatctc ttctcttcca ggagcttacg gaatcggatc atttggtcaa
    43921 agtgcttacg acttcgttga tttcttggtc cgtacaaaac aacgttactg gcaagtcctt
    43981 ccattaggag caactagtta cggggattct ccttaccaat ctttctcagc cttcgcagga
    44041 aacactcatt ttatcgattt agatatcttg gtggagcaag gtttgttgga agcaagtgac
    44101 cttgaaggag ttgactttgg tagcgatgcg tctgaagttg actatgctaa aatctactat
    44161 gcacgtcgtc ctcttttaga aaaagcggtg aaacgtttct ttgaagtcgg agatgttaaa
    44221 gattttgaga aatttgctca agacaaccaa tcatggcttg agctctttgc tgagtatatg
    44281 gctatcaaag agtattttga caatcttgct tggactgaat ggccagatgc agatgctcgt
    44341 gctcgtaaag cttcagcact tgaaagctat cgtgagcaat tggcagacaa gttggtttac
    44401 caccgtgtga ctcaatactt cttcttccaa caatggttga aattgaaagc ttacgctaac
    44461 gacaaccaca tcgaaatcgt tggggacatg ccaatctacg tagcggaaga ttcaagtgat
    44521 atgtgggcaa atccacatct cttcaaaaca gatgtcaatg gtaaggctac ttgtatcgca
    44581 ggatgcccac cagatgagtt ttctgtaact ggtcagcttt ggggtaatcc aatctatgac
    44641 tgggaagcaa tggacaaaga cggctacaaa tggtggattg aacgcttgcg tgaaagcttc
    44701 aaaatctacg atatcgttcg tatcgaccac ttccgtggct tcgaatctta ctgggaaatc
    44761 cctgctggtt ccgatacagc agcacctggt gagtgggtga aaggtccagg ctacaagctt
    44821 tttgcagccg ttaaggaaga acttggtgag ctaaacatca tcgcagaaga ccttggcttc
    44881 atgacagatg aagtgatcga attacgtgaa cgtactggct tcccaggaat gaagattctt
    44941 caatttgcct tcaacccaga agacgaaagc attgatagcc cacacttggc acctgctaac
    45001 tcagttatgt acacaggaac acacgataac aatacggttc ttggttggta ccgtaatgag
    45061 attgatgatg cgactcgtga gtacatggct cgttacacga accgtaaaga atacgaaaca
    45121 gtggtacacg ctatgcttcg tacagtattt tcatcagtta gctttatggc aattgcaact
    45181 atgcaagatt tactagaatt ggatgaggca gctcgtatga acttcccatc tacccttggt
    45241 ggaaactggt cttggcgtat gactgaagat caattgacac cagctgtcga ggaaggtttg
    45301 cttgacttga caacaattta tcgccgaatt aatgaaaatt tggtagattt aaagaaataa
    45361 gacaataatc aggagacaac taaacatgtt atcactacaa gaatttgtac aaaatcgtta
    45421 caataaaacc attgcagaat gtagcaatga agagctttac cttgctcttc ttaactacag
    45481 caagcttgca agcagccaaa aaccagtcaa cactggtaag aaaaaagttt actacatctc
    45541 agctgagttc ttgattggta aactcttgtc aaacaacttg attaaccttg gtctttacga
    45601 cgatgttaaa aaagaacttg cagctgcagg taaagacttg atcgaagttg aagaagttga
    45661 attggaacca tctcttggta atggtggttt gggacgtttg gctgcctgct ttatcgactc
    45721 aattgctact cttggtttga atggtgacgg tgttggtctt aactaccact ttggtctttt
    45781 ccaacaagtt cttaaaaaca accaacaaga aacaattcca aatgcatggt tgacagagca
    45841 aaactggttg gttcgctcaa gccgtagcta ccaagtacca tttgcagact ttactttgac
    45901 atcaactctt tacgatattg atgttactgg ttatgaaaca gcgactaaaa accgcttgcg
    45961 tttgtttgac ttggattcag ttgattcttc tattattaaa gatggtatca actttgacaa
    46021 gacagatatc gctcgcaact tgactctctt cctttaccca gatgatagtg accgtcaagg
    46081 tgaattgctc cgtatcttcc aacaatattt catggtttca aacggtgcgc aattgatcat
    46141 cgacgaagca atcgaaaaag gaagcaactt gcatgacctt gctgactacg cagttgtcca
    46201 aatcaacgat actcacccat caatggtgat tcctgaattg attcgtcttt tgactgcacg
    46261 tggtatcgag cttgacgaag caatctcaat tgttcgtagc atgactgcct acactaacca
    46321 cacaatcctt gctgaggcgc ttgaaaaatg gcctcttgaa ttcttgcaag aagtggttcc
    46381 tcacttggta ccaatcatcg aagaattgga ccgtcgtgtg aaggcagagt acaaagatcc
    46441 agctgttcaa atcatcgatg agagcggacg tgttcacatg gctcacatgg atatccacta
    46501 cggatacagt gttaacgggg ttgcagcact ccatactgaa atcttgaaaa attctgagtt
    46561 gaaagccttc tacgaccttt acccagaaaa gttcaacaac aaaacaaacg gtatcacttt
    46621 ccgtcgttgg cttatgcatg ctaacccaag attgtctcac tacttggatg agattcttgg
    46681 agatggttgg caccatgaag cagatgagct tgaaaaactt ttgtcttatg aagacaaagc
    46741 agctgtcaaa gaaaaattgg aaagcatcaa ggctcacaac aaacgtaaat tggctcgtca
    46801 cttgaaagaa caccaaggtg tggaaatcaa tccaaattct atctttgata tccaaatcaa
    46861 acgtcttcac gagtacaaac gccaacaaat gaacgctttg tacgtgatcc acaaatacct
    46921 tgacatcaaa gctggtaaca tccctgctcg tccaatcaca atcttctttg gtggtaaagc
    46981 agctccagcc tacacaatcg ctcaagacat tatccattta atcctttgca tgtcagaagt
    47041 tattgctaac gatccagcag tagctccaca cttgcaagta gttatggttg aaaactacaa
    47101 cgttactgca gcaagtttcc ttatcccagc atgtgatatc tcagaacaaa tctcacttgc
    47161 ttctaaagaa gcttcaggta ctggtaacat gaaattcatg ttgaacggag ctttgactct
    47221 tggtactatg gacggagcta acgtggaaat cgctgagttg gttggtgacg aaaacatcta
    47281 catctttggt gaagattcag aaactgttat cgacctttac gcaaaagcag catataaatc
    47341 aagcgaattc tacgctcgtg aagctatcaa accattggtt gacttcatcg ttagtgatgc
    47401 agttcttgca gctggaaaca aagagcgctt ggaacgtctt tacaatgaat tgatcaacaa
    47461 agactggttc atgactcttc ttgatttgga agactacatc aaagtcaaag agcaaatgct
    47521 tgctgactac gaagaccgtg acgcatggtt ggataaagtc atcgttaaca tttctaaagc
    47581 aggattcttc tcatctgacc gtacaatcgc tcagtataat gaagacatct ggcacttgaa
    47641 ctaatactct tcgaaaatct cttcaaacca cgtcagcttt atctgcaacc tcaaagcggt
    47701 gctttgagca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    47761 tacaaattta tactaataca ttttgtaaaa aagtgagttt cgattgaaat tcgctttttt
    47821 aaatgctgtg gatttgggtc aatcttgtct aaaaataggg aaatcctaga tacagtgaag
    47881 gctttaaatg ctggttttta ctgtcttcag ccttatattt tttcgtagtt ggttacctca
    47941 tatctcttgt attcgcttac ataaagtatt ataatataat tgtaggaaag aaggtgtttt
    48001 tatgatatac acacttaaat tggtgttgtt tattaccttt cttgtaataa gcttgttacc
    48061 tgataagatt tttggaaaaa ataaaaaaat ttggaaaata gtttttgcaa tattgacggc
    48121 agtggcagca ttgtcattta tgtactaagt tattttaaga atgtagggaa ataaacccta
    48181 cattcttttt agttttttct gttttctaaa ttctatttat ccaagcgctt caacatttct
    48241 tgcttcttcg cttcaagttc tgcacgcttt tcttcgattt cggcatgttt tttctcgagt
    48301 tcagaacaac ttgcaccatt gctaaattct tttcgccatc aggagatagg gtgagtcgac
    48361 atgtctatta ctcacccaaa gcagtcctac aaagcaggaa ttttctgtta cttttttgga
    48421 aatagtaacg tttatacagc tttggcactt cgtatcaaag cgccaaacac actccgaggg
    48481 atttacagaa agcagaaaag gaatgatctg gtataagatc attccttttc tctctttttc
    48541 tttaagtaat tatatacaat gtacgacgaa gtcgtcattg caatgctgat ccaccaccta
    48601 aagggaactt taaacaacat tgataagata aagaatataa acaacgaaaa tacgttatac
    48661 ccaattaatt ttattgtata tctcatgatt aaaagttaat ccttccgttg ttaggaatgg
    48721 catcattttt atcccataat tgtgctaaat aagtccccgg tgataataaa ttcatagcga
    48781 attctaaagc aacatcattt acaaaccaac tacctagata tctagaaatt gctgaacgaa
    48841 tagcactttt tgctgcatgt tttcctttta ctttaattag atttgcaagg cctgcagtag
    48901 ttcctcctaa tgctaaagct attgcagtat ctaatagagc acccatttga ttaactgtaa
    48961 taccttgcca agctgctcta aatggagagt atgtaggtgg gattgtataa tcgccttgta
    49021 attgtcggtt aattacttct ttgatccatt gttgtgagac gtctggatga aaagattgga
    49081 tttcgtttgc aagtgtattg atttgttctt ctgttagaga agtgacaggt tgaagttcca
    49141 tatttgtttc aatttgtgat acttgttcag aagcgtatac agctgaaaca cttggaatcg
    49201 ctgatacaat taacacaatt gacgtcaaaa aaaccgaaat aaatttcatt aatttgttca
    49261 tgagcttttc tcctttttat ttgtatctgc ttacatttta tcatatactg ttattatagt
    49321 caaaaaaata tttttcaaaa tataaatgga cggatttatt ttggatttta tttgttattt
    49381 tgacctgcct ctatattggt aaccatgatt tgtttactct caatcatcaa gaattctctt
    49441 ttcgtggtag cgtttggggt ctggtactgg ccttatatca cttactattc attgataagt
    49501 ttgttatatc gaatcgaaaa taaagattag agctatgctt gactgtgtac ttttaggatt
    49561 gattttggag gaagattttg tctctattat ttattatttt aaatttattt attttgtata
    49621 agatctattc tttgaggcgg gaaaaatcga aatacttgat ttatacggcc tatatcatat
    49681 ttggggtaaa tgtagtatat ggtattcaat ggttattaaa agaactgatt tcaactattt
    49741 ccccttaatg tgtatggaaa ctataacaaa acgcataaga ttaaggtttg tgtacctgtt
    49801 cttatgcgtt tttataatat tgaagatttt cggtaagttt tatacctttg ggaagtctag
    49861 tttagaatgc tttcccaacc aaaatctctg cttcgatggt aatctctgtc agttggctcc
    49921 agtcaatctt gctctggtca acgtgaaaga ggagaggagt catactgagt agggcttgga
    49981 gttgttctgc tgtgatagtc ttagtcagag aggcagtttg actagatagg atggtaaagt
    50041 gttcctggaa atgctccttg atatcttggt tagaatactc cttgtttgtc agctggtcct
    50101 gtactctttg acggatttct ttgaggtgat tttcagttgg gataaccttt atcaagatac
    50161 cgtctttgga taaaacgcga cgaaattctc catagttggc aggtgagaag atatcaagca
    50221 gaatatccat gttagcgtct tttataggaa ggcgtgccaa gtcgccaacg aaccaattga
    50281 ctgcccagtt gggttcactt ttagcagcga tttggactga atctttggag atgtcaaagg
    50341 catagaaagt tttttcagag tgactttctt gtagtttgcg agaatagaat ccttcaccac
    50401 aaccgatatc caaaattgtt gtggtagttt ttgagcttgc aagcaagtca gatacagcat
    50461 ctaagatagc ttggtaaaag ccggcttcta ggatttgttg acggttttga aaattttcct
    50521 tgtcatagtt agcagattgc ttgatttgag gtgctagatt gacatagcca aatttcgcca
    50581 agtcaaaaga atgacggttg cagcacttga aattagtttc taacagagtc agattttctt
    50641 gacagatagg acaggcaaag gcagtcgcag aagcaaaacg ctgaagtttg ggtttgagat
    50701 ttgtattcat agtttaagtg tatcaaaaga ggcaaatgaa agcaacttta ggaataagta
    50761 gatgggagat tcagtagaaa taaaactaat tctccaattt atagaatgaa attgctttta
    50821 tatctaaatt gctatataat aatgataagg aggaaataag tatgttaaaa gaagtattaa
    50881 ccgttgcaaa agttgcgaaa aaatcttcat tatttttggg tggtgtcgca tttggtaccc
    50941 ttggtttgaa aatcttagca agtaaggaag ctaaaaaagg ttattctaaa gctttggcta
    51001 aggcttacaa gttgaaagac gagctagatg catctgtttc tgttgtgaag caacatggag
    51061 acgatgtctt gcaagatgcc aaatatttgt acgagcaaga gaaaaaagaa gagcaattag
    51121 atagccttat aggtgaataa tatgtctttt aaagtgctac atagaggata ccaacatatc
    51181 cgactatcat cttctttttc acttaccttg gatattcaag actatcttcg ttccttggcg
    51241 agagatgaaa aggggattga gtctatccag ttttacatgg atcaacagca ctttactcta
    51301 cgcataaaag aaggcttttc tgtattagat aatgcagaag cctttttaaa aagaattgat
    51361 aaagggaaag tttctgagtt gatgactctt cccattcgta gagaagagag tgcttattct
    51421 attgtttcag gtgcagcggt taagcgtgta ctttttcgta gttttgtgcc gtatcctatt
    51481 cgctatatat ggacttgtta tcaggctttg ggttatatta gagaagccta tcaaacacta
    51541 gcgcgtaagg aactaacgat ggaagtcttg gactgttcgg ctattttatt gtccttgttt
    51601 atgaaccaat ccaagacagc tagcaatatc atgtttatgc ttgatttggg gaatcattta
    51661 gatcagtggt ccttgaaaaa aactgcaaca gatttagaac agagtcttct tgcaaaagag
    51721 agcgatgtat tcctagtaca gggcgatacg gttgttagta tcaagagttc cgatgttcaa
    51781 ataggagatg tcttgatctt atctcaagga aatgaaattc tgtttgatgg acaagtagtt
    51841 tcaggtttag gtatggtcaa cgaaagttcc ttgacaggag agagttttcc agttgaaaaa
    51901 agagagtctg atttggtttg tgcaaataca gtattagaaa ctggagagtt acgcattcgt
    51961 gtaacagata atcagatgaa cagccgtatt ttacagctga ttgagttgat gaagaaatct
    52021 gaagaaaaca agaaaacgaa acaacgctat ttcatcaaga tggcggataa agtcgtcaaa
    52081 tataatttct tgggggctgg gctgacttac ctattgacag gttctttttc taaggctatt
    52141 tctttcctat tggtcgattt ctcctgcgct ttgaaaatct ctactcctgt agcttatttg
    52201 acagttatca aggaagggtt gaaccgtgaa atggtgatta aggatggaga tgttctggag
    52261 aaatatctgg aagttgatac tttcttgttt gataagacag gaacaatcac aactagttat
    52321 cctatagttg aaaaggtgtt accttttgga gactatagtg aggaagatat tctcagaatc
    52381 agtgcctgtc ttgaggaaca catttatcat cctattgcta atgccatcgt caagcaagct
    52441 gagatagagg gaattgaaca tgaggaaatg catgggaaac tccaatatat cgcaagcaag
    52501 gggatcaaat ctcatataga tggccaacca gttcttattg ggaattatgt cttgatgcag
    52561 gatgagcaga ttcatatcag ttcagaacaa aatgctttaa ttgaagagta caagagtcac
    52621 tacaatctct tattcttggc ttatcaaaat gaattgattg gaatgttctg cattcatact
    52681 cctttgagaa aagaagcaaa aacagccttg gataaactta aggcacaggg gaaaaaattg
    52741 attctggcaa caggagacac cttgattagg acagaggaat tagtcaaaga tttgcccttt
    52801 gatcaggtct atacagactt gaaacctgat gggaaatttg agttagtaga gaaactgcag
    52861 aaagcaggtc acactatttt gatggttgga gatggattga atgactcagc ggctttaact
    52921 ctatcagata tcggtgtggt gatgaatgag agtgcagata tttctaagca gatgagtgat
    52981 atcttattgt tagataatcg tttggatttc ttccaagagt tggattcgtt atcatcatct
    53041 ttgcaaacac tcatcaagaa aaatattcag gataccgttg tcgtaaatag tagtttgatt
    53101 ggctttggct tatttaattg gttcagtcct tcaaatctct ctatcttaca taatctaaca
    53161 accttgcgca ttgtcctgcg tagcctgtct attaaaaata gatagatgag agttattaac
    53221 agcaaaaagg agttaccttt ctcgaggtta actcctttgt ttatagataa atgttgaata
    53281 gtttagtaag tcaatacaaa gtattttttc ttcccacgac ggataacagt cagttcattt
    53341 tctaacttat cagcgtcact caagacatag tcaaggtctt ggatgcggtc gccgtttacg
    53401 tagatggctc cgttttggac gtcttcacgg gcttggcgtt ttgagttaac tataccagat
    53461 gagacgagca gttccacgat attgttgttt tcgtctgcct gtacttggta gtttggcaca
    53521 ccacgaagtc cttgtttgag ctctttgaca gaaaggtttt tgatgtttcc tgcaaagagt
    53581 tgctcagtga tgttaagtgc ttctttgtag gcttcttctc cgtgaacaag tgtaacaact
    53641 tcacgagcca agactttttg agccaagcgt tcgtgtggcg ctgcttcaaa ttgtttacga
    53701 atatcttcaa tctcatcaag tgacaagaaa gtaaagattt tcaagaagcg aacagcgtca
    53761 gcgtccatca cgttcatcca gaattggtac atttcgtatg gagaagtctt ttcgggattg
    53821 agccagacgg catttccttc tgatttacca aattttttac cagttgcatc tgtgattagt
    53881 ggaacagtga taacgtgacc agtcttgtcc gccttacgac gaagcaattc ggtaccagct
    53941 gtcatatttc cccactggtc agaaccaccg atttgaagag tgacattatg gtcttggtta
    54001 aggacgaaga agtcgtaccc ttgcatgatt tggtaagcga actcagtgta agaaattcct
    54061 gtttcgatcc gttttttaac agattcctta ctcatcatgt agttgaccgt gaagtatttt
    54121 ccaatgtcac ggaggaagtc aatgaagctg atgctgccaa accagtcgta gttgttgacc
    54181 atgacagcct tgttttcgcc attttcaaag tcaagaaaac gagaaagttg tccttggata
    54241 gacttgaccc agccatctac tgtgtctttt gtttggagac tacgttcagc atctttgaag
    54301 gacggatctc cgatgagacc tgtagcaccg ccaacgagcg cataaggttt gtgacctgct
    54361 agttgcaagc gacgacttgt caagattgcg acaaggtggc ctaggtgaag gctgtcagca
    54421 gttggatcgt agccagtata ataagaaact tgaccttctt ctagggcttt acgcaaagct
    54481 tcttcatcag tcgtttgaaa tatcaaacca cgctctttta gctcatcaaa aatgtgcatg
    54541 tgtcttttct cctttttaaa attattgttt ctacctattg tatcacaaac ttgggcaata
    54601 gcctagcaga atagggaaga aagtggctat tttattgaaa atttcccttt tgtggtataa
    54661 tagatagagt gaggaaatcc atgcaaaatc aattaaatga attaaaacga aaaatgctgg
    54721 aatttttcca gcaaaaacaa aaaaataaaa aatcagctag acctggcaag aaaggttcaa
    54781 gtaccaaaaa atctaaaacc ttagataagt cagccatttt cccagctatt ttactgagta
    54841 taaaagcctt atttaactta ctctttgtac tcggttttct aggaggaatg ttgggagttg
    54901 ggattgcttt ggggtacgga gtggccttat ttgacaaggt tcgggtgcct cagacagaag
    54961 aattggtgaa tcaggtcaag gacatctctt ctatttcaga gattacctat tcggacggga
    55021 cggtgattgc ttccatagag agtgatttgt tgcgcacttc tatctcatct gagcaaattt
    55081 cggaaaatct gaagaaggct atcattgcga cagaagatga acactttaaa gaacataagg
    55141 gtgtagtacc caaggcggtg attcgtgcga ccttggggaa atttgtaggt ttgggttcct
    55201 ctagtggggg ttcaaccttg acccagcaac taattaaaca gcaggtggtt ggggatgcgc
    55261 cgaccttggc tcgtaaggcg gcagagattg tggatgctct tgccttggaa cgcgccatga
    55321 ataaagatga gattttaacg acctatctca atgtggctcc ctttggccga aataataagg
    55381 gacagaatat tgcaggggct cggcaagcag ctgagggaat tttcggtgta gatgccagtc
    55441 agttgactgt tcctcaagca gcatttttag caggacttcc acagagtccc attacttact
    55501 ctccttatga aaatactggg gagttgaaga gtgatgaaga cctagaaatt ggcttaagac
    55561 gggctaaggc agttctttac agtatgtatc gtacaggtgc attaagcaaa gacgagtatt
    55621 ctcagtacaa ggattatgac cttaaacagg actttttacc atcgggcacg gttacaggaa
    55681 tttcacgaga ctatttatac tttacaactt tggcagaagc tcaagaacgt atgtatgact
    55741 atctagctca gagagacaat gtctccgcta aggagttgaa aaatgaggca actcagaagt
    55801 tttatcgaga tttggcagcc aaggaaattg aaaatggtgg ttataagatt actactacca
    55861 tagatcagaa aattcattct gccatgcaaa gtgcggttgc tgattatggc tatcttttag
    55921 acgatggaac aggtcgtgta gaagtaggga atgtcttgat ggacaaccaa acaggtgcta
    55981 ttctaggctt tgtaggtggt cgtaattatc aagaaaatca aaataatcat gcctttgata
    56041 ccaaacgttc gccagcttct actaccaagc ccttgctggc ctacggtatt gctattgacc
    56101 agggcttgat gggaagtgaa acgattctat ctaactatcc aacaaacttt gctaatggca
    56161 atccgattat gtatgctaat agcaagggaa caggaatgat gaccttggga gaagctctga
    56221 actattcatg gaatatccct gcttactgga cctatcgtat gctccgtgaa aagggtgttg
    56281 atgtcaaggg ttatatggaa aagatgggtt acgagattcc tgagtacggt attgagagct
    56341 tgccaatggg tggtggtatt gaagtcacag ttgcccagca taccaatggc tatcagacct
    56401 tagctaataa tggagtttat catcagaagc atgtgatttc aaagattgaa gcagcagatg
    56461 gtagagtggt gtatgagtat caggataaac cgattcaagt ctattcaaaa gctactgcga
    56521 cgattatgca gggattgcta cgagaagttc tatcttctcg tgtgacaaca accttcaagt
    56581 ctaacctgac ttctttaaat cctactctgg ctaatgcaga ttggattggg aagactggta
    56641 caaccaacca agacgaaaat atgtggctca tgctttcgac acctagatta accctaggtg
    56701 gctggattgg gcatgatgat aatcattcat tgtcacgtag agcaggttat tctaataact
    56761 ctaattacat ggctcatctg gtaaatgcga ttcagcaagc ttccccaagc atttggggga
    56821 acgagcgctt tgctttagat cctagtgtag tgaaatcgga agtcttgaaa tcaacaggtc
    56881 aaaaaccagg gaaggtttct gttgaaggaa aagaagtaga ggtcacaggt tcgactgtta
    56941 ccagctattg ggctaataag tcaggagcgt cagcgacaag ttatcgcttt gctattggcg
    57001 gaagtgatgc ggattatcag aatgcttggt ctagtattgt ggggagtcta ccaactccat
    57061 ccagctccag cagttcaagt agtagttcta gcgatagcag taactcaagt actacacgac
    57121 cttcttcttc aagggcgaga cgataattct ctaaatgaag tggccaatca atggattgcc
    57181 acttttttcc tttcgtgtta caataagggt atgaatcagt atcagaaaaa gattgttaac
    57241 ggaaaaattt attcgctcct atccggctta atatggggaa tctgtggaat tttaggagag
    57301 tacttcttta ctcattatca ggtgtcttcg ggctggatta cctctatgcg tttgacactg
    57361 gcagggagta ttgtactcat ttggtctgca atacaattaa aatcgcaagt gctagatatt
    57421 tggcgagaca agaaaaatta cctgcccttt ttagcctatg ctattttggg gattttttca
    57481 gtccagtatt ttttctatct ctgtgtagaa tactcaaatg ctacgacagc aactatttta
    57541 cagtttatta gccctgtctt tatcctcttt tacaatcgct tggtttatca aaaacgagcg
    57601 tcaaaaagcg ctgttttcta tgttttggtt gccatgctgg gtgtttgctt gatggcgaca
    57661 aagggagatc tctctcagtt atccatgacg ccgctagctc ttataacagg tttgctgagt
    57721 gccatgggtg ttatgtttaa tgttatcttg ccccaacctt ttgctaagcg ttatggtttt
    57781 gttcctacgg ttgggtgggg gatgattttg gcaggtttgt ttagcaatgt cctctcgccg
    57841 gtttatcagc tttcctttac tcttgatatt tggagtatct tgatttgcct cattatcgct
    57901 ttctttggaa cggcttttgc ttttttcatt tccatgaagg ctgtgtcctt ggtttctcct
    57961 ttggtggttg ccgttatcag tgccagtgaa cctctctctt ctgctctctt gagtgttttg
    58021 ttcttaggat tagtagtgga ttggtccctc cttctagcta tagtcttgat tattttaccc
    58081 atgatatttt tgtctataga agaagcgaaa gaaagtagat aaaaagtctt ttcttaattc
    58141 taaaagtgtg ctatactaga atagtcaata aaacacgggg agatagttgt gaagagtgtt
    58201 tttaggttgt atcggtaggg gcttgctttt accgacagca cgttttatct cacaacccta
    58261 aaaaatcata cctaaaaaca gacaaaaagg tttcaaattt gaggcctttt ttggtagaat
    58321 aggtatcatt ataacgaacc aggaggcacc tatgactgct acaaaaatga acgctcaaga
    58381 aattatccaa tttatcgcca atgctgaaaa gaaaaccagt gtcaaagtaa cctttgaggg
    58441 gcaactcgca actgctgtgc ctagctctgt tgtcaaacta ggaaatgtcc tattcggaga
    58501 ctggaaggac gtggctccgc ttcttgaagg tttggtagaa aatcaagatt atgttgtcga
    58561 gcaagatgct cgtaattctg cagttccttt gctagataag cgtgctatca acgctcgtat
    58621 cgagccaggt gctattatcc gtgaccaggt ggaaattggt gacaatgctg ttatcatgat
    58681 gggagctgtt atcaatatcg gtgctgaaat cggtgctgga accatgattg acatgggtgc
    58741 catccttggt ggccgtgcca tcgttggaaa aaatagccac gttggtgcag gtgcagtttt
    58801 ggcaggtgtg attgagccag ctagtgctga accagtccgt gtcggagaca atgttcttat
    58861 cggggctaat gcagtggtta tcgaaggagt ccaaatcggt agtggttcag ttgtcgctgc
    58921 aggagctatc gttacccaag atgtcccaga aaacgtggta gtagcaggtg ttccagctcg
    58981 tatcatcaaa gaaattgatg cccaaaccca acaaaaaaca gcgctagagg atgcgcttcg
    59041 taccttgtaa ttgtaaaagt aaaaaagagg cggaaccctt tttccagcct ctttctgcta
    59101 tatcggagga cagatagatg ttagatttga ttcagactag acgagcttta caccagattc
    59161 cagagattgg cttggaggag ttcaagactc aggcttattt gctggatgtg attgagaaat
    59221 tgactacggg caaggatttt gttcaaattc gtacttggcg gacagggatt ttggcctacc
    59281 tgcagggaag tcagccggag cgaaccattg gttggcggac agatattgat ggcctgccta
    59341 tcgtcgaaca aacaggtcta ccttttactt ctcaacacca aggtcgcatg catgcctgtg
    59401 gtcatgattt tcatatgacc attgccttag gctgtcttga gcgcgccctt gaggagcaac
    59461 ccaagaataa tctgctcttt ctatttcagc ctgctgaaga aaatgaagct ggtggtatgc
    59521 tcatgtatga ggacggtgct tttggagatt ggttgccaga tcaattctat ggtctccatg
    59581 ttcgtccaga tttgaaagtc ggccagattg cgactaatac tcatacactc tttgcaggaa
    59641 cttgcgaggt gaagatccgt ttcaaaggta aaggtggcca cgcagctttt cctcatgaag
    59701 ccaatgacgc cttggtggcg gctagttact ttgtgaccca agtgcagtca gttgttagcc
    59761 gcaatgtcaa cccaatcgag ggagcagtgg tgaccttcgg cgtttttcaa gctggaacca
    59821 ccaacaatgt catcacagac acagcttttt tacatggaac tattcgtgcc ttgacacagg
    59881 acatgagtct cttggtgcaa aagagggtaa aaacagttgc agaaggggtt gcagctgcct
    59941 ttgatatgga agtcgaagtg gaactcaaac aaggtggata cctacctgtt gagaacaatc
    60001 cagccttggc gcgtgaactg atggacttct ttgacgagaa agacggaatc gagttgattg
    60061 atatcgaacc tgctatgaca ggcgaggact ttggttatct cctttcaaag gttgatggcg
    60121 tgatgttttg gctaggtatc gatagtccct acgctcttca tcaccctcaa atgagtccta
    60181 aggaagaagt cttagctatt ggggtggctg cggtgtctag tttcctgaaa aagaaggcag
    60241 cagaatagag ggcttgtcta tgaaatcgga attacgcaag caagtcttgc atgaaatgaa
    60301 ggctatatct caagagcaaa aacaggctat agaccaagct ttaaccgagc gaattttaca
    60361 acaccccttt tatcaagaag ccaaggtcat cgcaacctac ctctcttttt ctcatgagtt
    60421 tcaaacgcgg gaactgattg agcaggcgct gaaggacggc aagaaggttt tgacacctaa
    60481 gacctatccc aaggggcgca tggattttgt ggtctatgat ccgcaacagt tggtaaaaac
    60541 ttcctttgga ttactggagc cacagggaga tttggaagtt gtggatgttt caaagattga
    60601 tttgattcat gttcctggtc tggcttttac gacaaaagga tatcggatag gatacggtgg
    60661 aggctattat gaccgctatc tggaacattt ttctggtcgt gctttgagta cgatatatcc
    60721 ttgtcaaatt caggacttta tacctgaaaa ccatgatatt cctgttcagg aggtattaat
    60781 tgatgaagga aatctttgat agacgttacc ctgtgacgag tttcttcctc ttagtgacgg
    60841 ccttggtatt tttactaatg ttggtcactg caggcggaaa ctttgacagg gcagatacat
    60901 tatttcgatt tggagccatg tatgggtcag ctattcgcct ctttcccgag caggtttggc
    60961 gtctcttgtc tgccattttt gttcatattg ggtgggaaca tttcattgtt aatatgcttt
    61021 cactttatta tcttggaagg caggtagagg agattttcgg ttctaagcag tttttctttc
    61081 tctatctttt atcaggaatg atgggcaatc tctttgtttt tgtatttagt cctaaatcct
    61141 tagcagcagg cgcctctacc tctctttatg ggctatttgc cgcgattatt gttcttcgct
    61201 atgcaactcg caatccttat atccaacagc tagggcaatc ctatctgaca ctttttgtgg
    61261 ttaacattat tggaagtgtt ctgattccag gaatcagcct agcaggccat atcggtggtg
    61321 cagttggtgg cgcatttcta gcagttatct ttccagttag aggagaaaaa cggatgtata
    61381 ataccagcca gagattagga gcggtagtct tgttcgtagg actcgccatt ttgcttttct
    61441 acaagggaat gggaatgtga cgaagttgaa agaaaatttg tgtaatgaaa aaagataagg
    61501 cattttttga accttatctt tttattttat tttattcctt ctcagtcaat tcttttccaa
    61561 gttggatgag gtaattcttc aaatcatctt tgacttgtgg gtgtttgagg gcgtagtcga
    61621 tggatgtttt catgaagcca aacttgtctc cgacatcgta acgagcccca ttgaactcac
    61681 gagcaaatac acgttgtgtt ttattgaggg tgtcgattgc atctgtcagc tgaatttcat
    61741 ttcctgcacc tggagcttgg ttttcgagga tttggaaaat ttcaggcgtg aggaggtagc
    61801 gtccgataat agcaaggtcg ctaggagcgt cctctggagc tggtttttca acaaaggttt
    61861 caacactgta aagaccattt tttccttcgc cttgcggagc aataaccccg taagcagata
    61921 cttcgtcatg agggactggc atgacagcga tagtagacgc gtgggtacgc tcgtagtcat
    61981 ccatgagttg tttggtaagt ggaacagcct tttcgtctgt gatatccatc aagtcatcac
    62041 caagcataac gacaaaaggt tcatttccga cgaaagcctt ggcttgcaaa acagcatctc
    62101 cgagaccgcg tggatgagtt tggcggataa aatgcagacg catgtcagtt gttttatcaa
    62161 ctagcttcaa aagatctgtt ttcccttttt ctttgaggtt atattccaat tcgaagtttg
    62221 aatcaaagtg gtcctcaata gaacgttttg atttaccagt gacaactaga atatcttcaa
    62281 tacctgattt gagagcttct tccacgataa actggatagt tggtttgtct acgattggca
    62341 acatttcttt ggcaagggcc ttggttgctg gtaaaaatcg agttcctagt ccagcagcag
    62401 ggataactgc ctttctaact tttgatgtca taaaaatcct ttctatagag ggttaagacc
    62461 actcattttc tgctttaaat tcattgttca tgatgtcata aatggcatct ttgatattgg
    62521 ttccgtgata aataacttgg taaatagcct gtgtaatggg catatagact ccaagttctt
    62581 gggctagttc ataggctgct cgagtcgttg aaattccttc gattaccatg cccatattag
    62641 cttctatatc agctagggat tctcctcgtc cgagagcatc tccagctctc cagttacgag
    62701 agtggatgga agttcccgtt acgatcaaat ctcccacacc agataagccg ctataggtca
    62761 atggactggc cccgagtgct acccctaggc gggtgatttc tgctaaacct cgagcgatga
    62821 tggctgcctt agcattatca ccaaatccaa gaccatgtaa agctccagca ccgacagcaa
    62881 taatattttt aagagcacca gcagtttcaa ccccgataac atccgtattg gtataaagtc
    62941 ggaagtagtg attactaaat agcttctgaa cgtattgagc tgtttgtaaa tctttagaag
    63001 cagcagttat taaagttagg tcacgcacaa tggtctcttc tgcatgacta ggccctgaaa
    63061 caacgacgat atcactacgg agatgttcag gaatttcttc ttcaagaatg gttgataatc
    63121 gtttatggct atcaggttct aatccctttg atgcgtgcat gatgataacc ttatggtcca
    63181 aggtttgtgc aacttgttgg gcaacaagtc gtgtcacttt tgttgggaca acaaacaaaa
    63241 tcgcatccac atctttcaat gtttctgcta agtcggtgta ggcaatgata ttttcgtcta
    63301 gaacgacatc tttaaagtag tgcttattag tatggtgtgt attaatttca ttgatttgct
    63361 cgggaagatt tccccaaata cgtacctcgt gtccattgtc atttaagact tgtgaaaggg
    63421 cggttcccca agaaccaggc cccaagacgg cgacggtttg tttttccatg atttcctcct
    63481 tgatagagtt ctttctctta ttctatcata ttctagggga ttttgcactt gcattactgg
    63541 ggtatggtgg aaaaatacac aaaaaccgag acgaagggat aaactcttag tctttagtta
    63601 aagtgagaag aaatctgata gatagtttga ttcagtatat gcttataata gaggtaaaca
    63661 actcaggagg ttcttgtagg ttgcgagagt ttggcgaaaa aattaaaaga ttacgtttgg
    63721 ctaaaaaaat cagtcgttca gaattttgtg gtgatgagtc tgaattaagt atccgtcaat
    63781 taattagaat tgaaaatgga gaatccagac caatactaac aaagttaaaa tatattgctg
    63841 aacgtttggg ggttgaagat tacaagttga tgccaagtta tatagagttg gataaggaat
    63901 acctagaatt gaagtatttc ttgatgagga ctcctacata cgaagatgaa actatcgccc
    63961 aaaagaaaga gagtgttttt gataagattt ttgaagagta ttatgatagg ctacctgagg
    64021 aagaaagatt tatcatccca aattattcat atctggcact aacgaactat acagttcaaa
    64081 aattaccaga aaagctagtt gaaatactgt ccttctggtg attttgctta atttctgatg
    64141 ttcgagacat gattgaggag atttgtcttg attttttcct aaaaaagggc agactcctcc
    64201 cttggtttga tgctcgattt ttaaaataag gtgacttatt ctgttaggca tgttttcccc
    64261 tgccctctag ctttatatgg aacagggagt atcagattta tctggcagat tgtatcaaat
    64321 aaggcttgaa actgttttga ataggcgtat agacttgaga atttgagaat atgtcgtcta
    64381 gcagtagaga catattttcc ggcaatatga aggaagagac gtcgaaaacg cttgatagtc
    64441 aaggccttta cttcatcacc agctagctgc tttaaaaaga ggtagagatt ataagccaga
    64501 cagcccatca tcatacgtac ttcattctta atcatggtcg aactatctgt cttatcccca
    64561 aagaatcctg ctttcctttc tttgataaag ttttcagcat tccctcgttc acgatagaat
    64621 tgaaacagct cctcactatc tacactgctt aaattggtca aatgaacttt tttacaacca
    64681 taaaaaagag cacttaatcg tactcttctc ttttaaggat tagttgaatt aattcaaatc
    64741 cactagttct cctgtttcta ggtagactag gcgttcacaa atgttagcaa tgtaatcagc
    64801 gaagcgttcc agatgcccta tgatataaag gtattgtgtt ccattgggaa ttgaggtttc
    64861 ttggtctttc ataagtccaa tgatttcctt tgataaggca taataatatt ggtcaatctg
    64921 ttcatctttt tgagcaatac taatagcttt tgaggcttgg tgcaaaggaa aggcaaccaa
    64981 taaatcggct agcatgctga gggataattt acccatttgg tgtaactgtt cttcgtcagg
    65041 ggctagttga ttttctttta gttgcaaaac agctttagca atgcctgcca tatggtctcc
    65101 catacgttca aggtctgaac aagaagacat gatgctaatc acaaatcgaa ggtcagacac
    65161 ttgtggctgc tgcaaggcca acaaacgggc acaggtcaat tcgatagcgc tttgaccttg
    65221 gttgatagca tgatccttat tgataattag ctctgccatc tccttgtctt tggaggctaa
    65281 ggccagtaag gcttttgaag ctgtttcaag gacaagttgc cctagtccta aaaaggattg
    65341 ttctaattca tgcaattcta agtcaaattg atttctcata ggtttttcct tccttatccg
    65401 aaccgtcctg aaatatagtc ttctgtgcgc tgatcttttg gattggtaaa cacgtcaacg
    65461 gtatctccaa attcgcaaat ttctcctgtt aagaaaaaag cagttttatc tgaaatacgt
    65521 gaagcttgtt gcatgttatg ggtaacaatg ataatcgtat aatccttttt tagttgctga
    65581 atgaggtctt caatttttaa agtggagata gggtctaagg ctgaagtcgg ctcatccatt
    65641 aacagaacat caggttctac tgctaaagct cgcgcaatgc aaaggcgttg ctgctgaccg
    65701 cctgataagg acatggcact ctttttaaga ttatctttga cttcgtccca aatggctgcc
    65761 ccttttaaag atttttccac taaggcatct aattgttttt tgtctcgaat accatgtgtc
    65821 cttgggccat aagccacgtt atcatagata gacatggcaa agggattagg ctgttgaaaa
    65881 accatcccta cacgcttgcg tagctgatta aggttgaatt tgctactata aatatcttgc
    65941 tcatctaaga ggacttggcc ttcaatatgg caagaaggaa ccaaatcgtt catccgatta
    66001 agggttttta gaaaagttga tttgccacaa ccagatgggc ctatcaaggc agtaatctgt
    66061 ctttctggta attgaatcga aatatttttt aaggcttgaa aatccccgta aaataagtct
    66121 aggtgtctga ctgaaaatgt tcccatacta ggaagctcct ttcacaagtt tccgagataa
    66181 taagcttgat agagtattta tcattaaaac agtaataatt aaaatcacgc cggtagcata
    66241 ggcttcattg acatgtagcc cctcacttga cagcatatac atatgtaggg ctagagaacg
    66301 gcctgaagac atgagactac ttggcgtatt ggtagaggta cctaatgtat acatgagggc
    66361 agctgtttca ccaacgatac ggccaatagc tagtatcact ccagctaaaa tacctggcat
    66421 ggcaactggt agaacaattc taaaaacagt ccgtaactta cctgccccaa gtccataact
    66481 tgcttgacgc atgctatcac taacagataa aagggcttct tctgttgagc gaataatgac
    66541 tggcaacacc atgataactg aggttaagat tcctgataac agagagtatt gaaaacctaa
    66601 gaagactaca aagaagagca tgccaaacag accaaaaaca atggaaggaa tcccagacaa
    66661 ggtatctgag gccaatcgca tgattttaac acaaagggaa tctttttttg tatattccac
    66721 aagataaaaa ccagcaaaaa tccctatggg caaggctaaa agaagagcac caaagaccag
    66781 aataacggtg gaaataatcg ctggcataag ggaaatattc tcagaagtat aagtccaaga
    66841 aaagagggat agacttagat gaggtaagcc tttgatgagg ataaaaccaa tgattaaaaa
    66901 gagagagcca aaggttaaag ctgaaaaaca ataaacgaga agttttagca ggtatttact
    66961 cataagatga ttttcctttc aagtaggcaa agtaggcatt aatcaagaga ataaggaaaa
    67021 agagaactgc tgaggttgca ataagggctt ccctatgctg acctgatgcg taagccattt
    67081 ccagaacaat attggttgtt aaggttctgg ttcctgaaaa gagtccactt ggaataatcg
    67141 gctggttgcc tgccaccaaa ataactgcca tggtttcacc tactgcgcga ccaattccta
    67201 aaataactgc tgataaaata ccagatctcg cagctggcaa gatgacacta aaaatactcc
    67261 gttcatgact agctcctaga gccaagctac cagaataata cgttttggga actgttcgga
    67321 tagcagattc tgacaaactg ataatggttg gcaaaatcat tattcctaat agtaacgaag
    67381 cggttaggac actcatgcca tttcctaaaa aggttctaat ccaaggcacc aataattgta
    67441 ggccgaaaaa accataaaca atagatggaa tggccgccat caagttgata gctgatttta
    67501 agaagccata gacgggcttt ggacaataat aaaccataaa caccgatgtc aagatgcctg
    67561 ttggcacccc aatcacaatc gctcctaagg taattaataa ggaaccaacg atcattggta
    67621 aaataccata gcttgccgga atgttcgttg gcgaccaatc actgcctaat aaaaaacggg
    67681 caaagccgta gttagccatg aaaggtaagc cattactaaa aataaagaaa cagattagca
    67741 aaatagctac aacagctact gttgcactca tgaaaaaaat tgccctaaaa actgcttctt
    67801 tgaaggcttg ttttgtcaca tcttgtcctt tctagtgaag aaagtaaggg agatacgaca
    67861 cctccctact tgccttcttt atcttattgt acgatgaaac gtctgcatct ctttagagat
    67921 ttatggagca aacattttat ttaatcttgt cccaggtggt taatttgcca ctaaaaacgt
    67981 ctgcaagttc agccatactg acttggcttg ccttattgtc attattgacc acaacagcaa
    68041 taccgtctaa agcaatagca tcatgggtga gacttttacc ttcttcagga gttaattccc
    68101 tagaaaccat accaatatca gcggttttct ccttaacagc ggtaatacct gctgaagacc
    68161 cattagaggt aatatcaatc gtaacttctg gattttcttt tttataagct tctgctaatt
    68221 tttccattaa agaagatact gaagtggaac ctacaacaga caacttgcct gataagtgtt
    68281 ggcttgtata ttctgtggtt tcggttttag cttcaataaa tttattatct gtgaccactt
    68341 gttgaccttg tttggagtgg ataaagctga taaaatcttg acctagcttg gaaagattag
    68401 aagaccaaac aatgttgaag ggacgttgaa gagggtattc accatctaaa actgtgtctc
    68461 gactagcctt gacaccatca atctctaaag ccttgacaga tttcgttaaa gatcccaagg
    68521 agatgtagcc gatagcatta gcattccctt gaactgctga gagaacacct tctgtactat
    68581 tttgaatcac agctgttttg gcagtgttgt caattttttt atcaccgtct tttttgagaa
    68641 tccctgtgat ttctgtgaag gcaccccgtg ttccagagcc attttctcgt gaaatcacct
    68701 caatcgttcc tgaagctgac tgtttggaag cagctgactg attgccacag gcaacaagcc
    68761 caaatcctga taagccaatg gctgcaagag taagcatttt tttgaatttc ataataatca
    68821 cctttatctc tatgtatttt tcttgtgtag gcttactaca tttatagtct aacaagtctt
    68881 tgtaaaggtt tatccctgat tcatgtaaag attgtgtaaa gaatcaaaaa aagccacttt
    68941 tgaaaaatgg ctgctcctaa aaatagcttt aaaaattatt agtcctgtgc gaaagattgg
    69001 ttaggaagaa aaatcgtgaa gcaactgcct ctgccaagct gactcgtcac cgtgacttgg
    69061 ccacttaata attgactgag ttctttgaca atggcaaggc caagaccagt gccaccagtt
    69121 tgtctgcttc gacctttatt aactcggtaa aaacgttcaa aaatacgatc ctgctctaat
    69181 tgactaatac caatccctgt atctgataca gaaatcttaa tgccttcgtt caccttttgg
    69241 gtcttgacct caatttttcc cccttgttca gtgtaacgga tggcattgga taaaagattg
    69301 agtaagattt gggaaagtaa ttgactatct gatacgaggg tgacatcatc tggcacctgc
    69361 acctttagct gtaaatcctt cttcttgagc tgaggttgca agctttgagt caaatcctgt
    69421 acaaattctg ccaaagaaag ggtcgtccat tgtataggca tttgttgagc cttagataag
    69481 gtaagaagat gctcaacaat atgctcaaga cgcaaacttt ctttgtaaat aatgtctaga
    69541 aagtcatcct tgagcgcttc ttcttcagct gacatcccct taatggtttc agcaaagccc
    69601 ttaatcgaag taactggtgt cctcaattca tgggaggcat ttgagacaaa ggctaaattt
    69661 aacttttcat aagttctaat cgttgttaaa tcatatagca agacgagcac agcttccaca
    69721 gattgggtgg ggctaaaaac gggaactgct gtcacttcta aaatcaagtc accctcatga
    69781 aacccactta cttcttgttt taaccttgtt ttttgatcaa aggcttggtg aactaaattt
    69841 cgaatatcca tccgtttgag gtcatcaagt gaacttatgt cgccgtccac atcgggaaaa
    69901 taatgaggca gagagcgact ggataataac atctgacctt gagcggaaac taaaaacgtc
    69961 cccatggtta ggtgcgacag aagaacctcc attgtttcgg ctaggtcctt gtattgctga
    70021 tcctgttggg agactttggt ttttagggca gacacatact gagccaaaga ctttaagtct
    70081 tcttgccctt tttctaaaaa gtattcacta ctggtcaaga gaggttggtg caaggtctca
    70141 aaagcaactt cccatttcca aaggcaaaag agccagtagc cacctagtcc caaagaaagg
    70201 gctagaagaa agagaccgat gcctttactg atccaagtta atgccatccc tgcaatcaga
    70261 atgaggctaa cacttagatt gactagccaa aattgaaggt agcgtttcat ctataactcc
    70321 ttgaacttat aaccataccc ccgaatggtt cgaataaatt gaggggcttt aggattgtct
    70381 tcaatttttt cccttaactt accaatatga acgtccacca aacgtgtttc ctgcccaaag
    70441 tcataccccc agatacgttc caaaagacgc tctctagtca gtgtcatgtt gggatgtttc
    70501 ataagataga gcaagagttc aaattctttt ggggtcaaac tcagtaactt attcgccttg
    70561 tagacttcat gacgctcagg gtatactttc aaggtcccaa atagccaaga atcgtcagcg
    70621 atattatctg aatcatctcc ttcttgttct cctttagttc gcctgagaac agccttgaca
    70681 cgcgccagca attctctagg gctaaaaggc ttggtcaggt agtcatcagc ccctaattcc
    70741 aaggccaaaa ccttatcaaa ttcatcactt ttcgcagaaa ccatcataat tggagttttg
    70801 acgcctttgg ctctcagccg cttacaaact tccatgccat ctaattgtgg taacatgata
    70861 tcaagcaaga taaaatcaaa gggttctgtt tctgccaaag ctaaggcctt ccgtccattt
    70921 gttaccaatt gagtagaaaa gccttcctta cttaaatggt agtcaagcaa tttcagaatg
    70981 tgttcttcat catccactaa taagacttgt tttgtcatct attatctcct attggtaaca
    71041 ttataacaca attatcagaa atcctaacat tgctaaatca gattaaattt gcttatcaag
    71101 actagtatct ggtcaaacgc tcaatcatct ccttgtgctc tggataggtc gccagtagat
    71161 ctaccctttc aaataattca aaatcctcaa attcaaaacc aggagcaaca agacaagaaa
    71221 ccagagcatc atccttatca actgttgatc cccaaatagt gcccttagga acacagtagt
    71281 gaagttgttg ccctttggat atgtccaggc ctaaagtgac tgcttcgtag tgaccatctg
    71341 ctgtaatcat gtgaacagta agtggggatt ctgcatgaaa ataccagatt tcatctgctg
    71401 tcaatcggtg aaaatgtgaa ggattcgttt cttcttaata agaaataaat actggtataa
    71461 agcgcccttc ccttaccagc aaggtttata gtgtctgaag ctttttttgt ttgtctaaaa
    71521 tagccacctt caacatgggg agctaactct agagttctta tcaagtcttc tttatccgtc
    71581 ggagccaatg ggttgaagta actcttgttc aaagtggtgt tacgatttca agaactcctc
    71641 tcagttctga ggacacggta atgattgatg cgacggaagt acaaatcaat cgccctaaaa
    71701 gaagaattag cgaatgattc tggtaaaaaa aatgccacgc tatgaaggct caagcgattg
    71761 tcacaagtca agggagaatt gtttctttgg atatcgctgt gaactattgt catgatatga
    71821 agttgttcaa aatgagtcgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg
    71881 gttatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
    71941 tcaagccact aacagttgaa gataaagcct ataaccatgc gctatccaag gagagaagca
    72001 aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa
    72061 atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggtattatc aatcatgaac
    72121 taggattcta gttttgcagg aagtctatta tttggttagg tgaattagtg aagtgtttag
    72181 gcaagtgtct ctggttacga cgtcatggcc tctaaatcga ttatatttag gggtcatgac
    72241 tagtgaagca gttagctagt tcgcatataa gcggctagcg tctaacaatt aggaacttta
    72301 gttccaataa ctttaagatt acgacgtttt aggacataaa tcgatcatat ttatgtccta
    72361 aaactagtga agcgcctagc caaagtccga ataggatttg gcgttagtta cttagattgc
    72421 tttgcaatca agtaactttg gcgatttaca tcttctctgg cgcttctact ccaagcaagc
    72481 gaagggcttc tttgagaacg actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt
    72541 ctgggctttc atccaagata cgtgtatgtg catagtattt gttaaaggat tgagccaggc
    72601 taattgcaaa tttagcaatg atagaaggtt caaagttatc tgccgcacgg ttgataatac
    72661 gtgggaagtc ttgaatgagt ttaatgattt cccagctttc agtatcattc aagctatagt
    72721 tgccagctgt ttctggtttg aaatcggctt tgcgtaagat agattggata cgagcgtagg
    72781 catattgaac gtaaggtcca gtttcaccct cgaaggatac catagcctct aggtcgaagt
    72841 cgtatccatt tgtacggtcg gttttgaggt catagaattt aatggctcca accccaacag
    72901 catgtgctac ctgatcttta ttttccaatt caggattttt agcctcgatt tggaccttgg
    72961 cacggctaac agcctctgca acagtaggct ctagcaagat gacattccct ttacgagtag
    73021 agagcttctt cccttctttt gtaaccagac caaaaggaac gtgggtaatg tcgtcactcc
    73081 aatcgtagcc catctcttgc aagacagctt tgagctgttt aaagtgggca gattgttctt
    73141 gaccaacgac atagatagat ttagcaaatt ggtattcgtt tttacggtag agggctgcag
    73201 ccaagtcacg tgtgatatag agagttgcac catcagactt cttgatgagg gctggatgtt
    73261 caattccata tttctcaaga ttcacaactt gggcaccttc tgattcaaga agtagtcctt
    73321 tttcagaaag aatgtctaca actgcatcca tcttatcatt gtagaaggct tctccgttat
    73381 agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt aaattccact aaactttcat
    73441 cgcggaacca ttgccaaaga gcgagagctt cctcatctcc attttcaagt ttacggaacc
    73501 attcgcgcgc ttcttcatcc aagctagggt cattttcagc ttcagcgttg atgcggacat
    73561 agagtttaag gagttcatcg attggatgag cttttacagc ttcttcgtcg ccccattttt
    73621 tgtaggcaac aatcaacatc ccaaattgtt taccccagtc tcccaaatgg ttgaccttga
    73681 ccgtttgata accgattttt tggaaaatat gtgacaagct atctccgata acagttgaac
    73741 gcaggtggcc aatagaaaat ggtttagcga tattcggact agacatgtcg ataacaacat
    73801 tttcttgttt accaatattt tggtcagcat agtgttcttt ttcagtggta acagcttgca
    73861 atacttgagc agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga
    73921 caactttttc aaaggcttgg ctgttcattt tttcagccag ttcagccgca atcatttgtg
    73981 gtgctttacg ttcgactttg gcaagagaaa aagcagggaa agcgatgtca cccatttctg
    74041 agtttttagg ggtttccagt aactttaaaa tagcctcttg gtccaggcta tcaatgatgc
    74101 tagccaattc gctagcaatc aattcttttg tattcattaa gagctccttt ttggactttt
    74161 ctactatttt atcacaattt taaagaaaga agaaaaaatt tttgaaatct cctgtttttt
    74221 tggtataata tggttataaa tatagttata aatatgcacg caagaggatt ttatgagaaa
    74281 aagagatcgt catcagttaa taaaaaaaat gattactgag gagaaattaa gtacacaaaa
    74341 agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg
    74401 tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat gatatggtgt attatgtact
    74461 agtaaatgag acagaaaaga ttgatttggt ggaatttttg tctcatcatt tagaaggtgt
    74521 tgcaagagca gagtttacct tggtgcttca taccaaattg ggagaagcct ctgttttggc
    74581 aaatattgta gatgtaaaca aggatgaatg gattttagga acagttgctg gtgccaatac
    74641 cttattggtt atttgtcgag atcagcacgt tgccaaactc atggaagatc gtttgctaga
    74701 tttgatgaaa gataagtaag gtcttgggag ttgctctcaa gacttatttt tgaaaaggag
    74761 agacagaaaa tggcgataga aaagctatca cccggcatgc aacagtatgt ggatattaaa
    74821 aagcaatatc cagatgcttt tttgctcttt cggatgggtg atttttatga attattttat
    74881 gaggatgcgg tcaatgctgc gcagattctg gaaatttcct taacgagtcg caacaagaat
    74941 gccgacaatc cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat
    75001 gtcttgattg agcagggtta taaggtggct atcgcagagc agatggaaga tcctaaacaa
    75061 gcagttgggg ttgttaaacg agaggttgtt caggtcatta cgccagggac agtggtcgat
    75121 agcagtaagc cggacagtca gaataatttt ttggttgcca tagaccgcga aggcaatcaa
    75181 tttggcctag cttatatgga tttggtgacg ggtgactttt atgtgacagg tcttttggat
    75241 ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc gagaagtggt gttgggttat
    75301 gacttgtctg aggaagaaga acaaatcctc agccgccaga tgaatctggt actctcttat
    75361 gaaaaagaaa gctttgaaga ccttcattta ttggatttgc gattggcaac ggtggagcaa
    75421 acggcatcta gtaagctgct ccagtatgtt catcggactc agatgaggga attgaaccac
    75481 ctcaaacctg ttatccgcta cgaaattaag gatttcttgc agatggatta tgcgaccaag
    75541 gctagtctgg atttggttga gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg
    75601 cttttggatg aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg gattcatcgc
    75661 cccttgattg ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac
    75721 catttctttg agcgtagtga cttgacagac agtctcaagg gtgtttatga cattgagcgc
    75781 ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg atctcttgca gttggcgact
    75841 accttgtcta gtgtgccacg gattcgtgcg attttagaag ggatggagca acctactcta
    75901 gcctatctca tcgcacaact ggatgcaatc cctgagttgg agagtttgat tagcgcagcg
    75961 attgctcctg aagctcctca tgtgattaca gatgggggaa ttatccggac tggatttgat
    76021 gagactttag acaagtatcg ttgcgttctc agagaaggga ctagctggat tgctgagatt
    76081 gaggctaagg agcgagaaaa ctctggtatc agcacgctca agattgacta caataaaaag
    76141 gatggctact attttcatgt gaccaattcg caactaggaa atgtgccagc ccactttttc
    76201 cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc ccgtatcgag
    76261 ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg aatacgaaat atttatgcgc
    76321 attcgtgaag aggtcggcaa gtacatccag cgtttacaag ctctagccca aggaattgcg
    76381 acggttgatg tcttacagag tctggcggtt gtggctgaaa cccagcattt gattcgacct
    76441 gagtttggtg acgattcaca aattgatatc cggaaagggc gccatgctgt cgttgaaaag
    76501 gttatggggg ctcagaccta tattccaaat acgattcaga tggcagaaga taccagtatt
    76561 caactgatta cagggccaaa catgagtggg aagtctacct atatgcgtca gttagccatg
    76621 acggcggtta tggcccagct gggttcctat gttcctgctg aaagcgccca tttaccgatt
    76681 tttgatgcga tttttacccg tatcggagca gcagatgact tggtttcggg tcagtcaacc
    76741 tttatggtgg agatgatgga ggccaataat gccatttcgc atgcgaccaa gaactctctc
    76801 attctctttg atgaattggg acgtggaact gcaacttatg acgggatggc tcttgctcag
    76861 tccatcatcg aatatatcca tgagcacatc ggagctaaga ccctctttgc gacccactac
    76921 catgagttga ctagtctgga gtctagttta caacacttgg tcaatgtcca cgtggcaact
    76981 ttggagcagg atgggcaggt caccttcctt cacaagattg aaccgggacc agctgataaa
    77041 tcctacggta tccatgttgc caagattgct ggcttgccag cagacctttt agcaagggcg
    77101 gataagattt tgactcagct agagaatcaa ggaacagaga gtcctcctcc catgagacaa
    77161 actagtgctg tcactgaaca gatttcactc tttgataggg cagaagagca tcctatccta
    77221 gcagaattag ctaaactgga tgtgtataat atgacaccta tgcaggttat gaatgtctta
    77281 gtagagttaa aacagaaact ataaaaccaa gactcactag ttaatctagc tgtatcaagg
    77341 agacttcttt gacaattctc cacttttttg ctagaataac atcacacaaa cagaatgaaa
    77401 aggagctgac gcattgtcgc tcccttttgt ctatttttta aggagaaagt atgctgattc
    77461 agaaaataaa aacctacaag tggcaggccc tggcttcgct cctgatgaca ggcttgatgg
    77521 ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt cttaggcgcc ctccttactg
    77581 ggaaatatga agttatttat agtatcggga cttggttgat tggtgtggcc gtagtcggtc
    77641 tagttgctgg tggactcaat gttgtcctcg cagcctatat tgcccaagga gtttcatccg
    77701 accttcggga ggatgccttc cgtaaaattc aaactttttc ttatgctgat attgaacaat
    77761 ttaatgcggg aaatctagtc gttcgaatga caaatgatat caaccagatt cagaacgttg
    77821 tcatgatgac cttccaaatt cttttcagac ttcccctctt gttcatcggt tcgtttatcc
    77881 tagcgcttca aaccttacct tctctgtggt gggtgattgt tctcatggta gtcttgattt
    77941 ttggtttgac tgctgtcatg atgggaatga tggggcctcg ttttgctaaa tttcaaaccc
    78001 ttcttgagcg catcaatgcc attgccaagg aaaatttacg tggcgttcgt gtggtcaagt
    78061 cctttgtcca agaaaaagag caatttgcta agtttacaga ggtctcagac gagcttcttg
    78121 gtcaaaacct ttacattggt tatgcctttt cagtagtgga accctttatg atgttggttg
    78181 gttacggggc ggtcttcctc tctatttggc tggtcgcggg aatggttcag tcggatccgt
    78241 ctgttgttgg ttccatcgct tcttttgtta attacctaag ccagattatc tttaccattg
    78301 ttatggttgg atttttggga aattctgtca gccgtgccat gatttccatg cgtcgtattc
    78361 gagaaattct tgacgcagag ccagctatga ccttcaagga tatcccagat gaagagttgg
    78421 ttggaagtct tagctttgaa aatgtgacct ttacctatcc aatggacaag gaaccgatgc
    78481 tgaaagatgt gagctttact attgaacctg gtcaaatggt tggtgtagtt ggagcgactg
    78541 gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct ctttgatcca caggacgggg
    78601 ccattaaaat cggtggcaag gatattcgag aagtgagtga aggaaccctg cgtaaaacag
    78661 tttccatcgt tctccaacgt gccattcttt ttagtggaac gattgcagat aacttgagac
    78721 aggggaaggg gaatgctact ctatttgaaa tggagcgcgc agccaatatt gcccaggcta
    78781 gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa cggggaacca
    78841 atttctctgg tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc agcaatccac
    78901 gtattctgat ttttgatgat tcgacctcag ccttggatgc caaatcagag cgcttggtgc
    78961 aagaagcttt gaataaggac ttgaagggga cgacaaccat tattattgct caaaaaatta
    79021 gctcggttgt ccatgcagac aagatcttgg ttctaaatca aggacgattg attggtcaag
    79081 gcacgcatgc agacttggtt gccaacaatg ccgtttaccg tgaaatctat gaaacacaga
    79141 aatgaaagac aaactataag aaaagtcaat agttttatct aaactatttc ttatttcaat
    79201 ttgatgattt ggcgatgatt ttagagcacg gcaaaaagct attgaaaaag tccatttttt
    79261 caaaggtaat cctgtgttaa tttcagaaat tacatcactt tttgttcgtc aaatggcagc
    79321 tcttttttag gatataaaac agggttcgga taagtttttt tgcaaggtgg atgatggcta
    79381 cattgtaatg ttttccttgt tctaacttag tcttaagata ggccttaaaa gcaggtgaaa
    79441 agcgagggca tgctttggca gcttgtatga gtacctaccg cagatgaggg gaaccccgtt
    79501 tgaccattct tcctgctaaa tcaatctgac ctgactgata aatagaagaa tccagtccag
    79561 cgaaagcttg taattgagca ggattatcaa aggcatgaat atttcgaatc tcggctaaaa
    79621 tgaccgcccc taaacgattc tcaatcccag taaccgtcgt gatgaccgag ttgaactcag
    79681 ccatcaagtc attgacacat gttttcgcct tgtcaatgag cctcttgtaa tgtttgatgt
    79741 tttcattaca agagataaaa cgtttatgcg ttatcaaact catgaccaat tgaaacaaaa
    79801 agctgtggtt agatcctttc ggaaattgtc aagcgattgg aggaaatgaa ctaatccaca
    79861 gcggcttatt ccaagtatac cacttgggct ttggcagtag ctaactgcgc taaatataat
    79921 ataaggagga gtaaaatgaa gacagttcaa tttttttggc attattttaa ggtctacaag
    79981 ttctcatttg tagttgtcat cctgatgatt gttctggcga cttttgccca agccctcttt
    80041 ccagtctttt ctggacaagc ggtgacgcag ctagccaatt tagttcaagc ttatcaaaat
    80101 ggcaatccag aacttgtatg gcaaagccta tcaggaatca tggtcaatct tggcctgctg
    80161 gttttggttc tatttatctc tagtgtaata tacatgtgtc tcatgacgcg cgtgattgca
    80221 gaatcgacca acgagatgcg caaaggcctc tttggtaagc ttgctcagtt gacggtttct
    80281 ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt ttaccagtga tttggataat
    80341 atcctccaag cctttaacga aagcttgatt caggtcatga gcaatattgt tttatacatt
    80401 ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg ctctcatcac cattgccagc
    80461 accccattgg ctttccttat gctgattttc atcgtgaaaa tggcacgtaa atacaccaac
    80521 ctccagcaga aagaggtagg gaagctcaac gcctatatgg atgagagcat ctcaggccaa
    80581 aaagccgtga ttgtgcaagg aattcaagag gatatgatgg caggatttct tgaacaaaat
    80641 gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct caggaattct tttccctgtc
    80701 atgaatggga tgagcctgat taatacagcc atcgtcatct ttgctggttc ggctgtactt
    80761 ttgaatgata agtctattga aacaagtaca gccctaggtt tgattgttat gtttgcacaa
    80821 ttttcacagc agtactacca gcctattatc caagttgcag cgagttgggg aagccttcag
    80881 ttggccttta ctggagctga acgaattcag gaaatgtttg atgcagagga ggaaatccga
    80941 cctgaaaagg ctccaacctt cactaagttg caagaaagtg ttgaaatcag tcatatcgat
    81001 ttttcatact tgcctgataa acctattttg aaagatgtca gcatttctgc ccctaaaggc
    81061 cagatgacag cagttgttgg gcctacaggt tcaggaaaaa cgactattat gaacctcatc
    81121 aatcgctttt atgatgttga tgctggtggt atttattttg atggtaaaga cattcgtggc
    81181 tatgacttag atagtcttag aagcaaggtg ggaattgtat tgcaagattc ggtcttgttt
    81241 agcggaacga ttcgagacaa tatccgattt ggtgtgccag atgctaatca ggaaatggtt
    81301 gaggtagcag caaaagcaac ccacattcac gactatatcg aaagtttgcc tgataagtac
    81361 gatactctta ttgatgatga ccagagcatc ttttcaacag ggcagaagca attgatttca
    81421 atcgctcgaa ccctgatgac agatccagaa gttctcattc tcgatgaagc aacttcaaac
    81481 gtagatacgg tgacggaaag caagattcag catgccatgg aggtggttgt agcaggtaga
    81541 actagtttcg tcattgccca ccgcttgaaa accattctca atgcagatca gattattgtc
    81601 cttaaagatg gagaagtcat tgaacgtggt aaccaccatg aacttttgaa gctaggtggc
    81661 ttttattcag aactctatca caatcaattt gttttcgaat aagaaagaag ttgtcctatg
    81721 tgggcagctt tttcttgtcc ataaaaaatg tttatcacag ccttaaaaaa aacatattag
    81781 acgaaagtca ttttgagtga tatgatagga ctatcgttag tattcgaaag gagaggcatc
    81841 atggctagaa cggttgtagg agttgctgca aatctatgtc ccgtagacgc agaaggcaaa
    81901 atcattcatt catctgtatc ttgtagattc gcagagatca ttcgtcaagt cggtggtctc
    81961 cctttagtca ttcctgttgg tgatgagtca gttgtacgtg attatgtgga aatgattgac
    82021 aaactcattt tgacaggagg ccaaaatgtt catcctcagt tttatggaga gaaaaagacc
    82081 gtcgaaagcg atgattacaa tctggtccgt gacgaatttg aattggcact cttgaaggaa
    82141 gcgcttcgtc agaataaacc aattatggca atctgtcgcg gtgtccaact tgtcaatgtt
    82201 gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact ggcaaggact acctttcggg
    82261 acatctcact ctattgagac agtagaagga agcgtggtgg ctaagctatt tgggaaagaa
    82321 agtcaggtca actcagtcca tcgtcaaagc attaaagatt tggcacctaa tttccgtgta
    82381 actgctattg attcaagaga ccaaactatt gaagcgattg agtctatcga cgagcaccgc
    82441 attatcggtt tacagtggca tccagagttt ctggttaatg aagaagatgg caatttagaa
    82501 ttatttgagt atttattgaa tgaactgtaa cgattggaac atctggtcgt tctttctttt
    82561 attttttcaa aatttttaga atgtggcatt ttacgcaaac gtttgaattc tgataaaaat
    82621 tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta agcgttatga tagaaaagaa
    82681 gaaatattgg aggaagaaca tgtcacatat taaatttgat tactcaaaag ttttagacaa
    82741 atttgttgca ccacatgaag tggaatacat gcaatcacaa gtaacagcag cagatgaatt
    82801 gatccgtaaa ggaactggtg ctggtagcga cttcttggga tggttggacc ttcctgaaaa
    82861 atacgaccgc gaagaatttg accgcatctt gaaagctgct gagcaaatca agtcagacag
    82921 cgatgttttg gttgtgatcg gtattggtgg atcttacctt ggtgcaaaag cagcaatcga
    82981 cttcttgaat caccattttg ctaacttgca aacaaaagaa gaacgcaaag ctccacaaat
    83041 cctttacgca ggaaactcaa tctcatctac ttaccttgct gacttggtag agtatgttgc
    83101 agacaaagac ttctcagtaa acgtaatttc taaatcaggt acaacaactg aaccagcgat
    83161 tgctttccgt gtctttaaag aactcttgat taagaaatac ggtcaagaag aagctaacaa
    83221 acgtatctat gcaacaactg accgccaaaa gggtgctgtt aaggttgaag cagacgctaa
    83281 cggttgggga acatttgttg ttccagatga tatcggtgga cgcttctcag tattgacagc
    83341 cgttggtttg cttccaatcg cagcatcagg agctgacata aaagctctta tggaaggtgc
    83401 gaatgcagct cgcaaagact acacttcaga caaaatctct gaaaacgaag cttaccaata
    83461 cgcagctgtt cgtaacatcc tttatcgtaa aggctatgca actgagatct tggtaaacta
    83521 tgagccatca cttcaatact tctcagaatg gtggaaacaa ttggctggtg aatcagaagg
    83581 aaaagaccaa aaaggtatct acccaacttc agccaacttc tcaactgact tgcactcact
    83641 tggtcaattt atccaagaag gaactcgtat catgtttgaa acagttgtcc gtgttgacaa
    83701 acctcgtaaa aacgtgctta ttcctacttt ggaagaagac cttgacggac ttggttacct
    83761 tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact gacggtgttc ttcttgccca
    83821 cacagatggt gatgtaccaa acatgtatgt gactcttcca gagcaagacg ctttcactct
    83881 tggttacact atctacttct tcgaattggc aattgccctt tcaggttact tgaatgctat
    83941 caacccattt gaccaaccag gtgttgaagc ttataaacgt aacatgtttg cccttcttgg
    84001 aaaaccagga tttgaagaat tgagcaaaga acttaacgca cgtctataat agaagaaaag
    84061 agtggtttgc ccactctttt tactctcttt atccatagaa attggactca gccaagactt
    84121 gtgatataat atagaaagca aaaaggcaga cgcctagata ataggagaaa ctatgtcaaa
    84181 agatatccgc gtacgttacg caccaagtcc aacaggacta ctacacatcg gaaatgcccg
    84241 tacagcattg tttaactact tgtatgcgcg ccatcatggt ggaacatttc tcatccgtat
    84301 cgaagatact gaccgtaaac gccatgtcga ggatggtgaa cgttcacaac ttgaaaacct
    84361 tcgctggtta ggcatggatt gggatgaaag tccagaatca catgagaatt atcgccagtc
    84421 tgagcgtttg gacttgtatc aaaaatacat tgaccaacta ttagctgaag gaaaagccta
    84481 taaatcttac gttacagaag aagagttggc agctgaacgt gaacgtcaag aagctgctgg
    84541 tgaaacacct cgatatatca acgaatacct tggtatgagt gaagaggaaa aagcggctta
    84601 tatcgcagaa cgtgaagcag ctggtatcat accaacagtt cgtttggctg tcaatgagtc
    84661 aggtatctac aagtggcatg atatggtcaa aggtgatatc gaatttgaag gtggcaatat
    84721 cggcggtgac tgggttatcc aaaagaaaga cggttaccca acttacaact ttgccgttgt
    84781 tatcgatgac cacgatatgc aaatctctca tgttatccgt ggagatgacc atattgctaa
    84841 tacaccaaaa cagcttatgg tctatgaagc tcttggttgg gaagctccag agtttggtca
    84901 catgaccttg attatcaact ctgagactgg taagaagtta tctaaacgtg atactaatac
    84961 acttcaattt atcgaagatt accgaaagaa aggttacctt ccagaagcag tctttaactt
    85021 tattgctctt cttggttgga acccaggtgg tgaagatgag attttctctc gtgaagaact
    85081 cattaaactt tttgatgaaa accgcctcag caagtcacca gcagcctttg atcagaaaaa
    85141 attagactgg atgagcaatg attatatcaa gaatgcagac cttgaaacca tctttgaaat
    85201 ggcaaaacca ttcttagagg aagcaggccg tttgactgac aaggctgaaa aattagttga
    85261 gctctataaa ccacaaatga aatcagtaga tgagattatc ccattgacag atcttttctt
    85321 ctcagatttc ccagaattga cagaagcaga gcgcgaagtc atgacgggtg aaacagttcc
    85381 aacagttctt gaagcattca aagcaaaact tgaagcgatg acagatgatg aatttgtgac
    85441 agaaaatatc ttcccacaaa ttaaagcagt ccaaaaagaa acaggtatta aagggaaaaa
    85501 tcttttcatg cctattcgta tcgcagtttc aggcgaaatg catgggccag aattaccaga
    85561 tacaattttc ttgcttggac gtgaaaaatc aattcagcat atcgaaaaca ttctaaaaga
    85621 aatctctaaa taaagaggat acaataatgg acatctggga aaagatgtac gaagaagcac
    85681 agaaactata caatccacat gaagtatcag actttgttta tgccaatcat gttgtagctg
    85741 cagtagaagc aggagatgga caaatattta caggattctg tatggaggga acctgtggtg
    85801 ttttccatct ctgcgcagaa cgggcggccc tcttcaatat gtaccaattt tcaggacaaa
    85861 ctaaggttaa gaaagtatta gcctttcgag ataaaccacc ttatggtgga agttcagcca
    85921 tgccttgcgg tgcttgtaga gaattccttt tagagcttaa tgctgaaaat aaagatgcag
    85981 aattcatgat ggactataat ataagaaaaa cagttaaagt ctcagaacta atcccttatt
    86041 ggtggggaga agaacgtgct tctaagttta atgagcgata gaagagtcag tataattctg
    86101 gctcttttta ctataaattg aaaaaataaa aaaaattaga aaaagtagtt gacaaagttt
    86161 gaaaagactg tataatagta agagttgaaa ataacaactc aggtccgttg gtcaaggggt
    86221 taagacaccg ccttttcacg gcggtaacac gggttcgaat cccgtacgga ctatggtatg
    86281 ttgcgtcagg agcacttgat gaaaaaaagt t
//
LOCUS       DAVHSI010000002        85158 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.002, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000002 DAVHSI010000000
VERSION     DAVHSI010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 85158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.002"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            495..2108
                     /locus_tag="VVR21_000088"
     CDS             495..2108
                     /locus_tag="VVR21_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU6054052.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSHEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            2238..2864
                     /gene="gmk"
                     /locus_tag="VVR21_000089"
     CDS             2238..2864
                     /gene="gmk"
                     /locus_tag="VVR21_000089"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU6054053.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            2889..3203
                     /locus_tag="VVR21_000090"
     CDS             2889..3203
                     /locus_tag="VVR21_000090"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU6054054.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            3269..5665
                     /locus_tag="VVR21_000091"
     CDS             3269..5665
                     /locus_tag="VVR21_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU6054055.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKDVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            5678..6613
                     /locus_tag="VVR21_000092"
     CDS             5678..6613
                     /locus_tag="VVR21_000092"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU6054056.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEDQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            6606..7919
                     /gene="rsmB"
                     /locus_tag="VVR21_000093"
     CDS             6606..7919
                     /gene="rsmB"
                     /locus_tag="VVR21_000093"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU6054057.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKVFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            7934..8674
                     /locus_tag="VVR21_000094"
     CDS             7934..8674
                     /locus_tag="VVR21_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU6054058.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            8671..10650
                     /gene="pknB"
                     /locus_tag="VVR21_000095"
     CDS             8671..10650
                     /gene="pknB"
                     /locus_tag="VVR21_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU6054059.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVNLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            10765..11523
                     /locus_tag="VVR21_000096"
     CDS             10765..11523
                     /locus_tag="VVR21_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6054060.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            11525..11974
                     /locus_tag="VVR21_000097"
     CDS             11525..11974
                     /locus_tag="VVR21_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU6054061.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            12036..12659
                     /locus_tag="VVR21_000098"
                     /pseudo
     CDS             12036..12659
                     /locus_tag="VVR21_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12727..12975
                     /locus_tag="VVR21_000099"
     CDS             12727..12975
                     /locus_tag="VVR21_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054062.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            13106..14278
                     /locus_tag="VVR21_000100"
     CDS             13106..14278
                     /locus_tag="VVR21_000100"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU6054063.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            14278..15552
                     /locus_tag="VVR21_000101"
     CDS             14278..15552
                     /locus_tag="VVR21_000101"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU6054064.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMAILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(15588..16553)
                     /locus_tag="VVR21_000102"
     CDS             complement(15588..16553)
                     /locus_tag="VVR21_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6054065.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(16534..17988)
                     /locus_tag="VVR21_000103"
     CDS             complement(16534..17988)
                     /locus_tag="VVR21_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6054066.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDHFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            18365..20248
                     /locus_tag="VVR21_000104"
     CDS             18365..20248
                     /locus_tag="VVR21_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6054067.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKAGDVLGTFDSNKIAAAGLDDTTMLIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            20397..21284
                     /locus_tag="VVR21_000105"
     CDS             20397..21284
                     /locus_tag="VVR21_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6054068.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPSWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(21604..22221)
                     /locus_tag="VVR21_000106"
     CDS             complement(21604..22221)
                     /locus_tag="VVR21_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU6054069.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(22636..22849)
                     /locus_tag="VVR21_000107"
                     /pseudo
     CDS             complement(22636..22849)
                     /locus_tag="VVR21_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23334..23414)
                     /locus_tag="VVR21_000108"
                     /pseudo
     CDS             complement(23334..23414)
                     /locus_tag="VVR21_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            23531..24424
                     /locus_tag="VVR21_000109"
     CDS             23531..24424
                     /locus_tag="VVR21_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054070.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            24421..25620
                     /locus_tag="VVR21_000110"
     CDS             24421..25620
                     /locus_tag="VVR21_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054071.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(25973..26740)
                     /locus_tag="VVR21_000111"
     CDS             complement(25973..26740)
                     /locus_tag="VVR21_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054072.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYK
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(26757..27452)
                     /locus_tag="VVR21_000112"
     CDS             complement(26757..27452)
                     /locus_tag="VVR21_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054073.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(27457..27822)
                     /locus_tag="VVR21_000113"
     CDS             complement(27457..27822)
                     /locus_tag="VVR21_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6054074.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            27962..28435
                     /gene="nrdR"
                     /locus_tag="VVR21_000114"
     CDS             27962..28435
                     /gene="nrdR"
                     /locus_tag="VVR21_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU6054075.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            28436..29605
                     /locus_tag="VVR21_000115"
     CDS             28436..29605
                     /locus_tag="VVR21_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU6054076.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            29606..30502
                     /gene="dnaI"
                     /locus_tag="VVR21_000116"
     CDS             29606..30502
                     /gene="dnaI"
                     /locus_tag="VVR21_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU6054077.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            30499..31212
                     /locus_tag="VVR21_000117"
     CDS             30499..31212
                     /locus_tag="VVR21_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU6054078.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLKQKKLL"
     gene            31226..32536
                     /gene="der"
                     /locus_tag="VVR21_000118"
     CDS             31226..32536
                     /gene="der"
                     /locus_tag="VVR21_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU6054079.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            32627..32962
                     /locus_tag="VVR21_000119"
     CDS             32627..32962
                     /locus_tag="VVR21_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054080.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            33102..33437
                     /locus_tag="VVR21_000120"
     CDS             33102..33437
                     /locus_tag="VVR21_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054081.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYIPLY
                     ALFSLSWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            33622..34413
                     /locus_tag="VVR21_000121"
     CDS             33622..34413
                     /locus_tag="VVR21_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054082.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLEKYEDNV"
     gene            34406..35047
                     /locus_tag="VVR21_000122"
     CDS             34406..35047
                     /locus_tag="VVR21_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054083.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            35051..35701
                     /locus_tag="VVR21_000123"
     CDS             35051..35701
                     /locus_tag="VVR21_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6054084.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            35712..35999
                     /locus_tag="VVR21_000124"
     CDS             35712..35999
                     /locus_tag="VVR21_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054085.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            36145..38658
                     /gene="secA"
                     /locus_tag="VVR21_000125"
     CDS             36145..38658
                     /gene="secA"
                     /locus_tag="VVR21_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU6054086.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            38739..39770
                     /locus_tag="VVR21_000126"
     CDS             38739..39770
                     /locus_tag="VVR21_000126"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6054087.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            39772..40803
                     /locus_tag="VVR21_000127"
     CDS             39772..40803
                     /locus_tag="VVR21_000127"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU6054088.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            40842..41210
                     /locus_tag="VVR21_000128"
     CDS             40842..41210
                     /locus_tag="VVR21_000128"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU6054089.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            41200..42303
                     /locus_tag="VVR21_000129"
     CDS             41200..42303
                     /locus_tag="VVR21_000129"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU6054090.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            42322..44337
                     /gene="recG"
                     /locus_tag="VVR21_000130"
     CDS             42322..44337
                     /gene="recG"
                     /locus_tag="VVR21_000130"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU6054091.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHYMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            44654..45634
                     /locus_tag="VVR21_000131"
     CDS             44654..45634
                     /locus_tag="VVR21_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU6054092.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(45956..46447)
                     /locus_tag="VVR21_000132"
     CDS             complement(45956..46447)
                     /locus_tag="VVR21_000132"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054093.1"
                     /translation="MVDKTDEVSSKHCFEVADRTDEVSSKHRFEVADRTDEVSSKHRF
                     EVADRTDEVSSKHRFEVADRTDEVSSKHRFEVVDRTDEVSSKHCFEVVDRTDEVSSKH
                     CFEVVDRTDEVSSKHCFEVVDRTDEVSSKHCFEVVDRTDEVSNHTYGKTKLTWFKEIF
                     EKY"
     gene            46800..47027
                     /locus_tag="VVR21_000133"
     CDS             46800..47027
                     /locus_tag="VVR21_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054094.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            47315..50212
                     /gene="nanA"
                     /locus_tag="VVR21_000134"
     CDS             47315..50212
                     /gene="nanA"
                     /locus_tag="VVR21_000134"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU6054095.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAVLTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            51227..51679
                     /locus_tag="VVR21_000135"
     CDS             51227..51679
                     /locus_tag="VVR21_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6054096.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFIYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            51698..53035
                     /locus_tag="VVR21_000136"
     CDS             51698..53035
                     /locus_tag="VVR21_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU6054097.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            53114..53998
                     /locus_tag="VVR21_000137"
     CDS             53114..53998
                     /locus_tag="VVR21_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6054098.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            53998..54831
                     /locus_tag="VVR21_000138"
     CDS             53998..54831
                     /locus_tag="VVR21_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6054099.1"
                     /translation="MKKKSGIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            54850..56943
                     /gene="nanB"
                     /locus_tag="VVR21_000139"
     CDS             54850..56943
                     /gene="nanB"
                     /locus_tag="VVR21_000139"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU6054100.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            56955..58058
                     /locus_tag="VVR21_000140"
     CDS             56955..58058
                     /locus_tag="VVR21_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6054101.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDVCKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVRLSEIVK"
     gene            58232..58930
                     /locus_tag="VVR21_000141"
     CDS             58232..58930
                     /locus_tag="VVR21_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU6054102.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEVGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            58949..60466
                     /locus_tag="VVR21_000142"
     CDS             58949..60466
                     /locus_tag="VVR21_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6054103.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRSLGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            60591..61919
                     /locus_tag="VVR21_000143"
     CDS             60591..61919
                     /locus_tag="VVR21_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6054104.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            62171..63037
                     /locus_tag="VVR21_000144"
     CDS             62171..63037
                     /locus_tag="VVR21_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6054105.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            63053..63892
                     /locus_tag="VVR21_000145"
     CDS             63053..63892
                     /locus_tag="VVR21_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6054106.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            64165..64617
                     /locus_tag="VVR21_000146"
     CDS             64165..64617
                     /locus_tag="VVR21_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU6054107.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            64714..65058
                     /locus_tag="VVR21_000147"
     CDS             64714..65058
                     /locus_tag="VVR21_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054108.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIIRGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVRLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     HDKIPNNGRINF"
     gene            65345..65989
                     /locus_tag="VVR21_000148"
     CDS             65345..65989
                     /locus_tag="VVR21_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6054109.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            66158..67075
                     /locus_tag="VVR21_000149"
     CDS             66158..67075
                     /locus_tag="VVR21_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU6054110.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            67093..67977
                     /locus_tag="VVR21_000150"
     CDS             67093..67977
                     /locus_tag="VVR21_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6054111.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(67993..68844)
                     /locus_tag="VVR21_000151"
     CDS             complement(67993..68844)
                     /locus_tag="VVR21_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU6054112.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            69044..71101
                     /gene="pbp2b"
                     /locus_tag="VVR21_000152"
     CDS             69044..71101
                     /gene="pbp2b"
                     /locus_tag="VVR21_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU6054113.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            71112..71708
                     /gene="recR"
                     /locus_tag="VVR21_000153"
     CDS             71112..71708
                     /gene="recR"
                     /locus_tag="VVR21_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU6054114.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            71884..72927
                     /locus_tag="VVR21_000154"
     CDS             71884..72927
                     /locus_tag="VVR21_000154"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU6054115.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFIVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAEAAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            73011..74384
                     /locus_tag="VVR21_000155"
     CDS             73011..74384
                     /locus_tag="VVR21_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU6054116.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            74371..74982
                     /locus_tag="VVR21_000156"
     CDS             74371..74982
                     /locus_tag="VVR21_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6054117.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            75073..75777
                     /locus_tag="VVR21_000157"
     CDS             75073..75777
                     /locus_tag="VVR21_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU6054118.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            75996..77369
                     /gene="ftsA"
                     /locus_tag="VVR21_000158"
     CDS             75996..77369
                     /gene="ftsA"
                     /locus_tag="VVR21_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU6054119.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            77386..78645
                     /gene="ftsZ"
                     /locus_tag="VVR21_000159"
     CDS             77386..78645
                     /gene="ftsZ"
                     /locus_tag="VVR21_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU6054120.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            78650..79321
                     /locus_tag="VVR21_000160"
     CDS             78650..79321
                     /locus_tag="VVR21_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU6054121.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            79331..79870
                     /locus_tag="VVR21_000161"
     CDS             79331..79870
                     /locus_tag="VVR21_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU6054122.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            79870..80133
                     /locus_tag="VVR21_000162"
     CDS             79870..80133
                     /locus_tag="VVR21_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU6054123.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            80130..80915
                     /locus_tag="VVR21_000163"
     CDS             80130..80915
                     /locus_tag="VVR21_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU6054124.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            80924..81712
                     /gene="divIVA"
                     /locus_tag="VVR21_000164"
     CDS             80924..81712
                     /gene="divIVA"
                     /locus_tag="VVR21_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU6054125.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLVQLAQCMKNQK"
     gene            82060..84852
                     /locus_tag="VVR21_000165"
     CDS             82060..84852
                     /locus_tag="VVR21_000165"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU6054126.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYQNEVVKTLLEAVNSNVAQLLIV
                     SELTIVEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        25778 a        15672 c        18932 g        24776 t
ORIGIN      
        1 tagaagtgat gatgttatcc atcgtctact agaacataga actcccaata atattaaaac
       61 ttatttttca aaaaatgaag aagataataa attgattaat gagtatattt taaaagcttt
      121 cgatgaggat aaattaatac ttaagaaata aattgataca actaaataaa aaaagttaat
      181 ttatgacaaa tttgatcttg aagataagct gtaatttcct aaagtgaatt ttcaaagact
      241 tgaaagcaaa atgtttgaat ctagtggaac actatttggc acaacaatag aaaatccata
      301 gttgtagaaa ttcggtggaa ctttttgata gcgacactga cttatctcct taaaaaacca
      361 aggaagtgta atcctaaaat tcagactaaa ttccccaaaa catattctat tttaggtttg
      421 tgaaaatcac ttttttatgg tagaatgtaa aagaatgtgt gtcattcgga ataacaataa
      481 aatgaggtaa aaacatggag atcatgtcgc ttgcgattgc tgtttttgcc gtcatcattg
      541 gtttagtcat tggatatgtc agcatctcag ctaagatgaa atcatctcat gaagctgcag
      601 agttgatgct tttaaatgct gaacaagaag caactaattt acgtggacaa gctgagcgtg
      661 aagcggattt acttgttaat gaagccaaac gtgaaagcaa gtctcttaaa aaagaagcac
      721 tattggaggc caaagaagaa gccagaaaat accgtgaaga agtggacgct gaatttaaat
      781 cagaacgtca agaactcaaa caaatcgaaa gtcgtttgac agagagagct actagccttg
      841 accgtaagga cgacaatttg acgagtaaag aacaaacact tgaacaaaaa gaacaaagta
      901 tttctgatag agcgaaaaac cttgatgcgc gtgaagagca attagaggaa gtcgaaagac
      961 aaaaagaagc agaactagag cgtattggtg ctctgtctca ggcagaagca cgagatatta
     1021 tcttggctca gacagaggaa aacttgacca gggagattgc cagtcgcatt cgcgaagctg
     1081 agcaagaggt caaggaacgt tctgacaaaa tggccaagga catcttggtt caagctatgc
     1141 aacgtatcgc tggtgaatat gtagcggagt caacaaactc aacagttcat ctgccagacg
     1201 atactatgaa gggacgcatt attggtcgtg aaggtcgtaa cattcgtacc tttgaaagtt
     1261 tgacaggggt cgatgtgatt atcgacgata caccagaagt ggtgaccttg tcaggatttg
     1321 atccgattcg tcgtgagatt gcccgtatga ctatggaaat gttgctcaaa gatggtcgta
     1381 tacatccagc tcgtatcgaa gagttggttg agaaaaaccg tcaagagatt gacaataaga
     1441 ttcgtgaata cggtgaggct gctgcctatg aaattggtgc gccaaacctt catccagact
     1501 tgatgaagat tatgggacgt ttgcagttcc gtacttcata tggacaaaat gttttgcgcc
     1561 attcgattga ggttgctaag ttggctggta tcatggcgag cgaacttggt gaaaatgcgg
     1621 ctcttgcccg tcgtgctgga ttccttcacg atatcgggaa agccattgac catgaggttg
     1681 aaggtagcca cgttgaaatc ggtatggaat tggcccgtaa gtacaaggaa cccccagttg
     1741 tggtgaatac gattgctagt caccacggag atgttgaagc tgagagcgtg atagcagtta
     1801 tcgtcgctgc agcagatgcc ttgagcgcag cccgtccagg tgctcgtagt gagtctcttg
     1861 aaagctacat caagcgtctc catgatttgg aagaaattgc taacggcttt gaaggagtgc
     1921 aaactagctt tgcccttcaa gcaggacgtg aaattcgtat catggtcaat ccaggaaaaa
     1981 tcaaggacga caaagtcaca atcttggctc acaaagttcg taagaaaatt gaaaacaatc
     2041 tcgattatcc aggaaatatc aaggtaaccg tgattcgcga gcttcgtgca gtagattatg
     2101 ctaaataaat aagaaagagc agttgaaaaa ttactgcttt tttgttacac tagatagaaa
     2161 gactgtaaag gataatctgg ctttttgcca ttattctaga gaaatgttat ttcacagatt
     2221 gactaaaagg agacacaatg gcagaccgag gcttactaat cgttttttct ggtccttcag
     2281 gggttggaaa aggaacggtt agaagagaga tttttgagag ttctgaaaac caatttcaat
     2341 actctgtatc gatgacgaca cgcgcacaac gtcctggaga agtggacggt gttgactatt
     2401 tcttccgtac tcgtgaagaa tttgaagagc tgattcgtca aggacagatg ttggaatacg
     2461 cagaatatgt cggcaactac tatggaactc ctctgaccta tgtcaatgaa accttggaca
     2521 agggaatcga tgttttcctt gaaattgaag ttcagggtgc tcttcaggtc aagaaaaagg
     2581 ttccagatgc tgtctttatc ttcctgacac caccagattt ggatgaattg caagatcgct
     2641 tggtaggtcg tggaacagat agtgcagaag tgattgccca acgaatcgaa aaggccaagg
     2701 aagaaattgc cctcatgcgt gagtatgatt atgcgattgt caacgatcag gtgcccctag
     2761 ctgctgaacg tgtcaaatgt gtgattgaag cagaacactt ctgtgtggat cgtgtcattg
     2821 gtcactatca ggagatgtta ccaaaatctc caactacccg ataaaattta gaaaataggt
     2881 acaagcaaat gatgttaaaa ccctctattg ataccttgct cgacaaggtt ccttcaaaat
     2941 attcactcgt aatcttggaa gcaaaacgtg cccacgaatt ggaagcaggt gccccagcaa
     3001 ctcaaggttt caagtctgaa aaatcaactc ttcgcgcttt agaagaaatc gaatcaggaa
     3061 acgttacaat tcacccagat ccagaaggaa aacgtgaagc agtgcgtcgc cgtatcgaag
     3121 aagaaaaacg ccgcaaagaa gaagaagaaa agaaaatcaa agagcaaatt gctaaagaaa
     3181 aagaagatgg tgaaaaaatt taaggttggg gggactcaat cttatttttt ctattgcaag
     3241 aatgtactga caaggaggag gtgagaagat ggccctagct aagattatcg tagatgtgcc
     3301 cttgatgcag acggaccagc cctatagtta caggattccg gaggaatttg agggaatgct
     3361 ggaagttggg atgcgggttc atgtaccttt tggtaagggt aatcgcctga ttcaagggat
     3421 tgttcttggt ttggagtccc aatcagatgg agaagagatg gagcaagatt taaaagatat
     3481 tgcagaggtg ctggattttt ctcctgttct cacgccagaa caactctggc tggctgagga
     3541 gttacgcaaa tctgtcttct cctacaaaat ctctatcctc aaggccatgc ttccaggatt
     3601 tctgaattct agctatgaca agattctcta tcctctggaa ggcttgagtc aggaagaacg
     3661 agtgcgcctg tttggttcag aagattcgct agccttttct tcactagacc ttgccaagca
     3721 agctgaaatg atgcgtttga ctagaaaagg cctgcttggt ctggaatatc aggcagtcga
     3781 tcaaaagaag gtcaagaccc agtcttggta tgaggttgac catgctcaat tagaaggtgt
     3841 tgagatttct acacgtgcca agaaaaagtt ggaactgaga gattatctgc tgtctcatcc
     3901 agagagcgct tccttggcta gcttgttaga gtcctactcg cgagagcaag tcaacttctt
     3961 tgtggatcaa ggtgctgtta ccatagtcca aaaggaagtt cgacgctcgg ctgcttattt
     4021 tgaaggaatt gaagcaagta gacctttgga gttaaatcca gaacaaagac aggcgcgtga
     4081 tgcggttgtg agttctattg gcagttctca acctcccttt ctacttcaag ggattacagg
     4141 aagtgggaag accgaggttt acttgcagat tatccaaggt gccctggata agggcaagac
     4201 agctattttg ctggtacctg agatttcctt gactcctcag atgaccgagc gttttatagc
     4261 acgttttggg gacaaggtag ccattcttca ctcaggatta tccaatggtg aaaagtatga
     4321 tgaatggcgc aaggtggagc gtggcgatgc ccaagttgtt gttggtgcca gatctgctat
     4381 ctttgctcct ctgaaaaatc tgggtgtcat gattattgat gaagagcatg aagcggctta
     4441 taagcaggac agcaatcccc gttatcatgc cagagaggta gctattttac gggctcagta
     4501 taatcaagca actctggtac ttggatctgc aacgccgagc ttagagagcc gggcgcgtgc
     4561 tggcaaagac gtctatcaac acttacgtct aacccaacgt gccaatcctt tggctacaat
     4621 ccctgaggtt caagtgattg actttcgaga ctatatcgga caaaatgaga cgtcaaactt
     4681 tacgcctcct ttgctagagg ctatccaaga ccgtctggtt aaaaaagagc aggtggttct
     4741 catgctcaat cgccgtggtt attctagctt tgtcatgtgt cgggagtgtg ggacggtgga
     4801 tacttgtccc aactgcgata tttctctgac cttgcatatg gataccaaga ctatgaactg
     4861 ccattattgt ggtttctcga aggatattcc tcaggtctgt cctaactgta agagccacag
     4921 tattcgttac tatgggacgg gaactcagaa ggcttatgat gagctagcag aactctttcc
     4981 ccaagctcgc attctgagga tggatgtgga tacgactcga aagaaaggca gtcaccaagc
     5041 cttgcttgac cagtttgggc gaggggaagc ggatatttta cttggtactc agatgattgc
     5101 aaagggtttg gattttccca atgttaccct agtcggagtt ctaaatgcgg atacggcctt
     5161 gaatctgcct gatttccgtt cttctgagag aaccttccag ctcttgactc aggtggcagg
     5221 tcgagcaggt cgggctgaaa aagcaggtca agtcttgata cagtcctaca atccgcagca
     5281 ctatgctatt cgatttgcca aggatcaaga ttacgaaggc ttttatgcct atgaaatggg
     5341 aatcagacga caactcggct atccacctta ctatttcacg attggtatta ccctttctca
     5401 caagaaagaa gaagaggttt tcaaacgtgc ctatgaagtc atgaacattt tgcggtcagg
     5461 cttgtcagag accagtccca ttctggggcc aacgccaaaa ccgattgccc gtacccacaa
     5521 cctctatcat taccagattt taattaaata ccgtttagaa gatgagctgg ggccgaccct
     5581 caaccaggtc ttggccttga ctcaagaacg ggaaaatagt gagctccgtc tcagcattga
     5641 ccatgagccg cagcaatttt tataaaaagg agaagatatg acaaaactaa tctttatggg
     5701 gacccccgac ttttcagcaa cagtcttaaa aggacttttg acagatgacc gttacgaaat
     5761 tctagccgtt gtgacccagc cagaccgtgc tgttggtcgt aaaaaagtta tccaagaaac
     5821 cccagtcaag caggctgcca aggaagcagg actatctatc taccaacctg aaaaattatc
     5881 tggaagtcca gagatggaag atcttatgaa gctaggagca gatggaattg tgactgctgc
     5941 ttttgggcag tttctcccaa gcaaactcct tgatagcatg gactttgctg tcaacgttca
     6001 tgcctccctc cttcctagac accgtggtgg tgcgcctatc cattatgcct tgattcaagg
     6061 ggatgaggaa gctggtgtga ccatcatgga aatggttaag gaaatggatg caggagatat
     6121 gatttctcgt cgcagcattc cgatcacaga tgaggacaat gttggcacct tgtttgaaaa
     6181 attggcgcta gttggtcgtg atttgctttt ggacactctg cctgcctata ttgctggtga
     6241 tatcaaacct gaaccgcagg atacgagtca ggttaccttc tctccaaata taaagccaga
     6301 ggaagaaaaa ctggactgga acaaaaccaa tcgtcaactc tttaaccaaa ttcgtggaat
     6361 gaacccctgg cctgttgccc atactttcct taagggcgac cgctttaaga tttatgaagc
     6421 cctaccagta gaagatcagg gaaatccagg tgagattctc tctatcggca agaaagaatt
     6481 gattgtcgca acggctgaag gggctctatc cctcaaacaa gtgcagccag ctggtaagcc
     6541 taagatggac attgcttcct ttctcaacgg agttggacgt acattgactg taggagaacg
     6601 atttggtgac taaagtagaa acggctagaa gtttagctct agcagtgcta gaggatgttt
     6661 ttgtgaatca agcatattca aatattgcct taaataaaca cctcaagggg agtcagctct
     6721 ctgcagcaga caagggctta gtgaccgagc tggtctatgg aacggtagcc cgtaaattga
     6781 ctctggaatg gtacctatcc cactttatcg aagacagaga ccagttagac agctggctct
     6841 atgtccttct tctcatgagt gcctaccaac tccgctattt ggacaagatt ccagatcatg
     6901 ctgtggtcaa tgaagcagtg gaattggcca aactccgtaa aaaaggcagt gaaaaattgg
     6961 tcaacgctgt ccttcgccgt atcttgcgtg aaggctggcc agatattgct agcatcaagc
     7021 gaaaaaacaa gcgtgactcc attgcctatt ctctcccagt ttggctagtt gccaaactca
     7081 aggaagaata cggagaggag agagcaaaag ccatctttga aagcctgtta gtgcgaaaca
     7141 aagccagtat tcgtgtaaca gacctaagtc gaaaagagga aatccaagcc ttgttggagg
     7201 cgaataattc ccttttagca acaactggtc tggttaagga gcaagggcat tttgcagggc
     7261 ataatttgtt tgcgaatgga gccattacca tccaagacga gtccagtcag ctggttgctc
     7321 cgacgcttga tttacaaggt gatgagcgag tgcttgatgc ctgtgcggct ccaggtggga
     7381 aaacagccca tatagcctct tatcttacga caggtcaggt tactgctctg gacttgtacg
     7441 accacaagtt ggatttaatt caagaaaatg cccaacgtct gggagttgca gatcgggttc
     7501 aaactcaaaa attggatgcc agaaaggtgc atgagttttt tgaccaggat tcctttgata
     7561 agattttggt ggatgctcct tgttcaggaa tcggtctttt gcgccgaaaa ccagatatca
     7621 aatacaataa agaaacggca gatttcgcgt ccttgcagga aattcagtta gaaatattag
     7681 gtagtgtttg tcaaatacta ggcaaaggtg gtataataac ttatagcacc tgcactatcg
     7741 tctcagagga gaattttcaa gtcgttaagg tctttttaga gagtcatccc gagttcgagc
     7801 aggtaaaact agaacatgaa tgtaaggata tcatgaaaga cggctgtatc ctcattacac
     7861 ctgaattgta tggaagtgat ggattcttca tcagtcaatt tcgcaagata tcggattagg
     7921 aaggaactga cacatggaaa tttcattatt aacagatgtt ggtcagaaac gaacaaataa
     7981 ccaagactat gtcaaccact atgtcaatag agctggacgt accatgatta ttttagctga
     8041 tgggatggga ggtcatcgcg cagggaatat cgctagtgaa atggcggtga cagacctggg
     8101 tgtagcttgg gttgataccc agatcgatac agtcaatgaa gtgcgtgaat ggttcgccca
     8161 ttacctagaa attgaaaatc aaaagattca ccagcttggt caggatgaag cttacagagg
     8221 catgggaact actttggaag tccttgctat tattgataat caggctatct atgctcatat
     8281 tggtgattcg cgtatcggct tgattcgtgg agaagaatac catcagttga cgagcgatca
     8341 ttctttggtt aatgaattgc tcaaggctgg tcaattgaca ccagaagagg cagaagctca
     8401 tccgcaaaaa aatattatca cccagtctat tgggcaaaaa gatgaaattc agcctgattt
     8461 tgggacagtt atccttgagt caggtgacta tctcttgctc aatagtgacg gcttgaccaa
     8521 catgatttca ggcagtgaga ttcgtgatat tgtaaccagt gatattcctt tagcagataa
     8581 aacggagaca cttgttcgtt ttgctaacaa tgcaggaggt ttagacaaca ttacggttgc
     8641 ccttgtttct atgaacgagg aggatgcaga atgatccaaa tcggcaagat ttttgccgga
     8701 cgctatcgga ttgtcaaaca gattggtcga ggaggcatgg cggatgtcta cctagccaaa
     8761 gacttaatct tagatgggga agaagtggca gtgaaggttc tgaggaccaa ctaccagacg
     8821 gacccgatag ctgtagctcg ttttcagcgt gaagcgagag ctatggcaga tctagaccat
     8881 cctcatatcg ttcggataac agatattggc gaggaagacg gtcaacagta cctagctatg
     8941 gagtatgtgg ctggactgga cctcaaacgc tatatcaagg aacattatcc tctttctaat
     9001 gaagaagcag tccgtatcat gggacaaatt ctcttggcta tgcgcttggc ccatactcga
     9061 ggaattgttc acagggactt gaaacctcaa aatatccttt tgacaccaga tgggactgcc
     9121 aaggtcacag actttgggat tgctgtagcc tttgcagaga caagtctgac ccagactaac
     9181 tcgatgttgg gctcagttca ttacttgtca ccagagcagg cgcgtggttc gaaggcgact
     9241 gtgcagagtg atatctatgc catggggatt attttctatg agatgttgac aggccatatc
     9301 ccttatgacg gggatagcgc ggtgaccatt gccctccagc atttccagaa acccctgccg
     9361 tccgttattg cagaaaatcc atctgtacct caggctttag aaaatgttat tatcaaggca
     9421 actgctaaaa agttgaccaa tcgctaccgc tcggtttcag agatgtatgt gaacttgtct
     9481 agtagcttgt cctacaatcg tagaaatgaa agtaagttaa tctttgatga aacgagcaag
     9541 gcagatacca agaccttgcc aaaggtttct cagagtacct tgacatctat tcctaaggtt
     9601 caagcgcaga cagaacacaa atcaatcaaa aacccaagcc aggctgtgac agaggaaact
     9661 taccaaccac aagcaccgaa aaaacataga tttaagatgc gttacctgat tttgttggcc
     9721 agccttgtat tggtggcagc ttctcttatt tggatactat ccagaactcc tgcaaccatt
     9781 gccattccag atgtggcagg tcagacagtt gcagaggcca aggcaacgct caaaaaagcc
     9841 aattttgaga ttggtgagga gaagacagag gctagtgaaa aggtggaaga agggcggatt
     9901 atccgtacag atcctggcgc tggaactggt cgaaaagaag gaacgaaaat caatctggtt
     9961 gtctcatcag gcaaacaatc cttccaaatt agtaattatg tcggccggaa atcttctgat
    10021 gttatcgcgg aattaaaaga gaaaaaagtt ccagataatt tgattaaaat tgaggaagaa
    10081 gagtcgaatg agagtgaggc tggaacggtc ctgaagcaaa gtctaccaga aggtacgacc
    10141 tatgacttga gcaaggcaac tcaaattgtt ttgacagtag ctaaaaaagc tacgacgatt
    10201 caattaggga actatattgg acggaactct acagaagtaa tctcagaact caagcagaag
    10261 aaggttcctg agaatttgat taagatagag gaagaagagt ccagcgaaag cgaaccagga
    10321 acgattatga aacaaagtcc aggtgccgga acgacttatg atgtgagtaa acctactcaa
    10381 attgtcttga cagtagctaa aaaagttaca agtgttgcca tgccgagtta cattggttcc
    10441 agcttggagt ttactaagaa caatttgatt caaattgttg ggattaagga agctaatata
    10501 gaagttgtag aagtgacgac agcgcctgca ggtagtgcag aaggcatggt tgttgaacaa
    10561 agtcctagag caggtgaaaa ggtagacctc aataagacta gagtcaagat ttcaatctac
    10621 aaacctaaaa caacttcagc tactccttaa aagcagatgg ataatcaaaa tgagtaatca
    10681 atctttgtca tgatttcatg gcaaagattt tttttgagtc cggatttgtg atagaataga
    10741 gggagttgat aaaaggagga aagcatggaa gaatcaaaag aattaaatgc cgtcattgat
    10801 gtgattatgc tagcggggac tattctcctt aaaagtggct cagaaatcca tcgtgtagaa
    10861 gataccatga ttcgaatcgc gcattcgcag gggattgtgg attgcaatgt ccttgccatg
    10921 cctgccgcta tctttttctc tattgaaaat accaatattt cgcgcatgaa gcgcgtgacc
    10981 tcctcttctt ataacatcga aaaagtctgc gatgtgaacc agatttctcg tcagctagtt
    11041 ggggggcaga ttgacttaga aacagccttt aagcaattga cggccttgca agctcaaccc
    11101 cttccctata ctaagttgca ggtaactctg gctgcgacct ttagtgctcc tttcttttca
    11161 gttatgttta gcggaaatat ctacgacgca cttggggcag gagtggcgac cttatttggt
    11221 tttgcctttt ccctctatgt ggaaaaattt atccgaattc cctttgtgac agcctttgct
    11281 ggagcctttg tctttgggat aattgcccag ttttgggctc gctacacagg ttttccttca
    11341 acggcagatt tgattatagc tggtgcggtc atgccgtttg taccaggtat tgccttgacc
    11401 aatgcggtcc gtgatattat gaccaaccac ataaactctg gtatgagtaa gatgtttgaa
    11461 tccctgctca ttaccctcgc tttaggggca ggaacttctg tcgccttggt attgatgaac
    11521 taatatgaca ctaacaacct ttttattaca agcagtagca agttttcttg ccattatcac
    11581 ttttttaatt gtactcaatg tgcaacggtc tatgctctta cctggaggga ttttgggcat
    11641 gactgtctgg ctaatctatc tcttgctcaa ggaaccgacc aatgtcattg tagctacctt
    11701 cattgcagcc attattggtt cttgtgtcag ccagatttta agtattcttt ataagacacc
    11761 tgctgtggtc tttatcttgg ccattttggc accgctggtt ccaggttatc tctcctaccg
    11821 aacaactgcc ttttttgtga caggggacta taataaagca ctggcaagtg cgaccttggt
    11881 tgtcatgttg gctttggtaa tctctattgg aatggctagc ggaacagtga ttctcagact
    11941 gtatcattat ataaaaacac atcgagtatc gtagacttta cagaaataaa agaattttat
    12001 gaaaaatgag ataaataaat taacaacgct ttctatatgt gcgagaatac cgcacttatg
    12061 aataattgcg gctgattttg gtattcacga aagcaactta atccgtcgga gccaatgggt
    12121 tgaagtaact cttgttcaaa gtggtgttac gatttcaaga actcctctca gttctgagga
    12181 cacggtaatg attgatgcga cggaagtaaa aatcaatcgc cctaaaaaaa caattagcga
    12241 atcattctgg taaaaagaaa tgccacgcta tgaaggctca ggcgattgtc acaagtcaag
    12301 ggagaattgt ttctttggat atcgctgtga actattgtca tgatatgaag ttgttcaaaa
    12361 tgagtcgcag aaatatcgga caagctggaa aaatcttggc cgacagtggt tatcaagggc
    12421 ccatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc aagccgctaa
    12481 tagctgaaga taaagcttat aaccatgcgc tatccaagga gagaagcaag gttgagaaca
    12541 tctttgccaa agtaaaaacg tttaaaatga tttcaacaac ctatcgaaat catcgtaaac
    12601 gcttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta ggattctagt
    12661 tttgcaggaa gtctactact ttccttattg tctgtaagtc tactgacctt gttgtttatc
    12721 ccagtcatgg tttctagttc gggctcagag tttcaaagtg gatggcaaga gcatcaattg
    12781 attgctgaga aggttagtaa aacacttgac aagacatttg ataaggatgt cagagaaatt
    12841 ccgaccagtc agttttatca aaaatttgta gatgagatgg gaaggactta ctcaggaaat
    12901 ttgatcctcc aggagctgat aactgtgaat ggagcttata aagctactta tatcggtgaa
    12961 ctctctagca actaatcatt ctttaaaatg atgaccaata agaggcttga tttggtgaat
    13021 caagtctttt ttctctcttt tactgccatt tgtgataaaa tagtatagaa cgatttttta
    13081 catgaatgat aaaacagagg taaatatgac aatcggtatt gataagattg gttttgcgac
    13141 cagtcaatat gtcttgaaat tacaagactt agcagaagcg aggggaattg accctgaaaa
    13201 attaagtaaa ggactcttac tcaaggaatt gagtattgcg cccctaactg aggacatcgt
    13261 gaccttggcg gccagtgcta gtgactctat tttaactgag caagaaagac aagaagttga
    13321 catggtcatt gtggctaccg agtcaggaat tgaccagagt aaggctgcgg ccgtctttgt
    13381 gcatggcttg ctgggcatcc agccctttgc tcgtagtttc gagattaaag aagcctgcta
    13441 cggagcgact gctgccctcc attatgccaa attgcatgtg gaaaattctc cggagtccaa
    13501 ggtcttggtc attgccagtg atattgccaa atacggtatt gaaactccag gagaaccaac
    13561 tcaaggtgct ggaagtgtag ctatgttgat tacacaaaat ccacgcatga tggcctttaa
    13621 taatgacaat gtagctcaga cccgtgacat catggatttc tggcgaccaa attactcgac
    13681 aactccttat gtaaatggtg tctattctac ccaacaatac ttggatagtt tgaaaacgac
    13741 ttggcttgaa tatcaaaaac gctaccagct tactttggat gattttgcgg ctgtttgttt
    13801 ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa aaaatcatgg ataagagcct
    13861 gcctcaagag aaaaaagacc tcttacaaaa gcattttgac cagtctattc tctacagtca
    13921 aaaggtgggg aatatctaca caggttcact tttccttgga cttttgtctc tcttggaaaa
    13981 tacagatagc ttgaaagctg gggataaaat cgccctttat agttacggaa gtggagctgt
    14041 ggctgagttc ttcagtggtg aattggttga aggatatgaa gcttatttgg ataaagaccg
    14101 cttgaacaag ctcaaccaac gaactgccct atccgttgca gactatgaaa aggtcttttt
    14161 tgaggaagta aacttggatg aaacaaactc tgcccagttt gctggctatg aaaatcaaga
    14221 ttttgccttg gttgaaattc tcgaccacca acgccgttat agcaaggttg aaaaataatg
    14281 aagataagtt ggaatggatt ttctaaaaaa tcataccaag agcgcctcga gctgttaaaa
    14341 gctcaggcgc tccttagtcc tgagagacaa gctagtctgg agaaggatga acagatgagc
    14401 gtgactgtgg cagaccagct gagtgagaat gtagtgggaa ctttttctct gccttattca
    14461 ctggttccgg aggtacttgt caacggtcag gaatacaccg ttccctatgt gacagaagaa
    14521 ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca tcaagcgtgc aggtggtttt
    14581 actgcacaag tccatcagcg acagatgatt gggcaggtag cactttatca agttgctaat
    14641 cctaaactag cgcaagagaa gattgccagc aagaaagcgg agctcttgga gcttgccaat
    14701 caagcctatc cttctatcgt taaacgtgga ggtggggcgc gtgatctgca tgtcgagcag
    14761 ataaaaggtg aaccagactt tctcgttgtt tatattcatg tcgataccca ggaagccatg
    14821 ggtgccaata tgctcaacac catgctggaa gccttgaaac cagtcttaga agaactcagt
    14881 cagggacaga gtctcatggc aatcctgtcc aactacgcga ccgattctct ggtgactgca
    14941 agctgtcgca tcgcctttcg ctacttgagc cgccaaaagg atcaaggacg agagattgcg
    15001 gagaaaattg cgttggctag tcagtttgcg caggctgatc cttaccgagc tgctactcat
    15061 aataaaggaa tttttaatgg tattgatgcg attttgattg ccactggtaa tgactggcgt
    15121 gccatcgaag ctggggccca tgcctttgcc agtcgagatg gacgctatca aggtcttagc
    15181 tgctggacgc tggaccttga aagagaagaa ttggtcggtg agatgaccct gcccatgcct
    15241 gtagcgacta agggtggctc tatcggcctc aacccacgtg tagctctcag tcatgatcta
    15301 ctaggaaatc cttctgccag agaattagcc cagattatcg tgtccatcgg tcttgcccaa
    15361 aattttgcag ccctcaaagc cttggtaagt acgggcatcc agcaaggcca catgaaacta
    15421 caggccaaat ccctagctct cctagctggg gctagtgaat ctgaagttgc tcccctagta
    15481 gagcgcctca tctcagataa aacctttaac ctagagacag cccagcgcta tctcgaaaat
    15541 ttaagatcat aaaaaactca gacgaatcgg tctgagtttt cttgtgttta aatacttttt
    15601 cctggtaata gtgtaactgg taagaagtaa ccagttgtgg cgacttcctt gccttcaatc
    15661 ttttgcaaga gaagatcaat agtgagacaa gcaatctctt ccaaaggttg cttgatagta
    15721 gccaattgag ggtagtaatt ttcgataaag taggtcccat catagccgat gaccttgagc
    15781 tcttttggga cagaaatgcc caattcttga gcgattttaa tgaccagaat agctgtcaaa
    15841 tcatccgaag caaaaatggc atctggtttt tcccgggtca agatattctt gatttccatt
    15901 tcttttctga cgggagaaaa gtcactggaa acattgataa taggagcttt tgggagtacg
    15961 gatgcaaaac cagcgtggcg cagtccggtt ggcgaattgg aattgtcatt ccctgtaatc
    16021 atgatgatag actgggcacc tgtcttgacc aaggtttggg cagcaagaac cccaccagca
    16081 tagttgtcag aggagacgac agggatgtct ggcgataggt ttcgatcaaa ggaaataatc
    16141 ggcgctgtca cacgattgta gtcttcgatt cctaggttgt gactaccaga aatgatgccg
    16201 tccacctgat tggcttccaa catttcgatg tattcgcgtt ccttctcaga atcatgttca
    16261 ctgttgcaga tgatggtctt gtaaccattt ttgaagagtt gatgttccaa tttatcaatc
    16321 aattctgcat agaaaacatt ggaaatattg gggaaaatca agccgattaa cttagctgat
    16381 tttccttgca gactacgagc caggttgttg ggtttatagc ccaattctcg catggcttca
    16441 ttgacttttt ggatggtttt ctcagataga tatccttttt tattgataac ccgagaaacg
    16501 gtagtaggac tgacgcctgc aagtttggcg acatcagtta gttttgcgac cataatctaa
    16561 ttcatagtaa gttccagttg ggtttccaga tttgatcagg ataccatttt ggtccgcatg
    16621 tgggaagaca cgaccagaaa atactttttc tcctttattg atgaaaattt caaagacaga
    16681 gttatcgatg aagattgtag cagtagtagc ctgattctcg atagggcaag aacgagttgt
    16741 cccaaattct tgggcatact gctctccagc ctggctacga tccactgtca cttgaccgtt
    16801 tacaaggtca aagttgattg aaagtccctt accttcttta tcagcaagta agacaatctc
    16861 gctctggcta ttagcttcca agttgagttc aagttcgtaa gtgttcttgg tttgggaacg
    16921 gtttgagaag gcttcttcag aagcacgaag gtccttaata gcagcgactg gatactggta
    16981 gagcttgtcg tctttgatag tgagttcctt gaccaaagag aaggttcctt ggtggtcaaa
    17041 atggtcagat gggtaagaaa catctggcaa accaagccag ctaactgcta gagcacgccc
    17101 atcaggagcg ttgaaggctt gagttgcata ggcttcgaaa ccgtaatcca tgttttgaag
    17161 ttgagacaca tctaccattt tggcattttt agggtcaaag gaagccccaa tcttatacat
    17221 atttggaaag atattatcgt agtctagaac tttcttatcc aatccttgtg gacagtagag
    17281 aaggacagga tgttcctcta caaagaccag attaggacat tccatcatgt aggcagtacg
    17341 gtcgttagca aagtcaaggt cgccaactgc ttgccagttt gtgtagtcgt tattgacagc
    17401 cttgtagaga cggacgaagc cttttttctc caagtcctgt ccaccgacga cagcatagta
    17461 ttgaccttta aagttaaaaa tttgtggatc gcggaagtgg tcagtagagt ctgctggctg
    17521 gtcaatcaag atcttgtcaa tctttgtaat cttaccctcc ttgtccatca aagcaccgat
    17581 ctggtatggg tgacggatcc agttttcatc gcgaacattt cctgtataaa ataggaataa
    17641 gttatcgcca aattgcatgg cagaaccaga gtaggcaccg tggctatcta atggagtatc
    17701 tggtaaaact ttgattccag tttctctaaa gtgaaccaaa tcatcacttt ctagctgtgc
    17761 ccaagatttc aaaccgtggg ctgcaccaaa aggaaaattc tggtaaaaga ggatccactt
    17821 gccatcaaag taagaaaagc catttgggtc gttgagaagt cctgtttttg gctcaacatg
    17881 gtaatgagta tgccatggag attgtgccat attttccttt atatgttgaa tttcttcttg
    17941 cgtccaatct tgataaagtc tgtaacgacg ctcagttgtc cattccattc attcctccaa
    18001 aaatcttatc acttttaata gtaactgttt tcgataaaaa atgcaagcct tttatattaa
    18061 aaaagagaaa aaactgtcaa acgattatca taaaataaat acaggaaatc aatcaaattt
    18121 ttacgaaaat gtgaaagata atgaaataaa agacttttta accaaggttt caaacttatt
    18181 tttcaagaaa ttcctgatga aacagtcaaa aacaatcaat ctaaagcttg cccactaagt
    18241 agatagaata ttttttatgc aaaacgcttg acatattttt aaaacatgat aaaataatag
    18301 tcgtaagggc gaataaaatc gctttcaaac aagaacaaaa tgttatataa ggagattttt
    18361 gcaaatgaac aatcaggaaa ttgcaaaaaa agtcatcgat gccttgggcg gacgtgaaaa
    18421 tgtcaatagt gttgcccact gtgcgactcg tttacgtgtc atggtcaaag atgaagagaa
    18481 aatcaataaa gaagtgattg agaacttgga aaaagttcaa ggtgctttct ttaactcagg
    18541 gcaataccaa attatctttg gtacaggtac agttaacaaa atgtacgatg aagttgttgt
    18601 acttggctta ccaacatcat ctaaggatga catgaaagca gaagttgcta aacaggggaa
    18661 ctggttccaa cgtgctatcc gtactttcgg tgatgttttc gttccaatca tcccagttat
    18721 cgtagcgaca ggtctcttca tgggtgtgcg tggtcttttc aacgctcttg aaatgccact
    18781 tccaggtgac tttgcaactt acacacaaat cttgacagat acagccttca tcatcttgcc
    18841 aggtttggtt gtgtggtcaa ccttccgtgt atttggtgga aatcctgccg ttggtatcgt
    18901 tcttggtatg atgcttgtct ctggctcact tccaaacgct tgggcagttg ctcaaggtgg
    18961 tgaagtaaca gcgatgaact tctttggttt catccctgtt gttggtttgc aaggttccgt
    19021 tcttccagcc ttcatcatcg gggttgtcgg agctaaattt gaaaaagctg tccgcaaggt
    19081 tgttccagat gtcattgacc tcttggtaac accattcgtg acacttttgg tcatgtctat
    19141 ccttggactc tttgtcattg gaccagtttt ccacgttgtt gaaaactaca tccttattgc
    19201 tacaaaagcg attcttagca tgccatttgg tcttggtggt ttcttgattg gtggggttca
    19261 ccaattgatc gtcgtgtcag gtgtgcatca catcttcaac ttgcttgaag tgcaattact
    19321 tgctgctgac catgctaacc cattcaacgc tatcatcaca gctgctatga cagctcaagg
    19381 tgctgctact gttgcggttg gtgttaaaac aaaaaatcca aaactgaaaa cacttgcttt
    19441 cccggctgct ctttctgcct tcctaggtat tacagagcct gctatcttcg gggtgaactt
    19501 gcgcttccgt aaaccattct tcctttcatt gattgctggt gcaatcggtg gtggattggc
    19561 ttctatcctt ggacttgctg gtactggtaa tggtatcacc atcatccctg gtacaatgct
    19621 ttatgttggt aacggacaac ttccacaata ccttcttatg gtagctgtat catttgccct
    19681 tggttttgct cttacttaca tgtttggtta cgaagatgaa gtagacgcaa ctgcagctgc
    19741 aaaacaagct gaagtggctg aagaaaaaga agaagttgcg ccagcagctc ttcaaaatga
    19801 aacacttgta actcctatcg tcggtgatgt tgtcgctctt gctgatgtca atgacccagt
    19861 cttctcaagt ggagctatgg gacaaggtat cgctgtgaaa ccaagccaag gcgtggtcta
    19921 tgcaccagct gatgctgaag tttcaattgc ctttccaaca gggcacgctt ttggtttgaa
    19981 aacaagaaat ggtgctgaag ttttgattca cgttggtatt gacactgtat ctatgaacgg
    20041 tgacggtttt gaagcaaaag ttgctcaagg tgataaggtg aaagctggcg atgttctggg
    20101 aacatttgac tcaaacaaaa tcgctgcagc tggacttgat gatacgacaa tgcttatcgt
    20161 tacaaataca ggtgactacg cttcagtagc tccagtcgca acaggttcag ttgcgaaggg
    20221 ggatgctgtg atcgaagtga aaatctaatc aatcctctct aatgtgaaaa cgaacaaatg
    20281 acatgtttgt tcgtttttat tagatagtaa gatttacaga ggaaaatcta aaaaatagag
    20341 acatttagac tttcgaagta tgctataata aagaaaataa aaacaagagg tttatcatga
    20401 caaaattata tggaagcttg gaagcgggcg gtacaaagtt tgtctgtgct gtcggtgatg
    20461 aaaactttaa cgttgtagaa aaaacacaat ttccaacaac aactccaatc gaaacaatcg
    20521 ataaaaccat tgagttcttc tcaaaattcg ataaccttgc tggtcttgca gttggttcat
    20581 ttgggccgat tgatattgac aaaaactcaa aaacttatgg ctttatcacg acgactccaa
    20641 aaccaagctg ggcaaatgta gacttgcttg gtgcccttcg tcgcgcccta aacgtgccaa
    20701 tgtacttcac aacagacgta aacagctctg cttacggtga aatggttgcc cgtaacaatg
    20761 ctggtggtcg tatcgaaaac ttggtttact acacaatcgg tacaggtatc ggtgcaggcg
    20821 tcatccaacg tggtgagttt atcggtggtg tgggtcaccc tgaaatgggt cattattatg
    20881 ttgctagaca cccaatggat attgaaaaag agtttaaggg tgtttgtcct ttccataagg
    20941 gatgtctaga aggttatgca gctggtccaa gtttggaagc tcgtacaggt gtacgtgggg
    21001 aaactattga actcaacaac cctgtttggg atgttcaagc ctactatatc gctcaagctg
    21061 cggttaatgc gacagtgact ttccgcccag acgtgattgt ctttggtgga ggggtcatgg
    21121 ctcaacaaca tatgctggac cgtgtccgtg agaaatttac atctcttctt aatggttacc
    21181 taccagtacc agatgtgcgt gactatatcg tgacgccagc agtcgcagga aatggttctg
    21241 ccacacttgg gaactttgtt cttgcaaaag aagtttcaaa ataaagcaca aaatccgctt
    21301 gggaaaccaa acggattttg tggttgaaaa caatattttt gagcctttcc ttaagtgatt
    21361 acggacggta gcgactttct tcgaaattcc atacctaaac tttgagacac taggctcaaa
    21421 gtttccgaat acctgaaacc attagatttc aggtgtttct atcacggcgg aaaggctagg
    21481 taagtcctcg cctcactatc gaaaaatatg catgatttcc ataccaaagt atatttagta
    21541 tcaagctata gttaatctac gctttaaaaa tccacttggg aaaccaaacg gattttttac
    21601 gtgtcaaagc atttgccaga aaaagtcaat aatataggtc agaccgtagg tataaaccac
    21661 gagggtaaag ggtttggtca gaatgatgat ggtcatgtag cgcttgaaac tcatcttggt
    21721 cagggcagcc agcatacaga gaaagtcagc tgggctaatg ggccaaatca tcataaaaat
    21781 aaagaagcgg tcaaaacgat tgcccttatc tagccagccg atgtacttgt cgtaggtgcg
    21841 cttgctgacg acagactgga caaaggcagc tccgtatagg cgcactagat aaaagataat
    21901 ggcacagcca atcacgatgc cgatatagtt gtagatagtc ccgatgatgt gcccgtagat
    21961 aaagacccca gccaccgagg tcaaggcccc tggaatgata gggacgacag tctgtaaaat
    22021 ctgtaaaaag ataaagagag gtggacccca gatgcctgcc tgctggataa aggcagagag
    22081 ggtttccttg gattgtaaaa tcccagcctg ataagcccaa atacagaaaa tcaaactccc
    22141 aaccccaccg acaatcgatg agatattgat aactcgctgc agaaggggag aaacagcttt
    22201 catttgttta tcctgtgaca tgtaaactcc tcatagatag tatatttcta ctataccata
    22261 ttttggagga gaaaggggga atgagtcttt tttgataagg aatagaaagt gaatagccct
    22321 tcgagactta gaatgggtct gtcaactaaa ggttatatgc attctaggtt tcgaataatc
    22381 gcaattccat aaatttaaaa gcattctaag tttcgaatag cttatctgag ataattttga
    22441 ggcattcgcg ctttcgaata gtcattttcc ctaaagttta gatgtattct gaagctagaa
    22501 agactaaaat ctaaaagtag taagagtctc tctctgatgg acgtaattta tggctagtat
    22561 gaatcctttg aattgttagt taattttaat attaatcagt tctgaaataa ttactaaata
    22621 tagttagatg gtgaattaat tattgctaaa tttcaagttc aagttagtca tccagaagtc
    22681 ttctctgggg gacttgtagt tcaagcattt tttaggatag ttgttaatcc acttttcgat
    22741 gaatgcgact tcctttgtag tcgttttctt agttccctga ggtaaccatc tatgaatgaa
    22801 cttgttgtga tttttattag atcctatagt ggtgtgcata atagatataa tagattgaaa
    22861 ctagaatagt acgcatctac ttctaaaaca ttgttagaaa tcgatttgac tgtcccgatc
    22921 tatttgtcct gtttttattt cattttacta tataatcctt agaaaacata tcggacaagc
    22981 ggttgaattc cgttccgtcc attagtagat aaaggattac tccttcttga aatgacagat
    23041 gaacttgttt cttataaaaa tgttgtctga aactattcgc ttttttccag aagttttaga
    23101 ggaagaaaac tttatgagga aaaaggactt actcaaataa caattcagga ttaaaaatag
    23161 acagttgagg agcggaaggt ataaattaag tttgctgctg tataatggat ttatcactaa
    23221 tactcttcga aaatctcttc aaaccacgtc agcttcgcct tgccgtacgt atagttactg
    23281 acttcgtcag ttctatccac aacctcaaaa cagtgttttg agctgacttc gtcagtttta
    23341 tctgcaacct caaagctgta ctttgagcag tctacggcta gcttcctagt ttgctctttg
    23401 attttcattg agtataaaag tgctccaggc catattttac acagcaatag tcttctaaaa
    23461 atggacaaaa aacattgtaa aggctatcaa aaaggagtat aatgagtgca agaaatttcg
    23521 gaggtgaaag atgctagaag taagaagtct agagaaaagt tttggatcca agcaagtttt
    23581 gtttggtatt gactttcaag cgcgaccagg tcgtattttg ggactagtcg gaaaaaatgg
    23641 tgctggaaaa acaacgattt tccatagtat tttaaaattc ctagaatatc agggagaaat
    23701 cggtctggat ggtcaggata ttcgtcagga gatctatgct cggattggtt atctgcctga
    23761 agaacgcagt ctcatgccta aattgacagt tcttgaacaa gttcgctact tggcgactct
    23821 aaaaggcatg gatgccaaag aagtcaaaga aaaactccct caatggatga agaggttgga
    23881 agtaaaagga aagctgacag ataaaatcaa gagtctgtca aaaggaaatc agcagaagat
    23941 tcagctcatt attactctga ttcatgaacc agacctgatt atcttggatg agccttttag
    24001 tggattggac ccagttaata cagaattgct caaacaagtc atttttcagg aaaaagagcg
    24061 cggagcaacc attatctttt ctgaccatgt catgaccaat gttgaggaac tttgtgacga
    24121 tattctgatg attcgagatg gccgtgtggt cttgcacgga ccagttcagg atgtccgcaa
    24181 tcaatacggg aaaacgcgtc tctttgtttc aagtgaacga agcaaggaag aattggaaaa
    24241 tcttcctcat gtcaaacagg tgagcttgac caaacaaggc agttggaaat tgattttgga
    24301 ggatgagagc gctggaaggg aactcttccc aatcttgact caaggtcaat atatcgcaac
    24361 atttgaccaa caagcgccaa ctatcgatga aatctttaaa ctagaatcag gagtggaagt
    24421 atgagaaata tgtgggttgt aatcaaggaa acctatcttc gacatgtcga gtcatggagt
    24481 ttcttcttta tggtgatttc gccgttcctc tttttaggaa tctctgtagg aattgggcat
    24541 ctccaaggtt cttctatggc taaaaataat aaagtggcag tagtgacaac agtgccatct
    24601 gtagcagaag gactgaagaa tgtaaatggt gttaacttcg actataaaga cgaagcaagt
    24661 gccaaagaag caattaaaga agaaaaatta aaaggttatt tgaccattga tcaagaagat
    24721 agtgttctaa aggcagttta tcatggcgaa acatcgcttg aaaatggaat taaatttgag
    24781 gttacaggta cactcaatga actgcaaaat cagcttaatc gttcaactgc ttccttgtct
    24841 caagagcagg aaaaacgctt agcgcagaca attcaattca cagaaaagat tgatgaagcc
    24901 aaggaaaata aaaagtttat tcaaacaatt gcagcaggtg ccttaggatt ctttctttat
    24961 atgattctga ttacctatgc gggtgtaaca gctcaggaag ttgccagtga aaaaggcacc
    25021 aaaattatgg aagtcgtctt ttctagcata agggcaagtc actatttcta tgcgcggatg
    25081 atggctctgt ttctagtgat tttaacgcat attgggatct atgttgtagg tggtctggct
    25141 gccgttttgc tctttaaaga tttgccattc ttggctcagt ctggtatttt ggatcacttg
    25201 ggagatgcta tctcactgaa taccttgctc tttattttga tcagtctttt catgtacgta
    25261 gtcttggcag ccttcctagg atctatggtt tctcgtcctg aagactcagg gaaagccttg
    25321 tcgcctttga tgattttgat tatgggtggt ttttttggag tgacagctct aggtgcagct
    25381 ggtgacaatc tcctcttgaa gattggttct tatattccct ttatttcgac cttctttatg
    25441 ccgtttcgaa cgattaatgg ctatgcggag ggagcggaag catggatttc acttgctatt
    25501 acagtgattt ttgcggtggt agcaacagga tttatcggac gcatgtatgc tagtctcgtt
    25561 cttcaaacgg atgatttagg gatttggaaa acctttaaac gtgccttatc ttataaatag
    25621 aagagccttg cgaaagcgag gtttttaaag gtgaaaaggg tggaatcacg aacctaatta
    25681 tgtacacatt atgtaaacag gttgcttgaa aactcaattg tatagtgaac tgaatctgga
    25741 ataggataat attacttcta aaacattctt ataaattgat ttgaattcca aaatcccatc
    25801 gttccgttct tatttcattt tgcgatatag tgaaaggaaa taagtcagct cacaaaaaac
    25861 gcataatatc aaggattttt aacacttgat actatgcgtt ttctaattgt aaagactttt
    25921 tgcctggtct cttttgttct atgagtatgt tacatatcta ggtaaaaatt atttaaagca
    25981 aattaacctt atttctcaag atgtagtagg ttccgagata aaagatagct atgaatatga
    26041 gttcttcaac aatggctata cctgctccca tatagaaatg gtcattgagt cctaccagtg
    26101 aattgacata gaaattagaa ctaagattga agaaaagttc aataaatcca atgacgattt
    26161 ggataccaat gtagactgca acagcgagtg ctgtacggta ttcattgaaa agctgtccaa
    26221 tggaaatagc caggtagatg cagaggattc ctgaaatagt atttagtagg aaggatatac
    26281 ctgtaagaaa gatctgaggg agatgtgttt ctacaaatgt aatcacataa gaaagaggaa
    26341 tccattctgg agctgttaaa gccagaataa taacagcact tagagccaat acagcggtgc
    26401 taatcaatga ccagataaag gcaccgatta gtttggctgt gatgatatgg tgttcagaaa
    26461 ctggcaaggt caaagtcaga tagccttgtc ggtcgtagac actacctttg aagcgtttaa
    26521 taatcaagaa aatggttgaa atcgcaagtg taagcatcaa gccaccaaag actgtagcta
    26581 gaaaaagtag catagtagcc tgactttctt tgtaaggtag atttttaaag ccttgtgtct
    26641 gtattccgat gagggcagaa aggactagca cggctgcgta gagggctaaa taccacttgt
    26701 taacattttt aaattcgtag tgaactaaat tccaaaacat aaataatctc ctttgcttag
    26761 gccttaaatt cctgacggaa gagttggtca atggattcac ctgactcgta gcgaatatca
    26821 tctacatttc cttgacggac gacttttccg tcttttagga agacaatttc atccaagatt
    26881 ggctcgatat cagaaatcaa gtgggtagaa atcaaaacgg tagaagttgg tgagtagttg
    26941 ttgataatgg tattgaggat ataagcacgg gctgctggat ccaccccacc aatgggttca
    27001 tccaaaacat agagacgagc atcacggctc ataaccaaaa tcagttgaac cttttctttg
    27061 tttccttttg atagtttctt gagacgacta ttttcatcaa tgcccaggtc tgcaagtaga
    27121 tgatgagcgc gttcaagatt gaaatcttta tagaaggtct tgaagtaggt tagggcttct
    27181 ttgaccttca tttgctcatt gagataggtc gtatcaggca aataagctac aacggccttg
    27241 gttgctgggc ttgggtccat gtcgttgatg aggacacgtc cttgatctgg ttgtaagagg
    27301 ccattaatta gtttaatcag ggttgttttt cctgagccgt ttggcccaag aaggccgaca
    27361 atttttccag ctggaatgtc aagagaaaca ttttcaaggg ctggtgttgc tccatatgat
    27421 ttggatacat tttcaaatgc tagtaatgac ataggcttaa actcctttaa tataatcact
    27481 gactacgcct ggtagttctt ctttttcata gccaaaatgg gtcatggagg aaacgaagtg
    27541 ttccaattct tcttctgata attgtttgcg tgactgagcg attagctcct tatccttagt
    27601 cacaaatcgt ccagttgttc gcttgctgta gacaaatcct tctcgttcaa ggtctgataa
    27661 ggctctttgg atggtattgg gattgacacc agcctcgcta gctagctccc tcacggttgg
    27721 aagttgttga ttgggttcca gtgtatggga aacaatctga agcttgattt tctccataat
    27781 ctgtaaatag atgggttttt tgttgtcaaa tgtccaggac atcttagtct cctttctctt
    27841 atccttttgt cttaattaaa taatacaaca aaacaaaaaa cttgtcaagc aaaaagaaga
    27901 attgttttgg gaatcgctta aaaaatggta taatgaaaag aaaacgataa ggagggaaag
    27961 gatgcgttgt ccaaaatgtg gggctaccaa gtcaagtgtt atcgatagtc gccaagcaga
    28021 agaagggaac accattcgta gaagacgaga gtgcgacgag tgccaacacc gttttacaac
    28081 ctacgaacga gtagaagaaa gaaccttagt ggttgttaaa aaagatggca cacgggaaca
    28141 attctccaga gataaaatct ttaatgggat tatccgctca gcccagaaac gtcctgtgtc
    28201 aagtgatgaa atcaacatgg tagtcaatcg tatcgaacag aaactccgtg gtcgaaatga
    28261 aaatgaaatt caaagtgagg acattggttc acttgtcatg gaggagttgg ctgaattgga
    28321 cgagattacc tatgtacgtt ttgctagtgt ctatcgtagt tttaaggatg tcagtgagtt
    28381 agagagcttg ctccaacaaa tcacccagtc ctctaaaaag aaaaaggaaa gataaatgaa
    28441 gccaattgac cgtttttctt atctaaagaa taatcgggtg tcgcaagata cctcatctct
    28501 ggtacagtgc tacctcccga ttatcggtca ggaggcactg agcctttatc tttatacaat
    28561 cagtttttgg gataatggta gaaaggaata tcttttttca agtatcctca atcatctcaa
    28621 ctttgggatg gatagactga taaaatcatt gaaaatctta tctgctttta atctcttgac
    28681 cctctatcaa aagggggatg tttatcagct agccctccat gctcctctat ctagtcaaga
    28741 cttcttggag catcctgttt atcgcagact cttagagaaa aagattggcg actctgctgt
    28801 ggaggatttg aaagttgaaa gtgctgatgg tgaagaaata cctgtctcac tcaatcaagt
    28861 ctttccagaa ttggcagaac taggcagtca agaagacctt ggtctcaaga agaaagtggc
    28921 caatgatttt gacttggaac attttcgcca gctgatggct cgagatggac ttcgttttgc
    28981 ggatgagcag tccgatgtct taaacctctt tgctattgcc gaggagaaga aatggacttg
    29041 gtttgaaacc tatcaattgg ccaagtcaac agctgtttct caggttattt caaccaaacg
    29101 catgcgtgaa aaaattgctc aaaaaccagt ttcctctgac tttagtctta aggaaacaac
    29161 cattatcaaa gaagccaaaa gtaaaactgc cctgcagttc ttggcagaaa tcaagcaaac
    29221 acgcaaggga accattaccc aaacagaaag agaactcttg caacagatgg ctggcttggg
    29281 cttgctggac gaagtcatca atatcattct tttattgacc tttaataagg tcgattcggc
    29341 aaatatcaat gagaaatatg ccatgaaggt agccaatgac tatgcctatc aaaagattca
    29401 ttcggcagaa aaggcagtct tgcgcatccg tgagcgaggg cagaaaacaa aaacacaaaa
    29461 acagaatcag actgccccag caaaaaccaa tattcctaaa tggagtaatc ctgaatataa
    29521 aaatacgtca tccgctgagg aattagaaga gatggaacgc caaaccctag aattattagc
    29581 aaaattagat aacggaggtg attagatgga aagtgtcgga gatgtactca aacgtcaacc
    29641 aagtcgtttt cactatcaag atttagttca gaaaatcatg aaggatcctg atgttgcggc
    29701 ctttgtccag caagaatccc tcaatcagga cgagttgaac cgtagtattt ccaagtttaa
    29761 ccaatacatc actgagagag ataaattcct ccgaggagat acagattata ttgccaaagg
    29821 ctacaagcct atattagtca tgaaccatgg ctatgcggat gtttcttatg aagaaactcc
    29881 tgaactaatc gcagctgaaa aagaagcggc tatcaagaaa cgtctcaact taattaattt
    29941 tccatctagc ctgaaaaatg tcagtttttt agatgtttat cgtgatgatg ttcagcgctt
    30001 aactgttcta aaaagaatga tagaatttgt taacgattac cccaataatt tgaaaggtct
    30061 ttacttatat ggagactttg gtgtgggtaa aagtttcatg gtggctgccc tagctcatga
    30121 tttatcagaa aaacgtggtg tatcatccac tctcctccac tatcctagct ttgtcattga
    30181 tgtcaaaaat gctatcggtg atggcaatgt taagacctta gtggatgaga ttaagctttc
    30241 tgaagtcctg attttagatg atattggtgc cgagcaatcc accgcttggg tgcgtgatga
    30301 aatcctgcag gtcattctcc aatatcggat gcaggaaaat ttaccgacct ttttcacctc
    30361 taacttcaac tttgaagatt tggagaagca tttcgctaaa gggaaaaatg gaaatgacga
    30421 aacctgggaa gccagacgtg tcatggaacg catccgttat ttggctgagg agactcgttt
    30481 agaaggagta aaccgtcgat gacagaaacc attaaattga tgaaggctca tacttcagtg
    30541 cgcaggttta aagagcaaga aattccccaa gtagacttaa atgagatttt gacagcagcc
    30601 cagatggcat catcttggaa gaatttccaa tcctactctg tgattgtggt acgaagtcaa
    30661 gagaagaaag atgccttgta tgaattggta cctcaagaag ccattcgcca gtctgctgtt
    30721 ttccttctct ttgtcggaga tttgaaccga gcagaaaagg gagcccgact tcataccgac
    30781 accttccaac cccaaggtgt ggaaggtctc ttgattagtt cggtcgatgc agctcttgct
    30841 ggacaaaacg ccttgttggc agctgaaagc ttgggctatg gtggtgtgat tatcggtttg
    30901 gttcgataca agtctgaaga agtggcagag ctctttaacc tacctgacta cacctattct
    30961 gtctttggga tggcactggg tgtgccaaat caacatcatg atatgaaacc gagactgcca
    31021 ctagagaatg ttgtctttga ggaagaatac caagaacagt caactgaggc aatccaagct
    31081 tatgaccgtg ttcaggctga ctatgctgga gcgcgtgcga ccacaagctg gagtcagcgt
    31141 ctagcagaac agtttggcca agcagaacca agctcaacta gaaaaaatct taaacagaag
    31201 aagttattgt agaaagtgag aaattatggc cctaccaact attgccattg taggacgtcc
    31261 caatgttggg aaatcaaccc tatttaatcg gatcgctggt gagcgaatct ccattgtaga
    31321 agatgtcgaa ggagtgacac gtgaccgtat ttatgcaacg ggtgagtggc tcaatcgctc
    31381 ttttagtatg attgatacag gaggaattga tgatgtcgat gctcctttca tggaacaaat
    31441 caagcaccag gcagaaattg ccatggaaga agcagatgtt atcgtttttg tcgtgtctgg
    31501 taaggaagga attactgatg cagacgaata cgtagctcgt aagctttata agacccacaa
    31561 accagttatc ctcgcagtca acaaggtgga caaccctgag atgagaaatg atatctatga
    31621 tttctatgct ctcggtttgg gtgaaccact gcctatctca tctgtccatg gaatcggtac
    31681 aggggatgta ctagatgcga ttgtggaaaa ccttccaaat gaatatgaag aagaaaatcc
    31741 agatgtcatt aagtttagct tgattggtcg tcctaacgtt ggaaaatcaa gcttgattaa
    31801 tgctatcttg ggagaagacc gtgtcattgc cagtcctgtt gctggaacaa ctcgtgatgc
    31861 cattgatacc cactttacag atacagatgg tcaagagttt accatgattg atacggctgg
    31921 tatgcgtaag tctggtaagg tttatgaaaa tactgagaag tactctgtca tgcgtgccat
    31981 gcgtgctatt gaccgttcag atgtggtctt aatggtcatc aatgcggaag aggggattcg
    32041 tgaatacgac aagcgtatcg ctggatttgc tcatgaagct ggtaaaggga tgattatcgt
    32101 ggtcaacaag tgggatacgc ttgaaaaaga taaccacact atgaaaaact gggaagaaga
    32161 tatccgtgag cagttccaat acctgcctta cgcaccgatt atctttgtat cagctttaac
    32221 caagcaacgt ctccacaaac ttcctgggat gattaagcaa atcagcgaaa gtcaaaatac
    32281 acgtattcca tcagctgtct tgaacgatgt catcatggat gccattgcca tcaacccaac
    32341 accgacagac aaaggaaaac gtctcaagat tttctatgcg acccaagtgg caaccaaacc
    32401 accaaccttt gttatctttg tcaacgaaga agaactcatg cacttttctt acctacgttt
    32461 cttggaaaat caaatccgca aggcctttgt ctttgaggga acaccgattc atctcatagc
    32521 aagaaagcgt aaataaaaaa gtagaatctg gaatgacatt tccagattct tttgatataa
    32581 taaaataata gaaaacgcta tcaaaagaag gagggggatg tcggtgatgg aacatttgtt
    32641 taaattctta cttttagcac cgtactttta ttttgataac tggattgaaa aggccaacag
    32701 aaatagtaag ttttttccaa ttttttatta tttttactgg atttacatcc ccttctattc
    32761 tctttttagc cttgcttgga cagttgtttc agttctgttt ttcaataccg tcttgagaaa
    32821 tgtgacagat atcaagttat ggggcatttg gtttcttttt attctgctag ctattggtat
    32881 gaattggtta acttattcct gtttcaaaga aatgtttcgc ttgagacagg aactagggaa
    32941 gtctaagggt ggaaggcatt gatttatatc ggtttctatt tgtaggaggt ggcttatggt
    33001 acctctaaaa tcatttatta cacgctattc caaggtttat attggtaata acatttaata
    33061 gaacgaaact aaagaaaaca atttaaaaaa ggaggcttgt gatggaacac ttgtttaaaa
    33121 tgataatctt attaccctgt ttttactttt tcagctggat tgacaaggat aatagagaaa
    33181 gtaaattttt cccaattttt tactattttt actggattta catccccctc tatgctcttt
    33241 ttagcctttc ttggacagtt ttttcagttc tgtttttcaa tatcgtcttg agaaatttga
    33301 cagatatcaa gttatggggt atttggctat tattactact tatcgctttt gctagtgact
    33361 ggttagacta tatctgtttc aaaaaaatgc ttgacttgag acgggaacta gggaagtcta
    33421 aaggcggaag gcattgattt atactcttcg aaaatctctt caaaccacgt caacgtcgcc
    33481 ttggattata tatgtaactg acttcgtcag tcttatctac aacctcaaag cagtgctttg
    33541 agcaacttgc ggctagtttc ctagtttgct ctttgatttt cattgagtat tatattactt
    33601 tctatttgta ggaggtggct tatgaagatt cctctcttaa ctttggcaag gcataaattt
    33661 gtttatgtct tgcttacttt gctttttctt gctttggttt atcgtgatgt tttgatgact
    33721 tatttctttt ttgatattca tgcgcccgat ctagctaaat tcgatggaca agcaattaaa
    33781 aatgacttat taaaatcagc attagatttt cgtattctcc agttcaatct aggtttttat
    33841 caatcattta ttattccaat catcattgtt ttgctaggtt ttcaatatat tgagctgaaa
    33901 aataaagttt tacgattgag tattggaaga gaagtgagtt atcaagggtt aaaaagaaag
    33961 ttgactttgc aagttgcaag tatcccttgt ttgatatatt tagtgactgt gctgataatt
    34021 gcaattgtaa cctatttctt tgggactttt tctcctcttg gatggaattc tctattttct
    34081 gatggaagtg gtttacaaag actcctagat ggagagataa aaagctattt gttctttact
    34141 tgtgtcctac taatcggtat tttcatcaat gcaatctatt ttttacaaat agttgattat
    34201 gtggggaatg tgactcgttc ggcaatcacc tatttgatgt ttctttggct tggttctatg
    34261 ctgctctata gtgccttgcc ttactatatg gttcctatga cgagtttgat gcaagctagc
    34321 tatggggatg taagtttgat gaaactcttt actccttata tcctttatgt tgtcccttat
    34381 atggtgcttg aaaaatatga agataatgtt taagaatttt aacaatattt ggctaaagag
    34441 aaagattgtt ttactacttc gtatagttct gatgatgatt ttgataaacc atctattgtc
    34501 aacagcggtt caaaagcagg atgctgttat ctttttcaag agagaattga tttcaatttt
    34561 ttcctataat gactattctg aagcgaattt agaaatcccc aaactcttgt taaacctttc
    34621 gcttttcatg gtaggatggc tctctgtcat tttacttgaa agtgatttgg cagaccatta
    34681 ccatcacttg attcgctatc aatcaagctc ctttttcgat tatacaagga aacgattggt
    34741 tgtcatttct aaatttttta ctcaagattt gtttgtctgg tttcttggtt tacttccgct
    34801 aggaattcat ttcaaaacag tcgcactttt ctttttactt gctcagttaa tgatgttgta
    34861 cttactactg tcttatctga tagcactgat tagtgcgggc gctggttttt ctttttttct
    34921 ctattttttg gcatttgtgg gacaagaatg gatgatggat catattgtaa cagtgtattt
    34981 agtactctta agcttattag ttatgttgat tcttagtcgc ttggaagaga aatttaagaa
    35041 aggataaacg atgagacttg aaattataaa tggacagaaa atttatggga aaagacctat
    35101 tttaaatcag ttgaatttgg tgtttcaatc aggaaaaatt tatggactta aaggtgataa
    35161 tggatctggc aagacggttc ttttaaagat acttgctggt tatattaagc ttgacaaagg
    35221 aaaagttctt caagatggta aagtttacgg ggtaaaaaat cattatattc aggatgcagg
    35281 aattttaatt gaaaaagtcg agtttttatc tcatttatcc ctgagagaaa atttggaact
    35341 gttaaggtat ttttcatcta aagttacgga aaaaagaatt gcctattgga ttcaatacta
    35401 tgatttacag gaatttgaag atgttgaata ccgtcattta tccttgggaa caaagcaaaa
    35461 aatggccttg attcaagcct ttatttcctc tccttctata ctctttctcg atgaacctat
    35521 gaatgctttg gatgagaaaa gtgtgaggtt aaccaaacag gtcattttat cttacctgaa
    35581 aaaagaaaat ggtctggtta tcctgacgtc gcacatatcg gaagatattt cagacctttg
    35641 tacagatgta ttagttgtcg aaaatggaca tatacaatat gtaaaggata tacaatccta
    35701 ggagatggct tatggcacat ctaaaatcat ttattacacg ctattccaag gtttatattg
    35761 gtttagttct gctgatctgg ctgtctttct tctttatccc ttgggataga gcgattctgg
    35821 gggtaaggat tgacatcttc atcatacaga aagtcttgct agtttttgga attctgtcca
    35881 ttttgatggc cttgctgtcc aagaaagtca gtctctttgt ttttggactg atttgctgtc
    35941 tttctctttg gattaactta tttatcacat ttgccatttt gccgattttt ggcaattaaa
    36001 cagtcataaa agtcggagag gttagcttga aaactaacct ctttttcctt ttcaaaatgg
    36061 ggattcttcc ttgaaaataa tcagtaattg tgctaaaatt aaaggaacat tctaaaatat
    36121 tcggaattta aagtaaggaa aaacatggct aatattttaa aaacaattat cgaaaatgat
    36181 aaaggagaaa tccgtcgtct ggaaaagatg gctgacaagg ttttcaaata tgaagaccaa
    36241 atggctgctt tgactgatga ccaattaaaa gcgaaaacag ttgaatttaa agaacgttat
    36301 caaaatggag aatcactgga ttcattgctt tatgaagcat ttgcggttgt ccgtgagggt
    36361 gccaaacgtg tcctaggtct cttcccttat aaggttcagg tcatgggggg gattgttctt
    36421 caccatggtg acgtgccaga gatgcgtaca ggggaaggga aaaccttgac tgcgaccatg
    36481 ccggtatacc tcaatgccct ttcaggtaaa ggggttcacg tagttacggt taatgaatac
    36541 ttgtcagaac gtgacgcgac tgagatgggt gaattgtact cttggcttgg tttgtcagta
    36601 gggattaact tggctaccaa atctccaatg gagaaaaaag aagcctatga gtgtgatatt
    36661 acttactcaa ctaactcaga aatcggattt gactaccttc gtgacaatat ggttgttcgc
    36721 gctgaaaaca tggtacaacg tccgcttaac tatgccttgg tcgatgaggt tgactctatc
    36781 ttgattgacg aggctcgtac acctttgatt gtatcaggtg ccaatgcggt tgaaaccagt
    36841 cagttgtatc acatggcaga ccactatgta aaatctttga acaaagatga ctacatcatc
    36901 gatgtgcagt ctaagactat tggtttgtct gattcaggga ttgacagggc tgaaagctac
    36961 ttcaaacttg aaaacctcta tgacatcgaa aacgtggctt tgacccactt tatcgataac
    37021 gcccttcgtg ccaactacat catgcttctc gatattgact atgtggtgag cgaagagcaa
    37081 gaaatcttga ttgtcgacca atttacaggt cgtaccatgg aaggtcgtcg ttattctgat
    37141 ggattgcacc aagctattga agccaaagaa ggtgtgccaa tccaggatga aaccaagaca
    37201 tctgcctcaa tcacgtacca aaaccttttc cgtatgtaca aaaaattgtc tggtatgacg
    37261 ggtacaggta agactgagga agaagaattt cgtgaaatct acaacattcg tgttattcca
    37321 atcccaacaa accgtcctgt tcaacgtatt gaccactcag accttcttta tgcaagtatc
    37381 gaatctaagt ttaaagcggt tgtcgaagac gttaaggctc gttaccaaaa gggtcaacct
    37441 gtcttggttg gtacagtagc ggttgaaact agtgactaca tttctaagaa attggttgca
    37501 gctggtgttc ctcacgaagt cttgaatgcc aaaaaccact atagagaagc ccaaatcatc
    37561 atgaatgctg gtcaacgtgg tgccgttacc atcgcaacca acatggcggg tcgtggtacc
    37621 gacatcaagc ttggtgaagg tgttcgtgaa cttggaggac tttgtgttat tggtacagaa
    37681 cgtcatgaaa gtcgtcgtat cgataaccag cttcgtggac gttcaggtcg tcaaggagat
    37741 ccaggtgagt cacaattcta cctatctctt gaagatgatt tgatgaaacg ttttggttct
    37801 gaacgcttga agggaatctt tgaacgtctc aacatgtctg aagaggcgat tgagtctcgc
    37861 atgttgacgc gtcaggttga agcagcgcaa aaacgtgtcg aaggaaataa ctacgatacc
    37921 cgtaaacaag tccttcaata cgacgatgtc atgcgtgaac aacgtgagat tatctatact
    37981 caacgttatg atgtcattac tgcagaccgt gacttggcac ctgaaattca ggcaatgatc
    38041 aaacgcacga ttggtcgtgt cgttgacggt catgcgcgtg ctaaacaaga tgagaaacta
    38101 gaggcaattt tgaacttcgc taagtacaac ttgcttcctg aagattctat tacgatggaa
    38161 gacttgtcag gcttgtctga taaggccatc aaggaagagc ttttccaacg tgccttgaag
    38221 gtttacgata gtcaggtttc aaaactacgc gatgaagaag cagttaaaga attccaaaaa
    38281 gttttgattc tacgagtggt ggataacaag tggacagatc atatcgatgc ccttgatcaa
    38341 ttgcgtaacg cggttggact tcgtggctat gctcagaaca accctgttgt tgagtatcag
    38401 gcagaaggtt tccgtatgtt taatgatatg attggttcga ttgagtttga tgtgacacgc
    38461 ttgatgatga aagcacaaat tcatgaacaa gaaagaccac aggcagaacg tcatatcagt
    38521 acaacagcga ctcgcaatat cgctgctcac caagcaagta tgccagaaga tttggatttg
    38581 agccagattg gacgcaatga actttgccca tgtggttctg gtaagaaatt taaaaactgt
    38641 cacggtaaaa gacaataaaa tgagatagtt tagaggcgga tatcttgtga aaagtaaatt
    38701 tttactgggt atccgtttgc tttataagga gatgagttat ggtatttaca gcaaaaagct
    38761 ctaaaataaa tatagaagaa gttcgtgcct tgtcaaaatt agaaggtcag gctttggaga
    38821 ggaaatcaca gcgagatcaa gagctagaag ccattatacg tggagaagac cagcgaattc
    38881 tcttggtaat cgggccatgc tcatctgaca acgaagaagc tgtccttgaa tacgctaagc
    38941 gtttggcagt cctacaagaa gaagtggcag atcgtatctt tatggttatg cgtgtttata
    39001 ctgccaaacc ccgtaccaac ggagatggct ataagggctt gattcaccag cctaacgcga
    39061 cagaagcgcc tagtcttatc aatggaatca aagccgttcg ccatcttcac tatcgtgtca
    39121 tcacagaaac agggatgaca actgctgatg aaatgcttta tcctgaaaac cttccgcttg
    39181 tagatgattt gatttcttac atggcagttg gtgcccgttc agttgaagac cagcaacacc
    39241 gctttgtggc aagtggggca ggattttcta ctggttttaa aaatccaacc tctggaaatc
    39301 tcaatgtcat gtttaatggg atttatgctg ctcaaaacaa acaaagtttc cttttcttag
    39361 gaaaagaagt agaaacaact gggaacccgc tttcacacgc tattcttcgt ggtgctctta
    39421 atgagtatgg aaaaaatatt cccaactact attatgacaa tttaattgat accattgccc
    39481 agtatgagaa aatgggtttg gaaaatcctt ttatcatcat tgataccaat catgacaatt
    39541 ctggtaagca gtatattgaa cagatccgaa ttgtccgcca gaccttgatt aaccgtgctt
    39601 ggaatgaaaa aattaagcag ttcgttcgtg gttttatgat tgagtcttat ctggaagatg
    39661 gtcgacaaaa tgagccagaa gtatttggta agtctatcac agacccttgc ctgggttggg
    39721 ataacacaga agctcttgtc agagaaattt acaaaacgtt aggagaataa gatggcattt
    39781 attgaaaaag gtcaagaaat cgatatggaa gtcatcaagg ctgaaaccca attgtctgcg
    39841 gaagccttga gactcaagga aagccgtgac agggaattgg cagatattat ttcaggggaa
    39901 gatgaccgta ttctcttggt gattggtcct tgctcttctg ataatgaaga ggcggtcttg
    39961 gaatatgctc gccgtttatc cgccttgcaa aagaaggtag cggataagat tttcatggtc
    40021 atgcgcgtgt atactgctaa gcctcgtacc aatggagacg gctataaagg attagttcac
    40081 cagccagata cttctaaggc tccaagcctg attaacggct tgcaggctgt gcgccagttg
    40141 cactaccgcg tgattacaga gactggtttg acaacggcag atgagatgct ttatccgtca
    40201 aatctgatct tggtggatga cttggtcagc taccatgccg ttggagctcg ttctgtggaa
    40261 gaccaagagc accgctttgt ggcttctggg attgatgcac cagtagggat gaaaaatcca
    40321 acctcaggaa atttgggtgt tatgtttaac gccatctatg ctgctcaaaa caagcaaacc
    40381 ttcctttatc atgggcagga agttgagaca tcaggtaatc ctttggccca tgttatcctc
    40441 cgtggagcag tcaacgagta tggcaattat atgccgaatt actactatga aaacctactc
    40501 caagccattg aacgctatga aaccatggga cttgaaaatc cttttatcct cattgacacc
    40561 aaccatgata actcaggcaa gcaatatatg gagcagattc gaattgttcg ccagaccttg
    40621 cagaatcgtg attggaatga gaaaattaaa aagacggttc gaggatttat gattgaatct
    40681 tacctagcag atggtcgtca aaaccaacca gaggtctttg gttgctctat tactgaccct
    40741 tgcctaggtt gggaaaatac agaggccttg gtagaagaga tttatgttac cttgacaaaa
    40801 taagtgaaaa ggatggagtt ggggaatctc aactcctttt gatgagaatg atagttggac
    40861 acggaattga catcgaagaa ttggcttcga tagaaagcgc agttacacga catgaaggat
    40921 ttgctaagcg tgtactgacc gctcaggaaa tggagcgctt caccagtctc aaaggacgca
    40981 ggcaaataga atatttagct ggtcgctggt cggctaagga ggccttttcc aaggctatgg
    41041 gaacgggcat tagcaagctc ggttttcagg atttggaagt cttgaacaat gaacgtgggg
    41101 cgccttattt tagtcaggca ccattttcag gaaagatttg gctgtctatc agccacaccg
    41161 atcagtttgt gacagccagt gtcattttgg aggaaaatca tgaaagctag tccacataga
    41221 ccaaccaagg ctctgattca tctgggagct attcgacaaa atattcagca aatgggggct
    41281 catatccctc aaggaacgct caagttggct gtggtcaagg ccaatgctta tggtcatgga
    41341 gctgttgccg ttgccaaggc aattcaagat gatgttgatg gcttttgcgt ttccaatatc
    41401 gatgaagcca ttgaactcag acaagctgga ctcagcaagc caatcctcat tttaggagtt
    41461 tctgaaatcg aagctgttgc tctagctaaa gaatatgact tcaccttgac agtggctgga
    41521 ctggagtgga ttcaagcact cttagataag gaagtggacc taactggatt gacagtccac
    41581 ctcaagattg attcagggat gggacggatt ggttttagag aggcaagtga ggttgagcag
    41641 gctcaagatt tgctccaaca acacggtgtt tgtgttgaag gaatctttac ccactttgct
    41701 actgctgatg aggaatcaga tgactatttt aatgcccagt tagaacggtt taaaactatt
    41761 ttagctagta tgaaggaagt tccagagctg gttcatgcta gcaattctgc aacgactctt
    41821 tggcatgtag agactatttt caatgcggtt cgtatgggag atgccatgta tggcctcaat
    41881 ccaagtggag cggtcttgga tttgccttat gatttgatac cggccttgac cttggagtct
    41941 gctctggttc atgtcaagac agttccagct ggagcttgca tgggctatgg agcaacttat
    42001 caagcggata gcgagcaagt catcgcgacc gtgccaatcg ggtatgcaga tggatggaca
    42061 agagacatgc aaaatttctc tgtcttggta gatggccaag cttgcccaat tgtcggcagg
    42121 gtttcgatgg accaaatcac tattcgattg cctaagcctt acccactcgg aaccaaggta
    42181 accttgattg gctccaatgg ggataaggaa atcactgcaa ctcaggtagc gacctaccgc
    42241 gtaaccatta actatgaggt ggtttgcctc ctcagcgacc gtattccgag agaatattat
    42301 tagaaaagaa aggagtggag catgaatcta catcaaccct tgcatgtctt gcctggtgtg
    42361 ggaccaaagt cagcagaaaa atacgccaaa ctaggaattg aaaacttgca agatctcttg
    42421 ctctactttc ctttccgtta tgaagacttc aaaaccaagc aggtgctgga gctggaagac
    42481 ggtgagaagg cagttctttc tggtcaggta gtgactcctg ctagtgtcca gtattatggt
    42541 ttcaagcgca atcgcctgcg ttttagtctc aagcagggag aggtcgtttt tgcggtgaat
    42601 ttctttaacc agccctatct ggctgataaa atagagttgg gagcaaccct tgctgtcttt
    42661 ggaaaatggg accgcgctaa ggctagtctg actgggatga aggttctggc tcaggtagaa
    42721 gatgacctcc agcctgtcta tcgtctggct cagggaatca gtcaggccag tctggtcaag
    42781 gtcatcaaga cggcttttga tcagggactg gacctcttga tagaagaaaa tctgccccag
    42841 tctttactag acaaatacaa actcatgtcc cgttgtcagg cagtccgagc tatgcatttt
    42901 ccaaaggatt tggcagaata caagcaggct cttcgccgta tcaagtttga ggaactcttt
    42961 tatttccaaa tgcagctgca gatgctcaag tctgaaaata gagttcaggg aagtggtctg
    43021 gttctgaatt ggtctcagga aaaagtgaca gcagttaaag caagtcttcc ttttgccctg
    43081 acccaagctc aggaaaagag tttgcaggaa attttaactg atatgaagtc cgaccactac
    43141 atgaatcgtc tcctacaagg agatgtgggg agcggaaaaa cggtagtcgc tggcttggcc
    43201 atgtttgcgg cagtgacagc aggttatcag gctgccctaa tggtaccaac agaaatcctc
    43261 gcagagcaac actttgagag tttacagaac ctttttccca atttgaaact ggctctcttg
    43321 acaggttcct tgaaagctgc agaaaagaga gaggtcttgg agaccattgc caagggtgag
    43381 gctgatttga ttatcggaac tcacgctctg atacaagatg gggtggagta tgctcgtctt
    43441 ggtttgatta ttatcgatga gcagcaccgt tttggtgtag ggcaaaggcg tattttacgg
    43501 gaaaaaggtg acaatccaga tgtcctcatg atgacggcga ctcccattcc acggacgctt
    43561 gccatcacag cctttggaga tatggatgtt tccattatcg accagatgcc agcaggtcgg
    43621 aagcctattg tgacgcgctg gatcaaacat gagcaactac ctcaggtctt gacttggtta
    43681 gagggggaaa ttcaaaaagg ttcccaagcc tatgtcatct ctcctttgat tgaagaatca
    43741 gaagctctag atttgaaaaa tgccattgcc ttatcagagg agttgacgac tcattttgca
    43801 ggcaaggcag aggtggctct tctacatggt aggatgaaga gtgacgaaaa agaccagatc
    43861 atgcaggatt tcaaggagag aaagacggat attctggttt cgacgacggt tattgaggtt
    43921 ggggtcaacg ttcccaatgc gactgtcatg attatcatgg atgccgatcg cttcgggctc
    43981 agccagcttc accagcttag aggtcgtgtc ggtcgggggg acaagcagtc ctacgctgtt
    44041 ctcgttgcca atcccaagac ggattctggg aaagaccgca tgcgcatcat gacagaaacg
    44101 accaatggat ttgtccttgc ggaggaagat ttgaaaatgc gtggttctgg tgagattttt
    44161 ggaaccagac agtcaggact tccagagttc caagtggctg atattatcga agattttccg
    44221 attttagaag aagcaagaaa ggttgctagc tacattagtt ctatagaagc ttggcaagaa
    44281 gatccagagt ggcgcatgat tgcccttcat ctggaaaaga aagaacatct ggattaagct
    44341 ttctctaagg aaaacttaag ctagttttta gatttggctc ttatactaaa gtcatcaaaa
    44401 agaaacgagg actctcatat gacagtaacg attaaagtaa attaccaaac cactttccaa
    44461 aagaaggaag caaaaaacta gtataaacag aagagagagc gaaatgctct tttttcgttt
    44521 ctaaaactac tttcagccca tcatcctaaa agtaaagaat ctaaattcac tttctattta
    44581 tccttctttc ttgcattgat tacatagata tgctacagtt gtggtaacga ttacaaaata
    44641 aaaggagcat gctatgaaaa atccagcttt gctagaagaa attaagacct atagaggaag
    44701 ggatgaggtt ccggaagact ttgatgcttt ctgggatggg gaagtgaaaa atgtttccac
    44761 gcttccatcc taccacttgg aggaaagaga tttccacatt cctcaagtca agtgctatga
    44821 gttaacattt gaaggaagca aggaaggaaa ggtctatgca cgcattgttc ttccaaagag
    44881 tgaggagaag gttccactaa tcttccattt tcatggttat atgggacgtg gctgggactg
    44941 ggccgacatg ctgggcttca ccgtagctgg ttacggtgtt gtttccatgg atgtgcgggg
    45001 ccagtcaggt tactcacaag acggcttgcg ttctccttta ggaaataccg tgaaggggca
    45061 tattatccgt ggtgctatgg aaggtcggga ccacctcttt tataaggatg tttatctgga
    45121 tatttaccag ttggtcgaaa ttgttgctag tctgtctcag gttgatgaga agcgtctttc
    45181 tagctatggt gcctcacaag gaggggctct agctctagtt gcagcagcgc tcaatcctcg
    45241 aattcagaaa acagttgcca tttatccctt cttgtcagac ttcagacggg tgattgagat
    45301 tggtaatact agcgaggctt acgacgaact tttccgttat ttcaagtttc acgacccctt
    45361 ccatgaaaca gaggaggaaa tcatggcgac ccttgcctat atcgatgtca aaaatcttgc
    45421 ccatcgtatc caaggtgagg ttaagatgat tacgggcttg gacgacgatg tttgctatcc
    45481 cattacccag tttgcgattt ataatcgtct gacctgcgat aaaacctatc gcatcatgcc
    45541 tgagtatgct cacgaagcca tgaatgtatt tgtcaatgac caagtctaca actggctctg
    45601 tggaagtgag attcctttta aatatttaaa ataaggagtc gactctaagc acaaaatctt
    45661 aaaaattaca aacacgcata gtatcagggg cttaagaaaa cttgatacta tgcgttttat
    45721 catggaaata tagtaaaatg aaacaagaac aggacaaatt gatcaggaca gtcaaatcga
    45781 tttctaacaa tgttttagaa gcaaatgtgt actattctag tttcaatcta ttatatttat
    45841 agaatttttt gttgctagat ttgtcaaatt gcttaaaata atttttttca gaaagcaaaa
    45901 gccgatacct atcgagtagg gtagttcttg ctatcgtcag gcttgtctgt aggtgttaat
    45961 acttttcaaa aatctcttta aaccacgtca gcttcgtctt gccgtaggta tggttactga
    46021 cttcgtcagt tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttctat
    46081 ccacaacctc aaaacagtgt tttgagctga cttcgtcagt tctatccaca acctcaaaac
    46141 agtgttttga gctgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga
    46201 cttcgtcagt tctatccaca acctcaaaac ggtgttttga gctgacttcg tcagttctat
    46261 ctgccacctc aaaacggtgt tttgagctga cttcgtcagt tctatctgcc acctcaaaac
    46321 ggtgttttga gctgacttcg tcagttctat ctgccacctc aaaacggtgt tttgagctga
    46381 cttcgtcagt tctatctgcc acctcaaaac agtgttttga gctgacttcg tcagtcttat
    46441 ctaccacctc aaaacagtgt tttgagcatc atgcggctag cttcttagtt tgctctttga
    46501 ttttcattga gtataaaaac agatgagttt ctgttttctt tttatggact ataaatgttc
    46561 agctgaaact actttcaagg acattattat ataaaagaat tttttgaaac taaaatctac
    46621 tatattacac tatattgaaa gcgttttaaa aatgaggtat aataaattta ctaacactta
    46681 taaaaagtga tagaatctat ctttatgtat atttaaagat agattgctgt aaaaatagta
    46741 gtagctatgc gaaataacag atagagagaa gggattgaag cttagaaaag gggaataata
    46801 tgatatttaa ggcattcaag acaaaaaagc agagaaaaag acaagttgaa ctacttttga
    46861 cagttttttt cgacagtttt ctgattgatt tatttcttca cttatttggg attgttccct
    46921 ttaagctgga taagattctg attgtgagct tgattatatt tcccattatt tctacaagta
    46981 tttatgctta tgaaaagcta tttgaaaaag tgttcgataa ggattgagca ggaagtatgg
    47041 tgtaaatagc ataggctgat gtccatcatt tgcttataaa gagatatttt agtttaattg
    47101 cagcggtgtc ctggtagata aactagattg gcaggagtct gattggagaa aggagagggg
    47161 aaatttggca ccaatttgag atagtttgtt tagttcattt ttgtcattta aatgaactgt
    47221 agtaaaagaa agttaataaa agacaaacta agtgcatttt ctggagtaaa tgtcttattt
    47281 cagaaatcgg gatatagata tagagaggat cagtatgaat cggagtgttc aagaacgtaa
    47341 gtgtcgttat agcattagga aactatcggt aggagcggtt tctatgattg taggagcagt
    47401 ggtatttgga acgtctcctg ttttagctca agaaggggca agtgagcaac ctctggcaaa
    47461 tgaaactcaa ctttcggggg agagctcaac cctaactgat acagaaaaga gccagccttc
    47521 ttcagagact gaactttctg gcaataagca agaacaagaa aggaaagata agcaagaaga
    47581 aaaaattcca agagattact atgcacgaga tttggaaaat gtcgaaacag tgatagaaaa
    47641 agaagatgtt gaaaccaatg cttcaaatgg tcagagagtt gatttatcaa gtgaactaga
    47701 taaactaaag aaacttgaaa acgcaacagt tcacatggag tttaagccag atgccaaggc
    47761 tccagcattc tataatctct tttctgtgtc aagtgctact aaaaaagatg agtacttcac
    47821 tatggcagtt tacaataata ctgctactct agaggggcgt ggttcggatg ggaaacagtt
    47881 ttacaataat tacaacgatg cacccttaaa agttaaacca ggtcagtgga attctgtgac
    47941 tttcacagtt gaaaaaccga cagcagaatt gccaaatggt cgagttcgcc tctacgtaaa
    48001 cggggtatta tctcgaacaa gtctgaaatc tggcaatttc attaaagata tgccagatgt
    48061 aacgcatgtg caaatcggag caaccaagcg tgccaacaat acggtttggg ggtcaaatct
    48121 acagattcgg aatctcactg tgtataatcg tgctttaaca ccagaagagg tacaaaaacg
    48181 tagtcaactt tttaaacgct cagatttaga aaaaaaacta cctgaaggag cggttttaac
    48241 agagaaaacg gacatattcg aaagcgggcg taacggtaaa ccaaataaag atggaatcaa
    48301 gagttatcgt attccagcac ttctcaagac agataaagga actttgatcg caggtgcaga
    48361 tgaacgccgt ctccattcga gtgactgggg tgatatcggt atggtcatca gacgtagtga
    48421 agataatggt aaaacttggg gtgaccgagt aaccattacc aacttacgtg acaatccaaa
    48481 agcttctgac ccatcgatcg gttcaccagt gaatatcgat atggtgttgg ttcaagatcc
    48541 tgaaaccaaa cgaatctttt ctatctatga catgttccca gaagggaagg gaatctttgg
    48601 aatgtcttca caaaaagaag aagcctacaa aaaaatcgat ggaaaaacct atcaaatcct
    48661 ctatcgtgaa ggagaaaagg gagcttatac cattcgagaa aatggtactg tctatacacc
    48721 agatggtaag gcgacagact atcgcgttgt tgtagatcct gttaaaccag cctatagcga
    48781 caagggtgat ctatacaagg gtgaccaatt actaggaaat atctacttca caacaaacaa
    48841 aacttctcca tttagaattg ccaaggatag ctatctatgg atgtcctaca gtgatgacga
    48901 cgggaagaca tggtcagcgc ctcaagatat tactccgatg gtcaaagccg attggatgaa
    48961 attcttgggt gtaggtcctg gaacaggaat tgtacttcgg aatgggcctc acaagggacg
    49021 gattttgata ccggtttata cgactaataa tgtatctcac ttaaatggct cgcaatcttc
    49081 tcgtgtcatc tattcagatg atcatggaaa aacttggcat gctggagaag cggtcaacga
    49141 taaccgtcag gtagacggtc aaaagatcca ctcttctacg atgaacaatg aacgtgcgca
    49201 aaatacagaa tcaacggtgg tacaactaaa caatggagat gttaaactct ttatgcgtgg
    49261 tttgactgga gatcttcagg ttgctacaag taaagacgga ggagtgactt gggagaagga
    49321 tatcaaacgt tatccacagg ttaaagatgt ctatgttcaa atgtctgcta tccatacgat
    49381 gcacgaagga aaagaataca tcatcctcag taatgcaggt ggaccgaaac gtgaaaatgg
    49441 gatggtccac ttggcacgtg tcgaagaaaa tggtgagttg acttggctca aacacaatcc
    49501 aattcaaaaa ggagagtttg cctataattc gctccaagaa ttaggaaatg gggagtatgg
    49561 catcttgtat gaacatactg aaaaaggaca aaatgcctat accctatcat ttagaaaatt
    49621 taattgggaa tttttgagca aagatctgat ttctcctacc gaagcgaaag tgaagcgaac
    49681 tagagagatg ggcaaaggag agatgggcaa aggagttatt ggcttggagt tcgactcaga
    49741 agtattggtc aacaaggctc caacccttca attggcaaat ggtaaaacag cgactttcct
    49801 aacccagtat gatagcaaga ccttgttgtt tgcagtagat aaggaagata tcggacagga
    49861 aattattggt atagctaaag gaagcatcga aagtatgcat aatcttcctg taaatctagc
    49921 aggtgccaga gttcctggcg gagtaaatgg tagcaaagca gcggtgcatg aagttccaga
    49981 atttacaggg ggagttaatg gtacagagcc agctgttcat gaaatcgcag agtataaggg
    50041 atctgattcg cttgtaactc ttactacaaa agaagattat acttacaaag ctcctcttgc
    50101 tcagcaggca cttcctgaaa caggaaacaa ggagagtgac ctcctagctt cactaggact
    50161 aacagctttc ttccttggtc tgtttacgct agggaaaaag agagaacaat aagagaagaa
    50221 ttctaaacat ttgattttgt aaaaatagaa ggagatagca ggttttcaag cctgctatct
    50281 ttttttgatg acattcaagc tgatacgaaa tcataagagg tctgaaacta ctttcagagt
    50341 agtctgttct ataaaatata gtagattgaa ataagatgtg aacaactcta tcaggaaagt
    50401 caaattaatt tatagaaaaa ttttagcagt caaggtgtac tgttatagat tcaatatatt
    50461 atgcgactat taaccttgtc ttctcctaaa attgactttc ttgttttctt atcttgtcca
    50521 ctcgaaacaa gtattgtaag aatttgatta tttttgaaag tacttttaat atacttgata
    50581 tagttaaaaa agatttgaaa ctaaattcca aattagaaaa agacttgaaa tactaaaaaa
    50641 aaaaagtata ctctaattga aaacggtaac aaaactaatt tagagaatga aatatagagt
    50701 atttctctct taaaagtttt tggtgaaacg agatgtagaa aggagattta gccaaagagt
    50761 ctattagtgc tagaataata gattagaatt attttagaaa aacgaagtga gcagcttata
    50821 aattcaagtc cccaaataga ttcatactag tatcttttgc aaaaaataaa gggcgacttc
    50881 cttcatgaat atcaatttca tctataagga aggtagctaa ttgaactaac ttatttattc
    50941 tgtttgtcgc tagaaaaatc agacctcctt gtgaagattg aggagatact gaatgaaaat
    51001 caaagaagaa actagcaagc tagtagcaga ttgcccaaaa caccgctttg aggttgtaga
    51061 taagactgac ctatataatc caaggtgaag cgactgtggt ttgaagagat tttcaaagag
    51121 tataggctag agagtagtgt ttttatgtcc ttctagtaga aaatgctaga cagaagaatg
    51181 gggaacttgg ataggaaaaa tagattgaga aaggaggtta gaagagatga ttattacaaa
    51241 aattagccgt ttaggaactt atgtgggagt caatccacat tttgcaacat taatagattt
    51301 tctagaaaaa acaggactag aaaatttaac agaaggttcg attgctatcg atggtaatcg
    51361 attgtttggg aattgcttta tttatctagc agatggtcaa gcaggggctt tctttgaaac
    51421 acaccaaaaa tatttggata ttcatttagt tttggaaaac gaagaagcca tggctgttac
    51481 atcgccggaa aatgtaagcg ttacccaaga atatgatgaa gagaaagata ttgaattata
    51541 cacagggaaa gtggaacagt tggttcattt gagagctggt gaatgcctca tcacttttcc
    51601 agaagattta catcaaccca aggttcgtat aaatgatgaa cctgtgaaaa aagttgtctt
    51661 taaagttgcg atttcttaat gtagaaagag aagaacgatg aaaaaaatga gaaagttttt
    51721 atgtctagct ggaattgcgc tagcggctgt tgccttggta gcttgttcag gaaaaaaaga
    51781 agctacaact agtactgaac caccaacaga attatctggt gagattacaa tgtggcactc
    51841 ctttactcaa ggaccccgtt tagaaagtat tcaaaaatca gcagatgctt tcatgcaaaa
    51901 gcatccaaaa acgaaaatca agattgaaac attttcttgg aatgacttct atactaaatg
    51961 gactacaggt ttagcaaatg gaaatgtgcc agatatcagt acagctcttc ctaaccaagt
    52021 aatggaaatg gtcaactcag atgctttggt tccgctaaat gattctatca agcgtattgg
    52081 acaagataaa tttaacgaaa ctgccttaaa tgaagcaaaa atcggagatg attactactc
    52141 tgttcctctt tattcacatg cacaagtcat gtgggttaga acagatttgt taaaagaaca
    52201 taatattgag gttcctaaaa cttgggatca actctatgaa gcttctaaaa aattgaaaga
    52261 agctggagtt tatggcttgt ctgttccgtt tggaacaaat gacttaatgg caacacgttt
    52321 cttgaacttc tacgtacgta gtggtggagg aagcctctta acaaaagatc ttaaagcaga
    52381 cttgacaagc caacttgctc aagatggtat taaatactgg gttaaattgt ataaagaaat
    52441 ctcacctcaa gattctttga attttaatgt ccttcaacaa gctaccttgt tctatcaagg
    52501 aaaaacagca tttgacttta actctggctt ccatatcgga ggaattaatg ccaacagtcc
    52561 tcaattgatt gattcgattg atgcttatcc tattccaaaa atcaaagagt ctgataaaga
    52621 ccaaggaatt gaaacctcaa acattccaat ggttgtttgg aaaaattcaa aacatccaga
    52681 agttgctaaa gcattcttag aagcacttta taatgaagaa gactacgtta aattccttga
    52741 ttcaactcca gtaggtatgt tgccaactat taaggggatt agcgattctg cagcctataa
    52801 agaaaatgaa actcgtaaga agtttaaaca tgctgaagaa gtaattactg aagctgttaa
    52861 aaaaggtact gctattggtt atgaaaatgg accaagtgta caagctggta tgttgactaa
    52921 ccaacacatt attgaacaaa tgttccaaga tatcattaca aatggaacag atcctatgaa
    52981 agcagcaaaa gaagcagaaa aacaattaaa cgatttattt gaggctgttc agtagatgta
    53041 aaagactaga aaataggtgg gctagtgatc tgaaaagctc tagcccaatt ttgtaaaaga
    53101 agggagaagg agaatggtta aagaacgtaa tttaactcgc tggatatttg ttttgccagc
    53161 tatgattatc gtaggattac tctttgttta tccgtttttc tcgagtattt tttatagctt
    53221 taccaataag catttgatta tgcctaatta taaatttgtt ggtttggcta actataaagc
    53281 tgtgctatca gatcccaact tctttaatgc gttctttaat tcaattaagt ggaccgtttt
    53341 ctcattagtt ggtcaagttt tagtagggtt tgtgttggct ttagctcttc acagagtacg
    53401 ccacttcaag aaattatata ggaccttatt gattgttcct tgggcatttc ctaccatcgt
    53461 tattgccttc tcttggcagt ggattctaaa cggggtttat ggctacttac ctaatctaat
    53521 cgtaaaatta ggtttaatgg aacatacacc tgcatttttg acagatagta catgggcatt
    53581 cctatgtttg gtgtttatca acatttggtt tggagcacca atgattatgg ttaatgtgct
    53641 ttcagctttg caaacagtac cagaagaaca atttgaggct gctaagatag atggtgcttc
    53701 aagttggcag gtgttcaagt ttatcgtctt tccacatatt aaagtggttg taggacttct
    53761 agttgttttg agaactgtat ggatctttaa taactttgac attatctacc tcattactgg
    53821 tggtggacca gccaatgcta caacgacgct tccaattttt gcttacaacc tgggttgggg
    53881 aactaaattg ttgggtcgtg cttcagcagt tacagtattg ctctttatct tcttggtggc
    53941 gatttgcttt atctactttg ctatcatcag taagtgggaa aaggagggta gaaaataatg
    54001 aagaagaaat ccggtattta tttagatatt ctctcacatg tacttttagt tggtgcgacc
    54061 atcgttgcag ttttcccatt ggtatggatt atcatatctt ctgtcaaagg gaaaggggaa
    54121 ttaactcagt atccaacacg attttggcct gaacagttta cattagatta tttcactcat
    54181 gttatcaacg atttgcactt cattgataac attcgaaaca gtttaatcat tgccttggct
    54241 acaaccctta ttgcgattat tatttctgct atggcagcct atggtattgt tcgattcttt
    54301 cctaaattgg gagcaatcat gtcgagacta ctcgtcatta cctatatttt cccaccaatt
    54361 ttgttagcaa ttccctattc aattgccatt gctaaagttg ggttaacaaa tagtttattt
    54421 ggcttgatga tggtttatct atcttttagt gttccatatg cagtttggct cttagttgga
    54481 tttttccaaa cagttccaat tggaattgaa gaagcggcta gaattgatgg tgcaaataaa
    54541 tttgttacgt tttataaagt tgtgctaccg attgtagcac caggtattgt agcaacagct
    54601 atttatacat ttatcaatgc ttggaatgaa ttcctgtatg ccttgatttt gattaacaat
    54661 acaggaaaga tgacagtagc agtagccctt cgttcactta atggttcaga aatactagac
    54721 tggggagata tgatggcagc gtctgttatt gtagttcttc catcaattat tttcttctct
    54781 atcatccaaa ataagattgc aagtggatta tcagaaggat ctgtgaagta gacgaaagaa
    54841 ggaaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt tgtaggcatt
    54901 agtcttttaa tgggagttcc cactttgatt catgcgaatg aattaaacta tggtcaactg
    54961 tccatatctc ctatttttca aggaggttca tatcaactga acaataagag tatagatatc
    55021 agctctttgt tattagataa attgtctgga gagagtcaga cagtagtaat gaaatttaaa
    55081 gcagatgaac caaactctct tcaagctttg tttggcctat ctaatagtaa agcaggcttt
    55141 aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt agaaataaga
    55201 gacgcccaaa agggaataaa ttatttattt tctagaccag cttcattatg gggaaagcat
    55261 aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga taaaacatac
    55321 acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt tttgccaatt
    55381 tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga aggtaaggaa
    55441 cattacctcg caaaaggaag tattgatgaa atcagtctat ttaacaaagc aattagtgat
    55501 caggaagttt caaatattcc cttgtcaaat ccatttcagt taattttcca atcaggagat
    55561 tctactcaag ctaactattt tagaataccg acactatata cattaagtag tggaagagtt
    55621 ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa gattaatatt
    55681 gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt tgctatgaag
    55741 tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt aaagaatagt
    55801 caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa aaaatctggg
    55861 aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa tgcaaataaa
    55921 gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa gaagaatgga
    55981 gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga aacaactaat
    56041 aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg aaagtcttta
    56101 acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaaa acataatgga
    56161 aaacaggttc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac tcctactaat
    56221 tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt taagttgttg
    56281 cctccgttct taggagaaaa acataatgga acttacttgt gtcctggaca aggtttagca
    56341 ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact aacctatctc
    56401 atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc gtttaaaaat
    56461 gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac attctttaga
    56521 accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac atggtcggaa
    56581 gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc tgcaattaaa
    56641 tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa ttctagaagt
    56701 ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga tagtattgat
    56761 tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc tgcgattaca
    56821 gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg gtcgagaaat
    56881 gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga tttaacaaaa
    56941 taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt ggagctgaat
    57001 tggctcgcta catgcaaaaa aatgatggag cagagattac tcttctctat gatccagata
    57061 atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta gatgagttgg
    57121 tttctagcga tgaagtagac tgtgttatcg tcgcaactcc aaataatctt cataaggaac
    57181 cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca attgcgcttt
    57241 cttatcaaga ttgtcgcgag atggtagatg tgtgtaaaga aaacaatgta acctttatgg
    57301 caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc attaatcaag
    57361 gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa gaacaacaac
    57421 cgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat caccacatcc
    57481 atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta accatgacag
    57541 gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg atttttgtca
    57601 atatggaatt ttctaataag cgttttgctt tgttagaatg gggttcagct tatcgttggg
    57661 gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac ttattcaact
    57721 gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac gaatcgcaag
    57781 aagaagatga tgatcggact cgtatctatc atagtacaga gatggatgga gcaattgctt
    57841 atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat aaagaaatgc
    57901 gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca aaacttttga
    57961 caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag tctatgtttg
    58021 aagatcgcaa agtaagattg tcagaaattg taaaataaat tttggtattc tcctatctat
    58081 aggtcgactt gctcctctga aagtactttt agaggagctg tttgactttg ctagtttttg
    58141 aaactgaaat ctattatact acaaactatt gaaagcgttt taattttaag gtataataat
    58201 ctcatagaaa taaagaaaag gaggaaagag gatgccacag attagcaaag aagccttgat
    58261 tgagcaaatc aaagatggaa tcatcgtttc ttgtcaggct cttcctcatg aaccgcttta
    58321 tacagaagtg ggaggggtga ttcccttgct ggtcaaagcg gctgagcaag gtggagcagt
    58381 cggtatccga gcaaacagtg ttcgcgatat caaggaaatt aaggaagtca ctaaacttcc
    58441 aatcattggg attatcaaac gtgattatcc acctcaggaa ccctttatca cggctactat
    58501 gaaagaagtt gatgaattgg cagaactgga catcgaggtg attgctctgg attgtaccaa
    58561 gcgtgaacgc tacgatggtt tggaaattca agagttcatt cgtcaggtta aggagaaata
    58621 tcctaatcag cttttgatgg ctgatactag tatcttcgaa gaagggctag cagctgtaga
    58681 agcaggaatt gactttgtcg gaacaacctt atcaggctac acatcctaca gtccaaaagt
    58741 agacggtcca gattttgaat tgattaagaa actctgtgat gccggtgtag atgtcattgc
    58801 agaaggaaaa attcatacac cagaacaagc caaacaaatc cttgaatatg gagtgcgagg
    58861 catcgttgtt ggtggcgcca ttactagacc aaaagagatt acagaacgct tcgttgctag
    58921 tcttaaataa gatgtgaggg ggagttttat gtttaaagtt ttacaaaaag ttggaaaagc
    58981 ttttatgtta cctatagcta tacttcctgc agcaggtcta cttttgggga ttggtggtgc
    59041 actttcaaac ccaaccacga tagcaactta tccaatacta gacaatagta tttttcaatc
    59101 aatattccaa gtaatgagct ctgcaggaga ggttgtattc agtaatttgt cactacttct
    59161 ctgtgtggga ttatgtattg gcttagcgaa acgagataaa ggaaccgctg cgttagcagg
    59221 agtaactggt tacttagtta tgactgcaac gatcaaagct ttagtaaaac tttttatggc
    59281 agaaggatct gcaattgata ctggagttat tggagcatta gttgtcggaa tagttgccgt
    59341 atatttgcac aaccgatata acaatattca attaccttcc gctttaggat tctttggagg
    59401 ttcacgcttc gttcctattg ttacatcgtt ctcttctatc ttgattggct ttgtcttctt
    59461 tgttatttgg ccacctttcc aacaacttct tgtttctaca ggtggatata tttctcaggc
    59521 gggtccaatt ggaacttttc tatatggatt tttaatgaga ctttctggag cagtaggctt
    59581 acatcatata atttacccta tgttttggta tactgaactt ggtggtgttg aaactgttgc
    59641 aggacaaaca gtggttggag ctcaaaaaat attttttgct caattagccg atctggccca
    59701 ttctggatta tttacagaag gaacaaggtt ttttgcaggt cgtttctcaa caatgatgtt
    59761 cggtttaccg gctgcctgtt tagcgatgta ccatagtgtt cctaaaaatc gtcgtaaaaa
    59821 atacgcgggt ttgtttttgg gagttgcttt aacatctttt attaccggta ttacagaacc
    59881 aattgaattt atgtttctat tcgtcagtcc ggttctatat gttgttcacg cattccttga
    59941 tggtgttagc ttctttattg cagacgtctt aaatatttca ataggaaaca cattttcagg
    60001 aggtgtaatc gatttcacat tatttggaat tttgcagggg aacgctaaga cgaattgggt
    60061 tcttcagatt ccatttggac ttatttggag tgttttgtat tatattattt ttagatggtt
    60121 cattactcaa ttcaacgttc taacgccagg gcgaggagaa gaagtagatt ctaaagaaat
    60181 ttctgaatcc gcagattcaa cttcaaatac tgcagattat ttaaaacagg atagcctaca
    60241 aattatcaga tccttgggtg gatcaaataa tatagaagat gtagatgctt gtgtgacacg
    60301 tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa aacaaattgg
    60361 tgcagttgat gtcttagaag tgaagggtgg cattcaagca atctatggag caaaagcaat
    60421 cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac ttactgactt
    60481 aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca tacaagaaat
    60541 aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa atgaaattta
    60601 gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct gcttgtggca
    60661 attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa acagaaatca
    60721 cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt ggaacttatg
    60781 aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg aaattggaaa
    60841 ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca ggaacagctc
    60901 cagacgtact ctttgatgca ccaggacgta tcatccaata cggtaaaaac ggtaaattgg
    60961 ctgagttgaa cgacctcttc acagatgaat ttgttaaaga tgtcaacaat gaaaacatcg
    61021 tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct gccccattct
    61081 acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt gtaaaagaag
    61141 gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag ggttacacac
    61201 caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc tttatctcta
    61261 acctttatag cggttctgta acagatgaaa aagttagcaa atatacaact gatgatccta
    61321 aattcgtcaa aggtcttgaa aaagcaacta gctggattaa agacaatttg atcaataatg
    61381 gttcacaatt tgacggtggg gctgatatcc aaaactttgc caacggtcaa acatcttaca
    61441 caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa gcaagtaagg
    61501 tagaagtggt agaagtacca ttcccatcag acgaaggtaa gccagctctt gaataccttg
    61561 taaacgggtt tgcagtattc aacaataaag acgacaagaa agtcgctgca tctaagaaat
    61621 tcatccagtt tatcgcagat gacaaggagt ggggacctaa agacgtagtt cgtacaggtg
    61681 ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg gaaacaatca
    61741 gcggctggac tcaatactac tcaccatact acaacactat tgatggattt gctgaaatga
    61801 gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa ccagcagatg
    61861 ctttgaaagc cttcactgaa aaagcgaacg aaacaatcaa aaaagctatg aaacaatagt
    61921 ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata cccccttttc
    61981 cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga aactgtcacg
    62041 aaattaaaat gaagttctta cataagcgaa tcataaaaaa tttcattttg attttaaaac
    62101 agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg tgaaagtcaa
    62161 taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag tattattctt
    62221 ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt tctttaacta
    62281 ctcaatgact aaatttgagt ttgtaggctt ggataactat atccgtatgt ttaaagatcc
    62341 tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg taccagttgt
    62401 tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca ttgccagatc
    62461 cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg tgacagttgt
    62521 ttggaaatgg atttatgacc cactatcagg gattctaaac tttgtcctta agtcaagcca
    62581 catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga tggcgattat
    62641 gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg ctgccatggg
    62701 gaatatcgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg agtttcaagt
    62761 tttttggaag attaaatggc caagccttct tccaacaact ctttatattg caatcatcac
    62821 aacaattaac tcattccagt gtttcgcctt gattcagctt ttgacatctg gtggtccaaa
    62881 ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat tgacagaata
    62941 cggctatgcc aacacaattg gtgtcttctt ggcagtcatg attgctatcg taagctttgt
    63001 tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag ctatgcaatc
    63061 tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt tgctcttgtt
    63121 gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca aatcacaacc
    63181 tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg aaaacttcca
    63241 acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat ttatctcatt
    63301 ggtaaccatg ttcttagttt gtgcaacctc atctctagca ggttatgtat tggctaaaaa
    63361 acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg cgcttccaaa
    63421 acaagttgtc cttgtaccat tggtacgtat cgtcaacttc atgggaatcc acgatactct
    63481 ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca tgaaacaatt
    63541 tagtgaaaat attcctacag agttgcttga atcagctaaa atcgacggtt gtggtgagat
    63601 tcgtaccttc tggagtgtag ccttcccgat tgtgaaacca gggtttgcag cccttgcaat
    63661 ctttaccttc atcaatactt ggaatgacta cttcatgcaa ttggtaatgt tgacttcacg
    63721 taacaatttg accatctcac ttggggttgc gaccatgcag gctgaaatgg caaccaacta
    63781 tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag tcttccttgt
    63841 cttccaaaaa tcctttacac agggtattac tatgggagcg gtcaaaggat aatactctgc
    63901 gaaaatcgaa tgcaaactac gtcagcttca ccttgccata cttaagtatt gcttgcggtt
    63961 agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct atcaagatac
    64021 agaagtatat tttatagatt tagagaatat ataagttata agtgtctaca aaatggaggg
    64081 tatgcagtta ctttatgaag ttttgtcaga cacttataaa cttaagaatg gttttagtta
    64141 actatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat caccttttac
    64201 aaagggattc atcccaattt agacaaggct atcgactacc tctaccaaca tcgtaaagat
    64261 tcattcgaat taggaaagta tgagattgat ggagataaag tctttctagt tgttcaggaa
    64321 aatgtcctca atcaagttga gaataatcaa tttgaacacc ataagaacta tgcagatttg
    64381 catttgctga tagaagggca tgaatattcg agctacggtt cacgtatcaa agacgaggca
    64441 gtagcattcg acgaagcgag tgacattggc tttgttcatt gtcatgaaca ctacccgctc
    64501 ttgttgggtt atcacaattt tgcgattttc ttcccaggtg agccacatca gccaaatggt
    64561 tatgcaggca tggaagaaaa ggttcgaaaa tatctcttta aaatcttgat tgattaaaaa
    64621 taggatgaat tgtttttttg taaagctttg ataatactct accatgaaat tgatctttgt
    64681 gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagta tgctgcaaga
    64741 gctagtttct tagatggaca ggggattaca gttgatgaga tgtcctggat aattaggggc
    64801 attgtgaatg gattgattgg tagatacata aaattaggta cttatgcagc taagtatggt
    64861 attagtatgg cgcgctcgat cttaagtagg gcagctgcaa ctgcggcagc aagagtaaga
    64921 ttattgacta agatttttgg atggatttta cgaatagctg tgctcgcagc tgatgtatat
    64981 ggtaattttg ccaacaatat tgctgcagct tgggatgcac atgataaaat ccctaacaat
    65041 ggtcgtataa acttttaaaa tgcgagaatg aaagcacttt gtattttttt attgtatatg
    65101 ttagcttgga cagtgcttgc aatgataatc cgtggagggc tagatggatt tgatgaacac
    65161 acttggcgta atattttagc tagtgcgttg tcctcgctat acatacatta tatatccata
    65221 gataaaaata gaaaaaagtc caaaagaaaa aagaaaaaat agatttgttc atggtaggga
    65281 cttatgaaag ctttactgac aaaaaagaaa acagtttaca aagaaaaatg atggaggagc
    65341 aaacatggca caaaaaggag taagccttat caaggcagca tttgatacag ataactttct
    65401 catgcgtttt agtgagaagg tcttggacat cgtgacagcc aatcttcttt ttgtcgtctc
    65461 ttgtttgccc atcgtgacga ttggagtggc taaaatcagc ctctacgaga ccatgttcga
    65521 agttaagaag agcagacggg tgcctgtttt taaaatctat ctaagatctt tcaagcaaaa
    65581 tctgaaacta ggtcttcagt taggtctgct tgagttgggc attgtttcat taagcctcct
    65641 agatctttat ctcttttggg gtcaaacagc tctgcccttt caattgctga aagctatttg
    65701 tctaggcatt ctgattttcc ttacgattgt gatgttggct agctatccaa tcgcggcacg
    65761 ttatgattta acttggaaag aaattcttca aaaaggattg atgttggcta gttttaactt
    65821 tccttggttc ttcctcatgt tagccattct tgtcctcatt gtgatggttc tttatctgtc
    65881 tgccttcagt ctactcttag gtggctcagt cttcctgctt tttgggtttg gactattggt
    65941 ctttatccag actggattga tggagaaaat tttcgcaaaa taccaatagg agccttattt
    66001 ctgaaactac tttcaaaggc tccaaacgct attctataag cgagaaacta aaatctaagt
    66061 gtctataaga tattgaaagc cttttcggta aagtgtatac taaagaagta aagaaaaatc
    66121 tgctttagca gaaaataaaa ataataggag aaaatctatg tcagatttga aaaaatacga
    66181 aggtgtcatt ccagccttct acgcatgtta tgatgagcaa ggagaagtaa gtccagagcg
    66241 tacgcgtgcc ttggttcaat acttcattga taaaggtgtt caaggtcttt atgtcaatgg
    66301 ttcttctggt gaatgtatct accaaagcgt tgaagatcgc aagttgattt tggaagaagt
    66361 catggcggta gccaaaggta aattgaccat tattgcccat gttgcttgca ataatactaa
    66421 agatagtatg gaacttgctc gccatgctga aagcttggga gtagatgcta ttgcaacgat
    66481 tccaccaatt tacttccgct tgccagaata ctcagttgcc aaatactgga acgatattag
    66541 ttctgcagct ccaaacacag actacgtgat ttacaacatt cctcaattgg caggggttgc
    66601 tttgactcca agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg gtgttaagaa
    66661 ctcttctatg ccagttcaag atatccaaac ctttgtcagc cttggcgggg aagaccatat
    66721 tgtctttaac ggtccagatg aacagttcct aggtggccgc ctcatgggtg ctaaggctgg
    66781 tatcggtggt acttatggtg ctatgccaga actcttcttg aaactcaatc agttgattgc
    66841 ggataaggac ctagaaacag cgcgtgaatt gcagtatgct atcaacgcaa tcattggtaa
    66901 actcacttct gctcatggaa atatgtacgg tgtcatcaaa gaagtcttga aaatcaatga
    66961 aggcttgaat attggatctg ttcgttcacc attgacacca gtaactgaag aagatcgtcc
    67021 agttgtagaa gcggctgcag ccttgattcg tgaaaccaag gagcgcttcc tctaatctaa
    67081 aaggaggtat ttatgacata ctacgttgca attgatatcg gtggaactaa catcaagtat
    67141 ggtttggttg atcaagaggg gcaacttctt gaatcgcatg aaatgccaac tgaggcgcat
    67201 aagggtggac ctcatatctt acaaaagacc aaagatatcg tagctagtta tttagaaaaa
    67261 ggcccagtag caggtgttgc catatcttct gctgggatgg tggatccgga taagggtgag
    67321 attttctatg ctgggccgca aatccctaac tacgcaggca cccagttcaa aaaggaaatc
    67381 gaagaaagct ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc aggtcttgct
    67441 gaggcagtat ctggttcagg caagggagca agtgtgacac tttgcttgac cattggaaca
    67501 ggtatcggtg gttgcttgat tatggatagg aaagtcttcc atggttttag taattcagcc
    67561 tgtgaagtcg ggtatatgca tatgcaggat ggagcttttc aagacttggc ttctacaaca
    67621 gctttagtga aatatgtagc tgaagcccat ggagaagatg ttgatcagtg gaatggccga
    67681 cgtatcttta aggaagctac tgaaggaaac aaaatctgca tggaaggtat tgaccgtatg
    67741 gttgactatc taggaaaagg tctggcaaat atttgctacg ttgccaatcc agaagtggtt
    67801 attcttggtg gtggtatcat ggggcaagag gctatcctca aacctaagat ccgcacagcc
    67861 ttgaaagagg ctttggtacc aagtttagca gaaaaaacac gattagaatt tgcccatcac
    67921 caaaatacag cagggatgtt gggtgcatat tatcatttta agacaaaaca atcctagttt
    67981 ggctcagcca aactaggatt ttcttacacg tttttgtcta cgatagccgt tgagtttttt
    68041 attttcccag tagctattaa agattttttc cttgctttcg cgattgattt ccaaaaagta
    68101 ggcataaatc aaatcgataa agaagagcat aggaagttga gcggatattc gttggatata
    68161 ggagggttgg ctgtgggtgg ctacaagaac agtctctgta taggtctggc tatctttatt
    68221 gggaacactt gtaaagagta cagtctttgc ccccatctcc ttggcatcta atagactatc
    68281 taaaatagaa ggagttgagc ctgaaagtga gaagcccagt actagacaat tttcatccat
    68341 gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga ccacacctag
    68401 tcgcataaaa cgtaatttca tttcacgggc gacgaggcca gaactccctg ttccgaagaa
    68461 gtagatacgc tcagcatctt cgattagctg ggcaattcgt tctagttgga tttcgtcaat
    68521 caagtcttgt gtttgttccc tcatgttgct ataacttctg aggactcgtt tggtcagtgg
    68581 actgtgcttg gagacttggt tggcttgatt ttctgcctga tgttggtatt ggaaaataaa
    68641 ttctcggtag ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag cttgagaaat
    68701 atgtaatttt tgggtgactt gttgagaaga taaatcatct gtaatcgttt cagcttgcaa
    68761 aaaatagcga gcgatttctt gttctaggtc tgtcatttct tcaaaatgtg aatcaatgat
    68821 agttgcgata tctggtttgt ccatagggaa agctccttta catgagtcat actggaagac
    68881 tagatcaggg aatagtcaca cttcattata acacataata taaggataga taaataaaaa
    68941 cgcatctctg ttttaaaaac gaaaaaatcg aaaaagcttc tttcttttcc ataattttct
    69001 actcaaattg tggtacaatt aagagtaaga ttttaagtta gaaatgagac tgatttgtat
    69061 gagaaaattt aacagccatt cgattccgat tcggcttaat ttattgtttt caatcgtcat
    69121 tttactcttt atgaccatta ttggtcgttt gttgtatatg caggttttga acaaggattt
    69181 ttacgaaaaa aagctagcct cagctagtca gaccaagatt acaagcagtt cagcccgtgg
    69241 ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc aggttgtttc
    69301 ctttacgcgt agcaataaaa tgacggctac agacttaaaa gaaacagcta aaaagttact
    69361 gacttatgtg agcatcagtt ctccaaattt gacagaacgc cagctggcgg attactattt
    69421 ggctgatcct gaaatctata aaaaaacagt ggaagctctc ccaagcgaga aacgcttgga
    69481 ttcagatggc aatcgtctat ccgaatcaga actgtataac aatgcggtcg atagtgtaca
    69541 aacgagtcaa ctaaactata cagaggatga aaagaaagaa atctatcttt ttagtcagtt
    69601 aaatgctgtt ggaaactttg cgacaggaac cattgcgaca gatcctctaa atgattctca
    69661 ggtggctgtt attgcctcta tttcaaagga gatgcctggc attagtattt ctacttcttg
    69721 ggatagaaag gttttggaaa cttccctttc ttctatagtt gggagtgtat ccagtgaaaa
    69781 agctggtctc ccagcggaag aagcagaagc ctatcttaaa aaaggctatt ctctaaatga
    69841 tcgtgtagga acctcctatt tggaaaagca atatgaagag accttacaag gaaaacgctc
    69901 ggtaaaagaa atccatctgg ataaatatgg caatatggaa agcgtggata caattgagga
    69961 aggtagtaag ggaaacaata tcaaactgac cattgatttg gctttccaag atagcgtgga
    70021 tgctttactg aaaagttatt tcaattctga gctagaaaat ggtggagcca agtattctga
    70081 aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta tgtcagggat
    70141 taaacatgac ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg taaccaatgt
    70201 ctttgttcca ggttcggttg tcaaggcggc gaccatcagc tcaggttggg aaaatggagt
    70261 cttgtcagga aaccagacct tgacagacca gtccattgtc ttccaaggtt cagctcccat
    70321 caattcttgg tatactcagg cttacggttc attccctatc acagcggtcc aagctctgga
    70381 gtattcatca aatacctata tggtccaaac agccttaggt cttatggggc aaacctatca
    70441 acccaatatg tttgtcggca ccagcaatct agagtctgct atggagaaac tgcgttcaac
    70501 ctttggcgaa tatggcttgg gtactgcgac aggaattgac ctaccagatg aatctactgg
    70561 atttgttccc aaagagtata gctttgctaa ttacattact aatgcctttg ggcagtttga
    70621 taactatacg ccgatgcagt tggctcagta tgtagcaact attgcaaata atggtgttcg
    70681 tgtggctcct cgtattgttg aaggcattta tggtaataat gataagggag gactgggtga
    70741 cttgattcag caactgcaac cgacagagat gaataaggtc aatatatccg actccgatat
    70801 gagcatcttg caccaaggtt tttatcaggt tgcccatggt actagtggat tgacaactgg
    70861 acgtgccttt tcaaatggtg ccttggtatc cattagcgga aaaacaggta cagccgaaag
    70921 ctatgtggca gatggtcagc aagcaaccaa taccaatgcg gtggcctatg ccccatctga
    70981 taatccccaa atcgctgtcg cagtggtctt tcctcataat accaatctaa caaatggtgt
    71041 aggaccttcc attgcgcgtg acattatcaa tctgtatcaa aaataccatc caatgaacta
    71101 gaaaggaaat tatgctttat ccaacaccta ttgccaagtt gattgacagt tattctaagt
    71161 taccaggtat cgggattaag acggctacgc gtctggcctt ttatacgatt gggatgtctg
    71221 ctgatgatgt caatgaattt gcaaaaaatc tcctttctgc taagagagaa ttgacatatt
    71281 gttctatttg tggacgtttg acagacgacg atccttgttc tatctgtact gattcgactc
    71341 gtgaccagac aacaatttta gttcttgagg atagtagaga tgtggcagcc atggaaaata
    71401 tccaagaata ccatggactc tatcatgtcc tgcatggcct catttctcct atgaatggta
    71461 tcagtccgga cgatatcaat cttaagagcc ttatgactcg tcttatggat agtgaggttt
    71521 cagaagtgat tgtggcgact aatgctacag cggatggtga agcgacctcc atgtatcttt
    71581 cacgtttgct caagccggct ggtatcaagg ttacgcgtct agcacgaggt ctcgctgtgg
    71641 gagcggacat tgagtatgcg gacgaagtga cactcttacg agcgattgaa aatcggacag
    71701 agttgtaagt gtaggcaaat ttacgaactc cattcattta taaaaaatca aagaggctga
    71761 aaatcgttcc tatcggcctc tttttgtata gtgtgatgag taggatcagg ttcaagtttt
    71821 aaaaaaccaa gcaaatatga tatactaaag agcgagtatt ctagtagaat taggacaaat
    71881 aatatgaaac aaacgattat tcttttatat ggtggacgga gtgcggaacg cgaagtctct
    71941 gtcctttcag ctgagagtgt catgcgtgcg gtcaattacg accgtttcat agtcaagact
    72001 ttctttatca gtcagtcagg tgactctatc aaaacgcagg aatttagtca tgctccgggg
    72061 caagaagacc gtctcatgac caatgaaacc attgattggg ataagaaagt tgcaccaagt
    72121 gctatctacg aagaaggtgc agtggtcttt ccagtccttc acgggccaat gggagaagat
    72181 ggctctgttc aaggattctt ggaagttttg aaaatgcctt acgttggttg caacattttg
    72241 tcatcaagtc ttgccatgga taaaatcacg actaagcgtg ttctggaatc tgctggtatt
    72301 gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa aatagctgaa
    72361 gtggaagaaa aattggctta tccagtcttc actaagccgt caaacatggg gtctagtgtc
    72421 ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact tgccttccga
    72481 tatgacagcc gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga ggttggcctc
    72541 ttgggtaact acgatgtcaa gagcacgcta cctggagaag ttgtcaagga cgttgccttt
    72601 tatgactacg atgccaagta tattgataac aaggttacta tggatattcc tgccaaaatc
    72661 agtgatgatg tggtggctgt catgcgtcaa aatgcagaag cagccttccg tgccattggt
    72721 ggccttggtc tatctcgttg cgatttcttc tatacagata agggagagat ttttctcaac
    72781 gagctcaata ccatgccagg tttcacccag tggtctatgt acccactact ttgggaaaat
    72841 atggggatca gctacccaga actaatcgag cgtttggttg accttgccaa ggaaagtttt
    72901 gacaagcgcg aagcgcattt gatataaaat gaaagagagg gtagaagcca gaaccatcac
    72961 tgcaaggtga ctagagttct cggacttcgc ccctttttaa aggagtagaa atgaaattaa
    73021 caatctatga agttgcccaa gctgttggag ctaaaaatga tgttagtctt tttgcggacg
    73081 cccagttaga aaaggctgag tttgacagtc gattgattgg gactggagat ttatttgtgc
    73141 cacttaaagg tgcgcgtgat ggccatgact ttattgaaac agcctttgaa aatggtgcag
    73201 cagtaacctt gtctgagaaa gaggtctcaa atcatcctta cattctagta gatgatgttt
    73261 tgacagcctt tcaatcctta gcatcctact atcttgaaaa aacgactgtt gatgtctttg
    73321 ctgttacagg ttcaaatggc aagacaacga ctaaggatat gttggcgcat ttactgtcaa
    73381 caagatacaa gacctacaaa acacaaggca attacaataa tgagattggc cttccttaca
    73441 cagttcttca tatgcctgaa ggaacagaaa agttggtttt ggagatggga caggatcact
    73501 tgggagatat tcatctcttg tctgaattgg ctcgtccaaa aacagccatc gtgaccttgg
    73561 ttggagaagc tcatttggcc tttttcaaag atcgttctga gattgctaaa ggaaaaatgc
    73621 aaattgcaga cggaatggct tcaggttcct tgcttttaac gccggctgac cctatcgtag
    73681 aggactattt gccaactgat aaaaaggtgg tccgttttgg gcaaggggca gagttggaaa
    73741 tcacagactt ggttgagcgt aaggacagtc tgacctttaa ggctaatttc ttggaacaag
    73801 cccttgattt gccagtgact ggtaagtaca atgctaccaa tgctatgatt gcgtcctatg
    73861 ttgccctaca agaaggagtt tcagaggagc aaattcatca ggccttccaa ggtcttgaat
    73921 tgacgcgtaa tcgtactgag tggaagaaag cagccaatgg agcagatatc ctgtcagacg
    73981 tatataatgc caatccaact gctatgaagc tgattttaga gactttctct gccattccag
    74041 ccaatgaagg tggcaagaaa attgcagtgt tggcggatat gaaggagctt ggtgaccagt
    74101 ctattcaact ccataaccag ataattttga gcctttctcc agatgtgctt gataccgtta
    74161 ttttctatgg agaagacatt gctgaattag cccaacttgc tagtcaaatg ttcccaatcg
    74221 gacacgttta ttacttcaag aaaacagaag accaagacca atttgaagac ctagttaagc
    74281 aggtcaaaga aagccttggg gctcatgacc aaatcctgct caaaggctct aactctatga
    74341 atctagccaa gttggtagaa agtttagaaa atgaagacaa gtgattttgt caagtatttg
    74401 caaagaatga ttgccattac agatactggc ttaaccttta caaaagatcc gtttgaccgt
    74461 gagcgctacg aagacttgcg agacttttta tctgaaatgt tgaatcaagc atcagacctt
    74521 gattccgaag aagtggcaga agtcttgaag ccaacttctg cttatgcgac tccgttaatg
    74581 gacgtccgtg cttggattgt tgaggacgaa aagatttgtc tggttagggg acaaggagag
    74641 gatagttggg ctttgccagg tggctttggt gaggttggct attctccaac agaaaatatt
    74701 ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag ttgaaagact gctagctgtt
    74761 tttgatacca atcgtttcca actacagagc aaacagtata caaagtttgt ttttggatgt
    74821 aagcttctcg atggacaatt ccaagaaaat caagaaattg ctgaccttca attttttgcc
    74881 attgaccaac tgccgaactt atctgaaaaa cgcattacca aggagcaaat agagcttctt
    74941 tggcaggttt atcaaggtca tagggggcaa tatcttgact aagaagatga ttatcgtatt
    75001 tctaaatcca tttttgacaa ctagcatggt ataataatat gcaggaaaat tttgaattat
    75061 gaggaagact agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc
    75121 aaatttgacc ttttttggta tgttagccta tttacgctct tagccttaac cttttataca
    75181 gcccatcgct atcgtgaaaa gaaggtttac caacgatttt tccaaatctt gcagactgtt
    75241 cagttaatcc ttctttatgg ttggtactgg gtcaatcata tgccactgtc agaaagccta
    75301 cccttttacc attgccgtat ggctatgttt gtggtactct tgcttcctgg tcaatccaaa
    75361 tataaacaat actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca
    75421 gtgccagatg cttacccttt tccacatatc accattctat cctttatctt tggtcattta
    75481 gcactcttgg ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat
    75541 gtgaagggaa tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaatttg
    75601 gtgacaggtg gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta
    75661 gtagctaatt atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa
    75721 atcttagaat tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac
    75781 agagctttct tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct
    75841 gaatagacaa actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt
    75901 ttttgtgtta taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa
    75961 gtgcgaaact tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag
    76021 gtctagatat tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat
    76081 taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg
    76141 atattgatgc agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag
    76201 gcatttcgat taaatcagtg aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa
    76261 ctcaggggat gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa
    76321 atgttgtcaa atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta
    76381 ttcctgaaga atttattgtg gatggtttcc aagggattcg tgacccacgt ggcatgatgg
    76441 gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt
    76501 tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag
    76561 caatggttca gtctgttttg aacgaagggg aacgtgaatt tggtgctaca gtgattgata
    76621 tgggggcagg tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata
    76681 ttctccaaga aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc
    76741 gcaaattagc ggaaggcttg aaactgaatt acggggaagc ctatccgcct cttgcaagca
    76801 aagaaacctt ccaagtagag gttattggag aagtagaagc agtcgaagtg acggaagcct
    76861 acttgtcaga aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat
    76921 tagatagaag gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca
    76981 ttttaccagg tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg
    77041 ttccaaatca agttggtatc cgtaatccag cctttgcgca tgtgattagt ttatcagaat
    77101 ttgcgggtca attaacagaa gttaatcttt tggctcaggg agcgataaaa ggtgagaatg
    77161 acttaagtca tcagccaatt agttttggtg ggatgttgca aaaaacagct cagtttgtac
    77221 aatcaacgcc tgttcaacca gctcctgctc cagaagtaga gccggtggcg cctacagaac
    77281 caatggcgga tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg
    77341 gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt
    77401 gatacagctg ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc
    77461 aatgccatca accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac
    77521 acagatgtac aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa
    77581 ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa
    77641 agcgaagaaa cactgacgga agctattagt ggtgccgata tggtcttcat cactgctggt
    77701 atgggaggag gctctggaac tggagctgct cctgttattg ctcgtatcgc caaagattta
    77761 ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga
    77821 caatttgctg tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc
    77881 tcaaacaaca atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc
    77941 gaagcggata acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca
    78001 ggattgatta accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct
    78061 cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca
    78121 atctattcac cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt
    78181 actggtggtc ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag
    78241 gcagcaggtc aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat
    78301 gaaattcgtg taacagttgt tgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg
    78361 gctccacaag ctagaactgc tactaactac cgtgagacag tgaaaccagc tcattcacat
    78421 ggctttgatc gtcattttga tatggcagaa acagttgaat tgccaaaaca aaatccacgt
    78481 cgtttggaac caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt
    78541 gttcgtacaa cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa
    78601 gatgaagatg aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa
    78661 agaaaataca gaacttgttt ttcgagaagt tgcagaggct agtctgagtg ctaatcgaga
    78721 gagtggttcg gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc
    78781 cttgcttccg ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa
    78841 atatgaagct ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg
    78901 taaggtgaaa gatgtcattc aatacgttga ttatttccat gcattggact cagtaaagct
    78961 agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat
    79021 ttctaaagaa gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga
    79081 gttagccaga ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc
    79141 tagcagtgag cagttgaaag agattttcaa ggcgacccaa gatttacaaa gagaaattca
    79201 agagaaacaa attccaaata tgcctatgac cgagttaagt atgggaatga gtcgtgatta
    79261 taaagaagcg attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta
    79321 ggagagaacc atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga
    79381 tgaggattca agtctccctt atgaaaaaag agatgagcct gtgtttactc cagtaaattc
    79441 ttcacaggaa ccggctctcc caatgaatca accttcacag tcggctggta caaaagagaa
    79501 caatatcacc agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac
    79561 ggataaggtc attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt
    79621 tgatttattg gcaggaaacg aaagtatctt gattgatttt cagtatatga cagaggtgca
    79681 ggctcgtcgt tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa
    79741 aaaggtagct tctaccatgt atttgttgac accagtgaat gttattgtaa atgttgaaga
    79801 tatccgttta ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag
    79861 agtacgataa tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg
    79921 attttggtag ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt
    79981 cgttggattg tagcgttggt gaaaccagtg cttgctccct tgcaacgcct gcctttacag
    80041 atagcgggtc ttgatttatc tgtttgggtt gcgattgttt tggttcgatt tttaggagaa
    80101 aacctagtgc gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca
    80161 tagaagatcg tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct
    80221 atgctccttt tttaactcct tttatcaatc ctcatcagga gaagctatta aagattttgg
    80281 ccaaaaccta tggtcttgct tgtagcagta gtggggaatt cgtatcgagt gagtatgttc
    80341 gagttttatt atacccagat tatttccaac cagagttttc agattttgaa atatctctcc
    80401 aggaaattgt gtattccaat aaatttgaat atttaacgca tgctaagatt ttagggacag
    80461 tcatcaatca attagggatt gaacggaaac tttttggaga tatcctagta gatgaagaac
    80521 gggcgcagat tatgattaat cagcagtttc ttcttctctt tcaagatgga ctaaagaaaa
    80581 ttggtcgtat acctgtttcg ctggaggaac gtcctttcac cgagaaaata gataagctag
    80641 aacagtatcg agaactggat ttatctgtgt ctagttttcg attagatgtt cttttatcaa
    80701 atgttttgaa actatctagg aatcaagcaa accagttgat tgaaaagaaa cttgtccaag
    80761 taaattatca tgtggtagac aaatcagatt acactgttca agttggagac ttgattagtg
    80821 tgagaaaatt tggtcgcttg agattacttc aagataaggg acaaacgaaa aaagagaaga
    80881 aaaaaataac cgtccagtta ttattaagta agtgaggaat agaatgccaa ttacatcatt
    80941 agaaataaag gacaagactt ttggaactcg attcagaggt tttgatccag aagaagtcga
    81001 tgaattttta gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga atcatgataa
    81061 aaatttgcgt attaagagtt tagaagagcg tttgtcttac tttgatgaaa taaaagattc
    81121 attgagccag tctgtattga ttgctcagga tacagctgag agagtgaaac aggcggcgca
    81181 tgaacgttca aacaatatca ttcatcaagc agagcaagat gcgcaacgct tgttggaaga
    81241 agctaaatat aaggcaaacg agattcttcg tcaagcaact gataatgcta agaaagtcgc
    81301 tgttgaaaca gaagaattga agaacaagag ccgtgtcttc caccaacgtc tcaaatctac
    81361 aattgagagt cagttggcta ttgttgaatc ttcagattgg gaagatattc tccgtccaac
    81421 agctacttat cttcaaacca gtgatgaagc ctttaaagaa gtggttagcg aagtacttgg
    81481 agaaccgatt ccagctccaa ttgaagaaga accaattgat atgacacgtc agttctctca
    81541 agcagaaatg gaagaattac aagctcgtat tgaggtagcc gataaagaat tgtctgaatt
    81601 tgaagctcag attaaacagg aagtggaaac tccaactcct gtagtgagtc ctcaagttga
    81661 agaagagcct ctgctcgtcc agttggccca atgtatgaag aaccagaagt agctccagtg
    81721 catccgacag gtccaacacc agctacagaa actgttgatt cagcaccggg atttgaagca
    81781 ccgcaagaat ctgttacaat tttataagaa atattctgag aacaatatct tatccttata
    81841 ttcccagcga gcaggagatg gtgtgagtcc tgcattccct atcgataaga ttatcctctc
    81901 aaactatcaa gtctgaatct agtaagattt gacgttcccc acgttacggg ataagaggga
    81961 gaaagactaa aactttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt
    82021 cgtggttttt aatttgttat tatttataaa ggagatacca tgaaactaaa agataccctt
    82081 aatcttggga aaacagcttt cccaatgcgt gcaggccttc cgaccaaaga gccagtttgg
    82141 caaaaggaat gggaagatgc aaaactttac caacgtcgtc aagaactaaa tgaagggaaa
    82201 ccgcattttg tcttgcatga tggccctcca tacgcaaacg gaaatatcca cgttggacat
    82261 gccatgaatc atatctcaaa agatatcatc attcgttcta agtctatgtc aggttttaac
    82321 gcaccttata tcccaggttg ggatactcat ggtctgccaa tcgagcaagt tttggcaaag
    82381 caaggtgtga agcgcaaaga aatggacttg gttgagtact tgaaactctg tcgtgagtac
    82441 gctctttctc aagtttataa acaacgtgat gatttcaaac gcttggggat gtcaggtgac
    82501 tgggaaaatt tatatgtgac tttaactcca gactatgaag cagcccaaat ccgtgtcttt
    82561 ggtgagatgg ctaataaggg ttatatctac cgtggtgcta agccagttta ctggtcatgg
    82621 tcatctgagt cagcccttgc cgaagcggaa attgaatacc atgatttggt ttcgacttca
    82681 ctttattatg ccaataaggt aaaagatggc aaaggtatcc tagatacaga tacttatatc
    82741 gtagtctgga caacaactcc atttaccatc acagcttctc gtggtttgac tgttggtgca
    82801 gatattgatt acgttttggt tcaacctgct ggtgaaactc gtaagtttgt cgttgctgca
    82861 gaattgttga ctagcttgtc tgagaaattt ggctgggctg atgttcaagt gttggcaact
    82921 taccgtggtc aagaactcaa ccacatcgta acagaacacc catgggatac agctgtagat
    82981 gagttggtaa tccttggtga tcacgttacc actgactctg gtacaggtat cgtccataca
    83041 gcccctggtt ttggtgagga cgactacaat gttggtattg ctaatggtct tgaagtcgca
    83101 gtgactgttg acgaacgcgg tatcatgatg gcgaatgctg gtcctgagtt tgaaggtcag
    83161 ttctacgaca aggttgtacc aactgttatt gaaaaacttg gtaacctcct tctagcccaa
    83221 gaagaaatct ctcactcata cccatttgac tggcgtacta agaaaccaat catctggcgt
    83281 gcagttccac aatggtttgc ctcagtttca aaattccgcc aagaaatctt ggatgctatt
    83341 gataaagtta aattccatac agaatggggt aaagtacgtc tatataatat gattcgtgac
    83401 cgtggtgact gggttatctc tcgtcaacgt gcttggggtg ttccacttcc aatcttctat
    83461 gcagaagacg gtacagctat catgacagct gagactattg aacatgtggc gcaactcttt
    83521 gaagtacatg gttcaagcat ttggtgggaa cgtgatgcca aggacctctt gccagaagga
    83581 tttacacatc caggttctcc aaatggggag ttcaagaaag aaacagatat tatggatgta
    83641 tggtttgact caggttcatc atggaatggt gttttggtaa atcgtccaaa tctgacttat
    83701 ccagctgacc tttacctaga aggttctgac caataccgtg gttggtttaa ctcatcactt
    83761 atcacatctg ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt
    83821 gcccttgatg gtaaaggtga gaagatgtct aaatctcttg gaaataccat tgctccaagc
    83881 gatgttgaaa aacaattcgg tgctgaaatc ttgcgtctct gggtaacaag tgttgactca
    83941 agcaatgacg tgcgtatctc tatggatatt ttgagccaag tttctgaaac ttaccgtaag
    84001 attcgtaaca ctcttcgttt cttgattgcc aatacatctg actttaaccc agctcaagat
    84061 acagtcgctt acgatgagct tcgttcagtt gataagtaca tgacgattcg ctttaaccag
    84121 cttgtcaaga ccattcgtga tgcctatgca gactttgaat tcttgacgat ctacaaggcc
    84181 ttggtgaact ttatcaacgt tgacttgtca gccttctacc ttgattttgc caaagatgtt
    84241 gtttacattg aaggtgccaa atcactggaa cgccgtcaaa tgcagactgt cttctatgac
    84301 attcttgtca aaatcaccaa actcttgaca ccaatccttc ctcacactgc ggaagaaatt
    84361 tggtcatatc ttgagtttga aacagaagac ttcgtccaat tgtcagagtt accagaggct
    84421 caaacttttg ctaatcaaga agaaatcttg gatacatggg cagccttcat ggacttccgt
    84481 ggacaagcac aaaaagcctt ggaagaagct cgtaatgcaa aagttatcgg taaatcactt
    84541 gaagcacact tgacagttta tcaaaatgaa gttgtgaaaa ctctactcga agcagtaaac
    84601 agcaatgtag ctcaactttt gatcgtgtct gagttgacca tcgtagaagg accagctccg
    84661 gaagctgccc ttagcttcga agatgtagcc ttcacagttg aacgtgctac tggtgaagta
    84721 tgtgaccgtt gccgtcgtat cgacccaaca acagcagaac gcagctacca ggcagttatc
    84781 tgtgaccact gtgcaagcat cgtagaagaa aactttgcgg aagcagtcgc agaaggattt
    84841 gaagagaagt aaggttgaaa agtctagaga aaactcaatt tgagaagaaa agacaactaa
    84901 tcttatagtc tataaaacgc atagtatcac gtttttgaac acatgatatg atgcgttttt
    84961 tatttatttt aaaaatttgc gaggtatgac tttttatact caacaagaat caaagagaaa
    85021 cttagcaagc taacagtagt aagataaaat aggaatttga tattagggat aagattggta
    85081 aatagtgtaa tatttttaca acaataaatt tatatagtta tttctggttt ctgaaaagta
    85141 ttatattata ttttattt
//
LOCUS       DAVHSI010000003        80891 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.003, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000003 DAVHSI010000000
VERSION     DAVHSI010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80891
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.003"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(1..1708)
                     /locus_tag="VVR21_000166"
                     /pseudo
     CDS             complement(1..1708)
                     /locus_tag="VVR21_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808684.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
     gene            complement(1998..2135)
                     /locus_tag="VVR21_000167"
     CDS             complement(1998..2135)
                     /locus_tag="VVR21_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU6054127.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(2337..2924)
                     /locus_tag="VVR21_000168"
     CDS             complement(2337..2924)
                     /locus_tag="VVR21_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6054128.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            complement(3017..3160)
                     /locus_tag="VVR21_000169"
     CDS             complement(3017..3160)
                     /locus_tag="VVR21_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054129.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            complement(3173..3553)
                     /locus_tag="VVR21_000170"
     CDS             complement(3173..3553)
                     /locus_tag="VVR21_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6054130.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLYN"
     gene            complement(3546..3869)
                     /locus_tag="VVR21_000171"
     CDS             complement(3546..3869)
                     /locus_tag="VVR21_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054131.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSHD"
     gene            complement(3883..4131)
                     /locus_tag="VVR21_000172"
                     /pseudo
     CDS             complement(3883..4131)
                     /locus_tag="VVR21_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(4131..4301)
                     /locus_tag="VVR21_000173"
     CDS             complement(4131..4301)
                     /locus_tag="VVR21_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054132.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            complement(4500..4868)
                     /gene="rplL"
                     /locus_tag="VVR21_000174"
     CDS             complement(4500..4868)
                     /gene="rplL"
                     /locus_tag="VVR21_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU6054133.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(4944..5444)
                     /locus_tag="VVR21_000175"
     CDS             complement(4944..5444)
                     /locus_tag="VVR21_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU6054134.1"
                     /translation="MSEAIIAKKAELVDVVAGKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(5483..5618)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(5694..6953)
                     /locus_tag="VVR21_000176"
     CDS             complement(5694..6953)
                     /locus_tag="VVR21_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU6054135.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIVDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSNDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(7255..9003)
                     /locus_tag="VVR21_000177"
     CDS             complement(7255..9003)
                     /locus_tag="VVR21_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054136.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGIIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(9005..10729)
                     /locus_tag="VVR21_000178"
     CDS             complement(9005..10729)
                     /locus_tag="VVR21_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054137.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(10787..11725)
                     /gene="msrB"
                     /locus_tag="VVR21_000179"
     CDS             complement(10787..11725)
                     /gene="msrB"
                     /locus_tag="VVR21_000179"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6054138.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(11867..11944)
                     /locus_tag="VVR21_000180"
                     /pseudo
     CDS             complement(11867..11944)
                     /locus_tag="VVR21_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12020..12889)
                     /locus_tag="VVR21_000181"
     CDS             complement(12020..12889)
                     /locus_tag="VVR21_000181"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU6054139.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(12891..14177)
                     /locus_tag="VVR21_000182"
     CDS             complement(12891..14177)
                     /locus_tag="VVR21_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU6054140.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVLAELKKVSEFDLLNTFKVLGE"
     gene            complement(14328..15065)
                     /gene="mecA"
                     /locus_tag="VVR21_000183"
     CDS             complement(14328..15065)
                     /gene="mecA"
                     /locus_tag="VVR21_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU6054141.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(15265..16299)
                     /locus_tag="VVR21_000184"
     CDS             complement(15265..16299)
                     /locus_tag="VVR21_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6054142.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(16328..17761)
                     /locus_tag="VVR21_000185"
     CDS             complement(16328..17761)
                     /locus_tag="VVR21_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU6054143.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(17777..18763)
                     /locus_tag="VVR21_000186"
     CDS             complement(17777..18763)
                     /locus_tag="VVR21_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6054144.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(18765..19868)
                     /locus_tag="VVR21_000187"
     CDS             complement(18765..19868)
                     /locus_tag="VVR21_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6054145.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKNVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(19858..20703)
                     /locus_tag="VVR21_000188"
     CDS             complement(19858..20703)
                     /locus_tag="VVR21_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6054146.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(20982..22256)
                     /gene="psr"
                     /locus_tag="VVR21_000189"
     CDS             complement(20982..22256)
                     /gene="psr"
                     /locus_tag="VVR21_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU6054147.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(22253..23101)
                     /gene="pheA"
                     /locus_tag="VVR21_000190"
     CDS             complement(22253..23101)
                     /gene="pheA"
                     /locus_tag="VVR21_000190"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU6054148.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(23098..23574)
                     /locus_tag="VVR21_000191"
     CDS             complement(23098..23574)
                     /locus_tag="VVR21_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU6054149.1"
                     /translation="MAKVLLGFMGAGKSTIARGLNPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(23567..24850)
                     /gene="aroA"
                     /locus_tag="VVR21_000192"
     CDS             complement(23567..24850)
                     /gene="aroA"
                     /locus_tag="VVR21_000192"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU6054150.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(24942..25280)
                     /locus_tag="VVR21_000193"
     CDS             complement(24942..25280)
                     /locus_tag="VVR21_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU6054151.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(25291..26394)
                     /locus_tag="VVR21_000194"
     CDS             complement(25291..26394)
                     /locus_tag="VVR21_000194"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU6054152.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(26404..27570)
                     /gene="aroC"
                     /locus_tag="VVR21_000195"
     CDS             complement(26404..27570)
                     /gene="aroC"
                     /locus_tag="VVR21_000195"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU6054153.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(27580..28647)
                     /locus_tag="VVR21_000196"
     CDS             complement(27580..28647)
                     /locus_tag="VVR21_000196"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU6054154.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKKELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(28666..29520)
                     /locus_tag="VVR21_000197"
     CDS             complement(28666..29520)
                     /locus_tag="VVR21_000197"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU6054155.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMILLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(29510..30187)
                     /locus_tag="VVR21_000198"
     CDS             complement(29510..30187)
                     /locus_tag="VVR21_000198"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU6054156.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(30184..31347)
                     /locus_tag="VVR21_000199"
     CDS             complement(30184..31347)
                     /locus_tag="VVR21_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU6054157.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDREVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(32032..33666)
                     /locus_tag="VVR21_000200"
     CDS             complement(32032..33666)
                     /locus_tag="VVR21_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054158.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(33647..34396)
                     /locus_tag="VVR21_000201"
     CDS             complement(33647..34396)
                     /locus_tag="VVR21_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054159.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            34575..36029
                     /locus_tag="VVR21_000202"
     CDS             34575..36029
                     /locus_tag="VVR21_000202"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU6054160.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYRVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(36119..38737)
                     /gene="alaS"
                     /locus_tag="VVR21_000203"
     CDS             complement(36119..38737)
                     /gene="alaS"
                     /locus_tag="VVR21_000203"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU6054161.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(38759..39244)
                     /locus_tag="VVR21_000204"
     CDS             complement(38759..39244)
                     /locus_tag="VVR21_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU6054162.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFQLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(39519..39758)
                     /locus_tag="VVR21_000205"
     CDS             complement(39519..39758)
                     /locus_tag="VVR21_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054163.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSTMKIWDKKKNGSKKKYILKK"
     gene            complement(40027..41085)
                     /locus_tag="VVR21_000206"
     CDS             complement(40027..41085)
                     /locus_tag="VVR21_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6054164.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLNSKDLQQLEETVDKLYKLTPNIKAIVADEMKG
                     YMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNSAYAF
                     INFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYEKFDH
                     KWTGKYSDLFLQFKMYRK"
     gene            complement(41082..41855)
                     /locus_tag="VVR21_000207"
     CDS             complement(41082..41855)
                     /locus_tag="VVR21_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054165.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(41852..42658)
                     /locus_tag="VVR21_000208"
     CDS             complement(41852..42658)
                     /locus_tag="VVR21_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054166.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(42639..43796)
                     /locus_tag="VVR21_000209"
     CDS             complement(42639..43796)
                     /locus_tag="VVR21_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054167.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(43957..44862)
                     /gene="murB"
                     /locus_tag="VVR21_000210"
     CDS             complement(43957..44862)
                     /gene="murB"
                     /locus_tag="VVR21_000210"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU6054168.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(44974..45726)
                     /locus_tag="VVR21_000211"
                     /pseudo
     CDS             complement(44974..45726)
                     /locus_tag="VVR21_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(45736..46467)
                     /gene="budA"
                     /locus_tag="VVR21_000212"
     CDS             complement(45736..46467)
                     /gene="budA"
                     /locus_tag="VVR21_000212"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU6054169.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     VGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAIDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            46609..47880
                     /locus_tag="VVR21_000213"
     CDS             46609..47880
                     /locus_tag="VVR21_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU6054170.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(47900..48715)
                     /locus_tag="VVR21_000214"
     CDS             complement(47900..48715)
                     /locus_tag="VVR21_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6054171.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKAQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(48872..49525)
                     /gene="phoU"
                     /locus_tag="VVR21_000215"
     CDS             complement(48872..49525)
                     /gene="phoU"
                     /locus_tag="VVR21_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU6054172.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(49537..50295)
                     /gene="pstB"
                     /locus_tag="VVR21_000216"
     CDS             complement(49537..50295)
                     /gene="pstB"
                     /locus_tag="VVR21_000216"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6054173.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(50308..51111)
                     /gene="pstB"
                     /locus_tag="VVR21_000217"
     CDS             complement(50308..51111)
                     /gene="pstB"
                     /locus_tag="VVR21_000217"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU6054174.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(51122..52006)
                     /gene="pstA"
                     /locus_tag="VVR21_000218"
     CDS             complement(51122..52006)
                     /gene="pstA"
                     /locus_tag="VVR21_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU6054175.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(51996..52913)
                     /gene="pstC"
                     /locus_tag="VVR21_000219"
     CDS             complement(51996..52913)
                     /gene="pstC"
                     /locus_tag="VVR21_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU6054176.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(52913..53791)
                     /gene="pstS"
                     /locus_tag="VVR21_000220"
     CDS             complement(52913..53791)
                     /gene="pstS"
                     /locus_tag="VVR21_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU6054177.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(54365..55669)
                     /locus_tag="VVR21_000221"
     CDS             complement(54365..55669)
                     /locus_tag="VVR21_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU6054178.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLHYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKSSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(55670..56443)
                     /locus_tag="VVR21_000222"
     CDS             complement(55670..56443)
                     /locus_tag="VVR21_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU6054179.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRIYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(56433..56711)
                     /locus_tag="VVR21_000223"
     CDS             complement(56433..56711)
                     /locus_tag="VVR21_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU6054180.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(56711..57112)
                     /locus_tag="VVR21_000224"
     CDS             complement(56711..57112)
                     /locus_tag="VVR21_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU6054181.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(57322..57939)
                     /locus_tag="VVR21_000225"
     CDS             complement(57322..57939)
                     /locus_tag="VVR21_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU6054182.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(57929..58702)
                     /locus_tag="VVR21_000226"
     CDS             complement(57929..58702)
                     /locus_tag="VVR21_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU6054183.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(58713..59450)
                     /locus_tag="VVR21_000227"
     CDS             complement(58713..59450)
                     /locus_tag="VVR21_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU6054184.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSVVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(59455..60585)
                     /locus_tag="VVR21_000228"
     CDS             complement(59455..60585)
                     /locus_tag="VVR21_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU6054185.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(60669..61058)
                     /locus_tag="VVR21_000229"
     CDS             complement(60669..61058)
                     /locus_tag="VVR21_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6054186.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(61074..61457)
                     /locus_tag="VVR21_000230"
     CDS             complement(61074..61457)
                     /locus_tag="VVR21_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU6054187.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(61458..62246)
                     /locus_tag="VVR21_000231"
     CDS             complement(61458..62246)
                     /locus_tag="VVR21_000231"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU6054188.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            complement(62239..63174)
                     /locus_tag="VVR21_000232"
     CDS             complement(62239..63174)
                     /locus_tag="VVR21_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU6054189.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(63304..63480)
                     /locus_tag="VVR21_000233"
     CDS             complement(63304..63480)
                     /locus_tag="VVR21_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU6054190.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(63620..64327)
                     /locus_tag="VVR21_000234"
     CDS             complement(63620..64327)
                     /locus_tag="VVR21_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU6054191.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            64478..65506
                     /gene="queA"
                     /locus_tag="VVR21_000235"
     CDS             64478..65506
                     /gene="queA"
                     /locus_tag="VVR21_000235"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU6054192.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQRIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(66167..67294)
                     /locus_tag="VVR21_000236"
     CDS             complement(66167..67294)
                     /locus_tag="VVR21_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6054193.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(68025..68576)
                     /locus_tag="VVR21_000237"
     CDS             complement(68025..68576)
                     /locus_tag="VVR21_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054194.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(68926..69750)
                     /gene="nadE"
                     /locus_tag="VVR21_000238"
     CDS             complement(68926..69750)
                     /gene="nadE"
                     /locus_tag="VVR21_000238"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU6054195.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIVVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQELGADPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(69747..71207)
                     /locus_tag="VVR21_000239"
     CDS             complement(69747..71207)
                     /locus_tag="VVR21_000239"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU6054196.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ETHKNCVFLVDTYDTFRIGVPAAIQVACELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(71323..71811)
                     /locus_tag="VVR21_000240"
     CDS             complement(71323..71811)
                     /locus_tag="VVR21_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054197.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(71801..72010)
                     /locus_tag="VVR21_000241"
     CDS             complement(71801..72010)
                     /locus_tag="VVR21_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054198.1"
                     /translation="MVKNLKLKLARVELDLTQGQLADAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(72396..73124)
                     /locus_tag="VVR21_000242"
     CDS             complement(72396..73124)
                     /locus_tag="VVR21_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054199.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(73140..74018)
                     /locus_tag="VVR21_000243"
     CDS             complement(73140..74018)
                     /locus_tag="VVR21_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054200.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGQVG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRSLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTELDILILDEPTNGLD
                     IESSQIVLAVLKNLALHENVGILISSHKLEDIEEICERVLFLESGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSIKVVDF
                     KTKKETLKDIYLNRSK"
     gene            complement(74353..75081)
                     /locus_tag="VVR21_000244"
                     /pseudo
     CDS             complement(74353..75081)
                     /locus_tag="VVR21_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(75327..75638)
                     /locus_tag="VVR21_000245"
     CDS             complement(75327..75638)
                     /locus_tag="VVR21_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054201.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(75653..76939)
                     /locus_tag="VVR21_000246"
     CDS             complement(75653..76939)
                     /locus_tag="VVR21_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6054202.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            77563..77745
                     /locus_tag="VVR21_000247"
     CDS             77563..77745
                     /locus_tag="VVR21_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6054203.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            77755..78120
                     /locus_tag="VVR21_000248"
     CDS             77755..78120
                     /locus_tag="VVR21_000248"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU6054204.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            78117..79307
                     /locus_tag="VVR21_000249"
     CDS             78117..79307
                     /locus_tag="VVR21_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU6054205.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDENSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(79822..80814)
                     /locus_tag="VVR21_000250"
     CDS             complement(79822..80814)
                     /locus_tag="VVR21_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054206.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT        24536 a        17788 c        14593 g        23974 t
ORIGIN      
        1 gttgtaaaaa gttcaactgc ccgatctatc tccccaaatt cataaatgag ccagattgta
       61 ccaattttac catcaaaaag accagaaagg gacgatttct taaaattatt tactgcctca
      121 ttaataacct gtgttcgaat ctcataatag tcatcaaact tgaaattttt actttcttag
      181 ctagttgttg ataactccaa aggatagcta aatctgaaaa cgcaattcct tgattaaaat
      241 tcagaccata ataatgaact gggaagaatc ttgattgaaa ttctttacgc cactgtccat
      301 aagttagcgt aaaccctctc aataatttta taataaaatc ttgtatatct tgctcactct
      361 cgatagttct aatctcatgc atgggtttta aaactttttt cctggaaata ttctcaatct
      421 gtggacattt agaatctaga tatgacaata aactttctac ataatctata tgttctcttg
      481 tataacccaa agactcaaat agtttttttc cttctatcct ggtttgactt acatagttgt
      541 atgtcaaatc cgatgtagtt actagtagca tgtataaata atgagctatt tgtctaatac
      601 cataccaatc tatctcactg ggaagtgttt ctcgccatgc tctaaaacca ggggctgcaa
      661 ctttatgtac aactttttca tcattcgaaa agacagcctg ttcccagtct attatactaa
      721 tctcatcttc atccttaacc aagatatttt ctaaatgtaa atcttgatga tatacatttt
      781 cagaatgaaa cttattcgtt aaatcgatga gtttttctac tatctttgaa actctcaata
      841 gataatcttt ggtcttatca acaacttcat ataaaggaaa attattggta acccatctat
      901 ttagtggaac gcccttcata tgttcaattc ctaagaaggt gtgctcccag atcttaccgt
      961 accagtatat tttaggcatc tcactccatt catttagaat ttttagtgct ttgcactccg
     1021 aagctaatct ctctgaagaa taagtaccat caaatcctag acctgtatac ggtctagcct
     1081 cttttaaaat tatttttttc ccatcttctt ttagcctagc attatatatc ccaccactgt
     1141 ttgaaaatct aattgcatta tctataataa agggaaagtc tccctgtttt ttatctttct
     1201 tgtcaagcca tttattcaaa aagtcagggg gcactatacc ttttggaatt ttaaatactg
     1261 gtaaacgttc atctttaaca acttcatcgc caacaattaa ttcatcaata gcaaccttct
     1321 tttcatcatc ccttgacggc ctaaacacac catacctcag atatattggt gcttcatccc
     1381 aacgtttatc gcttaaaata tatggcccat tatattgctt taaggcactt tctaaccttt
     1441 gcaaaaccga ctctaattca ttttgatttg gataacatgt aataaattta ccagaaaatc
     1501 ctcgactaac caatttcccg tttcgcatga taaatttgtc ttctgtacta agatgtttaa
     1561 atggaattcg catttcatgg caaatttttg ctacatcttg taacaattca tgtgaactgt
     1621 tatactctga actaatgtgt attttccacc cttgtctttc aacaaatttt ccaatagggt
     1681 attgataaac ccactcatca ttattcatta cttcgtgcca attaaaaggc agacttactt
     1741 ggtactttat gctagtatct gtactataat cattattagt gaaaaagaaa ggatgctcca
     1801 aattgaaatt ataatccata acaaaatctc caagaaattt tatcaaactt aatatatcta
     1861 tagctagaca gacttattta aataaaaagg gagaatcctt tggattctcc ccatataagc
     1921 actaacattc caacgtgcac atattggaac gacatccata actccagaga atctctaaag
     1981 tttacaattt aaatgaatta acaattttcc caactaaaag cactccagtt accgcaacgg
     2041 tttgtactga atgtactaaa tcgcattcca tcaacttcat ctgtttcgtc aacttgaaca
     2101 gatactaatt gaagatttaa tacttcttct gccatagcta actcctccta tttaaatttt
     2161 taggattaag tgctttatcc accttcatta tactctctcc agcagtaaaa tgcaagcaat
     2221 gatacaatgt tgtcacatag aaaataatgt ttccgtaact tttcaaagta acttccatct
     2281 ctctcccaaa actggaagtt agttttagaa gttacctaaa aatcaggtta cctattttaa
     2341 aaaagcagca aactataaac tagtaggctc cacaccaaat gtagccccat actgccccat
     2401 aagtccaatt tgtagcgtac aagccctaaa aacatcccca gcgatacata caaacaccaa
     2461 gctataatgg ttcctggatg atgtgctaag gcaaataaaa cacttgtcaa agcaactcga
     2521 atatctaatt ttctaaccaa gttccataaa atttctctat acagaaattc ttcaaccata
     2581 ctcgcattga ttaaaaacaa taaaaatgaa aaccaaggaa cttgatgttg aagtccaatt
     2641 aagtttgctt gattcgtgct ttcttgcgca tggattaggc taaaacatag acttataatc
     2701 agtaggctaa cgaatccaat accaagccat ttcatcctag atttcatatt taccttatga
     2761 gcttgtttgc gttggccata catccataaa aaagaaatga gtgacgaacc atagagaatc
     2821 tgtagtatag ttaactcacc gatacaaaga aatttcaata agtatagaga taccaatagg
     2881 acatttactt gttggaatat ataaactgga attattcttt tcatagttac ctccgaaata
     2941 aatcttcata atctaaatct aatacctgca caatcctttc tacccatgga ctttgaggca
     3001 ttcattgttc catcttctag tggcgaatct tttgatacaa acgattcaat tcacttggat
     3061 agtgaaactc tcccgcaaac atttttctgg ttaactcaat ccagctgata tttctttcag
     3121 ccaaaataat ggacaagttc tcccaaaatc gttcagccat attgcttctc ctttagttat
     3181 ataaataatg tgtttgtgcc atgtaaatca attgtttcgt atctcttggc aatagagctc
     3241 tagcctcttc caaattcaga cttggataaa cccgcttatt tgaaaccaca agaggaagtc
     3301 tgatggttag ttcaggattt tttaaaatta tctcaacgaa atccgttaat cttagattgt
     3361 cacggttctt aaatcgtaat aaattgggag ataaaaactc aaaacaatct gaagaatagc
     3421 tcatcatctc aattaatttg tcctttgtca tttcagaaac tgaatgacaa gatacctcga
     3481 tgccatagtt ttggaagaag tctaaaagaa gttgatttct ttggctattt ttacttagat
     3541 agagatcaat catgggagac ctcccaaaga ttcggttcca tttgatattc tgacacgatt
     3601 aaggaatcta ataaatttgc gaagttaatc ggtttcttgt cttcatcata agcttttaca
     3661 gttacttggg ttgtaagtat tccctctttt ccctcggctc gatagccttg tccatataaa
     3721 acaaaaacga gattttgatg atcatctaca aaggcatcaa ccccattctt tatgtcttga
     3781 ctttcaagga attccataac gttttgaaga taggattcgt aaaatagtgg gtagttatgt
     3841 tttttatggt aatcatctaa aaatgtcact tcaaactcac atggagagta attttgactt
     3901 tgaacagcct aaaagtgcca tcaaatttga attggaataa atcaaataaa tagccccatc
     3961 ctcatcaatc caacctttgc tcaaagacaa ctccaaccga tcttttaaaa ctgagtaaac
     4021 caccttaacc tccagtttca tattcttata ccgttcactc tcaaataaaa gtttggggag
     4081 cttataataa cgctctgatg tctgatatta attagcggta atacgcttca ttattgtccc
     4141 tccaagacta aaattccaac atttccaaat tcatcaaatc ggattaaacc tacttgttcc
     4201 atttcatcaa ctaactgagt tgcttttaca atatcaactc ccatgatagt catgagatga
     4261 ctcttcacga attgacgtga tgactgtcct tccttttgca taattacctc cgaaacacaa
     4321 aaaaagggta gacaatctag tgtctacccc cgaaagttta ttaaaacaaa aatcctgcca
     4381 aagaattttt ggtagggttt ttggtaggaa actaaattaa tttatcagtt tctaaaatgt
     4441 gttcacgatt ctaaaaggct gatactatag tattccgaat tctaattggt atatgcctct
     4501 tatttaagag taactgaagc tccagcttct tccaatttag ctttgatttc ttcagcttct
     4561 gcagttgcaa cgccttcttt aacaagtgct ggtgcaccgt caacaagttc tttagcttct
     4621 ttaagaccaa gaccagtgat ttcacgtaca actttgataa cgccaacttt tttgtcgcct
     4681 gcagatgtca attcaacgtc gaatgaatct ttagcagcac cagcatcagc agcatcagct
     4741 gcagcaacag ctacaggagc agctgcagtt acaccaaatt cttcttcgat agcttttaca
     4801 aggtcgttca attcaaggat tgaagcttct ttaatttcag caataatgtt ttcaatgttc
     4861 aatgccattg ttatttcctc caaataagtt ttaaatttta taatagtttt tttcgtagct
     4921 aggctacgct atgtagctta agattaagcc gcgtcttctt tgctttctgc aaccgctttg
     4981 actgcaagag caacgttgcg cactggcgct tgaagtacag aaaggagcat agaaagaagt
     5041 ccttcgcggt ttggaagagt tgcaagtgca agaatctctt ctttagatgc gacagcgcct
     5101 tcgattgcac cacctttaat ttcaagtgct tcagcgtttt tagaaaagtc gttcaagatt
     5161 ttcgctggtg cgataacatc ttcattagaa aatgctactg cagatggtcc aacaaataca
     5221 gatgcaagat cttcaagacc agctttttca gctgcacgac gcaagattga gtttttaata
     5281 actttatact caacttcgct tccacgaagc tcacgacgaa gaactgtatc ttgctcaact
     5341 gtcaaaccac gagcgtctac aacgacgata gatgcagcag ctttcatttt tccagctact
     5401 acgtcaacta gttccgcttt tttagcaata attgcttcac tcattagtgt gttcacctcc
     5461 gtaattattt tgcttgggga atttttcaaa aagaaaaacg cgcccaaacc tagacacgaa
     5521 agtacaatac gcttcttttt acatgatacg tcttgtcctc ggtaggatat ttatgagtcg
     5581 agctccccta ctgtcttagg cagttttttt aaaccgtata taagtatagc atagtcaaaa
     5641 aaagaatgca agatttttgc aaactttttt taaaattttt cgtgattttt cttttaaagt
     5701 tctactgtca ggacttgacc ttgcttaaca acctgttctc cggcgatata aacatcatct
     5761 acatcattag atttaactgc ataaaccagg tgagacagca tattttcctg aggttggaga
     5821 tgaattttcc cttgtggttg aatgaccaga aaatctgctt gcttgccgac ttccagactt
     5881 cctatctgat tttccattcc aagggcctta gccccttcga ttgtcagtac cttgagagct
     5941 gtttcgattg gaaactggct ggcatcccca cttttcatct tctgaagaag agctgcagtc
     6001 cttccttcct caaacatatc tagattgtta ttggaagcaa ccgagtcagt cgcaattccg
     6061 actgctactc ccgctttttg gagctggata attggagcaa ttcctgatgc cagtttgagg
     6121 ttactgatag gattgtgggc gatagccact tgagaagatg ccaagcgttc aatttctctc
     6181 tcgtttaatt cgaccccgtg agcaaatacg gacggatgat ctaaataacc cagttcttca
     6241 agaaaagcaa gggggcgttt gccgtatcgt ttgaggataa ttcctgactc ctccttggtc
     6301 tccgccacat ggacatggag cggaatattt agctcttttg ccatttccaa actcgcttcc
     6361 agcaagtctc tactgcagct atacggagaa tgaggtgcta ccataacctt gaaatttgga
     6421 tttttatatt ttaagatttc gtctatgatg gatcgagttc tgcttatagt ctcagcagtt
     6481 gtttctgtct ctgaagaaaa gagagtcgga gaaaaataac aacgcatctt ggaagttttc
     6541 accacctgat aaatttgctg aatatccaca ccattgggat tatacatatc gttaaaggtt
     6601 gttgttcctg actggagcat ctctgtcagg gcttctttga ccgcattggt agtcatgtcg
     6661 ggagtaaact cagattctgc tggccagata tagtcattga gccattcatg gagattgctg
     6721 tcatctcgga tccctctcag acctgtcatt gcagaatggg tgtgacaatt gaccaaacca
     6781 ggcataatcc aagctccctg atagtctaca atctgctcag cttgttctaa aaacgctggc
     6841 ttatcttgac cgacatagac gatttgagaa tccttgactg ctaagattcc atcaagataa
     6901 acatggaaat tttgatcaca agtcacgata tttacatgct gaaagacttt cattataggc
     6961 tccttttcta aaagacaagt tgtactctct tcaaaccact tcagattcac tttgccgtag
     7021 gtgtggttac tgacttcgtc agttctatct gcaacctcaa aacagtgttt tgaactgact
     7081 tcgtcagtct tatctacaac ctcaaagctg tgctttgagc aacctacggc tagcttccta
     7141 gtttgctctt tgattttcat tgagtattac agtgaacaat ttttctagct attgtaacaa
     7201 aaaagtcact cgaaggcaac ttttttcgtc cataaacttt caaaagagaa tggcttattc
     7261 agaactaaaa gccgcagctt tttgcatttg gtaatactta ccctttctat ccatgagttc
     7321 ttgatggtta ccatattcaa caatatcacc atctactaag acaagaatta aatccgcatc
     7381 ctgaatggtt gacaaacggt gagcaatgat gaagcttgtg cggcccttca tgagttttgc
     7441 aaaggcatcc tgtaccagca cttctgtccg tgtatcaatg gaagaagttg cctcgtctaa
     7501 gataagaatc tttggaatag ccagaaagac tcgggctatg gtcaagagct gagcttggcc
     7561 gacagagaga gattctccag cattttccaa cttggtatcg tatccctgtg gcaactgttg
     7621 aatgaaaaag tctgcattag ctgctttggc agcagcaatt acttgctctc gactggcttc
     7681 aggattgcca aaggcaatat tatcatgaat gatcccttgt gtgagccagg tttcttgaag
     7741 caccatacca aactgctgtc tcaatgatac tcgtgtataa tcataaatgg attgcccatc
     7801 cagcaagata tctcccgagc taatgggata aaaacgcata aggagattga taagagttga
     7861 ttttccagca cctgtcggac caacgatggc taccttacta ccagctggaa tatcgataga
     7921 caagtcctta atcaaaattt tttcaggatg gtagccaaaa gagacatgtt taaaggaaat
     7981 agctccctta acttggtcac tggtcaagac ttccttacct gtttcagcca cttcagggct
     8041 atctaagact ccatagatac gctctacgca agccagagca ctttgcaact cagctagcac
     8101 tgaagaaata tcgttaaagg gcttggtgta ttgctgaaca tagttcaaaa aagtcactaa
     8161 acgaccgaca gtcaaggttg aacccatcat gatacgataa gctcctactc cagctaaaag
     8221 ggcataaatg agtgcattta caaagcgagt cgaaggattg accgttgaag aataaaagat
     8281 ggctgactga gaatagcctg agtagttgtc atgagcctca cgcaatcttt ggataaattc
     8341 tgtttgagca ttgaaggact ggattatagt ctgctggcta agcgattctt caatcaactg
     8401 agtctgaatt cccctcgtct ctgtttgctt ctggaagaga tgataggatc tcttggcaat
     8461 aaagcgtgaa atcaccatgg acagtggcgt caacagcaag actaagagag tcatgaggag
     8521 atgaatttgg agcatggcta gaatactaac caaaatcatc aaaacaccaa tgaaaaattg
     8581 gttaaaaatc atggtcaagc cagctgccaa ctgttcgata tccgtggtta cacgactgac
     8641 catctctcca ttgccttgcc gatccgcaaa agcaatcggt aaccgatgga gtttatggat
     8701 gattcgctct cgtaaatctc tggtataaga gaagattaga cgattataga ggagaggatt
     8761 ggcccattgt accagagtat ttcctattac taccaagagc atctggagaa aaatctgcca
     8821 aaaaactggt gatgaaccag ccactaggac ttggtcaatg acctgcccaa tcagaatagg
     8881 taggtaaatt gataagccaa cttgggcaat agttcctaga aaggctagga aaaggaggaa
     8941 gggatggttt gccaaatcta cgactaaacg tttgagcgtc tggtttacag tttgtcgttt
     9001 cattctagtc ctcctttcca tgttgggatg cattgatttc acgatagact tgactggatt
     9061 tcatcaagtc atcgtgcttg ccaacagcta gcaactcacc tttttccaag aggagaatct
     9121 ggtccgccat ctgtaaagtc gaggttcgtt gagagatcaa aattaagctc atgtttggaa
     9181 aattttctct aatagctttc aagagcttgg actctgtaat ggtgtccagt gctgaggtcg
     9241 catcatctag gatgagaaac ggagcctggc gcaagactgc tcgtgcgata gacagccttt
     9301 gtttttgtcc acctgagaaa tttcgccctc ctgcttcaac tagagcatcc aagagtcctt
     9361 ccttatcact gacaaaatcc ttagcttgag caatttccaa ggcttgccag agttcttgat
     9421 cagtcacttc ttgatttaaa cctaaagtca agttggaacg aatagttccc ttaaagagtt
     9481 cgaccttttg aggtacatag gcaatccaag accgccactg ctccaaatta agaggactac
     9541 gtccattttg ataaaggtca atgttcccct tgtctactgg ataaagtcca agtaagagtt
     9601 gcaccaagct tgatttacca gaaccagttc ccccgatgat acctagaatt tgtccttgag
     9661 tcatatcaaa ggaaatgtat ctcagagaag gctgggccgc atcaggatag gtaaaggtca
     9721 attcttggac ttgtaaaacc ttatctctgg tagcttgctt ttgttctaac tctgaatgga
     9781 tatcctctgg agcctcaaca aagacttcct cgattcgctt ggctgagata taggactggt
     9841 tgagagaatt tatcaacatg gctagcttga ccaattccac caaaatctgt aagaggtaat
     9901 tgataagagc aatgagagca ccttgactga gcactcctcc ttgaattgaa atatagcctt
     9961 gccagataat aacgagaaga gttccattga caatcagata ggtcagaggt gttaataaac
    10021 tagaccagaa acctgtcttt tcttgtaatc tagcataaac ttggttaagg gtttgaaaaa
    10081 tctgtaactc tcgtttttct tgaccaaaag cacgaataac ccgcatccct tgcaattgct
    10141 ggcgcgtttc ctgaaccagt tggtccgttt tctttctgag actactgtag agaggattga
    10201 ccaatcgaga taaccctaca atgacaatgg tcaaaatggc aaccatgact aagaaccaga
    10261 aagtcaactc agttgagatt cgataagcca taaaaatggc accaaaaacg ataatgggcg
    10321 ctcgcaaaaa gagacgcagg aattgattga taccagtctg aatctggtaa gtatccgaag
    10381 tcaagcgagt gaccaaacta gatgttgtca gacggtctct gctgtccttg ggcaaggaaa
    10441 gaatatgacg ataaagatcg tttgtcaatt ccttagcaaa acctactgct gcctttgctg
    10501 agtaaaattg agctatcaag gccactaaaa cgccaattac tgcaaagata aggagcaggc
    10561 caatctgcat ccagagatga ccttgatctc cctgaggtaa agattggtca acaatcccag
    10621 caatcaccat gggaaccaag agctcaaaaa cagcttctaa cagcttgaac aagggggcta
    10681 aaattgattc cttgatgtag ggtttgaagt aagataatag gtgtttcata aatcccttct
    10741 attcatattc tagaaatgaa gaaagtggga agccccactc tctgttttat ttgtttaagt
    10801 aaggcaatag atagccatat cctgcttttt ccatctcatc cttggccaca aagcgtaaag
    10861 aagcagaatt gatacagtaa cggaggccgc ctaactcccg cggtccatct gtgaaaacat
    10921 gacccaagtg agcactgcct gaacgagaac gaacttcaat tcgctccatt ccatggctca
    10981 gatccttgta ataatgaatc aactctttgg aaatcggacg gctaaaactt ggccaaccac
    11041 aacctgaagc aaacttatcc ttggcaaaaa agagtggctc acctgtcgta atatctacat
    11101 aaatcccctc ttcaaaggtt tggtcatagg cattggtaaa tggagcctct gtagcagctt
    11161 cttgtgtgac acgataagac tcttcagata gactggcctt caacacctct tgactaggct
    11221 tttcatagtt tgctgcatca atcaatggct tatcagcatc ggtcacatcg atatgacagt
    11281 aacctgaagg attcttcctg agatagtctt ggtggtagtc ttcagccaga atgtagtggc
    11341 gtaattgctc cacttctact gcaatctttc gacccagcat gcgttcctgc tcctgtacca
    11401 ctgtgtagat agctggcaaa tctgcttcat cctgataata aatcccagtt cgatattggc
    11461 gaccacggtc attcccttgt tgattgatag atagaggatc gataactcgg aaataataaa
    11521 gtaaaatctc tctgagtgac acttccttct catcgtaaat cacttggacc gtttctgcat
    11581 ggtctgtttc cttgatcaac tggtaattgg tcgtttcgac ttgaccatta gcgtagccaa
    11641 cactggtttc tagcactcca gaaatgcgtg aaaaatattc ctctaggccc caaaaacaac
    11701 cacctgctag ataaatttct gccatcttta tttctccttt atcacgtttt taactaatac
    11761 tcttcgaaaa tctcttcaaa ccacgtcagc gtcaccttac cgtatatatg ttactgactt
    11821 cgtcagttct atctgcaacc tcaaaacagt gtcttgagct gacttcgtca gttctatcca
    11881 caacctcaaa acactgtttt gagcagcctg cggctagctt cctagtttgc tctttgattt
    11941 tcattgagta taaacttctt ttcacaaaaa ggatatgaaa ccctctggtc aagagtttcc
    12001 ccatcctatc ttctattctt tattttgctt ctacacggac accttgggta tcaactctca
    12061 agtcatgcag ttttcctttg aaaggttgct tttccaattc tgccttaatt gttggcatct
    12121 tgtcatgaga agccagaacc ataactgtcg gcccagcacc agaaaggtag gttgcatagg
    12181 ccccattttc tttggtcact tgcttaatca tcgcaaattc tcttaccaag tcctgacgat
    12241 agcgctcatg gaagaggtct ccctcgattg cttgcccagc ggtcaccatg tctcctgcca
    12301 acaaggcagc aaccgctaca ttggcgatag aacttgcagc aacagcttcc ttataagaca
    12361 attttttagg caagacacta cggctgtctc gagtacgtaa ttcatagttt ggaatgtaag
    12421 ctagaaaatc acactctgga aagtctgcta cgatagcaga gacttgccct tcaacagaac
    12481 ttgcaataac gagattacca taaatggctg gagccacatt gtcaggatgc ccttcaatct
    12541 tggtcgctaa ctgcaatttt tcatggtctg ataagttgag ttgacccagt tggttggcta
    12601 gttcaatccc agcaacgata accgagctgg aagaacccaa accgcgcgcc aaagggacat
    12661 cactggtcat tttcaagcgt cttggttgca agtctggtac aatttgcaaa gcgattttga
    12721 gcaagagatt acgctcatca tgtggaatcc atttgccaat ctggtgttca atcagccact
    12781 catctcgttc ttcgcagacc tcaatttgaa gatacttggt tacagctaca ccgaccgagt
    12841 caaaacctgg cccgatattg gcactggttg caggtacaat aatcttcatc ttattctcct
    12901 agcaccttga aggtattcaa gaggtcgaat tctgaaacct tcttcaattc agctaagaca
    12961 ttttcaagct gggctttatt aatcttgtgt gtgatgataa cgacacgcgc cttgtcaccc
    13021 tctttgccat cttgaaggat ttgcttaaag gaaatatctt gagcattgaa gatttcagcc
    13081 aacttcaaga cctgaccttt tgagtctaga gccaagattg agaaatagta gtttgctttg
    13141 acatcttcag gatttgccaa gaccaagtca cggctatatt cgttgaagtc tttgccaata
    13201 gtaccatcat tcaaacgacg aacgatacgg acaatatcag ctacaacact tgttgcagtt
    13261 ggtttttgac cagcacctgg tccgtagtac atagactcac caataccgat agattctaca
    13321 aagacagcgt tcattacgcc attcacacta gcaagtgggt gcgctttagg taggaaggtt
    13381 ggagtcactt ctgcagcaat acctgaagaa gtttcctcaa tagaaccaac caatttcact
    13441 acgtaaccaa gctcttgagc tacagctacg tcttctggtg tgatattgcg gattcccttg
    13501 tgggctacat catcaaaggc aatcttcatg ccaaaggcaa attggctcaa aataaccatc
    13561 ttgtaggctg catcaatccc atctacgtca ttcgtcggat cgctttctgc aaatcctaga
    13621 cgttgtgctt ccgcaagagc atcatcgtaa gaccagcctt cttccaccat cttggtcacc
    13681 atgaagttgg aagttccgtt gactactcca agcacgcgcg taattttatc agaagccaag
    13741 gaatttgcta aagtacgaag aattggaatc ccaccagcaa ctgctgcttc gtagtaaagt
    13801 gctaccttgt tagcttgagc gatttctagc aattctgcgc catggacagc taaaaggtcc
    13861 ttgttagcag taacaacgtg ttttccagct tccaaggcac gagtgataaa ggttttagca
    13921 ggctcaatac gccccatcaa ttccactacg atagtaatat cctggtctga taaaatatca
    13981 tccacattgg ttacaaagtt aaagtcattc cctgctgcaa gcaagcgatt tttttcatct
    14041 tcatccttga ccaatacctt agcaactttg atatctgaat gtgctgattg attgattttt
    14101 cctccatttt cctttaggag gaaaggcaca ccacttgcaa cggtaccaaa tcctagtaaa
    14161 gcaattttaa ctgtcatctt tatctcctcg aaattttcta atatagccat tataacagaa
    14221 ttttgtgaaa attcctatta tagtaaatca ctatttcagt ataaaaagaa aaaacgaatc
    14281 agacgattcg ctcttcttaa aatctgaaaa tagctttcca gaaaggatta gccgattttt
    14341 tgcagattga gcactgcatc gtgactcatc aagacttgac catactcttg taagactgag
    14401 cgactgatat cactatcgtc tgcaaactcg cgcatacggg ccaacagcca agctggatat
    14461 gggcttggat gattttcaat atccactaaa atggtcaaat aatagcgctc gttcattttg
    14521 tagagttcag aagtttccat ttcaaaagtc actgtcttgg caaaaactac caagtcagcc
    14581 aacttagcaa aagaaaggat gtagtagatg taaggttctt tcttactctc agcttcttgt
    14641 tcagcctgct cttgctcttc ttccttggct tcaacttgct caagagattg aatggcttcg
    14701 atatcatcct tggttttgtc tgcgatgctt ttttccaggg ttttgataaa ttcatctgga
    14761 gacatttgag ccaattcttc catatctggc aaatccgata agtcttcaaa atctagattt
    14821 tggtcaatct ttgacttggt cacaaagaca tctaccttat caggttttgg agtcacacgg
    14881 aagctcaaca tgcctgtatc cagaaagcta tcaggcatct ctagctcatc caagatagca
    14941 taaaagaact cttctgtttt ttcttgagga acgagaaagt cagcaatctc cattccacga
    15001 tccatcaaat cctctaaaga catcgtgatt tttaaagttg tatcactaat ttgtttcatt
    15061 ttcattgcta gtaacctcat actttcagtt ctatctatta tactagattt ttacgatttt
    15121 atcaaaagaa ggctcctcta tacggataga ttttccctag ggtctttcta taggagactc
    15181 caaaagaaaa tttctgcaga cagatagaaa aagccttcaa aatcagctct tagccgattt
    15241 tgaagacctt atacatcaga atacttataa tttaaaggtt gctacaccaa ggatagaacg
    15301 atttaagttt ctgagaattt gaagactttg ctcaaatttc ttataacgag tcactccgta
    15361 ctcttcaaca agaaggactg tatctctttc caaaagagat gatacatcct gtaaatctac
    15421 aaaatgcatt ccttttaaag cttcttgact ctgtttcaat ttatctagga tagctttatt
    15481 tgagctaacg atggtcaatt cctgtccagt atttttgtat gacaaaacat ctgctaggtt
    15541 agcaattgtt gtaatctctg ttacaaaatc aatttgatac tgagaaaaat cacctactct
    15601 attgattgtt ggattaaaga gataaactaa cacatttccc atcacaacca aaatcacaca
    15661 aaccactcca ataacaacta aacgaagaat cagatttttc acatttaagc caagcgctgt
    15721 ttcaccattt gcgttcaatt ctttagagtt gatggtttcc agtttttcaa ttttcacatt
    15781 tgcataggca tgtttaaatt tctcaatcaa cccatcaatt tttttctcta acaagtcatt
    15841 ggcatcttta cttgatgtca aaattttcac accaacccct gcatcgtcaa tcatatagta
    15901 gacggtcaat tttttccacc aatagtcatt cgttgaattt ttcaaggttg tttctgtcgt
    15961 gtctaattca ctggcaattt ttttcaactc actgggttct acatcattga aaagataagc
    16021 tccattcaaa ttaccatcaa tcaatttccc ataaaaatca ctataaccac caatttgatg
    16081 attcaaaatc gttttggccg actcttctgg aggagtgatt ttatagataa gataagttga
    16141 ataacttgtt gtatctttga cagtgttttt attcctaact gctttaattg taaatggtac
    16201 agcaatgaga gcaaataaag cgatgagagc taaaatattt gcttttcgct ttttataaag
    16261 atttgcaaac aaatcagcta ctgaataatg ttcaaacatg atttttttct cctttgttta
    16321 gtagatacta gttttccttt gtaagcattt ttgctacaaa tataatcaca agaacaattc
    16381 cccagaattg cattgtaaat aaattgaaga aactttctga aaagctgctt cttggcataa
    16441 agaatagatt attcaagatg agtagggata aagcaaatag gattgtcctt gagcgatagg
    16501 ctacttgcag catggctata aataatacgc cgagtaagaa actaagcaga aagactccaa
    16561 tcataccata gtcggtatac aactccatga tataactact tccgatacca tgccctttca
    16621 agtattcctt gttcaagaca agataggata gattgtgggc ataactatta ctatcaatag
    16681 ctagttccac actattggtt gtatgttcaa aggcttttcc tccgaaaatg gctcccaaac
    16741 tcccccttgc aaaataatca agaacaggac caaaagtaaa attacggaaa tctcggtaag
    16801 ggaggctact gttaaataga aaacctcgag ccagaacacc aaaactagtc ccttgtttat
    16861 agataaagtc aagtaagata tcccagaaac ctgtatggga aacttggaca ttatcccgta
    16921 cataattgag tactcccatc gctaacatga gaataggaga acctacaaaa atcgctaact
    16981 tttctttaaa cccaatccat tttccttttt cagcttgctc ccgcataaag taataaacaa
    17041 aagcaaataa aatacttaaa ataaagggat ttcgtgtccc aattgccaaa tgaatagtgt
    17101 tagctgcaat aaaggagaca agcactgctg tggcctgcaa tttctttggc ttggttgcca
    17161 gatacataca cattgcatag accgtaaagg tagacaaaat gtaggtaaaa taaggcagtt
    17221 tactttcaaa atttgcatag taggcatagt aggaagtctg caaacgatac aagagccgtt
    17281 caaataaccg aatgaaatag aaaggataag ttagaagaaa aactcctagt gatacaaagc
    17341 gtaaccgctt gatataaacc tcttttagag aatttcctat atttgctact tttattttct
    17401 tcctagctat gaagtaacga gccaggacgc ctcctgttgt caagcccaga atcgaaacca
    17461 tgacaactat aaaggcaaaa cgataggcta ttggatgata ggtatccaaa gcaccatccc
    17521 taaaataatc aatggtcggt cttgatacca gaaatacaaa aatggttaaa tagaaaataa
    17581 aatggattaa gtaatacttg atatcattcc aacaagcaat caagctacta accaacaaga
    17641 acaataaagt agaaagtaag ctaacattat tattattaaa cagatacaca attccactta
    17701 ctagcgtcaa ggcataactg actatggtca aactaaataa taatcgtttc ccatcaatca
    17761 cttggtcacc cccgttctaa tgtaattttt tagatttttc aatatttttc agtaataaga
    17821 atcggtataa ggaaatattt atgaataggg ccaaagcact aattcttctc cccttacgga
    17881 aaattggatt cctagaaata gcaaaggcat ggccttttaa aaaacgatga atctgagaat
    17941 aggcttcaaa ctgtttatac tgatcatcta gcaacatctt atccagaata aagaagtggg
    18001 cataggccaa tctgaaaaaa gcgacctctt tcaagtcagg atagtttttc acaacttcat
    18061 tataaaactt ttggtagata tcaatatagg ctaaatcctt ctctgcatag ggtttggtcg
    18121 taatactatc ccctctatgg aaatagtaat aatagggttt agtattaacc acatacttct
    18181 tggccaactt gattaaatca aaatggtaat aggcatcttc gtaaatcaac cccttaggaa
    18241 aggataggtc agttgcaatc tgtctcttga ttagcttatt gcaaatcgtc ccaggtattt
    18301 tttcacctat gaggtattcc tttagaaatg tttgagaatc acagacaaaa tagtcatcct
    18361 gattggctga ctgtgggctt tcatcattag catagacatt catgacacca cagctcgaaa
    18421 catccgcatc ttcttgaact aattgctcat ataagctctg aatcatttct ggatggatat
    18481 aatcatctga gtcaataaaa atcagataat ccccgtgagc ctgcttcatc ccatcatttc
    18541 gtgcttgcga caatccttcg ttctttttat gaagcactga caccctgtca tcttgttcag
    18601 cgattgaatc acacaagcga ccactttcat ctgttgcacc atcatcaaca agaataattt
    18661 ccagattttg ataggtctgc ttctgaatgg aagctatcga tttttctagg tactgcgcca
    18721 cattatagac tggcacaatc acactaatta atgcagtttc catgctactc ctctaatagt
    18781 ttttctactt gttcgatttg ttttgtaatt gtaaattgtt gaatgaattg gctagcctca
    18841 tcgacatcaa agtttgaggc agaagtcatg taattagtaa tcgcctgagc tgcctcttga
    18901 ttgctctcaa tgatttgtcc aaatcgtcct tcttgggata attcctcagc ccctccaacg
    18961 tccgtagaga taaaagggag tcccagactc aaggcctcca catacactcc aggaaaacct
    19021 tcttgtttag acatagacaa gagaactttc gtctgagata aatactgata aggatttttt
    19081 tgataaccaa ggaaatgtac atagtcctca atctcatact ctttgactcg ttttttcagt
    19141 tcctcttcca tatcaccagc cccgataaaa tagagatgat agttttttcc ctcttggtgt
    19201 aataatcgta tcacttccac tacacggtca gaacccttat tttcctcaat ccgtccgata
    19261 gtacagatac tttgaggagc aatctcgata tcgatcttct cttgagattt ttctagaata
    19321 gtctgaaaat catatccatt gtagattgtc tgtaatttag aagcataatc tggataaact
    19381 tccttgatag aattgctggt cttttttgaa atccctacaa ttgtattcgc agcatccaac
    19441 tggcttctat gtgattctct tttagagcta tccttaagaa gttcttcaat acttccatga
    19501 atccaagata tcttcttgac ttctcttctt ttagagaaca acagtggtgg attcataatg
    19561 gtaaaagaaa cttcaacatc ataatcatct tttacaagca aacgacgagt cagtcttgga
    19621 aaataaattc tcattctcca caaaaaagct cgtaaccatc tggtttggcg ataatcttga
    19681 agggatttta aaatgcgtac attctttgga acagattcat atcccttgtc aaagtgctcc
    19741 atttcaagaa tatcaatatc atacttttct ggatccagat ttgaaacaat ggttgataga
    19801 atcttctctg caccacctcc aagagaaaaa gaccacataa aaaataagat ttttttctta
    19861 gccaccatat tctcccttgt attctgtata agacttatcc atatcagcga tgacagcatc
    19921 atgatgcggt acctgcttgt ctgctggtgg aggcgtcata taatccccaa aagcagttct
    19981 gagatagaca tcatagccga ttggaatagg catctctgtt ccttcaaatg gcaagaaaag
    20041 attgtcttca aaagatgtga ttgggtactt gtttctcatg tagccaggac ctgagcataa
    20101 ttctgtaatg ccatcacaat cagccaaatc atacttagtc atttctttct cagctttttt
    20161 ccagatgcga taacggagag attttggagt caaacccagt aaaatgcgac ttccccattt
    20221 catgagagca ccatgctttt ctggaatagt ttgcgcacaa aagagtgaat aaatcaaggc
    20281 ccaacgaacc tgttttttcc gctcagctgg atttttcgga taataatcca aaggcaaaac
    20341 atccaaggcc agaccatgtg gcaaatccaa atcctgctga taaggcttga tacaggtggt
    20401 ttccttgtca cgaatggtaa taaaaagatt acgatcaaca aaattcttgt gactctttga
    20461 caagaaataa cgttcatctg cataacgagg ccataattct gctaatttct cataatcttt
    20521 acgaggcata aaaaagtcta ggtcgtcgtc ccaaggaata aatcccttgt ttcgaagggc
    20581 accaatagcg cctccgccac agagataaca gagcaaatca tgttctttac aaaaggccac
    20641 aaaatattca gccatctcca gactacgagc ctgaattgct tttaaatcag tcatattgtt
    20701 cattattctt tctatcgtat cgtttcatta taccacaaac aaggggtgaa aatctattgc
    20761 agactgtaaa aaatcaaagc ctgactgcta tccaaatagc tatcaaactt tgatttttct
    20821 gtcttatact cttcgaaaat ctcttcaaag cacgtcagct ttaccttgcc gtaggtatag
    20881 gtaactgact tcgtcagtct tatctataac ctcaaaactg tgtttttagc agcctgcggc
    20941 tagcttccta gtttgcactt tgattttcat tgagtattat cttatctcaa gcccatttga
    21001 gcgagcttgg tttgatattt gttttgatca accagcaagc ccaagcctcc ataaacatca
    21061 taggcatcta cccagtcacc cagttctgga atcgtcaatt tttcaatacc attttttgct
    21121 ccatccaaaa cagataaacc gtttgttagg aggaaagtat agggtacgtt ggttgaggtc
    21181 atagcaaaaa cctttccaag agcttcagaa ccagtgaaaa gtttagtggg atctttaatt
    21241 tgctctaaaa ttgctgttaa aacttgttgc tgtctttttg tacggccgta atccgcctca
    21301 tcatcatcac ggaaacgagc ataattgagc agggtcgagc cattcatctg ctgttttccg
    21361 actttaatgg tttgggttgg agactcagtc tcggtagcat ataaatcatc tccgactgta
    21421 gcttctgtta ggggacgccc attcaatgtt gaaaattgag catcaatcgt caccccatca
    21481 gggaaaagcg tgtcaatcgc tgtggcaaag gcctggaaat caaccaaggc gtagtactta
    21541 atgtccaagt caaaattatc tttcaagact tggcgaacca tttctgcccc tttttgcccc
    21601 tcttgttctc ctaactcgta ggctacgttt aacttgttat ctgtctgttt tctaccatta
    21661 atcacttgac tataaccatc tatatagacc aaattatcac gcatgaaact gactagcttc
    21721 attttcttat ctgagccccc gacatttaat accataatag agtcagttcg tgtctcaaca
    21781 ctgttctggc cgattcgacc atcagtaccc atgattaaaa tattaactcc atctctagtg
    21841 tcctgaccat taaagacttc tacttgagct gcccgggcat cagcagtttt ctttgcgcta
    21901 gcatcttggt aaccacgcaa aaacatgaat accatggcca aagccacaca gaccaaaagt
    21961 gaaaaaatca ccataaaaat tcgtttaaga cggagcttcc gtcttttctt ttttggaggg
    22021 aaagagagtg cttgtgattt ggattgtgag cgactccggt tcgcatagct tggtaagtca
    22081 acctgctctt ctctttcttg ttccaagcta gagctactat ttcccctagc aagagttagc
    22141 ttttcttgca aataggcaaa ctcatttttt tctctctcat tgagatagtg aatatttttt
    22201 agcaaataat cataacgcaa ctgctcatga tgacttaagg gattttcttt actcatcttc
    22261 tctcctttcc atggtctgat attggataaa taggataggc acccagaatt ttatactgga
    22321 ttccaatcgc ttctaattct ttttgggcaa agtggaccaa gtccttatcg gtataatcca
    22381 catcgataat gaaaaagtat tcacccagtg ctgtcttgag tggacgactt tcaatttttg
    22441 tcaagtcaat tcctcgccaa gcaaaggtcg acagggcctt ataaagtgca cctggaaggt
    22501 tgtcaggtaa tgtcaaggcc aaactcatct tttcagtttg tgcttgcaag ggaatactag
    22561 gcttttcagc tcctagaagc cagaaacgtg tgaaattggc ttccatttcc tgaatatcct
    22621 cggcaatcag ttccaatcca tattcttcag cagaacttct aggtgcaact gctgcaaagg
    22681 gctgatctgg atgttcggaa ataaaacggg ccgcataagc tgtactagct gttacctcga
    22741 tttgagcctc tggatattgt tcatcgatga atttctttcc ttgagccaag gcctgtggat
    22801 gtgaaaaaat cttttcaatc ttagtatggc ctggaaccac catcaactgc tgatgaatag
    22861 gctgaacgat ttctgctact gcttggatgt gagcctgatg aaaaagatag tccaaggttt
    22921 catgaacact accctcaata gaattttcaa ctggcaccac agaatagtcc actaatcctt
    22981 gctcataagc cttgatgaca tctgtaatgt tggcaaaagc ctgcaattcc tcatgaggaa
    23041 aagctatctg cacaacgtgg tgtgaaaatg atcccttggg acctagataa gcaattttca
    23101 tcttagttcc tctataattt cctctgggct tagcttggtc acatccaaaa cccgactagc
    23161 cacttcctca taccaagcct gtctttcttg aaaaatagct actagttctt ccttgctatt
    23221 atttagaaaa agcggtcgct gattgtcctt atcagctgcg atacgttggt agagggtttc
    23281 aaaatctgct ttcaggtaga tgttatctgt attagtcttg agtaagtcac gatttctctg
    23341 agaaataacc actcctcctc cagttgacac gacttggtct gtttgtagta aatcagctag
    23401 gacttctgat tctacctgac gaaaggctgc ttctcccttt tcagcgaaaa aattcgcaat
    23461 ggacatacct aggcgcttct caatcagagc atccatatca aggtaattag ggttcaagcc
    23521 tcttgcaata gtcgattttc cagcccccat aaaccctaat aacaccttag ccatgaatca
    23581 agctctccaa atcatcaaag aaactaggat agctggtatt gatggcttct gcacggtcaa
    23641 gctccacctc tccatctgca accaagaggg ctgcgatagc tgtcatcatg ccgatacggt
    23701 ggtcaccaaa cgtattgact ctagcaccgt gaagagctga tttccctttg ataatcatcc
    23761 catctgccgt aggagtaata tctgctccca tactatttaa ggcgtctgcc acaacctgaa
    23821 tacggtctgt ttccttgacc ttgagctcct cagcatcctt gataactgtt acaccttggg
    23881 cttgagtcgc aagcagggca ataatgggca attcatcaat caatcgtgga atcaaagcgc
    23941 caccaatctc tgttcctttc aagtcagaag actcaacagt caaggtagaa gatttagcga
    24001 ctggatcgat ttcagttatt tccaattttc cacccatggc acgaatgaca tcaataatac
    24061 cggtgcgagt ttcgttgatc cccacattct gcagcactag acgagaattt ggaacaatca
    24121 aacctgcgac taaccaaaag gctgcactgg aaatatctcc tggtacgacc accttctgtc
    24181 ctgtcaattt ttgtggccct tggactgtga ttttcttacc gtccacactt aaatgaccac
    24241 caaattgttt caacatatct tcagtatgat tacgggtgca ctctttttcg ataataactg
    24301 actccccctt agcttgtaag gctgcaaaca tcaaggctga cttgacttgg gcagaggcaa
    24361 ttggcaactc ataatgaata ggtcttaggt ttttcgtccc ttttaagcga aggggaggca
    24421 agtctcgttc agtttgccct gaaatgctga cgcccatttt tttcagtgga agggtcacac
    24481 ggtccatagg acgtttggaa agactatcat ctccaaacat ctctacttcg aaatctgcac
    24541 cagcaaggac acctgaaatc aggcgaatcg aggtgccaga atttcccata ttaagggcat
    24601 tttgtggcgc ttttaagcca gccatgccta caccttgaat ggtaataacc ccatctttat
    24661 cctcaatttc aacaccaagg tcacgaaaaa cctgcatggt cgaaagaacg tcttcacctc
    24721 gcagaatatc ataaaccttg gtctcaccct cagccaaact tccaaagata atggaacggt
    24781 ggctgataga cttgtcacct gggacgcgga tactaccatg taaatggcga atgtttgttt
    24841 ttagtttcat actggacctc atacttgcaa tacttttacc tattttatca taaaaagcca
    24901 gaaattcctt aaaaattcct gactttagga tagttctttt cttatttcag caattctgaa
    24961 actggttcaa aaacaatttt ttcaatgtca gaaaggtaaa tggccaattg ttgttgcttg
    25021 gtaaagaatt ctgacaagag gctatttcct tgaatctgtt taccaaagcc ttccatctta
    25081 gcttggaagg acgcatctgg catttgacct gtatgtgcta gtttttgaat ttcctcttga
    25141 aaggcaagat attctgtaaa gattttgctt gcctcagcat ctgctgcaat cgcatcttta
    25201 gctgctttaa cagccttgta ttctggtaat ccgcgtagac cgcgactgag ttcgtttgca
    25261 ctatcgtaaa tatttgacat gttcttctcc ttatttgatg acgactgtat agtcggtatt
    25321 ttctgttatg agatgctcag ctctttccaa gtcttgagca tttttaaatg aaatttgtag
    25381 gattccgtga atatcctcac gattttcctc gttgatgtgg atgttaacca aggaagttcc
    25441 acgtagcagt tccaaaatcc gcaggatgac atcttcttca tcaggaacgt caacatagag
    25501 gtcgtaagag ctatccacac caccacgctt atggatttcc atggtctggc gttgttcacg
    25561 cgcttggtta aaaaagttcc aaatttgctc ttcatctccc ttactaatgg cctgaccaat
    25621 cacttccaaa cgttccttga aatcctcaat tctatccaga atggtctcgc tattggacaa
    25681 gagaatggag gtccacattc ctggctcgct ttccgcaatt cgggtcatat ctcgaaaacc
    25741 acctgccgca aagcgccttg ccatctcatg ctcttgagca tagaccgcag tctgctccat
    25801 gagactagaa gccaaaatat gaggaaaatg gctaatctga gaagtgacac gatcatgctc
    25861 cttggcatca atctcgataa aacgagcatg aagacctgaa agcagatcct tcatttcctt
    25921 aagcgtgtcc tgacttgtca ggcttgaagg tgtaaagata taataggcat tttcaaaaag
    25981 attgacatct gccgaagcag cccctgtctt gtgactacca gccatgggat gggccccgac
    26041 aaagcgaaca gacttgccag ccaaatactg ctccgccgca tccacaatgg ttgacttggt
    26101 cgaaccagca tctgaaataa taacgccttc tcgcaaatcc aaattggcca actccttaat
    26161 gaaagcaata gtttgtttga ttggcaagct gaggataatg acatctgcca aaggagcaaa
    26221 actagcaaaa tcatccgttg cacggtcaat catgccttct ttcaaggcga tatctctcga
    26281 agcttgacta cgattataac ctaaaatttc ataatctgga tgatcgcgtt tgataccaag
    26341 tgccatagag gctccaatca acccaagacc tgcgatatag attgtttttg ccataggaac
    26401 tccttaatag ttctttgtat agtctcggtg tttggctacc gcttctttta gttcctcaag
    26461 attatctgat gagaattttt cgaggatttc ttgcgccaga accgttgcta caactgcttc
    26521 catgaccatt cctgcagctg gaagagcagt cggatcactt ctctccacgg ttgccttgta
    26581 aggttcgtgg gtttcgatat ccacactcat aagaggttta taaagagtag gaatgggttt
    26641 catgacccca cgaacaacga tgggttgccc attagtcata ccaccttcaa aaccacctag
    26701 attattggta cggcgagtat aaccgtcttc tttagaccag agaatttcat ccataacttg
    26761 gctgccttta cgataaccag cctcaaagcc aagaccaaat tccacccctt taaaggcatt
    26821 gatagagaca acagcttgag ccaatcttgc atccaatttt ctatcccatt ggacatagga
    26881 accaagacca actggaacgc ctccgacgac tgtctccaca accccaccga tggtatcacc
    26941 atcacgtttg atttggtcaa tatagtcctt gatttcctgt tctcgttctt ggttaacaat
    27001 agaaacttca gactgggcag ctctttgctt aatttcagcg actgtcagat tttcaggaac
    27061 atcgatttcc ttgccaccaa agaccacgac atggttggca atctccatat ccagctcagc
    27121 caagaggcgt ttggctactg caccaactgc cacccgcatg gtggtttcac gagctgatga
    27181 acgctccaaa gaatttcgca aatcatcaaa acggtactta atccccccaa ccaaatcggc
    27241 atgacctggg cgaggatgag taattttccg cttgctttta aggcggtctt caatgtcctc
    27301 cgcagacatg atgtccagcc atttctggtg gtccttattg atgacatcca tagtaatagg
    27361 cgcccctgtc gtcttcccgt ggcgaacgcc cgaagtaaag acaacctggt cactctcaat
    27421 cttcatacga ccaccacgac cgtagccacc ctgacggcgt ctaaggtcct cattgatatc
    27481 ctcagctgtc aatggaagtc cagctggaat tccctcaata atagctgtta gacgggggcc
    27541 gtgtgattct cctgcagtta aatatctcat acactctcct tattttacca agtagtcttt
    27601 catctcttcc agagaaactg ggtgaatgat cgctgaacca agctctggca ccaagaccaa
    27661 tttcaaggtg ttaccacgcg ctttcttgtc atgagtaaga gcctgataaa gcttgtcaac
    27721 ttcccaattt tcatagtcaa caggcaagcc gaatttctga cacatctctg tgatagattg
    27781 ggtaatgcca gctggcatga ggcctttttc ctcagcaacc ttggaaatct gtaccattcc
    27841 catggcaaca gcctctccat gcatgacctt gccataaccg gcagtcgctt cgatggcatg
    27901 gccaatagtg tggccaaaat tgaggtaaag acgaatacca ttgtccaact catcttcaac
    27961 caccatcttg cgcttcacct gacaagaatg ttcaatcaag gtctctgcat gttccaaaat
    28021 actctcaaca gaaccattca gtcccgtcaa gagagcccac agttctggat cctcaatcaa
    28081 gccatacttg ataacttcac ccatcccttc aatcaactct ttttttccga gggtttcaag
    28141 aacaagtgga tcaatcagaa ccccatctgg ttgggcaaag gtccccacca tatttttagc
    28201 aaatggtgtg ttaacgcctg tctttccacc gatagaagaa tcaacctgag ctgtcaaact
    28261 agtcggaatc tgaacaaagt gaataccccg catataggta gaggctacaa agccagccag
    28321 gtccccaaca acgccaccac caagagcaac gattccatcg ctacgagtca gaccttgctt
    28381 gactagaaat tcatagactt tctgaacagt agttaaattc tttctttctt caccttctaa
    28441 gaaatcaaaa acagctacct gaaaaccagc atcttctagg ctgagcttga ccttctctgc
    28501 atagagagag gctacatggt tatctgtcac aatgactacc ttttgcggtt gccagagttc
    28561 tcgcaaccac tgaccagcct gggccataca acctttttca atctgaatat cataaggatg
    28621 atgaggaata tcgattctga ttttcatagg agagtctccc tttctttatt ggtatttttc
    28681 tgttaaagac tgccaaatct cttctgtcgg catttccttg cctgtccata gttgaaaagc
    28741 ttctgcagct tgatagagca acattcccag accattgact gctggattgc cctgacttct
    28801 agcccatttc aaaaacggtg tttcaaaggg ttggtatatg atatctgcaa ctaagagagt
    28861 ttctggtaag actatgtttt caggaacagg agagaattgg ccatccatgc ccacactggt
    28921 ggcattaact agcaaatccg actcggcaat ccttgcttgc agttcagaaa catattctaa
    28981 agcacacaaa tccactttaa agcctgtctg ctcctgtaac ttgtctaggt aaggtcttgt
    29041 tttttccata gaaacggaac gaacaaagac cgaaatctga ctgacgccat ccaaaatagc
    29101 ctgtgccaag attgatttag ccgcaccacc tgcacccagc aggatcatct ttttacctga
    29161 aattgtaaaa gaaggcaagc acttaaaaaa tcccttgcca tctgtattat atccaattaa
    29221 attgccattc tcattgacaa ccgtattaac cgcaccaatc aagcgcgctt catcgctcag
    29281 cttatccaaa taaggaatca cctgctcctt atagggcatg gacagattga tgccaaacat
    29341 ctggtagcga cgaatattgg ccactgtttc taccaagtca ctcgcttcaa tctcccaagc
    29401 cacataagca ccgttggtag ctgtcgcctc aaaggctcta ttgtggatga agggagaaat
    29461 agaatgctta ataggattgg caacaactgc agctaaacgt gtatagccat caagcttcat
    29521 ccaaaatctc cctgattttt ttcatgctag ctagagaaat ctgcccaggg gcactaacct
    29581 catccagact ggcaaaagac caactcgaac cagtcacatc cgcagtgata cgagagacct
    29641 tgcccacctt acccatagaa atggtcacat attcctgttc aggattgagg gttttaaagc
    29701 ctcgtgtata gttcatcaag tctaagacat cctgctccgt gtgagccatc accgcaacct
    29761 taacaagttt tggatttaga atcgtcaact ctgacaagat ttccatcatg ttctcaggtg
    29821 tttcttggaa attatggtaa ctcaaaacaa gatttgggaa gtccagcatt tcctcaaaaa
    29881 catccttgta gctatagtac tcaaaatcaa tatagtctgg ttgatagagt tgcgcaactt
    29941 ccttgattag atggatatac tcttctggag aaaggtcgat ttctccacct tcggagcgag
    30001 ttcgtagcgt gaaaaccaac tcacggcctg cgaatttttc aaaaatggct ggagctacct
    30061 gcaaaatcgc ttctttaggc agatagtcgg cacgccattc aatgatgtcg gcatccaggt
    30121 acctcgtggc atccagagcc tgagcctcct ctaaacttct tggcattact gaaacgatta
    30181 atttcattta ctaaccttca tactaatcac cttgaggtaa ttactacttt catctttttt
    30241 attataggca aaatctgctg gaagaccata tttgtttaaa atctggtaac ttcttcctgc
    30301 aaagccttta tcaatttgtt ctgtaaattt ctgacgggaa acattggcag cattggtact
    30361 ggcaatgata atccctcccg gatttaaaat ctcaagactc tgggaaatca acttgtgata
    30421 atccttggcc acagagaaag tttgtttttt attccgagca aagctaggcg gatctaggac
    30481 aatcacatcg taggtcaagt ttttgcgttt ggcatatttg aaatactcaa agacatccat
    30541 gactataaaa cgatgctcgt ctgtgctgag cccatttgcc tgaaaatgcg cttgagacaa
    30601 ttctcgtgaa cgtttggcta gatcaacaga agttgtctgg ctagctcctc ccatggccgc
    30661 agctactgaa aaagccgctg tgtaggaaaa catattgagc aaggatttac ccatagccaa
    30721 gccgtcaact aaactaccgc gaacctcatg ctggtctagg aaaattcctg tcatcaagcc
    30781 atcattcata aagacttgat acaggacacc attttctaaa acagtgaaaa agtcaggtgc
    30841 ttcttgacca taaacatggg cagattcata gtccaaaccc ttaaagcgga ttttctcata
    30901 agcccctaaa acctcaggga aaacctgtct aaaggcttct gatatagtct gacgaatctg
    30961 ataaacataa gagttatacc aagaaaagac ggcgtagtcg ccataaaggt ccactgtcag
    31021 acccccaaag ccatctccct cttgattaaa gagacgaaag gcagttgtca aatcatcttg
    31081 atagtaggcg tttctctttt ctttggcttt tctaaacaac gtttcaaaga aagcttgatt
    31141 gaaggccacc ttgtctttgc tgataaacca gcccaagccc ttgttttgct gagaaaggta
    31201 ggcagtccca agaaagtttc cttcctgacc ctgcacctct acttcccgat ccttaagatt
    31261 gacattctca agatcactgg cttctagtaa aactagcccc ttagcaagct tcttttcaac
    31321 ccttttgctg actcttattc tattcataac taccattata tcaaactttt agacaattct
    31381 caaaaaagaa actacccttg cttttttact cttcttttaa aaaatggtat actagacttc
    31441 ctgcaaaact aggaaataaa tgtgtaagaa tcacaataaa aaatgctctt ccgtcttgga
    31501 ggagcatttc tttttatcaa cgaaaatcaa atagcaaact atgaaactag cctcaggtta
    31561 accgtgagat tataggtaga gaggttgtat cagcaatatg tgtctgtcaa atttagtgac
    31621 aaaggtagta gaagaaagat gaagaaataa atcagcttca gtaggtatct ggaaaatttg
    31681 attttataga gaagcctttt gttacaaact caatatacta tcaataaata atattataga
    31741 agcaacaata attaaaattt cacctatttg catcattcta tttcgaactc taaatatatg
    31801 ttctatcaaa aatacttgga tcacacacat tataggaatt aacgtttttg aaattgaaaa
    31861 atatcccaat aaataaacta taaacaacaa taatagaact atattatatt tcttattcaa
    31921 aacattcctc cctatatttt tgattaccaa tcttaatcat ttacaactac attctaacaa
    31981 actataaaag cgtttgtcga attgaattta tcaagcaagc aaccaactat ctcatctttt
    32041 ttctatttct gccaatatgc gtgacaggta ataatgatag ccaaaaatag caagagcaag
    32101 caagacgata agagctccta ctcccaagtt gatggcaagg ataggggaga gagactgaac
    32161 caagaatatg ctcccaatta caagggccat caggattgca ctataaataa acaataaaac
    32221 tatggcgact atgccatttg aacgattcac caggtccgta atgctactcc aattggttga
    32281 cagattttta acgtccttaa agtaatggtg gcaagaaagg atgacactgg caatgatcca
    32341 gactacaaga aggtaaatca tcgaaaggat ggacaagcct agatatagag aaagaccgag
    32401 caaagtcaga actggtaaaa aggactgaac agcaaagata atccaaaatt tcactttcac
    32461 ataacgagca aagtcaaagg gtaaactctt cagaaaatca acattttccc tctccaagga
    32521 caaggcaatt gaatgcaggc tggtgatatt gttattgaca actgctataa acactcctac
    32581 aaaaaacaag ggtaaccagt atggaggatg aatgtctgga actatctgag aatctcggat
    32641 tttggaaatc agactgatca tcatgagata aggaaggaaa gcacttgtaa aaagcactgt
    32701 aatcacacca gtcccctgtc ccaagagggt gaggtggtag cgtaaaacca tacggaaaaa
    32761 gcccttttta gtagttgaaa tcctctcctt gctgcgacgt tcttttttga ccttctcctc
    32821 actgttaagc aggatcacgt cataaaaacg aggaaggacc ttctttttgg tcagataaag
    32881 caggaagaga gttagtccta tccaagcgag cagacccact aaggcttctg tcgaaaaagg
    32941 ctccactgct attttgtaaa agatatgaag aggataaagg agaaatggaa tgtctctaac
    33001 tttgtcaaca atacttccaa aagtcgactg aagaaagaag ataaatatta aaggtatgag
    33061 aactcctatc ccaatcatca cattcgaaaa aatagactga tactttctga agaccctagt
    33121 ctgagccaag aaatgtactg ccactaccgt cactaaagta acagagacaa ataataaggt
    33181 caaggacagt agcatcaaag gcaaacccag ccaaagagaa ggagctagac taatatagag
    33241 ggctagaaaa taagctagga ttggtacaat tccagttaga gctggcaaga ggacagacag
    33301 acctttggcc attataatct ctgattcttt aaaggcatag ggcctatagg aggccaggtc
    33361 cttactctca taaaagacat tgtaaaaggc agtgaaagaa gttgaaaagg ccagcaccag
    33421 taaaatagca accatcgagc taaaataaat aggcatttcc tcaaaaggaa aatgaatggc
    33481 tatattacta aaacagatga gcatcaagag actggaaaaa atgtaagaac ttaggactct
    33541 agcagaaaca tttacttttt tcccaggatt cttagcctgc ttctttcgta gattagccag
    33601 attagcttct tgagatgaat agaggatatt gatatcaact aattttttaa tgaccttgag
    33661 acgcatccgc aacctcctct tttctaccag caagactaag gtagatactt tccaaaaact
    33721 ggtctgggtg gtctttcctc aagttctcta cactaccaca atagatcaaa tgcccctttt
    33781 tcaaaatagc aatccgatca cagacttgct cggctacctc aaggacatga gttgaaaaca
    33841 agaccgtctt gcctttttgt gcatgttcct tcatcatttg cttcaaatca aaggcggcct
    33901 ggggatccaa accagtcaag ggttcgtcca aaacccaaat atcaggagca gacaagagtg
    33961 ccccaatgac aaagactttc tgacgcattc cgtgagaaag agtttcaata acctgatagc
    34021 ggttttcagc aaaatcaaaa acgttcaata gcctagctag actagtctcc aagtcagagc
    34081 tagtcagatc ataggatgaa gcgatcaatt cccaaaattc attggccgtt aagcgtaaaa
    34141 ataagtcagg cgagtctgct acgtagccaa tctttcgttt gatcgccaag cgattttccg
    34201 ataactcctg accgtctacc aaaatacgac cactgctggg tgaaatgata ctgactaggg
    34261 attttatggt ggtcgatttt ccagccccat tatgaccaat caagcccata atctctccat
    34321 tttcaatctg caaattgaga ttactcaagg cctctttatc accatacaac ttactaacat
    34381 tttgaaattc aatcatggga caactcctat ctttatctgt attatacatc gctatactag
    34441 cactttgata caaaaaaatc aatactttat tttaagtagt taaaatagtt tccttctatc
    34501 ttacgcaaac gtttgcgccg agagatactt tatgatagaa taaagaacaa gattgacaag
    34561 taagaggaaa catcatgcaa aatcaaacac tcatgcaata ctttgaatgg tatctgcccc
    34621 acgacggtca acactggacg cgtctggctg aaaatgctcc acacctagct catctgggga
    34681 tcagtcacgt ctggatgcca ccagccttca aggcaaccaa cgaaaaagat gtcggctata
    34741 gggtctatga cttatttgac ttaggagagt tcaaccaaaa agggactgtc cgcaccaagt
    34801 atggtttcaa agaagactat cttcaagcca ttcaagccct taaagaacag ggaattcaac
    34861 ctatggccga tgtagttctc aaccacaagg ctgctgccga taacagggaa gcctttcagg
    34921 ttatcgaagt tgatcctgta gaccgtacag ttgaacttgg agaacccttc accatcaatg
    34981 gctggactag ttttaccttc gatggtcgcc aagataccta taatggcttc cactggcatt
    35041 ggtaccactt caccggtaca gactacgatg ccaaacgcag taaatctggg atttatctga
    35101 tccaagggga caacaagggc tgggctaacg aggaattggt cgataacgaa aacggaaact
    35161 acgactacct catgtatgcc gacctagact ttaaacatcc tgaagtcatc caaaacatct
    35221 atgactgggc tgattggttc atggaaacga ctggtgtagc tggtttccgt ttggatgccg
    35281 ttaagcatat tgactctttc tttatgcgca acttcatccg cgatatgaag gaaaaatacg
    35341 gtgacgattt ctatgttttt ggtgaatttt ggaacccaga caaggaagcc aatctggact
    35401 atctcgaaaa aacggaagaa cactttgacc ttgtcgatgt tcgtctccac cagaatctct
    35461 ttgaagccag tcaagctggc gcaaactatg accttcgtgg cattttcaca gatagcctgg
    35521 ttgaactcaa gcctgacaag gctgtgactt ttgtcgacaa ccacgatacc caacgaggac
    35581 aagcccttga gtctaccgtt gaagaatggt tcaagccagc agcctatgcc ctcattttgt
    35641 tacgccaaga cggccttcca tgtgtctttt acggagacta ctatgggatt tcaggccagt
    35701 atgctcaaga agatttcaaa gaaatccttg accgcctcct agccatccga aaagacttgg
    35761 cctatggaga acaaaatgac tactttgacc atgctaactg tatcggttgg gtacgttcag
    35821 gtgctgaaaa tcaatcccca atcgcagtcc ttatctcaaa tgaccaagaa aacagcaagt
    35881 caatgtttgt cggtcaagaa tggactaatc aaacctttgt agatttactt ggtaaccacc
    35941 aaggtcaagt tacaattgat gaggaaggtt atggacaatt ccctgtctca gctagatccg
    36001 taagtgtctg ggcagtcaat accatctaat agctcataat aaccaagcta ggtccaagcg
    36061 gatttggctt ttttgtattc acaaaaagac ctacccaaat ggatagatct ttacttgatt
    36121 acaatttacc tgctactgca tccaacaatt cttggatctt aggttggttg cttcctcctg
    36181 ccatggccat gtctggttta ccaccaccac gtccatcgat gattggtgct aattctttga
    36241 caaggtttcc tgcatgaagg tcttttgtct tgcttgctac aaggacattg actttgtcac
    36301 cgatagcggc aactaggaca agaagatcag agtagtcttt ttgtttccag ttatctgcaa
    36361 aagtacgaag ggcaccggca tcggatacag acacttgact agcaatgtaa cgatgaccgt
    36421 tgacttcctt agcatctttg aagatatcgc ctgcggctgc agctgcggct ttttctttca
    36481 actcagcatt ttctttttga agttgacgaa gttgttcttg aagtccttct accttgtgag
    36541 gtacttcctt gacttgaggt gctttcaagg ttgctgcgac agctttaaga gcatcctctt
    36601 gttcacgata ggcttcaaag gcttccttac cagtcactgc caagatacgg cgagttcctg
    36661 aaccgattcc ttcttctttg acaattttga agagaccaat ctcagaagtg ttgccaacat
    36721 gagtaccacc acaaagttca atagagtagt caccgatagt cacgacacga acttccttgc
    36781 cgtatttctc accaaagagg gccatagctc ccatttcttt agcagtgtca atatccgttt
    36841 caactgtctt cacttcaagt gcttcccaaa ttttctcgtt aacttgctgt tcaatcgcac
    36901 gaagttcctc agcagttact gcttggaagt gggtaaagtc aaagcgaagg aattcaactt
    36961 cgttaagaga tcctgcctgt gttgcgtggt ttccaaggat attgtgaagg gcagcgtgaa
    37021 gcaaatgagt cgcagtgtgg tttttcatga cacggtgacg gcgattgcta tcaattgcca
    37081 aggtatattc ttggttcaag gcaagcggtg caaggacttc aactgtatga agggcttgac
    37141 catttggggc tttctgaaca ttggtcacag tagccacaat cttacctgac tcatccaaga
    37201 tttgtccgta gtcagctacc tgtccaccca tttcagcata aaatgacgtt tccgcaaaga
    37261 taagagaggc agttccttct gaaacagctc ctacttctgc attgtcagca acgatagcta
    37321 ccaatttaga agacaattgg ctagtattgt agttgaagac actttctaca gtgatgtttt
    37381 gaagagtttc attttgcata cccattgagc cacccttgac agctgacgca cgcgcgcgtt
    37441 cttgctgttc tttcatggct gcttcaaaac cttcacggtc tacagtcata ccagcttctt
    37501 cagcaatttc ttcagtcaat tcaactggga atccgtatgt atcatagagt ttaaagacat
    37561 cttgaccagc aatgacagat tgaccttttt ctttcaagtc tgccacaatg ccttgggcaa
    37621 agtgttgacc tgagtgaagg gtacgggcaa atgattcttc ttcgctctta acgattttct
    37681 caataaagtc acgtttctca agcacttctg ggtagtagct ttccatgatt tttccaacag
    37741 ttggaacaag tttgtaaagg aaaggctcgt tgatacccaa tttttgacca tgcatagaag
    37801 cacgacggag aagacgacga agaacataac cacgaccttc atttcctgga agggcaccat
    37861 caccgatagc aaatgaaaga gaacgaatgt ggtctgcgat aaccttgaag ctcatgttgt
    37921 cgccatcttg gtcataaacc ttaccagaca atttctcgac ttcacggata atcggcatga
    37981 agaggtccgt ttcaaagttg gtcttagccc cttggataac agccaccaaa cgctccaaac
    38041 cagcgcccgt atcaatgttc ttatgtggca attccttgta ttcgctacga ggaacagcag
    38101 ggtctgcgtt aaattgtgac aaaacgatgt tccagatttc aatataacgg tcgttttcaa
    38161 tatcttctgc aagcaggcga agaccgatat tttctgggtc aaaggcttcc ccacggtcaa
    38221 agaagatttc tgtatctggt ccagaaggtc ccgcaccgat ttcccagaag ttgtcctcaa
    38281 ttggaatcaa gtgacttgga tccactccca cttcaatcca gcggttgtaa gaatctttat
    38341 cgtctggata gtaggtcatg taaagttttt cagcagggaa atcaaaccat tcagggcttg
    38401 tcaaaagctc ataagcccaa gtgatagctt cgtcacggaa gtaatccccg atagagaagt
    38461 tccccagcat ttcaaacatg gtatggtgac gcgcagtctt ccctacgttt tcgatgtcgt
    38521 tggtacggat agccttttgg gcattggtaa tacgtggatt ttcagggata atggtcccgt
    38581 caaagtattt cttaagggtt gctaccccag agttgatcca caaaagagtt gggtcattta
    38641 caggaaccaa acttactgat ggttctactg agtgagcttt ggtcgcccag aaatcaagcc
    38701 acatttggcg tacttgtgca ctagatagtt gtttcatatt gtctccttat ttacttgttt
    38761 aatgtgattg gctttccagc atttccacat agtcaatcgc gacacagagg gaaatgacta
    38821 ggtctgcata agcgtcctca agaaccgtta cggtataggt agaggtcaga tggaagagtt
    38881 ccttcttaat ttccgcaatc agctgatcgc gatcatccag caattggaaa ttcaaatccc
    38941 agatattgcc ctcgatacga agacctagat tatcaaactc atacttatct cgccagaagg
    39001 tcaacttctt acgaatgaca aaactcgagc catcccgaag ctgaatctca aaacgaggaa
    39061 gcaaggtcaa gatttcttta ctaatctgac tgacttgttc accagccgca tcatagatgg
    39121 taaaggtttt aggaatctta aaaaatgatc cctccacctg ataggcaatt tctcccctgt
    39181 cattcttgat agcgaagcgt tcgcctccaa gacgaaactt ttgtttgaca agaaatgttt
    39241 tcatcaacac ctccaaaaat caaaagacaa gctcatatca cgaagggcga aaaaccgcgg
    39301 taccaccttc attcaatgaa cttgtcattc tcttgttctt atgcaattgt atgattgagt
    39361 agcatgactt cctagcttag atggctcgca gcaccgccat ttctctggac taagacaagt
    39421 gaaaatcaat tctcaacttt cttattatat cgttttttta atcttgcgtc aactggaaat
    39481 gatctccgtt gaattagacc aattccctac atctctgatt actttttcag gatatatttt
    39541 ttcttactgc catttttctt tttatcccaa attttcatag tactaaacac agctactaga
    39601 atatttccaa atataaaggt gcctatcacc caatatatgg actcagttgt taggtattgt
    39661 cgatccaagc catcctttaa atggaatagt atagcagttt ggttaacaat cataaaggtt
    39721 ggccagaaac tttttttgaa aaaagtagac attttcatta tttgttgccg ctttctgtaa
    39781 ggttaatact caataaaaat caaaaagcaa actaggaagc tagcctcaag ctgtacttga
    39841 gtacggcaag gcaacgctga cgtggtttga agagtatagg cttagtatac tactaggcaa
    39901 gcaaataagc aaataaacaa ataaacaaat aaacaactag aatagaaaaa gatagggctc
    39961 taaaaactga cttctattcc ttaaaaacga accagcttga ctgattcgtc ttcttacgtt
    40021 tatctcctac ttccgataca ttttaaactg taggaagagg tcgctatatt tccctgtcca
    40081 tttatggtca aatttctcat aaacttctag gtgtttcatg gtttcaacat cgggatagaa
    40141 ggccttatct tcctttgttt cctctgggag caattccttc gctggtaggt ttggtgttga
    40201 atagccgaca tactccgcat tttggagagc attttcaggt ttcaacataa agttgataaa
    40261 ggcataagct gagttttggt ttttaactgt tttgggaatg accatattgt caaaccaaag
    40321 attgctggcc tctgtcggta ccacataacg tagattttca tttttttcta acatttggct
    40381 ggcttcacca gagaaggtca cgccgattgc aacattattc tgaatcatat agcccttcat
    40441 ctcgtccgca acgatagcct tgatatttgg agtcagtttg tagagcttat ccactgtctc
    40501 ttccaactgc tgcagatcct tggagttgag ggaattgagt cctagtccca gcacctcacg
    40561 cgccccatca aagagcatga tagaattctt atactccggc ttccaaaggt catcccaatg
    40621 ctcaggcgct tcatctacca tggtttcgtt gtagacaatt cctaaggttc cccagaagta
    40681 agggatggag aatttattac ctgggtcaaa ggactggttg agaaactctg gtccgatatt
    40741 ttcgattcct tcaatttttg aataatcaag cggaaccaag aggtcttcgt ccttcatctt
    40801 gttaatcatg tattcacttg gaatggcaat atcgtaggtc gttccaccct gctttatctt
    40861 agtgtacatg gcttcgttgg agtcaaaagt ctcgtactga acttgaattc ctgtttcttc
    40921 tgtaaactga gtcaagagtt caggatcgat atagtctccc cagttataga taaccaattt
    40981 ttgactatct cgactattga ttttactatc taaatgagtc gcaattcccc acaagacaag
    41041 gataatcgct gcaattcctg ctaaaaatga atagattttt ttcatgcttg ctcctccttc
    41101 tcacgagaga taaagtaata acctacaact aggataatac taaagagaaa gactagagca
    41161 gacagggcat tgatttctaa ggaaatcccc ttgcgagcac gagagtaaat ctcgactgat
    41221 agggttgaaa agccatttcc tgttacaaag aaggtcacgg caaagtcatc taacgaatag
    41281 gtgaaggcca tgaaataacc agtaatgata gacggagtca ggtaaggaag catgatttcc
    41341 ttgaacatct gaaattgact agctcccaag tcataggccg catgaatcat gtcgccattc
    41401 atttccttga gtcgaggcaa gaccatcaag accacgatag gaatggagaa ggccacgtga
    41461 ctagatagaa cggtcaaaaa gccaagtgaa aacttgagtt gggtaaagag aatcaagaag
    41521 ctagcaccaa tcataacgtc aggcgcaacc atgaggatat tattgagtga tagaaaggct
    41581 tcttggtatt tcttacgaga ctggtagatg taaatggcac caaaagtccc gataatggtc
    41641 gctatcaagg ctgataggaa ggccaagaaa aatgtctgag ccaaaatcag catgagtctc
    41701 ccatctccaa acatggtttc aaagtgagtc cagctaaaac ctgtaaagct attcatatca
    41761 tcaccagcat taaaggcata gccaatcaag taaaagatag gcaggtagag gaccagaaag
    41821 accagtccca gataaaggtt ggcaaatttt ttcatcgttc tctcctttcc ttagtcaccc
    41881 acatggtgat gaacatggtc aggatgagaa tcacaccgat ggttgaaccc ataccatagt
    41941 tgtcattggt tagaaaattc tgctcaatag ccgtccccaa ggtgataacg cggttcccac
    42001 caatcaaacg ggtcagcatg aagagactca aacttgggat aaagaccgac tgaaccccac
    42061 ttcgcacacc gttcatagat agagggaaga tgacatgacg gaaggtctcc cacttagttg
    42121 caccaaggtc ataactagca ttgatgagat tattatccat gtcgtctaag acattgaaaa
    42181 tcggcaaaat cataaagggg agctcgatgt agcttgcgac aaagataaag gaaaaatcgg
    42241 taaaaagcaa ctgttgtgaa ccaattccga taaattccaa gaattggtta atagagccat
    42301 tttgaccaaa aatcccgata aaagcatagg ctttaaggag caaattgatc caggtaggaa
    42361 ggataatcag catgagccag agttgacggt gcttgagacg ggtcaaaaag agggctgttg
    42421 gatagctgat aagcaaggtc acaaaggtca caatccctgc ataaagcact gagttgaaac
    42481 tcattttgag gtaggtcaag ttttgtgacg caaagtaaga tttataattt tctaaactaa
    42541 actggccttc aatgttgaaa aaggattgtc cgaaaatcaa gaccaagggt gccaatacaa
    42601 agagggcaat ccaaagcatg tagggcacta caaagagttt agagcttgtt ttcttcatct
    42661 ctttcctcct cgatcgcatt gatcagacct gcttcttgct cttcgatttc cacgtattct
    42721 tcgatacgag catcgaactc ttcttcggtt tcattgagac gcatgatgtg gatgtcttct
    42781 ggttcaaagt ccagaccgat ttcctcaccc acgatggcct tacgggttga gtggatcatc
    42841 cattcatttc caagttcgtc ataggcgata atttcataat gcaccccacg gaagagctgg
    42901 gtatcgacct taacttgaag cttgccttct tcaggaaggg taatgcgcaa gtcctctgga
    42961 cgaataacga cctcaacagg ttcatttggc ttcatcccac catcaaccgc ttcaaagcgt
    43021 ttgccgttaa attcgaccaa gtagtcctca atcatggtac ctggcaagat gtttgactcc
    43081 ccgataaagg tggcaacaaa gtggttgatt ggctcatcgt agatgtccac aggggttcca
    43141 gactggacaa tctcgccatc attcataacg aaaatccagt cactcatggc aagagcttct
    43201 tcctgatcgt gagtgacaaa gacaaaggta atgcccaatc gttgttgcag ttcacgcagt
    43261 tcgtactgca tgtctgttct taatttcaag tccagcgctg acaagggctc atccaacaaa
    43321 accacacggg gttggttgat gatagcacgg gcgatagcca cacgctgacg ttgtcctcca
    43381 gaaagtttgc ggatggaacg tttttcataa ccttccaact gaaccatctt gagaacttcc
    43441 gctacacgtt gctcgatttc tttcttatca atgttacgca agcgaagtgg aaaggcaaca
    43501 ttttcaaaca cattcatatg tgggaacaag gcataggatt ggaagacagt atgtacgtcg
    43561 cgcttgttgg ttggaatatc attgatacga acaccgtcta gcatgatatc tcctgtcgtc
    43621 gcatccagta aacctgcaat aatgtttagg atagttgatt tccccgaacc agatgcacct
    43681 agaagggtgt agaatttccc ttcttccaac tcaaagttga tgtctttgag aaccttggtg
    43741 ttgctgtctt caaaaacttt agagacgttt ttgaattcga taattggttt tttcaattgg
    43801 cataaattcc ttctttttca tagattaacc gatcggggct ctgtcaggtc cccactacct
    43861 cttgcaggga gtaaaaccac ctgcatacat cttcgctacc gataggcttt cacccccctt
    43921 tccatgacat agcagcagct tttcaaatac agcttcctac ttgctttcac ccaagatccg
    43981 gacttctctt tcaagcgtaa tacctgagtg ttccttgact ttttcgataa ccgattggat
    44041 caagtcctcg tagtctttgg ccgttccatc tgcgacattg atcataaatc ctgcatgctt
    44101 ttctgacact tctacgccac cgatacgata gcctttcaag ccagcttctg aaattaactg
    44161 acctgcaaaa tgcccgactg gacgcttaaa gaccgagcca caagatgggt attccaaagg
    44221 ttgcttgagt tcacgtaggt gcgtcaagcg gtccatttcc tgcttgataa cctgatgggt
    44281 tcctggggct agggcaaatt taactgacaa gacaactgca ccagactcct gaatagctga
    44341 atggcggtaa ccaaaagcca agtctttagc agacagggtt tcgatttctc catccttggt
    44401 caagacctta caagactgca atatgtgagc aatctcgcca ccataggcac ccgcattcat
    44461 aaagacagca ccgccaacgc ttcctggaat accacaagca aactcaaagc cagtcaaact
    44521 atgacggagg gcaatgcgag ttgtttcaat caagttagcc ccagcttctg cttcaatggt
    44581 atagccatca acagaaacgt tattgagctt gtcacacaag atgacaaatc cacgaatccc
    44641 accatcacga acgatgatat tgcttgcatt gccaagaacc atccaaggga tattttcttg
    44701 gttggcaaat ttcacaacgc gagccaactc aaaacgattt cgtggaaaga ccaaataatc
    44761 agcctctcca cctacttttg tataactata gctatgcaag ggttcctgaa aacggatatc
    44821 aattccttct aagatttcaa gcattttttc tcttacagac atgtcactct tccttttaca
    44881 aaattcattc cattatacca tttttagaga catttgacga ccataaaaat accttgtttg
    44941 gattttgcat aagaaaaaga ggttcccctc tttttatgat tttttacaaa agatttcctt
    45001 ggttccatag gcgaccagaa cgagctccag tgctagaatc acttcaacca agactggatt
    45061 tgtcaaccag cctacttgga aaagagatgg tgccagatca aagaaggcat gcaagccata
    45121 ggctgttagg agataaatcc atttcttctg gcgaacagct tgataaaccc aaactgtcaa
    45181 aagtaattgg aaaccaagcg ccaagattcg ctcaaaacca agcaaataaa tctgccagac
    45241 cgaaagtgac tgaatggttt ttaacatatt ttcagacagt aattgcataa cctgtggatt
    45301 ctgagtttga actgccgaaa gaacaatgta aagattgagt aaactagtaa ggcctagaaa
    45361 aatcaactcc aagccaccat gccccaatcc ataggccaag gcgtctgcct tttccaaact
    45421 tctctttttc tccaaccatt tgaagaaaac aagacgagcc gtttcctcaa aaaatgctac
    45481 catggctagg ccatagataa tatagataag cggatgaact tacaagaggg caatactacc
    45541 gtctttttga ggatgcaaaa tcaagatatg caccagtttt tccaaaatct gcgaagagac
    45601 aaagaaagcg actgcaccca agtccaagac agctagatta atctggtatt tctttttggc
    45661 aaaccaaatg cttcctatca gaaaagctag caacagcaac atggtaataa tgatatgaat
    45721 ggtcattttc ttctcctatt ctgccttttc aatatctttt ttcatctcgt caacattgaa
    45781 cttagcaaac aagtattgac ggtcttggac tgggaaacgt tggtccaact ggtcaattgc
    45841 tcccacctcg ataatgcctt ccttgatgac aaaatccatg acatgtccac cgaaggtcaa
    45901 atcatctgat atgaagtgca gatggtagcc tgccacactg accccatgga aaatctcagg
    45961 cgtccagaaa ccaacaatag tccccacaac attgtcacga ctatattccg gttgatgggt
    46021 tgcgacatca gcaaacttgg tatcgggtgt tgacttagga atcatacgca catgcatatg
    46081 tgaaaattcc ccccgaatct tgatagagcg gaaaagattt tccccatcat aataagactc
    46141 aattcgttct ttcaattcct tgtctgtcat ctcaaagcgc tggcggaaaa tgacctctgc
    46201 ctgatgcggt accactgcag cgtaaggaat aagggcatct ggtgacactt ccacaatttc
    46261 tggctggtct cctgaccctt tggcctgata agccttgcca tccaagacaa tcaattcccc
    46321 atcaatggaa tccaaggttc ccaaaccaag gtcaccatgt tctagcaatt ctcctactgt
    46381 catagtacca ccataaaggc cagccatcaa ggctccaagg gtattgtatt gaaataattt
    46441 cactggttcc tgcacgttct tatccattca ctttcttgtc tgttattcta taaatcttac
    46501 tcctaagtat accacatttg cccctagatg tgaacgagag aaacgctcta gacattgcca
    46561 agaaggaaaa aaaagggtac aatgtaacaa aatcaaggga ggtctggaat gaagaaacaa
    46621 agcaagtaca aagaggtcgt ttcctatctg aaaaatggta tcgagtctga acgatttccg
    46681 acgggtagtc gcctgccttc tatccgtcaa ctgagccttg actttcactg cagcaaggac
    46741 accattcaac gagccctgct ggaattacgg cacgaacaat acctctatgc caagccccag
    46801 agcggctact atgtcctaga acaagggcaa catcaagacc tagaaatcga ggttaccgac
    46861 gaacatgcca gtgcctatga cgatttccga ctctgtgtca atgaaacctt gattggacga
    46921 gaaaactacc tcttcaacta ctatgacaat caagaaggat tagaagacct aagacagtcc
    46981 attcacaaac tcctatttga gcaagctctc tactgcaagg ctaaccaact agtactgact
    47041 tctggaaccc aacaagcctt atttatcctc tctcaaatat cctttcctag acaagccaag
    47101 gaaatcttgg tggaacagcc aacctaccat cggatgaatc gcctcttgat tgcacagggg
    47161 ctggactatc aaacgattga acgaggcatt gatgggattg acttggagga gctggaaggc
    47221 cacttcaaaa caggaaaaat taagtttttc tacaccattc ctcgatttca ctatccccta
    47281 ggccattcct attctgagca ggacaaacga gctattcttg acttagcagc caaatatagt
    47341 gtttatatcg tcgaagacga ctatctgggg gatttggact ctaaaaaggg ccagaccttc
    47401 cactatctag atacagagga acgcgtcatt tatatcaaat ccttctcaac cagcctcttt
    47461 ccagccttgc ggataacagc actcattctt ccaaatacta tcaaagaagc cttcgtggcc
    47521 tacaaaaata tcctagacta cgacagcaac ctcatcatgc aaaaggccct gtcactctat
    47581 attgacagtc aattgtttga aaaaaatcgt ttggctcgct tgaccaatca tgaatcttac
    47641 caaaaacaaa tcgaggaaag gataactaaa acaccttgtc cccttcctca ttatccccta
    47701 cacgatggtt tattgctaga cctgagacag tatcctaaaa tcgccagtct caaacacagt
    47761 caactgggct tggacttctt tgaagaggcc tatttaagca cctgtcctta tcaatttgcc
    47821 aaggtgtccc tagacaatct ggaaaatgtt ttaaactatt taaaagcaga attggaatga
    47881 catccaactc tgctttttct tattcttcaa cttcagttaa acttgctgct ttttcaagat
    47941 agctttggta agttccttca tccttaagtt tttggatgac cttgtctacc acttctttca
    48001 aatcatcact attttttcta agagcaacgg cattggcgtc gccgtccttc atcttcaagc
    48061 tgacagttgc gacagctaag ccagcgtttt tagcagcata actaagtgca acaggctcat
    48121 ccatatgaac agcatctatt tttccagcct gcaattcatt gactgcttca cccatattag
    48181 ttagggaagt taattgagct tttggcaatt gtgccttgac cattgattct ggaacagtcc
    48241 ctttttgggc tgcaatatta gcactttcta ggctagttaa atccttgtat ttttccacat
    48301 cagccttacg aaccaagaaa ctaatcttgt tttcatagta tgggattgaa aaatcaaaga
    48361 cttcttttct ctcgtcagta gcactaattc ctgcaactgc taggtcagcc ttaccagttt
    48421 gaagactggt caaaacattg tcaaaactca tgcttaagat ttccaactta accccaagtt
    48481 catcagcgat agcctgagcc atgtcgatgt ctgcaccgac tacctggttc tttccatcaa
    48541 ccaatgattg aaattcaaag ggtgcatagt caggactggt tgccacaact aatttccctt
    48601 tttgtttgat agcatccaca gcagactgag aaccattaga acctgactgg caagctacta
    48661 agaagaaact tgcaagaaaa ttacataaaa caaatatcca tttttttgat ttcataaata
    48721 aacaacctct ctgttaattt tgtataatta taacgatatc caagttactt gtcaagtgtt
    48781 ttttaaattt ttatctcaaa aatatttttt cgttcaaaaa aaggagccat cagttgattt
    48841 caagctcctt tttatacaga attaaactat tttatagttc gacaatctta cctgtttcaa
    48901 agtagacaac ccattcacag atatttttag catagtcacc gatacgctcc aagtaggaaa
    48961 taacttggaa ataatcacga cccgtaacaa tggcttctgg atttttctta atctcttcag
    49021 tcgcaaggtc acggatagtt tcaaaatagt ggttaatttg ctcatccatg gaggccaccc
    49081 ggtatgcgtc gtcaacagaa ccattaagat aaagatcaag tgctgcttca acaacgcttt
    49141 taacttcacg tcccattttt ttaatttctt cctctacagc tggaatgcgc tcttccccct
    49201 tcatacggat ggttgcctgg gcaatggcta cagcgtgatc ccccatacgc tccacatctg
    49261 atacagcctt aaggacagtc aagactgtac gcaaatcttg agagactggt tgttggagtg
    49321 cgatcatttc aaatgatttc ttttccagtt tcacttcgta ttcatttact tctgcatcat
    49381 cttcgatgac ctcttttgcc aggtcacggt catgcgtgac aaaagcacgt accgtacgat
    49441 tgatttgtga gagcacttct tgtcccatag cgtagaactg gttatgtaat ttctctaaat
    49501 cttcttcaaa ttgagatcgt aacatctttc atctccttat ccaaattttc ctgtaatata
    49561 gtcttccgtt tccttgtgtt ggggatcaag gaacatctgc ttggtatcat taaattcaat
    49621 caaatctcca tctaggaaaa atcctgtctt atcagagata cgtgaagctt gctgcatgga
    49681 acgggttacc agaagcatgg tgtacttgtc ttttagacca tacaaggttt cctcaatttt
    49741 accagctgaa atcggatcca aagccgaagt tggctcatcc aagaggatga ttttaggact
    49801 agttgccaag acacgggcca cgcagacacg ctgctgttga ccacctgaca atccaatagc
    49861 tgaatcatat agacgatcct tgacctcatc ccagatagag gcaccttgca aggctttttc
    49921 tacggcttca tccagaacct gcttatcctt aattccattg atacgaagcc cgtagacaac
    49981 attctcatag atagtcatag ggaaaggatt aggttgttgg aaaaccattc cgatttcctt
    50041 acgtaattca accgtatctg tacgcggact gtagatgttg tggccattgt acaccacgga
    50101 tccagttgtg gtcacctctg gattgagatc tcccatgcgg ttgagagact tgaggagggt
    50161 tgacttccct gatccagatg gaccaatcaa ggctgtaatt tccttaggtt ggaaagatag
    50221 ggaaacacta ttcaaagcct tctttttatt ataataaacg gacaggtctg atacctgtaa
    50281 aatcgcatct gtcatacggt ttcctttcta accaaagtga ccagatacat agtcattggt
    50341 ggactgtagc ttggcatttt ggaaaatagt tgcagtcttg tcatactcaa tcaaatcacc
    50401 caagtaaaag aagcctgtat agtcacttgc acgagcagcc tgctgcatat tatgcgttac
    50461 aatgatgatg gtaaagtttt tcttgagctc aaacatggtc tcttctagtt gcatggtcgc
    50521 aatcggatcc aaggctgagg ctggctcatc cattaagagg atatctggct taacagagat
    50581 ggcacgagcg atacagagac gttgttgctg accacctgat aaggtcaagg ctgacttgtg
    50641 gagatcgtct ttaacctgat cccagagggc agcctgacga agggaggttt ctacgatttc
    50701 atctaggact tgcttatcct taactccagc acgttcatgc gcaaaggtaa tattacggta
    50761 aattgactta gcaaatggat tggggcgttg aaaaaccatt ccaatgtgtt tacgcatttc
    50821 ataaacgttg atttctggac ggttgacatc aattccacga tagagaatct gcccagttac
    50881 tttagcaata tcaatagtat cattcatgcg attgagactg cgtaagtagg tagatttccc
    50941 cgaccccgac ggaccaatca aagctgtaat tttatttctt tcaaattgca tatcaatccc
    51001 cttaatggat tcatttttac catagtaaac atggacatcc ttagtagaaa gggctacttt
    51061 ttcttcagga aaggtaagga tatgcttctc atcccagtta tatgttgaca tggcttctcc
    51121 tttaggcagc ggttaatttc ttgtgtagat agcttccgaa cttacgagct ccaaagttaa
    51181 aaatcaggat aaagatcagg agcacagcgg cagaacctgc tgatacaatg gttccatctg
    51241 gaatagtgcc ttcactattg actttccaga tatggacagc caaggtttct gcttgacgga
    51301 agatagagat ggggctagtc acactgagga tattccagtt agaccagtca agagctggcg
    51361 ccgattgccc tgctgtatag atcagagctg cagcttcgcc aaagatacga ccagatgcca
    51421 agacgacacc cgttacaata cctggaagcg cttctggaat aacaacatga accactgtct
    51481 cccagcgaga aatcccaaga gccagaccag cctcacgttg ggtatggtga acgtgtttca
    51541 aactatcctc tacattacgc gtcatctgag gcaaattaaa gactgtcaag gccaaggcac
    51601 ctgaaatgat tgaaaatcca tactcaaact ggactacaaa gatcaagtaa ccaaagagac
    51661 ccaccaccac tgatggtaaa gaggacaaga tttcaataca agtccgcaca aagttggtaa
    51721 caggaccttt tttagcatat tcagccaagt aaatcccagc tcccatagaa agaggtacag
    51781 aaataatcaa ggtaatgacc aataggaaaa aggaattgta aagctgaatg ccaatcccac
    51841 cacctgcttg aaaagcagaa gaccttccag tcaagaaaga ccaagagata tggggcaagc
    51901 cccgaaccaa gatatagaga atcaaggaag ccaagattgt cacaatgatg ctagcaatcg
    51961 tatagaggac agctgttgca agtttatcta atttcttagc gcgcataatt tttctttcct
    52021 ctttctttcg taatcaattt aatcacactg ttaaaaacta aactcatcaa gagcagtacc
    52081 aaggccagtg accagagaac attattattt acagttccca tgacagtgtt cccaattccc
    52141 atagttaata tagaagttaa agttgcagct ggtgtggtca aggaagttgg gataacagct
    52201 gagtttccga caaccatctg gatagctaaa gcctcaccaa aggcacgcgc catcccaaag
    52261 accactgcag tgaaaatacc agaacgggcc gccttcaaga tcacacgcca gatagtctgc
    52321 cagcgagtgg ctcccatagc gaaacttgcc tcacgataat aacgaggaac cgcacgcaag
    52381 ctatccgttg tcataaaggt tacggtcggc aaaatcatga caaagaggac ggaaatccct
    52441 gacaaaatcc caaaaccagt cccaccaaag acactgcgaa caaagggaac gacgacttgc
    52501 aagccaataa atccgtacac tactgaagga atcccaacca ggagttcaat agctggttgc
    52561 aaaatcttcg ccccttttgg tgatacttcg gtcataaaaa ctgctgcacc aatagcaaag
    52621 ggtgttgcga taagggctga gagaatggta acgataaagg aacccaaaat cataggaagg
    52681 gcaccaaatt ctttactaga aggattccaa gttcctccca aaagaaagtc aaagatattc
    52741 acaccattga caaagaaggt cgacaagcct ttttgcgcta cgaaaaccaa aatcatggcc
    52801 acaaggatga ctatcaaaga aagacaggca aaggtcaaac cttttcctaa tttctccaga
    52861 cgagaattct ttgatggaag caacattttc ttagctaatt cttcttgatt cattattgtc
    52921 tcccttccaa cactgtcaca gttccggcag catctttttc aaccttcatt tccttaatcg
    52981 gaatatactt caatcctttg acaatccctt cttgggtctc atccgagaga acaaaattga
    53041 gaaattctgc agccaactca ttgggctgcc ccaatgtata catatgctca taagaccaca
    53101 agggccaatt attgctactt atattttctg gacttaagtc atagccattc aacttcatgc
    53161 ttttgaccga atcatctata taggtaagag ataaataaga gatagctcct ggactttttg
    53221 atacgattga ttttaccgct ccatttgaat cctgctcctg actttgcatg gcagactgac
    53281 cttccataat gacagtatca aaggtagcac gagagccaga gccggctgcc cgattgataa
    53341 cagagatggg taagtcctta ccaccaacct ctttccaatt ggttacctca cctatgaaga
    53401 tttgacgaag ttgctctgtc gttaggttat caacatcaac ctccttattg acaatcagag
    53461 ccaagccagc taccgcgacc ttgtggtcaa caagagcaga agcatcaatt ccgtcttttt
    53521 cctcagcaaa tacatctgag tttcctatat caactgcccc agactgaacc tgggacaagc
    53581 ctgtaccaga acctccccct tggacattga ccgtttttcc aacatggatc gtgccaaatt
    53641 catctgccgc tacttcaacc aagggttgca aggcagttga gccaacagcc gttatggatt
    53701 ctccacgatc aatccagcta gcacagccta ctaaacaagc cgtcagccaa aaagcgataa
    53761 gagacagagc aagctttttt ctttttttca ctgtttttct cctcgaaaat aattatgaat
    53821 actgtgaatt ttttaagtag ttctttatga gttgacgcat gaattcttac caaatttctg
    53881 cgcaattgat tatttatata atataggcta tattactctt tcctaacctc cttttttcat
    53941 atgtggataa aatctcttgt ctatcccttc ccccattgtc acccattata gtcatttcgt
    54001 gtctcttttt ccccttttta atgcaaggga aattactctc cttagatgat aatccaaaag
    54061 ctagaaaggt atctcaaacc tctctactct cccagactag tttacaacta aaaggaaaag
    54121 attctatttt atgagaaatc tagtttacaa gcggtaagaa cgctaataac taaacttctt
    54181 gtactctttg aaaatctctt caaagcagtg ttttgagcta tctatggcta gcttcctagt
    54241 ttgctctttg attttcattg agtagtaaaa ctacatgtaa tggcaatcaa gatatcaaga
    54301 atcatcctac taaaaaaatc catactttca ctataacata gaataagata tttgactagc
    54361 attttcattt gaatctgagg ccttttggaa aataattttt caaaacattt ccagtaacct
    54421 ttgcaaagcc caagccattg cctttaacca aaacttggta ccaaccattt ggcagacttt
    54481 ctgccagctg aacgatttct ccagccgcat acttgacaaa cgcttcttgg ccaatttcaa
    54541 ccgactgttc gacctgactc gatttcaagg ctaaaccaag agcgaaactg ggctcaaagc
    54601 gtttcttctt aaaagtaccc agatgcagtc cattgcgagc aatcttgagc ttccctaaat
    54661 ctggcaaaag ttctggcaag agataaagct ggtctccaaa agtctgcaag atacccggta
    54721 gattgacctt caaatggttt tgggcaaatt cctgccacaa ggcaacttgt tcacggctga
    54781 ggttactctt acttgcctta aatttaggag ctggattgtt acccttaaac tgtagatggg
    54841 caacaaactg accctctccc ttaaactgat gagggtacat ccgagccgtt tctggcaggt
    54901 caataccagc taccattcca ttgatatgct ctactggcaa caagtcaaaa tcatactctt
    54961 ccagcaacca attgacaatc tcttcgtttt cctcgggtgc ccaggtacag gtcgaataaa
    55021 ccagacgacc accttcagct aacatggtca ctgcatcctc cagaatttct ctttgcaagc
    55081 tagcacattg actcggataa tgtaagctcc aatagtccat agcatcaggt tgcttacgaa
    55141 acattccttc accagagcaa ggggcatcaa gaacgattaa gtcaaaatag cctttaaaga
    55201 ccttgaccaa gcggtcggca gattcattgg tcaccacgac atttgtcgct ccaaaacgct
    55261 ccatgttttc aaccaaaatc ttagcccgtt tgcttgaaat ttcattggaa acaagtagcc
    55321 cctcccctgc tagataggct gccagttgag ttgatttgcc ccccggtgca gcagccaagt
    55381 ccaagacctt cataccagga ctgggttggg ctacttgagc caccatttga gcagcaggtt
    55441 cttgcgaata aactaaacct gtagcatgct caggcgattt ccctgaaacc ttcccatagt
    55501 ggccccaagg ggtttgagta atggcatcag aaaaggaaag ttgctcttct tttaagggat
    55561 tgacccgaaa ggccgaaacc gcttcctcct caaaagaggc aagaaaatct cttgcctcat
    55621 ctcctagtat ttctttatat ttttcaacaa atccttctgg aaatttcatt taagttcttt
    55681 tcctttcgta aatataggac tgaatttcct cctgcatctc aagaggcacc atcatgaccg
    55741 gctgtctggt ttgaaaatca ggagcttcac caaaaagggt cacaacccga tagcccagac
    55801 tttcccctaa aatactagct gcggcataat cccatggttg cagataggtg agataggtca
    55861 acaaatgccc tgacaaaatc ttggcaaaac taatggccgc acttccatag atacgaacac
    55921 caagaaccgc tcggctcaaa tcagccagcc cccattcatt ggtttccagc ataccactat
    55981 tccctgcaat gagaaaatct ccaagtggtt tagttttaaa aggagctagg ggcctatcat
    56041 ttagacaaac tggaaattcc ccaccaccgt ggtaacaatc ccctttgacc acatcataaa
    56101 tcagaccaaa ctgtccctga ccattttcaa aataagccat cataacagca aaatcttcct
    56161 gctgggctac aaaattattg gtaccatcaa tgggatcaat gacccaaacc ttgccctctt
    56221 gaaccgaggc tcgcagacaa ccttcttcag cacaaatctt atcctcagga taacgggaca
    56281 aaatctcacc aaccaagagt tcctgaactt ctttatccag tctggtcacc aaatctgttg
    56341 gagaggactt ggtttcaaca cgcaagtctt cctgcatatg gtcaagaatg tactgacctg
    56401 ctttcttaac aagctcttta gcaaattcaa atttactttc caagagaaat ctttccttcc
    56461 cctttttctt tggcagcctg aactgctcgg taaagtgaat agccactaac cgtttcaaat
    56521 tctcgtccca aacgtttctc ttcgctcttg cttggcacga ccgctttgaa tcccttatag
    56581 gagtccagta actttttagc ctctactttg ccttcatagg cagcttcaac atcattaaaa
    56641 aaagaaagca ctgaagcaag ttcttcagtg ctccacgaca aatctagtgg gtaactatac
    56701 tgtttgttca ttaactaata ccagctctca ttcttgcttc ttttagttct tgcttacgat
    56761 aactacgagg gagaaaagca cgaatctcat cttcattaaa accgatttgc atacgcttgg
    56821 catcaataat aattggacga cgcaaaagac taggatactg ctcaatcaaa tgaagcaatt
    56881 ccgataccga aatactctct acatcaatat tcaatttttg aaaaattttt gaacgagttg
    56941 aaatgatgtc atcagtacca ttttcggtca aggaaaggat gtgttgcaat tcttttcttg
    57001 ttaaaggact ggtcataata ttgtgttcca caaagggaac cttatgtttt tctaaccagg
    57061 ccttagcctt acgacatgat gtacagctcg gtgatagaaa tagtgtaatc atgcttttct
    57121 cttcttatct atactttgct acttctatta tacaaaaaaa taaagcgctt gactagggat
    57181 ttttagaaaa aaagcctatt ttttcaagaa aaataggctt tttgcgaacg attgacacaa
    57241 ttggatttgg ttaattcact cttaacgatg gttttaaacg atatatattt ttatatatgt
    57301 aaattaaaaa catctttcct ttcacttcct acgacttttc agatacagat agccaaagaa
    57361 gttttcatag agggcaaaaa agaggaggaa ggcatgaaga aagaaggtct ctggcaaaat
    57421 cataataaca ggatccttgg ctggatcaaa aagccaggta tcatctccca caaagagaat
    57481 ttgatggaaa agagtaaaga attggtcaaa accaatcaaa actcccccaa gtccaatcat
    57541 cacaggtaag actactagag ccaggagact ttttcgataa agagacaaaa agtccttttt
    57601 cacaatccta ttgacaaaga catagaaact tggcagtgtc actagagcta ctagctgaac
    57661 caaatgaaag agattcttga ccactgcgaa atggtgcaga ccagctgctg acgaacgaaa
    57721 atcaggcatc tgtaagacct gactaaaagg attggtcaga taattcatca agatatgaaa
    57781 attgtattga atggtttctg gttttagata gactcgattc gttaagttta gccactgaat
    57841 ctccatagga tagaaaatcc aagccagata aatggtcaga aggattgaga gggagaggag
    57901 aaagagcata gagccccaaa aggtcaattt agttttcatc aaaatcccac tccgcaaggc
    57961 tagaaaccac atgtgtcggt gcgattggca ggccagctac ttcttctgcc ttagtaaaac
    58021 ctgtcgtcac caagagcgtt ggaatgccat tgtcaatccc agcccggata tcagtcaaat
    58081 aattgtcccc aaccatgatt aactcttcac gttccaaacc taagtgctca accgccttgt
    58141 ccataatgat ggcattgggt tttccgatat aaaccggctt cactcgtgtc gctacttcaa
    58201 gcagcgtaat cagggagcca gcacctggca aaagaccgcg ttccgtcggg atgttgaggt
    58261 caggattggt tccgataaaa tgggcaccct tttgaatagc aagagttgct gtggcaaatt
    58321 tttcatagtc gacttgccaa tccagaccaa ctaccacgta ggcagggttt tccttgtctt
    58381 ccacataacc agccgccttg atggcttcct tgagtcctgc ttctccgacg acatagacgg
    58441 tcttttcaag ccccaaatca ttcatatagt cgatggttgc caaagtcgct gtgtagacag
    58501 tcgatagggg cgtatcgata ttaaaattct gagccaacat ctccttaaca ctctctggag
    58561 tgcgagttgt attgttggtt acaaagagat agggaatgcc ccgcttttgc aattcatgaa
    58621 caaaagtctc tccagcaggg attcggtctt tccccttata aatggttccg tctaaatcaa
    58681 ttaaatagcc tttatatttc atctatttct ccctaagcct tttttatttc ttgccaagta
    58741 atgattgctt gggcattgat aaccccatca cttgtaattt catgcttgct ttccagtcca
    58801 gtccgttcaa caaccgatgt aatcactcca cctggtcgaa cttccttgac atacttgagg
    58861 ttgattttct tgggaatata gtgggtcaaa aaatccgctc ccatgacctc aaaaatccag
    58921 tccaagtatt tactgttatt gacatgacca ttcatatcca agtcgtaaaa acgaacatgg
    58981 taatccttgc tgatcggttc ttccaaggac tcatacttcg gtccacggat aagtttttta
    59041 tcaaaatcag actggtaagg agccacaatc tcaggttcaa cagcatggac ttttcgactg
    59101 tcgcggtcca tgagaacaaa ggtcgccatc atatggatga gctcctgccc cgcttcatta
    59161 taaatagtaa agcgacggta gcaaaaaagt cgattgtagc tcaaggcttc cgtttcgatg
    59221 gtaatttctt ccgcaaaacg aggcaaacga accacctcaa tatcatattc tgcgataatc
    59281 cagaccagat tatagtcttc caaaatggcc ttatcactaa ctcccagttc aatcgactgc
    59341 atccctgaaa cttgcagtga cagcaaaatc acatctggaa gtttgatatg accgttcata
    59401 tcagccatat caaaaggaat tttcattttc atttgataag ttaagcccat gatcctactc
    59461 caaaataaat cgttctgcta cagtatctcc caaaaagaga cctctctttg tcatgcgaac
    59521 gtggtcaccc tcaatctgca tgaggccttg ttgaaccaaa tctctgacaa tttctccata
    59581 aagtccagca aaagactgtc caaatttttc ctcaaatcgc gccatggaaa ccccggattt
    59641 cttgcggagt cccaagaaca tttcttcttc catttgctcc ttttgactca ggtgatcttc
    59701 tgtaatacaa gcattgcctt cctcaaccgc actgagataa tgacgaatgg gaccatgatt
    59761 tttataacgt actccattga cataaccaga tgcccctgca ccaataccat agtattcagc
    59821 attgtcccag tacatgagat tatgacgact ttcaaagccg ggtttggaga aattagaaat
    59881 ctcataatgc tcaaaacccg ctcgctccag ctctgcaatg atgtactcaa acatctccgc
    59941 ttctagttcc tccttaggca gaggcaattt cccacgtcgc atccggttca taaagaccgt
    60001 atggttttct aaaatcaaac tatacaaact catgtgggga atatccagtc caatggcttt
    60061 agccacattt tcctttactt gctccatggt ctgaccaggc agagcataaa tcaaatcaat
    60121 ggagatgttg tcaaaaccag ccagtttcag acgatcgata ttttcataaa tatccttctc
    60181 caaatgactg cgcccaatct ttttcaacat cttatcatca aaggtctgga cacctagcga
    60241 aacacgattg acagccgaat ttttcaaaac agctatctta tccgcatcca aatcgcctgg
    60301 attggcttca atggtcaact cttccaagac agacaagtcc aagtttttag tcaagccatt
    60361 cagtaacacc tccagttgcg gagccgacag ggctgtcggt gttccaccac cgatataaag
    60421 ggttgacaac ttttcaatat cataagaacg aaactcttcc agcagatgct ctaaatagct
    60481 gtcgactggc tgatttttga tgaagacctt tgaaaaatca caataataac aaatctgggt
    60541 acaaaatggg atgtgcacat aggctgacgt tggttttttc tgcatagtaa ttattatacc
    60601 acaaagacta gattccagat aaaaatcacc atccccagat acatagtccg tccggagatg
    60661 gtgatggttt attcttctgt tatatcaatc acaatctctt ctgagtcatc aagagcttcg
    60721 gctttttctt gccattgttc cttgagatta tttaattgat tttttgatgc ttctgtcgct
    60781 tgaaaagcat aggatttagc ttgagcaagt atactgtcca cagtgatttc acctgactca
    60841 acctgttctt ttgttttcag aacaaaatct gtagcctgct ccttaacttc tgtcagtttt
    60901 tcacagactt gctccttggc atactccgga tcttctctca aatcatctag aaaatcttga
    60961 gcctgactgc aaacttgttt gcccttatca cttgttaaaa acaaggcaag agctgcacct
    61021 gaaaccgttc ctaaaaggat tgaggataat ttacccataa ggattctcct tttttatttt
    61081 ttgaaaaatt tacttgcaag acgaagagct gacagacttg caccagtctt gagtgttttt
    61141 gaaccagctg atgaagcttt cttgctcaag acacgcgcat ggtcattgag gtctgaaaca
    61201 gatagagata aatctgcaac agcactgaag agtggatcaa tcgtagccac cttgacattg
    61261 atatcatctg ccaagacatt gaccttagcc aacaactcat tggtgtgatg caaggtcaca
    61321 tccacatctg aagtcaaggt tttaatcgtc ttttctgttt catcgatgac acgaccaagc
    61381 ttttgtacag taatgatcag atagaccaaa aagacaatca aagctagggc aacaagaata
    61441 tatgcaactt ctaacattta tttttcctcc tctgtaatat agtaaggggc cttctttcga
    61501 ttttgataaa taacgatcat tataccgaga ccgataagga caactgacag ccattgggac
    61561 actcgaaggc tgaagaacat gagactatct gttcgcatac cttcgatgac catacgaccg
    61621 aaaccatacc aaatcaagta aaaggccgtg atatgacctc gtctgagact cttccatttc
    61681 cgtctaaaaa tcagaatcaa agcaaagcca agcagattcc atagagactc ataaaggaaa
    61741 gtcggttgac ggtagctccc ctcaatatac atctggtcac ggataaagcc aggtagataa
    61801 tccagattat ccactgttgc accataagct tcttggttaa agaaattacc ccaacgcccc
    61861 aaactttgag caatcataac gctaggcgcc gcaatatcta gaaaatccca agtattgatg
    61921 agtttacggt cagcaaagat atagagcaca agagccccag ttatcaaacc accgtaaatg
    61981 gccaaaccac cattccaaat ggcaaaaatc tctcctaaat tctgactata gtaatcaaat
    62041 cggaaaataa catagtagag acgagctcct aaaatagcca agggaaaggc tactaagata
    62101 aaatctaaaa tatcgtctgg tatgatcttc tttctaggtg cttctttcat ggtcaaataa
    62161 accgcaagaa tcaagcctgt cacaatacat aaggcatacc aacgaatggc taggggtcct
    62221 agttgaatag caattggatc aagcattttg cacctcattt cgagcaatga gacttgtcag
    62281 tcgttcgtcg aacaaacggg tcgcatcaaa gcccatttcc ttggcacgat aattcatggc
    62341 agctgcctca atcacaacag agatattacg acctgtttta actggaatac gaatacgagg
    62401 aatggctacg ccagaaactt caagttcctc tgcattgttt ccaagacgat caaaggtctt
    62461 atgtgtatcg taattttcca aatagacagc aagctgaacc tgtgaagaat ccttgacagc
    62521 actcgcaccg tagagactca taacatcgat aataccaacc ccacgaattt caatcaagtg
    62581 tttcaaaatt tcagctggtt caccccagag agtaatctca tccttggcaa agatatcgac
    62641 acggtcatcg gctaccaaac ggtgaccacg tttgacaagc tcaagacctg tctcgctctt
    62701 accaattcca ctatctccct gaatcaagac gcccatccca taaatatcca tcaagacacc
    62761 gtgcacactg gtacgttctg ccaaacgaga atccagatag ctagataact ctccagataa
    62821 acgactggta gctgcacggc tggttaaaat agcaatctta cattctctag cagcctttaa
    62881 catctcctct ggaaccacca aaccacgggc aacaatgact gctggtgtct caggtagaaa
    62941 catttttttc aaaacttcat aacggctgtt ggaaggcatg ctgatcagat aagaccactc
    63001 cttcatcccc aaaagttgaa tccgctctgg tgtatagtag tcaaaatagc ctgtcatttc
    63061 aagaccaggt cgcgtaatat ccgctgtatt gatttccttt tcaagcaatt ctggttcacc
    63121 atagacaata tctagtctaa gcttttcaat cacttctttt actaaaaccg acatcatttc
    63181 ctccttcaaa tgagttcttc tctctattat atcaaattgt aggaggaagt ttcagatttt
    63241 tgcaggcttt ggagtattta tttaaaagaa aaaggactag atttctctag cctttcattt
    63301 caattagaat tttttacgtt tacgagctac ttctgattta cgtttacgtt ttacagaagg
    63361 tttttcatag aattcacgtt tgcgtgtttc ttgaagagta ccagctttag taaccgcacg
    63421 tttgaaacgg cgaagtgcgt cgtcaagaga ttcattctta cgtactactg ttttagacat
    63481 ttttttcact cccttcaagt tcaatatcta tttcattcta cacgtaaaag gaataattgt
    63541 caagcaaaaa tgcggtttaa ttttgatttt ttcttccatt tatacaagag ttgaaagcgt
    63601 tcaatagaac attgcttttt tatttttcga gtaagctaag cgcttcagca tctgcgatga
    63661 tggttacatc agggtgattt tggaggctac ttgcaggtag gttctcagtc actgggccag
    63721 atactgttcc ggcaatggct tctgctttcg actcaccgta agcaaaaaga ataatagact
    63781 tggcatccaa aatgttttta atccccattg aaatagcttg ggttgggacg tcttcaatct
    63841 tggcaaagaa gcgtgcattg gcttcaatag tagactggtc aagttctact agatgcgttt
    63901 gactgtcaaa tggagtacca ggctcattaa agccgatatg cccattgcga ccgattccca
    63961 agatttggag gtcaactgga tggtcagcca aaatttggtt gtagcgttca acttcagctt
    64021 cagcattgtc cttaacacca cgaggcaaga aactttcttt aaatggtttt tggttgaaca
    64081 agttttcttg catgaagtaa cgataagact gtggattgtc cccatcaagg cccacatact
    64141 catcaaggtt gacactggtt agatttgaaa aatcaaggtt actctcaaca atttccttgt
    64201 aaaattcaag tgggctactt cctgtcgcaa gtcctagagt ttgagctcca ttagccaatt
    64261 tttccttcaa aatctcaaaa gcaacttttc caccttgaac ttggttttca actttaataa
    64321 ctttcatctt ttcatcctcc atttctatct atatttatta tatggtatag accaattttt
    64381 gtcaagtgaa aacgatttaa tttctaaaaa aagagcgtcc aaacttgaaa cgtgttataa
    64441 tggataggat tagaacttag aaagaatgaa cagatatatg aatacagctg attttgattt
    64501 ccacttgcca gaggaattaa ttgcccaaac gccccttgaa aaacgtgatg cctccaaact
    64561 cctcatcgtc aaccgtgaga caggagaaat gcaagataaa cacttccact ctattattaa
    64621 tatgctggaa cctggtgatg cccttgtcat gaacgacacc cgagttctcc ctgcccgcct
    64681 ctatggtcaa aaagtggaga caggaggtca tgtggaactt ctcctcctta agaacactag
    64741 tggagacgag tgggaagttc tggctaaacc tgccaaacgc ctcaaggtcg gtactcgtat
    64801 cagctttggt gatggtcgcc tcagcgctgt cgttacagaa gaattgaccc acgggggacg
    64861 cattgtccgc tttgaatacc aaagaatttt cctagaagtc ttggaaagtc tgggagaaat
    64921 gcctctgcca ccttatatcc acgaaaaatt agatgaccgt gaacgttatc aaaccgtcta
    64981 cgccaaggaa agcggctctg ctgcagcacc gactgctggt cttcacttca ccaaagaact
    65041 gctggcagaa atccaagcta agggtgttca tctagtctat ctgactctcc atgtcggact
    65101 cggaaccttt agacctgttt ctgtggataa tctggacgaa cacgaaatgc actcagagtt
    65161 ctatcaactt tctgaggaag ctgctgccac ccttcgctct gtcaaaaaaa atggtggtcg
    65221 tgtcatcgct gtcggaacca cttctatccg caccttggaa actattggtt ccaagtttga
    65281 tgggcaaatc caagcagatt ctggttggac caatatcttt atcaaacctg ggtatgagtg
    65341 gaaggtcgtg gatgccttct caaccaactt ccacctgcca aaatcaactc tggtcatgtt
    65401 ggtttctgcc tttgcaggcc gtgaattagt cttagatgca taccaccatg ccatccaaga
    65461 acactaccgc ttcttcagtt ttggtgacgc catgtttatt tattgagaaa gaatttctct
    65521 aaatcttcta ataccaataa atcgctaaga tattatttca aagaacatct acaattgaaa
    65581 ctctagctag ctgtagaaga ggcctagtac attgaaatta aaatgcttcc ccctagcttc
    65641 gaaaatattg ccatagattg cgttgactct ccaaattgat tcatctatat tttatttcag
    65701 cttcctatac tttcttcgct gtttgtaaat caaaatgcaa gacacatgag tagcaccata
    65761 tttgttactc ttatctgtcc tctcaagaga ctattatgag ttatttcaga atcattcact
    65821 actttgaccc tgactctcct tagtctcaaa atcaaagact tatactcttc aaaaatctct
    65881 tcaaaccgcg tcaacgtcac cttggattat atatgtgact gactttgtca gttctatcta
    65941 caacctcaaa gcagtacttt gagcaacctg cgactagttt tctagtttgc tctttgattt
    66001 tcattgagta ttaaacaaaa agtgaacaaa gctgaattct aatgtacaga agactaggct
    66061 tgttcacttt tttatagtcg ctataagatg accttatcta tagcttttta tatataatta
    66121 tatattcaga catactatta tcaattttgt ctcagggagg aatctgttaa cgcacccatt
    66181 caccattatc attgactcta tagccatcta tacttgtatt gaccgctaac tcacccgatg
    66241 catttacata ataccattta ccaccaactt ggaaccattg attaactttc atagaaccgt
    66301 tgctgttgag gtagtaccat gaaccattaa cttgtaccca acctgttgcc atggaaccat
    66361 cagtattata aaaataccac ataccatttt cttgtttcca gcctgttgtt ggagcaactg
    66421 ctttagctgg ttctactgct acatctgttc cttggttaga tgtaacagat acaggatacg
    66481 aaggaataga tgattgctca ggaacaacaa ctttttcagg ttctctcgtc cctctcctta
    66541 tacgtctttt taccatctct ttagtaattt gacgagaagt agtttcttca attgttccat
    66601 cacgttcatc tacagcatag attgtagtaa gagtaatttt accaatttct cctacttctt
    66661 gacctttatc aagagttggg tcatcgagat attctgtttc gattggaatt tcttggacaa
    66721 gaacttgggg cttggttcct tttttaacaa ctcttgtttg agagtcttct ttttgactta
    66781 aagtactctc agttacttgt ccactctttc catctacatc ataagttatc gttgtaactg
    66841 ttttcccatt ctttcctaga gtaatctctt gctcctgtcc tgcagaaagg tcattgtctg
    66901 cttcatattt agtagcacat ggaacaagaa cttcttcaac cttgctttta gctggaactt
    66961 tgataactgt atccgtggct tcttttctat caacagtaac ctgttcggta acatgaccag
    67021 tctctggatt aacatcgtag gtccttgtcg tagttacata gccatcctct ccatcaattg
    67081 taacaggatt ttcactacgg tcttttgttt catctttttc ataacgaatt cgcgtacttg
    67141 aaattttctt ggttactacc ttaggtttag tcgctacttt tacaataata tccccattgt
    67201 cagcgtcatc atactctatt ccctcttctt tatctctagt atcatctctg acatattgaa
    67261 tcccatcagc agcatgaaca aaacttgtat tcagattcct cctaaaaata aagttagccc
    67321 gattaccgca gaaccaaaaa tctttccgag tttacgtaat gcatagcgct tattggtatt
    67381 agattttgcc attacatcct acttctaaaa gttactactt ctagtatagc atcttttcta
    67441 tcaaacgtta aacagtatac tttatatatc aaatatactt agaatgatat attgattatt
    67501 gaactaacgc tttaactata tcgtaatcaa tctcatatat aaaggattgc agacatctta
    67561 tctaaataca tgctaatata tttagataca aacattccaa cttgataact ttcactcatc
    67621 tttcatcatt ccttatacaa ctatgcagta taaatagaat agttttctca tcagaatgag
    67681 actattttaa tattagatat tttgatagaa aaaacatgaa taaaattggt tgaatttaat
    67741 tccctaactc gatagaggat tctattttaa atttaacaac agctaggatt acactataaa
    67801 aagtacatta ccacctgttc ggctggagaa tctagtcgat tagctccctc ttagttacaa
    67861 gcttaaagcg attttttaac taatactaaa ccagattaaa gaaggaacta gaacatctgt
    67921 cttgtactaa tcaatatgct attttaaagt tgcaaataaa cttggaatgc taattattat
    67981 atttacaata aatagttgac ttcgatagaa acagaaaata gaattcaaca ttcttcccta
    68041 cttataccat aataaataag atccgcaaga tagccttttc tctctacacc attaacaatg
    68101 gtttgtagat aggacattcc agccttttcc atgacacgac ctgaagctgg gttgagactg
    68161 gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa aacaaaagtc caagatagct
    68221 ttcaaagtct ctgtcatcat accatttccc cagtaagcct tgcctaacac atagccaatt
    68281 tcacagctta aatcagcctc gtctatctta acaatgctga tatctcctat cacttgctct
    68341 gggttttctt ttagacaaat ggcccattta taatagttga gattagtata ggaagcaacc
    68401 caattgcaaa tcgagtttcg agtgatttcg acatcaggat ggggatccca ggtaacatag
    68461 gtcagattct cagcggatga agcccaattt tgaaacatgg cttctgcatc actctccaca
    68521 aatcttctta aaatcaaacg ttctgtctgt aatatttgcg taccgataga tttcatgatg
    68581 ctacctcact tccttatttc tatgctcgta gtaaaaaggc tcaactcagt aacagctaga
    68641 aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc tggtttgaaa tgcgctctag
    68701 caatcttttt caaacctagt catcgttgca ggggtaagac gatgaaatcg aactcttcga
    68761 gttaccgaat ctgcctcatt ttcttatttc aagatgagag gctgaaaacc tccagtggag
    68821 gtttttcttg ctttttaatt tcagggcaag aagctaaaaa ggtcccccgg accttcttcg
    68881 ctttctcatt tctaggctca gggtaaaaac ctccaatgga ggtttttact cccaaaagtc
    68941 atcaaatacg gtgatgggta agtggcgttt gtgttggcct ttgtgccacc agttttcaat
    69001 ggtcgcttga gcttctgggc tgattgtttt gccttctagg taatcgtcaa tctctgcata
    69061 ggtgactcca agtgcgactt cgtcagctag gcctggtttg tcttcttcta ggtctgccgt
    69121 tgggattttt tcataaaggg ctgggtctgc accaagttcc tgtaagagtt gttttccttg
    69181 acgtttattg aggcggtaaa gagggagaat atccgcacca ccgtcaccaa acttggtaaa
    69241 aaagcctgtg atattttccg cggcgtggtc tgttccaatg accgctccgc tatgggaacc
    69301 agcaagggca tactgagcaa tcatacggca acgtgccttg atattcccct tgttgaagtc
    69361 tgaaacagga ctacctgtcg cttcaactgc agctgtcatg gcatcagctg attccttgat
    69421 attcacaacc aagctgacat ctggctggat gaaggctagg gctttttgag catctgcttc
    69481 atcagcttgc actccgtatg gcaggcggac aacgataaat ttgtagctgt cgtctcccgt
    69541 ttcagctcgc agttcttcca tagctaattg cgccaaacgc cctgccaagg ttgagtcttg
    69601 tcccccagaa atccctagta caaaggtttt taggaaggga tgttttttca gatatctttt
    69661 taagaaatca atagaacgac ggatttcttc ctgggcatca atcactggtt tgacacccag
    69721 ctcttggata atcgtttctt gcaaactcat tcttcttctc cttcaccaag ggcttccttg
    69781 cgcatcttat caatcaagtc catcttatct tgccatacat cacgcgccaa atccactgga
    69841 tagtgctgcg gattgagcac acgcttatac tcatcccaca acttgtcaaa ttccttacgg
    69901 gcataatcct gaatgtcagt caaactaggc aagttgtaaa ctaatattcc ttctttgaag
    69961 atatccacca agagaggaac ggcatcaaaa ttacgaaccg tcttcttgat gtatgtatag
    70021 gtcggatgga acatcttgat ttctgtcatg tcgctaatat ccacaccatc ataagtgata
    70081 tagtcgcctt ctgacttgcc tttttcacga ctggtaatgc gccacacctg cttcttacct
    70141 ggcgtagaaa ctttttcagc attattagac agcttaatcg tattgcgcat ctgaccagtt
    70201 tcatcttcga ttgcaacaat cttgtaaact gcaccaagag ctggctggtc ataagctgta
    70261 atcagcttgg tacccacgcc ccagacatca atcttggcct tttgcatctt gagattgagg
    70321 atagtatttt cgtccaaatc attagaagca taaatcttag cctctgtaaa tccagcctcg
    70381 tccagttgct gacggacttt cttagaaatg taggcaatat ccccagagtc aatccgcaca
    70441 cccataaagt taatctgatc acccagctca cacgccacct gaatggcagc tggtacaccg
    70501 atgcgaaagg tgtcataggt atccacaaga aagacacaat ttttgtgggt ctcagcgtaa
    70561 gccttgaaag cttcatagtc attgccataa acctgtacca aggcatgggc atgggttccc
    70621 aaaacaggaa tgtcaaagag cttacccgca cgcacgttgc tggttccatt ggccccacca
    70681 atcaccgctg cgcgtgttcc ccagatggcc gcatccattt cttgagcccg acgtgtccca
    70741 aactccatca agggttcatc ttcgataacc gaacgaatac gagctgcctt cgtcgccacc
    70801 aaggtctggt agttgacgat gttcaaaaga gccgtttcga ccaactgaca ttgggctaga
    70861 ggtccttcca cctgcacaat cggttcatta gcaaaaacca aatccccttc ttgggcagaa
    70921 cgaacggtca actccaactt gaaattgcga aggtaatcca agaacgcccc atgataacca
    70981 agcgactcca aataggctat atcactatct gaaaaacgca agtcttcaag atagttcaca
    71041 attctttcca aacctgcaaa aaccgcatag ccgttcttaa aaggctgttg gcggaaatac
    71101 acctcaaaga ccgccttctt attgtgaatc ccttggtcaa agtaaacctg catcatgttg
    71161 atctggtaca agtccgtgtg caatgtcaaa ctatcatctg gatacatact tttcctactt
    71221 ccttagctag aaacccatga aaattttcaa gaactttcat gtattccaat aaattagtac
    71281 tattatatca cattttagct ggattgagaa aagagtaaca agctattctc cactctccaa
    71341 ttcatccata tcttgttcaa attttttctg agcccattcg ccatagctct taagaccaag
    71401 attgccaata aagacccacg gaaggtaaat gacataagta atgacccaag cagacaggta
    71461 tttaaaattc aaaggattgt gctgataaat ttctatgttg aattgataat tctgcaacat
    71521 caaaagagcc gtaatagcca aggttaggaa aaaacaaccc aaaatcgtaa aatgaaaacg
    71581 actatagtag gtcactccca gataacgggc acgattgaaa aagtaaaatg tccctatgat
    71641 gataacgatt agcagcatat tagaattaaa aaggcttggt gctaatactg aaatgatata
    71701 agataggagc gacaaagcga tgcagatata gaaactttca gagcccgctt tattgaacag
    71761 ttgttcttct ctttcgtcta gtaattgata ataataaaat ctatttttca tcttcttcct
    71821 cccaaaatag ttggtctagg gttttcccta aacatctgca aatggactgg cagagcgaga
    71881 gactgggatt gtatttcccc gcctctatca aaccaatagt ctggcgcgtc accccgacag
    71941 catctgctag ttgaccttga gttaaatcaa gctctacccg agctaatttt aattttaaat
    72001 ttttaaccac cttcgtcctc cttataattt taatattcat ctactcttaa aaaattccaa
    72061 actaacacaa gctgtcagct atttattata accccattaa tttgcactcc agtattatct
    72121 tcagccgaaa atcagtattt taggttgttt gaaataaact tcctagttta ctcttttatt
    72181 tttatttagt attagcttta gtaggagctt ttaaacgagt ttttattgct tatatttctt
    72241 gtttagttta gttggtttca tatcactatt atataatgct tttgaaaata agcctagtat
    72301 aagtcaaaaa cgtgttgaat agtgaaagca ggagcatacc aagatgactg atttttttac
    72361 tgtattttag gtatgcaaaa taatactaaa tgaaactaaa atgaatactt cttgcttttc
    72421 ttgagagtga aaaagtacaa taaaatgatt gtagtgatta gcacaagata ctgactaata
    72481 gacatcgtat ttgaagtcac aaatacaggt aaagaataaa aaggaagaag ttcaattgct
    72541 ttgataaaca aatcattact agtattcatc atcatcgtat ttaatatatt agggataaag
    72601 agtagtaaag ctactaaaat accaaatacc aagccacttt tcaatttgta taaatagaaa
    72661 atgtaagata atagaaaata aaacaggact aacaaaattg tattgactac aatagctact
    72721 ataaaatcta atcctaaatc acctggaata cccaatttac ttactatgac tagtaacaca
    72781 atgccattca aagcataaat aatggaaact gagatggcat atagaaaatt agacaagacg
    72841 taaatcatcc gattcttctg ttgattataa aacaaactta ccgtattgtg ggaaaaatct
    72901 ctactaatga ctcgattagc atgtataaca gccattaaca taccgagcat agcataaaag
    72961 tttgaaatat gcttaatacc aagcgatgtc ccttgagtct ttagaataaa gaatgtaacc
    73021 aatatcggcg gtataaacga gataagcaaa ccgagatata ttacacctga tgaatataaa
    73081 tttcttatat tttccttaag aaaattaaat ttatttaatt tcatgattat aaccctcctt
    73141 tattttgaac gatttagata aatatcttta agcgtctctt ttttagtttt aaaatcaact
    73201 actttaatag agttttcgtt aaaaaattta aaaagctcac tactttgaat attcccagac
    73261 atagtaattc tcagtccctc ttcctgaaca atatccccaa attcttgttt ggtaatgaaa
    73321 atgtctctat ctgtagctga tgaaaaagct atctcaaaca agaaattatg actatctttt
    73381 cctacttttt gaaatgtcaa aagcccgctc tccaagaaaa gaaccctctc acaaatttct
    73441 tcaatatctt ctaatttatg actcgatatt aaaattccca cattttcatg taaagctaaa
    73501 ttttttagaa ccgctaaaac tatttgtgat gattcaatat ctaaaccatt agtcggttca
    73561 tctaaaatca atatatcaag ttctgtaacg agggttaaaa gcaaagctaa tttttgtttt
    73621 gtacccaaag aataggtctt tactttttta ttaatagact gagtcaaatc taactcttgg
    73681 atcaaacttc taaatctttc ttgattgtag tcaacaccat ataaatttga caaatatttt
    73741 aaattctcta aacctgtttt agataaaaat aattttggtt cttcgattaa atacccaaca
    73801 ttatcactgc ttataatatt acctgaagtc ggttgattat tctgaacaag aattttcatc
    73861 aacgtactct taccaactcc atttctccct acttgaccaa caatttcacc cttgttaagt
    73921 gcaaaattta tatctttgag aataattgaa tgaccataat gcttacttac attttttatt
    73981 cctccattaa tattattggt tttctctttg attctcatta attttaaaaa gttgcgcctc
    74041 tttttaacaa tattatatca tatatctaac ttaatgcaat atataaatgt cattttgtga
    74101 aattttatta acaaaaaact ctatacaaca aaataataga gagttttctg cttattaatt
    74161 tttttcaaaa tatctaagac atcgcttctt tgtttaattt gataggcttt gatacctaag
    74221 ctccgacttt atcacttaaa aaataaaaaa gacagctaat ctcttgcgca tcaggggatt
    74281 tcgccattct ttaatctcgt ttaagtgttg tatatggagc tttgcataat tttttaaaac
    74341 taaacaacta cattaagctc gaactgtgac gctggttcca tcttccttat aaagattgat
    74401 aagcccctct ttaagagctc gaaccatgtc tccagcttga acaggttgtg ggactttaat
    74461 agtcaatagt tccattggat ttggagcgcg gtcgatttta tttcctttgg catcatgcaa
    74521 atcttcaata taggtttcaa aatgacggaa acctggacca taaaactcaa cttggtcccc
    74581 ttcgttaatg acgttccgtt gacgaatggt tgctgtttgt gtcgcatcat cataagaaac
    74641 cacttcagcg acaaacttgt actcaggaat tttacgacga gcaccaaaca actgctcatt
    74701 ttcagatggt gtaccatagt aaaatcctgt aaccagttca cgttgggcaa ccttccacat
    74761 ctcgtccacc aagtcttgtt tgatagcttc aaacttttca gaactttcaa gataggcatc
    74821 cacagccgcc ttgtagcagt tggttactgt tgatacgtag tgaatagact tcatacgtcc
    74881 ttcgattttt agactgtcca caccattttc aatcatatct ggaatgtggt caatcataga
    74941 catgtcaacg gctgacattg aaaattcttc tggaatctca ccctgcaaac tcttacgttc
    75001 tttcccaaat ggcatatcgt aaaggtcgta tttccaacgg catgactgag aacatccacc
    75061 acggttggca tcacgcatac tctagacgga ttgttttgac aattctaacc ttttagactt
    75121 tgcataataa ctgttaaaca gtcgaaaatt accccagttt taacaagtag tcaaaatacc
    75181 agataaagga aaaaagtctt taaaatctta aaaacgcata gtatcaggta ttgaacaatc
    75241 ttgatattat gcgttttatt gtgggaagat ttacttcatt ttctcttgga attgagtttt
    75301 ctcctacttc aaaactagat gatttgctat ttaaaatagc gttccttatg attttggcaa
    75361 cctggattaa agcgagaaaa acaaaagggg caacttaaac tttctttata ttgcttatat
    75421 gttagtagtt ttagacaaac accacataaa ataggcttat cctgtatcaa agataaggga
    75481 tacggctcaa aagggtgatt ttctaatgaa tcatgacacc gataacaagc atagtacttt
    75541 ttacaatcat agcattgtaa agcaataata tccaacttgc tatggtaatg aatgcatctt
    75601 gtttgcttat ccactaagaa accctgtgcc tctatcattt ccttttcctt tcttaagctc
    75661 gaactgtgac gctggttcca tcttccttat aaaaattgat gagtccttct tttaatgcac
    75721 gaaccatgtc tcctgattga acgggttgtg ggactttaat agtcaatagt tccattggat
    75781 ttggagcgcg gtcgatttta ttgcctttgg catcatgcaa atcttcaata taggtttcaa
    75841 aatgacggaa acctggacca taaaactcaa cttggtcccc ttcgttaatg acgtttcgtt
    75901 gacgaatagt tgctgtttgt gccgcatcat cataagaaac cacttcagcg acaaacttgt
    75961 actcaggaat tttacggcga gcaccaaaca actgctcatt ttcagatggt ataccgtagt
    76021 agaaacctgt tgccaattca cgttgggcaa ccttccacat ctcgtccacc aagtcttgtt
    76081 tgatagcttc aaacttttca ggactttcaa gataggcatc cacagccgcc ttgtagcagt
    76141 tggttactgt tgatacgtag tgaatagact tcatacgtcc ttcgattttt agactgtcca
    76201 caccattttc aatcatatct ggaatgtggt caatcataga catatcaacg gctgacattg
    76261 aaaattcttc tggaatctca cccttcaaac tcttacgttc tttcccaaat ggcatatcgt
    76321 aaaggtcgta tttccaacgg catgactgag aacatccacc acggttggca tcacgcatac
    76381 tcatgtggtt tgaaagagta caacgtccag agtatgaaat acacatagct ccatggacaa
    76441 aggcttcaat ttcaacatct gtacgtttgc ggatttcagc taattcttcc attgaaacct
    76501 cacgcgctaa aacgacacga gtcaagccta gctctttcca gaactcaagg gtttcatagt
    76561 tagtggcact ggcttgggta gaaaggtgga tttcaaggcc tggtgcttca gtcgctgcaa
    76621 tcataatcaa ggctgggtca gatacgataa ctgctgcaat cccaatatca cgcagtttac
    76681 ggaaccactc accagcacca gcttcatttc cttcgtgcat aaccatatta gccgctacat
    76741 agaccttggc accatacttg gccgcaaact gcacgccttc ttccatctgt tcgaaagtaa
    76801 agtttccggc acggctacga agaccatagg cctgaccacc gataaagaca gcatctgctc
    76861 catactgaac agctaccttt agcttctcta aagtccctgc aggtgataaa acctcaggac
    76921 gttttaatgt ttttgtcatg atttctccta tttgcaatat aaaagtttga catttttcct
    76981 tctcatttta tagtaaataa aggataaaat caagcctaga cggattgttt tgacaattct
    77041 aatcttttag actttgcata ataactgtta aacagtcgaa aattacccca gttttaacaa
    77101 gtagtcaaaa agtctagaaa agtaaaaacc agtatccaaa gatactgact cgtaaaaata
    77161 cataaattag tccttagatg actactccca ctctgttgct cctataatgg aaaaggattg
    77221 atacagtcta gaatatcgct tttttattta ttattctgat ataaaactgt tagaattgat
    77281 tttttgtttt atacccaaat atgaatagag acgtagctaa taagttgaat aacatatttg
    77341 gaaaaatgag aaatagcaat attactagaa cttttagaaa caatcaatat ttaaaaagaa
    77401 aaaagctcaa agaatttatt aaaccatgtt ataatagata tagctataat tttatttata
    77461 acaagaggat agaaatgacc gaattagaaa gaaaaaatcg aaaaattagc taagaaatat
    77521 tctaataact taaacatcaa agttcaagag agagttcgtg aaatggcaaa tgataataag
    77581 agccattatt tgatatacag agttttaggt atttcatttg aagaaggaga aaatatcgat
    77641 ttgtatcaaa ataaaggtcg ttttttatac aaatatgctg gttcattttt agaagaagct
    77701 gcagtactat cctttaacga aaaatttggt acagaaaata cttaaaaagt taacattcct
    77761 aattctgaaa gtacaaaacc taagactttt gaaattgatt gtttagtcgg agaaaaacac
    77821 gcatacgaaa taaaatggtg ggatgcaact acagatggag accatataac taaagaacac
    77881 actagaataa aagttattca taacaaagga tatataccaa ttcggttaat gttctactat
    77941 ccaaatagaa ctcaagctat aaaaattcag caaactttag aaacattgta taacggtatt
    78001 ggagggaaat attattatgg agattctgcc tgggaacatt taagagcagt gaccggtatt
    78061 gatttactta gtattctaac agatattgca aataaaaaaa caggggtaaa atcaaaatga
    78121 cagtattaaa aggagataac ttagaaatat taaaaactat tgaatcctca agtattgatt
    78181 taatctatat ggaccctcct ttctttacac agaaaaccca aaaattatct aataacaaaa
    78241 atattatgta ttcattcgaa gatacgtgga cttcgattga ggattacaaa gaatttttgt
    78301 ctgtaagatt agaagaatgc aaaagagtgc taaaaaatag tggcagtatt ttcgttcatt
    78361 gtgataaaat tgcaaatcat catattagat taattttaga taatatcttt ggagcagata
    78421 tgtttcaaag cgaaattata tggaactata aacggtggtc taattcaaaa aagggattat
    78481 tgaacaatca tcaaaacatt tacttttatt caaagtcaaa agattttaaa tttaatacaa
    78541 tttttacaga gtattcttct actacaaata tcgaccaaat actagtggaa cgaaaacgag
    78601 atgaaaactc taaaactata tataaagttg ataataatgg taactatatt ctagcaaaag
    78661 agaaaaatgg agttcccctt tcagatgttt ggaatatacc atttcttaat ccaaaagcta
    78721 aagaaagagt aggttatcct acacaaaaac ctattctgtt attagaacaa attataaaga
    78781 ttgctactga taaaaatgat atagttttag acccgttctg tggaagtgga actactttag
    78841 tagcctccaa gattttgaat agaaattata tggggattga tttatctgag gaagctatca
    78901 atataactca gcaacgtctg gaaaatgtta taaaaacaag ttcaaattta ttgaataaag
    78961 gaatcgaagc atatagaacc aaaactgagg aagaggaaaa cattcttaaa ttattacagg
    79021 caaaaattgt tcaaagaaat aaaggaattg atggtttttt acctaaacat tttcaaaaaa
    79081 aaccgatacc tataaaaatt caaaaaaata atgaatgtct gaatgagagt atctctttat
    79141 tacagaatgc tataaactcc aaaaaacttg attttggagt agttataaaa actcattcag
    79201 ataatttatt atttgatttt gatacgattc ctgaaaatat aatagtagtt gaccattttg
    79261 aacttacaat cgaaaaatgg ttaagtaaaa gtcaacagtt actatagttt gcaaattatt
    79321 tacagaaaga acaaaaaatg ctctgaaaca ctgatttcaa agcatttttt gttagtttaa
    79381 aattactccc attcttcttt tccaaacgta caatatatcc aaaaccattc aaaatactag
    79441 attctatttt ttataatatt actaaatcca cctaattata ggacgttttc agatttttag
    79501 tcccgtccca gtcccagtac cggagaaata ttgttttaat ataatatctc tttttgtctt
    79561 ctaagctctt aaaagcaaaa gaacaagtaa agagtcaaga caaggataaa aagtccatat
    79621 tagggcaaat aaaaagcttt aagacagatg acaaatttaa gtcaaataag aaagaccata
    79681 gcaaaggtgc agagagataa atattggcgg tcttcggact gcctttattt ttttatccat
    79741 ttttcaaatc aaatttattc agactataca tgcacatata cacttaaatt aatataaaaa
    79801 catggcttgt aaaaaattac tttaatcaca ataatcgcat ttaaaattgt gatgtttgca
    79861 agctaaatta cggacttcac ttggaagttt tcccttgtat cttttataat agatagaaaa
    79921 tttgctggca gatgaatatc caacagattc tgctatctct tttataggta gttcagtgtt
    79981 taaaagaaga gtttcagcta cattcattct ttttctttga gtgtactctg taatgctttg
    80041 acaatatttt tccttaaata aattttttaa tttagtacca ctcattttag atattttttc
    80101 aagcgtgcct tgatttacat tcgttgcaaa atgatcatct aagaatcttg ctacatcttc
    80161 aagtgcttta tcatcatcaa tttcaatttt atattttttt ctatttaagt atgtgtcaat
    80221 tactatactt atccattcat ttgcctttgc tttaaagaaa aaatcagcgg caggagcgtc
    80281 catcttacaa tttaatattt ccattgccac tctttctaag gcctttgtaa gtattatttg
    80341 attcggttga agcaaggttg aataaaaaga ttctggatta atgttaatag atgctaaatg
    80401 tttttctatt agctcttttt taaaaccaat ggaaacagca agataacaac aattctcgtg
    80461 taataaaaaa acaaaatcat cttttatatt atcaaaatca aaagtacata aagagtttgc
    80521 ggtaatagtt tgatacggat taaacttttc tccgtttgca ctgacaatgt aacttgaata
    80581 aattgaaaca tagtctgaca tactataagt gctattttga actacttcct ctttgatata
    80641 aaaatcatgt atatcgataa tgaagctgcc tccttcataa aaccaatata ggccttctgc
    80701 ataagttgaa ttctcttttt tccaacaaaa tgtatgacct gcacttgaat acttctcatt
    80761 gtttttacat tcatctactt tcatataatc ttttacaaaa tcataatatg acataacaca
    80821 ctatcccttt tagacaatat tccaattagc cttattaatt caaaactatt gtattagtaa
    80881 ttataacaga t
//
LOCUS       DAVHSI010000004        77598 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.004, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000004 DAVHSI010000000
VERSION     DAVHSI010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.004"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            1..639
                     /locus_tag="VVR21_000251"
                     /pseudo
     CDS             1..639
                     /locus_tag="VVR21_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(756..1103)
                     /locus_tag="VVR21_000252"
     CDS             complement(756..1103)
                     /locus_tag="VVR21_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6054207.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKFLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1214..2989)
                     /gene="spxB"
                     /locus_tag="VVR21_000253"
     CDS             complement(1214..2989)
                     /gene="spxB"
                     /locus_tag="VVR21_000253"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU6054208.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3196..5439)
                     /locus_tag="VVR21_000254"
     CDS             complement(3196..5439)
                     /locus_tag="VVR21_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU6054209.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5449..5820)
                     /locus_tag="VVR21_000255"
     CDS             complement(5449..5820)
                     /locus_tag="VVR21_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU6054210.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5831..6226)
                     /locus_tag="VVR21_000256"
     CDS             complement(5831..6226)
                     /locus_tag="VVR21_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU6054211.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6410..6508
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6592..7383
                     /gene="thiD"
                     /locus_tag="VVR21_000257"
     CDS             6592..7383
                     /gene="thiD"
                     /locus_tag="VVR21_000257"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6054212.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7593..8225)
                     /locus_tag="VVR21_000258"
     CDS             complement(7593..8225)
                     /locus_tag="VVR21_000258"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6054213.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8218..9021)
                     /locus_tag="VVR21_000259"
                     /pseudo
     CDS             complement(8218..9021)
                     /locus_tag="VVR21_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
     gene            complement(9021..9545)
                     /gene="thiW"
                     /locus_tag="VVR21_000260"
     CDS             complement(9021..9545)
                     /gene="thiW"
                     /locus_tag="VVR21_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU6054214.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9550..10242)
                     /gene="tenA"
                     /locus_tag="VVR21_000261"
     CDS             complement(9550..10242)
                     /gene="tenA"
                     /locus_tag="VVR21_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU6054215.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10253..10903)
                     /locus_tag="VVR21_000262"
     CDS             complement(10253..10903)
                     /locus_tag="VVR21_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU6054216.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10905..12290)
                     /locus_tag="VVR21_000263"
     CDS             complement(10905..12290)
                     /locus_tag="VVR21_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054217.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNLNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDYMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12291..12851)
                     /locus_tag="VVR21_000264"
     CDS             complement(12291..12851)
                     /locus_tag="VVR21_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6054218.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13114..13202)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13411..14040)
                     /locus_tag="VVR21_000265"
     CDS             complement(13411..14040)
                     /locus_tag="VVR21_000265"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU6054219.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14042..14824)
                     /gene="thiM"
                     /locus_tag="VVR21_000266"
     CDS             complement(14042..14824)
                     /gene="thiM"
                     /locus_tag="VVR21_000266"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU6054220.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            14915..15001
                     /locus_tag="VVR21_000267"
                     /pseudo
     CDS             14915..15001
                     /locus_tag="VVR21_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(15151..15819)
                     /locus_tag="VVR21_000268"
     CDS             complement(15151..15819)
                     /locus_tag="VVR21_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU6054221.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(16034..16122)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16374..17510)
                     /gene="lctO"
                     /locus_tag="VVR21_000269"
     CDS             complement(16374..17510)
                     /gene="lctO"
                     /locus_tag="VVR21_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU6054222.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18134..19624)
                     /gene="lysS"
                     /locus_tag="VVR21_000270"
     CDS             complement(18134..19624)
                     /gene="lysS"
                     /locus_tag="VVR21_000270"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU6054223.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19752..19898)
                     /locus_tag="VVR21_000271"
     CDS             complement(19752..19898)
                     /locus_tag="VVR21_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU6054224.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            20114..20794
                     /locus_tag="VVR21_000272"
     CDS             20114..20794
                     /locus_tag="VVR21_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6054225.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDFIGLYYETDIALAMLVVAYLIILLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            20754..21431
                     /locus_tag="VVR21_000273"
     CDS             20754..21431
                     /locus_tag="VVR21_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6054226.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVILIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            21432..22189
                     /locus_tag="VVR21_000274"
                     /pseudo
     CDS             21432..22189
                     /locus_tag="VVR21_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22201..23061
                     /locus_tag="VVR21_000275"
     CDS             22201..23061
                     /locus_tag="VVR21_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6054227.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGPSSGKTTAKARTID
                     ENKKSGELRIAVFGDKKPFDYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(23141..23788)
                     /locus_tag="VVR21_000276"
     CDS             complement(23141..23788)
                     /locus_tag="VVR21_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054228.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPTNLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23785..24483)
                     /locus_tag="VVR21_000277"
     CDS             complement(23785..24483)
                     /locus_tag="VVR21_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054229.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(24493..25245)
                     /locus_tag="VVR21_000278"
     CDS             complement(24493..25245)
                     /locus_tag="VVR21_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054230.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(25245..26009)
                     /locus_tag="VVR21_000279"
     CDS             complement(25245..26009)
                     /locus_tag="VVR21_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054231.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYGLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(26105..26508)
                     /locus_tag="VVR21_000280"
                     /pseudo
     CDS             complement(26105..26508)
                     /locus_tag="VVR21_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26688..27320)
                     /locus_tag="VVR21_000281"
     CDS             complement(26688..27320)
                     /locus_tag="VVR21_000281"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU6054232.1"
                     /translation="MTLAKDIASHLLKIQSVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(27354..28055)
                     /gene="pyrF"
                     /locus_tag="VVR21_000282"
     CDS             complement(27354..28055)
                     /gene="pyrF"
                     /locus_tag="VVR21_000282"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU6054233.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKALGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNIHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(28288..29487)
                     /gene="divIB"
                     /locus_tag="VVR21_000283"
     CDS             complement(28288..29487)
                     /gene="divIB"
                     /locus_tag="VVR21_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU6054234.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVELAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29497..30555)
                     /locus_tag="VVR21_000284"
     CDS             complement(29497..30555)
                     /locus_tag="VVR21_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU6054235.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     TELKSLADFYQLLKKDLS"
     gene            complement(30557..31909)
                     /locus_tag="VVR21_000285"
     CDS             complement(30557..31909)
                     /locus_tag="VVR21_000285"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU6054236.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(32013..32654)
                     /locus_tag="VVR21_000286"
     CDS             complement(32013..32654)
                     /locus_tag="VVR21_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054237.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32656..34677)
                     /locus_tag="VVR21_000287"
     CDS             complement(32656..34677)
                     /locus_tag="VVR21_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6054238.1"
                     /translation="MKKLFILLSTFFLSFFFAWIIVLRAPQYLYASYDSVTLLRVKKE
                     AQEPTREVFEQELEKFVNSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKQFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKAIADRKTPPYSLAFRMLLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWHDRVDYYQISFGL
                     GDRVNDTENQNKWYEFSKEAVEKEQALFVKENLIHFANPQGKNENGETLDTYSPDANV
                     LYVSPSYLDKENVAVNDETRQKLAHLQKGEFGLLLPESLRSQEAELKKVFEERLNYYG
                     KSSEDKDAPLEYEMRAIVSYLPTGQKRFVYNNGESPVSIQYLTDPILVVFTPTSTGDS
                     FISKYVWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASFFILSSRDLVIGLLTLFVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(34748..35047)
                     /locus_tag="VVR21_000288"
     CDS             complement(34748..35047)
                     /locus_tag="VVR21_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6054239.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSVVSKWDSHSDKGSAPAGKTSEAWIWTKFGEQVSFYYDYD"
     gene            complement(35410..35664)
                     /locus_tag="VVR21_000289"
     CDS             complement(35410..35664)
                     /locus_tag="VVR21_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU6054240.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35684..37525)
                     /gene="typA"
                     /locus_tag="VVR21_000290"
     CDS             complement(35684..37525)
                     /gene="typA"
                     /locus_tag="VVR21_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU6054241.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37687..38412
                     /locus_tag="VVR21_000291"
     CDS             37687..38412
                     /locus_tag="VVR21_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEU6054242.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(38452..38679)
                     /locus_tag="VVR21_000292"
     CDS             complement(38452..38679)
                     /locus_tag="VVR21_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054243.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38768..39148)
                     /locus_tag="VVR21_000293"
     CDS             complement(38768..39148)
                     /locus_tag="VVR21_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6054244.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(39148..39417)
                     /locus_tag="VVR21_000294"
     CDS             complement(39148..39417)
                     /locus_tag="VVR21_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU6054245.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39481..40389
                     /locus_tag="VVR21_000295"
     CDS             39481..40389
                     /locus_tag="VVR21_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6054246.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(40443..41198)
                     /locus_tag="VVR21_000296"
     CDS             complement(40443..41198)
                     /locus_tag="VVR21_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU6054247.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(41219..42148)
                     /locus_tag="VVR21_000297"
     CDS             complement(41219..42148)
                     /locus_tag="VVR21_000297"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU6054248.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(42163..42786)
                     /locus_tag="VVR21_000298"
     CDS             complement(42163..42786)
                     /locus_tag="VVR21_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU6054249.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42779..44017)
                     /gene="hflX"
                     /locus_tag="VVR21_000299"
     CDS             complement(42779..44017)
                     /gene="hflX"
                     /locus_tag="VVR21_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU6054250.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFMPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(44010..44894)
                     /gene="miaA"
                     /locus_tag="VVR21_000300"
     CDS             complement(44010..44894)
                     /gene="miaA"
                     /locus_tag="VVR21_000300"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU6054251.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            45015..45185
                     /locus_tag="VVR21_000301"
     CDS             45015..45185
                     /locus_tag="VVR21_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU6054252.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(45233..46072)
                     /locus_tag="VVR21_000302"
     CDS             complement(45233..46072)
                     /locus_tag="VVR21_000302"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU6054253.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(46169..47128)
                     /locus_tag="VVR21_000303"
     CDS             complement(46169..47128)
                     /locus_tag="VVR21_000303"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU6054254.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(47255..48253)
                     /locus_tag="VVR21_000304"
     CDS             complement(47255..48253)
                     /locus_tag="VVR21_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU6054255.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSNGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(48303..48920)
                     /locus_tag="VVR21_000305"
     CDS             complement(48303..48920)
                     /locus_tag="VVR21_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6054256.1"
                     /translation="MKLIFLHGLEQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48921..50642)
                     /gene="pabB"
                     /locus_tag="VVR21_000306"
     CDS             complement(48921..50642)
                     /gene="pabB"
                     /locus_tag="VVR21_000306"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU6054257.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50711..56398)
                     /locus_tag="VVR21_000307"
     CDS             complement(50711..56398)
                     /locus_tag="VVR21_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6054258.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSITNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKETSQQENPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVETDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSAAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKREAFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKSLLKNTDGFSGDLFTAPQA"
     gene            complement(56420..56983)
                     /locus_tag="VVR21_000308"
     CDS             complement(56420..56983)
                     /locus_tag="VVR21_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU6054259.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILSSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(57099..58790)
                     /locus_tag="VVR21_000309"
     CDS             complement(57099..58790)
                     /locus_tag="VVR21_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6054260.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VTFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58787..59524)
                     /locus_tag="VVR21_000310"
     CDS             complement(58787..59524)
                     /locus_tag="VVR21_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6054261.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(59792..60904)
                     /gene="msrB"
                     /locus_tag="VVR21_000311"
     CDS             complement(59792..60904)
                     /gene="msrB"
                     /locus_tag="VVR21_000311"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU6054262.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(60915..61481)
                     /locus_tag="VVR21_000312"
     CDS             complement(60915..61481)
                     /locus_tag="VVR21_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU6054263.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(61501..62211)
                     /gene="ccdA2"
                     /locus_tag="VVR21_000313"
     CDS             complement(61501..62211)
                     /gene="ccdA2"
                     /locus_tag="VVR21_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6054264.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(62422..63282)
                     /locus_tag="VVR21_000314"
     CDS             complement(62422..63282)
                     /locus_tag="VVR21_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU6054265.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(63461..65515)
                     /locus_tag="VVR21_000315"
     CDS             complement(63461..65515)
                     /locus_tag="VVR21_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU6054266.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIVLTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(65527..65781)
                     /locus_tag="VVR21_000316"
     CDS             complement(65527..65781)
                     /locus_tag="VVR21_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054267.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQVHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(65774..66331)
                     /locus_tag="VVR21_000317"
                     /pseudo
     CDS             complement(65774..66331)
                     /locus_tag="VVR21_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(66315..67262)
                     /locus_tag="VVR21_000318"
                     /pseudo
     CDS             complement(66315..67262)
                     /locus_tag="VVR21_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241739.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            67373..67732
                     /locus_tag="VVR21_000319"
     CDS             67373..67732
                     /locus_tag="VVR21_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU6054268.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            67942..68798
                     /locus_tag="VVR21_000320"
                     /pseudo
     CDS             67942..68798
                     /locus_tag="VVR21_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125496.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(69046..75732)
                     /locus_tag="VVR21_000321"
     CDS             complement(69046..75732)
                     /locus_tag="VVR21_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU6054269.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKIF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPSSEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQVGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEIAEEDKVKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTIRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(75892..75969)
                     /locus_tag="VVR21_000322"
                     /pseudo
     CDS             complement(75892..75969)
                     /locus_tag="VVR21_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(75992..77467)
                     /locus_tag="VVR21_000323"
     CDS             complement(75992..77467)
                     /locus_tag="VVR21_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU6054270.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            complement(77515..>77598)
                     /locus_tag="VVR21_000324"
     CDS             complement(77515..>77598)
                     /locus_tag="VVR21_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6054271.1"
                     /translation="PILFRIPAMSAPVFDNIEAAIKEHGLS"
BASE COUNT        22782 a        17064 c        14259 g        23493 t
ORIGIN      
        1 ttacgccacg tccagaacat cctaagaaag cagacgctca aaccattgtc gcgtctaaaa
       61 ataaaatctc aattcaagaa gaaaagaaag cgatttaaaa ccagtagacg ttttcgtaag
      121 gttcgcttga tgtaccaaga tgaggctggt ttcggtagaa tcagtaaact gggatcttgt
      181 tggtctccaa taggagtagg tccacatatc catagtcact atatacgaga atttcgctat
      241 tgttatggag ctgttgatgc ctatacaggc gaatcatttt tcttaagagc tggtggatgt
      301 aatactgagt ggatgaacgt ctttttagaa gagctttcac aagcttatcc atatgattat
      361 tttttactcg ttatggacaa tgctatatgg cataaatcaa gtaccttaaa gattccgact
      421 aatattggct ttgcatttat tcctccatac acaccagaga tgaaccccat tgaacaagtg
      481 tggaaagaga ttcgtaaacg tggatttaag aataaagcct ttcgaacttt ggaagatgtc
      541 atgaatcaac tccaagatgt catacaagga ttggagaagg aggtgataaa gtccatcgtt
      601 aatcggagat ggactagaat gctttttgaa agcagatgag tattatatgc aatttcttta
      661 tataaaaaga ccggattgct ccgatctttc aatagttcat attctcaatt tctattttaa
      721 aaatagctaa ggttaacgtc aaatgactac gcgacctatt tcatacgata aaaatcaagc
      781 actagaccag caggtccttg aactaataag gactctgttc cccaatcggt tacagttggt
      841 ccgtgtaaaa actttatacc aagctcgttc aaccgtttgt agttctggtc tacatcctca
      901 atctcgatat gaataatgat tcctgactga aagttttcca aaggaaccaa atgattttgt
      961 gacaacataa ggcagtgact accaatcgta aactgagcaa aaccatcatc agcataatct
     1021 gcctttttat ccaagatatg ctccaagtca gcacagactt ggggaacatt tgaaacgata
     1081 atatctaatt gatttaaatt catttactct cctccataaa aagaccggat tgctccgatc
     1141 ttttaaagtt ctgctctatg aaaatcaaag aataaagtct acaagtttca tatttgattt
     1201 tcggcgagag gaattattta attgcgcgtg attgcaatcc ttcttcttcc aagaagagac
     1261 ggaatggtac gagttcttct gcttcgtatt tttccttgaa ggctttgata gcttcttctg
     1321 agtgaagttt tggatccaat tcaagtactt ctactggaag tggacggtgt tgagtgatgc
     1381 gagcatcgat gacaacagtt ttaccttctt tgttcaattt aacagcttct gcaacaactg
     1441 catcgatgtc ttcgatacgg tcaactgtga atccaacagc tccttgagct tccgcaattt
     1501 tagcgtagtc agcgtttgtg aagtctacac caaacaagtg tttgtttgta tcttcgtatt
     1561 tgttcttgat gaagccgtac tcagcatttg agaagacaag gttgataact ggaaggtcgt
     1621 attgaacgtt tgtgataacg tctgggtagc acatgttgaa tgctccgtca cccatgatgt
     1681 tccatacttg gcgatctgga ttgtctttct tagcagcgat accaccagga agggcaatac
     1741 ccattgtcgc aaagagtgga gatgtacgcc acatgttctt aggtgtcatg tgaaggtgac
     1801 gagtagatgt ttgagtagtg ttacctacgt cgattgagta gatagcgtct tgatcagcat
     1861 gtttgttgat tgcattgtaa acttgataca attgcaattc accctcagtt ttaccttcga
     1921 gtttgttcat gtaatcacgc cagttttggt tgttcttaac gtttgcacgc caccatggag
     1981 ttgattcaac tgggtttact ttgtcaagga tagctttagc tgcttgacca gcatcaccaa
     2041 ggattgaagc gtcaagggca tgacgtttac caagtttgta agggtcgata tcgacttgga
     2101 tgaatttttc agtgttcttg aatgcttcgt aaacttcagc aaatgggaag tttgaaccaa
     2161 ggaaaagaac tgtgtctgct tcaaagacca cttcgttggc tggtttccaa ccaacacggt
     2221 aagcagaacc tgtcaaacct tcatagttcc attcgaaagc ttcaaagttt ttaccagttg
     2281 tgatgattgg tgctttgatt ttacgtgaca attcagtaat cacttcacca gctttaacac
     2341 caccaaatcc agcatagata actgggcgtt cagcattgtt caagatttca acagctttgt
     2401 cgatttcaac ttcgttcaaa gcaggagcga tgaatgagcg ttcgtatgaa cctgaaccgt
     2461 agtatgagtt ttcgtcgatt tcttggaaac cgaagtttac tggaatttca acaacagctg
     2521 gacctttttt agaaattgca gcacggcagg cttcgtcaat tacttttggc aattgctcag
     2581 cgtaagctac acgtttgttg taaacagcga taccgttgta cattgggttt tggttaagct
     2641 cttggaaagc atccatgttc aattcgttaa ctggacgcga tccaaggatc gctaggaatg
     2701 gagtgttatc catagctgca tcgtaaacac cgttaatcaa gtgagtcgca cctggaccac
     2761 ctgaaccaac tgcaaccccg attgagccgc cgaatttagc ttgcataacc gctgcaagag
     2821 cacctgtctc ttcgtggcga acttgtaaga agcggatatc tttgtcttca gccaaagcgt
     2881 ccatcaatga gctgagtgtt cctgatggga taccgtagat tgtatctacg ccccatgttt
     2941 tcaatacgtt aagcattgct gcagatgcag taattttccc ttgagtcata atgataactc
     3001 tccttcaatt tttttagatt tggagaatac gattacatag aattggaaac gttctccaaa
     3061 tttttactat tccactgtat catatttatg ctgacttttc taaaaatctg ctcaaaactc
     3121 tctattctct attctaatac agttttgaaa gttctgtcat ttctgtttta taacaaagaa
     3181 atctagtcat tacttttagt ctattttact aaaatttaac agaagggaac tggtcagaac
     3241 agatacagaa ctaaaggcca tggctagacc tgccaattct gggttgagag ccagtccaac
     3301 acctgaaaag actcctgctg caatcggaat tccgacaaca ttgtagataa aggcccagaa
     3361 aagattgagt agaattcgat gaaaggtttt cttactcatg tcgaaggcac gaaccactcc
     3421 taaaagatta ttggttgtca acaccaaatc tgctgactcg atggcgatat ctgttccagc
     3481 tcccatagca atccccacat ctgctacact aagggcagga gcgtcattga taccgtcccc
     3541 aacaaaggct actttccctg actgttgcag tttatggatt tcatgggctt tttcttctgg
     3601 caagacgcct gcaatgacct cttcaattcc gatttgatct gcaatagcac gcgccacacc
     3661 agcattgtct cctgtcagca tgactgttcg gagaccacgt ttttttagct gactgatggc
     3721 tagcttagca ttttccttag gaatatcttg caaagcaagc aagcctttga tttcattgtc
     3781 aacagctaag aacacaactg tcttagcttc tttttctagt tcttctagtt tatcttgata
     3841 agtattagaa atatccatac catccagcat tttagcattt ccaagtaaaa cttgttttcc
     3901 attgattcgc cctgaaacac ctttcccgtg caaggactga aaattttcaa cagtttgaaa
     3961 ctcaagtcca gcttcactcg ctcgcttaac gatagcctca gccagtgggt gttgagaagc
     4021 atcttccaag gaggctgcca atccaaacac ttctacttcg tcgccgatga tatctgttac
     4081 cacaggtttc ccttccgtca aagtcccggt cttatcaaag acaagagttt gaactttctg
     4141 gatttcctgt aagacagttc catttttgag gagaaccccc atcttggcac tacgtcctgt
     4201 ccccaccata agggctgtcg gtgttgcaag tcccaaggca caaggacagg cgataatcaa
     4261 aaccgccact ccgtagagaa gagaggacac aaagctagct ccaagcacga ccacactatc
     4321 cctgagcaag acgaaccaaa cccaaaaggt catgattcct aaaatgacaa ctactgggac
     4381 aaaaatccct gaaatcttat ccgtcaagtc ctgaatcggc gcacgacttg tctgagcttt
     4441 cttcacaaaa tccacaatct gagccaaaac agtctctgag ccaacttttt ctgctctaaa
     4501 gacaagcgtt ccactatgat tgatggttga gccaatgaca gtatctccaa ctgtcttgtc
     4561 cacaggcaga ctctcacctg tcaccatgga ttcgtcaata ctagagacac cttctactac
     4621 gacaccatca acagcaatct tttcaccggg acgcactcga atcaggtcgc ctaccttgac
     4681 ttgttccaaa ggaacttgga cataactatc atcactcaag acttctgcgg ttttagcttg
     4741 caagtccagt aatttctcca cagcttggga cgtatttttt ctcatttttt cctcaaaaac
     4801 tgctcccaaa agaacgaaaa agaggataaa tccagcactt tcgaagtaaa cagggagacc
     4861 agcaaagaga gcaactaggc tatagaaata agccactaga gttcccagcg caaccaaggt
     4921 atccatgttg gcattgtgct ttttaaaact ggcccaagca ctctggatat atggcttacc
     4981 tgcaactaac ataataggcg ttgttgctag aaaggttccc caatgcatga cttgatgact
     5041 aatgctacct gtcaacatcc caatcatgag aatcacaaga ggcacagtaa agatactagt
     5101 aatccaaaaa cgttgcagga gagatagaga ttttcgagtc ttctcaacga ctatatagct
     5161 tcccttttgc atcttcatgc cacaagaaaa ttcatgtcgc cctaattctt gaggtgtaaa
     5221 acgaatgact ttctcctcat ctacgccgat tggttccaag ataccttctt cttcaaacag
     5281 aatttcctta taacagtttg aaggagtagc acgatgaaag gtaatctcag ctggaattcc
     5341 cttttgaagc tggatatggg ctggatgata gcctttttca gctcggatac ggattttttg
     5401 aatgccattt tctaagcttg ctttcacaat ttctgtcata gtctccacct actctacaat
     5461 catcttgccg tgcatcatgt tcataccaca agcaaagcca aactctccaa cctgctcagg
     5521 cgtgatttcc actacatact cttcccccat tggcaggttc gcatgtacac caaaatctgg
     5581 aaaaacaatt tgatccagac atggtgaagg atccttgcgg tcaaagacaa tgcgtgctgg
     5641 cactgatttc ttgaggacaa tcaactcagg agtatagcct cccatgactt ccactcgaat
     5701 ctcttggtat ccgttttttt gctgggcttt ttgtccagat ttttcaggct ttttgaaaaa
     5761 ccaaaacaag ataaacgcga taagggcaat acaaataatg gttacaatac tatttaacat
     5821 gacgtctcct ttacatacaa ttacatctta cttctgttac agcacttgat ttcttctctg
     5881 aaatcacagc ttccaagtct tccaagtcag tctgagtaaa ttcacattct acaatcaagt
     5941 cagccaacaa attcctaatc ctacgggaac aaaccttgtc tttgatatct tggacaagta
     6001 aatcccgact ttggtctaga gttaaaaggg ctgaataaac aaaggacttg ccttcttttt
     6061 tccgagtcag acactctttc tcaaccaaac gagccaaaag tgtctgaacc gtggacttgg
     6121 accagtcaaa ccgctctgcc aaaaccctaa tcaaatctgt actggtctgc tccccctgca
     6181 tccaaataat cttcatgacc tgccattctg catctgaaat ctgcattacc atacctccaa
     6241 aatctacatt tgtcaattac actcaacagt atactcccaa aatctacatt tgtcaattat
     6301 agaaataata ttttcttcga aaaatagaat tttaatcatt tgaaaaacga tttgcagtca
     6361 aatattacta tataaacaat aaaaatatgc tatactaaag aaaaaagaaa acaaccacta
     6421 ggggtgcgta aagctgagat taacgactgt tagatccctc tgactcaatc taggtaatgc
     6481 tagctgatgg aagtggaaat gataatgggg actagcagtc ttctattgcc tttctaaaac
     6541 agactagctt gttcttaaga atacaaactt cagttggttg ggaggtttta gatgacttat
     6601 ttacccgttg ctttgaccat tgcagggact gaccctagtg gtggtgctgg cattatggca
     6661 gatttaaagt cattccaagc gagagatgtc tatggaatgg ctgttgtaac cagtcttgtc
     6721 gctcaaaata ccagaggtgt tcagctaatc gagcacgttt ctcctcaaat gttgaaagcc
     6781 caattggaga gtgtcttttc tgatattcca cctcaggctg taaaaactgg aatgttggct
     6841 actactgaaa tcatggaaat catccaaccc tatcttaaaa aactggattg tccctatgtc
     6901 cttgatcctg ttatggttgc tacaagtgga gatgccttga ttgactcaag tgctagagac
     6961 tatctcaaaa caaacttact acctctagca actattatta cgccaaatct tcctgaagca
     7021 gaagagattg ttggtttttc aatccatgac cccgaagaca tgcagcgtgc tggtcgcctg
     7081 attttaaaag aatttggtcc tcagtctgtg gttatcaaag gcggacatct caaaggtggt
     7141 gctaaagatt tcctctttac caagaatgaa caatttgtct gggaaagccc acgaattcaa
     7201 acctgtcaca cccatggtac tggatgtacc tttgctgcag tgattactgc tgaactagcc
     7261 aagggcaaga gtctttacca ggcagttgat aaggccaagg cctttatcac aaaagctatt
     7321 caagatgccc ctcaactcgg tcatggttct ggtccagtca accatacaac ttttaaagat
     7381 taagaaaaaa aactctctag ttcccacttt aagggaatta gagagttttt atactcttcg
     7441 aaaatctctt caaactacgt cagcttccat ctgcaacctc aaaacactgt tttgagctga
     7501 cttcgtcagt cttatctaaa acctcaaggc agtactttga gcaacctgcg actagctttc
     7561 tagtttactc tttgattttc attgagtatt aattaggaaa gaatgtcatg caactttgtt
     7621 aaaaaggctt gcgtttttgc ctcaatatct tctgcttgca tcaaatcacg tacaacagct
     7681 acaccagcta tgccagtgcc cataagctga tcaatattct ctgatgtcaa gccgccaata
     7741 gcaactactg gaatggcaac cgtttgacaa attgttttca aggttgaaat cagggtgatg
     7801 ggtgcatttt ccttggtggt tgtcggaaaa atggctcctg tccccaagta atctgcacct
     7861 gatttctccg cttccagagc tcttttaacc gttttagcgg tgacaccgag gattttttca
     7921 ggacccaaga ctttgcgagc taccgaaact gggagttcgt catctccaat atgcagacca
     7981 gcagcatcaa ccgcaagaca aacatccaac cgatcatcga ttatcaaggg gacctgatag
     8041 gcatctgtta tttccttgac ttgttttgcc agttgataat attgattggt tgtgagattt
     8101 ttttctcgca attggactat ggtaacccct gaacggcagg ccgtctcaac ttttgcaaga
     8161 aagctttcca cggaatcttg atagcgattg gttaccagat atagtctaag cgcttctcta
     8221 ttcataaacc tctcctttga tggtatctag ccaattttca tctcttctta ggagcgaaag
     8281 ctgattgagt acttggtaac gaaattcttc caatcccatt ccttgaacaa ctattttctc
     8341 agcagcgata ttgagataag agactgctaa gcaagaagct tcaaaaccag tctttccttg
     8401 gctgagaaaa acagctgtta aggctccaac caagtctcct gtccctgtta tccagtctaa
     8461 ttcagtacag ccattctcaa gtacagcaac ttgattctcc gaaacaataa ggtccttggg
     8521 acctgtgact aagaatgaca taccaggata ggtctgacac cagtctttca agacttgaag
     8581 caaatcctcc gtttcttaat ctttagcact cgcatcgacc ccaacgccgt ggtgctttaa
     8641 accaacaaga cttcgaattt ctgacatgtt tcctttaagg atcgtagggc tatagtctaa
     8701 aaggtctctg actagtccct tacgaatggg cgacgctgat acaccaaccg catctactac
     8761 catcgggaga gaagattggt ttgcatacga agctgccatg cggattgctt tttccttctc
     8821 agctgacaaa tgccccaaat tgatgaagag agcctgactt tgcttagtaa aatcaagaac
     8881 ctcacgggga tcatctgcca tgacaggttt gcatcccaga gccaaaatcc catttgccag
     8941 catctcacaa gaaatctcat tggtcataca gtgaatgagg gaactagagc ctataggaaa
     9001 aggatttgtc aatgcctgca tcattctatc ctttcagcaa agaaatatcc ttgcactttt
     9061 ttaaagaatt cctgcttgat taaaaatcta aatgcaataa aggaaatcgc tgtaccaatc
     9121 aaggttgctc cgaaaaatcg aggagtgtag ataaaccaac taagcttagc agccgatcct
     9181 gtaaagagca ccataacagg ataggaaaca atagaaccaa taatacctgt tcccacaatt
     9241 tctcccaagg cagaaaagta aaattttcga ccgtacttat aaaagagacc tgctagaagg
     9301 gctccaaaag tcgctcctgt gagagctaaa ggcggaatcc cttgagtcgt catacggata
     9361 aaggctgtca ctgtagccat agccaaggca taaacaggtc ccatcatgat tcccgctaga
     9421 atattgacta cactggacat cggtgccatt ccctcaatcc gaaagatagg tgtaaggact
     9481 acatcaaggg caatcatcat agataaaatg gtcaatttgt gaacttgtag ttggtgcttt
     9541 ctcatgtttc tattcttctc ctttttctaa agactgtaaa tcgctcttcc atgtctggtg
     9601 ttggtaggcc atttcccaaa acttggcttc catatgaaca ctgatgtgga aggcatctag
     9661 cattttttgc ttatctgtct catcactttc tcgatagagc tgattgacca gtgctccctc
     9721 ctctctgatc tgttgctcta actcatccgt aatataagtt tcaatccatt gttgatagag
     9781 aggatttggt gatggtttaa gattaagtga tttgcctata tcatggtata accaaggaca
     9841 aggaagcaag cttgcaaaag cgatggctaa gttcggctct gcaaattgcc tataaatatg
     9901 agaaatgtaa tgataacagg ttggagcgat tggatgttgc tccatttcct ggtcgctgat
     9961 ttccaattcc ttgaaaaatt gttggcgaat aaataactca ccctccacta aaccctgagc
    10021 attttgtttc aagagtcttt tcatctcttg gtttgaagtc ttatcagcca aaagatgata
    10081 gatttctgag aaggccttca gatagtaggc atcctgaatc aggtaatagc ggaaaatggc
    10141 aggttctaaa ttcccctctt gtaattgtaa aataaaggga tgatgaaagg aagcctgcca
    10201 agctttcttg gataattcca tcgcaatatc tgtaaattcc ataataactc ctttataaaa
    10261 atagactggt ttgaagcaat aaaaagaaaa gcaggtagat taattttgtt tttttaggaa
    10321 tataaaaagt ccgatagcta ttcttcaact gtgcatgttc gtcatatccg tgagcagata
    10381 gagctctcag gtaaagatgg cgccacctaa agactgtcat cagaacctta ctgtaaatca
    10441 agggcgacca aaaatgtagt tcttgaccac gtaataggca agcttctttg agggacttga
    10501 tttcttgctg aatgagagga aaagaattga ataccacaat caaggcatag gaccaagagc
    10561 gtgatagccc cttttgagcc aagtacaaga gaagctcttt tagtgaaata gaggaaacaa
    10621 agacaaggcc gatacaaact gtcacaaagg ccctcgttcc aagcatgact gcctgtgaag
    10681 catctccgtg taactgaact gcccagtagt tggcaaaaga tggtaaaatg gcaagtatga
    10741 tcatccaagc taacatttta aatcgacggt aatagagcat aaagagaata caaaatgcga
    10801 ctaccgaaag attcagagca atcgaaggaa tgaaagatgt ttccaaggat aaaatcagca
    10861 agaagagact gataatcggt gtctgggttg ctactttgac catactatct cacctcccct
    10921 tgggtattgc tactctgaga tgtaagtggt ttggtaatgg tcacttcttt cacatgccga
    10981 agaccctgac tagtcatctc aatccaataa tcaaccacag aaatcaaagg gtctaaacga
    11041 tgactaatga gcagaaaact tcttccttga ttcctctcct ccacaatcca cttgcaaaaa
    11101 taatggcagg ctctatcatc caaacctgca aaaggttcat ctagcaagat cacggaagcc
    11161 ttactggtca agatggtcaa gagctgaaga attttttgct gaccaccact taattgatag
    11221 ggactcttat cgactgcctg ctccaaatca aaatatcgta aagcttgaaa aatccgctga
    11281 tttctttcag aatcaggtcc atctaattga agctcctctc gcagactgac tcggataaac
    11341 tgcttctcag cttcctgaac aacacccgtc agatcacggt acaaactctt tttctttttc
    11401 aggactgtcc ccttccatgc aatgcgcccc ttatactttt gaaattgaag aatagagcga
    11461 aagagggttg atttcccgac accattgtca cccaggatac aggaaatccc ttgatagaat
    11521 gtgaaatcag caattgaaaa gagggggcga ttaccaagct caccagtcac acggttcata
    11581 tggaatagtt ccgggctaga agcaacttcc tttgaagcaa cctgtgtcat ctcataggaa
    11641 gggatttgaa acacttccct tagttttccg tctcttagct caaccatata gtcgatatag
    11701 gctttatagt cagataaatc atggtcgcac aaaatgactg tcttcccatc aagagccaac
    11761 tcttttagaa tctccaatat ctcgattcta ctcttgcggt caatggaagc gaagggctca
    11821 tccaagagat agaccctagg attcatggca aagaggacag ccagcgctgc tttttgcttt
    11881 tccccacctg ataggtgatg aatgggacgg tgtaagattg cctcgcaacg acattgctgg
    11941 acaacctctg ctattttaga atcaatttcc tgaaggtgat agccgatatt ctccaaggtg
    12001 aaaatcaact cctcaaacaa gttctccatg gtaaattgat gattgagatt ttgcaagaga
    12061 atgccaacct tctggacacg tgcgatgata gaaagctgac tgacctcgct cccatctatc
    12121 aggacttgac cactataggg aagagaactg acttgggcaa tcatttgaaa gaggctggat
    12181 tttcctgaac cactgctccc aactaacaag gtaaaggctt gcgcatgaaa agtaaaatca
    12241 aacggctcag agaaaattgg ggactgaatc gctcgtagtt ccagacccat ctatgctttt
    12301 cctccagttg caaactgatg atagagtttg acaatggcac gaaccaagat ggtacagaag
    12361 aaataaacag aaataaaacg taccacaagc aaggaaagga caaacggaag ggaaaaggcg
    12421 tagtaaccta acttaatgta ttcatagaca aagctaacaa gcgtaatccc aatactatta
    12481 gcagttagag agagccaact ttcatagcga ttcttagtta cgataaaacc aaattcactt
    12541 cccaaacctt gaaccaagcc agacaaaaga gctcctagac caaattggct accataaagg
    12601 acttcagcaa gcgcagctag cacttctcca atcgttgcac ttccgactct cggaacaaag
    12661 atggcagcaa tgggcgcagc catacaccag agaccgaaga ggatttcatt ggcaaaggcc
    12721 tgcaaaccaa gaggtgttaa gagtagactg agaatattat acacatatcc tgaaccaacg
    12781 aaaaccccac caaaaaagat agacaagaaa gcaagcaaga taacatcttt taactgccat
    12841 tttttcaaca taaaaaaact ccttttttta aagaaaagtg gggcactcaa gaagaccgac
    12901 ctaaatactt tgtatagcag actgaattta gaacagtaca caagaacact aaaatatttc
    12961 tagaaattaa tttgaatttt ctaattgatt tgttcgcatc ttatttcaat ctactatatc
    13021 atcttcatcc agtttcgtaa aagaaaaaac tctaattaca gatacgaatt agagttcagc
    13081 ttacaagatt agacagttct tttcgacata cgaaaaaaac atttcacatt tcccttcgcc
    13141 agtcttaact gtatcaggtt caatgggtat catctcagcc taaagcaccc caaatgtctt
    13201 tattatttaa ttatgtgatt attataacac acattttata ctagttcaag aaattgaact
    13261 ggaaatacag ccttgcactc acaaagacag cagatctttc ttttgcaaaa aacaaatgac
    13321 ctgtttgatg aattagccat tcaagctgaa tctggacata gctttttaaa aaaggaaaat
    13381 cctacttact tagaatccaa ggatagatat ctattgttca ctcatttccc gaacagtttt
    13441 ttctatattt tttgcatacg atattgccga aatgattgaa acgccatcca tattggtctt
    13501 tataatgtct ttaatatgtt tcgtctgtat cccaccaatt gcaactaaag gcatttgtgg
    13561 caatagtttt ctcatcaatt taacaccttc ataacctata gcaccaccag catcatcctt
    13621 tgactgggta tcaaatacag gaccaacacc aacataatct acatattcaa cttttgattg
    13681 ttgaaattct tcctcgtttt ttatagaaag accaattatt ttatctggca tcaattttct
    13741 aatttcatca acaccaatat catcttgacc tacatgtacg ccatcagcgt caatttccat
    13801 tgctaaatct atatcgtcat taacgataaa tggaacattg tattttttac aaagttcttt
    13861 aatttggata gctagctcaa gtttttctaa gccttctaaa gcaccctcac ctttttctcg
    13921 aaattgaaat aaggttatac caccttttaa ggcttcctca acgactgtat atagattttt
    13981 tccttggcaa gtagtcgttc cacaaataaa atatagtttt agtaattctt tatgaaacat
    14041 cttacttcac tcttttgaat tcctttacat cttcatctgt aatctcgtat aaggcattta
    14101 taaattcaac tttaaatgtc ccaggaagat gtccatttgg acgtttttct gccatttctc
    14161 cagcgatatt gtaaactaac attgctgttt ctaatgattt caattcttga cctttttcta
    14221 gtccgataaa gcttgctact acagctccta ataagcatcc tgtcccaatg actttcggca
    14281 tcatagcact accattatga atcgttacca cttctccatt aacagcaatg gcatccactt
    14341 cacctgttac tactattgga atattgaact tctcatttgc tgctagagca atttcgtcaa
    14401 tattatctac gcccgcacta tctactcctt tagatgccac atctattcct actaaagagg
    14461 caatctcgcc agcatttcct ctaatcgctg ctagtttata attgttgatt agatcatctg
    14521 ctactttttt tctatattct cctgctccac aggctacagg atctaaaact gctgggacat
    14581 tatatttctc cgcaattttc agagcagctt ggtataattt ccaattttca tctgtcaatg
    14641 ttcctatgtt tattaataaa ccaccagcat actttaacaa atcctctaaa tctgctggaa
    14701 actcactcat ggctggtgag gcgcccagtg ctactaatcc atttgctgtg aaatttttta
    14761 ctacatcatt ggttatacaa atgaccaatg gtgctttttc ttttaataat tttaaacttg
    14821 tcatattgaa atccttcctt ttcactttat acgatctact gatttcgatt tatctctatc
    14881 tttcgttaag aaattttttt catttacgtt gaatgattta tactcaatga aaatcaaaga
    14941 gcaaactagg aggctaaccg caggttgctc aaaacactgc tttgaacctg tagataagac
    15001 tgacgaagtc agctcaaaac actgttttga ggttgtggat agaactgacg aagtcagtaa
    15061 ccatacctac ggcaaggtga aactgacgtg gtttgaagag attttcgaag agtcttacct
    15121 catcaaattt gtaaatatca tgagccttct ctagacatcg taaccaatat caaaaaaagc
    15181 taattctaaa gcgactgctt gattccagcg ttgctgaagt tctgtcaaat cttctcgatt
    15241 tttaccgaca cgattgagtt cgtcaaccag aaattgaacc cactctgcaa agaaaggacc
    15301 tctgtggaga ttgatccatt ccgaatgaat atagacttca ggtagagcca aatctttaga
    15361 accccagtct aaatagagac cttctgcaat gaccagcatg accaaaagat gggcatagtc
    15421 tgatgaagcc actgccgaat acattagatc ctgaaaggct tttgttacag ggtgcaaagt
    15481 cacttctaga tagtcattct ctgctacttt taactcttta aaagcctttt ggaaataacc
    15541 atcttcatct gcttcaagaa agcctagttg cttggcaaaa cgaagcttgg attcaagttt
    15601 atctgcgtga gctacgcagg cacccagcat ggataagaag gcatcaaaga agtgataatc
    15661 ttgaatcaga tagtccttta agaccttatt ctcaattgtc cccgcaaaaa gttccttaac
    15721 aaaacgatga ttgattgcag cctgccaatc cttctgactg ctttttaata attctccaac
    15781 agtcaaacct ggctgaaatg catagtcttg tgtttccata tttacttctc ctctctttac
    15841 ttgttagtaa ttaataaaac agcaagaaat atcaagcaaa atcgtaattc cacttgatcc
    15901 ttttaaagca catcgagagc atttgcagag agctaactaa acaagcctat ccagtttata
    15961 taaacaaaaa actccaatta caatcaagaa ttagagttga cttacaagat tagatcgttc
    16021 atttcgccat acgaaaaaac gtttcacatt tcccttcgcc agtcttaact gtatcaggtt
    16081 caatgggtat catctcagct taaagcaccc caaatgtctc tattatttaa ttactgaacc
    16141 agtatagcaa aaaatgaaag ccctagcaag atatttgacc gaaaaatatc tttatatagt
    16201 agattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat cgatttaact
    16261 gtcctgattg atttgtccta ttcttatttc attttactat agttttcgat agcgatttat
    16321 tcttccaata cacgaagaaa aacctccaca ttcagtgaag gcaatctgtt ttatcaatac
    16381 aattttaagt cacgagggtc aactgggaag gttgggttgt atggattgtg acggagctta
    16441 aagtgtttga catcttcaat ggtctgagct ccagacaatt gcataactgt cttcaattcc
    16501 gcattcaagt gttcaaagac ttgacgcaca ccgacactac caccgagagc caagccataa
    16561 ataacagggc gaccaatagc taccaagtct gctcctgaag ccaaggcttt aaagacgtgt
    16621 tgaccacgac gaacaccaga gtcaaagaca atcggcacac gtctatcaac tgcttctgcc
    16681 acttcttgaa gcgagtcaaa ggcagctggt ccaccgtcga tttgacgacc accgtggttg
    16741 gttacccaga taccagaagc tcctgcagca agtgaacgtt caacgtcctc acggcattgt
    16801 ggtcccttga catacacagg aagaccagag tattcagcga taaattctac atcgcgtgga
    16861 gacaagcgtt gtttagctga tttgtaaaca aagtccattg atttaccagc accttctggc
    16921 aggtattctt caacaatcgg catgccaact gggaagacaa aaccattacg cttatccact
    16981 tcacgattcc cccctacagt agcatctgcc gtcaagacaa tcgctttata accttcagcc
    17041 ttcacacggt ccatgatgtg gcggttgata ccgtcatcct tactaaagta aaattggaac
    17101 caatggggtg tcccttgaag ggcttcagaa atctctggaa ggtcaacagt agagtaagaa
    17161 ctggttgtat aaagagaacc aaactcatgc acaccacgcg cagtcgccac ttccccctgt
    17221 tcatttgcca atttatgagc cgcaacaggt gccataatga ttggagaaga tagtttttca
    17281 cctgcaaatt caatctctgt acttggattt tctacattgc aaagtgtatg aggaacgatg
    17341 agcttgtggt taaaggcacg gatattctct cttaaagtga aagtatcttc cgccccacta
    17401 gcgatatagc caaatgctgc tttaggaata acttgttgcg ccattggctc caaatcatag
    17461 gtattgatga agtctacatg accttctgca ttgcttgttt tgtatgacat aaactgtcct
    17521 cctcgattaa gtaagcgttt gctttttact atacaactat aataactctt ttttcaatca
    17581 ttttcaagag ttttgcttaa aaaccatctt attttttcat acaatatact agccctactt
    17641 tccttaaact ctaaacctta gtctatatta agtgaatcgt tgagattttt tgctgccagg
    17701 catttgaact acttttttat ttgctgattc tatctactaa tactataaaa aacaagtgaa
    17761 taagacacca gaacatcctc taataggacc tatggactta tatcagtccc atatatactg
    17821 tttaagcaag atactatcct agttgacgct aacttcctat cccacttatt aattttttat
    17881 ttatagtgaa tctgaacaaa tcaattgggg aatccaagtc aatttctagt actttttgaa
    17941 cagtttcagc gtactatcgt aaaatgaaat aaaacatgca caaattgctt agggaattta
    18001 aaccaatttc taacaatgtc ttagaaatca aagtgtacta tttcaacttc aatatactac
    18061 acttcatttt ctccttaaat tcagtctctt tttgaatcaa aaaatcctct ggtaagagcc
    18121 agaggataag aatttatttc attgttggga agagcaatac atcacggata gttgttgtat
    18181 cagtgaggag catgcagaga cggtcgatac cgattcccaa accacctgtt ggtggcatac
    18241 cgtattcaag agcttcaatg tagtcatagt cgattcctgt cgcttcatca tcaccaagtt
    18301 ctttggcttt agcttgggct tcaaaacggc taagttggtc gattgggtcg ttgagttcag
    18361 taaaggcatt accgtactcc ttagtcatga taaagagctc gaaacggtca gtaaagcgtt
    18421 ggtcttcagg atttttctta gcgagtggag atacagctac tggatgtcca tagacaaagg
    18481 ttggttggat taaagtttct tcaacaaact cttcaaagaa ggcattgatg atgtgaccaa
    18541 cctcagtgta gtgtttctca actggaactt tcttctcagc agcgatagct ttagcttctt
    18601 ctaaagtcat gtcttgccag aaatcgacac cagtaatttc tctgatagca tccaccatat
    18661 gaacacgctt aaatggttcg ttaatcttga tttcagtacc ttggtagttg actgggccat
    18721 cgcccttaac tgatttagca gcgtgttgga taatgccttc cgtcaagtcc atgatgtctt
    18781 ggaagtctgc ataagcttgg taaacttcga tagaagtaaa ctcagggtta tgagtagcgt
    18841 ccattccttc gttacggaag atacggccaa tttcatagac acgttccata ccacccacga
    18901 taaggcgttt taagtgaagc tcagtcgcga tacgaagcac catgtcaatg ttttgggcat
    18961 tgtggtgggt gataaatgga cgggcagcag caccaccggc ttcattatga agaacaggtg
    19021 tttccacttc aaggaatcct ttttggtcaa ggtaacgacg gatttcagag atgatttttg
    19081 aacgagtgac aaagcgttca aagctttcac ggttagaaat caagtcaagg taacgtttac
    19141 ggtaaattgt ttcaacgtct gtcaaaccat ggaatttctc aggaagagga cgaagagcct
    19201 tagacaagtg tgtgatgtgg gttgccttga tagagagttc tcccatatcc gtacgcatca
    19261 cttcaccttc gacaccaagg aagtcaccaa ggtctgcttt tttgaagatt tcgtagtttt
    19321 cttcaccgac agcatcctta cgaacgtaga tctgaatctg gccttcgcgg tcttgaaggt
    19381 gggcaaaacc aacttttcct ttaccacgtt tggttaccaa gcgtcctgcg atagtagctg
    19441 tttcgttttt atcgtgtaat tgttctttat cgaggttggc atatttatct tttaattctt
    19501 gtgaatttgc agtacgttca aaacgttttc cgaaaggatc gattccttgt tcgcggagcg
    19561 cagccatttt ttcacggcga acgatctgct ggtcatttag ttcttccata tgttctgtag
    19621 acatgggatc ctcctaattt tactcaaaat tgaatacgat gagtcatttt ttgcgatacc
    19681 cccattttat cataaataag caagaaattc acggataatc tttaaaaact aaaaagaacc
    19741 tgacgctaaa atcactggaa agaagtgaaa gtatctcccg ccccactagc gatatagcca
    19801 aatgctgctt taggaataac ttgttgcgcc attggctcca aatcataggt attgatgaaa
    19861 tctacatgac cttctgcatt gcttgttttg tatgacataa aatgtcctcc ttaataagta
    19921 agcgtttact ttgtatatta taaaaatatc ttaactcttt tttcaaaact tttcaaatat
    19981 tttgtttgga aatttcagaa attttatgtc tatggtaaaa aatccttata acggcaataa
    20041 aaaatagata ttatccaaag aagattttaa gtgctacaat aactgtatta tttctagatg
    20101 ggaggttcta tttttggatt ggtccattgt tgaacaatat ctaccactat atcaaaaggc
    20161 attctttctg accttgcata ttgcagtttg gggaattttg ggatcctttc tgctcggttt
    20221 aatcgttagt atcatccgac attatcgaat ccctgttttg gcgcaagtag cgacagccta
    20281 cattgaattg tcacgtaata cgcccctttt gattcaactc ttctttctct acttcggtct
    20341 tccccgaatc gggattgtcc tatcttcaga agtctgtgca acgcttgggc ttgtcttttt
    20401 aggaggctcc tatatggcag aatctttccg aagtgggctg gaagccatca gtcaaaccca
    20461 gcaggagatt ggcctcgcta ttggtctgac acctctacag gtctttcgct atgtggttct
    20521 tccgcaagca acagcggtgg cactcccctc ctttagtgcc aatgtcattt tccttatcaa
    20581 ggaaacctct gttttctcag cagtggcttt ggccgacctc atgtacgtcg ccaaggattt
    20641 tattggtctc tactatgaga cagacattgc gctagctatg ttggtagttg cttatctgat
    20701 catactgcta cccatctcac tggtctttag ctggatagaa aggaggctcc gccatgcagg
    20761 attcgggaat ccaagtactc tttcagggaa ataatctcct gagaatctta cagggattgg
    20821 gcgttacgat tgagatatcc atcctgtctg tcctcttatc catgatgttc ggaacagtca
    20881 tgggaatcat catgacctcc cattctagaa tcatacgatt tttaacacga ttgtatctgg
    20941 actttacccg tatcatgccc cagctggtgc tactcttcat cgtttacttt ggcttagctc
    21001 gaaactttaa tatcaatatc tcaggtgaga cttcagctat tatcgttttt accctctggg
    21061 gagcagctga aatgggagac ttggtacgtg gagctatcac ttctctccct aaacatcagt
    21121 ttgaaagtgg acaggcactc ggcttgacta atgttcaact ttactaccac atcatcatcc
    21181 cacaagtctt aagaagactg ctaccgcagg ctatcaatct tgtcactcgg atgattaaaa
    21241 ccacttcatt agttattttg attggggttg tggaagtgac caaagttgga caacaaatca
    21301 tcgatagcaa tcgcctgacc atcccaactg cttcattttg gatttatgga accattctag
    21361 tcttatattt cgcagtttgc taccctattt ccaaactatc cactcactta gaaaaacatt
    21421 ggagaaacta aatgtctgaa actatcttag aaatcaagga actaaaaaaa tccttcggag
    21481 acaatcccat cctccaagga ctttctctag aaatcaaaaa agggaagttg ttgtcatcct
    21541 agggccctct ggttgtggga aaagtaccct ccttcgttgc ctcaacggct tagaaagtat
    21601 tcaaggtgga gatatttttc tggatggtca gtctatcgtt gaaaataaaa aagattttca
    21661 cctagttcgc caaaagattg gcatggtctt tcaaagttat gaactctttc cccatctgga
    21721 tgtcttacaa aacctcatcc taggccctat caaaactcaa ggaagggaca agaaagaagt
    21781 aacggaagaa gctttgcaat tactagatcg tgtcggtttg ctggataaac aacatagctt
    21841 tgcccgtcaa ttatctggtg gacagaagca acgtgttgca attgtccgtg ccctcctaat
    21901 gcatccagaa atcatccttt ttgacgaggt gactgcttcg ctggatccag aaatggtgcg
    21961 tgaggtgctg gaacttatca atgatttggt ccaagaaggc cgtaccatga ttttagtaac
    22021 ccacgaaatg cagtttgccc aagccattgc tgaccggatt atcttcctcg accaagggaa
    22081 aatcgctgaa gaaggaacag ctcaagcctt ctttaccaat ccgcaaacca aacgagccca
    22141 ggaattttta aacgtctttg actttagcca attcggctca tatctataaa ggagattctt
    22201 atgaaactat tcaaaccact cttaactgtt ttagcacttg cctttgccct tatctttatc
    22261 actgcttgta gctcaggtgg aaacgctggt ccatcctctg gaaaaacaac tgccaaagct
    22321 cgcactatcg atgaaaacaa aaaaagcggt gaactgcgaa tcgccgtgtt tggagataaa
    22381 aaaccgtttg actacgttga caatgatggt tcttaccaag gctacgatat tgaactagga
    22441 aaccaactag ctcaagacct tggtgtcaag gttaaataca tttcagtcga tgctgccaac
    22501 cgtgcggaat acttgatttc aaacaaggta gatattactc ttgctaactt tacagtaact
    22561 gacgaacgta agaaacaagt tgattttgcc cttccatata tgaaagtttc tctgggtgtc
    22621 gtatcaccta agactggtct cattacagac gtcaaacaac ttgaaggtaa aaccttaatt
    22681 gtcacaaaag gaacgactgc tgagacttat tttgaaaaga atcatccaga aatcaaactc
    22741 caaaaatacg accaatacag tgactcttac caagctcttc ttgacggacg tggagatgcc
    22801 ttttcaactg acaatacgga agttctagct tgggcacttg aaaataaagg atttgaagta
    22861 ggaattactt ccctcggtga tcccgatacc attgcggcag cagttcaaaa aggcaaccaa
    22921 gaattgctag acttcatcaa taaagatatt gaaaaattag gcaaggaaaa cttcttccac
    22981 aaggcctatg aaaaaacact tcacccaacc tacggtgacg ctgctaaagc agatgacctg
    23041 gttgttgaag gtggccatta actcttaaaa gggactggat tttaagctcc aatccctttt
    23101 taagatttta cctataacat cctgagtcta tctaagatgt tcaatctgaa cacagtgtac
    23161 atactttatc ttctattgca tatactttat cacataagat acgaatatcc tcttcactat
    23221 gactagcaat caaaattgtt gtcccttttt cactagagag ctttctaaac aatgttctca
    23281 tattttctac acttgattta tccaaggcat tcataggttc atctagtaaa agaatagagg
    23341 gattctccat aattgcttga gcaatcccta gctttttcct catacctagc gaataagttt
    23401 taactttctg gtctttttgc tcatatagac caactatttt cagtgtatca ttgatttcct
    23461 gattaccaac tactcctcgt atgcttgcca aatattgtaa attcttaaag ccactataat
    23521 aatttataaa accaggttct tcaatcaaag ctcccaaatt agttggaatt tttctctcag
    23581 gaacaatatt ttccccattg attaacactt ctccataaga cggactatat aaaccagcta
    23641 ttaatttaaa caatacactt ttccctgagc cattcgcacc agtaattcct ataatttccc
    23701 cctgtttaca actaaagtta aggttttgaa aaacacatgt cttttttaat ttcaactcaa
    23761 tattttttaa tgtaattatt tcattcattc tataaacctc ctcttttgac gagtgaaata
    23821 gaaaatgctt tgaaaaagaa agactaaaaa tagcaactga agaaataaat ctcgtcctat
    23881 atctccattc cctcgattca aaatataaaa tagataatta gttcgatttc ctacaaatag
    23941 accaccaaac acaatcatga gtaaaaagaa actaacgcaa gcaaagttca tttgtacatt
    24001 cgctcctagt gcgtataaca taaagcaaaa caagactaac acacaagcat tcaaagaatc
    24061 aactataaac aaaactccta tatcccagtt tggtaactgt aacataaatt gaatcactag
    24121 aacttttacc atgattaaaa tgagtccata aagaaaacag gtccaaatct gatacctaat
    24181 ccagagctta atagaagaaa atcgaatcac ttccataaag aaatcggatg ctcttctacg
    24241 atatacaact gctagaaaaa atgtatgaat aataaaccaa tgaagcaacc atatagataa
    24301 gactaaaaaa gagttttgac tcagattagg cccttttaaa atttctataa caagtctatc
    24361 atttccttct aaccaatacc ataatcctaa acaaatcaat atccaaaaaa gaacataacc
    24421 ccaaaagtac ttggtataga ttatctgatt caacctccac atgtgactac ttaactttcc
    24481 catttccaac ttttacactc tcctccagtt tctatgaaca gaaaatacag tcaatggaat
    24541 tatgatagat agtaatgtaa gccaataaat caatgcatac ggattggaat ttaccatata
    24601 ctgaaaaatt ggcaataatc caattatccc attgtccaac tgataaatcc agaataagga
    24661 ttctacaaat aaaaaagtaa acagaaatac taagctcatg tttgattttt taaaccaaga
    24721 aaaactgcta atagtaagta aggataaaaa gaaatagtat gctatataag agaaaaaaaa
    24781 tcctataaag aaactagcat tgtttgcaat acttatacca taaaattctc ttaaaaaatc
    24841 aacctccttt atctccaaag agaagctaaa accattacta aatgcaatca gaaaaatcaa
    24901 taaaaataaa gtcgccgtcc aaatccccgt actaagagct gctaatttga aactaaaact
    24961 ggtaaagtgc ttaattgatt tcagacgaat acgacactcc aacctattaa aatagttatt
    25021 catcaaataa aaaaagaata atatatatgt gaacggaaag caatatactc cagtcgtcat
    25081 atcttgaagt aaaactaaga tccattctaa tacatttgga tggattgaat attggcgaca
    25141 gcgcaataaa tatactgtac tagataaaac acaggatagc agtaatataa aataaaccaa
    25201 tactgctaag aaatcttttt tataaaattg aacaaattgt ttcattatac atagtcctct
    25261 gaatgtagaa aaaatgtacc ataaacaacc aaacaactaa caaataaaat aaaagcaaga
    25321 tgcccactaa ctaaggaaag actgatatct ttctgatatc ccaaagctag cgttgtcaca
    25381 ggttctaagt aagatagccc taaaatagcc caaaaaatac caccaaccat catataggca
    25441 actgggatga aaatagctcc tatttttttc ttcactagca aagcactagc tagtccaaaa
    25501 atagagaaca cagcgcccca aactccatac cagagagtcg ttacaagacc atagagaaac
    25561 tgattggaat caaataattc ttttaaggca ccactataat ctccaatata aatttcctga
    25621 taaggagtca ctaaaagatt aattcctaat aataataaat aggggagaaa aaagactaga
    25681 aaagaagaaa taattgcagt actacctaca atagctagat acctcttttt agaaattcgg
    25741 cacaattgtg ctgttagaaa atgactctca gcatcctcta ttatctgact agaatagggc
    25801 agtgtacaga taagtgcagc tactaggcta atcggtgaaa atcctcgaat agaagaagcg
    25861 gcaaaaaaaa tcgataaacc ttcaatttta taaataccat tgaaagcaag gaaatttcct
    25921 aaactcatgc aaagaagggt caaaaataaa gacatataaa atcgaggtga ttgaacgact
    25981 cgtacaagat tacaaatgaa aaattccatc cttactcctc cttataataa aaatagggtg
    26041 tagcattctt ttttcatgct acacccacaa tcaaccatct ttaaggctta ctctgacaag
    26101 taagttaata agaatctgga ctccaagaac ctgaagtatg aattcttaca tgatttccaa
    26161 attgtggcgc catagctaat ctagtaccag aaccaatata attgtcacca cctccattat
    26221 agtacatgac aatcctagag ccagacccca atgaatatac cggggtaata tctgacccac
    26281 tataggcgct acgaatagag gtatttaacc ttttaccgcc accagtgctg tcactattat
    26341 taattccagc agaggcgttt tctttctcaa gctcactagt tgtatccgaa ccccaacgcg
    26401 gcaacgttaa atcataattt ccaatctgtc tagctaaaac tgtagggaga aacaaactag
    26461 atgcaattgt aactacgcaa aaaaggaata tatttttctt cttttcatga catcgtcctc
    26521 ttaagaagtg ataaacaaga tagttgattg atcaatttga tacatattac attttcatta
    26581 tatcaataaa agaaagcgtt gtcaattatt ttatttaaaa tattgtcata ttttaaataa
    26641 aatggtaaaa gagactcggt agcctcgtct ctctttatct tactgaccta accttcttgc
    26701 caattttctt ggtcttcttt aaagcgtttt agaagatcaa ggccctctgg cgtgatgtaa
    26761 ccttcttctt gggctagatg gataagctcg ctatagtttg aaagcgtcac aagtttaaca
    26821 ccagcatctg caaagttctt atctgctttt ggcaattggt agctgaaaat cgctacaact
    26881 ccaagcacat ctgctccttc tcgcttggct gctgctacag cttcaagaac tgaaccaccc
    26941 gttgaaataa ggtcttcaac cactaccatt ttttgacctt gagctacgcg accttcgatt
    27001 tgattaccag ctccatggtc ttttggtttg ctacggatgt aggcaaaagg caagtccatc
    27061 ttatcagcaa taatggctcc gtgtggaatc cctgctgttg cagttcctgc aatcacttct
    27121 acttcaggaa aggcttcttt gatagcttcc acaaaaccat tttcaattag ggtacgagtt
    27181 tctggatagg ctagtgtcac acgattatca gtgtaaatcg gtgacttgat accagatgcc
    27241 caagtgaagg gttcctctgg tttgaggtaa acggattgga ttttcaagag gtggctagcg
    27301 atatctttag caagtgtcat ggtattctcc ttttattttt ctaatctagt tctttaattc
    27361 cagtcctgtg tccattcatc cttgatggca tgataagctg caacaggatc ctcagcttgg
    27421 gtaatgggac gtcccactac gatatagtca ctgccgattt gataggcatc agcaggtgtc
    27481 atgactcgtt tttgatctcc aactgcaaca ccagctggac gaatccctgg tgtcagacag
    27541 ataaaatctg gattggtagc ctgcttgatg acttgtactt cctgagccga gcaaacaaca
    27601 ccatccaagc cagcttcagc tgtcttcttg gcatagtgaa tcacagactc ttgcagactg
    27661 gtttggatat tttgaaactc ctgcatctga gcttctgacg ttgatgtgag ctgcgttaca
    27721 gcgatcaatt tggcttgact tccaagacct tcacgcgcag ccttcatcat ctctacacca
    27781 ccagccgcat gaatattggt catatccaca ccaagctgag ataggatctt cattgctgac
    27841 ttgactgtat taggaatgtc atgaagtttg agatccaaaa agacactgtg acccagggct
    27901 ttcaaataag acacaatctc aggccccgct gcgtaataaa gctccatccc taccttgaga
    27961 taaaggcttt cttctgctgg gaaaagagct aaaaattcct tgaccgcctc aaaactagga
    28021 aaatcaagag caatgactgg acgatgttct cgcataggtt tctcctttta cctttactag
    28081 tgagagagtc tggccaacag aagccacgaa aaaaggaacc tgccaacagc aaggttccac
    28141 gaaaaatggg tagtctccac cctttcaccg tctaacctta gctgcctctc tggactgctt
    28201 taaaggtttt ctattattct attatttcta ctagcacttg tcaagtaaaa acttagtcac
    28261 taaagaacta taagagaaaa ggtaaaccta gcgacgcgat gagcgctggg tcgtttgatt
    28321 tcgattgctc tcttcctctt gttttttctg ttcttcttcc tgttttttct cagcttcctt
    28381 ggcctcttgt ttggcttttt cctcagcctc cataattaat ttatccgcca cagtgtaact
    28441 gtaaattcca gcttccatgt caatcacact cggttctgac aattgtggct taatcttact
    28501 gtaatatggc agtttcttac tcatttcaga tagaggaacc aagacttcgt ccgaatcatt
    28561 catggtcaat cgaattaaat cggatgtcac cttgcttggg gctaattcca ccttttggat
    28621 agccgccttg agttctgggc taatttgagc aagttctgag acaaaaacct tgatttgttc
    28681 actatcatta aagagaactg ataaataagt ttctggtaaa ctgttcagac tcacagaact
    28741 agtctcaagc tgaccactgg aaagaatagg ataatgattt tcaccagaaa tatagtaggc
    28801 cacaatatca tattccttga ccttaatagt gaacttagtt ggaaattgat agacaagttg
    28861 agctaattca acccaatagt tagacttaat ctgcttttca tattttgcct tgtctagcag
    28921 aaggttaatc gtataatccg aatcctgaat gcctgaagcc tgtcgaatat catcagctgt
    28981 agtttgcacc gttccctcaa cacgaatatc tttcatggtc gcataaggac tgagcaagta
    29041 ggcagagaca atcaataaaa gcagacttgg aaataaaatc gtgaaggctc gcaagatatg
    29101 gataccagga atctttgctt tggctggttt ttcctttgta gcctttttag aaagcttttt
    29161 atcctgttcc tccttctctt tagactctgg ttcttctttc tcttctttct ctttgtcagc
    29221 ctctgaggat gctacttttt cttcagactc ttccttagct gattctgaat cttcctggtc
    29281 tgtttcactc tcctggtcct gtttgtcctc tgacttctca gattcttctc ccattcgagc
    29341 ttgtctttcc ttttccttct cctcagctag agccgcctct tcttcagcct tcttttttag
    29401 atattcttgg tttcgtttct gccattctga taactctttc aattcttcga ggatttcttt
    29461 gtcctcattt ttcttatctt ttgacattta ctttccttat gataaatctt ttttcaacaa
    29521 ttgataaaaa tctgctagag atttcaattc cgtagaagcc ttcatcttag cttggtaatc
    29581 ttccttgtga cttagtaagt gagaaagctt ctcttccaaa ctatccaagg tcaaatcgct
    29641 ttcttgaagg tcttctgcat agcctttttt tacaaagtaa gctgcatttt caatctggtc
    29701 accacgacta gcttcacgac caagcggcac aatgacatgc aattttgcta tcgccaagag
    29761 ctcaaaaatc gtattggcac cacctcgtgt cacaacaata tcagccaatt ccatcaaggg
    29821 ttgatagaga tcggtcacat agtcaacacg aaaaagattt tggctcaact cattcaggct
    29881 agaatctcca gttagattga taatattgta gcgctctgtt agttctttct tatggtctgt
    29941 caccaattgg ttaaagacac gagcacctgc agaaccgcca acaaacaata cagtcggcaa
    30001 tttatgatta aaatggcttt gaatatccac caattcatct ggttctggat ttttttgatc
    30061 tgaaaccttg gtcactgctc ccacatgctc aaccttagac aaactcgaag cttgctcaaa
    30121 ggttgaatac atcttagtcg caaatttata ggcgatttta ttggccaagc ccatagacag
    30181 gtcagattcg tgaataaaga caggcactcc tgacacacgc gcagcgataa caggcggtac
    30241 tgagacaaag cccccctttg aaaaaagggt ctgtggacga agtcgcaaca tgataaagag
    30301 cgattggacg attccccagc caactttgaa gacgtccagc atattttgcc aagagaaata
    30361 gcgacgcaat tttccagtcg caatagaatg gaaggtgaca tccaaacctg acttaaggat
    30421 ttcttggtgt tcgataccac gcttgtcccc gatatagtgg acttcccaac catcttcgat
    30481 gaacttgggc attaacaaaa gattgagggt aacgtgtcca accgtccccc cacctgtaaa
    30541 gacaattttt ttcatattat tcttttaact ccgctactgt gtcgataaag aggtcgccac
    30601 gtacttcaaa gttagcatac atatcccagc tggcattggc aggactaaga agaaccacat
    30661 ctccttgagt cgcaagctca taggccttgc gggtcgcatc tgcaatatct gtcgcctcca
    30721 cataagcgac accagccttg tctgctgccc gtttgacacg ttctgcagat tgacccagga
    30781 tgaccatctt cttgagtcca gtaatgtctg gcaccaattc gtcaaactca ttgccacggt
    30841 ccaaaccacc tgcaatcaag acgaccttgc tgttatcaaa tcctgacaag gctttttgag
    30901 tagccaagat attagttgat ttactgtcgt tatagaattt aacacccttg atgtcatcca
    30961 caaactggag acggtgtttg acaccaccga aggctgaaag agtttccttg atggtttgat
    31021 tgtccacacc acgaagcttg gctacagcaa tagtcgcaag ggcattttcc acattgtggc
    31081 tacctggaac accgatttca ttcgctgcca tgactacttc accacggaag tagagttgac
    31141 catcttccag ataagctcca tcaacctttt caagtgttga aaatggtaca acagtggctt
    31201 ctgtcttgga agtcaagtct tttgccaagt cttgattaaa gttcaagaca aggaaatcag
    31261 ctgctgtcat cttgttctgg atattccact tggctgctac atattccgaa aatgacccat
    31321 ggtagtcgat atgagttggc atgaggttgg taataaccgc aatctctgga tggaattctt
    31381 gaacacccat gagttggaaa gaagaaagtt ccataacaag cgtgtcctta tctgatgcta
    31441 tttgagcaac ctgactagct ggatagccga tattccctga taaaagacca tgttgcccag
    31501 cagcagtcaa aacttcccca atcatagtcg ttgtggttgt cttaccgttc gatcctgtga
    31561 taccaataat cggtgcttct gaaatcaaat aagccaattc cacctcagtc aagactggaa
    31621 ttcccttggc caaagccttt tcaatcatgg gattgttgta ggggatacct ggatttttca
    31681 ccataagggc aaactcttca tccaagagtt ccaaaggatg gccacctgta atgaccttga
    31741 tcccttcttc cagcaaactt tgggcagctg gattgtcctc gaaaggcttc ccatcattta
    31801 ctgtcacaat ggcacctaac ttgtccaaca aacgagccgc agattcacca gacttggcca
    31861 aacctaaaac aaggactttc ttatttttaa attgatctat tactttcatg tctcgaactc
    31921 catttctact cctactattt taccattttt atggaaataa aaaagccaca aagtgtgttt
    31981 gtgactcttt cttctaactg aatcttacca tatcatctat gtgataaatc ggtaactcga
    32041 atgacctgat ccacttgctc ccaaatcaga ggattgtggg tcgcaataat aatggtccga
    32101 ttcggatttt ttaaagattc taggatggaa agtaattcct cagagttttt ggggtctaag
    32161 gaagcggttg gttcatctgc gaggatcaaa ggtggatcct ttaaaattat cttcgctaat
    32221 gcaacacgtt gtgcttctcc tcctgataac tcaaatatag gttgcttcaa atccaaataa
    32281 gagaggttta cacggtttag agcttgtttc atcaaagaga ttttctcttt ttccttcaac
    32341 tttttaccaa ctaaacccag attgagattc tctttgacgg tttggctttc aattaagcca
    32401 aaatcttgaa ataagtatcc caagtaatct ctaaagaaaa cagaaggctt gatgtcctta
    32461 agagaagtac catcatagat gatttgtcct ttgtcatatg gctctaatcg tccaatcata
    32521 ttcaagagtg ttgtcttacc acagccactt gtaccgatta aggcataaat tttcccacct
    32581 tcaaaatgaa gattcgtatc tgaaaatagc tgacggcttc caaatttttt agatatattc
    32641 tttagttcaa tcatcctatt ttcctttcat aattgtcata gaaacacgag attctttctg
    32701 cgcttgacgg taaagcgtca aaactgcact agctagaaag acgaataaag tgagcaagcc
    32761 aatcaccaag tctcgactgc ttaaaataaa gaaactagca ccaaatacaa aactggcaaa
    32821 ttggctaacc atatactgag catgtgtttc aaaaaatcgt aaacctgaaa ttcgtttaat
    32881 caagatatct cggcggaatt gctcgaaata tagaagattg acagaataaa agagtaataa
    32941 ggaactggct atcccaacaa tagctcctaa gattaaagtt gctgtttcag tttgaacttc
    33001 attataacga gttagataaa cacttcttcc ttctttaaga taggatactt gctcataaat
    33061 tccagctttc tttaagagtt ctagcccact ctcatatcct ttgataaaga gttgttttcc
    33121 agcattgata gaccaaacat attttgaaat gaaactatca cctgtagatg ttggagtaaa
    33181 tacaactaaa atcggatcgg ttaagtactg aatagatact ggactttcac cgttattata
    33241 aacaaagcgt ttttgtcctg ttggaagata gctaacaatc gctctcattt catactctaa
    33301 aggagcgtct ttatcctcgc ttgattttcc gtaatagttc aaacgttctt caaaaacttt
    33361 cttaagttct gcttcctgtg aacgaagaga ttctggtaat aagagtccaa attccccttt
    33421 ttgaagatga gctagtttct gtctagtctc atcatttaca gccacatttt ccttgtctaa
    33481 ataacttgga ctcacataga gaacattagc atctggacta taggtatcca gtgtttcccc
    33541 gttttcattt tttccttgag gatttgcaaa atgaatgaga ttctctttta caaatagagc
    33601 ctgttctttt tcaactgctt ctttggaaaa ttcataccac ttattctgat tttctgtatc
    33661 atttactctg tcacctaagc caaaagaaat ttgataatag tctactctgt catgccatgc
    33721 ttgttttgaa atttcaagtt ctttcaatcg ttggtaagac gtcaaacctg tcttaacagc
    33781 gtatcccact gtaaagacag caaccaactg acacaatagg gttaaaatca tcaggcgttt
    33841 aaggggtaat cttcccttaa taacgggaac taatgctttg taactcaaac tcattagata
    33901 aaggagcatt agtaaaattg aaatcgccaa taaaaacaac agatagaaac taatcccaaa
    33961 accataggtg gctaacaaga taggataaaa caaaccttga ctaaaaagaa cgactccccc
    34021 acctaggaag gaaaggaggg ctgatagaag gagccactta atatcagtag ataaagaatg
    34081 ccccataatg gataagagag tctgaccaga aaagagtttt atacctgctg ctctcatttc
    34141 cttaatccga gtgataatca ctaaagcaaa gaaagataag ccaaatattg ctaaactaat
    34201 taaaataagg ggatttagta acattcgaaa agcaagagaa tagggaggtg tctttcggtc
    34261 agcaattgct ttataaccta aatctcctaa tttatcagct agcttttctt ttgtcaagga
    34321 gcctgataaa aggagataac tatttagcgg atcactacgt tcacgacttt cttggctagc
    34381 ttcttggaat tgttttggta atgttccctg accataagtt gcataagtaa agtgagtcgt
    34441 cccatcctta ctcggttcta caattctcct agctattaaa ctctgttctg agtttacaaa
    34501 cttctccaat tcctgttcaa atacctcacg agtcggttcc tgagcctctt ttttgacacg
    34561 aagtaaagta acggaatcat agcttgcata taaatattgt ggcgcacgta agacaataat
    34621 ccaagcaaag aagaagctga gaaaaaaagt tgatagtaat atgaatagtt tcttcatagt
    34681 agactccttg taaacaaaat tccccctgta atttcttaca aggggaatta tctaagaaaa
    34741 ctaaatatta gtcatagtca tagtaaaatg atacttgttc cccaaattta gtccaaatcc
    34801 aagcctctga agttttccct gcaggtgctg atcctttatc tgaatgacta tcccatttac
    34861 ttacaacaga agaataatga tattttttac catgatagta atttgaaaaa gcccaaccac
    34921 ctcctgaacc ttctccatat gtccatactc ctccatctgg atattgtaca gcagctgatg
    34981 cagctcccaa taatgtaaag cttgaaataa gagctagagc aagtaatcta tgttttttcg
    35041 ttttcatttt atttttcctt tcaaaaaaag cacaccctga gcaacaatgc aacaaaataa
    35101 atcctcctct ctcttttttg aaaccgattt cttatataat aagaatagca tttttattat
    35161 ttgttgtcaa ggaaaaaatc gaatttttta gatgttttac tatattatct ctatgaataa
    35221 tattatatag tagttttatt ttaaaataat atgcaaccag tactaaccaa atataaaata
    35281 gatgccatta acgaatttta ttcaagtttt tcccattcat actatacaag caaaagagat
    35341 ggtgttaact aaaaagcaat tcaaactatt ataaaattcc tagcaaaaag agagccgaaa
    35401 ctctcttttt tatcttcttt tacttttttt gactggcatg agtgtgatgt ctctaacact
    35461 aaagtaagct aggatcaaca tggctattgc taggaatatt tctgttggta attgaaaaat
    35521 tttcagaaaa gatagaacca ataaaatcaa gagtgccact aaaatacata ccatagcgac
    35581 gatattgact gtccctttaa tgctttctgg tgtcgcaaat acatagagta ggagcagtaa
    35641 aattcctagg actaaataga ccatctttct ctctttctag ctcttattca gctgattttt
    35701 tcttcttgtt agctttctca cgctctgctt tgttaaggat ttgtttacgc aaacggatag
    35761 actcaggcgt tacttccatg tactcatcgt cgttcaagaa ctcaagagac tcttcaagtg
    35821 tcaagatacg aggcgtcttg ataacagctg tttggtcctt agtagctgaa cgaacgttgg
    35881 tcatttgttt tgccttcgtg atgttaactg tcaagtcatt ttcacgagag ttttcaccga
    35941 tgatcattcc ttcataaacc tcagtacctg ggttgacaaa gatcgtacca cgttcttcga
    36001 tagacatgat tgagtaagtt gtagccttac cagcatcgat agaaacaagg gcaccacggt
    36061 gacgtccacc aatttcccct ggaatcaatg gcaagtattg gtcgaaggta tggttcatga
    36121 taccgtaacc acgagtcatt gacaagaact cagttgagta tccaatcaaa ccacgcgctg
    36181 gaacaaggaa gaccaaacga gtttgaccat taccagttga aatcatatcc aacatttcac
    36241 ctttacgttc agaaaggctt tggataacag acccttggta ttcttctgga gtgtcgattt
    36301 gtacacgttc aaatggttca catttaacac cgtcgatttc ttttacgata acttctggac
    36361 gagatacttg aagttcatag ccctcacgac gcattgtttc gataaggatt gacaagtgca
    36421 attctccacg tcctgaaaca gtccatttat ctggtgaatc agttgggtca acacgaaggg
    36481 aaacgtctgt ttgcaattct gcctgcaagc gttcttccac cttacgagaa gttacccatt
    36541 taccttcttt accagcaaat ggtgagttgt tgaccaagaa agtcatttga agagttggct
    36601 catcgatgtg taggattgga agagcttcta ctgcatctgt cggagtgatg gtttcaccga
    36661 caaagatgtc ttccatacct gaaacggcaa tcaagtcacc cgctttggct tcttggattt
    36721 cacgacgttc caaaccaaag aaaccgaaga gttttgtaac acggaagttt ttagttgtac
    36781 cgtcaagttt agaaagggta acttggtccc caaccttaac tgtaccacgg aagacacgac
    36841 cgataccgat acgtccaacg aagtcattgt agtccaaaag tgacacttgg aactgcaaag
    36901 gctcatctga gttatctact ggagctggga tatggtcgat aatcgtgtca aagattggtg
    36961 ccatagtcgc ttcttggtca gctggatcat ctgacaatga agaagttccg ttgatcgctg
    37021 aagcataaac cactgggaaa tcaagctggt cgtcatctgc accaagctcg atgaaaagtt
    37081 ccaagacttc atccactact tctgctggac gagctgatgg cttatcgatt ttgttaacaa
    37141 ccacgattgg gacaaggtct tgttccaagg cttttttcaa tacgaaacga gtttgtggca
    37201 tggttccttc ataggcatct acgaccaaga caacaccgtc aaccattttc atgatacgct
    37261 caacttctcc accgaagtcc gcgtgtcctg gtgtgtccat aatgttgata cgagttccgt
    37321 tgtaagcaac ggcagtattt ttagcaagga tggtaatccc acgctctttt tcgatatcgt
    37381 ttgagtccat agcacgctct gccaattcag tacgtgcatc aagcgtttct gattgtttca
    37441 ataattcgtc aaccagggtt gttttaccgt ggtcaacgtg ggcgataatc gcaatgttac
    37501 ggatatcttc tcttaatttt gtcatgattt cctctataat attcaaaatt tattttctaa
    37561 ctgaacgatt ataccataat ttcaaataaa taacataact caagcaagtg taaatgtttt
    37621 cactccgctt ttcttttcac gtcaagcctt ttcaaagcaa gcgacttatg ataagatagg
    37681 cacagtatgc gtttagataa tttattagct caagaaaaaa tcagccgaaa ggccatgaaa
    37741 caagccttac tcaaagggga cattctcgtc gatagttgcc cagcccgatc cctagcccaa
    37801 aatatcgata caggactaca agaactcctt tttcaggatc gaatcattca aggctatgaa
    37861 cacacctatc ttatgcttca taagcctgct ggtgtcgtta cagccaacaa agacaaggaa
    37921 cttccgaccg tcatggacct gcttccatct gacatccagt ctgacaagct ctatgccgtt
    37981 ggccgactgg accgagatac aacgggactc ctcctcttga ccgataacgg tcccttgggc
    38041 tttcagctcc tccatcccca atatcatgtc gataagactt accaagtcca ggttaatgga
    38101 cttctaacac ctgaccatat ccaagccttt caaaagggaa ttgtcttttt agatggtact
    38161 gtctgtaaac ccgcaaaact agagattcta tctgcaagtc cctccctcag tcaagcctct
    38221 atcaccattt cagaaggaaa atttcatcaa atcaagaaaa tgttcctctc ggttggtgtt
    38281 aaggtgacta gcctcaaaag aatccaattt ggggacttca cattgaaccc agatttagca
    38341 gaaagtaact accgcccttt gaaccaaaaa gagttacaaa tcattaaaaa ctatttagag
    38401 atgagtcgat aaaacaaaaa aagctttaaa actaaagctt ttttctttta tttaccgaaa
    38461 aattaaggcg attgctacaa tccagttaac tacagaaatc acaattccta agatattaag
    38521 aatcttttct attttatagt ctaattgtga ctctttttgg tatgaaatag ccaagaccaa
    38581 tcctatgata cccaaaatca ggcctacaat tggaaataac aaaccaagaa taatcgacaa
    38641 gatacccaca aaaagtggat ttttcttctt ttctttcatg ttctaagaac tctttaaatt
    38701 ttatacaaat taattatact ataaaacaat agcttcatcc tatcattcga ctaatttgga
    38761 aataaggtta gctagtcttc actttccctt tccaagaatc caagccataa gaaaggatat
    38821 aaatctcaga aaaaccttgt tttttcaagt aaagagctgc atttgtaact cgttgcgcac
    38881 gttggttctc gtagagaagg acaggtttat ctttacgaag ggctgcaaga ctagttttca
    38941 actgacttga aggaatattg cgtgcaccaa ggatatgttt tctgtggaat tctgctgggt
    39001 cgcgcaaatc aatcaattga cccgtacgaa tcaaggcttc aaactcctca ttgtccacaa
    39061 ttttagccgc acgacgaata cgaagatagt taaagcccat ccacgccaac attgctagta
    39121 taagtgccca caaaatccaa gtaaccatta gttcttttct ccatttttct caatataatc
    39181 caattctacc ttgtgctctc tgcgaagaac tgcttctgcc tctagatagt ctaatttatc
    39241 catcaaccct gcatcgtaaa tccgagatag ttccaacttc atcagttcaa tatcatataa
    39301 gcgttttccc atgtaaacaa taataccaaa tcgtttgagg aattgctgca catcatagaa
    39361 tgttttcata agactcattc tagcaaaatt ttgtgttttt ttcaagaaga gactcacaca
    39421 atgctcctta ttttcctatc ttctttggcg attctaaggc aagtgtggta caataaaaac
    39481 atgagaattc aacaattaca ttatattatc aaaatcgtcg aaactggctc tatgaatgag
    39541 gcagccaagc aactctttat cactcagccc agtctctcca atgcagtgcg agatttggaa
    39601 aatgaaatgg gcattgaaat ctttatccgc aatcccaagg gtattacctt gacccgtgat
    39661 gggatggagt ttctctctta tgcccgtcag gttgtcgagc agacccagct tctggaggaa
    39721 cgctataaaa atcctgttgc ccaccgcgaa ctctttagcg tttcgtctca acactatgcc
    39781 tttgtggtca atgcctttgt ctctttgctc aagaaaagcg atatggagaa atacgaactc
    39841 ttccttcgtg aaactcggac ttgggagatt atcgacgacg tcaagaactt ccgcagtgag
    39901 gtcggggtcc tcttcttaaa cagttacaac cgtgatgttt taaccaagat gctggatgac
    39961 aatcacctgc tatcccacca tctcttcaca gcgcaaccgc atatctttgt cagcaagacc
    40021 aaccctctgg caaagaaaga caaggtgaaa ctgtctgatt tggagaattt cccttacctc
    40081 agctatgacc aagggacgca caactccttc tacttttcag aagagattct ttctcaagaa
    40141 caccacaaga aatccattgt ggtcagtgac cgtgccaccc tctttaatct cttgattggt
    40201 ttggatggtt ataccattgc gacagggatt ttgaacagca acctaaacgg agacaatatc
    40261 gtttctatcc cactggatat tgatgacccg attgagctgg tctatatcca gcatgagaaa
    40321 accagcctat ctaagatggg cgaacgcttt atcgactatc tactagaaga agttcagttt
    40381 gatagttgag aaatgataag aaccaatatg taggctagca acaacctgca cattggttct
    40441 ttttacttat aattaaaagt ttcccctgcc aacttatcag ctagcttggg aaagagagta
    40501 taaaacttat gggctaggtt caacaaaatc gggagattga gttctcgttt attttttcct
    40561 ataatcttga caatcttttt agccactgca tctgcctcta agaggaagcg gtcaaccgat
    40621 ttaagataag ttccatctgg gtcagcttgg tcaaaaaatc ctgttcggat tggacctgga
    40681 ttgactgttg tcacatagac tccatagggc ataagttcga gtcgcagagc atttgaaaaa
    40741 ccaatagccg caaacttggt cgctgagtaa agactagact tgccagtagc tattagacct
    40801 gccatgctga cgatgttgat gatatgccct ttgctgcttt ccttcatacg agccgcaagg
    40861 tgacgagaca gattcatcag ggcaaaggta ttgacctcaa acatctggtg aatgtcttta
    40921 tcagcaattt ggtcaaatcc ctcaaaaatc ccgtaaccag cgttgttaat caagacatca
    40981 atcttgccat agcggagata aagatcagtt accagagctt ctagggctga atcgtcggta
    41041 atatcaattt caatcaattc tgcatgggaa taatttccgt agagttgggc taatttttcc
    41101 ttatttctac caagcaagat gagttggtca ttgggcagga gtttgaccat ttcttgagct
    41161 agaccaccgc tagctccggt aatgagaata gtaggcatac ttatcctttc tgtgactgct
    41221 agatttccac ttcttccaag tctttgacca catggacatt ttcaaaaatt gtggcagcgt
    41281 ccttcttgag tttgcttata tcttttgaga ggaaacgggc actgatatgg ttgagtagga
    41341 ggcgtttggc acctgcttct accgctactt gtgcagcttg catattagtt gagtgaccat
    41401 ggttacgagc aattttttca tcacccttgc cataagtgga ctcatgaact aggacatctg
    41461 cattgacagc cagacgcaca ctggcatccg tttttcgagt gtctcctaaa atagtgataa
    41521 tcttacctgg acgtggcgct gagatatagt ctgctgcctt gatttcagtt ccgtcttcca
    41581 aaacaagatc ctggccgttt ttgattttac caaaaagcgg gccgaacgga acaccagcag
    41641 ccttgagttt ttcagcatcc agcgtccctt ctagatcctt ttgcatgaca cgatagccaa
    41701 cacagaaaat agtgtggtcc agctcctctg catacacagt gaatttatcg gtttcgagaa
    41761 ttttacccag agaatcttgg tcaaactcat ggaaatgaat gcggtagggc agacgagaac
    41821 ctgacacacg aaggctggtt aagacaaatg acttgattcc ttgaggtccg tagatttcca
    41881 aatctgtctg ctcttcattg gcctgaaagg cacggctaga aaggaaacct ggcaaaccaa
    41941 aaatgtggtc tccatgcaga tgagtaataa agattttgct gaccttacgt ggtcgaattg
    42001 tggtttccag aatgcgattt tgcgtacctt ctccacagtc aaagagccaa acttcgttaa
    42061 tctcgtccaa aagtttcagg gcgagacttg aaacgttgcg ggctttagag ggctgaccag
    42121 cccccgttcc taaaaattga atatccattc gatactttct aattaatcaa tatataacat
    42181 ggctgtgcgg ttttccgatc ggaaatagcg tttgccagaa aaagcagcag cttcttgcaa
    42241 taaatcctct tggctgtagc ctttgagacg ttttcgacca tcagccaatc tttccaaatc
    42301 agtcaaagct gtgagacttt ctaggctgac aacttcctcg tcctcgacag gcttcatgta
    42361 aatcttacca gactcttcaa agactaattg atgggggaaa atttgcgcaa tttcaaagag
    42421 caagtcatcc gagattttct cctcattttc agagaaaatc cgaccaaagc cgtcactctc
    42481 ataacaaaaa ccaaaggatt taccagacag attaagccga ataaaagact tattttctag
    42541 ggtgaaactt ggctcagtat tgtaaagatt cagttcctga ctgagttctg caaaataatc
    42601 cgtcgcagcc tgaggacttt ttttctgata gagttctgca aagtaggcat taacaacact
    42661 tggcggaggt gtaataagtg ttaactgctc ctgctctgtc ttaccagcta gaagctgatc
    42721 cagatagacc ttgtccagac ttgtataacc tccatacttt agagccaaag ttttaatatc
    42781 agtcataaaa ttcttctaac ctccatttat ttttctcgga aatgtagcct gtaatcactt
    42841 cgccgtcttc ctgataatca cgttcttcca gaattgcaac actctctaaa tcatgaatct
    42901 tgtaggactt tgaaaaaggc actcgcaggg taaatgcttc aaaaatttcc ttaatcttat
    42961 ctagcaataa tgcttgcaag ttttcacgac tgtcctcaga cttggcagaa atgagggtat
    43021 atggcgtttg ggtaggcatg aaatcctcca ccaaatccgc tttattataa agcgtcaagt
    43081 gaggaatatc ttccatgtcc aggtctttca tgatggagag aaccgttttt tcatgttcct
    43141 cgtggtaagg attgctagca tcgataacat gaaccagaag gtccacatgc ttgctttctt
    43201 ccaaggttga cttgaaactg gacaccaact ctgtcggcaa atcttggata aagccaacgg
    43261 tatctgtcaa agttacttgg aggttgcctc ccagatgaat actcttggtt gtcgcatcca
    43321 gagtcgcaaa gagctcatct gcttcatact gggtcttact ggtcaagatg ttcatgatag
    43381 ttgatttccc agcattagta taaccaatca aaccaatctt aaaagtgcta gactccaaac
    43441 gtttttctct gacagtcgca cgatttttct caaccacctt aagctggcgc tcgatatccg
    43501 tgatttgatt gcgaacgcta cgacggttca gctccagttg gctttcacca ggaccacggg
    43561 aaccaattcc ccctgcctga cggctgagca taatcccctg accaaccaag cgaggcaaga
    43621 ggtatttgag ttgggctagg tggacttgga gcttcccttc atggcttcga gcccgcatgg
    43681 caaagatatc caaaatcaac tgcatacggt caatgacctt aacaccgaga acttcctcta
    43741 gattgacatt ctgccttggg gtcagacggt tgttgacgat gacagtagtg atttcttctg
    43801 catccaccat aagcgcaatc tcttccaact taccagagcc gacgaaggtc ttggaatcat
    43861 atttttcacg tttttgtctg tagctatcta caacgactgc ccctgccgtt ttcgctaaac
    43921 tagccaattc ttccatggag aggtcaaaac tgtccatacc ctgcaattcc acaccaatca
    43981 gcaggactcg ctcctctttt ttctccgttt caatcatcta aaaactcctc tatctggctt
    44041 aaaatgcggt cttgtacacc agattctcca atctgataaa aggtgacctg catgcgatta
    44101 cggaaccagg tcagctgacg cttggcaaaa cgacgggtcg cctgtttaag actctcacga
    44161 gcttcctcca aggtctgctc tccacggaaa taaggaaaga gttccttata gccaattcct
    44221 ttagcagcct gtacattagg ggaatggtca aacagccact tggcctcatc caaaagccca
    44281 gcctcaaaca tcaaatccac tcggtggttg atacgctcat aaagttgact acgttcatca
    44341 tccaagcaga taatcagcgg ttcatacaaa atctcttgat tttccaaatc ctgaccaaaa
    44401 tgggcaattt ctaaggcacg catagcacga cgacgattaa actggggaat ctcaaggcct
    44461 gcttgctcca ccaaatgggc taattcctca tctgaatatg gctccaaact agctcgataa
    44521 gctaaaatct cctcatgagg agtctcccca cctaggtggt aaccttctag caagctctgg
    44581 atataaagtc cagtcccacc ggcgataatg gctagcttgc cacggttgtg aataccctca
    44641 atagtcatct tagcttctga aacaaaatca aaagccgagt aagactcggt tatctctcta
    44701 acatcgatta aatgatgagg aacagctgcc tgctcttctg gactagcctt ggccgtccca
    44761 atatcaagtc ctcgatagac ttgctggcta tctccactaa ccacttcgcc attaaaacgc
    44821 tttgcaactt caatagctag agccgtcttt ccaacagcag tcggtccaac aatcacaatt
    44881 atttttgttt tcatcttttt tccttgaaaa attcccattt tttcgttact attattataa
    44941 cacaaaaagg tcagtcagaa aaatgtgacc tcttgaggag gctggctgat tgagaatata
    45001 aaggaggaag actcatggct aaaggattcg ctaaaggtct tgtaacaggt gtcgcaggaa
    45061 ctgtcgctgc cgttgcaggt gcagtatacg catttaaaaa gaaagtaatc gaaccagaag
    45121 agcaaaaagc agctttcatc gaagaaaacc gtaaaaaagc agctcgtcgc cgcgtatcac
    45181 gttaagaaac aaaagaagtt gggattattc tcaacttctt ttttctattc ttttaaatag
    45241 ctaggtcaaa cttcaactgt ggcttaacag ggtcataatc caccaactca aaatcttctg
    45301 ctttgatatc aaagaaatta gtcccatcag gaacatttaa aaccaagcgt ggttggcagt
    45361 ttgacggctc ccgacggagc aattcctgag cttgttcaaa ttgattatca tagatatgga
    45421 ggttgttgat gaagtagaag aacttcccaa ccttccagcc aaaatgtttg gcaatcatca
    45481 tctgcaaagc cacatactgc atagcgttga tgtggtgggc caccagcata tcattggagc
    45541 gctgggtcaa ggtcgcatcc agatagattt ccccatcaac acgccggaca tcaaacatgg
    45601 tctgaaaggc gcacgggagc agcccatctg tttcttcgaa agcttggtaa tcccagagcg
    45661 aaataatatt gcggcggttc caaggattgg tttccaactg tttgagaagc ttattgataa
    45721 tgtcgtgttt cttaacaacg gcaccatagc gctcaccaat ggttcccgtg tctccaactt
    45781 cccagtcatt ccagtagtga acattgtact tgtcattaag cacttctaag ctatttgact
    45841 ggtcttggta aatccagaga acttctttga tggcggattt gattgcaatg ggacgcaagg
    45901 ttgtgatagg aaattctcct ttagataagt cgtactcgga aaaggcacca gttacatact
    45961 tggaattagc aacagtccca tccttgtact taggacgagc ctgctctgag aaaacacctt
    46021 cctttagaat gcgttcaata ttctctttaa aaatcgtatc tgcttttgtc atttcgtttc
    46081 acctcattca ttgtcctaac tagtatagca taaaaaataa aagaggaaca ttactaactc
    46141 taggttagca ttttcctctc tcattatctt attgcaatac aagtgatgct gctccgataa
    46201 ctccagcgtc atttcctaga gttgcaagag ctaatttagt agatgtgcgt acttgtggga
    46261 aactattttc atcgtaaact ttttgaacac cttgtagaag gaattctccc gcagctgaca
    46321 caccaccacc gatgacgatt gttgatgggt ttaggattga accaatgtta gcacaagcga
    46381 ttcccaagta acgtgagaag ttacggtaaa caatcaaagc aaggtcgtct ccttcttttg
    46441 cgagatcaaa gacagtctta gcagttactt cttctccgtt atcaatcaag cgtttcaagg
    46501 ctgcatcgcc ttcgtattca tcggcatagc gacgagtcaa gttgacaatc cctgttgctg
    46561 aagcaactgt ctcaaggcag cctttcttac cgcaagtaca tgcgattggc tggtcaaagt
    46621 caacagtgat gtgaccaagc tcacctgctg caccagcaac accgtgaagc aatttgcctt
    46681 ctgcgacgat accgccacca acaccagtac cgagtgtcat aaagacaacg tctggttggt
    46741 tatctccagc acccatccag cgctcaccaa gagctgctac gttggcatca ttatcgatga
    46801 aaaatggaat gcccaaagct ttttcaatct tttgtttgat tggttgaagg gttttccagt
    46861 tcaagttgta ggcaccgata acagtccctt tttcacggtc aaccacacct ggtgatccca
    46921 ttccaatgcc ttggaagtcc gctgctgcca atccaagcaa gtccaaacga tgttgaatag
    46981 actcaatcat atcatcaacg atatgacttc cctcatccaa aatgtttgtc ttgattgacc
    47041 attttccttg gatttctcct gctgttgtta agattgcaaa tttgatagaa gttccaccaa
    47101 ggtcaatccc aataatcttt tgactcatca tattctcctt tttcattgtg tagtaattga
    47161 aaatgcttac agtactagta tatcaaaatc cattcactta tgcaaaggtt tgcgtaaatg
    47221 aattataagg aattttttcg cctaccagta tctgttaatc atctaaatga tcaatggcat
    47281 attgagctgc atcatttgaa aatttatcaa aatcagaagt taattgtcta tacatacgtt
    47341 tttttgacat gtggaataac gaattataac tttttgcctt tcctaaagca gcagaatatt
    47401 cactattgct atcattacta gaagaaactg tacttgcttg accttccttc caaactccgt
    47461 cagcgccaac ataataacgt ccaccatcaa cccattcatt gacagccatt ttaccattcg
    47521 attttagata gtaatttcct tgccatgtac tgtaagcata agaaccatct gatgtcaaat
    47581 aataccaagc ttgataggtg gcatcataaa cccattcacc tttagccatt ttaccatctg
    47641 atttcaaata gtagtttcct tgccatgcat tgcgagcata tgaaccatct gatttcaagt
    47701 aataccatgc ttggtaagaa gaatcataaa cccactcacc ttgtgccatt ttaccgtttg
    47761 atttaaggta ataagctcct tgccatgcat tttttgcata agaaccatct gatttcaaat
    47821 aataccaagc ttgataagaa gagtcataaa tccattcact ctgtgccatt ttaccatcag
    47881 ctttcaggta atagcttccc tgccatgcat ttttcactag atttccattt ccatcaaagt
    47941 agtaccaagc gccgtcctgc ttaacccaac cacttgttgt tgctgaactt gtgttgattt
    48001 gaatagccgt tgactgtttt gctttaaaag cacccttagg agcatttttc aattcgcaag
    48061 ccacaccatc atgatcacgg tctaacttgg cagaataacc aggttctccc tcgtgaatat
    48121 ccgaatagcc attcgcccaa gcttccttac agctcgaaaa atggatgttt tcttccgcca
    48181 aaactggttg tgaaaacaag gctaaaattg gcaacgtcac cagactcatt tttaaaaata
    48241 gacgtttatt catttctttc tcccataatt atgatatcga tttcaatatt attttatcaa
    48301 acttatttca gcaattcaag gaaacttctg gtcttttcta caaactcctt tggttttgcc
    48361 ttattcaaga catgagggcc atcaggaatg atctgaaact gcgaatctgt taacagtcta
    48421 tggagagctt tcatagaact aagattcggt ttatctttgc tgccacaaat tagtaaggtt
    48481 ggataggagc aagtccctgc tatatccgtt aaatcaagtg tcttcaattc ctcagaaact
    48541 ccgaccataa gagtcttgtc tgctccctgt ttttcaaata ctcttttggg aagtagttta
    48601 aaaatcagca actgaagata aaataggata ttccctgcta atttaagcgg gcatcctgac
    48661 agaatcaaag ctcgaagatt tggtaaatcg taactggaaa gttctagtgt cagggcagca
    48721 cctaaggaca atccaatcaa aacaaaaggt tctgtctctt gagctaggtg ctgataaact
    48781 cgctctttag cttgttgata gttactaact ccagaaggaa ataactcgat agcctcagaa
    48841 ggataatctg tcagtagatt ccgaacttct ttccaagact ctgctgactg ctctaaccca
    48901 tgcaaaaata tcaatttcat ctagttctcc tcaaggctta gttcatacaa gcctctcact
    48961 gcattacagc cgtaaatagc ttctgcttgg gttaaatctg ccaaggtcaa gactttctct
    49021 tctacctgtc ctgtttctag caaatgctga cggtaaattc ctggcaagat tccaagtcgg
    49081 ataggcggtg tgtagagttt tccagcgatt ttcagaacca aatttcctat agaggtttca
    49141 agcagttctc ctgacttatt gtggtaaatc ttctcttgtt ctcctaggct caaatgcggt
    49201 cggtgagtgg ttttaaagta ggtaaaggat tgattcaaag cagcttcctg aaggcagact
    49261 tgggcctgac aaaagcttgt actgagaggg gttaatactt gacgattgac ttctatctct
    49321 ccagatttgc taaggctgat tcgcaagcgg taatcttgat tagcttcaca atcctgacac
    49381 tcttcctcaa tcttgtgtcc caagtcttct gcatcaaaag gaaaggcaaa ataacgacta
    49441 gcttttctca gtctttccag atgttgatct tcaaacagca ggttcttctg gctgatttcc
    49501 cctgtcgtaa tcagttggaa gcgagcttgt ttacgataaa gaactgctgc cttttgatga
    49561 acctctcggt attcagattc ccatgtgcta tcccaagtaa tccctccgcc aactccataa
    49621 atggcttgac ctttgtgaag ttgaatggta cgaatggcca cattaaaaat ccgtcgtcca
    49681 tttggaagca agagaccaat cgttccacag tagactccac gcggttgagg ctccaagttc
    49741 ttgataatct ccattgtcgc aattttcggt gcacccgtta tggaaccaca aggaaagagt
    49801 gagcggaaga tttcaacaag gtccacatcc tctcgcaact gactcttgat ggtcgaagtc
    49861 atctgccaaa cagttgaata ctgctctacc tggcacagac gctccacgtg ctcgctccca
    49921 acttcagaaa tacggttcat atcattgcgc aagaggtcca caatcatcat attttcagag
    49981 cgatttttgg gatcctgttc caaccaactg gcctgttcaa gatcttcttg gtcagttacc
    50041 ccacgctgag tcgtcccctt cattggtcgt gttgtcaact cgcgatcatt ttgctcaaaa
    50101 aagagctctg ggctcatgga aatcactgcc atctcgtcat gttccacata ggcattgtag
    50161 cccgcctcct gctctaccac catacgattg tagatggcaa aaggattggc acttaacttt
    50221 tgcttgagtt ggacggtgta gttgacctga taggtgtctc cctgcctcaa gtgatggtgt
    50281 atctgggcaa tggccttttc atagtctgct gcagacgtca cttcctgcca atttgagggc
    50341 aaatcaatat cctcataagt cagaggaata ggggaagttt ctacgctatc atgaacagta
    50401 aagtaaagca ggtactctcc cagtagggga tccttgtgaa ctgctaattt ttcctcaaaa
    50461 gcaggtgcag cctcgtagct gacatacccc accacataat aaccttgctc ttggtagctt
    50521 tccacttgtg ccagcaaatc tgccacttct tctacatttc tcgttttcaa ctctttaata
    50581 ggctgggcaa aggtatatct ctcccctaaa gtcctaaaat caatcactgt ttttctatgc
    50641 ataccttaag tatagcataa aaaggcagat acagacaaag ctgatctacc tttttacgat
    50701 tttattcatt ctatgcttgt ggtgcagtaa atagatcacc agagaaaccg tctgtgtttt
    50761 taaggagaga tttaaagact ttcgatttca agacaactgt atttcggtat ttgtctttaa
    50821 tactactatc gtttagttcc gttaaatctt tagtaacagc ctcatcaaac atagtcttca
    50881 actgttcata ggttgaaatt tgagtgccat taatttcaat tggtgcaaaa ccttttttag
    50941 attttgtaag aacttcccca taccattgct tcttccaatc ttcaaggttt gaaaattggt
    51001 tattagaaac tttcttaata atgaaatcat cacctaatag accgttattt tctttattgg
    51061 ctgcaccttg atgtttgctt gaaacatagt caatgaaccc atgttcatat ccatagtaac
    51121 cccacatacg gaaggcgtta tgtttgaagg atagagaacc aggggcacct tgactcgtat
    51181 taccgccata aataccagcc atcatattaa cattgacata tgccgtacca aagtcctctg
    51241 ggtggaagac cttattacct ggatttccgt gaatggtcat gaaattatta tttaccaagt
    51301 catcgatggt ttcaaggtta gttgttttct cagcgtctat caaatcacgc actttgtccc
    51361 attggtgagg accacttagt ttatttctgt ccattggtcg acgtgtttcg cgatcaattt
    51421 tcttgaacca cttactattg tcacctttaa ccttaggaag aacagcctca gcttctgcat
    51481 aatcgagcat catcatagct tcattgtagt tcttcatgta atggtcgatt tggtcacgtg
    51541 tttgaagttt ggtaggatct ggattatacc attggtttcc atcatttgaa cgttcaaatg
    51601 ccatatttaa tccaagtgcg ccatattcac cttgatgtcc atgttctgct ggagtttgta
    51661 acataccttg agcaaatgct tcaagatctg taccctgtcg atgtctatga cctcccagat
    51721 atgccattcg gtcatttacg tgggtagtct catgtgtaaa ggcagatgtg ccatattcac
    51781 ttattaaatc cgacataaca aaatatacag catccatagg ctgtggatca gcaaagatgt
    51841 aagcatacgc tccataccca tacttataat catgatactt atcaatacgt ccaaagaatt
    51901 cacgaatagg tgcataatcc ggtttatctt ttcgatgacc aaatctatca ggccaaccac
    51961 cgggtgcacc atgattatcc catacaggag ttggaactac attttgactc ttaagaagtt
    52021 tatcgcggac attatcagtg gcaaggcgtg accaaaaatc taagtaatta acttgctctt
    52081 tagcacgttt attgatttca ctcttgaacg cttcacgttt ttcttctgta tctttaccat
    52141 acttttcaaa cgaactaaat gagatagtat tatatgttga aatcataaat aaatgtgcat
    52201 ctttcaagtt cagaagcgat aaaatcatgc gtccatgttg tccgttatta agtccttcat
    52261 atagacgata ttttttatta gcaaatgcag ggttagttga cggttgttca actacataag
    52321 cattattttc aatagctttc ttaaaccaaa catttatgtc tgtttcattt gtgaatagtt
    52381 tcatattgta ggtcaagaag tcatgtaagt ttccagaaag agtatttttc gccaccactt
    52441 cacggaagga ctcctgtgta cgacttccct taatatagtc ctcttttgaa ccaatttcta
    52501 ttaatcgatc taaaacactt acattcttac cataaaaatc tggtttgaat agcattaatt
    52561 ctttaatatt gaagttatca aatttcacac cgtaataacg atttaggtat gttaatccta
    52621 acaggacagc agctttgtta tcttcaattt tcttaatcaa ggcacgtttt gcagcttcat
    52681 ctgtattcag ttgatgatct tcattttcaa ctaattttgt cacaaatgta ttaagatgat
    52741 cttttacttc tttaaagctt tcttctaagt aaagattctt aattgcatta actctgttat
    52801 ccccagttct tcctaatcgt tgataaattg gatcagattg taattcaatt ggacttaaaa
    52861 taccttcaat agcactaatt aaatctgcac gatctttaac aaccatattt ggtgtataga
    52921 cgacttcacc aagctctgcg acactgtatt cttttacttg cttaacttga gagtctttag
    52981 gagaaatcgt aaagatatct tttgtcttat ctgcgtaatg aaccataata tggtcagcat
    53041 ctgtaaggtc tgtaataaag tcattacctt tcattgcagt cacagacaat acttctttat
    53101 tcattaatgg actatcagtt gtaagcttgt tcccttgatt cacaatccat tctttgttgt
    53161 agaacggttg gagtttttca acattacgat aaacaagctc acgatttgca ttataatctt
    53221 gaattgtttt gtattcttca tcacgtaata tacggcgatt caacttatca accaaatgct
    53281 cagttacttc aaatgtatca gcagtgatac ccatatcctt aattttctta tcagcttcta
    53341 cctgtgaaat ttctttaatt ttagacgatt gtttatgggt tttatctcca gaactcacac
    53401 cgataactgt tgcattatta ggtttaatcc aattgcttac aaattcatca tccatatcat
    53461 tagaaccaaa gaaaatatca ccacgcttaa cattcactaa gctgatattg ttatcaatgg
    53521 ttccccaagg ccagtcttta ccaattaaac cgcctacatc acctctagca acatcaatag
    53581 tacctttggc tacagaattt cttacattag accaagcacc aacatctctt ggattaaaat
    53641 catgagctaa atgtcctact atagcacctg cacgagtatt taaaccttta agttcaacat
    53701 ctgcataagc tttatttaaa ttgcctcgat aaatctcaga tgcaatccca gccaagttcc
    53761 accctttatc accaacagat tgaacttttc cgataaaagc aacattagtc ataatacctg
    53821 catcatctaa tttatccaaa atacccgcaa cattgttatt accaacgata gtacccgtta
    53881 ctttaatatt ttcaacagtt gcatttttca ctgtttgagc taatgaagct aattgatttg
    53941 cccaaggcat attaatatta acgttaatta aattaatatt tttgatagaa cccccttcaa
    54001 ctctatcaaa taatggacga gcagtgttat gaatggagaa atgcttacca tcaacacttg
    54061 ttaagtgacc tgtaaattta cctgttacat atgatttact tggtgtaggt acatttgttg
    54121 catttaaatc cgatcctaat ttaaactcac cgttaggatt tttctgcata gcatctacta
    54181 aatctttgaa gttatagtaa acgttatttt gcgatgcttt gggtttctct atgtaataag
    54241 tgtatgtttg actcaaacta ttatttgaat cacgttggat taaatcagga gctgaagcag
    54301 taactttaaa taaggatgtc tcctcctcag ttacttcctc tatattagta atggcaagcc
    54361 ttgttacttt attatgatta gtggtaattt ttagataata tgacgttaga ttttctggaa
    54421 cagtttctag aaggctacta tctgtttcat ttccattctc atccactttc atcaatcttg
    54481 tttctttaat atctttaatc tcaacttttt taaggtctaa ctgaacttct ttatcttcta
    54541 atatttcagt ttcttcaccg ttacctcgat catagaccat ggttgtggat agtgtataac
    54601 cttgataata tttcaagttg tctaaagtag cttgtaagtt attttcttct accgttactt
    54661 ctttaacaac tgttccagta ttatctttta gagctacttt aatcgattta atttctactc
    54721 cagctggttt agtcaatgta taactagctg tcgcactctt cttcaagaca tctttatctg
    54781 ttttagccca ttccaaggtt ggtttctcta actcttttgt gccattctta ataattttgt
    54841 cttgaggttt ttcaatcact gtttctgtga tagtaggagc ggcacttgtt ttttctccgc
    54901 gaattgtttt ataggtttca gtaatttgtt tcttatcgtt tacaccttct tgagttactt
    54961 gtcttgttcc gcgttttaaa gtgtcatctt cttgttcttt tgtttcaaaa ggaatgattt
    55021 cttctcttgt ctcaaccgtt gtcccttcaa ttggttttgt accacggatt acctgttgat
    55081 ttacaggctc cttggtgact tccgtactgg ttgaaagaac ttggtcagtt tcaacccctc
    55141 ctattgtttt ataggttgtt tttgtaactt gacttccttt ttcaccattt cgtaggacag
    55201 tttcttcgtc cgtgtacttg gttgggtcct cagtcgtttc agttttatag tcaagttctg
    55261 tagttgattc ttcaacgagt gttccttcag tcaccttata ctcaggtaat tgttctggaa
    55321 caagagcctc acccacgtaa tcttcttctt gcgtcccctt agctgtttta gtctcctctt
    55381 ttggttctac agtttcttca gccttggtat ctggagttga ctcttcttgt ttcggtgtct
    55441 cttccgctcc cctatcttct ttaggatttt cttgttgtga tgtttctttt ggtgtacttg
    55501 gttgctcagc ttgtgtaggt tgcacgggtt gttctgggac ttttgcttgt tctactggtg
    55561 gttcaacttt tgattcctca gctggtttgt ctgatggttg actttctggc ttaactgcta
    55621 ctttttcctc tggttttgac tcaacttctc cacctacttc ttcaactgga gctggttctg
    55681 ctgaatcttc tttcccctct tctactttag gaagggtgtc gtcagtaggt tttacctccg
    55741 attttggttc ttcctttgga ctttcttctg ttttaggtgc ttcttctttt ggagcttcct
    55801 ctgtctctac tacttggttt tctgtcctag cttgctcctg atttgttatt gattgaggag
    55861 tctcaacttc gactacagtc acctctccag gttttgctga ggtttcttct aaaacagtgt
    55921 ccaagccaag cgttttgagg atgtcacctg atagataacc aacatagcga tagccctcca
    55981 tttcaacaac accctctcga ctagccagcg ctagggtcgc aactgggtct acagcccctg
    56041 cactaggaag aactaccaat cccatagctc caactagaaa gacgctagca attttctttc
    56101 tcttgtagat taaaagcaag ctcccaacag tcagcaaacc aaaagctgtc aaaacagatg
    56161 cttctgtccc tgtttgaggc aactgatctt tttgatacac caaaccatat acaacttcat
    56221 tcctgtcagg ctttcctgtc tgaattaaat ctttagcttc ttgtgaaata atctctttat
    56281 ttacatagtg ataggtggct gcgtccacta cagaaggagc catcaaaagg cttccaagaa
    56341 atacagagcc tacaactccc ttaatcttac gaattgaaaa acggtctttt ttaaacactt
    56401 ttatctcctt tattcattct caagactttc taatagcgtc ttgcggatag tgcgcacgcg
    56461 cacctccgat taattttgga cgactagcca gtgccgttac atgggcatga ccaatctctc
    56521 tcaaaatagg gcgaatcgga acctgaacat gcttgacatg catgccaatt gcagtgtctc
    56581 cgatatccaa tccagcatga gccttgataa attcaacctc aactggatcc tgcataaact
    56641 taaaggctgc caactgcccc gaacctcctg catgaagagt aggatggaca ctgacaattt
    56701 ccagaccaaa ctgctctgcc acctgacgtt caacaacgag agcccgattg acatgctcac
    56761 aaccttgaac tgctaaatgg atacctctac tacttagaat acccaagata gtctccacta
    56821 tcagctcacc aatctcttga ctggattctt tcccaatctg accacctagc acctcactag
    56881 aagatagacc taaaacaaaa agggccccct gcttcaaatt ggtcttttct aaaacatctt
    56941 ccactacctg acgtgtttct ctttgaatct gtgtctcgtt catctctgtt acctctgttg
    57001 tcactcttct atcataccgt tttttcttgt ttttagcaag atagacaacc tagaaagttt
    57061 gcccaattac gcataaaact cccagaattg actgggagtt agctagtttc tattctattt
    57121 atatatattt caactttcgt ccctttttgg ggtctagaat caatcttcat ctggtaattg
    57181 gctccaaaat gaagtttgag ccgttgatcg acattttgaa gaccaactcc cccacgtttg
    57241 agttgacttt gactactatc accagcatct tggaagccaa cgccatcatc ctcaatacgg
    57301 atgaccaatc ccgaatcctg tttctggaca gaaagtttaa tatggccctg accttccttt
    57361 tccttaatgc catggtaaag agcattttct acaaggggtt gtaggaccag cttgggtaag
    57421 actaaattat caaaggtaac attttcatta atttcgtatt ccagcttatc tccatagcgt
    57481 tgtttctgga taaagagata ctggcggaca tgattgattt cgtcagagag acaaatcaag
    57541 tccttgcctt gattgagcgc caagcggaaa taggttgcca aggacttggt cacctgcacc
    57601 actcgctgac tatcatgaaa ttcagccatc cagatgatgg tgtccaaagt gttatagagg
    57661 aaatgtggat taatctggct cgaaagggct tgaagttggt actgacgggt cgtttcttcc
    57721 tggctacgaa tagctaccat caactgatca atctgatcca acatggcatt aaattggcga
    57781 gttacttctc tcagttcata ggcaccaact tccttggcac gaagattttg agcaccagaa
    57841 gcaatttcca acatggtttc tctcaaatcc ttcaaaggag caatccagcg tttaagactg
    57901 aaccacacta agcagagaca gacaagaaga gatgtgacac tggccccaag caaggtccac
    57961 aagagctgac tccgaacctg gtctaacttt tccaatgatg acacgccaag taccgtccaa
    58021 tcagttcctg caatcttctc ttgactgacg taggatttgt gaccaggagt ataaccctga
    58081 cctgtatcga tgtagggttt catagcctcc attttgctag acgaactata aactgtgtgt
    58141 tgaggatggt agacaaattc atggttttca ttgataatga aggcaaagcc ctgctgcccc
    58201 aactggagtt gattgagata ggcttccaga gtttcataag aaatatccaa acgaagcaca
    58261 ccaagattgg ctccctttgc atcaacaagt tcttgagtga cagaaatgac ccactgacta
    58321 tctgatttac gagctggagt caaaacaggc atagctccct gatgaatggc cttttggtac
    58381 caatcctcag ccatcatatc agaggaagtt ttcatctgca cactgtcatc tgtagaaatg
    58441 acctgaccag atttggtcac cagcacaaca gttttcaagt ccttatctga cttcaagatg
    58501 gtcaaaaaca aatctcggat tccctcgacc ttgtcttgac tgggattctc agcataggcc
    58561 agaacatccg tctgctgggt caaaccggtc gaagtggttt ctagtttttt gatataagac
    58621 tgaataaagt ggctagtctg gctgatggtc gtttggctgt tgccctcaat ggtggcctca
    58681 atggctgaag aacttgattg atagtagaaa gttccaacca gagctaggag aatgagaaag
    58741 accagaaaga tggaaataac cattctaact aaaagagaag aacgcttcat cggtcttctc
    58801 ccttcttaaa ctgacgaggt gtcacacctg caatctgctt aaaacgttgg gtaaaatagt
    58861 tcatatcttc aaaaccaacc ttctctgcga tctcataaat cttcagatct gtagttaaaa
    58921 gcaagagctt ggcttgttta acacgttctc tcaccagata atcctgaaaa ggcaagccca
    58981 actctttctt aatcaaggaa ctcagatagg tcggactaaa acctaagtca ctggctaaag
    59041 actttaaact aaattggcta tcagccagat gagactggat tttctgggcc atgtttcctt
    59101 caaacctatt agtcaataaa tcttgtaact gctcttcttt ctcttccttg tctagttttt
    59161 gtttgatttt ccccaacatt tcctcaatat cctgacgaga aaagggtttg agcaggtagt
    59221 cgtccacacc tagtttgaca gcagacaagg cataatcaaa atcatcgtaa cctgttaaaa
    59281 agaccaaatg aacctgagga taggtttctc gtaccagact ggccaactgg atgccattta
    59341 gatgaggcat gttgatatcg gttaaaatga tatctggcac ctgcttttgg atcaattccc
    59401 aagcctgcct tccattttca gcctgaccga tgatttccat atcgtaggct gctacattga
    59461 ccagtttagt caaaccttgt cttaccagat attcatcttc tacgattaag attgtgtagg
    59521 tcatgatctg ctcctttacc acttactagt atcagtatag caaaattctc ctctaactgc
    59581 ttaggaaaga cctcttatac tcaataaaaa tcaaaaagta aactaggaag atagccacag
    59641 gtttctcaaa gtaccgcttt gaggttgtag ataaaactga cgaagtcagc tcaaagtata
    59701 gctttgaggt tgtagataaa actgacgaag tcagtaaccc tacatacggt aaggcgacgc
    59761 tgacgtggtt tgaagagatt ttcgaagagt attaatcaac ataatctagt aaataagcgt
    59821 agcctttttc ttccatttgg tctttgggaa taaagcggat agagaggcta ttgatacagt
    59881 aacgtaagcc gcccttgtcc tgtggaccat ccgtaaagac atgcccaagg tgagaatctc
    59941 ctactcggct ccgcacttcc atacgcgtca tattgtagga cttatcttcc ttgtaggtga
    60001 caacatctgg actgatgggt tgggtaaaac taggccagcc acaaccagac tcaaatttgt
    60061 cttttgatga aaagagaggt tccccagttg ctatatccac atagataccg gattcaaatt
    60121 tatcccagta acggtttgag aaagctcgtt ctgtttgatt ttcctgggta actgcatact
    60181 cctcaggtga cagggtcttt ttcaattcct catcacttgg ttttggatat ttgctggcat
    60241 caatgacagg ataggccgcc tgattaacat tgatatggca gtagccattt ggatttttct
    60301 tgagatagtc ttgatggtaa tcctcagcca ccacaaaatt cttcaagttt tccttttcaa
    60361 ctgctagagg ttgatcgtat ttcttagcca cctcatcaaa gacttggtta atcacttcca
    60421 aatccttgtc atctgtgtaa taaacaccag tacggtactg ggtccccaca tcatttcctt
    60481 gtttattttt gctggttgga ttgataatgc ggaaatagtg aagcaggatt tccttgagag
    60541 aaatttgctt ggcatcatag gtgacatgga cggtttctgc atgacctgtt tggttaatca
    60601 attcgtactt ggttgtttct cctctaccat ttgcatagcc tgaaacggca tccgtcaccc
    60661 cgggaacgcg tgagaaatat tcctccactc cccagaaaca acctccagct agataaattt
    60721 cgtgcaagtc tgcgtcttta ctaatttctg tttttttcac tgcttttcct ccttggctaa
    60781 ctgccgcctt ttcaatttgc gaggcatctg tctgccctgc atttcgtatc aatagaacat
    60841 agaaaccggt tatggctaga aaaaatactc ctagcaacaa gaagattttt aacttatcat
    60901 tcataagaca cctcctaggc taattccttc aaagtttgca aaattgcatc tttttccatg
    60961 aatcctggat gtgttttgac cagcttgcct tctttgtcta taaaggcttg ggttgggtaa
    61021 gaacggacac cataagtttc caaaagtttg cctgatgggt caactaggac tgggagattt
    61081 ttataatcca atcccttata ccaattctta aagtccgctt cagattgctc tcccttatgt
    61141 cctggtgaca ctactgtcaa gaccacatag tcatcaccag cttctttagc aatttcatcc
    61201 gtatctggaa gactagccag acagatagaa caccaagaag cccagaattt gagatagact
    61261 ttcttgccct tgtaatcaga taaacggtag gtcttgccat ctactcccat caattcaaaa
    61321 tcagccacct ctttcccttt agctgcgctt gttttactag ctgtctgctc cgtcttcatt
    61381 tcatctttcg tttggtgttc actagtcacg gacttgcctg aacaagccgt caaccaaagg
    61441 agcgaacctg ctccaagaac acatgtttgc cattttttca tattgatatt cctttccatt
    61501 ttattcaaat aattgactta aaattgaagc atttccaaac agaaccaaga gtcccatcac
    61561 aataatgaga aaaccaccca cttttttgag gattccgaga tagggatgaa gttttcggaa
    61621 atgtttcaaa acataactag aggtcagagc tagaagcaag aatggtagcg ccaagcccag
    61681 cgtatacacc aacatgagac cagctccctg ccaagctcct gaaccacctg aagccgccaa
    61741 ggccaaaaca gaccccagaa ccggccccac gcaaggcgtc caagcaaaac taaaggtcaa
    61801 gcccaataaa aatgcctgac tatagccctt accattttgc ccctgtcctt gcagttgtag
    61861 cctcttttcc ttataaagcc ccttaaagtg tagaatctcc atttggtgca aaccaagaag
    61921 gataataatt gccccagtaa gatattggaa ccaagaagca taaagcaaat cgcctaaaaa
    61981 accagctcca tagcccaaca aaataaatat aaaggaaatt cctgctataa aggccagagt
    62041 tcgtaataaa ctagtaactg agattgaaaa tttgccgcta gaagcctgag caccatcctt
    62101 atcatctagt aacactcctg tatagaccgg taacaaaggt aagatacaag gagaaaagaa
    62161 ggatagaatc cctgccaaaa agacacttag aaaaaagaaa atatgaccca taaagttcct
    62221 cctatcattt tattgataga tttattatac tccttccatt ttcgaaaaaa cagggacaat
    62281 gataggggaa aataggaatt taatcagatg atttagaaat cttggacaaa aactatacaa
    62341 aaaactgtca aagcacaaaa gcgcatagta tcaagattct ataaagcctt gatactatgc
    62401 gcttttgtaa tggataaata gttagtcttt tttaaagacc ggatctttca aactctgcat
    62461 actggcattg atcaccgcgc ctaggataac aattttagca atcaagataa accaaaacat
    62521 cataacaaca agaagaacgg aacctaaaat tcggacatcc accaaatgat ggacatagta
    62581 attgagataa ctagagaaca gagttagtaa acctaaaatc actaagagaa caaaggcact
    62641 gcctggtagg gtatagctaa ttttcctgtt agatagattg ggaagaaaat aataaagcat
    62701 gaccaagata gcaaagagga gggcgtaaat cagaggacct gccaaccctt gtaaagcctg
    62761 atagataatg ccatcttttg tccaataatg agcaagtaaa gccaaaatca tctgaccaaa
    62821 taagatcaaa aacaaggcaa acgcaaagag gagctgcaag ccaaaactga ctaggagact
    62881 tagcatctga tgggaaataa gtccacgact cttttcgacg ccataagcct tgttaaaagc
    62941 tttttgcaag aaattcatag attttgaaaa actccataac gccgataaaa cagaaaaact
    63001 caataaacct gttgaaggtt gcgtcaagac ttctctggct attttttcca caccttcata
    63061 gaggcttggg ggcaggacgt ctttcataaa gcccagaaat tctcccacag gaatctgaaa
    63121 ataggggagg atattgacca ccaccaaaag cagggggaaa atcgaaatca accaatagta
    63181 ggctactgcg acactggtca actcactatc tgatgcttga taataatgca aaaaagcttt
    63241 taataaaggc ttgtctatca gctctttcca ccactttttc atgtcatact ccttcattta
    63301 taatcttata ctcaatgaaa atcaaagagc aaactagaaa gctagccgca ggctgctcaa
    63361 aacactgttt tgaggttgta gataagactg acgaagtcag tcacatatat acggtaaggc
    63421 gacgctgaca tggtttgaag agattttcga agagtattaa ctaatttctt cttaccaatt
    63481 ccaccatatc atacggcagg gtattggcag cttccttcaa ggaatagttc tctaagttat
    63541 ttacattttg tcgtaatttc ttggcatact tagttgtaat taatcgtttt tcttcgtatt
    63601 cgaaaatcaa cttgcgctcc agataatagc ctctcagcat ttcattgata ttgttgggtt
    63661 tgacacgatt gataacccgt tcgacaaagg caccactgct gataatagtt gtttctcgaa
    63721 gacgagactc ctgcataaaa ctaatcaaag agcgtctgta gactcccttc aggttttcca
    63781 aactttcaat aatcatctcc gtattggcaa gatagagctc tgcaatttgg tcataatcaa
    63841 gagcacggag acggctttgc tccttgttct tccagctacg gaaggtcttt ccgagagtaa
    63901 aaacttcatg aaggagaaaa cgtaaaatcc gcaaagaaac aaggaaataa taggtcagtc
    63961 ttgaggcaag tttacgattg attccttgtt ctatattttt cagataacgt tggtaaactc
    64021 ggtaagcacg attgctaatg ttcccctctt cataggcctg ttccaaacca tcactttcaa
    64081 tactaagaat caagagtttc aaagcagccc aatcttcttg atcatcctgg ttttcttggc
    64141 ttaaaatgag attttcaata cgtccatgat aattgtcaat agccgcatag aggggaagtt
    64201 tatttctggt gtcttccaac tctttttcca actctagcgt tacttcattc aaaatggcga
    64261 tatgcatgag ataatccttg ctttcttcct cttcatcaga aagatgaggc aagaccaaga
    64321 gacctgttaa aaagctgaca agcgtcacac ctgcaacaag gaaaagcaag agaggatact
    64381 cctgttctag attacttggt atcaagagaa tcgtagcaat cgacaccgtt cccttaacac
    64441 ctgaaaaggt caagagaaac atgtccttca tatacttatt tagctttttc ttgaggcgtc
    64501 gggttctata ggcataatag ccatagatca taataaaacg aatgacaaag aggacaaagg
    64561 taaggacgat gagagatagc aataaaagta gaggattata gattggattg gtcaagatag
    64621 gttctgctat catttccaac tccatcccta aaatcacaaa gacagaaccg ttgagcataa
    64681 aggtcactgt atgccagacc gtctcggtca ccgtatccac ttgggcttcg aggagcgtga
    64741 ttttcttgaa gcgacttgcc tttaaaattc cagcaactac gacggcaata atccctgaaa
    64801 catggacttc ttctgccaga aagaaggtca ctagaggcaa actcaattct aataaaagtt
    64861 cactggcaat atccgttgcg cgcacactta gcaagaaggt atggaggaag cggttggtca
    64921 tggctgttaa aaatccaatt aaaaaaccgc ctaggattga aaagatgagc gaactgctag
    64981 cttgccccag agaaaaagct ccagttgtcc aagctgtcaa agctacctga aaagccacca
    65041 aaccagaagc atcattcaag agtccttcgc ccttaagaat attggacacg cgcttaggaa
    65101 agctaaaacg ctccgaaaga gaggcaaagg ccaccaagtc cgtaggacca agggctgccc
    65161 caacagccaa gcaagctgcc aagggaaggc tgaaccaaag aagatgggcc aagccaccca
    65221 aactcagggt cgagataaaa atcactggaa atatgagata aacaatgatt cgccagtgtt
    65281 ttaaaatagc cgtaacatct gcttcttcag cctctcggaa aagcaagggt ccgataacca
    65341 gtgccaaaaa caactccgta ttaaggtgaa agtcagtatt gggtaaaaag agaccaatca
    65401 caattcccaa aagaatctgc accaaaggga gaggcaaaaa gggcaggagc ttattggttg
    65461 tacttgagac aatcaaaacc agtaaaaata ggatgaggta aatcagtaat tccacgcacg
    65521 tcctccttaa tcttttttac aacaggattc aaatatctcc ttctgctctt tgattttttg
    65581 gtcaatcttg gaacagtctt tgtgctcaat ttttctctgg caccgttcca tttcaagagc
    65641 aactaatttt ttcttgattt taagcatttt tttgctcata tgtacttggt ctagcacgcc
    65701 caccgatcgt tcgtggtggg ttgattcaac aaaattctgg cgcatggcat ccagcttttc
    65761 gtgtaggtat tgtttatcca tgtctgtatc tctctaattt ttcaatcatc actaaaaacg
    65821 gcgggttgtt gacttggttt aaagttcggt aaatggcagc tgtgtactct tgttagttca
    65881 actggattac aaaatccaag acagcatctc tctcgaggtc gcctccttca tgaccatagt
    65941 aaatcataat agcaattcgt ccacctttga caagtaagcc acatagcttt cctaatgcct
    66001 caatcgttgt ctgcggtcgg gtgatgatag acttatcagc tgacggcaaa tagcccagat
    66061 taaaaatccc tgccttagct tttgtcacaa actggtccag tgtctcatgg ccttgcaaga
    66121 ttaactgggc atttgtcaag ccagcctgat gcaaacgctc ttgggtcttt tccaaggctt
    66181 gcttctgaat atcaaaggca tagacttgct tggctagctt ggctaaaaaa agcgtgtcat
    66241 gaccatttcc catagtcgca tccactacga catcctcttt tgtcacgacc tcagccaaaa
    66301 aatcatgtgc catctcaagt ggtcttttca ttttcaaact cctgttttac agccttgcat
    66361 ccttgaacac ttccacgacg tcgcatctcc atctcaatgc tgttgagagc ttcccattta
    66421 ttgaggctcc acataagccc aatcagcata tccctaggtg catctcctgt gattcgatgg
    66481 atgacgatat gtttgggaat aatttccagt tggtcacaga tgaccctgac atattcgtcc
    66541 tgactcatca attgtaaacg tccctcatgg taatctcgtt gcatacgagt atttgtcata
    66601 agatggagca aatgcagttt aatcccttga atatcgttat ccgtgacaca acggcggaca
    66661 ttttcaacca tcatctcatg ggtttcacca ggcaaaccat tgatcaaatg ggaaacaatc
    66721 tcaatttttg gatactttct caaacgcttg accgtttcca cctacaattc ataagaatgc
    66781 gcacggttaa tcaggtcaga ggttgcttca taagtagttt gcaagcccaa ttcaaccgtc
    66841 acatgcatgc actccgataa ctcagccaaa tattcgatgg tttcgtctgg taaacagtct
    66901 gggcgcgttc caatattgat tcctaccaca cctggctcat tgatagcctg ttcataacgc
    66961 tctcgaataa cttccacctt ttcatgggtg ttggtaaaat tttgaaaata aaccagatac
    67021 ttctgaacat ccggccactt acggtgcata aagtcaattt ccttataaaa ttgctcacgg
    67081 ataggcgcat ctggggctac aatagcatct ccagaacctg aaaccgtaca aaaagtacag
    67141 cctccatgag ccacagttcc atcacgattg ggacagtcaa atcccgcatc aatagggact
    67201 ttaaaagtct tttctccaaa gagttttcga taataatcat tcaaggtatt ataaggtatt
    67261 ataagatttt ataactttca ttataacaaa aatcacccac aatctcaaaa gcctgacttt
    67321 cctataaatt cctctgtttc tcgtttccat tagccttttt ttatgataca atatgggtat
    67381 gattttaatg aaattagcat ctattttatt attgatactg accttagtca tctgcattat
    67441 cctaaccaaa ctttttagat taaaaaaact aggacgaaac tttgcggatt tggcttttcc
    67501 agtcttggta tttgagtatt acttgattac agctaaaacc tttacccata atttcctccc
    67561 tagactgggg ctagccctct cgatcctagc cattattctc gtctttttct tccttttgaa
    67621 aaaacgcagc ttttactatc ctaaattcat caaattcttc tggcgtgcag gattcttatt
    67681 aacccttatc atgtatatag aaatgattgt tgaattgttc ttaatgaaat agtcgaatcc
    67741 ctaagcattt tctagggatt tttgctttct ctacaaaata gtatagacaa taacactata
    67801 caattttata caaagaaaag agtctgggac aatagtctct tatatccaaa aaggcaacgg
    67861 atttgccgtt gcttttttgc atggttacga tagtcttggt aaaatagaat tgcttaataa
    67921 accatttaga aaggctatcc catgcatatt cactataaca caaatcaaac aactttacca
    67981 ctagaaatca gttccttctt accacaagac catctcgtct ttactattga aaaagtggtg
    68041 aataccttgg aggaacgtca cttctacgcc ttctatcatg cctttggtcg cccgtcttat
    68101 caccctaaaa tgcttgtatc tactcttcta tttgcctatt cacaagggat tttctctggt
    68161 cgaaaaattg aaaaatggaa gagttagtga ccttagattg tttgtttatt gacggaacta
    68221 agattgaagc caatgccaac aagtatagtt ttgtgtggaa gaaaacgaca gagaaattct
    68281 ccgccaaact tcaagaacaa atacaagtct attttcaaga agaaatcact cccctcctga
    68341 ttaaatatgc catgtttgat aaggaacaaa agagagggta taaacagtca gctaaaaact
    68401 tagcgaattg gcactataat gacaaggagg atagctacac acatcctgat ggctggtatt
    68461 atcgttttca ccataccaaa catcagaaaa cacagacaga ctttcaacag gaaatcaagg
    68521 tttactacgc tgatgaacct gaatcagccc ctcaaaaggg actgtatatg aacgaacgct
    68581 atcaaaactt gaaagctaaa gaatgtcagg cgcttttatc tccccaagat agacagattt
    68641 tcgctcaacg caagattgat gtggaacctg tctttgggca gataaaggct tgtttgggtt
    68701 acaagagatg taatctgaga ggcaagcgtc aagtgagaat tgacatggga ttggtactta
    68761 tggccaataa cctcctaaaa catagtgaaa tgaaataaga acaggacaaa tcgataagga
    68821 cagtcaaatc gatttctaac aatgttttag aagtagaagt gtactactct agtttcaatc
    68881 tactatacaa taagagaacg actcaaaatt aaaaagctag agttccgcaa ttggaaatat
    68941 ctagcttttt tgtggttgag aactattttg ttccagactc tttatcttct atttaggaca
    69001 agagtttttc tttggtcttt aatgataaag aaggtatcaa aatttctagt cttctttttt
    69061 acctttagta actactaatc ctgcactcaa acctagaaga gctaaacctg ctgctactgc
    69121 tgcttggctt gccgcactac ctgtatttgg taactgggct ttattagttt gactagcttc
    69181 acttgaatca attggttttg tatctgcttt ttctgacact tgtggttttt tagcttcttg
    69241 agctactggt ttggttccaa ccaagacgat gcggtctgtc ggagcttcta ccacttcacg
    69301 gagtttttct tccttacttc catcaggatt aatcgctgta aagatacgtt ctttaccagt
    69361 ttttccttct tgttctacac gagtttcacc tagatacagt gttgaatctt ttttctcaac
    69421 tgtcttgtag gccaaatctt tttcaacaaa ttcgagtttt ggaagatctt cttgtacagc
    69481 agaaactggt ttttccttag tcaactggat acggtattcc ttgacttgtt ttccactttc
    69541 tgaaacgagg cgaacaagta ctggaaggct atcttctcca ctatctacca cagttgaagc
    69601 tacttgattg ttttcttcaa ctgagacttt tggccgttga cctttatagg taatttgata
    69661 gtcttgacga ttttcagcga aatcagcaag ttcttttcca tctacaagaa tcttcgattg
    69721 cgtactttct tgaggcaatt cacttggtgc aaggaaggtc atctcaatca tcgcaacacc
    69781 gctcttatct gctttacgct ccatacgcca tctcatagct ttggctttga cagctttaaa
    69841 tgttacgttg atttcatcac cagctgcgat gtctttatcc gcacgataag gcacagcttc
    69901 ccaattttct ggattgttga atggatggtc tgcgtcgtag gcttggtagt ttgaatagta
    69961 ggttggcact tcaaactctg gaccgacata gcgttctaaa acgagtttag ttggtgcatc
    70021 cgtaccacta tctgcaaaga agtgaagttt ggcttgagca acagtccgtt ctacaatctt
    70081 accattttca cggaagatca cacccgctga tacttctgga ttagaagatg gtgttggtga
    70141 ccagtttgtc caacgacgat tttctgaatg atctccgtca ttgagatagt caacgcggtc
    70201 atgagagttt ttgtcaatat catttgttgc tgaagcaaag gcctggttac tgttttcatc
    70261 atagttaggg ttatctgaaa gagcctcacc aagtttgtct gtcactcgta cagtgacctc
    70321 agcaacaagg tcactaccaa ggacacggcc tcgaatagta aattgacctg cttttgtcag
    70381 attttccgct ggaacttctt cccattcaac tgtcaggtct tttgtttcgt agccgtcttt
    70441 acctgtgaag taaactggaa ccttagtcgg caattcaagt gcttgaccta cttgtagcaa
    70501 gcgagcttgt ttaaccgcag caactggttt atgagaaagt aagttcttat ccttagtgaa
    70561 gtgcagacgg tattctccta agatgtcgcc attttcagct ttcgcgatga cacgaactgg
    70621 ctcaccttca cgaacgcttg gaacgacggt agcgagacca ttgttgctaa cacttgctgt
    70681 gaccgccgta acttttccat ctacagactc aaggtagtag tctgtcaaat cagggttgaa
    70741 gtttgctaag tctttgccgt caacttggat tcttgtttgt ccttgtttgg ctgccgcaac
    70801 ttgtttcgca aagatttgta cctctgtgat agacgttcca cgcttgttat ctgctttaac
    70861 catgcgaata cgaacagcat aggtttcaac tttatcaaag ctaaagtggt tcatttctcc
    70921 agccttgagt tgagcagggg cttttagatt agtaactggt ttccagttgg cagaatcatt
    70981 aaagacatgg tcctcattac caacaaaact agggttttta ggagctgttg ggacagtctt
    71041 accaacataa tactcaatca cataagactt cggtgcacca actccatggt cttcgtggaa
    71101 tccgacactt agattatcaa cggagcgttt gctcaagata cctgaatctc caaacagaac
    71161 accgactgaa gcttctggat tactacgatt ccagtttgtc caacgattgg ctggttggtt
    71221 attgtaggaa atgagcttgt cattaacatt tgaaactggg tcgcttggat ttgagtctga
    71281 agcaaaggca agtggcaatt ctgaaccggt ccattggtca gaaatgtttg caccttgctc
    71341 agtttgagca gatacgcgaa catgaagttt agttgttaat tgagtacctt ctaagcgacc
    71401 attaactgta aagacacctt ccttagcgta ttgctctgga cgaatcgcat cccatgcaac
    71461 cttagctgat gaaacgtgac catttgaatc atatgtccga acactttctg gtaattgtgg
    71521 tgcttctgcg attggagttg tcacactgac ttcttcaact gaaacgatac cttctacaga
    71581 gacttttgca cgcgcttcaa ggtcaattcc ttcaacttta cctagtactt caaatgtttg
    71641 ataggagtct agtttttctt tcggaatagc ttgccaagtg actttatgag ttttagggaa
    71701 acctttgtca tactcaactg ttactgttgc tggaagactt ggttcctgat gcaaatctgt
    71761 cactacattt acaggacgga tggattgcgc aatcttcttc tcagtattgg cttggatagt
    71821 gagttcaact tggcctttag ctccctcata ttcagcgttc agagtgactg ctcctggctt
    71881 atgcaactca agcattcctt tacgaattgc gacttcccct tcaccacttg tagagaaggt
    71941 tactttatca gctggtaata cagcttgcgt tccatcttga tagtgagctc gaaccgacaa
    72001 tttgacagtt tggtcttctt tgagactgtc agctttttcc acttgcaagc tcaagtgagc
    72061 aatttttggc gcttcttcaa ggaattgaat tgcataggtt tgaagagggc caccatcttt
    72121 aggctgaata aagatgctcg cacgcatgcc gtttgctgcg cttgcttgaa gaactgtcac
    72181 atcagcattt tcagcacttg ctgtgacttc tggcaattgg gcaccataag atagagtacg
    72241 atattgcatt ggttgtcgac tagtaagacc tgttactgct tcacctccaa cagtaacagt
    72301 tggcactaca ggtgctgcag gattgccttc ttctaccaca agggttgcat gaattggttg
    72361 accttctaaa taaccggtcg cttgaatacg agaacctgga attgctaact taactttatc
    72421 ttcttcggca atctcccagc tatctacttc gtactcttgt acacttccat cagtcaaaac
    72481 ataggaaaca gatttgtcta cagaattcaa gtcagtattt ggagcaatac gtttcacaac
    72541 tggtagctct gatttaagag caatcacttc tacacgagct tctacttctc gtccgtcagc
    72601 catacctttc accgttacaa taccaggctt gctcacatct actgaagacc aggttacagg
    72661 acgttctgca cggctaccat cactgtatac aaacggaaca gtggtaggca tttcaggtgc
    72721 ctctccaata atggtctgta cttttggcac ttctgtcccc aaaacagtct tctcttgtcc
    72781 ttctttttta ccagtaaaga cagtgacttg gttcgatttc aagagatcag agtgggcagt
    72841 aagggtgaat ttccctactt gttcagttga tttgacaatg gcaacacctt taccattaaa
    72901 tgctttacga atccaagaac catctgcttg cgccttatag cgttcacggc tggcttgttc
    72961 tccgttatct acaccgacca gttgaccttg gccatgcaat tggaagcgaa ccagattatt
    73021 agcagttgga accacattcc cctggctgtc aacaatttca tagtagatgt aagtcaagtc
    73081 ttttccatct gctgcaatcg catggtcttc cttaataaga cgaactgccg ctggcttacc
    73141 agcagtcgta atcttatctc gagcaatttc cttgccagat tcatcacgag caattgcttc
    73201 caaggtacct ggttgatagg caactttcca ttcaagataa agttcattag catttgcacc
    73261 ttcttggtaa gtccgcccat cgctggtttg ttttttattg aaagtcttaa gaccaagaga
    73321 ttttccattc aagaacaatt ctacactaga agcattcgaa taagcacgaa ctggaatctt
    73381 accttctgag tcagctactt tggatgctaa ttctttgttt tcccagttcc agtgaggaag
    73441 aaggtgtacc atcggtttct tcttaacaga aacccattgg ctttggtaga gatagaagtc
    73501 atgttttgga atgccggctg tatctacgat accaaagtaa gagctcttaa caggagtttg
    73561 attttggttg tgccatggtg taggttcacc aatatagtcc gtacctgtcc agataaactg
    73621 tccagcatag ccagcgttgt cacggtcaaa agtccatgaa gcggttgctg ttttccccca
    73681 acccacacga tcattcccat agtcagactg ttcataatta cgctcaggtc cattgctatg
    73741 tttcaattca cgttcagggc gatagtaact tccacgtgta cgggttgctg atgatgtttc
    73801 tgaaccgtaa atcaaccatt ttggatgctt agctctaagg gctttgtaat tatcttcaga
    73861 atagttaaat ccaacagcat cgagttcatc agcaattttc tcatgccctc cgctaccatt
    73921 accgaaacgg aatttatctg ctcccatggt aacatagcga gtcttatcaa catccttgat
    73981 aaccttgacc aaacgtttaa cagttgctaa agagtgggca tcaccattag cttcacctat
    74041 ttcattacca attgaccaca tgaagatagc agggttgttt ttgcctcttt cgaccatggt
    74101 acgtaggtca aaatcagacc atttttcacc ttttcgagct tctgggtgag tggcatcttt
    74161 ttcaaagaaa cgtccatagt cataaggttt cttgccacca taccacgtat caaaggcctc
    74221 ttcctgaaca agtaaaccta gttctgctgc gatttgcaag gtttgctcac tagaagggtt
    74281 gtgggttgta cggatggagt taactcccat ctccttcatt tgtttgagac ggcgatattc
    74341 tgctttatag ttttcttctg ctccaagcgc cccatggtcg tggtgcaagg atactccatg
    74401 gaatttaata cgttcaccat tcaaagagaa accttcattt ggagtccagt gatagtaacg
    74461 gtaaccaaac aaatccttct tagcatcaac caattgaccg tcacggtaaa cacgcgtaat
    74521 caattcgtac aaggcaggtt tgtcatttaa aacggtccag agttttggtc tttcaacttc
    74581 taaaatcgca tctaggcttg ttgattcatg tgcttttaag gtacgactcg ctgtacgaac
    74641 taagcctgtt acagcatgac cacctcgttc aacgatttga tattcggcta caagttcatg
    74701 gtctttgtcg tccgtattga cgattttgct ggtcacatga gtttcaacct tgccatgttg
    74761 ttgttcttca agttttggtg ttaaaatagt tgtcccattt ttctcaacat gcaccttatc
    74821 tgtcacttgt aaagtcacat cacgatagat accacttcct gaataccaac ggctacttgg
    74881 ctgtttgttg actgcatgga cagcaatcac attctcacga ccatctttgt gaaggtattt
    74941 ggtgatatcg tatgagaact ggttataacc atttggataa tgccccacta actgaccatt
    75001 gacataaact tgagaatcca tgtagacgcc atcaaaagta aggcgaacat ttttcttgag
    75061 gtctttttca tctagtttga aaatcttgcg ataccaagct tccccaccgt tgagctgtcc
    75121 accttcattt tgtgcaggag attcatgatc gaaatcgtta aagatactcc agtcatacgg
    75181 taaatctaat tttttccacg tagatacgtc tgcatcaggt ttaatggctt ccttagaatt
    75241 tgcattgagt ttaaaatacc aattttgatt aaaatccact ttcctgtctt caatcatttg
    75301 attcacttct tcatttgtta cagctttagc atcttccttg agcggttttt cttgatttga
    75361 agcttgtgat tctatccttg gagctttttc ttccggttta gcagacactt tttcctcttt
    75421 tggagttacg gcttcatctt ctttcttctc agatgcaata gcctcagttg aactaggttc
    75481 actttgttct gtcctttcaa ctacattttt agtttccaaa gctttatcag ccttttcttc
    75541 tactatcatt ttttcctctt taggtttctc agcagtatga gtaataagtg tttcatccgc
    75601 ataaactaca gattctccag ctatatttcc tcctaataga actgcacaag tcccaatcat
    75661 tactgagcaa gctcccacag caaacttacg aatgctataa actcttttcc gattccaatg
    75721 gcctttcccc ataaaaccct ccttatatta tatttagtgc agttagctac taccaaagcc
    75781 caagtggtat acatggtatg acaacctagt ttcaacaatt tacactctgc gaaaatccaa
    75841 ttcaaacttc gtcagtgtcg ccttgccgta gatatgatta ctgacttcgt cagtttcatc
    75901 tacaacctca aaactgtgtt ttgagcaacc tgcggctagc ttcctagttt gctctttgat
    75961 tttcattgag tttatatttt ataggagcgc attattttgc ttttgctgcg tactcttcgt
    76021 tacgtttgat catttgtttt ctgtaccaag caaagatacc gatatagaat acaaggaagg
    76081 ctactgcacc aaggattgct ttgatatcac cagttgtagt gttaccaatt gtccaaccaa
    76141 gaagtttttc gattggtcct tcaagagtag agtgagtaat caattgagtt tggctcacac
    76201 cttctgggaa ggcacctaca cctttagcaa gttctgttgc aaatggtgca ataagggtac
    76261 ctgaaagaag gaagagtggc aacaagagtg ttccgaagat aatcatacgg agcaatttac
    76321 cacgagttac aaccaagaga gctggagtaa cacccatagc gatgatacct gcaagtggca
    76381 agataccatt tccaactttt gaaagaagca ctgcttcaat caacatgatt ggtgcaagta
    76441 cgttggcaca agcccagatt tcagcacgac cagcgatgaa tggccagtca agaccgatat
    76501 tgaatttacg tccttgaaga cgtttagtag caacgtttgt aataccttgt gatagtggtt
    76561 ctacggctgc gatgaaccat gaaccgataa gtgagaagag ttccaaagat acaccggcag
    76621 tcaaaccaag agacaaccat cctttgataa caagacgcca tttatctgca tctgcaacac
    76681 ctgcaattgg atgtggagtt cccataatac cgataacgat accaaggatg aaaccgatga
    76741 agaatttaga tccccagaaa ccgattttct tgttcaattt agcagcatca aagtcatatt
    76801 tatcaaggcc tgggaagaat ttttcaaaaa tcttatccaa aaccatgata actgggttca
    76861 tcatgtagtt catgtgagtt gatgtcattg gtgatgaact tggggcgtta agaaggtcat
    76921 caaatgtagg tttcatcaag tcagagttga taattttcaa cacaccgaca aggacgatag
    76981 ctgctgtagc aataaagagt gaaacccctt gactcacacc attgttatca gcataccatt
    77041 taatcaagag acctgtgata gacaagtgcc agatatcaaa gatatcgaca tcaagtgtat
    77101 cggttttctt catagcaagc atcactacgt tgacaatcaa catgatgagc aagaagtata
    77161 gtgtccaagc agaaccccaa gtgattgttg cgagtggtgc ccaaccaacg tctgtaatac
    77221 tcaattggat accagtgttt tcaacgaatt ttgcaagtga tgctgagaaa gcaccattta
    77281 gcataccgat gatagcaccg atacctgtaa gagcgatggc aagtttgata ccaccttcaa
    77341 gcgctttgga gaatttcact ccaaaaagta aagccaatac tgtcaaaatg attaacatga
    77401 tgacaggtcc acccatttct aagatgggat tgaaaacctt tccgattagg tcaaagattg
    77461 catccataac agttcctccc ttttttatgt tatatgaatg ttaacaaatt agaattagct
    77521 taatccgtgt tctttaatag ctgcttcaat attgtcaaat actggagcgc tcattgctgg
    77581 gatacggaat aagattgg
//
LOCUS       DAVHSI010000005        76141 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.005, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000005 DAVHSI010000000
VERSION     DAVHSI010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 76141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.005"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..996
                     /locus_tag="VVR21_000325"
     CDS             <1..996
                     /locus_tag="VVR21_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU6054272.1"
                     /translation="NITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVSK
                     ILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVG
                     DETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDS
                     FAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIE
                     AIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIKI
                     LVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            1391..2254
                     /locus_tag="VVR21_000326"
     CDS             1391..2254
                     /locus_tag="VVR21_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6054273.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEGV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            2540..2773
                     /locus_tag="VVR21_000327"
     CDS             2540..2773
                     /locus_tag="VVR21_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054274.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            2795..3472
                     /locus_tag="VVR21_000328"
     CDS             2795..3472
                     /locus_tag="VVR21_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6054275.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            3484..4149
                     /locus_tag="VVR21_000329"
     CDS             3484..4149
                     /locus_tag="VVR21_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6054276.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            4221..5447
                     /locus_tag="VVR21_000330"
     CDS             4221..5447
                     /locus_tag="VVR21_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6054277.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(5844..5921)
                     /locus_tag="VVR21_000331"
                     /pseudo
     CDS             complement(5844..5921)
                     /locus_tag="VVR21_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5992..6648
                     /locus_tag="VVR21_000332"
     CDS             5992..6648
                     /locus_tag="VVR21_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU6054278.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFAMLLGCSMGVVLDGQ
                     "
     gene            6638..6847
                     /locus_tag="VVR21_000333"
     CDS             6638..6847
                     /locus_tag="VVR21_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU6054279.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPTIVERFLKFL
                     PVSIIFALILSSVVTGKVGNLPPIK"
     gene            7065..7895
                     /locus_tag="VVR21_000334"
     CDS             7065..7895
                     /locus_tag="VVR21_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6054280.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            8049..8903
                     /locus_tag="VVR21_000335"
     CDS             8049..8903
                     /locus_tag="VVR21_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU6054281.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            9003..10376
                     /locus_tag="VVR21_000336"
     CDS             9003..10376
                     /locus_tag="VVR21_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU6054282.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            10369..11430
                     /locus_tag="VVR21_000337"
     CDS             10369..11430
                     /locus_tag="VVR21_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU6054283.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAILQAGVQLKVLKGVQ"
     gene            11432..12124
                     /locus_tag="VVR21_000338"
     CDS             11432..12124
                     /locus_tag="VVR21_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054284.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKTTSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(12154..12723)
                     /locus_tag="VVR21_000339"
     CDS             complement(12154..12723)
                     /locus_tag="VVR21_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6054285.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            12858..13472
                     /locus_tag="VVR21_000340"
     CDS             12858..13472
                     /locus_tag="VVR21_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU6054286.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            13474..15120
                     /locus_tag="VVR21_000341"
     CDS             13474..15120
                     /locus_tag="VVR21_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6054287.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            15132..16418
                     /locus_tag="VVR21_000342"
     CDS             15132..16418
                     /locus_tag="VVR21_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6054288.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVASVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            16479..17012
                     /locus_tag="VVR21_000343"
     CDS             16479..17012
                     /locus_tag="VVR21_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054289.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            17090..17560
                     /gene="nrdI"
                     /locus_tag="VVR21_000344"
     CDS             17090..17560
                     /gene="nrdI"
                     /locus_tag="VVR21_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU6054290.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(17853..19115)
                     /locus_tag="VVR21_000345"
     CDS             complement(17853..19115)
                     /locus_tag="VVR21_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU6054291.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(19425..19883)
                     /locus_tag="VVR21_000346"
     CDS             complement(19425..19883)
                     /locus_tag="VVR21_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU6054292.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNCLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(19880..20320)
                     /locus_tag="VVR21_000347"
     CDS             complement(19880..20320)
                     /locus_tag="VVR21_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6054293.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETTSQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            20676..22625
                     /gene="mutL"
                     /locus_tag="VVR21_000348"
     CDS             20676..22625
                     /gene="mutL"
                     /locus_tag="VVR21_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU6054294.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGYGISHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIAIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(22950..23417)
                     /locus_tag="VVR21_000349"
     CDS             complement(22950..23417)
                     /locus_tag="VVR21_000349"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU6054295.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(23418..24623)
                     /locus_tag="VVR21_000350"
     CDS             complement(23418..24623)
                     /locus_tag="VVR21_000350"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU6054296.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(24643..25278)
                     /gene="ribE"
                     /locus_tag="VVR21_000351"
     CDS             complement(24643..25278)
                     /gene="ribE"
                     /locus_tag="VVR21_000351"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU6054297.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(25263..26363)
                     /gene="ribD"
                     /locus_tag="VVR21_000352"
     CDS             complement(25263..26363)
                     /gene="ribD"
                     /locus_tag="VVR21_000352"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU6054298.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(26496..26610)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            26767..27360
                     /gene="ruvA"
                     /locus_tag="VVR21_000353"
     CDS             26767..27360
                     /gene="ruvA"
                     /locus_tag="VVR21_000353"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU6054299.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            27370..27933
                     /locus_tag="VVR21_000354"
     CDS             27370..27933
                     /locus_tag="VVR21_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU6054300.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAILENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWRGLK"
     gene            27930..28607
                     /locus_tag="VVR21_000355"
     CDS             27930..28607
                     /locus_tag="VVR21_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6054301.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(28762..29793)
                     /locus_tag="VVR21_000356"
     CDS             complement(28762..29793)
                     /locus_tag="VVR21_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU6054302.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(30048..30731)
                     /locus_tag="VVR21_000357"
     CDS             complement(30048..30731)
                     /locus_tag="VVR21_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU6054303.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(30743..31687)
                     /locus_tag="VVR21_000358"
     CDS             complement(30743..31687)
                     /locus_tag="VVR21_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6054304.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            31819..34650
                     /gene="uvrA"
                     /locus_tag="VVR21_000359"
     CDS             31819..34650
                     /gene="uvrA"
                     /locus_tag="VVR21_000359"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU6054305.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            34643..35704
                     /locus_tag="VVR21_000360"
     CDS             34643..35704
                     /locus_tag="VVR21_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6054306.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            35836..36234
                     /gene="spx"
                     /locus_tag="VVR21_000361"
     CDS             35836..36234
                     /gene="spx"
                     /locus_tag="VVR21_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU6054307.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            36300..36869
                     /locus_tag="VVR21_000362"
     CDS             36300..36869
                     /locus_tag="VVR21_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6054308.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            36956..37222
                     /locus_tag="VVR21_000363"
     CDS             36956..37222
                     /locus_tag="VVR21_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU6054309.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            37226..37645
                     /gene="ruvX"
                     /locus_tag="VVR21_000364"
     CDS             37226..37645
                     /gene="ruvX"
                     /locus_tag="VVR21_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU6054310.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            37661..37966
                     /locus_tag="VVR21_000365"
     CDS             37661..37966
                     /locus_tag="VVR21_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU6054311.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            38174..39424
                     /locus_tag="VVR21_000366"
     CDS             38174..39424
                     /locus_tag="VVR21_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6054312.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            39421..39966
                     /locus_tag="VVR21_000367"
     CDS             39421..39966
                     /locus_tag="VVR21_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU6054313.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTLDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            40112..41644
                     /gene="cls"
                     /locus_tag="VVR21_000368"
     CDS             40112..41644
                     /gene="cls"
                     /locus_tag="VVR21_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU6054314.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            41902..43440
                     /locus_tag="VVR21_000369"
     CDS             41902..43440
                     /locus_tag="VVR21_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6054315.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            43560..45767
                     /gene="nrdD"
                     /locus_tag="VVR21_000370"
     CDS             43560..45767
                     /gene="nrdD"
                     /locus_tag="VVR21_000370"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU6054316.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            45779..45919
                     /locus_tag="VVR21_000371"
     CDS             45779..45919
                     /locus_tag="VVR21_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054317.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            45963..46469
                     /locus_tag="VVR21_000372"
     CDS             45963..46469
                     /locus_tag="VVR21_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054318.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            46462..47052
                     /gene="nrdG"
                     /locus_tag="VVR21_000373"
     CDS             46462..47052
                     /gene="nrdG"
                     /locus_tag="VVR21_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU6054319.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            47049..47666
                     /locus_tag="VVR21_000374"
     CDS             47049..47666
                     /locus_tag="VVR21_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU6054320.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            47942..48250
                     /gene="rpsJ"
                     /locus_tag="VVR21_000375"
     CDS             47942..48250
                     /gene="rpsJ"
                     /locus_tag="VVR21_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU6054321.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            48467..49093
                     /gene="rplC"
                     /locus_tag="VVR21_000376"
     CDS             48467..49093
                     /gene="rplC"
                     /locus_tag="VVR21_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU6054322.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            49118..49741
                     /gene="rplD"
                     /locus_tag="VVR21_000377"
     CDS             49118..49741
                     /gene="rplD"
                     /locus_tag="VVR21_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU6054323.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            49741..50037
                     /locus_tag="VVR21_000378"
     CDS             49741..50037
                     /locus_tag="VVR21_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU6054324.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            50055..50888
                     /gene="rplB"
                     /locus_tag="VVR21_000379"
     CDS             50055..50888
                     /gene="rplB"
                     /locus_tag="VVR21_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU6054325.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            50992..51273
                     /gene="rpsS"
                     /locus_tag="VVR21_000380"
     CDS             50992..51273
                     /gene="rpsS"
                     /locus_tag="VVR21_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU6054326.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            51285..51629
                     /gene="rplV"
                     /locus_tag="VVR21_000381"
     CDS             51285..51629
                     /gene="rplV"
                     /locus_tag="VVR21_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU6054327.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            51642..52295
                     /gene="rpsC"
                     /locus_tag="VVR21_000382"
     CDS             51642..52295
                     /gene="rpsC"
                     /locus_tag="VVR21_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU6054328.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            52299..52712
                     /gene="rplP"
                     /locus_tag="VVR21_000383"
     CDS             52299..52712
                     /gene="rplP"
                     /locus_tag="VVR21_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU6054329.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            52722..52928
                     /locus_tag="VVR21_000384"
     CDS             52722..52928
                     /locus_tag="VVR21_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU6054330.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            52953..53213
                     /gene="rpsQ"
                     /locus_tag="VVR21_000385"
     CDS             52953..53213
                     /gene="rpsQ"
                     /locus_tag="VVR21_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU6054331.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            53239..53607
                     /gene="rplN"
                     /locus_tag="VVR21_000386"
     CDS             53239..53607
                     /gene="rplN"
                     /locus_tag="VVR21_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU6054332.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            53685..53990
                     /gene="rplX"
                     /locus_tag="VVR21_000387"
     CDS             53685..53990
                     /gene="rplX"
                     /locus_tag="VVR21_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU6054333.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            54014..54556
                     /gene="rplE"
                     /locus_tag="VVR21_000388"
     CDS             54014..54556
                     /gene="rplE"
                     /locus_tag="VVR21_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU6054334.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            54574..54843
                     /gene="rpsN"
                     /locus_tag="VVR21_000389"
     CDS             54574..54843
                     /gene="rpsN"
                     /locus_tag="VVR21_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU6054335.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            55128..55526
                     /gene="rpsH"
                     /locus_tag="VVR21_000390"
     CDS             55128..55526
                     /gene="rpsH"
                     /locus_tag="VVR21_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU6054336.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            55718..56254
                     /gene="rplF"
                     /locus_tag="VVR21_000391"
     CDS             55718..56254
                     /gene="rplF"
                     /locus_tag="VVR21_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU6054337.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYIGEFVRRKEGKTGK"
     gene            56338..56694
                     /gene="rplR"
                     /locus_tag="VVR21_000392"
     CDS             56338..56694
                     /gene="rplR"
                     /locus_tag="VVR21_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU6054338.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            56712..57206
                     /gene="rpsE"
                     /locus_tag="VVR21_000393"
     CDS             56712..57206
                     /gene="rpsE"
                     /locus_tag="VVR21_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU6054339.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            57178..57402
                     /gene="rpmD"
                     /locus_tag="VVR21_000394"
     CDS             57178..57402
                     /gene="rpmD"
                     /locus_tag="VVR21_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU6054340.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            57547..57987
                     /gene="rplO"
                     /locus_tag="VVR21_000395"
     CDS             57547..57987
                     /gene="rplO"
                     /locus_tag="VVR21_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU6054341.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            58000..59310
                     /gene="secY"
                     /locus_tag="VVR21_000396"
     CDS             58000..59310
                     /gene="secY"
                     /locus_tag="VVR21_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU6054342.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            59461..60099
                     /locus_tag="VVR21_000397"
     CDS             59461..60099
                     /locus_tag="VVR21_000397"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU6054343.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMVNQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            60216..60434
                     /gene="infA"
                     /locus_tag="VVR21_000398"
     CDS             60216..60434
                     /gene="infA"
                     /locus_tag="VVR21_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU6054344.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            60459..60575
                     /gene="rpmJ"
                     /locus_tag="VVR21_000399"
     CDS             60459..60575
                     /gene="rpmJ"
                     /locus_tag="VVR21_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU6054345.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            60593..60958
                     /gene="rpsM"
                     /locus_tag="VVR21_000400"
     CDS             60593..60958
                     /gene="rpsM"
                     /locus_tag="VVR21_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU6054346.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            60976..61359
                     /gene="rpsK"
                     /locus_tag="VVR21_000401"
     CDS             60976..61359
                     /gene="rpsK"
                     /locus_tag="VVR21_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU6054347.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            61402..62337
                     /locus_tag="VVR21_000402"
     CDS             61402..62337
                     /locus_tag="VVR21_000402"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU6054348.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            62349..62735
                     /gene="rplQ"
                     /locus_tag="VVR21_000403"
     CDS             62349..62735
                     /gene="rplQ"
                     /locus_tag="VVR21_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU6054349.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            63000..63266
                     /locus_tag="VVR21_000404"
     CDS             63000..63266
                     /locus_tag="VVR21_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU6054350.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            63276..64613
                     /locus_tag="VVR21_000405"
     CDS             63276..64613
                     /locus_tag="VVR21_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU6054351.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            64857..65549
                     /locus_tag="VVR21_000406"
     CDS             64857..65549
                     /locus_tag="VVR21_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6054352.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGTG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(65652..67287)
                     /locus_tag="VVR21_000407"
                     /pseudo
     CDS             complement(65652..67287)
                     /locus_tag="VVR21_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(67277..68368)
                     /locus_tag="VVR21_000408"
                     /pseudo
     CDS             complement(67277..68368)
                     /locus_tag="VVR21_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(68381..69502)
                     /locus_tag="VVR21_000409"
                     /pseudo
     CDS             complement(68381..69502)
                     /locus_tag="VVR21_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(69719..69862)
                     /locus_tag="VVR21_000410"
     CDS             complement(69719..69862)
                     /locus_tag="VVR21_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6054353.1"
                     /translation="MAESPNSPLSAISDQVGFSDYKYFAKVFKKYLHISPKKLKSLGR
                     IVK"
     gene            complement(70243..70470)
                     /locus_tag="VVR21_000411"
     CDS             complement(70243..70470)
                     /locus_tag="VVR21_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEU6054354.1"
                     /translation="MFKLIIVEDEHLIRKWLEIAVDYSALGIQVVGTASHGQEGMKLI
                     QEKEPHICLNRHHNANYGCFYDVQSHSYSFL"
     gene            complement(70474..70857)
                     /locus_tag="VVR21_000412"
     CDS             complement(70474..70857)
                     /locus_tag="VVR21_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6054355.1"
                     /translation="MIHKIRFEQFSYDIVCPETVDNQPIPKLFLLPLVENAIKHGMQY
                     RIDLHIDIHITLEADSLTFLVKDNAEGLTKQERFAILDSLESPHTQHGIVNSYKRLSN
                     FFSDVQLDLGVNRQGETWVKFVTKD"
     gene            complement(71190..71966)
                     /locus_tag="VVR21_000413"
     CDS             complement(71190..71966)
                     /locus_tag="VVR21_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU6054356.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            72088..72834
                     /locus_tag="VVR21_000414"
     CDS             72088..72834
                     /locus_tag="VVR21_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6054357.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            72847..73827
                     /locus_tag="VVR21_000415"
     CDS             72847..73827
                     /locus_tag="VVR21_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU6054358.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNVGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECIFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            74022..74342
                     /locus_tag="VVR21_000416"
     CDS             74022..74342
                     /locus_tag="VVR21_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6054359.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            74388..74696
                     /locus_tag="VVR21_000417"
     CDS             74388..74696
                     /locus_tag="VVR21_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6054360.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            74713..76011
                     /locus_tag="VVR21_000418"
     CDS             74713..76011
                     /locus_tag="VVR21_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6054361.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
BASE COUNT        22938 a        13853 c        16502 g        22848 t
ORIGIN      
        1 aatattactt tttttgatac attttctgaa attaaaaata atattgatta ttatattatt
       61 gcgcttccga cagattatga tgagaaaatt ggtagtttta atacatatga aatcgaacaa
      121 acggtatcga agattctgag ggtaaaacct aatggaaaga ttattttaaa gtcaacagtt
      181 ccgatcggct tttcaaacaa attaaaaagg ctgtttgata caaaaaatat catttttgtc
      241 cctgaatttt tgagagaagg ttgttctata tatgataatt tatatccaag tcgcatagtt
      301 gttggagatg agacagttga aggaagaaaa attgcagagt tgttcctttc gattagtact
      361 catagtactg ccaatattaa aaatgttatg ttagtttctc ctactgaagc agaagcaatt
      421 aagctttttt ctaacacatt cttagctctc cgtgttgctt tttttaatga actagattct
      481 tttgctgaga ggagaagttt aaatgctgaa gttgtaataa aaggtgtttg tttagatcca
      541 agaattggaa atttttataa taatccttct tttggatttg gaggatattg tcttcccaaa
      601 gatactaaac aattaaaaaa agaatttata gaaataaatg ccccagtgat agaagcgatt
      661 gatatttcaa acacaaatag aaaacagttc atagttaaac aaatattgga acgaaagcca
      721 aagatagtag gaatatataa attggggatg aaatataatt cagataatta caaagagtca
      781 gctattttaa gtataattaa tgaactattg attgtcggta taaaaatttt agtatatgaa
      841 ccaaatttaa acgttagtat agataacgta atttttgaaa agaattttga actatttaca
      901 aaacaaagtg atctaattgt tgcaaataga tgggataggg gccttgaagc ttataaagat
      961 aaagtttaca caagggggat ctggataaga gattaactat tgatattaaa gaggcaataa
     1021 tttataaaat ttgtacaaaa aaatgttaaa ttttcacatt ttcatagtat actgtttaat
     1081 agaaagtagg ttctttgtaa ccgctccatt ataaaatcct ttcactcttc cggtatacta
     1141 ttaggaaaaa cataactgga ggatattttg agctcacacc tcatcgttcc agtggctgtt
     1201 ccccaagctc gtgtactgcc caaaaaagtt agacattcta tttagaacga ggattgagtt
     1261 ctgtattgta caaggctcgg tccttttaga gtcagcttaa ggctggcttt ttcaatcacc
     1321 aaagtgtcag aatgttttga caaatgaaca caaataatga tataatatgc aaaagctagg
     1381 aggtggtagg atgattgaaa aaatggaact gggggaattt tacaaggaat tgcgcttggc
     1441 gagaaagctc aagcagtcag atgtggcttg tgctggacta acagcctctc agttgtccaa
     1501 gtttgaacta ggacagtcta tgctgtctgc agacaagctg atcctagcca tccaagggat
     1561 caatatgaat tttgatgagt ttgggcacaa actcaacaac tatcaagaat ctccacatat
     1621 gcgaattggt agaagggttg tggattgctt ttcccatcag gatatagctg ctttagagca
     1681 gctattggag ggagtcgatc aagaacagat ggcgcagacc tatcgtcgtt tgaatgccat
     1741 tgtgattaaa aatgcactcc attccttaga taaaagctac ccgctaacag aggaggatag
     1801 cgagtttttg actacctacc tctacgctat tgagtcttgg acctggtttg aactctatct
     1861 tttttgcaat actatgccct tcttgagcaa tcaagatctg atctttttat caacctcctt
     1921 actcgaaaaa tccaaggaat ttaaagagtt agtacacaat cgatggtata tgaaaagtgg
     1981 ttatcttaat atcatctcag aacttatgga gcgcaagcta ttttcttata ttccaatctt
     2041 tgaagctgag ctggagcgca tgctccgtcc atacgatgtt tttgaaaaag tattgtggca
     2101 gtttttaaag aagatgagca ttttccttca aaccaaagga agcaatcaaa aagagattga
     2161 acactttatc caatctctgc aagtattaga aaatccacaa ttgacagccc tttttgaatt
     2221 gcgtttgcag caatacaaag agcttatcga ttagttagaa atgggaaaaa gataataata
     2281 tcagcaacga tcgtcaataa tgttaaaact tgtttcttca tattacttcc ctcctcatta
     2341 gtaataactt tattatacca gggaaataat caaatctacc aaaatcgcaa atctgaaatt
     2401 tctataagaa aaaatatcaa atatgcgatt ttctaaaata agccaatttc cgtgttatac
     2461 tgtccttgta aaacatttga agcaaatcct aggtcgcaga agtggtttac aaatgaagat
     2521 aattgaagga gtgtaaaaga tgttaaattt acaatttgca gaaacaatgg aattgacaga
     2581 agctgagttg caagatgtta gaggaggcaa cctcgtaaat tctatgggag gtggtggaag
     2641 aagtggtata tctggttggg gcgtcccagg aatttaccct ggttggggca atcaagggat
     2701 gagtcctaat cgtggagctt ttgattggac tatagattta gcagatggat tgtttggccg
     2761 ccgtagaaga taggctctta taggagataa taggatgaag aaaatgaaag aagtgaaatt
     2821 tcacctagca actggcttgt tgattttgac ttattacctc atttttaatg tcacatcaga
     2881 cttagatttt atggttgctt tgtctgataa tatgtactat gtgttccaag ttttattggt
     2941 acttattctg ggaactatag ctacaattgc ttttgtcaaa agtgaacatt ggaaagagtg
     3001 tggtcgtttc cagtttcgtt ggtcttacct gggtgttttc cttctttctt ttttcttatt
     3061 gttcgtgtgg gcaaatctaa caacctatat ctttcctcgt acccagaatg gaagtacagt
     3121 cgtagaagta gccaccagtt taacaggaat tagctatttt gttacgcgaa tactttatac
     3181 tagtattatc gcacctgtat cagaagaggt tgtttgtcgt ggtcttttga tgacaagttt
     3241 atctaaagtt aagagatact atcttgatgt tcttgtttcc gctgccatat ttggcgctat
     3301 gcatgttttg cagtatggtt ggataacgac agatttcata aagtattttg gaatgggctt
     3361 gatattttgt atgatgtttc gctacacccg atccatctat tgggctatag ctctgcatgc
     3421 ttcatggaat agcttcttac tcattgttac tttattggta tttggatatt agaaaggtga
     3481 tatatgaaaa agataatctc acaccgctac tttattatag tttttctact agttattgct
     3541 gaccagaagt tcagtgtttt agttttacgc agcgaccttg ttgctgggct atctgacttt
     3601 gcctattatc tgtcggatat gatgttgaat tttcttgtgg ttttatttgc tcttattgct
     3661 atgatttggt cggggaaatg gcagaaaatc aatagtagaa agtttaaagg atcctatctt
     3721 ttctattcct tcctagctct gcttgctttt gttgcttgga attttgtcac cttttttctt
     3781 ttcccaccta ctcgaaatga aatttcttat caacatgctg ctcctacttt tacaggagct
     3841 acggcatttt tgatgtattt tttttatcct gtgattgcag gtcccatttt tgaagacatg
     3901 atttatcgtg gattagtgat gactgctctg gaaaaaggaa agaaatgggg gctagatgta
     3961 cttggttccg ctgttttatt tggggtctcg cacattagta atcacggttg ggtcttgaca
     4021 gactttgtct tctatatggg tggaggtctt atatttgcag tcttatttag aatgacaaag
     4081 tcaatttatt ggcctattgg actgcatata gtctacaatg gtattggtca gcttttgatg
     4141 ttactgtaat tttggttgtt agtagtatcg cggtctattc ttggggaaag attcccattt
     4201 gaatttaaaa aggagttgta atgaaagtat ttcttcaaaa tagagatttt aggcaattaa
     4261 ctatcaacca gtggatttca acgcttgggg atacgatttt ttatctggcc ttcctgaatt
     4321 atgtggcaga tgcgtctttt gcccctttgg cgattttact cattacgatt tcagaaaccc
     4381 ttccccaaat tttacaaatc tttctgggag ttttggcaga ttttcaacat catcgtgtct
     4441 tgaaatacac agtcattagt tttgcaaaat ttttgcttta ctctatcgtt tctttatcac
     4501 tttcagggca gtctttctcc ttgttgctag tagcatttat ttgtctgatt aacctcttgt
     4561 ctgacacatt gagttacttt tcaggagcca tgctcactcc gattttcatt agaattattg
     4621 ggcaagacca tctggcagaa gctattggat ttaaacagtc aactgttagt ttagtgaaaa
     4681 caatcagtaa tattctagga ggagtcttgc tagggattct ctccatccag ttcatttcct
     4741 tgctgaacgc tcttaccttt ttaatcgcat ttttaggtat ccttttcata aaaactgacc
     4801 tcttgaaagt agaaaaaacg attaactatc aagaaggact ctctgtaaaa tccttttgcc
     4861 agcatttgct ccaatcatcg aaattgatat ggaatatgaa taaggtgctc ttggttttgt
     4921 ttattatctc tactagtcaa gcagtgataa atgttacagt tcctgtctct actctatttt
     4981 tgaggaatca accctttttg aatttacaaa caggtcaatc tcttgccttg ctatccactt
     5041 ttgaactgtc agccctgatt gtcggaagcc ttgtaagtgg ctatctgcaa cataccattt
     5101 ccataaaaac agctctctat gcctcacttg tcatccagtt gcttcttcta gtaggatttg
     5161 ccacagttcg ttttgactgg attctcatct ttagtacctt ggatgccttt ttcgcaggtg
     5221 ttctctctcc tagattgcaa gaactcgttt ttaaacaaat acctgaggag tcaatgggag
     5281 cagttcaatc ctctatcggt gccattacgg ttgttttacc tagcttattt acaatagctt
     5341 tggtaaccat tgctactagc tttggaactc tggcagttag ctttgtttta ttgctatttc
     5401 ttctagttgc ctttgttatg cttctgaata ttcgtgaaag tatttagtgg agaatttcta
     5461 taatatatgt ttgagactgg atttccagtc tttttatgat ggtcaaaatc aacagacttt
     5521 tttctctttt ctgaatgtgt tataatagac tgaatctaaa atagtacgaa acaattgcta
     5581 aaacatttat agaaattaat tttactttcc caatcgattt gttctcatct tatttcaatc
     5641 tgctatataa tagtccatgc tgtggctgga ttcttttcag cctacttgta ctcttcgaaa
     5701 ctctcttcaa accacgtcag cttcactttg ccgtaggtat ggttactgac ttcgtcagtt
     5761 ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
     5821 aaacagtgtt ttgagctgac ttcatcagtt ctatctgcaa cctcaaaaca gtgttttgag
     5881 caacctgcgg ctagtttcct agtttgctct ttgattttca ttgagtatta ttaagacaat
     5941 atgaggagaa agatgaaaga aaaaggattt taggaggggg cgcaggcagc catgccaacg
     6001 gctctgggct atgtcagtat cggcctggcc tgtgggacta tcggtgcgcc ctatgtgaca
     6061 cctgttgaga tgggcttgat gagtctcttt gtttatgctg ggagtgccca gtttgccatg
     6121 ttggcactga ttgtggttca agctcctgtg gcagctattg ctatgacggt ttttctaatc
     6181 aacttgcgtc tctttttgtt gagtttacac gcatcgactt atttccgtca taccagtctt
     6241 tggtacaata tcggtatgtc tagtatcttg acagatgaga cctatggcgt tttgatgggt
     6301 gaattggccc atacagacaa ggtaaatcct atgtggatgc acggaaacaa tcttaacagc
     6361 tatgtggctt ggtttgtggg gacagtagtc ggaacggctc tgggtggcct gctaccaaat
     6421 ccagaaatct ttggcttgga ttttgccctg gttgggatgt ttattggtat ttttgcttcg
     6481 caatttcaga tgatgcaaag acggattcct gttcgcaatc tgctcattat cttagcagtt
     6541 gttgcggtgt ccttcttttt acttttgaca gtggtgtctc agtcactagc tgttctgttt
     6601 gcgatgctac ttggttgtag catgggggtg gttttagatg gtcagtaagt atcttttatt
     6661 agcggttatt ttctctggtc ttgtgacctg gattccccgt atgattccct tcatcttggt
     6721 caagtataag ggcctgccta cgattgttga gcgttttttg aagtttttgc ctgtttccat
     6781 tatctttgcc ttgattcttt caagtgtagt gacaggtaag gttgggaacc ttcctccaat
     6841 caaatgactg gacttcttag cagtctttcc aatagcttgg gtagcctttc gctaccgcaa
     6901 tctagtcgga acagttctct ttggagtggt cttgattgcc atcttgcgtt tggtctttta
     6961 aattacccat aaaaaaaact tatcacagag atagatatca tataatggcg taaatgctct
     7021 ttttctgtta agattataag gtattctatt ttggaggaaa tgacatgaaa aaaatcgtta
     7081 aatactcatc tcttgctgcc ctaggacttg ttgctgcagg tgtgcttgcg gcttgctcag
     7141 ggggtgctaa gaaagaagga gaagcagcta gcaagaaaga aatcatcgtt gcaaccaatg
     7201 gatcaccaaa gccatttatc tatgaagaaa atggcgaatt gactggttat gagattgaag
     7261 tcgttcgcgc tatctttaaa gattctgaca aatataatgt caagtttgaa aagacagaat
     7321 ggtcaggtgt ctttgctggt cttgatgctg accgttacaa tatggctgtc aacaatctta
     7381 gctacactaa agaacgtgcg gagaaatacc tctatgccgc accaattgcc caaaatccta
     7441 atgtccttgt cgtgaagaaa gatgactcta gtatcaagtc tctcgatgat atcggtggaa
     7501 aatcgacgga agtcgttcaa gccactacat cagctaagca gttagaagca tacaacgctg
     7561 aacacacgga caacccaact atccttaact atactaaggc agacttccaa caaatcatgg
     7621 tacgtttgag cgatggacaa tttgactaca agatttttga taaaatcggt gttgaaacag
     7681 ttatcaagaa ccaaggtttg gacaacttga aagttatcga acttccaagc gaccaacaac
     7741 cgtacgttta cccacttctt gctcaaggtc aagatgagtt gaaatcgttt gtagacaaac
     7801 gcatcaaaga actttataaa gatggaactc ttgaaaaatt gtctaaacaa ttcttcggag
     7861 acacttatct accggcagaa gctgatatta aataatttct tgaaatcatc cattctgagt
     7921 aaggtgggtg gtttctcagt ttttagggat atagttttaa actatatatc tgactatcta
     7981 ataacaattt gtgaaatcaa acaaattgtg agatactagt acggtattat ttttaaggag
     8041 aaagaatcat gaaaatcaaa aaatggcttg gtctagcagc ccttgctaca gtcgcaggtt
     8101 tggctcttgc agcttgcgga aactcagaaa agaaagcaga caatgcaaca actatcaaaa
     8161 tcgcaactgt taaccgtagc ggttctgaag aaaaacgttg ggacaaaatc caagaattgg
     8221 ttaaaaaaga cggaattacc ttggaattta cagagttcac agactattca caaccaaaca
     8281 aagcaactgc tgatggcgaa gtagatttga acgctttcca acactataac ttcttgaaca
     8341 actggaacaa agaaaacgga aaagaccttg tagcgattgg agatacttac atctctccaa
     8401 tccgccttta ctcaggtttg aatggaagtg ccaacaagta cactaaagta gaagacatcc
     8461 cagcaaacgg agaaatcgct gtaccgaatg acgctacaaa cgaaagccgt gcgctttact
     8521 tgcttcaatc agctggcttg attaaattgg atgtttctgg aactgctctt gcaacagttg
     8581 ccaacatcaa agaaaatcca aagaacttga aaatcactga attggacgct agccaaacag
     8641 ctcgttcatt gtcatcagtt gacgctgccg ttgtaaacaa taccttcgtt acagaagcaa
     8701 aattggacta caagaaagca cttttcaaag aacaagctga tgaaaactca aaacaatggt
     8761 acaacatcat tgttgcgaaa aaagattggg aaacatcacc taaggctgat gctatcaaga
     8821 aagtaatcgc agcttaccac acagatgacg tgaaaaaagt tatcgaagaa acatcagacg
     8881 gtttggatca accagtttgg taataagaaa cagggaggtg ggagagagaa ttccacctct
     8941 tgcttttgta tagagcacgg agtgtaaaga agactattcg ttcatagaaa ggtagagaga
     9001 atatggtttt tcctagcgaa caagaacaga ttgaaaaatt tgaaaaggat catgtagccc
     9061 agcattattt tgaggttttg cgtaccttga tttctaagaa atcagtcttt gcccagcagg
     9121 ttggactcaa ggaagtcgca aattatctgg gtgagatttt caagcgtgtt ggagctgaag
     9181 tggagattga tgagagctat acagcgcctt ttgtcatggc acatttcaag agttcgcgtc
     9241 cagatgccaa gaccttgatt ttctataacc actatgacac tgtgccagcg gatggggatc
     9301 aggtctggac agaggatcct tttacgcttt cggtccgcaa tggcttcatg tatgggcgtg
     9361 gggttgatga cgacaagggt catatcacag ctcgcttgag tgctttgaga aaatatatgc
     9421 agcaccatga tgatttacct gtcaatatca gctttatcat ggagggagcg gaggaatcgg
     9481 cttcaacaga cctagataag tatttggaaa agcatgcaga caaactccgt ggggcggatt
     9541 tgttggtctg ggaacaaggg accaaaaatg ccttggaaca gctggaaatt tctggtggca
     9601 ataaggggat tgtgaccttt gatgccaagg taaaaagcgc tgatgtggat atccactcga
     9661 gttatggtgg tgttgtggaa tcagctcctt ggtatctcct ccaagcctta cagtctcttc
     9721 gtgctgcgga tggccgtatc ttggttgaag gcttgtacga agaagtacaa gagcccaatg
     9781 aacgagaaat ggccttgcta gaaacttatg gtcaacgaaa cccagaggaa gttagtcgga
     9841 tttatggatt ggagttgcct ctcttacagg aggagcggat ggcctttcta aaacgtttct
     9901 ttttcgagcc agcgcttaat atcgaaggaa tccagtctgg ttatcaaggt cagggtgtta
     9961 agactatttt acctgcagaa gccagtgcca agctagaggt tcgtctggtt ccgggcctag
    10021 aaccgcatga tgttctggaa aaaattcgga aacaactaga caaaaatggc tttgataagg
    10081 tagaattata ctataccttg ggagagatga gctatcgaag cgatatgagc gcaccagcca
    10141 ttctcaatgt gatcgagttg gccaagaaat tctatccaca gggcgtttca gtcttgccga
    10201 cgacagcggg gacaggacct atgcatacgg tctttgatgc cctagaggta ccaatggttg
    10261 cattcggtct aggaaatgcc aatagccgag accacggtgg agatgaaaat gtgcgaatcg
    10321 ctgattatta cacccatatc gaattagtag aggagctgat tagaagctat gagtagagat
    10381 attatcaagt tagatcagat cgatgtgact tttcaccaaa agaagagaac catcacagcg
    10441 gttaaggatg tgaccattca catccaagaa ggggatatct acggaatcgt tggatattct
    10501 ggagcaggga aatcaaccct tgtacgggtg attaacctct tgcaaaaacc atctgcaggg
    10561 aaaattacca ttgacgacga tgtgattttt gatggtaagg tcaccttgac ggcagagcag
    10621 ttgcgtcgta aacgtcaaga tatcgggatg attttccagc attttaacct gatgagccaa
    10681 aagacagcag aggagaatgt agcctttgcc cttaaacact ctggactcag caaggaagaa
    10741 aagaaggcta aagtagctaa gttgttggac ttggttggtt tggcagatcg tgctgaaaac
    10801 tacccttcac aactatctgg agggcaaaaa cagcgtgtgg caattgcgcg tgccttggcc
    10861 aatgatccaa aaatcttgat ttcagacgag tcaacttctg cccttgaccc taagacaacc
    10921 aagcagattt tggccttgtt gcaagatttg aaccaaaaat taggcttgac agttgtcttg
    10981 attacgcatg aaatgcagat tgtcaaagac attgccaacc gtgtggcggt tatgcaggat
    11041 gggcatttga ttgaagaggg aagtgtcctt gaaatcttct caaaccctaa acaacctttg
    11101 actcaagact ttatctcaac agccacaggt attgacgaag ccatggtcaa aatcgagaag
    11161 caagaaatcg tggaacactt gtctgaaaac agtctcttgg tgcaactcaa gtacgctgga
    11221 gcttcaacag acgagccact tttgaatgaa ttgtacaagc attaccaagt aatggctaat
    11281 attctctatg ggaatatcga aattctcgat ggtactcctg ttggagaatt ggtggtggtc
    11341 ttgtcaggtg aaaaagcagc gttggcaggt gcccaagaag ctattctcca agcaggtgta
    11401 caactaaaag tattgaaggg agtacagtaa gatggaatca ttgattcaaa cctatttacc
    11461 aaatgtctat aaaatgggtt gggctggtca ggcaggctgg ggaacggcta tctacttaac
    11521 tctttatatg acagttcttt ccttcattat cggaggcttc ttggggctag tggcaggtct
    11581 ctttctcgtc ttgacagcgc caggtggtgt cttggagaat aaagtcgtct tctggatttt
    11641 agacaaaact acctcaattt ttcgtgcagt tccctttatc atcctcttgg caatcttgtc
    11701 accactttct cacttgattg ttaaaacaag tatcgggcca aatgcagccc ttgtcccact
    11761 ttcttttgca gtctttgcct tctttgcccg tcaggtgcag gttgtcttgg ctgaattgga
    11821 tggcggtgtc attgaggcgg ctcaagcgag cggagcgact ttctgggaca tcgtgggtgt
    11881 ttacctatca gaaggtcttc cagatttgat ccgtgtgacg actgtgacct tgatttccct
    11941 tgttggggaa acagctatgg ccggtgcggt tggagctggt ggtatcggta acgtagccat
    12001 cgcttatgga tttaaccgct acaatcacga tgtgaccatc ttggcaacca tcattatcat
    12061 tttgattatc tttgcaatcc aattcttggg agatttcttg actaagaaat tgagccataa
    12121 ataaaaaaga gccgcgtggc tctttttaac tgatcagatt ttctgtgcaa attttttact
    12181 caaggcttgt ccaatcaagg cacccactag ggctccgatg acaatacttg cgataaatag
    12241 aaggacagtt ccagggtttg gagcgaccat gatgcggtcg atatattctt gggattttcc
    12301 tcttgccaga agagtagcca tataggcttt gggcgcaatc cacataagca agattggtcc
    12361 tgttgtacta aaggcgaaaa taatgaaaga aaggaagttc tttgttttgt ccttgtattt
    12421 tcctaaatga gctacttcat ctgctaggag gccacagata attccaggaa ggaaggaacc
    12481 agcaccgtgt ttagttccca agaaaaagag ggcaatgaca aggccgatag tggtaatggc
    12541 tccaaagcgc ggaacttttg cgactaggat catatagacg ctaccgccga caagggcagt
    12601 aaaggcaggc gcataaaaca tgtttccagt ttggtcaaag agattgccca aaaggacacc
    12661 aatccccatg cagaggaagt aaagaactgc aaaaagcagt gtagttaaga tagatttctt
    12721 catgaattgt ctcctgataa ttttttcaca attctcattt taccatggtt tggtgggatt
    12781 gtaaatggat actagaagtt tttgaaaacg cttgaaatat gatataatgg tttcatagtt
    12841 atttttaggg gaatatcatg ggtagatttt tagactttgt ctttaatcgt ttctttttag
    12901 ggatgattgc gacagccttc ttttggctat taactttagc aggagggatt atccttggtc
    12961 tagcgccggc tagtgccacc ttgatgagct tatatgcaga acatggttat agctttcggg
    13021 aatacagttt gaaggaggct tggtctcttt acaagcaaaa ttttgtctca agcaacctga
    13081 ttttctatag ctttttaggt gtgggtctag ttttgaccta tggtttgtat ctcttggtgc
    13141 aattgcctca tcagaccatt gttcatttga ttgcgaccct tttgaatgtc ctagtagttg
    13201 ccctgatctt tttggcttat acagtatctt taaaattaca agtttatttt gccttgtcct
    13261 atcgaaatag tctcaaatta tccttgattg gcatctttat gagtctagca gctgtggcca
    13321 aggttctcct tgggactgtg ctacttgtag caattggtta ctatatgcct gccctgctat
    13381 tttttgtagg aattgggatg tggcatttct ttatcagtga tatgttggaa cctgtctatg
    13441 aaatcatcca tgaaaaattg gcgacaaaat agaatgaagc acttttggct acatacgctt
    13501 ctaagaacct atagttcagt gatgatcatt atcattgcga gttttgcaat cttactctct
    13561 tacgctgact gggattcacg tgaaaaggaa gcccagagag tagcccagcg tgtaactgct
    13621 agaacagtga gtgaaattga atattaccat agagagtcaa cccagatagc tcaggcttta
    13681 gttgaaaatc aagctcgtat cgagggaatc tataaatact ttagccttag catgccagac
    13741 tatttttact ggcaattaga gcggaaagct tcgccttata tatcagtctc tctgtatgaa
    13801 aatgttgatg acctctatgt tcgaaatgat tttgtaactg gggtggccat tgcttttcaa
    13861 gattacaagg aagtctatgt ttctactaaa gacaaacgta gtggagaaaa aatcagggct
    13921 gaggatttca aaccagcagg aaatagtttt gccattccag tgtcagatcc agtgtcagat
    13981 caagacttag gagtgattta catctccttg gatcctgctg ttctatacca tgccattgat
    14041 aatactagag gtcatactcc gatggcagta acagtgacct caccttttga tacggagatt
    14101 tttcatattg gtgagacagt tgataaggag agtgaaaatt ggctagttgg cttaacttct
    14161 catggttatc aggttcaggt ggcagttccc aaaaactttg ttttacaagg aacggtgacc
    14221 agctctgctt tgattgtggg cttgagcctt ctctttattg tcattcttta tctgactttg
    14281 aggcagacct ttgctaatta tcaaaagcag gtagtggatt tggtggattc catccaagct
    14341 attgcccaag gacaagaagg tcttcgcatt gatacgcttg aaaaggatca ggaattgctc
    14401 ctaatcgcgg agacgaccaa tgatatgttg gatcgattgg aaaagaatat ccatgatatt
    14461 taccagttag agcttagtca aaaagatgcc aatatgcgag ccttgcaggc gcaaatcaat
    14521 cctcatttta tgtataatac gctggagttc ttgcgcatgt atgcagttat gcagagtcaa
    14581 gatgagttgg cagatatcat ttatgaattc agtagtctct tgcgtaacaa tatttccgac
    14641 gaaagagaga ccctcctcaa acaggaatta gaattttgcc gtaaatacag ctatctctgc
    14701 atggttcgct atcccaagtc cattgcctat ggtttcaaga tagatccaga gttagagaat
    14761 atgaagattc ccaagtttac cttgcaaccg ctggtagaaa actatttcgc gcatggtgtt
    14821 gaccacaggc ggacagataa tgtgattagc atcaaggctc ttaaacagga tggttttgtg
    14881 gaaattttgg tggtcgataa tggtagagga atgtcggctg aaaagttggc aaatatccga
    14941 gaaaaattaa gtcagaaata ttttgaacac caagccagct acagtgatca aaggcagtct
    15001 atcggaatta tcaatgtaca cgagcgtttt gtgctctatt ttggagaccg ctatgccatt
    15061 acgatagagt ctgcagagca agccggtgtt cagtatcgta ttacaattca agatgagtag
    15121 aaagggagaa aatgtataaa gtattattag tagatgatga gtacatggtg acagaaggtc
    15181 tgaagcgttt gattcccttt gataagtggg atatggaggt cgtcgcaaca gccagtcatg
    15241 ccgatgaagc tctagaatat gttcaggaaa atcctgtcga tgtcatcatt tccgatgtca
    15301 atatgccaga caaaacaggg cttgatatga ttcgggagat gaaagagatc ttaccagatg
    15361 ctgcctatat cctgctctca ggttatcagg agtttgatta tgtaaaaaga gcaatgaacc
    15421 ttagtgtggt ggactatttg gtcaagcctg ttgataaggt agagctggga aatctgctgg
    15481 agaagattgc aggtcagctc ggcgagagag ggaagaaaag tcagactctt agtcaagaat
    15541 tagacgaggc tggatttgtt agttatttag gggataagga gaattggtgg ataggtctat
    15601 ccaaggaaaa acaaggttcc ttcaccattc cctactatgt cttgggccaa gactggcaga
    15661 ttttcatttc tgaccaaccc ctagatggtt tagtcgttac accttttgaa gctccttatc
    15721 aagaacactt tgaacgctgg aagctgaatg ctgagaaaac cctcttttac ggttctgtaa
    15781 atttgcagca gtctgagagt ctctttgcct attacgaacc gatttatagg gttatcattc
    15841 agggaaatct caatcaaatc gtagaagagt taaatctctt ggagaaggta gttcttgaaa
    15901 atacgccgcg tgttccgatt actaaacagc tttttattca gtttgtcatg gatgttttcc
    15961 atttatttga acatctcaaa gctgatgacc tgacagacat cgtcaaaacc attcatgcta
    16021 ttcaatcctt cgatgaattg gttccttata tcaaggaaac tctgagcagc tttttcggtc
    16081 aataccgtat gaatgaaaat gtggccagtg tgctggaagt cattggtcgt gattaccaaa
    16141 aagagctttc cctcaaggat atcagtaagg ctctctttat caatcctgtc tatctagggc
    16201 agttgattaa gcgtgaaacc gattcgactt ttgcagagtt actaaacaaa caacgtatta
    16261 aggctgccca acaacttttg ctttcaacta gtgacagcat cgaagatatt tgttatgctg
    16321 ttggttacag taaccttgga tatttctata aagttttccg aaaattgtgc ggaaaatcgc
    16381 caaaagccta ccgaaaacag gtagaaacta tactataaga tttgtattcc tttacaaaat
    16441 gtgctataat ataaatatta ttattaggag gttctatcat gaaaaagaaa ccaatttatc
    16501 tatgggtctt gctaatcttg tctgccctta tttcagttcc gtctctgttt ggaattgtga
    16561 gtcccttgcc tagtaaagaa gcccttcgtg ctgctcagaa acaagttgca ggggtcaatg
    16621 ctcagcaatt agaagaccag cttaattata cctatagagt agcagaagca tctcattcta
    16681 tttttaatgt tgctttgatt gtgctatcta ctattttagt ggtcgtagcg attgtcttcc
    16741 ttgttcgtaa aaatttgcaa tatgcaaact atacttacgt tggctatgtt ttgttagcta
    16801 ttattggttc gatttatggc tatgttggtt tacaagacgc tgtgcagttg gttcaagatg
    16861 agagcatgcg tttgacagtg agtattggtt caaaagctgt tagcattttc tatatcgtca
    16921 tcaatgttct cttcctagcc cttgtcttct ataagatgtg gcgacaacag aaagccttgg
    16981 cagaagaaga ggaaacagaa gagcttacct aagtattgac aaaaaagaac tatcaagata
    17041 caatcttggt agttgttttt tgattataga taaaatcatg gaggtacata tgaagacaat
    17101 ttctttagtt tatattagtt tgagtggcaa cactgaaagt tttgtgacgc gcttgaaaga
    17161 ctatctcttg tcccagtaca aagggattga ggttcaaaag attcatatca aggatttggt
    17221 caaggaaggc aaaaatttct atgaaatgga ccatccctat gtcgcttttt tgccgaccta
    17281 tctcgaaggt gggaatggcg tggataacgg agatgttgag attttgacga caccggtggg
    17341 agattttatt gcctatggta acaatgctag taagtgtttt ggtgtggttg ggtcaggaaa
    17401 tcgtaacttt aataaccaat actgcctaac agccaagcaa tacagtcaac gctttggctt
    17461 ccctgtattg gctgactttg aaatgcgagg catgctggaa gatatcaaac atgtcgcagc
    17521 tattatcgca gatttgtatg agttggaaaa ggagaattaa tactcaatga aaatcaaaga
    17581 gcaaactagg aagctagtcg caggttgctc aaagcacagc tttgaggttg cagatagagc
    17641 tgacgtggtt tgaagagatt ctcgaatagt ataaagttct tataagatgt ggttgaagtt
    17701 gttcaactgt tttttgagta taaacagtct ttaagaacgt aaaaaagcat aagttcaggt
    17761 cttcaaaacc ttgttcttat gctttttatc atagaaatat ttgctgaatt ttctcttgaa
    17821 atgaaacctt atcttcatct cgcgcttgtc ccttaccctg cttttccgat tgcgagtgcg
    17881 tagataaaga agatggcgaa gccaaagagg aaaatcaatc ccgcaatggc aaggtgtttg
    17941 agccaagaag gaagattttt gttttcacgt gttaccaagg cgtaattcaa aagagcaaag
    18001 aaaggtgttg tcaggaaaga gccaatcatg gcaaagcgga gcatggttga aacctgacca
    18061 gcgaagaact tgataatgat gataccgatg atagcagtga tggtcatcca gatgttcaaa
    18121 gatttacgat tgtcctcttt ttgactgatt agcagtcgga gagattcctg attaacgcga
    18181 gaatagccat cgataacagt tataactgtt ccaaagatac agaggaaggc aataaaagta
    18241 atcaagtaac gggaccattc gccaagaaca gaggcataca tgcccacgaa ttgagagatg
    18301 tatttggctg aagcagcttc aaccgcctgc cctgtaggat actgaatcag tgctcccagt
    18361 gccacaaaga agacggctag gatagctgtt ccaatataac cagtgttaaa gtcaaacaga
    18421 gcgtcttctg tgttaaagtt gacggtcttt ctcttttcag ctgaccaaag tgaattgata
    18481 gctgaaattt caataggagc cggcatccat cctaggaggg agacgatgaa gggcagagct
    18541 gccatttgcc aaggtgtctt ctcgacaaaa tcagaactgt attctggatg cttgaccgcc
    18601 gctatgataa ctgcaagaac agtcgcaatg gttaaggcag acataatcca tttgaccatg
    18661 ccgtctaaaa gtttgtagcc tccaaagagt agcatagccc aaatgattgc aacgagaatg
    18721 agggaccact gagtaatgct aagtccaatc attgggaagg cactggcgat gatagctgag
    18781 cacagaatgg caacaccagc cgtgttgacc atagccgaaa agacattgag gataaagaaa
    18841 atccagagat agagttttcc tttttcggca taaccttcaa ccaaagtctt tccagtatca
    18901 gctgtgtatt cagcaccaaa acggaaaaat ggatatttaa agacattggc taagatgacc
    18961 aagagaagta gagaccaacc gtaagaaccg ccagcttgag ttgaggatac aatgtgggaa
    19021 cctccaacag cggcagttgc cattaggatt ccaggtccca ttgcttttag cttgcttgcc
    19081 caggttgatt gatttaagga aatagcttgc gacatgataa atactccttt ttgaattttc
    19141 agaataatct gtatatgtaa tctatattct acaaaaaatt ttggaaaaat gcaagaatat
    19201 tttgaaaaaa gatagaaaat ttacaaagaa aatctgaaat aactgttatg atatagcaga
    19261 ttgaaactag aatagtacac ctttgcttct aaaacattgt tagaaatcga tttgactgtc
    19321 ctgatcgatt tatcctgttc ttatttcatt tcactatagt aaggtgcagc aggataaaga
    19381 aaaaccgaga agtttctttc tcggatttgc ttattatgag gtgcctattt tctatgctcc
    19441 aagagttgat tgatgtgatc tactttttta gcctctcttt tatagagaat agcccagatg
    19501 atgagataga caatcgcaaa ctcgataatg agctggaggt agaaaatcca gtggaagggg
    19561 aaccaaccag caagagttgc tagtgggaca aagccagcca gcataaggaa gaaatgagtc
    19621 agagtggcac gaagcatgct ccagtcacgg ctgaataagc agttgccaaa gttgaagagc
    19681 ataccgatgg ctgcccagat aagtgtgcag tagagcaaga ccagggcacc gtgaacctga
    19741 tgctgatcca tcacttggcc gatgagagag tagggattta gtggtgcgta ggtatttggt
    19801 gcataaatga gtgaaaagag gatggagagg atgaggccga taagaacacc ggcagctgca
    19861 tcgtgaaata cttgtttttt catagttcta atttctcctt gatggttttt agataacggc
    19921 gtgaagagta ggtgaagctt tcgtttttca agaaaatttc taccagaccg tttggcgtga
    19981 gcttgaggtg agagatggaa tcgatattga tgatttctga ttgggaaatt tggataaaat
    20041 tgcttggcaa gagtttaaga acctgataga gtcgcaaatc aatgctgtag gtctgactcg
    20101 tggtttctgc tagaaccttc cgattctcga tatagaagcg ctgaatcttg ccaatctcaa
    20161 ctagatagac ctgatcatcg atttttcctt tgattttttc tctttggtcc agattttctg
    20221 cgaactcgat gactttctgg actttttcgg tttcttgagg tgcttggaca atcagctttt
    20281 cctcctcgta agtctcacta atctgtagtt ctactttcat aaatttctct ccttgttttt
    20341 catacaaaat taatctcact tcttgtacac ctttattaat actcttcaaa aatctcttca
    20401 aaccacgtca gcatcgtctt gccgtaggat agttgttgac tttgtcaatt ttatctacaa
    20461 cctcaaaaca gtgttttgag ctgtctgcgc ctagctttct agtttgctct ttgattttta
    20521 ttgagtatac cactatttta ctccctctgg caaggtactt tgtctatgtg gagggattgg
    20581 gctcctatgt ggtggagctt ttctgttctt tctgaaatat ggtataatag cactaatcaa
    20641 tttctaggaa aatagataca gaaaggggct gaaagatgtc tcatattatt gaattgccag
    20701 agatgctggc aaaccaaatc gcggctggag aggtcattga acgtcctgcc agtgtggtca
    20761 aagagttggt agaaaatgcc attgacgcgg gctctagtca gattatcatt gagattgagg
    20821 aagctggtct caagaaggtt caaatcacag ataacggtta tggaatttcc cacgatgagg
    20881 tggagttggc cctgcgtcgc catgcgacca gtaagataaa aaatcaagca gatctctttc
    20941 ggattcggac gcttggtttt cgtggtgaag ccttgccttc tattgcgtct gttagtgtct
    21001 tgactctgtt aacggcggtg gatggtgcta gtcatggaac caagttagtc gcgcgtgggg
    21061 gtgaagttga ggaagtcatc ccagcgacta gtcctgtggg aaccaaggtt tgtgtggagg
    21121 atctcttttt caacacgcct gcccgtctca agtatatgaa gagccagcaa gcggagttgt
    21181 ctcatatcat tgatattgtc aaccgtctgg gcttggccca tcctgagatt tcttttagct
    21241 tgattagtga tggcaaggaa atgacgcgga cagcagggac tggtcaattg cgccaagcaa
    21301 tcgcagggat ttacggtttg gtcagtgcca agaagatgat tgctattgaa aactctgact
    21361 tagatttcga aatttctggc tttgtgtcct tgcctgagtt gactcgggct aaccgcaatt
    21421 atatcagcct cttcatcaat ggccgttata tcaagaactt cctgctcaat cgtgctattt
    21481 tggatggttt cggaagcaag cttatggttg gacgttttcc actggctgtc attcacatcc
    21541 atatcgaccc ttatctagcg gatgtcaatg tgcatccaac taagcaagag gtgcggattt
    21601 ccaaggaaaa agaactgatg actctggttt cagaagctat tgcaaatagt ctcaaggaac
    21661 aaaccttgat tccagatgcc ttggaaaatc ttgccaaatc gaccgtgcgc aatcgtgaga
    21721 aggtggagca aactattctc ccactcaaag aaaatacgct ctactatgag aaaactgagc
    21781 cgtcaagacc tagtcaaact gaagtagctg attatcaggt agaattgact gatgaagggc
    21841 aggatttgac cctgtttgcc aaggaaacct tggaccgatt gaccaagcca gcaaaactgc
    21901 attttgcaga gagaaagcct gctaactacg accagctaga ccatccagag ttagatcttg
    21961 ctagcatcga taaggcttat gacaaactgg agcgagaaga agcatccagc ttcccagagt
    22021 tggagttttt cggacaaatg cacgggactt atctctttgc ccaagggcga gatggacttt
    22081 acatcataga tcagcacgct gctcaggaac gggtcaagta cgaggagtac cgtgaaagca
    22141 ttggcaatgt tgaccaaagc cagcagcaac tcctagtgcc ctatatcttt gaatttcctg
    22201 cggatgatgc cctgcgtctc aaggaaagaa tgcctctctt agaggaagtg ggcgtctttc
    22261 tagcagagta cggagaaaat caatttattc tacgtgaaca tcctatttgg atggcagaag
    22321 aagagattga atcaggcatc tatgagatgt gcgacatgct ccttttgacc aaggaagttt
    22381 ctatcaagaa ataccgagca gagctggcta tcatgatgtc ttgcaagcga tctatcaagg
    22441 ccaatcatcg tattgatgat cattcagcta gacaactcct ctatcagctt tctcaatgtg
    22501 acaatcccta taactgtcct cacggacgtc ctgttttggt gcattttacc aagtcggata
    22561 tggaaaagat gttccgacgt attcaggaaa atcacaccag tctccgtgag ttggggaaat
    22621 attaaaagta taaaaaagtc tgggaaaaat tttcaaaatc aaaaaaacgc ataaaatcag
    22681 gtgttcaaaa accttgattt tatgcgtttt atcatggaaa tagttacttc attttttcct
    22741 aattcttttc gaaactcttt ttaaaccacg tcagttttat cagtaatctc aaaacagtgt
    22801 tttgagctaa ttttgccagt tttgtctgta acatcgaagt tgtgttttac cactctgcga
    22861 ctggtttcct agtttgctct atgattttca cagagtatta aattgcgatt ttgccaagtt
    22921 tctttattcg tctaaaagta gagtctgttc tatgcgtcta atgtacgaat caggttgacc
    22981 atttcaatag ctccttgtgc acactcagaa cccttatttc ctgctttagt accagctcgt
    23041 tctatggctt gttcaattgt atctgtcgtt agcacaccaa acataacagg aatttcgcta
    23101 tttaaactga tttgggcgat tcccttagat acctcgctac atacataatc ataatgactt
    23161 gtattccctc taatgacagc tcccaagcag ataattgcat catatttttt actttttgcc
    23221 atttttgatg caatcagtgg tatttcaaaa gctcctggaa cccaggctac ctctatatct
    23281 ttctcgttta cattctctct tttgagatta tctagtgctc cagataataa ttttgaagtt
    23341 ataaattcat taaatctcgc tacaacaata cctattttaa tattgtttgc tactaaatta
    23401 ccttcataag tgttcattta tttttcctcc atatttaaaa tgtgacccat tcgatttttc
    23461 tttgtttcta aataaaaact atcgtaagga ttggcttcta tttcgattga tattctactg
    23521 gaaatggtaa ttccatattt ttctaactgt tcaaccttgt caggattatt tgtcagtaaa
    23581 tgaagtgact gaagtcccag atctttaagc atttgtgctc caatatgata ttctcttaaa
    23641 tcaccttcaa agcctaatgc aagattggca tcaagcgtat ccatgccttg atcttgtaaa
    23701 tgataggctt ttaatttatt gataagtcca attcctcgtc cctcctgtcg caagtaaagt
    23761 aagacacccg aaccattctc aacaatcatt ttcatagctt tatcgaattg ctgtccacaa
    23821 tcgcaacgta aggagcctaa aacatcccct gttaaacatt cggagtggac ccgacataat
    23881 acattggctt catcctctat gtttcccata ataagagcaa gatgatgttc cccatttagt
    23941 ttatctatat agctaattgc tttgaaatta ccgtatctag taggcatatt gacagttgaa
    24001 actcgttcta ccagctgatc atatactttt ctatattctt gtaattcttt gatggtaatt
    24061 agtggaatgt tgtgtttctt cgagaactga attaaatcat ctgttctcat cattttgcca
    24121 tcatgattca ttatttcaca acataggcca cactctttta gtccagctaa ttttaataaa
    24181 tcaacagttg cttctgtgtg tccacttctt tctagaacac cacctttttt tgcaattaaa
    24241 ggaaacatgt gtcctggcct gcgaaaatca gagggtgtta tatcttcagc tacacacata
    24301 cgtgcggtca gtcctctttc ctcggcagaa atacctgtgg tcgtttcttt ataatcaatt
    24361 gaaactgtaa aagcagtctt atgattatct gtattgtttt caaccatagg tgaaagcatt
    24421 aattgattag ctaaactttc gctcataggc atacaaatta atcctttggc ataagtagcc
    24481 ataaaattaa cattttctgt tgtagctgct tgtgcagaac aaattaagtc tccttcattt
    24541 tctctatcct tgtcgtctat aacaagaaca agtcgtccct tctgcaatgc ttctaatgct
    24601 tcttgtattt ttcgatattc cattgactga ttatcctttc tgctaaaatc cattttgata
    24661 taatagttcc ttagatattt ctgattttgg agagttatcc atcagttttt gcacatattt
    24721 acctaagata tcattttcaa gatttactgt actcccgact tgtttactct taagaatggt
    24781 ttgttccaag gtatgaggga taacagatac tgaaaagttt actttggaga ctttagcgac
    24841 agtcagacta atgccgtcaa ttgtaataga tcctttttca actattaaat ctaaaatttc
    24901 tttttgtgtg ttgatttgat accatacagc attatcatct ttttttattg acgagatttt
    24961 tcctgtacca tcaatgtgtc ctgtaacgac gtgaccccca agtcgaccgt tgatagataa
    25021 ggctctttct agattcacct cacttccatg ttttaataga gtaagagctg ttcgactcca
    25081 tgtttcattc attacatcaa ctgtaaagga ttgatgattg aaatgagtaa ctgtaagaca
    25141 gataccattt actgctatac tatcgcctaa atggatatcc gttaatattt ttgaggcttt
    25201 aattgatagt ttacaattac gagagtcttt ctgtattctt tcaacttttc cgatttcttc
    25261 aattattcct gtgaacatgg ataaatcact tcactttcta tgagatagtc atttcctatt
    25321 tgagaaaaag cataaggttt caatctaata gcgtcatttg gcaaagaaat gccttcacct
    25381 ccgacaggaa acttggcact gcctccaaaa atttttggtg caatatatat tttcagctca
    25441 tcaacaattt gttgttccaa agcactccaa ttcattagac tgcccccttc tagaactagg
    25501 ctatcaatct gcatgtttcc tagatgttgc attaaactcg ataagtctat atgattgcct
    25561 tttttcttta tggaaagtat ttcacagcca tgattttgat atagcttcat tttatttttg
    25621 tcttcagagg aagtggcaat gtaagtttta atatcatttg ctgtttttac gattttagag
    25681 gtaagaggag ttcgtaaatg tgtatcgcat atgatacgga taggattttt cccttcctcc
    25741 aatctacatg tcagcaaagg atcgtcttga ataacagtat tgactcccac cataattgca
    25801 ctaacatggt gtcgtaactg atgcacatgc tttcttgctt cttcttcagt aatccatttg
    25861 gattgatttg ttttagtggc tatttttcca tccattgaca ttgcatattt cataaaaaca
    25921 tagggtacat gctgggtaat atactttcta aaacttttta ttaagttaag acactcattt
    25981 tctaaaattc caacagtaac ttgaagatta ttttcctcaa gtatctttac tccttttcca
    26041 gatacaatag gattacagtc taggcttcca atgactactc ttgtaatacc actatcgatt
    26101 atagcatcta tacagggagg tgttttcccg aagtgacaac agggttcaag tgttacataa
    26161 agcgtcgctc cgacagggga ttctctacag tttttaagag catttctctc agcatgtggg
    26221 ccaccaaaaa actcatgata accttgtccg atgatgtgat tatcttttac aataactgcg
    26281 ccgaccatag gattggggtt gacgtaacca gccccttttt gtgccagttt tattgctaat
    26341 ttcatatatt ttgaatcgct catctcacta cctccaaaaa atataccttg aataggggac
    26401 tactcaaggc atacaaaaga aaacttatgc gattaacaaa aatgctctga aatgacaagt
    26461 aatcatttca gagcacgcaa aaagcacaaa tatactttta tcttctttca tccagactat
    26521 actgtcggct ttggaatttc accaaatcat gcctttcggc tcgtgggcta taccaccggt
    26581 agggaattgc accctgccct gaagatagtt attcaattac agatgattat agtacttaat
    26641 tttgaatatg tcaacagata aatatcgatt gtttttgata tactgtattt gtgataatcg
    26701 attctcgctc ctcggataaa gaaaatatga tatactagat aaacgaaata agagagaagg
    26761 aacactatgt acgcatattt aaaaggaatc attaccaaaa ttactgccaa atacattgtt
    26821 cttgaaacca atggtattgg ttatatcctg catgtggcca atccttatgc ctattcaggt
    26881 caggttaatc aggaggatca gatttatgtg catcaggttg tgcgtgagga cgcccatttg
    26941 ctttatggat ttcgctcaga ggatgagaaa aagctctttc ttagtctgat ttcggtctct
    27001 gggattggtc ctgtatcagc tcttgctatt atcgctgctg atgacaatgc tggcttggtt
    27061 caagccattg aaaccaagaa catcacctac ttgaccaagt tccctaaaat tggcaagaaa
    27121 acagcccagc agatggtgct ggacttggaa ggcaaggtag tagttgcagg agatgacctt
    27181 cctgccaagg tcgcagtgca agcaagtgct gaaaaccaag aattggaaga agctatggaa
    27241 gccatgttgg ctctgggcta caaggcaaca gagctcaaga aaatcaagaa attctttgaa
    27301 ggaacgacag atacagctga gaactatatc aagtcggccc ttaaaatgtt ggtcaaatag
    27361 gagcagagaa tgacaaaacg ttgttcgtgg gtcaagatga ccaacccgct ctacatcgcc
    27421 tatcatgatg aggagtgggg tcagcccctc catgatgacc aagcattgtt tgagttgttg
    27481 tgtatggaaa cctatcaggc aggcctgtct tgggaaacgg tactcaacaa acgccaagct
    27541 ttccgagaag cctttcatag ctatcaaatt cactcagtcg cagagatgac tgacactgaa
    27601 ttggaagcca tactggagaa tccagctatc attcgaaata gagccaagat ttttgctaca
    27661 cgcgctaacg cccaagcctt tctacagtta caggcagagt acggctcttt tgatgcctat
    27721 ctttggtctt ttgttgaggg gaaaactgtc gttaacgatg ttcctgatta tcgccaagcc
    27781 ccagctaaaa cacccttatc tgagaaatta gccaaagatc tcaaaaaacg aggcttcaag
    27841 ttcacaggcc cagtcgccgt attgtctttt ctacaggctg cagggctagt tgatgaccac
    27901 gagaatgatt gtgagtggag aggtcttaaa tgatgtctaa caaaaataag ggaattctga
    27961 tttttgcgat tctctataca gtcctctttg tgtttgatgg cgttaaattg ctggcttctt
    28021 taatgccatc tgtcattgca aattatcttg tttatgtagt tttagctcta tatggctcct
    28081 tcttgttcaa ggatagattg atccaacaat ggaaggagat tagaaagact aaaagaaaat
    28141 tcttctttgg cgtcttaaca ggatggctct ttctcattct gatgactgtt gtctttgaat
    28201 ttgtatcaga gatgttgaag cagtttgtgg gactagatgg acaaggtcta aatcagtcta
    28261 atattcaaag tacctttcaa gaacaaccac tactgatagc tgtttttgct tgtgtcattg
    28321 gacctctggt agaagaatta tttttccgtc aggtcttatt gcattacttg caggaacggt
    28381 tgccaggttt actaagcatt attctggtag gacttgtttt tgctctgact catatgcaca
    28441 gtttggctct atcagagtgg attggtgcag ttggttactt aggtggaggc cttgcctttt
    28501 ctattattta tgtgaaagaa aaagagaata tctactatcc cctacttgtt cacatgttaa
    28561 gcaacagcct ctccttaatc attttagcta tcagtatagt aaaatgaaat aagaacagga
    28621 caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta
    28681 ttctagtttc aatttgctgt aatatgtgat gaaaatacca gtaatgatac cgagaaaaaa
    28741 gctgagaaac ttttcccagc tttatttgtt atagtcaaag cgaatgactt gttcctgtgc
    28801 atctacatga gcatggaccc caaagggtac aattgctctt ggagttgcgt ggccgacatt
    28861 cagattatag acaatcggga tattgctgtc aatgatatcc aatagtgcct ctttatagtc
    28921 gtcatggaaa gtttcatcca taggttttcc gaccaagagt ccattgatga ccgcgaatat
    28981 gccagtgtcc tttaaagtta gcaacatctt tttgaagtct tctggcttag gcttttcttc
    29041 gcttgtttcg agcaagagga ttttcccttc ccagtctgac aagtcaggga aaagtttgta
    29101 tttttggcag agttccgtgc tatctgcgta tcgagagttg tcaaagatat cgtagaggga
    29161 ttcgaggcaa ccaccgagga tttttccctc gaactgagca cttccttgca acaagtcaaa
    29221 acctgtattt gtatgactga cacgaggtgt tcccagggcc gtgggactaa aatcagttcg
    29281 ttcctcatac caaacgtcac tagggcggat ttctgaaatt cttcccgtct taatcaattc
    29341 tttaaagtag tgaaggctat aggctagcat ttctttgtct aattcacaaa tgtctgctaa
    29401 aaaggattga ccataaaaag tcttgattcc taatttatgc aacatgaggt ggttcatggt
    29461 tgtatccgag aagccaagaa aaattttttg cttgataacc ttttggagtt ggtcattttc
    29521 aaaaagataa ggtagcaagc gataggtatc gtctccaccg atggcacata ggatcatgtc
    29581 gatgctatca tcagaaaagg catgaatcaa atcctctgca cgagcttcag gatggtcctt
    29641 gataaagtct aatcctttta acgaatggga caaaaagatg ggattgagtc ccagatcctt
    29701 gagacgttgg atacccaagt ccacttcgtg tttgacaaaa tcctctccga taatgccact
    29761 agataaacta acaataccaa tagtagaaac catatctcat cctcctagaa atagattgag
    29821 cctattttat cacaaaatat aagagaaagc tatgtgggat ttcagaagaa tacttttaat
    29881 actcttcgaa aatctcttca aaccacgtca gttttatctg caacctcaaa gctgtgcttt
    29941 gagcaacctg cagctagctt cctagtttgc tctttgattt tcattgaata taactcaaaa
    30001 aagtaagtga aaaagcaacc gcacctgcag ttgcttttat cgttttctta ttcttgatag
    30061 cgtgttggtc ctgcacttgc actacggata ttcaagcgtt tcttgagata gaagcgaagg
    30121 gctaggaggg ctgctccaat aatagctagt ggcaatggat ccagtactgg gttaaggcta
    30181 gctggtagga agcttgttgc aaagaagaca agcaaccaaa ggaacataga agctaggata
    30241 actagtacag atttccagaa aggtggacgt tgactgcgat ccatatctga tccatagtat
    30301 tggtaaacaa agtagtacat caagtagaag gcaaatccac caaccagtcc aactaataga
    30361 agagtaatca atccatagcc gaaagcttgg tctgccgcaa agaaggttgt gagggcgctg
    30421 acaagggcaa agaggctagt gatgaaaaga gctgagtcca taatcatcag ttttgggtca
    30481 tcattttctt ttggatgctc tttttcgtac tgctctttga cagtgaagct atgagcccaa
    30541 tgagttggtg cgccgtatag ggaacgggca gttgtacctt tagattgctc ctcaaggatt
    30601 tggggaatga cttcctcaaa aatagtctgg atttcagcgt ctgttttccc atctttgatg
    30661 aattgttggg tagcaatgtg gacaaactct tggtttttct tagttaattt ttgtagatca
    30721 atttgagaca taggaactcc tcttagaacc attttttatg gatgagatag agagtgagcg
    30781 agacactcat agcaaaggcg ataaagacga ttaaccagaa ggcatttggc tctccgttta
    30841 gggggatttc attatcctta aagttcatcc cgtaggcaga aaagaccatg gttgggatgg
    30901 acatgacgat ggtcacaagg gccaaggttt tcatgatgtt gttctggttg ttagaaatga
    30961 tagaggcaaa ggtctctgtc atagaatgca agacgtttcc ataaatatct gccatctcga
    31021 tggcctgttg ggtttcaatc agggtgtctt caagcaggtc ttcgtcctca aggtatttct
    31081 tgatattgct ggttgaactg gtcaatttct taatcacgcg ctcatttgtt ttgagggagg
    31141 ccttgaaata gacgatagtt ttttccaatt ccatgagctc aatcaattct tcattacgag
    31201 ttgattgatg cagttgactt tcgatttgtt cactcttgcg gtcgattgaa cgaagggctg
    31261 ttaggtaaag ctctgcattg cgataaagaa tttgaaagat aaaacgtgaa cgcatgaagg
    31321 tatagaaatt acgcaatcga cggttgataa agacatcaag gacaggtagt ggttccaaac
    31381 acgtagtgat aatggtttcc tcagtgatga taataccaag cgggatggtt acgtagtagg
    31441 tgcggttatt tctttcctcc gtgaccggca cgtctacgat aatcagggta tactcgtctt
    31501 caatggtaat acgagacatt tcttccgcat cgagcggtgc tcgaaggtcg gcaatatcaa
    31561 tatcgaaggt gttggcgatt tcgagtgatt cattttgagt cggattgacg agattgatcc
    31621 aagtacccgg ttcaagcgta tcgatctctt taaattcagt tgttgtagag agaaaaactt
    31681 gtttcatatc ccttatcctt tctcattttt cagatttttt cacactgtac tattatacta
    31741 caaaatcggc cttttgggta atagaatctc actttttttg gtataatggt aagcaataat
    31801 ggactagaaa gaacaaagat gcaagataaa attgtcattc atggggcgcg tgcccataat
    31861 ttaaaaaata ttgatgtgga gattccgcga gacaagttgg ttgtcgtgac tggcttgtca
    31921 ggttcaggga agtccagtct ggcttttgat actctctatg cggagggaca acgtcgctat
    31981 gtagagagtt tgtccgccta cgctcgtcag ttcttgggaa atatggaaaa accagatgta
    32041 gatgccattg atggtctcag cccagctatt tccatcgacc agaaaacgac tagtaaaaat
    32101 cctcgctcga cggtgggaac gacgactgaa atcaatgact atctgcgtct cctctacgca
    32161 cgtgtgggga cgccttactg tatcaacgga catggagcta tcaatgcttc ttctgtggag
    32221 caaatcgttg ataaggtttt ggagttacct gaacgccagc gcttgcagat cttggctcct
    32281 gtcatccgca agaaaaaagg ccaacataag agtgttatcg agaaggttca gaaagacggg
    32341 tatgttcgtg tccgtgtgga tggggaagtc tatgatgtga ccgaagtgcc agagttgtct
    32401 aagagcaagc aacacaatat cgatgtcgtg gttgaccgta ttgttatcaa ggagggcatt
    32461 cgtagtcgtc tctttgattc cattgaggct gcccttcgta ttgcagaagg ttatgtcatt
    32521 atcgacacca tggacgactc ggagttgctc ttctctgagc attatgcctg tccagtttgt
    32581 ggatttactg tcccagagtt agaacctcgt ctcttctctt tcaatgctcc ctttggctct
    32641 tgtagtgagt gtgacggctt ggggattaag ctggaggtgg atactgattt ggtagtgcca
    32701 gatgccagca aaaccttaca tgagggagcg ctggcacctt ggaatcctat ctcatccaac
    32761 tactatccaa acatgttaga gcaggccatg aaagtctttg gagtggctat ggataagcct
    32821 tttgaggacc tgtcagaaga agataagaac ttgattctct acggctcaga tggtaaggaa
    32881 ttccatttcc attatgaaaa tgaatttggt ggtgtgcgcg atatcgacat tccgtttgag
    32941 ggagttatca ataatatcaa acgtcgttac catgaaacca atagcgatta cactcgcact
    33001 cagatgcgtc tctacatgaa tgagctgacc tgcggaacct gtcaaggcta tcgtctcaat
    33061 gaccaggcct tgtctgtccg tgtgggcggc cagcaagggc cacatattgg agaaatctca
    33121 gacctgtcta tcgctgacca cttggacttg gtgagccagt taactttgtc tgaaaatgaa
    33181 gccatcattg ctcgtcccat tctcaaggaa atcaaggatc gtttgacctt ccttaataat
    33241 gtgggtctta actatctaac cctgtcacgt tcagcaggaa ccctttcagg tggggaaagt
    33301 cagcgcattc gtttggcaac ccagattggt tccaacctat caggtgtcct ctatatccta
    33361 gacgagccgt caatcggtct tcaccagagg gacaatgacc gcctgattgc cagtctgaaa
    33421 aagatgcgtg acttgggcaa tactcttatc gtggtggaac acgacgaaga taccatgcgt
    33481 gaagctgatt atctgattga cgttggtcct ggtgccggtg tttttggtgg tgagattgtt
    33541 gcagcaggta cacctaagca agtggctcgc aacagcaagt ctatcacagg tcagtacttg
    33601 tcaggcaaac gtgtcatccc agtaccagaa gagcgccgtg tcggaaatgg tcgttttatt
    33661 gaagtgacag gagcgcgtga gaacaacttg caaaatgtca cggctcgctt tccactagga
    33721 aaatttatcg cagtgacagg tgtgtcgggt tcagggaaat cgactctaat caacagcatt
    33781 ctcaaaaaag ccattgccca gaagctcaac cgtaattcag acaaacctgg taagtttaag
    33841 actattacag ggattgagca tgtcgaccgt ttgattgata ttgaccagag ccctatcgga
    33901 cggacgccga ggtctaaccc agctacctat acaggagttt ttgacgatat acgtgacctt
    33961 tttgctcaga caaatgaagc caagattcga ggctacaaga aggggcgctt cagtttcaac
    34021 gtcaagggag gtcgctgtga agcttgctca ggtgacggga ttatcaagat tgagatgcac
    34081 ttcttgccag atgtttatgt ggcttgtgaa gtttgccacg gaacccgcta taacagtgaa
    34141 accctagaag ttcactacaa ggaaaagaat atttcgcagg tcttggatat gacggtcaac
    34201 gatgcggtag aatttttcca acacattccg aaaattcaac gcaaactcca gaccatcaag
    34261 gatgtaggtc taggctatgt gaccttggga cagccagcta ccaccctttc tgggggagaa
    34321 gcccaacgta tgaagttagc tagcgaactc cacaaacgct cgacaggaaa atctttctac
    34381 attctggatg agccgacgac agggcttcat acagaggaca ttgctcgcct gctcaaggtt
    34441 ttagctcgct ttgtagacgc cggcaataca gtcctcgtca tcgagcacaa tctggatgtt
    34501 atcaagacgg cagaccatat cattgacttg ggacctgagg gcggtgtcgg tggtggaacc
    34561 atcatcgtaa caggaactcc agaagaagta gctgccaacg aagccagcta cacaggacac
    34621 tatttgaaag gaaagttaca tcatgaataa acgcgtacaa gcatttctag ctaaaatgca
    34681 agaaaaagaa ctagatggta tcatcatcaa caatcttaaa aacgtctatt atttgactgg
    34741 tttttggggc tcaaacggaa cagtctttat cagccgtgac cgtcaggtct tagtgacaga
    34801 ctctcgctat atcatcgcag ctaagcaaga aaccagtggt tttgagattg tggctgatcg
    34861 tgatgaattg gctgtcattg caggaattgt taaggacatg aacttgactc gtatcggttt
    34921 tgaagatgag atttcagtgt cttattacca ccgtatgcag gcagcttttg caggtttgaa
    34981 cttgcttcca caaactcagt ttgtggaagg tcttcgtatg attaaggatg aggcagagat
    35041 tgcagcgatt cgcaaggctt gttctatctc agaccaagct ttccgcgatg cgcttgactt
    35101 tatcaaacca ggaaaaactg aaattgagat tgccaacttc cttgatttcc gcatgcgtga
    35161 gttgggagca tctggcttat cttttgatac gatcctagct agcggtatca attcttctaa
    35221 accccatgcc catccaatgc acaaaccagt ggagttggga gaagccatca ccatggactt
    35281 cggctgtctc tatgaccact atgtcagtga tatgacccgg actatctatc tagggcatgt
    35341 tagcgatgag caggcagaga tttacaatac ggttctaaaa gctaaccaag ccttgattga
    35401 ccaagctaag gcaggcttag gtttccgtga ctttgacaaa atccctcgtg atattatcat
    35461 tgaggcaggt tatggtgact actttactca cggcattggc cacggtattg gtctggatat
    35521 ccatgaggaa ccctacttta gtcagacttc tacagaaact attaagacag gtatggcctt
    35581 gaccgatgaa ccaggtatct atatcgaagg caaatatggc gttcgtatcg aggatgatat
    35641 cctgattaca gagacaggtt gtgaattatt gaccctagct ccaaaagagt tgatagtcat
    35701 ttagttgttt gtcaagaaaa aagtacgaaa atgacgaaaa aagtcaaaaa aaattaaaaa
    35761 taggtcgcaa gtcggatgtt ttttatggta taatagacta aactgatagt aacatgtagc
    35821 gaaaggggta ggtacatgat taaaatttat acagtctcaa gttgtactag ctgtaaaaaa
    35881 gcaaaaacct ggctcaatgc ccaccagtta agttataaag aacaaaacct tggtaaagaa
    35941 ggaattacga gagaagaatt actggatatt ctaaccaaaa cagataacgg aatagccagc
    36001 atcgtttcgt ctaaaaatcg ctatgccaaa gcccttggag tggatattga agatttgagt
    36061 gtcaatgaag ttctcaatct gattatggaa acaccgagaa ttttaaagag cccaatcctt
    36121 gtagatgaaa aacgcctgca agttggctac aaggaagacg atattcgtgc cttcctacca
    36181 cgctctgtcc gtaatgtaga aaatgcagaa gcacgtttgc gtgcagctct ataaacatca
    36241 aggctgggag cacttcccag tcttattcta ttttaatttc aaaaagaaag aagaaagaaa
    36301 tgaaaaaaat agttcttgtt agtctagctt tcctttttgt cctggttggt tgcggacaga
    36361 aaaaagaaac tggaccagct acaaaaacag aaaaagatac gcttcagtcg gcattgccag
    36421 ttattgaaaa tgctgagaag aatacagttg taactaagac tttggtcttg cccaagtcag
    36481 atgatggtag ccagcagaca caaacaatta cttacaaaga caagactttt ttgagtctag
    36541 ctatccaaca aaaacgtcca gtctctgatg agttgaagac ttatattgac caacatggag
    36601 tggaggaaac tcaaaaagct cttcttgaag cggaggagaa ggataagtct atcattgaag
    36661 ctcgtaaatt ggcaggtttc aaacttgaaa caaaactatt gagcgcaacg gaacttcaaa
    36721 caacgactag ttttgatttt caagttctgg atgtcaagaa ggcttcccag ttggaacatc
    36781 tgaagaatat tggtttggaa aatcttttga aaaatgaacc aagcaaatat atttcagata
    36841 gattggcaaa tggcgcgaca gaacaataga aaatccaaat aaatagactg cctgaattgt
    36901 agaaggtaag gaattatgct ataatggtac tattctaagg aaagagggtg ttagaatggg
    36961 atttactgaa gaaacagtac gttttaaatt ggacgattcc aataaaaaag aaattagcga
    37021 aactttgaca gatgtttatg cttcgttgaa cgataagggt tacaacccaa ttaaccaaat
    37081 cgtaggttac gtattgagtg gagaccctgc ctacgttcct cgttataata atgcacgaaa
    37141 tcaaatccgt aagtatgagc gtgatgaaat cgttgaggaa ttggttcgct actacctcaa
    37201 aggacaagga gtcgatctat aacctatgag aattatggga ttggacgtcg gttcaaaaac
    37261 ggtaggggtg gcgattagcg atccgcttgg ttttacagct caagggcttg aaatcatcca
    37321 gataaatgaa gaacaaggcc aatttggttt tgaccgcgtt aaggaattgg ttgatactta
    37381 caaggtggaa cgatttgtag tgggcttgcc taaaaacatg aacaatacaa gtggaccgcg
    37441 cgtagaagct agtcaagcct acggagcaaa gctagaagag ttttttggtt taccagtaga
    37501 ctatcaggat gaacgcttga caacagtggc tgctgagcgc atgttgattg aacaagcaga
    37561 tatcagtcgc aataagcgca agaaagtcat tgataagtta gcagctcagc tgattttaca
    37621 aaattattta gatagaaaat tttaatataa aggagaggct atgtcacacg atcataacca
    37681 cgaccacgaa gaacgtgaac taatcacact agtagatgag caaggaaatg aaaccttgtt
    37741 tgaaatcctt ttgacaattg atggaaaaga agaatttggt aaaaactatg ttcttctagt
    37801 accagttaac gcagaagaag acgaagacgg acaagttgaa atccaagctt actcattcat
    37861 tgaaaatgaa gatggaacag aaggcgaatt gcaaccaatc ccagaagact cagaagacga
    37921 atggaacatg attgaagaag tcttcaacag ctttatggag gagtgataca gtctgggaga
    37981 ctgtatcagc ccaactccca gaaatgggga agagttggaa cgtccagtga acatttttac
    38041 cccatattca cattcatagt ggctagttat tagctaatca ggtaagaggt cgggacgaaa
    38101 atcctggcct tgtttttatt agtaaccata ctttaatgcg ataattgatt ggacttttgt
    38161 caaggagatg tgtatgtttg aagtagaaga atggctccat agtcggattg gtttgaattt
    38221 tcgatcaggt ttgggccgaa tgcagcaagc ggtggatttg ttaggaaatc ctgagcagtc
    38281 ttaccctatt atccacgtaa cagggactaa tgggaaagga tctaccattg cttttatgag
    38341 ggaattattt atggggcatg gcaaaaaagt tgcgaccttt acctcccctc atatcgtctc
    38401 tatcaatgac cgaatctgca ttaatgggca acctatagca gacgcagact ttatccgttt
    38461 gactgatcag gtcaaggaga tggagaaaac gcttctgcaa actcctgccc agttgtcctt
    38521 ttttgaattg ctgaccttag ttgcttttct ttattttagg gagcaagagg tggatttggt
    38581 tttattagaa gtgggaattg gtggcttact tgacacgacc aatgtggtaa ctggagagct
    38641 tgctgtcatc acctccattg ggcttgacca tcaagaaacc ttgggtgata gtctagaagc
    38701 aattgcagag cagaaagctg gtattttcaa ggctggtaag aaggcagtga ttgcgaaatt
    38761 gcctccagaa gctaggcttg tctgtcagaa aaaagccgaa tctttagctg ttaaccttta
    38821 tcaggcaggt caagattttt taatgctgaa tggtgatttt tcaagctctt tactaaatct
    38881 ttcacagctg aacataggct tagaaggagt ctatcagcag gagaatgcag ccttggcgtt
    38941 gcaaactttt cttcttttta tgggagaagg aaaggaagct gttgatgaac aggctgtaag
    39001 aaaggccttg gaacagaccc attgggctgg tcgcttggag cgtattcgcc cacagattta
    39061 cttggatggt gctcataacc tccctgcctt gactcgcttg gttgagttta tcaaagaaaa
    39121 agagcaggaa ggctatcgac ctcaaatcct ctttggatcc ttgaaacgta aggattatca
    39181 agggatgttg ggttatctga ctgaaaattt acctcaagtg gaactcaaga tgactggctt
    39241 tgactatcaa gggtctttgg acgagacaga tgtaacaggt taccatgtaa ttccctctta
    39301 ccgagaattt atcagcagtt tcgaagaaag ggcagacgct caagacttgc tgttcgttac
    39361 agggtctctc tattttatct cagaagtacg gggctacctg ctggaccgtg agcagataaa
    39421 ttgactccat tttttgaact tgttatacta ggggaattgc tggttagaga aaatttctct
    39481 aaattggtag cagaaaggaa attcatcatg aaattaaaaa gattcacact ttctcttgct
    39541 tctctagcaa gttttagtct cttagtagct tgttcacaaa gagctcaaca ggttcaacag
    39601 cctgttgctc agcagcaggt ccaacaacct gctcaacaga ataccaatac tgcaaatgca
    39661 ggaggtaacc aaaatcaagc ggctccagta caaaaccaac ctgttgctca accgaccgat
    39721 attgatggga cttatactgg tcaggatgac ggagaccgta tcactttagt ggtaactgga
    39781 acgactggta catggactga gctcgaatct gacggggatc agaaagtcaa acaggttaca
    39841 ttggattcag caaatcaacg catgattatt ggcgatgatg tcaaaattta cactgtaaac
    39901 ggtaatcaaa tcgtcgtaga tgatatggat agagacccat cggaccaaat cgttttaact
    39961 aaataagact atgcaagtag aaagggctgg atttttcagc ctttttactt ttacctagaa
    40021 aataatcata aatacttgcc ttctaccgaa tacctgcgtt atactagtat caattacttg
    40081 tttttagcat tcaaactatc aaggagggga tatgaaatat aggaaatttc agttattgat
    40141 gtccaagtat ggctttagtc tttcgattat gctacttgaa ctttgtcttg tttttggtct
    40201 ctttctttat ttaggacgca tggctcccat tttatggatt actgtcctca ttctactgag
    40261 tatcatcaca atcatttcga tagtcaaccg taatacgact cctgagaata aggtaacctg
    40321 gttgttagta gcctttgtac cagtatttgg tcccttgctc tatctgatgt ttggtgaaag
    40381 gcgattgtcc aaaaaagaaa tcaaacaact gaagaagcta ggctctatgc atttccaaga
    40441 agcaaatagc cagctactaa aagagaaatt aaaagaaagt gacaaggcag cttatggagt
    40501 catcaagtcc ttattgagta tggataccaa tgctgacatc tatgatcaaa ctgcctctac
    40561 attttttcct aacggagaag ctatgtggaa aaagatggta gaagatctta aaaaggctga
    40621 gaaatttatt ttcttggaat attacattat agaagaaggt ttgatgtgga atcgcatact
    40681 agatatacta gagcaaaagg tagctcaggg tgtagaggtt aagatgctct atgatgatat
    40741 cggctgtatg gctactttaa caggagatta tgcacatcga cttcgtcagc tgggcatcga
    40801 ggcccataaa ttcaataaag ttattcctcg tttgacagtg gcttataata acagagatca
    40861 tagaaaaata ttgattgttg atggtcagat agcctatact ggtggggtca atctggcaga
    40921 tgagtacatt aaccacgtcg agagatttgg ttattggaag gatagtggaa ttcgcttaga
    40981 cggactagca gtaaaagccc tgacacgctt atttttgacc acttggtaca ttaatcgagg
    41041 agaaattagt gattttgatc aatatcattt agaaaatcat tctatcccga gtgacggttt
    41101 aaccattcca tacggaagtg gacccaagcc aatttttcga gcgcaggtag ggaaaaaagt
    41161 ttatcagagt ttaatcaatc aagcaacgga atcggtctat attacgacac cttatttgat
    41221 tatagattat gatttaacag agacaatcaa aaatgcagct atgagagggg tcgatgttcg
    41281 aattatcacc ccttacatac cagataagaa gttcattcag ttagtcacga gaggagctta
    41341 tcccgacctt ctttctgctg gtgttcggat ttatgagtat agtccaggtt ttattcatag
    41401 taagcagatg ttggtagacg aagattttgc ggtggtgggg acaatcaatc tcgactaccg
    41461 gagcttggta caccattatg aaaatgcagt cttactctat aaaactcctt ctataaggga
    41521 aatcgcccga gattttcgaa atatatttgc agattctcag gaagtctatc ctcattctat
    41581 caaaacgagc tggtatcaaa agcttgtaaa agaaatcgcc cagctattcg cccctatctt
    41641 ataagaaatc tagaacttag gatacaaacc agacctattt ttcttgtctt ttacgaatag
    41701 aaagaaagag gaggggaatt catgctaact aaggaagaag tgaatgatat gattgagttc
    41761 aaacagacac atttacaccg ctttcgggaa attgaaacct ttgtgaaact atgcaaaaaa
    41821 tcactcaaac agccatcgca agctgacaat cctaggactt tttgatatac taagacagat
    41881 aaattgaaca ggagaaacga tatgagtgtg tatggtagag tagaagaagt tcataaggag
    41941 aatcgtgaac ctctagaata ccaaatcgaa caagaatcgc atcatcgtga atcaagtcgt
    42001 cttcctttgg tgaaaatttt actatggagt acgcttgtaa cggggataac tctaggagta
    42061 ccgctattac tcgacttaat gagtgcacaa gaagtgcagg atttttatgc aggttgggcg
    42121 cttcatcaga cagggaagat ttacagcgac tattatggaa gtcaaggttt gctttattat
    42181 ttgctgactt acgtgagtca gggcggattt ttctttgcca tctttgagtg gttagccttg
    42241 gtagcaggag gatttttcct ttttagatca gcggacacct tgacagagca aggagaccaa
    42301 gctggacatc tggtgactat tttttacatg ctagttacag gtcttgcttt tggtggaggc
    42361 tatgcgactc ttttagcgct tcctttctta ttcgcagcct ttagtttagt tgcggcttac
    42421 ctaagcaatc caagccatga taagggattt gtacggattg ggctagcttt ggcaggcgga
    42481 tttttctttg ctcccttatc atcgctcctg tttattgctg tagtgagttt aggcttgttg
    42541 gtctttaacc ttgggcatag acgctttgcg catgggtttt atcagtttct tgcagtggct
    42601 ttaggttttt cacttgtctt ttatccaact gcctactata gtgctgcaac aggaagtttt
    42661 ggggatgcga ttagtggtat tcgttatcct attgacagta ttcgctttga ttttacttct
    42721 aaaattttag agaatatgtt tttttatggc ttgttgtccc ttggtttggg atttgtggtt
    42781 tgtatctttt taggtctctt tcaatccaaa ccctttaaac tatacgtcat ttcggttcct
    42841 gcaagtcttg tggtaatttt aggtttgatt ttacttttct tttcacaaga gcctctgcac
    42901 gcttcttatt tgatggtcgt cttccctgtt ttcctacttt tattggtaac caatattaag
    42961 agtcaacaga gggggcgtag tgctagaaga agccgaagag aaacgccagt tagcctatgg
    43021 agtcgtttct tcaaaggaaa tctatatctg ctagtttttg ggtttgtcta tcttttgtct
    43081 gttccttttt tgatgaagtt tgtcctttat ccagtacctt atcaagaacg taatcgtctt
    43141 gctgatttgg taaaagagga gacaaatacg gaagatgcta tctatgcatg ggatgatact
    43201 gcgactcttt atcgtaagag tgagcgcttg tcgccatcgg cgattttgtc cccgttgcac
    43261 tatacagcaa ctgaggaaaa tcgtaataag ttacttaatg acttgaaaga aaaacaacct
    43321 aaggtgattg tggtaaatga caaggtggta gtctggtctg aagtggaaac actcttaaaa
    43381 gaaaattacc aacaagtaaa gactgattac tcagagttta aagtctataa aattaaataa
    43441 ccaaatcaat atcttgtgta tttttaaaaa ttttaggatt tttaacacaa gatattgatt
    43501 tttcttttta gagtggtata atacttttta gaaagaacat tttagaaaag agcatgcata
    43561 tgattgcact agaagaaaaa attacaattt tgccaactct cttcgtcgag aaacgagatg
    43621 ggagacgtgt tgtatttgat gtggacaaga ttgacaaggc tctccacaag gcggctgaca
    43681 aggttatgga tgtgacaccc ctggttgaaa aacgcctcaa tgatctgact gagcgaatta
    43741 ttacagaaat tcatagtcgc tttccacagg gaattaagat ttacgaaatt caaaatatcg
    43801 tagaacatga actccttgaa gccaaagaat atgcgctggc tgaggagtat attacttatc
    43861 ggacacagag ggattttgag cgctcaaaag cgacggatat caactttagt attcataaac
    43921 ttctcaacaa agaccagaca gttgtcaatg aaaatgctaa taaagacagt gatgtcttta
    43981 acactcagcg tgatttgaca gcagggattg ttgggaaatc aatcggactg caaatgcttc
    44041 ctaagcacgt agccaatgcc caccaaaagg gggatatcca ctatcacgat ttggactaca
    44101 gtccctatac ccctatgacc aactgctgtt tgattgattt taagggtatg ttggaaaatg
    44161 gttttaagat tggaaatgca gaggtagaga gtcccaagtc tatccagact gcgacagcac
    44221 agatttctca aatcattgcc aacgttgctt ctagccagta cggtggctgt tcagctgacc
    44281 gtatcgatga aattttggcg ccttatgcag agaagaacta tcaaaaacat ctcaaagatg
    44341 cagaagagtg ggtattgcct gaaaaacggg aagattacgc ttggaagaaa acgcaaaagg
    44401 acatctacga tgccatgcaa tctcttgagt atgaaatcaa tactctcttt acttcaaatg
    44461 gacaaacacc ttttacttcg ctaggttttg gtctgggaac cagtcgtttt gaacgagaaa
    44521 ttcaaaaagc tattttaaac attcgcatca agggtcttgg ttcagaacac cgtacggcta
    44581 tctttcctaa acttatcttt acgcttaaaa gaggcctcaa cttagaggaa ggaactccca
    44641 actatgacat caagcagttg gctctagagt gtgcaaccaa gcggatgtat ccagacgtct
    44701 tgtcttatga taagattgtt gatttgacag gttctttcaa ggtgcctatg ggctgccgtt
    44761 ctttccttca agggtggaag gatgaaaatg gtgtagaagt caattcaggt cgcatgaatc
    44821 tgggtgttgt gacggttaat ctgcctcgta ttgctcttga gtctgaaggt gatatgaata
    44881 agttctggga aatcttcaac gagcgaatga atatcgcaga agatgctctt gtttaccgtg
    44941 tcgaacgcac taaagaggcg acaccagcga atgctcctat tctttatcag tacggtgctt
    45001 ttggccatcg tctaggtaaa gaagaaagtg ttgaccagct ctttaagaat cgtcgtgcga
    45061 ccgtttcgct gggctatatc ggcttgtatg aagtagcgac agttttcttt ggtaacagct
    45121 gggaaagtaa tccagatgct aaggaattca cgctagacat cattcacgat atgaaacgcc
    45181 gtgtagaaga gtggtcagac caatatggct accatttctc tatctactca acaccatccg
    45241 aaagtctgac agaccgtttc tgccgactag atatagacaa gtttggctct attcctgata
    45301 tcacagacaa ggaatactac accaactctt tccactacga tgttcgtaaa aatccaacac
    45361 cgtttgaaaa attggacttt gagaaagtct atccagaagc aggtgcgtca ggtggtttca
    45421 tccattattg tgagtatcca gtccttcagc aaaatccaaa ggccttggaa gctgtctggg
    45481 attatgctta tgaccgtgta ggctatctag gcaccaatac tccgattgac cgttgctaca
    45541 agtgtgactt tgaaggggat tttgaaccaa ctgagagagg gtttgcttgt ccaaactgtg
    45601 gcaatagcga tcctaaaaca gtagacgttg ttaaacggac ttgtggctat cttggcaatc
    45661 ctcaagcgag accaatggtt aacgggcgtc acaaggaaat cgctgcgcgt gtcaaacata
    45721 tgaatggttc aacgattaaa atagctgggc atcaagtaac aaattagaaa gaaatgaaat
    45781 gggaaaatat caactagacg ataaggggcg cgcacaagtg acccgttatc acgagaaaca
    45841 ctctaaaggt ggagctggta agaaagaacg cttgcttagc ttcagagaac aatttttaaa
    45901 caagaacaag aaaaaataaa agtgagagcc agctctcgct tttctcatag tgggaggtag
    45961 ggatggaatt acgcagacca agattagcgg ataagaaagc tgttttagat atgatgacag
    46021 agtttgaaaa gagccaatca gcccatgatg gaggattttg ggatgttgag gatttttctt
    46081 acgaggagtg gctagaaggt aaccgtaata aagaaatggg aatatggcta cctgaaaatc
    46141 gcgttccatc gatacagttc gtattgtttg gtgaatcagg ttgtgctcta ggatttttga
    46201 atctgcgatt gagactgaat gaggggttac tgaattatgc tggccacatt ggctactcca
    46261 ttcgtccatc tgaaagaggc aagggttatg caaaagagac tctccgtcag ggcttgcaag
    46321 ttgctaagga aaagaacatc aagaaagctc tggtgacctg tagcgtgaat aatcctgcta
    46381 gcagagcagt cattctagca aatggtggaa tatttgagga tgctcgcaat ggagtcgagc
    46441 gttattggat agaggtagcg aatgaataat ccaaaaccac aagaatggaa aagcgaggaa
    46501 cttagtcaag gtcgtatcat tgactacaag gcctttaact ttgtggacgg agaaggcgtg
    46561 cgcaactctc tctatgtagc aggttgcatg tttcactgcg aggggtgtta taatgtagcg
    46621 acctggtcct tcaatgcagg cattccctat acagctgagt tggaagaaca gattatggca
    46681 gatcttgccc agccttatgt tcaggggtta accttactag gaggggagcc ttttcttaat
    46741 actgggattc tcttgccact tgttaagcgg attcggaagg aattgccaga caaggacatc
    46801 tggtcctgga cgggctacac ttgggaagaa atgatgttgg aaactccaga taaactggaa
    46861 ctcttgtcac tgattgacat tcttgtcgat ggaagatatg atcgaactaa gagaaatctt
    46921 atgctccagt ttcgaggttc gtccaaccaa cgaattatcg atgtgcaaaa atcgctcaaa
    46981 agtgggcaag tagtgatttg ggacaagctc aatgacggaa aagaaagcta tgaacaggtg
    47041 aagagagaat gaagaaaaaa gacttagtag accaactagt ctcagagatc gagacgggga
    47101 aagtcaggac actgggaata tacggtcatg gagcttcagg taaatcaacc tttgcacagg
    47161 aattgtacca agctttagat tctactacag taaatttgct agagacagat ccttatatca
    47221 cctcaggacg ccatctggta gtacccaagg acgcgccgaa tcaaaaggtg acagccagtc
    47281 tgccagtggc gcatgaactg gagagtttgc agagagatat ccttgccttg caggcgggta
    47341 tggatgtctt gacaattgaa gaaccttgga aggctagtga ggtcttgtct ggagccaaac
    47401 caattttgat tgtcgaaggg atgtctgttg gctttctacc caaggaactc tttgaaaaaa
    47461 ccatctgttt ctacacggat gaggagaccg aattaaagcg acgccttgct agagatacga
    47521 ctgtgagaaa tcgcgatgca tcctttatat tggctagcca tcagatgaga cgggagcagt
    47581 atctgcgata ctataaagaa actgagtcta aggcggatat cttagtggac caatcagaag
    47641 ataaatttga tgtcaagagg acttaactta tgtatagaat gtatagaaga aatatagaag
    47701 aaaatcccta attttagaaa gaaaaagtag gaaaacagtt tcatcccaaa aaaacgaaaa
    47761 aacagcaaca aatcccttgc aatcgcaggg gctttgtgtt attctattat ggtgctgtaa
    47821 attacagcct tagttttgat gcaagaggtt gcgacacgct cggttgcatt gccacgcaac
    47881 accgcgtcgg ttttcttgtg gagctagcct attatcttaa atagacgaaa aggagaaaaa
    47941 gatggcaaac aaaaaaatcc gtatccgttt gaaagcttac gaacaccgta cgcttgacac
    48001 agcggctgca aaaatcgtag aatcagctac tcgtacaggt gcacaagttg cgggtccaat
    48061 cccacttcca actgaacgta gcctctacac aatcattcgt gcgactcaca aatacaaaga
    48121 ctctcgcgaa caatttgaaa tgcgtacaca caaacgtttg atcgatatcg ttaacccaac
    48181 tcaaaaaaca gttgatgcct tgatgaaatt ggatcttcca agtggtgtaa acgtagaaat
    48241 caaactttaa tctaaaatat aaaagagcag aggctggtgt ttcaatctaa ttgaacacgg
    48301 gctaaactcg gtgtgaaaaa gataaacttc ctagtgtctg ctagacactg cgtcagtttc
    48361 ctattttgac gttgagtttg acgtcctttg tatcttagac ttgagcataa aaaacgctcg
    48421 ttaaaaactt tttgaataaa aaatatagaa aaggaactat tttctcatga caaaaggaat
    48481 cttagggaaa aaagtgggaa tgactcaaat cttcactgaa gctggcgaat tgatccctgt
    48541 aacagttatt gaagcaactc caaacgttgt tcttcaagtt aaaactgttg aaacagacgg
    48601 atacaacgct atccaagttg gtttcgatga caaacgcgaa gtattgagca acaaacctgc
    48661 taaaggacat gtagcgaaag ctaacacggc tcctaagcgc ttcattcgtg aattcaaaaa
    48721 cgttgaaggc ttggaagttg gcgctgaaat cacagttgaa acattcgcag ctggagatgt
    48781 tgttgacgta acgggtactt ctaaaggtaa aggtttccaa ggtgttatca aacgccacgg
    48841 acaatcacgt ggaccaatgg ctcacggttc tcgttaccac cgtcgtccag gttctatggg
    48901 gcctgttgca cctaaccgcg tattcaaagg taaaaacctt gcaggacgta tgggtggcga
    48961 ccgcgtaaca attcaaaacc ttgaagttgt acaagttgtt ccagaaaaga acgttatcct
    49021 tatcaaaggt aacgtaccag gtgctaagaa atctcttatc actatcaaat cagcagttaa
    49081 agctggtaaa taataaagaa aggggaaatc agtcacaatg gcaaacgtaa cattatttga
    49141 ccaaactggt aaagaagctg gccaagttgt tcttagcgat gcagtatttg gtatcgaacc
    49201 aaatgaatca gttgtgtttg atgtaatcat cagccaacgc gcaagccttc gtcaaggaac
    49261 acacgctgtt aaaaaccgct ctgcagtatc aggtggtgga cgcaaaccat ggcgtcaaaa
    49321 aggaactgga cgtgctcgtc aaggttctat ccgctcacca caatggcgtg gtggtggtgt
    49381 tgtcttcgga ccaactccac gttcatacgg ctacaaactt ccacaaaaag ttcgtcgcct
    49441 agctcttaaa tcagtttact ctgaaaaagt tgctgaaaac aaattcgtag ctgtagacgc
    49501 tctttcattt acagctccaa aaactgctga atttgcaaaa gttcttgcag cattgagcat
    49561 cgattctaaa gttcttgtta tccttgaaga aggaaatgaa ttcgcagctc tttcagctcg
    49621 taaccttcca aacgtgaaag ttgcaactgc tacaactgca agtgttcttg acatcgcaaa
    49681 tagcgacaaa cttcttgtca cacaagcagc tatctctaaa atcgaggagg ttcttgcata
    49741 atgaatttgt atgatgttat caaaaaacct gtcatcactg aaagctcaat ggctcaactt
    49801 gaagcaggaa aatatgtatt tgaagttgac actcgtgcac acaaactttt gatcaagcaa
    49861 gctgttgaag ctgctttcga aggtgttaaa gttgccaatg ttaacacaat caacgtaaaa
    49921 ccaaaagcta aacgtgttgg acgttacact ggttttacta acaaaactaa aaaagctatc
    49981 atcacactta cagctgattc aaaagcaatc gagttgtttg ctgctgaagc tgaataatct
    50041 aaggaggaaa tatcgtggga attcgtgttt ataaaccaac aacaaacggt cgccgtaata
    50101 tgacttcttt ggatttcgct gaaatcacaa caagcactcc tgaaaaatca ttgcttgttg
    50161 cattgaagag caaggctggt cgtaacaaca acggtcgtat cacagttcgt caccaaggtg
    50221 gtggacacaa acgtttctac cgtttggttg acttcaaacg taacaaagac aacgttgaag
    50281 cagttgttaa aacaatcgag tacgatccaa accgttctgc aaacatcgct cttgtacact
    50341 acactgatgg tgtgaaagca tacatcatcg ctccaaaagg tcttgaagta ggtcaacgta
    50401 tcgtttcagg tccagaagca gatatcaaag tcggaaacgc tcttccactt gctaacatcc
    50461 cagttggtac tttgattcac aacatcgagt tgaaaccagg tcgtggtggt gaattggtac
    50521 gtgctgctgg tgcctctgct caagtattgg gttctgaagg taaatacgtt cttgttcgtc
    50581 ttcaatcagg tgaagttcgt atgattcttg gaacttgccg tgctacagtt ggtgttgtcg
    50641 gaaacgaaca acatggactt gtaaaccttg gtaaagcagg acgtagccgt tggaaaggta
    50701 tccgcccaac agttcgtggt tctgtaatga accctaacga tcacccacac ggtggtggtg
    50761 aaggtaaagc accagttggt cgtaaagcac catctactcc atggggcaaa cctgctcttg
    50821 gtcttaaaac tcgtaacaag aaagcgaaat ctgacaaact tatcgttcgt cgtcgcaacg
    50881 agaaataata ttaaactagt cgcttaagca actagtaaat ccgccagctc ggtagtgctc
    50941 cataggagcg caagccgctg tggtacaaca tttaaaggag aaaatataaa aatgggacgc
    51001 agtcttaaaa aaggaccttt cgtcgatgag catttgatga aaaaagttga agctcaagct
    51061 aacgacgaaa agaaaaaagt tattaaaact tggtcacgtc gttcaacgat cttcccaagt
    51121 ttcattggtt acactattgc agtttatgac ggacgtaaac acgtacctgt ttacatccaa
    51181 gaagacatgg taggccacaa acttggtgaa tttgcaccaa ctcgtactta caaaggtcac
    51241 gctgcagacg acaagaaaac acgtagaaaa taaggagaac ataaatggca gaaattactt
    51301 cagctaaagc aatggctcgt acagtacgtg tttcacctcg taaatcacgt cttgttcttg
    51361 ataacatccg tggtaaaagc gtagccgatg caatcgcaat cttgacattc actccaaaca
    51421 aagctgctga aatcatcttg aaagttttga actcagctgt agctaacgct gaaaacaact
    51481 ttggtttgga taaagctaac ttggtagtat ctgaagcatt cgcaaacgaa ggaccaacta
    51541 tgaaacgttt ccgtccacgt gcgaaaggtt cagcttcacc aatcaacaaa cgtacagctc
    51601 acatcactgt agctgttgca gaaaaataag gaggtaaaat cgtgggtcaa aaagtacatc
    51661 caattggtat gcgtgtcggc atcatccgtg attgggatgc caaatggtat gctgaaaaag
    51721 aatacgcgga ttaccttcat gaagatcttg caatccgtaa attcgttcaa aaagaacttg
    51781 ctgacgcagc agtttcaact attgaaatcg aacgcgcagt aaacaaagtt aacgtttcac
    51841 ttcacactgc taaaccaggt atggttatcg gtaaaggtgg tgctaacgtt gatgcactac
    51901 gtgcaaaact taacaaattg actggaaaac aagtacacat caacatcatc gaaatcaaac
    51961 aacctgattt ggatgctcac cttgtaggtg aaggaattgc tcgtcaattg gagcaacgtg
    52021 ttgctttccg tcgtgcacaa aaacaagcaa tccaacgtgc aatgcgtgct ggagctaaag
    52081 gaatcaaaac tcaagtatca ggtcgtttga acggtgcaga tatcgcccgt gctgaaggat
    52141 actctgaagg aactgttccg cttcacacac ttcgtgcaga tatcgattac gcttgggaag
    52201 aagcagatac tacatacggt aaacttggtg ttaaagtatg gatctaccgt ggtgaagttc
    52261 ttccagctcg taaaaacact aaaggaggta aataaccaat gttagtacct aaacgtgtta
    52321 aacaccgtcg tgaattccgt ggaaaaatgc gcggtgaagc aaaaggtgga aaagaagtag
    52381 cattcggtga atacggtctt caagctacaa ctagccactg gatcactaac cgccaaatcg
    52441 aagctgctcg tatcgccatg actcgttaca tgaaacgtgg tggtaaagtt tggattaaaa
    52501 tcttcccaca caaatcatac actgctaaag ctatcggtgt gcgtatggga tctggtaaag
    52561 gggcacctga aggttgggta gcaccagtta aacgtggtaa agtgatgttc gaaatcgctg
    52621 gtgtatctga agagattgca cgtgaagcgc ttcgacttgc tagccacaaa ttgccagtta
    52681 aatgtaaatt cgtaaaacgt gaagcagaat aaggagaagg catgaaactt aatgaagtaa
    52741 aagaatttgt taaagaactt cgtggtcttt ctcaagaaga actcgcgaag cgcgaaaacg
    52801 aattgaaaaa agaattgttt gaacttcgtt tccaagctgc tactggtcaa ttggaacaaa
    52861 cagctcgctt gaaagaagtt aaaaaacaaa tcgctcgtat caaaacagtt caatctgaag
    52921 cgaaataata gactagggaa ggagaaattt caatggaacg caataatcgt aaagttcttg
    52981 ttggacgtgt tgtatctgac aaaatggaca agacaatcac agttgtagtt gaaacaaaac
    53041 gtaaccaccc agtctatggt aaacgtatta actactctaa aaaatacaaa gctcatgatg
    53101 aaaacaatgt tgccaaagaa ggtgatatcg tacgtatcat ggaaactcgc ccgctttcag
    53161 ctacaaaacg tttccgtctt gtagaagttg ttgaagaagc ggtcatcatc taatcaaacc
    53221 tgaaaggaga aaactgaaat gattcaaaca gaaactcgtt tgaaagtcgc agacaacagc
    53281 ggtgctcgcg aaatcttgac tatcaaagtt cttggtggtt caggacgtaa atttgcaaac
    53341 atcggtgatg ttatcgtggc atctgtaaaa caagctactc ctggtggtgc ggttaaaaaa
    53401 ggtgacgttg ttaaagcagt tatcgttcgt actaaatcag gtgctcgtcg tgctgatggt
    53461 tcatacatca aatttgacga aaacgcagca gttatcatcc gtgaagacaa aactcctcgc
    53521 ggaacacgta tctttggccc agttgcacgt gaattgcgtg aaggtggttt catgaagatc
    53581 gtgtcacttg ctccagaagt actttaattt ttaggaacaa actagtcccc tagcttcaag
    53641 ctagggtgcc cttatgggcg taagaaaaat caaggagaaa cctaatgttt gtaaaaaaag
    53701 gcgacaaagt tcgcgtaatc gctggtaaag ataagggaac agaagctgtt gtccttactg
    53761 cccttccaaa agtaaacaaa gttatcgttg aaggtgttaa cattgttaag aaacaccaac
    53821 gtccaactaa cgagcttcct caaggtggta tcatcgagaa agaagcagct atccacgtat
    53881 caaatgttca agttttggac aaaaatggtg tagctggtcg tgttggttac aaatttgtag
    53941 acggtaaaaa agttcgctac aacaaaaaat caggcgaagt gcttgattaa tcacgaagga
    54001 aaggagaagt ataatggcaa atcgtttaaa agaaaaatat cttaatgaag tagttcctgc
    54061 tttgacagaa caattcaact actcatcagt gatggctgtg cctaaagtag ataagattgt
    54121 tttgaacatg ggtgttggtg aagctgtatc aaacgctaaa agccttgaaa aagctgctga
    54181 agaattggca cttatctcag gtcaaaaacc acttatcact aaagctaaaa aatcaatcgc
    54241 cggcttccgt cttcgtgaag gtgttgcgat cggtgcaaaa gttacccttc gtggtgaacg
    54301 tatgtacgaa ttcttggata aattggtatc agtttcactt ccacgtgtac gtgacttcca
    54361 cggtgtccca acaaaatcat ttgatggacg cgggaactac acacttggtg tgaaagaaca
    54421 attaatcttc ccagaaatca acttcgatga cgttgacaaa actcgtggtc ttgacatcgt
    54481 tatcgtaaca actgctaaca ctgacgaaga gtcacgtgca ttgcttacag gccttggaat
    54541 gccttttgca aaataatata ggaggtaaat ctaatggcta aaaaatcaat ggtagctaga
    54601 gaggctaaac gccaaaaaat tgttgaccgt tatgctgaaa aacgtgctgc attaaaggcg
    54661 gcaggggact acgaaggttt atctaaatta cctcgcaacg cctcaccgac tcgtttacat
    54721 aatcgttgta gagttacggg gcgcccacat tcagtttacc gcaaatttgg tctgagtcgt
    54781 atcgcttttc gcgaacttgc gcataaaggt caaattcctg gtgtaacaaa agcatcttgg
    54841 taatttaaga tatcaagggt gtcaaaactc caagtaaaaa taggaaactt gacgaagaaa
    54901 ctaaagtttc taggaaagtt tatctttttc acacagagtt tagcccgggt tcaattgggc
    54961 ttgccaattt gaacccgagc tacagctttg gcaaaaaaga ccaatttgct ttggagcatt
    55021 gcttctgcat taaattgtct atttttgctc gtgctgttac gctctttgta tcatgtatta
    55081 actagcaagt gcaacttgca aactactagt aagaggagaa aaacaaaatg gttatgactg
    55141 acccaatcgc agacttccta actcgtattc gtaatgctaa ccaagctaaa cacgaagtac
    55201 ttgaagtacc tgcatcaaac atcaaaaaag ggattgctga aatccttaaa cgcgaaggtt
    55261 ttgtaaaaaa cgttgaaatc atcgaagatg acaaacaagg cgtcatccgt gtatttctta
    55321 aatacggacc aaatggtgaa aaagttatca ctaacttgaa acgtgtttct aaaccaggac
    55381 ttcgtgtcta caaaaaacgt gaagaccttc caaaagttct taacggactt ggaattgcca
    55441 tcctttcaac ttctgaaggt ttgcttactg ataaagaagc acgccaaaag aatgttggtg
    55501 gtgaggttat cgcttacgtt tggtaaaatc aagatacaaa gctcgtaaag aacaaagcaa
    55561 aattaggaag ttggagaagt ttgtttacaa acaagccaac ttatctattt tgcacagttc
    55621 ttagagcgtg ttcagttcag ctcttgaact aaataagtat ctgaaccccg tgaaaactgg
    55681 ccgttctggc ctgacaattt aacaggagaa aataaacatg tcacgtattg gtaataaagt
    55741 tatcgtgttg cctgctggtg ttgaactcgc taacaatgac aacgttgtaa ctgtaaaagg
    55801 acctaaagga gaacttactc gtgagttctc aaaagatatt gaaatccgtg tggaaggtac
    55861 tgaagtaact cttcaccgtc caaacgattc aaaagaaatg aaaactatcc acggaactac
    55921 tcgtgccctt ttgaacaaca tggttgttgg tgtatcagaa ggattcaaga aagaacttga
    55981 aatgcgtggg gttggttacc gtgcacagct tcaaggatct aaacttgttt tggctgttgg
    56041 taaatctcat ccagacgaag ttgaagctcc agaaggaatt acttttgaac ttccaaaccc
    56101 aacaacaatc gttgttagcg gaatttcaaa agaagtagtt ggtcaaacag ctgcttacgt
    56161 acgtagcctt cgttcaccag aaccatataa aggtaaaggt atccgttaca ttggtgaatt
    56221 cgttcgccgt aaagaaggta aaacaggtaa ataatgttga gtggttgatc atcaaccacc
    56281 aacctatttt ccaactttgt gcatagcaca cgatttaaaa ctaaagaggt gaaaactgtg
    56341 atttcaaaac cagataaaaa caaactccgc caaaaacgcc accgtcgcgt tcgcggaaaa
    56401 ctctctggaa ctgctgatcg cccacgtttg aacgtattcc gttctaatac aggcatctac
    56461 gctcaagtga ttgatgacgt agcgggtgta acgctcgcaa gtgcttcaac tcttgataaa
    56521 gaagtttcaa aaggaactaa aactgaacaa gccgttgctg tcggtaaact cgttgcagaa
    56581 cgtgcaaacg ctaaaggtat ttcagaagtg gtgttcgacc gcggtggata tctatatcac
    56641 ggacgtgtga aagctttggc tgatgcagct cgtgaaaacg gattgaaatt ctaataggag
    56701 gacactagaa aatggcattt aaagacaatg cagttgaatt agaagaacgc gtagttgctg
    56761 tcaaccgtgt tacaaaagtt gttaaaggtg gacgtcgtct tcgtttcgca gctcttgttg
    56821 ttgttggtga ccacaatggt cgcgtaggat ttggtactgg taaagctcaa gaagttccag
    56881 aagcaatccg taaagcagta gatgatgcta agaaaaactt gatcgaagtt cctatggttg
    56941 gaacaacaat cccacacgaa gttctttcag aattcggtgg agctaaagta ttgttgaaac
    57001 ctgctgtaga aggttctgga gttgccgctg gtggtgcagt tcgtgccgtt gtggaattgg
    57061 caggtgtggc agatattaca tctaaatcac ttggttctaa cactccaatc aacattgttc
    57121 gtgcaactgt tgaaggtttg aaacaattga aacgcgctga agaaattgct gcccttcgtg
    57181 gtatttcagt ttctgatttg gcataagaaa ggggataaaa tggctcaaat taaaattact
    57241 ttgactaagt ctccaatcgg acgcattcca tcacaacgta aaactgttgt agcacttgga
    57301 cttggcaaat tgaacagctc tgttattaaa gaagataacg ctgctatccg tggtatgatc
    57361 acagcagtat ctcacttagt aacagttgaa gaagtaaact aatgaagttt taggggatgt
    57421 gcactgtacc atcccctaaa actagatata gtcatctatg atgacatcgt ataggcgagt
    57481 tgatggggga gacaaccttt tctcccttat cggcgctagc attttacaaa agaggagaaa
    57541 ataaaaatga aacttcatga attgaaacct gcagaaggtt ctcgtaaagt acgtaaccgc
    57601 gttggtcgtg gtacttcatc aggtaacggt aaaacatctg gtcgtggtca aaaaggtcaa
    57661 aaagctcgta gcggtggcgg agttcgcctt ggttttgaag gtggacaaac tccattgttc
    57721 cgtcgtcttc caaaacgtgg attcactaac atcaacgcta aagaatacgc aattgtgaac
    57781 cttgaccaat tgaacgtctt tgaagatggt gctgaagtaa ctccagttgt tcttatcgaa
    57841 gcaggaattg ttaaagctga aaagtcaggt attaaaattc ttggtaacgg tgagttgact
    57901 aagaaattga ctgtgaaagc agctaaattc tctaaatcag ctgaagaagc tatcactgct
    57961 aaaggtggtt cagtagaagt catctaagag aggtgaccta tgttttttaa attattaaga
    58021 gaagctctta aagtcaagca ggttcgatca aaaattttat ttacaatttt tatcgttttg
    58081 gtctttcgta tcggaactag cattacagtt cctggtgtga atgccaatag cttgaatgct
    58141 ttaagtggat tatccttctt aaacatgttg agcttggtgt cggggaatgc cctaaaaaac
    58201 ttttcgattt ttgccctagg agttagtccc tatatcaccg cttctattgt tgtccaactc
    58261 ttgcaaatgg atattttacc caagtttgta gagtggggta aacaagggga agtaggtcga
    58321 agaaaattga atcaagctac tcgttatatt gctctagttc tcgcttttgt gcaatctatc
    58381 gggattacag ctggttttaa taccttggct ggagctcaat tgattaaaac tgctttaact
    58441 ccacaagttt ttctgacgat tggtatcatc ttaacagctg gtagtatgat tgtcacttgg
    58501 ttgggtgagc aaattacaga taagggatac ggaaacggtg tttccatgat tatctttgcc
    58561 gggattgttt cctcaattcc agagatgatt cagggcatct atgtggacta ctttgtgaac
    58621 gtcccaagta gccgtatcac ttcatctatc attttcgtaa tcattttgat tattactgta
    58681 ttgttgatta tttactttac aacttatgtt caacaagcag aatacaaaat tccaatccaa
    58741 tatactaagg ttgcacaagg tgctccatct agctcttacc ttccgttaaa ggtaaatcct
    58801 gctggagtta tccctgttat ctttgccagt tcgattactg cagcgcctgc ggctattctt
    58861 cagtttttga gtgccacagg tcatgattgg gcttgggtaa gggtagcaca agagatgttg
    58921 gcaactactt ctccaactgg tattgccatg tatgctttgt tgattattct ctttacattc
    58981 ttctatacgt ttgtacagat taatcctgaa aaagcagcag agagcctaca aaagagtggt
    59041 gcctatatcc atggagttcg tcctggtaaa ggtacagaag aatatatgtc taaacttctt
    59101 cgtcgtcttg caactgttgg ttccctcttc cttggtgtga tttccatttt accgattgca
    59161 gctaaagatg tatttggtct ttctgatgtt gttgcctttg gtggaacaag tctcttgatc
    59221 attatctcta caggtatcga aggaatcaag caattggaag gttacctatt gaaacgtaag
    59281 tatgttggtt tcatggacag aacagaataa aagtatttac tgaatcagta aatgctgagg
    59341 gagtggaggt ttaaactctg acatttgtaa gagttggatc tcccctcttc tattttgttt
    59401 ttaaataggg gtgaaaagac tttttgcttc tatttaaaaa taaaataagg agatcaaatc
    59461 atgaatcttt tgattatggg cttacctggt gcaggtaagg gaactcaagc agcaaaaatc
    59521 gtagaacaat tccatgttgc acatatctca acaggtgata tgttccgcgc tgcaatggta
    59581 aatcaaactg aaatgggtgt tcttgctaag tcatatattg acaagggtga attggttcct
    59641 gacgaagtta caaatggaat cgtaaaagaa cgtctttcac aagatgatat taaagaaaca
    59701 ggattcttat tggatggtta cccacgtaca attgaacaag ctcatgcctt ggacaaaaca
    59761 ttggctgaac ttggcattga actagaaggt gttatcaata ttgaagtgaa ccctgacagc
    59821 ctcttggaac gtttgagtgg ccgtatcatc caccgcgtaa ctggagaaac tttccacaag
    59881 gtctttaacc caccagttga ctataaagaa gaagattact accaacgtga agatgataag
    59941 cctgagacag taaaacgtcg tttggatgtt aatattgctc aaggagaacc aatcattgct
    60001 cactaccgtg ccaaaggttt ggttcatgac atcgaaggta atcaagatat caatgatgtc
    60061 ttctcagata ttgaaaaagt attgacaaat ttgaaataaa gcgtttttca cacttgcaaa
    60121 aatccgctac aaatgttata ctgagatagt ctgacttata attgttgtct ctgtgtctag
    60181 aggcatcgaa tcgaaattta tggaggtgct tttgcgtggc aaaagacgat gtgattgaag
    60241 ttgaaggcaa agtagttgat acaatgccga atgcaatgtt tacggttgaa cttgaaaatg
    60301 gacatcagat tttagcaaca gtttctggta aaattcgtaa aaactatatt cgtattttag
    60361 cgggagatcg tgttactgtc gaaatgagtc catatgactt gacacgtgga cgtatcactt
    60421 accgctttaa ataatcgaaa aacttggagg gataagaaat gaaagtaaga ccatcggtca
    60481 aaccaatttg cgaatactgt aaagttattc gtcgtaatgg tcgtgttatg gtaatttgcc
    60541 cagcaaatcc aaaacacaaa caacgtcaag gataagatag aaaggagaaa acatggctcg
    60601 tattgctgga gttgatattc caaatgacaa acgcgtagta atctcattga cttatgttta
    60661 tggtatcgga cttgcaacat ctaagaaaat tttggctgct gctggaatct cagaagatgt
    60721 tcgtgtacgt gatcttacat cagatcaaga agatgctatc cgtcgtgaag tggatgcaat
    60781 caaagttgaa ggtgaccttc gtcgtgaagt aaacttgaac atcaaacgtt tgatggaaat
    60841 cggttcatac cgtggtatcc gtcaccgtcg tggacttcct gtccgtggac aaaatactaa
    60901 aaacaacgct cgcactcgta aaggtaaagc tgttgcgatt gctggtaaga aaaaataata
    60961 taggaggtaa aagtcttggc taaaccaaca cgtaaacgtc gtgtgaaaaa gaatatcgaa
    61021 tctggtattg ctcatattca cgctacattt aataacacta ttgttatgat tactgatgtg
    61081 catggtaatg caattgcttg gtcatcagct ggtgctcttg gtttcaaagg ttctcgtaaa
    61141 tctacaccat tcgctgctca aatggcttct gaagctgctg ctaaatctgc acaagaacac
    61201 ggtcttaaat cagttgaagt tactgtaaaa ggtccaggtt ctggtcgtga gtcagctatt
    61261 cgtgcgcttg ctgccgctgg tcttgaagta acagcaattc gtgatgtgac tccagtgcca
    61321 cacaatggtg ctcgtcctcc aaaacgtcgc cgtgtataat catcgcatta cactgctttt
    61381 cgtttaagag ggagtaacta aatgatcgag tttgaaaaac caaatataac aaaaattgat
    61441 gaaaataaag attatggcaa gtttgtaatc gaaccacttg aacgtggcta cggtacaact
    61501 cttggtaact ctcttcgtcg tgtacttcta gcttctctac caggagcagc tgtgacatct
    61561 atcaacattg atggtgtgtt acatgagttt gacacagttc caggtgttcg tgaagacgtg
    61621 atgcaaatca ttctgaacat taaaggaatt gcagtgaaat cgtacgttga agacgaaaaa
    61681 atcatcgaac tggatgttga aggtcctgct gaagtaacag ctggtgacat tttgacagat
    61741 agcgatattg aaattgtaaa tccagatcat tatctcttta caatcggtga aggttcttct
    61801 ctaaaagcga ctatgactgt taacagtggt cgtggatatg tacctgctga tgaaaataaa
    61861 aaggataatg caccagttgg aacacttgct gtagattcta tttatacacc agttacaaaa
    61921 gtcaactatc aagtggaacc tgctcgtgta ggtagcaatg atggtttcga caaattaacc
    61981 cttgaaatct tgacaaatgg aacaattatt ccagaagatg ctttagggct ttcagcacgt
    62041 attttgacag aacatcttga tttgtttaca aatcttactg agattgctaa gtcaactgaa
    62101 gtgatgaaag aagctgatac tgaatctgac gaccgtattt tagatcgtac gattgaggaa
    62161 ctggacttgt ctgtgcgttc atacaactgt ttaaaacgtg ccggtatcaa tactgtgcat
    62221 gatttgacag aaaaatctga agcagagatg atgaaagtac gaaatcttgg acgcaagagt
    62281 ttggaagaag tgaaactcaa actcattgat ttgggtcttg gattaaaaga taaataaagg
    62341 aggaatacat ggcttaccgt aaactaggac gcactagctc acaacgtaaa gcaatgcttc
    62401 gcgatttgac aactgacctt ttgatcaacg aatcaatcgt gacaactgaa gctcgtgcta
    62461 aagaaatccg taaaactgtt gaaaaaatga ttactctagg taaacgtggt gatttgcatg
    62521 cacgtcgtca agcagctgct ttcgtacgta atgaaatcgc atctgaaaac tatgatgaag
    62581 caactgataa gtacacttct actacagcac ttcaaaaatt gttctcagaa atcgcacctc
    62641 gttatgctga acgtaacggt ggatacactc gtatccttaa aactgaacca cgtcgtggtg
    62701 atgcagcgcc aatggcgatc atcgaattag tataaaatca tcaattttgt tgagtgttat
    62761 gatgatggag tcttgtgctc ttagtctagc tctggtctac cgctaggatt tcggtcctag
    62821 cgggaacact catcataagt tgggatagta gacgcttgtt tacgaaattg tttttttctt
    62881 aagaacaact tcgtaagcag gcgtttttga gtattttcgt tagaattatg ctatactatt
    62941 tgaaaagaat cctgtttaat gttaaggttt cttattttaa gaagaattgg agtttactta
    63001 tgaaagccat tataactgtt gttggtaaag ataaatctgg aattgttgca ggtgtttctg
    63061 gtaaaattgc agaattagga ttgaatattg acgatatctc tcaaactgtc ttggatgaat
    63121 attttacgat gatggctgtt gtatctagtg atgaaaagca agattttacc tatcttcgta
    63181 atgaatttga agcttttggg caaactttga atgtaaaaat caatattcag agtgcagcga
    63241 ttttcgaagc tatgtataat atctaggagg ttatcatgga tattagacaa gttactgaaa
    63301 ccatcgccat gattgaggag caaaacttcg atattagaac cattaccatg gggatttctc
    63361 ttttggactg tatcgatcca gatatcaatc gtgctgcgga gaaaatctat caaaaaatta
    63421 cgacaaaggc ggctaattta gtagctgttg gtgatgaaat tgcggctgag ttgggaattc
    63481 ctatcgttaa taagcgtgta tcggtgacac ctatttctct gattggggca gcgacagatg
    63541 cgacggacta cgtggttctg gcaaaagcgc ttgataaggc tgcgaaagag attggtgtgg
    63601 actttattgg tggtttttct gccttagtac aaaaaggtta tcaaaaggga gatgagattc
    63661 tcatcaattc cattcctcgc gctttgactg agacggataa ggtctgctcg tcagtcaata
    63721 tcggctcaac caagtctggt attaatatga cggctgtggc agatatggga cgaattatca
    63781 aggaaacggc aaatctttca gatatgggag cggccaagtt ggttgtattc gctaatgctg
    63841 ttgaggacaa tccatttatg gcgggtgcct ttcatggtgt tggggaagca gatgttatca
    63901 tcaatgtcgg agtttctggt cctggtgtgg tgaaacgtgc tttggaaaaa gttcgtggac
    63961 agagctttga tgtagtagcc gaaacagtta agaaaactgc ctttaaaatc actcgtatcg
    64021 gtcaattggt tggtcaaatg gccagtgaga gactgggtgt ggagtttggt attgtggact
    64081 tgagtttggc accaacccct gcggttggag actctgtggc acgtgtcctt gaggaaatgg
    64141 ggctagaaac agttggcacg catggaacga cagctgcctt ggccctcttg aacgaccaag
    64201 ttaaaaaggg tggagtgatg gcctgtaacc aggtcggtgg tctatctggt gcctttatcc
    64261 ctgtttctga ggatgaagga atgattgctg cagtgcaaaa tggctctctt aatttagaaa
    64321 aactagaagc tatgacggct atctgttctg ttggattgga tatgattgcc atcccagaag
    64381 atacgcctgc tgaaactatt gcggctatga ttgcggatga agcagcaatc ggtgttatca
    64441 acatgaaaac aacagctgtt cgtatcattc ccaaaggaag agaaggcgat atgattgagt
    64501 ttggtggtct attaggaact gcacccgtta tgaaggttaa tggggcttcg tctgtcgact
    64561 tcatctctcg cggtggacaa atcccagcac caattcatag ttttaaaaat taagaaaata
    64621 ggagaaattt taagttctat ttaagattag atgtgtatac tataatcatt aaataaagac
    64681 ctcctaatat tatttgaaac agataacact gaattagttt gaatttgatt ttcatctaat
    64741 atctttattt aatgaactcc taaacttttt cataataatc tccttcaaaa gtcgcctgta
    64801 tgggtggctt ttattttatc attcatgata taatagaagc aaacggagga cggaaaatgg
    64861 taaaagtacg attgtatttg gtacgtcatg gcaagaccat gtttaacacg attggtcgcg
    64921 cgcaaggttg gagcgatact cccttaactg ctgaaggtga acgagggatt caagagttag
    64981 gaactggttt gcgagaatct gatctacagt ttgagcgcgc ttattcgagt gattctggtc
    65041 gtaccattca gaccatggga attatccttg aagaacttgg cttgcagggg aaaatccctt
    65101 atcgcatgga caagcgtatc agagaatggt gtttcggtag ttttgatgga gcctatgatg
    65161 gcgatctttt catgggcatt attcctcgta tctttaatgt ggaccacgtt caccaattgt
    65221 cttatgctga actggctgag ggcttggtag aggtcgatac agctggttgg gctgaaggct
    65281 gggaaaaact cagtggccga atcaaggaag gctttgaaat gattgcaaaa gaaatggaag
    65341 atcaaggtgg aggtaacgcc cttgttgtca gccatggaat gactattgga accattgttt
    65401 atctgattaa tggcatgcat ccgcatggtc tagataatgg tagcgtgacg attcttgaat
    65461 atgaggacgg tcagtttagg gttgaagttg tcggtgaccg tagttaccga gagctaggac
    65521 gtgagaagat ggaagaaggc tctatttaat cagtctagac ttgcttgcca tgagctaggg
    65581 atttgataag aatatcaaga taagaaaaaa cagccgaggg tactcctttc ggctgttttt
    65641 gatgtggaaa actaaagtgt aatgctattg cttttagaga ttttcataaa caagagcaag
    65701 gaacctactg ttagaacagt caggatagtt gacaaggctg cggctacacc gtaatttcct
    65761 ctgagaacct ctgtataaat agctacagtc attgttcttg ttttgacatt gtagaggagg
    65821 atagaagtag agagttttga aatcattgtg acccaagata agatggctcc agaaatgata
    65881 ccagatagca tcattggagt tgtaatctta gcaaaggtat tgagacgact acttcctaag
    65941 ctttcagcag cttcttcaat acttggtgct atttgttgta agctagcaac agatgagcga
    66001 atagtataag gtaatcttct gacagataga gacataatca agatgaaagc agtccctgta
    66061 atcataagaa atccacttcc aaatagacca gagaaatgaa ggcaatccct agaacggttc
    66121 ctggtacaat ataaggtacc atactgaggc tgtcaattaa gtttgtaaac aaattccgtt
    66181 ttctaacggc taggtaggag ataaatgtcg caaatagaac aactagaact aaggcaatca
    66241 aagggatacg aatggtattg aaaatagcag atcccatacg attgaaagct accttgtaac
    66301 tgtttggaga ataaccttta acaaatacca tacctgatgt ttttaggaaa gaggtataaa
    66361 ttaagtagat ttgaggtaaa acagagataa agataattcc gtagactgtt gcataaatgg
    66421 cagccatttt tccttttgta gtttttttag gctcaattgg atggatcaga ttcatgctga
    66481 aactgtagcg gtttgcaatg tgtttttgga taaggaaaat tgccaaggca atgataatcg
    66541 ccataattgc aaaagcagaa tttcctccaa cctcgctaat aaattgggta taaatcagga
    66601 cagggaaagt ccgatatcct tcgccaatca acataggcgt tccaaagtct gagaatgctc
    66661 tcataaatac aagcaaggag ctgctagtaa ggttggaact aggagaggta aaacaaccgt
    66721 tacgataggt ttaaatccga aggaccccat gctttcagct gcttcaagta gagaattgtc
    66781 aatactgttc attgttccag caacatatag aaataccagt gggaatagtt gcagtgtaaa
    66841 gacaagtaca attcctttga atccataaat atcgatagct ggaagatgaa gggcatttgt
    66901 caaaaattta gtgatgacct catttcgtcc cagcaagaga atccaggagt aggctcctac
    66961 gaaaggagct gacatggaag caatgataat caatatttgt agaaatttct tccccttgaa
    67021 gtcatacata gagaagagat aagctaatag ggttcctaca actaaggaag tgatagtagc
    67081 ggtaatggaa accttgaaac tgttgactag tgtctcagag tagtaggctt tactaaagaa
    67141 agtgacaaaa ttagctagtg agaattgtcc ttcatgtata agtgcttgct tgagcacggt
    67201 aacgatagga taaacgagaa agataggata ggtaagaaag aggaagaaag aggaagctgt
    67261 ccaaatattt agttttttac gttccatggt tgactccttt tatcaggttt tgggaaccat
    67321 ctgcagaaaa gatgtttaat ttttgcgtat tgattcgtag acgaatacga ttgccttttt
    67381 gtagatcttc ttcaaaagtt gattcttcac taacttgaat ttttgaggca aaacctgtct
    67441 caatgaaata atccgtattt agtccaagat agacgctatc tctaatagtt ccttcaatat
    67501 ctccagattc atctttgata aactcttcgg gacgaatgct tacatgaata gcttgctcct
    67561 caacctgatc aagagctggc attcgaaggg catagccatc tgaaaagacg atataagcgc
    67621 cgtcgctccg tttttcaaga ttggcaggga taatatttgt gcgtccgata aaggttgcca
    67681 caaactcatt agctggttta tgatagagtt cttttggtcg gccgatttgt tggatcaccc
    67741 catctttcat aacagcaatt tggtctgaaa tagccatggc ttcttcttgg tcgtgggtta
    67801 cataaacagt tgtaattccc acttcgtgtt ggatttctcg gatggcttga cgcatatcca
    67861 agcgaagttt ggcctccaga ttactaagtg gctcgtccat gaggagaaca cttggattaa
    67921 ccgctaaggc gcatgccaag gtgacacgtt gttgttgtcc accactgagt ttatcgggct
    67981 ttcaatccgc atattgagca atttgcatga gttcaagata cttgttggtc tgttgaatca
    68041 attcttcttt tggaaccttc ttttgcataa gaccaaaagc aacgttgtct cggacagtca
    68101 aatgtgggaa aatagcgtag ttttggaaaa ccatcccgat attgcgtttg ctgggttcca
    68161 tattattgat ttttgtatca tcgaagtaaa attctccatc tttgatactg ttgaaacctg
    68221 caatcatacg aagaagggtc gttttcccac atcctgaagc tccaagaagg gtaaagagac
    68281 ttccttttgg aattgtaatg ttcaaattct caataacagg gacatcgtgg tagatttttt
    68341 tggcgttaat aatttcgatc tcattcatag tgaacctctt ttactgttta gattggatat
    68401 ctgtaaagac ttcgttgtat ttcttaacga tatctgattt attcttgatg acataatcat
    68461 aatcttcagt gagtgttttg attttgtcaa ttggtttcat gttttcgctt gttttagcat
    68521 ttttacgaac aggacggtta gtagtggttg taccaagtgt atcttgtact tcttgagaga
    68581 taataaaatc gataaatttc ttggcatttt ccatattttt agctttttta acgatagcag
    68641 cactagcagg taggaagacg gttccttctt ttggatagac taccttaatg ttagctccgt
    68701 catttaagag tttaactgct ggatcttcat aagagagacc aacagccatt tctccatcag
    68761 cgactgcttt atagacacca gatgaactta aaccgatttt atagtatatt gaaactagaa
    68821 tagtacacat ctacttctaa aatattgtta gaaatcgatt tgactgtcct gattgatttg
    68881 tcctgttctt atttcatttt actataccat caataagtgt gaaaagatct tttacataag
    68941 accaagcctt atcatctttg taaccacctt gatcttgtag catatttgtt aattgagcaa
    69001 aggcgctaga agagtttgct gggtcagcag ttgcgatttt tccttttagt tcaggtttga
    69061 gaaggtcgct atatccttcg atgttcatgc ctttagttaa atcagggtgg acgattaaaa
    69121 cactaccatc tagtgtataa ggagtagaga agccagttgt gttttgatat tctttgataa
    69181 cattatcatt ttcttttgaa atatagtttt caaagagttc tccgtgggta gcatattgtg
    69241 tataagaacc accaaagata acatcagcta caggaacttc tttttctgac tctagttttt
    69301 tgaaaagttc tccagtacca gcttgaatca gttctatttt gataccatat ttttcttcaa
    69361 aggcaggaat agttgctcca attaagcctt ctgagtttgg tcaataaacg actagcgaac
    69421 caccgtctcc tttatcagat gaactgtcat cggcagattc attagaagaa caagcagcat
    69481 aatacatcca tttctttttc atgatggata cctccgttgt gttatttaag tttattttaa
    69541 aacaatgtaa gcgtttttaa aacctacaat tctattctat agtgtattga atctataaca
    69601 gtacaccttg actgctaaaa tatttctata aattaatttg actttcctga tagagatgtt
    69661 cacatcttat ttcaattcac tatattaggg taaaattctc tacaaaaaga agaatagcct
    69721 attttactat tcttccgagt gatttcaatt tctttgggga aatatggaga tactttttaa
    69781 atactttggc aaaatattta tagtctgaaa atccaacttg gtcagagata gcgcttaaag
    69841 gggagttggg agattcagcc atcttatcta tagcttgttt caggcgatat tgtaagatat
    69901 attcatttag agtcatcttt gataacctta tatagatagc tttcgctata gtttaaagct
    69961 tcagcaatag taatgctcta catagtgctt gtggacaaag gagataattt gttgaatgat
    70021 ttggttttgt gtatcaacct gttggataga ggtgagtaaa gtttgatatt cttctaaaaa
    70081 aggagtttct tgagatgtgc taatttgtaa tcgcaaaaca attttttgaa gacattctgt
    70141 caattccttg gtatcaattg gcttggataa gaaatcaact gctccatatt gcatggcttt
    70201 ttggcatttt gaaaatcgtt ataacctgat aagataactt tttcataaga aagagtacga
    70261 gtggctttga acatcataaa agcatccata attggcattg tgatgtctgt taagacaaat
    70321 atgaggttct ttttcttgga tgagtttcat tccctcttga ccgtgactgg cagttcctac
    70381 gacttggatg cctaaggcag agtagtctac ggcaatctct agccattttc ggatgaggtg
    70441 ttcatcttct acaataatga gcttaaacat gagttagtct ttcgttacaa atttgaccca
    70501 agtttctcct tggcgattga ctcctaaatc tagctggaca tcagaaaaga aattgctcaa
    70561 tcgtttgtag ctgttcacga tgccatgctg ggtatgaggg ctttctaaag agtctaaaat
    70621 agcgaatcgc tcttgtttgg tgagtccttc agcattatcc ttgactaaaa aagttagaga
    70681 atctgcttcc aaggtaatgt ggatatcaat atgaagatca atacggtatt gcatcccatg
    70741 ttttatagca ttttctacta gaggaagcaa gaaaagttta gggataggct gattatcgac
    70801 agtttctggg cagacaatat cataggaaaa ctgctcgaaa cgaatcttat gaatcataag
    70861 gtaatcctct ataatcttta aatcctgaca aatggttgtt tctttttcta aatcggtgat
    70921 actgtatcgg agaatgcgcg tgaggtcaca aaggctgcga tagagcttct atggagaatt
    70981 tctttttgga gaaatttttt aaaggaatga gacatccgct acctccttgg aagggttttt
    71041 tgtgataagt atagcagttt aaaaattcta gagcaaggta aaatagaaaa ggtttggcta
    71101 aaatttttta gctaaacctt ttgaaaagtt aagtatgtat tatagatgct tgttatctgc
    71161 aaatagctag agcatttcaa ggaaatgaac tagaaataac aattaatatg gtggttcaga
    71221 aatacctttt gataatcaat aagatcttca ggatgaagtg cgttgactcc atccatttca
    71281 tatttccgat ttaataaacg atatttgttt tcaccaaatt gatgaaaagg gagtagttga
    71341 acttggtcga tatttaatga gttaaataga gtagcgaatt tttctgcatc ctctaaacta
    71401 ttgttaaaat taggaataac tgggattctt aaaacgatag ttttattttg agaaaaagca
    71461 taatgaatgt ttttaataat catttgatta aaaaccccag tcactttttt atgttttata
    71521 gaattataat gttttaggtc tgtgtagata aaatccacat attgaattaa atcaataaat
    71581 ttttcatgat caacaaaggc agtagtttca atggcagtgt gtatgtgatg ttctttagct
    71641 gattttaaga tggctttagc aaattcaaac tgagcaaata tttcacctcc tgataaagtt
    71701 aaacctccac cggattcttc gtaaaattct ttgtctttta atacctctgt aataatttct
    71761 tctacagtct tttcttcacc gactaaggtg aatttctctc gttgagcatc tttcattttt
    71821 tcaggtttca ttctttgaga ttcaggatta gaacaccatg gacagcgcag aggacatcct
    71881 tttaaaaaaa cagttgtacg aatacccggg ccgtcatgaa ttgaaaagtg ttgaatatta
    71941 aaaataattc ctttagatat ttccataaga gttcctcctc ttcataagtc tatcctatca
    72001 caaaaacgaa agaaaaacaa ttacgaacga aagtttaatt tgttgttttt tgctttttat
    72061 tttggtagaa taaaacggag gtgtaaaatg aaaagattgg aacaaattat taaattagta
    72121 tcagaatatg aaaagatcga cgttaataca ttatcggaaa aattaaatgt atcgaaagta
    72181 acgattagaa aagatttaga taaattagag tcaaaaggtt tattacacag agagcatgga
    72241 tatgctgtat taaatagtgg agatgactta aatgtacgtt tgtcaattaa ttatgaaatt
    72301 aagagaaaaa ttgttcagga agcagtaaaa ttggtgtcag ataatgaaac aataatgata
    72361 gaatctggat cgacctgtgc tttacttgct gaggaaattt gcaagcaaaa aagaaatgtt
    72421 acgattgtaa caaattcgtt ttttatagca aattttgtga gagcttatga ttcatgtcgt
    72481 attattgttc ttggtggaga gtttcagaag gattcacagg ttactgtggg acctttatta
    72541 aaagaaatga tacagacttt tcatgtgcgt caagcttttg ttgggacaga tggttacgat
    72601 aaagagatgg gctttacagg aaaagattta atgcgcagtg aggtagttca atatatttca
    72661 gcagcgtcgg ataaagtcat tgtactaact gactcaagta aatttgataa aaggggtaca
    72721 gtaagaagat ttgctttaag tcaagtctat gaagtaataa cagacgaaaa actttctaaa
    72781 caaaatatag ctacattaga aaatgctggg ataatggtta aggtagtttc gtaagaggtt
    72841 aagtgtatga atcaagatag gaataaactg ctttctaaaa ttgcttatct gtattatatt
    72901 gaaaacttaa atcagtcaca aatagcagca aaattaggaa tttatagaac ctctattagt
    72961 agaatgttaa cagaagcaag gaatgtagga attgttaaaa ttgaaataga gaattttgat
    73021 accaatatgt ttaagttgga aaattatgta aaagaaaaat atggtctgga aagtttagaa
    73081 attattccaa atgaatttga tgataatcca acaattttat ctgaaagaat ttctcaagtt
    73141 gcagcaggtg tccttaggaa tctaattgat gataatatga aaattggctt ttcttggggg
    73201 aaaagtttaa gtaatttagt agatttaatt cacagtaaaa gtgtccgaaa tgttcacttc
    73261 tatcctctag caggtggtcc tagtcacata cacgctaaat accatgtgaa tacactgatt
    73321 tatgaaatgt ctagaaaatt tcatggagag tgtatattta tgaatgcaac gattgtgcaa
    73381 gaaaataaat tgttagcaga tggtattttg caatcaagat attttgaaaa tttgaaaaat
    73441 agttggaaag atttagatat agctgtagtc ggaattggtg attttagcaa taaaggaaaa
    73501 catcaatggt tagacatgct tacagaggat gactttaaag aattgaccaa agttaaaact
    73561 gtaggagaaa tttgttgtcg attttttgat tcaaaaggta aagaagtcta tgaaaactta
    73621 caggaaagaa cgatagcaat ctctttggaa gatttaaaaa atattcctca aagtttagct
    73681 gttgcttacg gtgatacgaa agtatcttcg attctttctg tcttgcgtgc taatttagta
    73741 aatcatttga ttacagacaa aaatacaatt ttaaaagttt tggaagaaga tggggatttg
    73801 acttttagag agattctagg tgagtgaaaa tgatagactg attcagttta tcgtttttct
    73861 ttttagttga ttgcacattt gtgcttatat aaacaaaaat agtttatctg ttgtttttgg
    73921 attgacaact ttattatgta gttgtattct atagttacaa aagaaaattt taaaatttca
    73981 aatgaaaaaa gctttttaca tagtgaaatg aggaggaatt tatggaaatt attgttccag
    74041 atcaaattat catgggttta attttatatg ctggcgatgc gaaacaacat atttataaag
    74101 cgttagatta cataaaaaat ggtacatgtg aacgatgtga agaagaaatc cagttagctg
    74161 atgcagcctt attagaagct cataatctac aaacaaaatt cttggcacag gaagcgtctg
    74221 gtacaaagac agaaattaca gctctctttg ttcattcaca agatcatctc atgactagta
    74281 tgacggagat taatttaatc aaagaaatta ttagtttgag aaaagaactt cataaaaaat
    74341 aatactagag tattatcatt gttattaaca tagaggagga aaacataatg gtgaagattg
    74401 gtttgttttg tgcagcaggt ttttctactg gtatgcttgt aaataatatg aaaattgcag
    74461 cgcaagctag tggagttgag gcagaaatag aggcgttttc tcagtctaaa ttagcggatt
    74521 atgcgccaaa tatagatgtt gcactattgg gtccacaagt tgcttataca ttagataaat
    74581 caaaagaaat ttgtgataag tgtgatgttc cgatagctgt tattccgatg atggactatg
    74641 gtatgttaga tgggaaaaaa gtattagatt tggccctatc tttgattagt gggtaagaaa
    74701 aggagattta ttatgtcaaa gatggatgtt cagaaaatca ttgcaccgat gatgaagttt
    74761 gtgaatatgc gtggcattat agctctaaaa gatgggatgt tagcaatttt gccattgaca
    74821 gtagttggta gtttgttctt gattatggga caattgccgt tcgaaggatt aaataagagc
    74881 attgctagtg tttttggagc taattggaca gagccgttta tgcaagtata ttcaggaact
    74941 tttgctatta tgggtctaat ttcttgtttt tcaattgcct attcttatgc taagaatagc
    75001 ggagtagagg ctttaccagc tggagttcta tctgtatctg cattctttat tttgctaaga
    75061 tcatcttata tccctaaaca aggtgaggcg attggggacg ctattagtaa agtttggttt
    75121 ggaggccagg gaattatcgg tgctatcatt ataggtttgg tagtaggaag tatttatacc
    75181 ttctttataa agagaaaaat tgttattaag atgccagaac aagttccaca agctattgcc
    75241 aaacagtttg aagcaatgat tccagcattt gtaattttct tatcttctat gattgtatat
    75301 attttagcga agtcattgac taatggcgga acattcatag aaatgattta ttctgctatt
    75361 caagttccgt tgcaaggttt aactggatct ttgtatggtg ctattggaat tgcattcttt
    75421 atatcatttt tgtggtggtt tggtgttcat gggcaatcgg tagtaaatgg agtagtgaca
    75481 gctctgcttt tatctaatct tgatgctaat aaagctatgt tagcctctgg taatctatca
    75541 ttagaaaatg gtgcacatat tgttactcaa caatttttag attcattttt aattctatca
    75601 ggttcaggga ttacgtttgg tcttgtagtt gccatgcttt ttgcagcaaa atcaaaacaa
    75661 taccaagcct taggaaaagt tgcagctttt ccagcaatat ttaacgtaaa tgagccagtt
    75721 gtatttggat ttccgattgt catgaatcca gttatgtttg tacctttcat tcttgttcct
    75781 gtacttgcag ctgtgatagt atatggagct attgcaacag gtttcatgca gccattctca
    75841 ggggtaacat tgccttggag tacaccagct attctatcag gatttttggt gggtggatgg
    75901 caaggtgttg tgactcagtt attagtattg gtgatatcta cagtggttta ctttccattc
    75961 tttaagatac aagatcgttt agcttaccaa aatgaaatca aacaatctta gaggtatttg
    76021 tgtgttactg ttaaactcac acatttgtgc taaaaattag agagttaaaa tttttctagt
    76081 taaaagcttg aaaatttcta taaaaatcgg tattatattt tcgaaagaaa taaaaatatt
    76141 t
//
LOCUS       DAVHSI010000006        63778 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.006, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000006 DAVHSI010000000
VERSION     DAVHSI010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.006"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..965)
                     /gene="pavB"
                     /locus_tag="VVR21_000419"
     CDS             complement(<1..965)
                     /gene="pavB"
                     /locus_tag="VVR21_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU6054362.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLE"
     gene            complement(1081..1491)
                     /locus_tag="VVR21_000420"
     CDS             complement(1081..1491)
                     /locus_tag="VVR21_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU6054363.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            complement(1558..2097)
                     /locus_tag="VVR21_000421"
     CDS             complement(1558..2097)
                     /locus_tag="VVR21_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6054364.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            complement(2159..2317)
                     /locus_tag="VVR21_000422"
     CDS             complement(2159..2317)
                     /locus_tag="VVR21_000422"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054365.1"
                     /translation="MKIKDQTRKLAVGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            complement(2452..3117)
                     /locus_tag="VVR21_000423"
     CDS             complement(2452..3117)
                     /locus_tag="VVR21_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU6054366.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(3131..4510)
                     /locus_tag="VVR21_000424"
     CDS             complement(3131..4510)
                     /locus_tag="VVR21_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6054367.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            4728..4880
                     /locus_tag="VVR21_000425"
     CDS             4728..4880
                     /locus_tag="VVR21_000425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054368.1"
                     /translation="MRTKASIRKLVTGCSKHCFEVANRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            complement(5120..5884)
                     /locus_tag="VVR21_000426"
     CDS             complement(5120..5884)
                     /locus_tag="VVR21_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU6054369.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            5954..6115
                     /locus_tag="VVR21_000427"
     CDS             5954..6115
                     /locus_tag="VVR21_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU6054370.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            6105..6388
                     /locus_tag="VVR21_000428"
                     /pseudo
     CDS             6105..6388
                     /locus_tag="VVR21_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            6442..6828
                     /locus_tag="VVR21_000429"
     CDS             6442..6828
                     /locus_tag="VVR21_000429"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054371.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFKVVDGTDEVSSKHCFEVVDRTDEVSNHIYGKVKLTWFEEIFEEYKSPHNKTHT
                     IKVFMYCPPKVRQKKSNFWGAVHFNT"
     gene            complement(6958..7177)
                     /locus_tag="VVR21_000430"
                     /pseudo
     CDS             complement(6958..7177)
                     /locus_tag="VVR21_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
     gene            complement(7327..8181)
                     /locus_tag="VVR21_000431"
     CDS             complement(7327..8181)
                     /locus_tag="VVR21_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6054372.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVES
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            complement(8388..9425)
                     /locus_tag="VVR21_000432"
     CDS             complement(8388..9425)
                     /locus_tag="VVR21_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU6054373.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTYGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            complement(9541..10707)
                     /locus_tag="VVR21_000433"
     CDS             complement(9541..10707)
                     /locus_tag="VVR21_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU6054374.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPVVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INEDTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            complement(10960..11364)
                     /locus_tag="VVR21_000434"
     CDS             complement(10960..11364)
                     /locus_tag="VVR21_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6054375.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            complement(11371..12186)
                     /locus_tag="VVR21_000435"
     CDS             complement(11371..12186)
                     /locus_tag="VVR21_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6054376.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            complement(12173..13078)
                     /locus_tag="VVR21_000436"
     CDS             complement(12173..13078)
                     /locus_tag="VVR21_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6054377.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            complement(13106..13582)
                     /locus_tag="VVR21_000437"
     CDS             complement(13106..13582)
                     /locus_tag="VVR21_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6054378.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            complement(13579..15366)
                     /locus_tag="VVR21_000438"
     CDS             complement(13579..15366)
                     /locus_tag="VVR21_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU6054379.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            15714..16430
                     /locus_tag="VVR21_000439"
     CDS             15714..16430
                     /locus_tag="VVR21_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6054380.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            16745..20707
                     /gene="strH"
                     /locus_tag="VVR21_000440"
     CDS             16745..20707
                     /gene="strH"
                     /locus_tag="VVR21_000440"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6054381.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETEAPKTVETETPATDKVASLPKT
                     EEKPQEEVSSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDK
                     DKPAKKDEAKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDK
                     AKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNH
                     LTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTV
                     DLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNE
                     GYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGG
                     WGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVP
                     KTEGADIPIIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNE
                     VPKDLNRYTAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEA
                     QKEEEAKREVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLR
                     FLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIG
                     LIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMD
                     FFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMA
                     FNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILG
                     QKPEDGGGFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEI
                     FELMTAFADHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRN
                     KQAELDTLVANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKK
                     ENPNLPAGQENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGSPV
                     THKGDESGLAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFY
                     SVSTSADGKEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQ
                     PAPSTAPAEESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED
                     "
     gene            complement(20762..22060)
                     /gene="purB"
                     /locus_tag="VVR21_000441"
     CDS             complement(20762..22060)
                     /gene="purB"
                     /locus_tag="VVR21_000441"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU6054382.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(22123..22350)
                     /locus_tag="VVR21_000442"
     CDS             complement(22123..22350)
                     /locus_tag="VVR21_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU6054383.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            complement(22360..23451)
                     /gene="purK"
                     /locus_tag="VVR21_000443"
     CDS             complement(22360..23451)
                     /gene="purK"
                     /locus_tag="VVR21_000443"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU6054384.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGNEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            complement(23438..23926)
                     /gene="purE"
                     /locus_tag="VVR21_000444"
     CDS             complement(23438..23926)
                     /gene="purE"
                     /locus_tag="VVR21_000444"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU6054385.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            complement(24329..25591)
                     /gene="purD"
                     /locus_tag="VVR21_000445"
     CDS             complement(24329..25591)
                     /gene="purD"
                     /locus_tag="VVR21_000445"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU6054386.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVIYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            complement(25713..27260)
                     /gene="purH"
                     /locus_tag="VVR21_000446"
     CDS             complement(25713..27260)
                     /gene="purH"
                     /locus_tag="VVR21_000446"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU6054387.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            complement(27285..27794)
                     /locus_tag="VVR21_000447"
     CDS             complement(27285..27794)
                     /locus_tag="VVR21_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6054388.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(27878..28423)
                     /gene="purN"
                     /locus_tag="VVR21_000448"
     CDS             complement(27878..28423)
                     /gene="purN"
                     /locus_tag="VVR21_000448"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU6054389.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            complement(28420..29442)
                     /locus_tag="VVR21_000449"
     CDS             complement(28420..29442)
                     /locus_tag="VVR21_000449"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU6054390.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGADPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(29479..30921)
                     /locus_tag="VVR21_000450"
     CDS             complement(29479..30921)
                     /locus_tag="VVR21_000450"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU6054391.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(31014..34739)
                     /locus_tag="VVR21_000451"
     CDS             complement(31014..34739)
                     /locus_tag="VVR21_000451"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU6054392.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELKAVKNYLLNLVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(34941..35648)
                     /locus_tag="VVR21_000452"
     CDS             complement(34941..35648)
                     /locus_tag="VVR21_000452"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU6054393.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            complement(35819..37168)
                     /locus_tag="VVR21_000453"
     CDS             complement(35819..37168)
                     /locus_tag="VVR21_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU6054394.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(37181..39334)
                     /locus_tag="VVR21_000454"
     CDS             complement(37181..39334)
                     /locus_tag="VVR21_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU6054395.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLDGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(39714..40205)
                     /locus_tag="VVR21_000455"
     CDS             complement(39714..40205)
                     /locus_tag="VVR21_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054396.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            complement(40186..40782)
                     /locus_tag="VVR21_000456"
     CDS             complement(40186..40782)
                     /locus_tag="VVR21_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6054397.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(40779..41261)
                     /locus_tag="VVR21_000457"
     CDS             complement(40779..41261)
                     /locus_tag="VVR21_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEU6054398.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(41258..42394)
                     /locus_tag="VVR21_000458"
     CDS             complement(41258..42394)
                     /locus_tag="VVR21_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054399.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
     gene            complement(42401..42697)
                     /locus_tag="VVR21_000459"
     CDS             complement(42401..42697)
                     /locus_tag="VVR21_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEU6054400.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(43240..44133)
                     /locus_tag="VVR21_000460"
     CDS             complement(43240..44133)
                     /locus_tag="VVR21_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054401.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(44884..45114)
                     /gene="blpU"
                     /locus_tag="VVR21_000461"
     CDS             complement(44884..45114)
                     /gene="blpU"
                     /locus_tag="VVR21_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU6054402.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(45317..45607)
                     /locus_tag="VVR21_000462"
                     /pseudo
     CDS             complement(45317..45607)
                     /locus_tag="VVR21_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(45653..45886)
                     /locus_tag="VVR21_000463"
     CDS             complement(45653..45886)
                     /locus_tag="VVR21_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6054403.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(45892..46884)
                     /gene="plsX"
                     /locus_tag="VVR21_000464"
     CDS             complement(45892..46884)
                     /gene="plsX"
                     /locus_tag="VVR21_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU6054404.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(46881..47651)
                     /gene="recO"
                     /locus_tag="VVR21_000465"
     CDS             complement(46881..47651)
                     /gene="recO"
                     /locus_tag="VVR21_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU6054405.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(47648..48817)
                     /locus_tag="VVR21_000466"
     CDS             complement(47648..48817)
                     /locus_tag="VVR21_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6054406.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYTPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            48966..49976
                     /locus_tag="VVR21_000467"
     CDS             48966..49976
                     /locus_tag="VVR21_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU6054407.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMSMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(50214..50651)
                     /locus_tag="VVR21_000468"
     CDS             complement(50214..50651)
                     /locus_tag="VVR21_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU6054408.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPVPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(50736..53369)
                     /gene="polA"
                     /locus_tag="VVR21_000469"
     CDS             complement(50736..53369)
                     /gene="polA"
                     /locus_tag="VVR21_000469"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU6054409.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            53625..53975
                     /locus_tag="VVR21_000470"
     CDS             53625..53975
                     /locus_tag="VVR21_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6054410.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            54190..54306
                     /locus_tag="VVR21_000471"
     CDS             54190..54306
                     /locus_tag="VVR21_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU6054411.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            54299..54532
                     /locus_tag="VVR21_000472"
     CDS             54299..54532
                     /locus_tag="VVR21_000472"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054412.1"
                     /translation="MFNQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            54659..54940
                     /locus_tag="VVR21_000473"
                     /pseudo
     CDS             54659..54940
                     /locus_tag="VVR21_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(55074..56042)
                     /locus_tag="VVR21_000474"
     CDS             complement(55074..56042)
                     /locus_tag="VVR21_000474"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6054413.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(56187..57002)
                     /locus_tag="VVR21_000475"
     CDS             complement(56187..57002)
                     /locus_tag="VVR21_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU6054414.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPD
                     STFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(57027..57524)
                     /locus_tag="VVR21_000476"
     CDS             complement(57027..57524)
                     /locus_tag="VVR21_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU6054415.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(57597..58958)
                     /gene="radA"
                     /locus_tag="VVR21_000477"
     CDS             complement(57597..58958)
                     /gene="radA"
                     /locus_tag="VVR21_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU6054416.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(58972..59487)
                     /locus_tag="VVR21_000478"
     CDS             complement(58972..59487)
                     /locus_tag="VVR21_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6054417.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(59489..59932)
                     /locus_tag="VVR21_000479"
     CDS             complement(59489..59932)
                     /locus_tag="VVR21_000479"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU6054418.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(59992..60085)
                     /gene="ffs"
                     /locus_tag="VVR21_000480"
     ncRNA           complement(59992..60085)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VVR21_000480"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(60118..60585)
                     /locus_tag="VVR21_000481"
     CDS             complement(60118..60585)
                     /locus_tag="VVR21_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU6054419.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(60786..62072)
                     /locus_tag="VVR21_000482"
     CDS             complement(60786..62072)
                     /locus_tag="VVR21_000482"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU6054420.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDSQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(62303..62539)
                     /locus_tag="VVR21_000483"
     CDS             complement(62303..62539)
                     /locus_tag="VVR21_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU6054421.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            62805..63297
                     /locus_tag="VVR21_000484"
                     /pseudo
     CDS             62805..63297
                     /locus_tag="VVR21_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(63330..63539)
                     /locus_tag="VVR21_000485"
                     /pseudo
     CDS             complement(63330..63539)
                     /locus_tag="VVR21_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(63705..63778)
                     /locus_tag="VVR21_000486"
     tRNA            complement(63705..63778)
                     /locus_tag="VVR21_000486"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(63742..63744),aa:Asn,seq:gtt)
BASE COUNT        19414 a        14761 c        11588 g        18015 t
ORIGIN      
        1 ttttctaggt aggctgctgg aacatcgata ctgtccttaa cgttgtctgc aacggctttt
       61 tgaactgttt ctttagcaac taatccattg atgttgatgt ctacattttt agtagcaact
      121 agattagtca agtcagcttt accgtcttta tttccgtaaa ctttaacagt agctttataa
      181 gtttgagtac cattagcgcg aagttgatca attaaagctt gaccttgttt accaacagta
      241 ttgccattta agtctacttc atagaagtat ttcccttttg ttaatccttc aagaggaggt
      301 aaagcaggat ttttagcagt accattgtca gaccaaggag cattatccga agcttttagt
      361 aatagacgag ttaacatacc atcaccagcg aatagttcat aaggaattac ttggtttaca
      421 ccggcagtga aaggaccttt cccttcagct ttttcaagat aagcagcagg aacatcgatg
      481 ctgtcttttg tattttcttt cactccacct tttacttgtt caggagtagt ttctgctgga
      541 cttgcttgtg tcccatccac atcagctgta tctacagttt cttttaagac atctgttagc
      601 tctggatttt tttgagcttc ttcatctttt tcaaaaagtg tatccagact agaagggctt
      661 gtttcctcgc tcacttcagt tctttctgta ggtgtcggaa gtgaattcgt atttccagta
      721 acgccctcag gtttcgcttg agtgagaacg gtgtctcctg gtttttctga taagtcaccc
      781 tctttcgttc ccgatgtctc ttcaggtaag acttgacctg gggttggatt gagcccatcg
      841 gcacgtacag aacttggctg accaactagg acaaagaagc cactagccac aacaactgag
      901 gcaacaccga cactgagacg gcgaatagac caacgagtat atctttgatt tggattgaat
      961 ttcataggat tctccttaga gtctttcttt atttgatgac tctagtataa tctcctgaaa
     1021 ttaaaaagga ctaagaaaaa gttaaaattt ttcttaaatc cctcttataa aacacttata
     1081 ttaattaaat ccataaacag atttggtgat ttgatagacg acattggaca gtttgcgatc
     1141 tggcaagaca gaatgtttgg tcaaacggct caacatggtc ttacgaatag cctgaaagac
     1201 ttctggattt ttctgctgaa tataggtcca caattggcgt ttttttgcca gatgctccgc
     1261 tgttccagat cggttgagca gggtactgga aatcaccgtc gtgagttcaa tatgattcag
     1321 cagatattct cgcattttgg gatgactcac ttgggacaaa tcaagttggt ctatcaagag
     1381 tcgattgacc ttgagttgct ggtcaatgca cttaatcatc acttgctcat tgacagactg
     1441 gtcctcacgc ccaatcaaat aacgatagaa atcgacaggc agatagtaca tggtcttgac
     1501 ctgctgaagg ggcgtaaaga caaagagatt atcgacataa aaagtatgtt caggcagtta
     1561 gaactggcta gcacgcaaca aatctgtccg ataaatcagc gagtgcatca tggtatactg
     1621 gcctttggag aaatttccga cctggtccca gccaaaaatc tgccgaacag gcaagactga
     1681 atcgtaactc atactcttct tacgagactg cccttccttt tcatagacaa aattggtcac
     1741 aaagacatcc acctcttgac ctttgctctc aagttcctgc aaggtttcaa gaattttcaa
     1801 gtaggcacga ggatccaccc agtcatcact gtcaactact ttaaaatagc gcccagaagc
     1861 ctctgccaag ccacgattga ccgcaccgcc atggcattta ttttcctgat agatggctct
     1921 aacgatatta ggatacttgc tagctaaaca ctcagcgatt tcctgagtct gatcctgaga
     1981 cccgtcattg ataatcaaaa tcccaacttg ctcaccacca atcactagcg actccacaca
     2041 gtaatgaaga taggctgctg cattatagct agaaattgcg atagacaata acttcataat
     2101 ctgctccttt aggggactga ttttttctta tactcttcga aaatctcttc aaaccgcgtc
     2161 aacgtcgcct tgccgtatag atgttactga cttcgtcagt tctatctgca acctcaaaac
     2221 agtgttttga gctgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagcagc
     2281 ccacagctag tttcctagtt tgatctttga ttttcattga gtattactct ctcttgtcac
     2341 ttctttctat tttaccataa agtccagcct ttgaagaact tttactagaa gacaaggggc
     2401 ttctgtctct atttgccatc ttaggcatca aaaaagaggg gtcatccctc tttacgaatt
     2461 caatgctact agggtatcca aatactggtt gttgatgact gccaaaatat aggtatctgc
     2521 tttcaagagg tcatctggtc caaattcaac atccaatggg gaattttcct gctctcggaa
     2581 acccaaaata ttcagattgt atttgccacg gaggtctaat ttactcagac tttgacctgc
     2641 ccaagactga ggaattttca tctccacgat agacacattt ttatccaact gaaagacatc
     2701 aacactatta tggaaaagaa tggtctgtgc tagagactgc cccatttcat actctggcga
     2761 gataaccgag tcagctccaa tcttttctag cactttctta gcggtctgac ttttgacctt
     2821 agcaataaca gtcggtaccc ccaaactctt acagtgcata accgcaagca cactcgactc
     2881 cagattttca cctgtcgcga ctacaacggt atcgcaggta tcaatccctg ctgatctcaa
     2941 taattcttca tctgtgatgt caccaatcac tccacgcgcc aaaactggct caaactgatt
     3001 gatgcgctct gcgtggtcat caatagcgat aatattcata tcctgcttgg ctagggcagc
     3061 taggacactg ctcccaaaaa ttcccaagcc caaaattcca atcgtacgat ctgacatgct
     3121 ctttcctttc ttaaccaata ctaatatctg ctttcatata gtgaatcata tctttctttt
     3181 ctggatggta atctgccaag ctaacaaaca aggtcaaggg accaattcgt cccataaaca
     3241 taagtggcat gataacactg agagccaatt tcccaaggtc aggagtcaga tttgccgtta
     3301 caccaactgt actaagagct gaaatggttt caaatatgag gtggataaag ggaggattgc
     3361 ctttggctgt tatccctagc agaatcaatc ctatcaagaa gctcatcaaa aagataataa
     3421 agacactaaa ggatttttga accgttcgcg gcgcaatcgt tcgtctcgca acattggcat
     3481 gaggcaagcc tagaagctca cttcgtgcaa agaccaagag gacaaaaaat gtcgtaatct
     3541 tgagtccccc agctgttcct ccaggtgccc cacctagaaa catctgtaag atataaatta
     3601 aaagagtcac aggatgagcc tgagtataat ctatcgtaga aaagccagct gttcgcatcg
     3661 tcactgtttg aaaaaagcta actaaaacct tatcggcaac agggagattg ccaatcgttc
     3721 cagcattgtt ccactcaaga aagagagtag ttgccgttcc aaataacaac aaacctatag
     3781 tcaacaatag tacaagcttc gtatgaaagt gcagacgtcc ttttttcttt cttcctacat
     3841 gaccagccaa atcaaaccag accataaaac caaggccgcc tgtaataatc aagcctgcaa
     3901 tcaccagatt gaccagtaaa tcggtctgaa aagcaaataa actggtgctc cctaaattat
     3961 caaaaccggc attacagaag gctgagatcg ctagaaaaat ggaactaaaa agaccacgtc
     4021 cccagccaag ttgaggaata aggcgaaaac taagcaaaat agctcctaag ctctcaacca
     4081 aaaaggtcgt gagaaaaata gaatagacaa actttctcaa agatcgagtt tctccataac
     4141 taaaactatc ctgaatagtt gcacggctac gaagactaag cttttgcttg ctctggatat
     4201 agaaaacccc aataaaggtc atgagcccta gaccaccgat ctgaatcaaa agcaaacaga
     4261 ttatttggcc ccatatatta taggtgtgag ctactggaag ggttgagaga cctgtcacac
     4321 agactgcaga gacagcagtg aaaagatgat caaaataagt cgctcgtgag ctttcaactt
     4381 ggacaaaggg caagctcaaa agaagagagc ctagtaaaat gaccaaggca aaactcaaaa
     4441 aaatacgacg ggctggcgat aaacgagata agcctagctc tattttttcc ttagataatt
     4501 tgaataacat gtttccattg taccataaaa agttcgaaat gacttagata ggataaggca
     4561 aaatctacta acaccaagcc taaaaaatgc caccttttta ttgatagctt aggcaagaac
     4621 aatacttgat agatgtgact ataggtcaaa aaagcgagac aggagctttt aacgccagct
     4681 actctatatg cttttcagga gaaaatttct ctttttgatt ataggcaatg agaaccaagg
     4741 catcaattag aaagctagtc acaggttgct caaaacactg ttttgaggtt gcaaatagaa
     4801 ctgacgaagt cagctcaaaa cactgttttg aggttgcaga tagaactgac gaagtcagta
     4861 acatctatac ggcaaggtga agctgacctg gtttgaagag attttcgaag agtatcattt
     4921 catctcactc taaatcttac caacataaaa cgcatagtat caaaattttc atcacctgat
     4981 atgatacgtt tttctgattt taaagatttt tcccaacctc aacatgccta ggacaagagg
     5041 aaggtgacct cgtttaaaca tatttttgaa aagtatgagc tagacatttt atgataaaac
     5101 aaatcctttg ccagtacaac taaaggtggt gaacacttgc taaactcagt tctagcgcct
     5161 tattaaaagc ttccgagccc cagtcacgac tgtcgtactg gtccaagtcc gctagagaat
     5221 ctgctgtgaa caacaattca ccccagagaa ccccacgcaa ttgagctact gccgcaagag
     5281 cagaacactc catctccaca acagcacagc cttcttcctt acgataagcc accttttcag
     5341 ccgtttctcg gtaaaaaccg tctgtcgtcc aggtcatgac ttcttcataa ggaatccctc
     5401 tatcatccaa aactcgctca atagcagcaa tagcctctgg ctgcatttcc atataacgac
     5461 aaggtgccac atagtggtaa ctggctccct catctcgcaa agcgcgaaca gggactagaa
     5521 aggcattttc ctctatatca gctaggacac cacaggtccc agtagagata atctgctcca
     5581 caccatagcc aatcaaccaa tccataaact gggctgctgg agcggagcca acaggagcct
     5641 gagccagaca gacctcctca cccttgtagt tgatgacata gactggatag gtcttggtag
     5701 cagaaacgaa ttcgccgaca caatccgccc ctacttccct tgcatagcgg tcaatctcct
     5761 cacctaaaaa tgcataaaca cacttctttg gcaactgcaa gtccagcccc tcgtgattgg
     5821 gcatgataac cgcctgagga ttgtcatcaa actctaaaat aggaatcgca tgtttctgaa
     5881 tcatagcctg cctcctctaa ttttgtacta ttgtatcaaa aactgacaaa gtgtcaagga
     5941 ggaagctgat gaactggaca aaaaacaagc ctacatcgtc agctgccaca gtggtttgcg
     6001 cagctatatc gcagagccta tcctcaagca agcaggattt accgcccaaa accttgacgg
     6061 cgcttattca ctatacaaaa tggttaaccc agaaggagta gaatatggaa actagtatca
     6121 gcatggctga cttttatgga aaataccaaa atgaaaatct agaacttatc gatgtccgtg
     6181 aagcacatga attccaagca ggacccaaaa atcttccata aataccttag agcaaggcta
     6241 caaagaactc aaacctgacc atgaatacta tgtcatttgt cacggaggag tccgctctgc
     6301 atctacctgc caatttctca gctcccaagg cctcaccgtt accaacgtag aaggtggtat
     6361 gaatgcttgg cccggtcaag tagaataatc aagaggagct gggcaaaaac tcaatttcag
     6421 gaaaagatga agtaatactc aatgaaaatc aaagtgcaaa ctaggaagtt agccgcaggc
     6481 tgctcaaaac actgttttaa ggttgtggat ggaactgacg aagtcagctc aaaacactgt
     6541 tttaaggttg tggatggaac tgacgaagtc agctcaaaac actgttttaa ggttgtggat
     6601 ggaactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc
     6661 agtaaccata tctacggcaa ggtgaagctg acgtggtttg aagagatttt cgaagagtat
     6721 aaatctcccc acaataaaac acatactatc aaggttttta tgtactgccc cccaaaagtt
     6781 agacagaaaa aatctaactt ttggggggca gtacatttca atacctaata ctatgcgttt
     6841 ttttaatttt aaagattttt tacaacttct tttgactcac attaaactat tctaatagtt
     6901 aatagacctt tgcacatatc gtctcaaaac attcatttat ttccgtttaa tcaagtatca
     6961 gatagccttt tctaggcgtt ccttttgagc ttcagaatca tctaggggct gattgataca
     7021 ttcagtaaga ttttcggtaa ttatcatctc aatcacgcgc tctacactag atttcactgc
     7081 tgtcagttgc gtcacgatct ccttcaatca tcttttgaat cccacgcaac tggccctctg
     7141 aacgtttcaa acgagtaata tactttgaat ttgtcatttc tttttccttg ctcgattttt
     7201 cttcattata tctctaatca gcttctttgt caaaattctc acccatccag ctcacgcagt
     7261 tctgttacca aagaccgttc aaaaagcaaa ctagcaatac ttataactta ttagaaattc
     7321 ctaattttac cttgctaaac gaatacgggt cacgatgcca tctgagtctg tgatttccaa
     7381 ttggctcgat gtcatccatt tgattggtgc gtcaacttct tgtgctcgtt gggcaatcgt
     7441 taacagttct tctttatgtg cgacttcgat gacatagtag gctaaacctg gtaagccttg
     7501 cttacgcgaa gccagacctt ttcctcccca ttcgttaact gctaaatgat gatggtaatc
     7561 tccagccgca atccaactag cgccaggcac actgaattta tcctctagtc ctaacacctt
     7621 ttgataaaac tggctggact ttcgactatc cttgacggaa agatgaatat gccccattct
     7681 cgtaccttct gccaggataa aggactctac tctttccccc aactcataaa tgtcctgcgc
     7741 cgcaagagcc tccgtcactc cgataatgcg tccatcttct cgaatatccc atgtggaaac
     7801 tggcttatct cgatagagtt caatgccatt tccctccaaa tcttccaagt aaatagcttc
     7861 actgtaacca tggtctgcac cgccgacaag aggaatttgt aaatctgtca ggtgtttcaa
     7921 gacatcagcc aaagccttgc gtgtgggcaa gagaatggcc aaatggtaaa gaccataatg
     7981 ttccctcact tctccgctct cttgtgcttg aatcagctgt accaagactt ttccaccaag
     8041 gcctagaatg gactctgtct cagtttgaga taagatttct aaaccaataa cttgctgata
     8101 aaaggctgtt tgactggcca aatcctttac atttaaaact gtctctgcca aataaatgtg
     8161 actcttgtat tcataggtca taaatggtcc tcttttctcg ttgtaattat tattgttgca
     8221 actattatat aatttccatc aagaaagtca agccagataa ctcaaaaata acaccatttc
     8281 aggataagat aaagtaaatc atttcataat aaaacgcata ttatcaaact tttcatcacc
     8341 tgacaatatg cgttatttta attttaaaga ctttttgacc agctttttta tttcacaaca
     8401 agttcataac gtgtcttact ggtgaaggtt tgaccagctt taagaatgac ttggccttta
     8461 aggtcactgt gaatggcatc tggtaaagct tgcgcttcaa gagcaatccc attgtgctgt
     8521 agcattggct gacctcctat gatgacactt tcatccacaa agtttgctgt gtagaccaca
     8581 aagcaaggag cttctgtctt gaaaagcagg aagcgacctg aattttggtc ataaaggaat
     8641 ccagcattgt catggcctgc aggaagggca aatggatgat ccaaacctga tgccagctgg
     8701 atttgctcat cttcttctgc aaagatatcc ttcaacaagg caccattgta gatgtgtttg
     8761 accacatcac ggttggcttc tggagttttg gcaggaacac cgtcaggagc gattgagtaa
     8821 atgccctctg tgtttagttg gaagacatga cggtcaatcg tctgcgtgaa atcaccagac
     8881 aagttgaaat agctgtggtt ggttggattg accagcgtat cctgatcggt cgttaccttg
     8941 tagctgattt cataggcacc agtttcttcc aagtgataac tgatccaaat cttgagattt
     9001 ccagggaacc ctcctgtccc atatgtacgc tctgtgtaga gagtcaagcc atgatcgctt
     9061 acttcttcaa cttcaaacaa gctggaatcc caaccagttg aaccactgtg attacagttg
     9121 ctagcattat taacctcaag gtcataggtc ttaccattga gctcaaaggt cgcacctgca
     9181 atacgacccg ctacaggacc tacacttgct ccatgcttgg gactattgcc tacataacta
     9241 tcaaagtcat caaatcccaa gataacattg gcaaaatttc cagccttgtc aggtgcgaca
     9301 tagcgcaaga tggtcgcacc ataagtcata acctcaagtt ggtagccacc gtctgtctca
     9361 aatcgatagg ccaagacatc ctcgccctca acatttccaa atacacgctc tgtgtatgct
     9421 ttcattctgt tctcctttta ctatttctct caagcaaaca aaccatagaa agcgtactga
     9481 caatctatgg tttatctgat aatttacaaa tcctcttgtc aagaattcat aaacactgtc
     9541 ttacttttga tattcgtgaa ttatgacacc ttgtactaca cggtttactg tacctgtagg
     9601 agacggtgta tctggtttat tttctacctt gagtgaagtc aatagggcaa agagttgggc
     9661 ataaacgatg taagggaaga cacggtaaat atcattcaag acaccgccac aaccaaggac
     9721 cacttctttg acattttcaa gaccaaaagc ttgatcactc aaaagcacaa cacgacgagc
     9781 aatctggtca ccagcaactt cacgaaccaa gtctaagtcg tacttgcgag tgtagtctgt
     9841 cgttgtacca aagaccaaga caactgtatc ttcgttgata agtgattttg gaccgtgacg
     9901 gaagccaact gggctttcat acatggtcgc aacttgacca gcagttaatt ccaaaatctt
     9961 gagctgagct tcatgagcaa gtccaaagaa aggaccagcg cctagataga tgacacggtt
    10021 aaagtctaaa tcaacgagct ctttgacatc ttctgccttg tctaaaactt tacgggcaag
    10081 actagataca acttcaaaac gttcagactt aacagcaaat tctgtaggat caaagaccaa
    10141 gagagctgtc aacatcatag acgtaaagct agaagtcatg gcaaatccag catcattaga
    10201 gacaactggt tgcaagagca agagattacg gtcatcaccg tgagcttgaa gagccaattt
    10261 accatctgct gcacaagtaa tcgtcacttg ataaagctca tccaccaagg atttggccaa
    10321 atcaacagtc gccacacttt caggcgagtt cccactacga gcaaaagaca caaggacagt
    10381 tgccacatct tttttcaaat aggttgctgg attggcaacg atatctgttg tcgcaatagc
    10441 attgaaattc catttgcgtt cgtcatagac ttccttaaaa taaggtagca aggtatctcc
    10501 cacataagca gaagtcccag cacctgtcaa gataacctta atatagtcat gtttatcagc
    10561 gatttcttgt aggaaggctg caatttcttc acgttttgct tgataaaatt caaaagcttc
    10621 tctccataca tcaggctgtt ggtagatttc acgcgtagtg atttctgcac ccaattcgag
    10681 caagtcttct tttgtataat gtagcattga gttcctcttt ttctattaaa tatgggaatg
    10741 ggagtaagct ccattcccat gtatattcta tataaaatgc tctaacgatt ttcacgttgt
    10801 cacatgaatt gaatcgagtt ccaactaaaa tctgtaggaa actagccgca ggctgctcaa
    10861 agcactgctt tgaggttgcc ggataagatt gacgaagtca gtaacatata cctacggtaa
    10921 ggcgacgttg acgtagtttg aagagatttt cgaagagtat tattcatctt cgtcatcatc
    10981 gaagcccgct aacaggtcat taactttcac aatgctttct gcagcacggc tcttgtagtc
    11041 cgcatctgcg cctgtaaggc tcgcattgat aaattcaatc accattggaa gattcatccc
    11101 tgcgtaaagg tcaatatcac gaccttccat gatcaagcga ctcaccacat tacaaggtgt
    11161 cccaccgaga agatccgcaa aaactaggaa atcatccaat ccttcaataa cagcttcaaa
    11221 tttagcagta aattcttctg ggccatcttc tggaagaaga gctactgtgt aaatgttgtc
    11281 ttgtggaccc ataatcattt ctgtgctacc cctaagctcc tcacagaagc gaccatggct
    11341 caccaaaatt aatgatttag tcataaggaa ttacattcca agtgcaaagt gaccaagggc
    11401 agaaagagcc aaagcaagta cgataataat accgatagct ttagtagagt tcataccttt
    11461 cttaccaagc aaccagaaga taaaggcagt aaagattgct ggaagcaaac gtgggaagat
    11521 ttggttcaag atgtcttgga aatcaatcat cttttcaccg attggcaact tgtaagaaat
    11581 ttcaaagtta atcactgttg ctacaagagc acccatcatg aagacaccaa gtacagatgc
    11641 agcgtcaatc aaagctgtca aggtactttg catgttgttg ataaggttaa ccccttcttt
    11701 gtaagcaaat tccaactgtt tccaacggaa gatgtcatac gctactgcaa ctgcaatcca
    11761 aaggaagatc ccccaaggtt ggccagcgat agccatagtt gctgcgactg accccatgat
    11821 agcaggtaca agtgaaccaa agattgtatc cccaagagga gcgaatggtc ccatcaaacc
    11881 tgtcttgata ccgttaacgg cgtcttttga acctacacca tctttttctt ccatggcaag
    11941 gtcaaaacca gcgataatgg tatggaagaa tggcgaagta ttgaagaatt gagtatgaac
    12001 tttcatcatt tctttcaatt caggagttcc atcaccatac attttacgca actgaggtaa
    12061 gatcatgtaa aggtaaccag aagcttgcat acgttcgtag ttccaaccta attggaaagt
    12121 aaacaagcta cgtttgttga tttgattaaa atcttctttt gtaagtttgt aattagaatt
    12181 cgtcatcttc gatttcccca ctttctgatg gtgtagaagg tgctgctaca gctacttttt
    12241 ggctattttt gaagtgaagc actgcaagga aaatacctac gatagaaata ccaatcatag
    12301 acaaaccttt gaagttgttc acgaaaccaa ttttttcagc aacttcagca ggaagagtac
    12361 ctacgatacc agcaacagcg ccaccaagac ctgttacata tgagtaaaga acagtcaaca
    12421 tagctgtcaa accaaatccc atagcaaggt agtgaaggtt acgtttaact ggaaggtaac
    12481 gaagcaagat tgcaaatcca agacctggaa gcatacgtcc tgcgagtgtc aagccatctg
    12541 caacccattt gtaggcttca acgaagtcta ctactgattg tacaaaggca ccaccaaaag
    12601 caagggcaaa gaagactgga agggcacgag atagagccca cggaatcgca ccaagcaagt
    12661 agttgcgttc aataccttta tagtcaaagc gttcgattgc agcatccaca cggtgagcga
    12721 agaaggtagt agtcatacga ccaagaacgt cgaagtaagt caagagagct gctactggta
    12781 cagcgattgt agtaatggca agcggtgcat caattccttg tgaaacagag aaggctgtcg
    12841 caagaaccgc accagaagtt gcgtcgatac gagaagcacc accgaaagta ccaaccccaa
    12901 gaacgaacag ttgcaagtta ccaccgataa gtaaaccagt agtcacatct cccatgatta
    12961 aaccagtaat gaaaccagca aatacagggg aacctgcaga tgaaacgatc gtcaactcat
    13021 cacagatttg ataagctgag tacaaagtga gaagtaaaat ttgccaccat tgtatcataa
    13081 caatgacctc ctaaaaattt ttttcctatt ttaataagct caaaaagtct gaaattggat
    13141 catttggaac catctgagca gtaagtttaa cacctttttc tgccagtttg tggaagtctt
    13201 ccacatcctt gtctactacg ttgatagaac gtgtaataga acgagtttct ggtgtttgag
    13261 acatattccc aacattaagg gtttcaagtg gtacacctgc ttctaccaaa ccaaggaagc
    13321 ggtctggttt acgagccacg ataaagagac gttggctatc gtatttacca gcaagaatat
    13381 tggctgcagc tttctcaact ggcaaaatac tcaatttcac acctggtggt gtcgcaagtt
    13441 tcaaaccact cttttcaata tcgttgttga caacttcgtc gtctacaacc ataatgcgtg
    13501 aaacatttag ttttccagcc caaagattgg ctacttgtcc gtggatcaaa cgtccatcaa
    13561 tacggcatcc tacaattgtc ataagttttc cccctttata tgttttagtg taggtttacg
    13621 agttaaatga atctcttctt tatattgacc ttctgtttca aagataatga tacggttggc
    13681 accttccttg agatagctat gagggatata aagtgagaga gttgggccaa cgttccaaaa
    13741 acgtcctaga ttctgcccat tgacaaaggc aactccctta ccaaactcag acaagtctag
    13801 gtaagtatct tttggctctt cgactgtaaa gtcataagcg taaaaggctg gttgtccttg
    13861 agtccatcct tttgaaaaat caattttctc aggattgtct agtgggagtg gatagtgttt
    13921 ccagtttagt aagaaatgca gatccttaca gacccctgtc cgaattccct tacgttgcgt
    13981 atccgctaag aacttatgcc catagttgac acgccccata ttttctatca agatatctaa
    14041 cctagatagc cctttctttt taccttgata aaaaatatct tccccaatct ctgtctgata
    14101 ttgagtttta acccactgac catcgacata cagctgggcc ctatctcgac catcaatgat
    14161 acgaagtctt tcttcttctg catcccagtt tgtttctgtt cgataaagta ggtagccata
    14221 actttgtccc agctcctcca tcttttgagg atagagactt tctacaggac ttgacaagct
    14281 atctaaggtt tcaaacaaag aaactttttc aactagtgga atagcatcca actccatact
    14341 ctctttgtag agtggttcca actgcggata ctctgaaaaa tgtgttgcca tcatcttctt
    14401 gactgcaaga tatttagcag ttggatttcc ttcttcatcc agaagggcat cgtaatcata
    14461 agatgtaact tgtggcaggt ccaaagttcc tcgagctgag caaccattca tgaaaccaaa
    14521 gtttgtacca ccgtggaaca tgtaaagatt gatagagcct tgttccaaaa cctctcgaac
    14581 tgcatctgcc aattccttag gatcccgtgt gataatcggt tctttccagc gattgaacca
    14641 accatcccag aactccatac acatgagtgg ccatttctta ccatgttcat caaagaattc
    14701 ctgcatctgc gaaaagttgt aaggtgcctt agaaccaaag tttcctgtta caaagaggtc
    14761 ctcttcaatt aaggttccag ctttcagagt agctcgccat ggaccatctg atgtaaagag
    14821 gggacaggtt acgccacact cttccattag ctgtcgaatc gctctcaggt aagccttatc
    14881 ttctccgtaa gaaccatact cattttcaac ctgcatcatg agaatattgc caccattgtt
    14941 caacaaacga ggcaccagtc ttggcaataa ctgatcatag tagcgaccaa ctgcctcgat
    15001 atatgctggg tcggatgagc gaattcgcat gttcttggtc aagagccaag ctggtaagcc
    15061 accgaattcc cattccgcac agataaatgg agacggacgc acaattgcgt agagacccaa
    15121 atcctgcgct atttggagaa atttctctaa atccagatca ccttcaaaat gaaactcacc
    15181 ttcacgaggc tcgtgtaaat tccaagcaac ataagtctct accgtattaa aaccaagagc
    15241 cttcaagtta tagagcgaat gataccaatc ctctggagga atcctaaaat aatgaatggc
    15301 accagataaa atcttaaatg attttccatc gagatagaaa tcatctcgta tctcaaatcg
    15361 tgtcataaaa ctaccttccg accgcgaaag tttgcgcttt catttgttgt tatattaatt
    15421 ataaaccaat ctgtttgaat tgtcaataga aattgtcggg atatttactg catttttact
    15481 attatacaca cattcaatta gtttcaaaca tttttagacc catttcaaac gctctttaaa
    15541 ttcggaatat aggacctaaa ataattttgt atagaatgca ttgataaaat atgagcaatc
    15601 cctatatcgc ttaatttttc aaactattat tctaattttt tattcaaaag actactattt
    15661 ttttcgcttt tatggtaaaa ttttctatgg agaaggaaaa tagaggtaaa aatatggcaa
    15721 ttcccaaata tcaatacata aaagacgaat taaaaaataa aatcatctct gggcagttta
    15781 gcagtggaga taaattttac actgaagcag aactcatttc aatgtacgat gtcagctcta
    15841 tcacagttgt tcgcgcctta aacgaccttg ccaaagatgg ctatattgtc cgccaacaag
    15901 gaaaaggaac cttcgtttca cgtgcacgca aacacaagct tgtagagttt tcagatattg
    15961 aactcttcaa tgctaaagat gataaggtaa ctgttctttc aattgaacgc ggaaacaagc
    16021 ttgtttactt ggaaaaattg ggtctacgcg gcgatcaatt ctactacaag attgaacgta
    16081 tccgcgaatc aaacggtgtc gtttatatct accatacatc ctacatccca gaacaatata
    16141 tcaacgcaaa ttatccaaac cttgaatact atagttctat ctataatcgt ttcaagttag
    16201 actaccacat tcacatgaat gatgaacact ttgaagaaat caacgaaata gtctttccaa
    16261 ctccagaaca tgcggcttca gtcctcggag tcgatgaaca attccctact gtcctacaaa
    16321 ctaaaatcac caaactcgaa tcaactggcc aagttttaga atacagtgaa acttacaaac
    16381 gatctgatta ctacaagatt aaattcatct catgtgaccg tgatcactaa gaagaaagcc
    16441 tgagcctaat cgctcgggct ttttctatgc ttattatacc acaccaaaaa ggtagcgctt
    16501 acctattttt ggaagattct ataatttgtg gaatatttta tagaaataga accaaaaatt
    16561 atactagata tatatatgta ttttttcgac caatctgaaa tcttaagttt aaattttata
    16621 tttttttata cttattatag ttttttgtca tctcctcttg actctcgtta atataagaaa
    16681 taaaataaag gcgttgattt atataatcgc tatcaatata acaatgcaat caggaggttt
    16741 tgcaatgaaa catgaaaaac aacagcgttt ttctattcgt aaatacgctg taggagcagc
    16801 ttctgttcta attggatttg ccttccaagc acagactgtt gcagccgatg gagttactcc
    16861 tactactaca gaaaaccaac cgaccatcca tacggtttct gattcccctc aatcatccga
    16921 aaatcggact gaggaaacac ctaaagcaga gcttcaacca gaagctccaa aaactgtaga
    16981 aacagaagct ccaaaaactg tagaaacaga aactccagct actgataagg tagctagtct
    17041 tccaaaaaca gaagaaaaac cacaagagga agttagttca actcctagtg ataaagcaga
    17101 ggtggtaact ccaacttctg ctgaaaaaga aactgctaat aaaaaggaag aagaagctag
    17161 ccctaaaaag gaagaagcga aagaggttga ttctaaagag tcaaatacag acaagactga
    17221 caaggataaa ccagctaaaa aagatgaagc gaaagcagag gctgacaaac cggaaacaga
    17281 gacaggaaag gaacgtgctg caactgtaaa tgaaaaacta gcgaaaaaga aaattgtttc
    17341 tattgatgct ggacgtaaat atttctcacc agaacagctc aaggaaatca tcgataaagc
    17401 gaaacattat ggctacactg atttacacct attagtcgga aatgatggac tccgtttcat
    17461 gttggacgat atgagcatca cagctaacgg caagacctat gccagtgacg atgtcaaacg
    17521 cgccattgaa aaaggtacaa atgattatta caacgatcca aacggcaatc acttaacaga
    17581 aagtcaaatg acagatctga ttaactatgc caaagataaa ggtatcggtc tcattccgac
    17641 agtaaatagt cctggacaca tggatgcgat tctcaatgcc atgaaagaat tgggaatcca
    17701 aaaccctaac tttagctatt ttgggaagaa atcagcccgt actgtcgatc ttgacaacga
    17761 acaagctgtc gcttttacaa aagcccttat cgacaagtat gctgcttatt tcgcgaaaaa
    17821 gactgaaatc ttcaacatcg gacttgatga atatgccaat gatgcgacag atgctaaagg
    17881 ttggagtgtg cttcaagctg ataaatacta tccaaacgaa ggctaccctg taaaaggcta
    17941 tgaaaaattt attgcctacg ccaatgacct cgctcgtatt gtaaaatcgc acggtctcaa
    18001 accaatggcc tttaacgacg gtatctacta caatagcgac acaagctttg gtagttttga
    18061 caaagacatc atcgtttcta tgtggactgg tggttgggga ggctacgatg tcgcttcttc
    18121 taaactacta gctgaaaaag gtcaccaaat ccttaatacc aatgatgctt ggtactacgt
    18181 tcttggacga aacgctgatg gccaaggctg gtacaatctc gatcaggggc tcaatggtat
    18241 taaaaacaca ccaatcactt ctgtaccaaa aacagaagga gctgatatcc caatcatcgg
    18301 tggtatggta gctgcttggg ctgacactcc atctgcacgt tattcaccat cacgcctctt
    18361 caaactcatg cgtcattttg caaatgccaa cgctgaatac ttcgcagctg attatgaatc
    18421 tgcagagcaa gcacttaacg aggtaccaaa agacctgaac cgttatactg cagaaagcgt
    18481 cgcggccgta aaagaagctg aaaaagctat tcgctctctc gatagcaacc ttagccgtgc
    18541 ccaacaagat acgattgatc aagccattgc taaacttcaa gaaactgtca acaacttgac
    18601 cctcacgcct gaagctcaaa aagaagaaga agctaaacgt gaggttgaaa aacttgccaa
    18661 aaacaaggta atctcaatcg atgctggacg caaatacttt actctgaacc agctcaaacg
    18721 catcgtagac aaggccagtg agctcggata ttctgatgtc catctccttc taggaaatga
    18781 cggacttcgc tttctactcg atgatatgac cattactgcc aacggaaaaa cctatgctag
    18841 tgatgacgtt aaaaaagcta ttatcgaagg aactaaagct tactacgacg atccaaacgg
    18901 tactgcacta acacaggcag aagtgacaga gctaattgaa tacgctaaat ctaaggacat
    18961 cggtctcatc ccagctatta acagtccagg tcacatggat gctatgctgg ttgccatgga
    19021 aaaattaggt attaaaaatc ctcaagccca ctttgataaa gtttcaaaaa caactatgga
    19081 cttgaaaaac gaagaagcga tgaactttgt aaaagccctc atcggtaaat acatggactt
    19141 ctttgcaggt aaaacaaaga ttttcaactt tggtactgac gaatacgcca acgatgcgac
    19201 tagtgcccaa ggctggtact acctcaagtg gtatcaactc tatggcaaat ttgccgaata
    19261 tgccaacacc ctcgcagcta tggccaaaga aagagggctt caaccaatgg ccttcaacga
    19321 tggcttctac tatgaagaca aggacgatgt tcagtttgac aaagatgtct tgatttctta
    19381 ctggtctaaa ggctggtggg gatataacct cgcatcacct caatacctag caagcaaagg
    19441 ctataaattc ttgaatacca acggtgactg gtactacatt cttggtcaaa aaccagaaga
    19501 tggtggtggt ttcctcaaga aagctattga gaatactgga aaaacaccat tcaatcaact
    19561 agcttctacc aaatatcctg aagtagatct tccaacagtc ggaagtatgc tttcaatctg
    19621 ggcagataga ccaagcgctg agtacaagga agaggaaatc tttgaactca tgactgcctt
    19681 tgcagaccac aacaaagact acttccgtgc taattataat gctctccgcg aagaattagc
    19741 taaaattcct acaaacttag aaggatatag taaagaaagt cttgaggccc ttgacgcagc
    19801 taaaacagct ctaaattaca acctcaaccg taataaacaa gctgagcttg acacacttgt
    19861 agccaaccta aaagccgctc ttcaaggcct caaaccagct gcaactcatt caggaagcct
    19921 agatgaaaat gaagtggctg ccaatgttga aaccagacca gaactcatca caagaactga
    19981 agaaattcca tttgaagtta tcaagaaaga aaatcctaac ctcccagctg gtcaggaaaa
    20041 tattatcaca gcaggagtca aaggtgaacg aactcattac atctctgtac tcactgaaaa
    20101 tggaaaaaca acagaaacag tccttgatag ccaggtaacc aaagaagtta taaaccaagt
    20161 ggttgaagtt ggctctcctg taactcacaa gggtgatgaa agtggtcttg caccaactac
    20221 tgaggtaaaa cctagactgg atatccaaga agaagaaatt ccatttacca cagtgactcg
    20281 tgaaaatcca ctcttactca aaggaaaaac acaagtcatt actaagggcg tcaatggaca
    20341 tcgtagcaac ttctactctg tgagcacttc tgccgatggt aaggaagtga aaacacttgt
    20401 aaatagtgtc gtagcacagg aagccgttac tcaaatagtc gaagtcggaa ctatggtaac
    20461 acatgtaggc gatgaaaacg gacaagccgc tattgctgaa gaaaaaccaa aactagaaat
    20521 cccaagccaa ccagctccat caactgctcc tgctgaggaa agcaaagctc ttcctcaaga
    20581 tccagctcct gtggtaacag agaaaaaact tcctgaaaca ggaactcacg attctgcagg
    20641 actagtagtc gcaggactca tgtccacact agcagcctat ggactcacta aaagaaaaga
    20701 agactaagtc ttttcgataa aaaataaaca gcgagattga agctcgctgt ttatttttta
    20761 attaatcacc tagtccaaga cgttcaaaga tatcatccac tcgtttggtg taataaactg
    20821 ggttgaagat ttcatcgatt tcttcttgag tgagacgtga tgttacttct gaatctgcct
    20881 caagaagtgg tttaaagtct acttggttgt cccaagagta ggctgttttt ggttgcacca
    20941 agtcataggc ttgctcacgg gtcatgcctt tttcaatcaa tgtcaacata gcccgttggc
    21001 taaagataag accaaaagtc gagttcatgt ttcggatcat attttctggg aagactgtca
    21061 agttcttgac gatatttcca aaacggttga gcatgtagtc aatcaaaatg gtcgtatctg
    21121 gtgtgatgat acgctcagct gatgagtgag aaatatcgcg ttcgtgccag agagcgacgt
    21181 tttcataagc cgtaatcatg tgaccacgaa tgacacgcgc cagaccagtc atattttcag
    21241 aaccgattgg gttgcgtttg tgaggcattg ctgaagaccc tttttgccct ttagcaaaga
    21301 actcttctac ttcgcgttgc tcagattttt gtagaccacg aatctcagtc gccatacgtt
    21361 cgattgaagt cgcaatgctg gcaagaaccg caaagtactc agcgtgaagg tcacgaggaa
    21421 ggacttgtgt agagatttct tgggcacgga tgccaagttt atcgcagaca tactcctcta
    21481 caaatggtgg gatattggca aagttcccaa ccgcaccaga aatcttacca gcttctacac
    21541 cagcagccgc atgctcgaag cgctcgatat tgcgtttcat ttcgctgtac caagttgcta
    21601 atttaagacc aaaggttgtc ggctcagcgt gcacaccatg agtacgcccc atcatgatgg
    21661 tgaacttgtg ctccttggcc ttgtcagcga tgatattagt gaagttttca aggtcacgac
    21721 ggatgatgtc gttggcctgc ttgtagaggt aaccataagc agtatccacc acgtcagtag
    21781 aagttaaccc atagtgaacc cacttgcgct cttcaccaag agtctcagaa accgcacgcg
    21841 tgaaagccac cacatcgtgg cgcgtctcct gctcaatttc caaaatacgg tcgatgtcaa
    21901 agtccgcctt cttgcgaatc aaagccacat cttccttagg gatttccccc aactcagccc
    21961 atgcctcgtc agagaggatt tccacctcaa gccaagcacg gtatttattt tcttcactcc
    22021 aaatattcgc catctcaggg cgagagtaac ggttgatcat gtgttaattt ttcctttctt
    22081 cttaagctgt tgggaataag ctatctaggt aaaccaagat ttctactcaa actcctcttt
    22141 tccaataaac acagacgggt aatgatctag tgtattcaaa tccgtatcca gcggtacatc
    22201 atagatagct aaataatttt cggggtattg tgcagctagt tcttcatatt tagcttgtac
    22261 cttatcttgg tcagcactgg catacaacac ttcaacaact gctccagtct tatccttttc
    22321 aataaatgta ttaacgataa tttgtatcat agacttgtcc taaaaatcaa tcccttcccc
    22381 aagctcatcc acactatccg gcacatcact aaacaaagtc acatgtccca tcttacgatt
    22441 atgctttgct tctattttac catacatgtg gaggtgggcg cttgaatttt ctgtcacata
    22501 ttgctcagca gcctcgacat gctgaccgag gacattaagc ataacggctg gcgcatggag
    22561 tttgatgact ggtaatggtg ctccgagaac acccagaata tgggtgtcaa actgagagaa
    22621 atcacaggct tcaatagaat agtgcccaga gttatgtggt cgtggggcga tttcattgac
    22681 aataacgtca tcatcagtcg caaacatttc cacacagaga gttccagaca agttgagttg
    22741 ttctgcgatt cgcactgcca tagctttagc cttgtctgct agactttcag aaatgcgggc
    22801 tggtacgatg gtcttagata ggatattgtt gcggtggata ttttcctgaa ctgggaaaaa
    22861 cgtcacctca ttgccatttc ctgacacgat gacagaaatc tcaaggtcaa agttgacaaa
    22921 ttcttccaag acgcagtctg ctgagtctgc tagcgcatag gctgcttcca agtctgcttc
    22981 tgaacgaata accttttgtc catgaccatc gtagccacca gtcgcagtct tgaggacata
    23041 gtttttcgac aagtcgatat ctgccaagtc taggctagaa gtcacgacct tgtagggtgc
    23101 cacagtgact tgagccttgt ttgacaaaaa gtccttttca aaaatacgat tttgcgaaat
    23161 gcggagcaga tctgttcctt gagggagttg tccatccttg ataacggcat ccaaaccgtc
    23221 agcgtcgaca ttttcaaact cgtaagtgag gacatcgcaa cggtctgcca actgacggag
    23281 ggcgtccaca tcgttataag gtgccacaat gatttccgcc acgcgagagg ccgggcaatc
    23341 cgccgcagga tccagcgcga taaccttgtg gcccatgtag atagcagaaa tggccatcat
    23401 ctgacccagt tgaccgccac cgataattcc gattgtttta gatgagctca tttgacgact
    23461 cctctgcgat ttttccttgt tcttcagcaa agttggcaag tgcatccgca atggacttat
    23521 cttctacaga gaggagacgg agggcaaaga gagctgcgtt agtcgctcca gcttcaccga
    23581 tagccatggt cgcaacaggc accccacccg gcatctgaac gatagaatag agtgaatcca
    23641 ctccactaag agcacgagac ttgactggca caccaatgac tggaagggtt gttttggcag
    23701 ctaccatgcc tggcaaatgc gctgcgccac cagcacctgc gatgatgatc ttgatgccac
    23761 gactacgggc ttcttctgca tgtttgaaca tgaggtctgg tgtacggtgt gcggaaacaa
    23821 ctttcttttc gtaggctaca ccgaagcggt ctaggacttc tgctgttttt tgcatggttg
    23881 cccagtcgga ttttgagccc atgatgatgg aaattactgg tttcatttct tctccttttt
    23941 cctctttttc aacaatcacc ttagcttgtg agggacggca gcagccacca aaggtgtctc
    24001 atgcctaaat tggaaaccca aggtcttcca atttccctga acgattggat tatcatccaa
    24061 tcgttctttc acaacggcgg tgattgttct atattagctc gctaacgctc gcaaaccata
    24121 cgatcattaa cgtattttgt gaatttttat ttttcttttt gataatggtc ttaggtgatg
    24181 gaggcggaag caaaccttcg gtttcattcc taaactttga gcctacggtc tccaagtttc
    24241 cccctgacca gaacattcac tgttctggtc ttttcaccac gacgaccatt atcgtgtttg
    24301 gcgactacgg cgcgttattc ttatatcttt acttaattgc cttgcttccg atatctgttc
    24361 ggtagaagag tccttctatt ttttgttggg atagttcttg gtagatgctg gcttgggctt
    24421 ctttgacggt ggctactgtg gtaaccagca tataaactcg tccgccgttt gagagcagtg
    24481 ctctgctatt ttccgcaaac ttagcccctg catagtaggt gatgacatcg ccttctgtct
    24541 tggctggcaa ctcaacgccc ctttcatagt ctagcgggta gcccttggat gcgacaacca
    24601 cacccagagt cacacccttg tccgtccaca tgatatttgg ctccttgcta tccaggatat
    24661 ctgtgatatt ttgagcaaag tcagaggtca aacgaggcaa tataatctga gtttcaggat
    24721 ctccaaatcg agagttgaac tcgatgacct tcggcccgtc tgctgtcaag ataagccctg
    24781 cgtaaatgac acctagataa gggcgacctt ctttaatcat cccttctaga actggcttga
    24841 caatggtgtc aaccgctgta tcaactacac tctgtggtaa gtgtggaact ggcgcatagg
    24901 cacccatacc acccgtgtta ggccctttgt cgccatcgta ggcacgtttg tggtcctgag
    24961 ccgttggcat gatgtagaac ttatcaccat tgacaaaggc aaagagtgaa aattcctctc
    25021 cttcaaggaa ttcctcaata accacgcgcg cacctgagtc accaaattta ttgtccaaaa
    25081 gcatctcatg agcggcttcg accgcttgct caaccgtctc agcaacgacg acacccttcc
    25141 caagcgccaa gccatccgcc ttgactacga taggcgcacc atgcttttcg atataggcct
    25201 tggcttcctc gaaatctgaa aatgtgccat aggctgctgt cgaaacacca tatttgacca
    25261 tgatttcctt ggcaaaatcc ttggaccact ccagctccgc tgcagcccta gtcggaccaa
    25321 aggccttaag cccagcttgg ttaaaatcat ccacgatacc agcagcaagg gcatcatctg
    25381 gaccgataaa ggtccaagca acatcattgg tctttgcgaa gtcaatcaat ttagaatgtt
    25441 cggaaataga gatatttacc aattccaaac catccagagt catcccatca ttcccaggag
    25501 ctacaaagac tttttccacg tcttttgatt caagtaactt tttagcaatc gcatgctcac
    25561 gaccaccaga accgacaaca agcagtttca ttcctcaacc tcttttgcga attatttacc
    25621 aacattatat caaaaaagtt cgttttaatc ttgtttcagt tagcatttta agccaaaaaa
    25681 ggaaagaaac tgttttcttc ccttttatct tcttaatgtc taaaatgtct cacacctgta
    25741 aagaccatag tcaagccgta tttatccgct gcttcgatgg attcttggtc acggacagag
    25801 ccaccgggct ggatgatggc cttaattcct gctttggcga tttcttccac gttatccgca
    25861 aatgggaaga aggcatctga agcaaggacc gccccgttca gacgatcttt ggcttggtca
    25921 atggcaaggc gaacagaagc cacacggttg gtttgacctg gaccaacacc aagtgtcatg
    25981 tggtcgttgg tcacgataat accatttgat ttgacgtact tgatagcctt ccaagcgaac
    26041 tcaagagcag tcgcttctgt ctcagttggc tgacgtttgg tcaccacttg ccagtcagct
    26101 gggctttcct tgaccacgtc ttgattttgc acgagaagtc caccgactac acctgtgtat
    26161 tctgcttcca cttcgctagc ctcttgagca ttaaatggca aggcaaggat acgcaagttt
    26221 ttctttttat tgatcaaaat agctagcgct tcatccgtat agcttggtgc aatgatgatt
    26281 tcgaggaaaa cgccgtgcat cttctcagct gtcgcagcat ccacctcacg gttgaggacg
    26341 acaatcccac caaagataga tactgggtca gactcataag cgtagtccca agcagtctcg
    26401 atgtcatcag cttgaccaat tccacatgga ttcatgtgtt tgagagccac aacggttgga
    26461 ctatctttga agtcacggat gatacggata gcagcatctg catcacggat attattaaat
    26521 gacaattctt tcccgttgag ctgtttggct gaagcaatag agtaatctgt aggcaaagct
    26581 ttctggtaaa agtccgcgtc ttgttgagga ttctcaccgt aacgcattgg ttgcttgagg
    26641 tcataagtca aagtgagttt ttcaggcttg ctttcaccca cttgagctgt gaagtattct
    26701 gcaatcaagg cgtcataagc cgctgtgtga cgaaatactt tggctgctaa acgttggcga
    26761 gtttcataag aggtttcgcc gtttgctgcc aattcgtcca aaaccacagc gtagtcagca
    26821 ggatctacca caactgtaac actggcatga tttttcgctg ctgaacgaag catagacggc
    26881 ccaccaatat cgatattttc aactgcatca gcataagtca catctggttt aaggatagtt
    26941 tccttaaatg ggtaaaggtt gaccaccaca aggtcaatga gctcaatctt gttgtcctta
    27001 gccgcttcca agtggctatc caagtcacga cgagcgagaa gccctccgtg gatatttggg
    27061 tggagggtct tcacacgacc gtccatcatt tctgggaaac cagtcacatc atcgatagca
    27121 atggtatcca ccccagcatt atcaagggca accttagttc cacctgttga gataatctcc
    27181 caaccaagtt ttttgagttc ttgggcaaat tcaacaatgc ccgctttgtc tgagacgctg
    27241 attaagacgc gtttagtcat tatattctcc tttttaatca ttagttaaac accaattaaa
    27301 tgcagtaaca gtaaaacaag ataagcaaaa ccaaggctaa gcatacctaa gatattgatc
    27361 cattttctag tctgtgattt gaacactctt ataaaaattt gataaatcag taagcctaca
    27421 cagacaccta gcgtatttaa agtcaaatcc gttatatctg ttatacctat tgctaaaata
    27481 tactgtaagc actcaaacaa taaactaatc aagaaacctg tcccgactat tcttaaacta
    27541 gataaattag tttttatcaa agggaaacaa acacctaatg gaataaagga aatcagatta
    27601 aataacattt cagcaaaaac aatttttcca tcgactatta gtggttctga aaatggaatc
    27661 caattgatat accttggagc taagaaaaat gctataaatt caggatttgt ttcaaactta
    27721 aataagattc cccaagttaa taacatcaga tagacataaa atacatatcg agttgttttt
    27781 ttagattcta acattacaaa tacctccgtt tgaagccgtc ttcaacaaac actgactcca
    27841 atttaaaatc aaagatatca tatgaatcat caaaaagtca atctgtaaat agagccttca
    27901 ctacttccgg atacaacctg tactctgctt catggatgcg agcttcaaat ctgtcaatgg
    27961 tatcatcagc tagtcgtggc acacgaacct gtttgatgac ctggcctgta tccacacccg
    28021 aatccaccca gtgaatggtc acaccagact gacccacgcc agcattccaa gcatcctcaa
    28081 tcccatgagc tcctggaaat tctggcaagt aggctggatg aatgttgaca atccgacctt
    28141 cataagccga caataaggtt ggtccaacga ttttcatgta gcctgctagg caaaccaagt
    28201 caatctggtg ttcttccaag agttcgacaa gggctgcttc gtagtctgtc ttgctctcaa
    28261 actccttgag ttcaaaagca taggacagaa cgccgagctg ctttgcacgc tcaagcacat
    28321 aggcatcacg atggtctgaa aagacaaact ccactggaaa ttcttcggca atcacctgaa
    28381 aatttgagcc attaccagag gcaaaaaccg ctattttttt catttgataa tgacactttc
    28441 gttttctttc ttgacgatgc gaccaatttc atagactgct tcatccaaca attcttttac
    28501 acgctctaca ttttcagggc tgaccgccaa cataagtccc acacccatat tgaagatttc
    28561 aaacatttct tcgtgtttaa tctgaccata tttttcaagg gctttgaaaa ttggaagcac
    28621 tggaactttg ctttcatcaa tttcagcagc taggtcatct gcaaacatac gagggacatt
    28681 ttcgataaag ccaccacctg tgatgtgggc aatgccgttg accaactctt ctttgatgag
    28741 cggcaagaca gccttgacat agatacgagt cggctcaagt agaacttcct taagtttctt
    28801 gccttccaat tctggtagga cttcctcacc tgtgtaatcc gcaaagacac gacgaaccaa
    28861 agagtaacca tttgagtgaa tcccacttga agcaagtccg agaagaacat ctccctctac
    28921 cacctttgaa ccgtcaatga tttgagattt ttcagccaca ccgaccgcaa aaccagccaa
    28981 gtcatagtcg tcttcgccgt acatgcccgg catttcagcc gtttccccac cgatgagggc
    29041 agcaccagcc tgcacacaac cttctgccac accagcaacc acttgttcta gcttagctgg
    29101 ttcattcttc cctgtcgcta cgtagtcgag aaaatagagg gggtccgcac ctgcagcaat
    29161 gatgtcgttg acacacatgg ccacacagtc ctgcccgatg gtatcgtgct tgtcgtactt
    29221 gatagccaac atgagcttgg ttccgacacc gtcagtccct gaaatcaaga cgggttcttt
    29281 aaccccagtc ttggaaaggt caaacatacc accaaagcca ccaagagctc ccatgacacc
    29341 tgcacgctcc gtacgggcca cgtgcttttt aatccgttca acaacttcat aacccgcttc
    29401 aacatccaca cccgactggg catatgcatt tttatttgtc atttgttttt tccttttctt
    29461 taatggagaa tctgtcgcct acttgtaaaa actggtcttt tcttccaaac ttctacgata
    29521 gtcttcttcg tagtcataga gaggcgttgg gtagtcaccg tcaaagtaag cgacacagag
    29581 accaccgttc ggcgcatctg tttcgatacc aatcgactca atcaagctat caattgaaag
    29641 ataagtcaga ctgtccgcac caatgatttg gcgagtttct tcgaccgtat gattggctgc
    29701 aatcagctcc tgacgggtct ggatatcaat cccgtagaaa catggatacg ctagtgcagg
    29761 acttccaatg gcaacgtgaa cctcagtcgc acccgcttct ttcaagagct gaacgatacg
    29821 acgagaggtt gttccacgta caatggaatc atccaccatg accacacgtt tgcctttgac
    29881 aacacccgaa acagcagaca gtttcatccg cactccttgc tcccgcaatt cttgagtcgg
    29941 ttggataaaa gttcgctggg tgtattggtt tttgatcaga cccatttcat ttggtaagcc
    30001 tgattcttcc gcaaatccca tagccgcgct tagggaagaa ttgggcacac caactacaat
    30061 atctgcctca tgcttaaatt ctcgcgccaa ttgcgctccc attctcttac gtgccgtatg
    30121 gacattgaca ccgtggatat tagaatcagg gcgagcaaag tagatatact ccatagaaca
    30181 aatcgccaac tgggtatcat ctgtatagct gtcatactga atgccctcgt catcaatgat
    30241 cacaatctca cctggcttca aatcacgaat ccactcggca ccaatgacct caaaagcaca
    30301 ggtttcagag gaaacaacca ccgctccgtt ggccattttc ccgatagaaa gcggacgaaa
    30361 gccattaggg tcaagagccg caatcaactt gtcctcaaac agcaagatat aggcaaaacc
    30421 acctttgaca aggctgagcg cttccttgat tttgcccatc aggctaggat tatgactgcg
    30481 acgaatgagg tgagccaaga tttcagagtc cgaagtcgcg ctgaaaattg ctcctctttg
    30541 ttccagttct ttcttgagag aggctgcatt ggtcagattt ccattatgag ccaagccaaa
    30601 ctgcatatcg tgaaaacgga agaggaaggg ctggatgtta tctacagaag cttcgccagc
    30661 agtcgcataa cgcacatgcc caatcgcacc agctcctgtc aatttatcca aattagctgg
    30721 atttctgaaa acttctgata aaagccccat gtcacgatgg cgcttcagtt gtccttgatc
    30781 gttggagagg attcctgccc cctcctgacc acggtgttga agactgtgga gtccaaaata
    30841 ggtcaactta gcagcatctg gatgtcccca aataccgaaa acaccacatt cttcattaag
    30901 agattttact tcgtatgtca ttttttatac ctaattttca tttgtaatca tcaagagcta
    30961 gatttacatg acttttacat tactgatact atctattaga aaatctgtaa gtcttatttt
    31021 ccagtgaaat gtttaaccgc tgatgcgaac aggtgttggt ctttattgcc tgggatattt
    31081 tggaaaagac catcctcata acgttctgag tggcccatct taccgatgat ttgaccattc
    31141 ttgctggtaa ttccttcgat ggcatggaca gaaccattcg gattgtactt agaatccata
    31201 cttggtttac cgttaaagtc aacgtattgg ctgaaaattt gtccattgtc acggagctct
    31261 gcaaattcct cagccgtcac gacaaacttc ccttcaccgt gcgaaacagg aatagcgtgg
    31321 atatcgccca cttgcacacc agccaaccat ggtgagttgg tattggcaat gcgagtttcc
    31381 accatcttgg ccacgtgttg gttggcatca ttgtagaaga gggttggact agtactgtta
    31441 gcatcttcaa agtttccgta tggtaggaga cccgatttga ctaaggcttg gaatccatta
    31501 caaataccga taatcaagcc accacgggcg ataaagctat caatagccac acgcactttt
    31561 tcattaagca ggatattgac gataaactta gctgaaccat ctggttcatc cgcagccgag
    31621 aatccaccgg caaagaagag aatattagtc ttgtcgatat tgtcaaccat agtttcaact
    31681 gacttgacaa tagcttcttc attcaaggtc acgaatggca ccaaattgac ctctgcacct
    31741 tctttttcga aggccttagc tgaatcatat tctgagttgg ttcctggaaa gactgggatg
    31801 taaaccacag gtttttcaac cttttctttg gctttaatca caacatctga tgccacagct
    31861 ggtacttctt ctagttcttt cgcttgggta aattctgttg ggtaaacttc ttccaatgtc
    31921 ccttgaaatg cactgtcaag cttgtgtcca tctagcttca caccgttgac agtcagtgta
    31981 aagtctgctt tcgtttgtcc aatcttctct actccagcaa tttcttcagg agatgtgaag
    32041 acaaagccgc ctaattgagc tgtcaaagct gttttaagtt caggcaaggt cacctctgca
    32101 ccaatatagt ttccaaaggt agcaagagcc aaactttcaa ctacaccacc gtatttgaca
    32161 gctgatgcag acgtcacttt atggtcagct tggcttgctt caaactgagc aaaatttttc
    32221 ttaatcaagt caaaatcaat ctctgcagag agggcttgac ctgggatgta gtagatattt
    32281 tccccaacag ctttaaattc tggagagagc accttacggc tatctgccgt cgtcacccca
    32341 aaggcaacca aggttggcgg aacggtcaat tcttcaaagg taccagacat ggagtcctta
    32401 ccaccgatag atggcaagcc aagctgaatt tgtgcttcaa tagaacctag aagagcagct
    32461 actggctgac cgaaacgctc tgcttgcttg tccatccgct cgaaatattc ttggtaagag
    32521 aaacgagcct tagaccagtt ggcaccagca gccaccaaac gagcagttgc ttcgataacc
    32581 gcataagcag caccgtggta tggagaccat tcagctacat atgggttgaa accttgagca
    32641 atgaccgacg cagtatgagt cacaccgtgt tgaactggca atttctgcac agatgcctca
    32701 gttggtgtga gttggtaacg accaccaagt gggtgattaa ccgttgagcg tccaacagag
    32761 cagtcaaaga tagtctgtaa tcctttttga cttgcatggt tgaggtcaga tagaaccgta
    32821 agggtatctg attccagtgt ttcagcagat gtttgacgct cttctgggag tttgacatcc
    32881 ttgtccacaa ctttggcatc gacaaccacg cgcacaccat tggtgtcaag gaaacgacgc
    32941 tccaagtcaa cgattgtctc accattccag tgcatgacaa gatttggttt ttcagttact
    33001 gtcgccacca caacagcatc aatattttct ttgttacatt cggcaacgaa ggtatccaca
    33061 tcttcaggac gaaccacgac cgccatccgt tcttgtgatt cagagatggc aatttctgta
    33121 ccattcaagc cctggtattt aagaggcacc ttgttgaggt cgatttcaag accgtctgcc
    33181 aattcaccga tagccacaca gacaccgcct gccccaaagt cattggactt cttgatcaga
    33241 cgagtgacat tgccattacg gaagaggcgc tgaatcttgc gttcttcgat ggcatttcct
    33301 ttttgaacct cagcaccagc agtctctaca gactcaactg tttgaacctt agaagagccc
    33361 gtcgcaccac cgacaccatc acgacctgtt ttacctccga gaaggatgat cacatcacct
    33421 gcttcaggtt tttcacggac aacattgccc ttgggagccg caccaacaac ggcaccaagt
    33481 tccatacgtt tagctacaaa gcctgggtgg aagtattcac gaacgtaggt tgtggcaagc
    33541 ccaatctggt taccatatga agaataacca tgagctgctg ttttagaaat gacttgttgt
    33601 ggcaatttcc cagcgcgagt ttccgaaatc ggtgctgtaa tatcaccagc acctgaaata
    33661 cgcatggctt ggtaaacata ggaacggcct gacaacggat cacgaatagc tccaccaata
    33721 caggtagccg ctccaccaaa tggctcaatt tctgttggat ggttgtgggt ttcgttttta
    33781 aacatgagga gccaaggttc cttgacacca tcaacgtcca cttcaatttc aactgagcag
    33841 gcattgattt cgtcagagac ttccatatca tccaatcgtc cattagcacg ctcataacga
    33901 ccgaaaatag tcgccatatc catcaaggtt tgtggttttt cagaccgacc taattcctcg
    33961 cgcatggcaa tatacttgtc ataggttgac tgcaattgct tttgaaattt agaagctgaa
    34021 aagtcgatgt gtttcaactc tgtctcaaaa gtcgtatgac ggcagtggtc agaccagtaa
    34081 gtgtccaaaa ccttaagttc agtctcagtt ggcacgcgcc cgattgactt aaagtagtct
    34141 tggataaaga gcaaatcatc cacttccatg gccatccctt gttcggcctt gtagcgagca
    34201 aaatcttctg ctgtatagct ttcaaagaaa gtcaattttg gaatggtctt gtctgactct
    34261 gaaaactcct gcttggcaat ccctgtcgtg atatccttga aacgagaatc aactagattg
    34321 agcaggtagt ttttgacagc tttcaactca gtcgcatcaa tatctttatt caccaagtaa
    34381 agttgggctg tgttgactgt cacgtcactc gaacttccca acaaaagcaa ggcttcctgt
    34441 gacgaagctg cacgctggtc aaactgccct ggcagacttt caatggcaaa gaaagcatag
    34501 ttagcaagat ccgcctgcac agatacttca tctaaaacat ggtcggttac ctgctcagag
    34561 aaaatgtgct tctctgcagg tgcaaacaag tcctcagcca agtcaaatac atcatatact
    34621 tgcacaatac gaatactttt caagcttgac agtcccaagt tgtgctggag ctctctaacc
    34681 aaactctctg acttgacctg aaaatcagcc tttttttcaa caaaaatacg tttatccatc
    34741 aattcttatt cctttatttc agctcttgca atattcccaa acagccttga ggttgttatt
    34801 ttaaaccctg caacttttcc cagacaattt cgtaaacatc tgttagttca cctagttctc
    34861 tacagagtga aaaggtctgg gggacctttt cagcctgagt ccttttagtt gagagacgaa
    34921 ggttttccgt tgcaaacaga ttatttcaat tcctgcaact tttcccaaac aatctcataa
    34981 acgtcggtta gttctcccaa tcctctacgg aaaacatcct tatccatgtg gttgccatca
    35041 gcgtcccaca agcggcagtt atctggtgaa aattcgtctg ccaagataat cttgccatcc
    35101 ttgtcaaaac cgaactctag cttaaagtca atcaatttaa gcccaatctc agcaaaccag
    35161 actttcaata gttcattgat acgacgcgtt tcttccttca agtaggcaat ctgctggtca
    35221 cccgcaatct gtaggaattt cacatgctca tcattgataa atggatcatc caaatcatca
    35281 tttttgtagt aaaattcgac aatcggagtc tccaaggcga ttccctcatc cacaccaaaa
    35341 cgttttgaaa aggaaccagc agtatagttg cggagcacga cttccaaagg aataatctta
    35401 acctttttat tgagttgttc cgtgtctgaa agtttctcca caaagtgagt cgccacacca
    35461 gccgcattta atttctcaaa aataaaagat gagatctgat tattcaagac tcccttacct
    35521 gcaatctgct ccttcttgac accgttgaaa gcagtcgcct ggtccttgta agttgaaata
    35581 ataagatttt catcctcagt tgtatagata tctttagctt ttcccgaata gatcaattgt
    35641 tttgacattt taaagttcgc ctttcgtatt acttgagcac attttaccac aaaaaaccaa
    35701 aaaacacaag aatttaaccg aataaatagc agatattttt caaaaattgt aaagaaaaaa
    35761 actgcaagaa gaatctttct cacagtttaa aaattattta actctaaaaa cacgaacatt
    35821 actctttgtt caaaaattga tccaaataat aacgtaggta acttttcttg cccgtaatca
    35881 tctgcaagcg gccttccacc ccgtacctaa gtttttcagc ctgctccgaa gttagattag
    35941 tctccgcctc gattttaaag aaattccctt tctcagtctt agtagctgtc gcatcaatac
    36001 ttgtaatagt agaatctagg aaaagttgat tcccggcatc atgagtcgta gtatagcgaa
    36061 cagaatcacc gaccttgatt cttgctacat cttttgaact tagataagct gtgagtttgg
    36121 ctttcccttc tctttccaaa gatggataaa gttgagctag tagggcacct tctgcaacca
    36181 tgctagaatc actggtctca ggattaagat gaagcacccc atcctcactc gccgtaattt
    36241 tccccttgtc taaaagattt ccctgtacct tcttacctga ctctgcctcc aagattttct
    36301 gggctagaag ggtcaattcc tgaccaacct ttgccaagtg ttgggattta agggattcca
    36361 attgactgct taaccctgac gcataggctt gctgggtacc tgaacctgca tactggacac
    36421 ggtaagtagc aagactagat tctaactgag aaatctgtgc ttcaacctgt gcaactgcct
    36481 gaaccttagt ttggggattt tcctcgccct gagacttgta ggactggtaa agagagtagg
    36541 ctagattctg accggccaag gaagcacctg tttcaatagc tgacttagct gtctggtaat
    36601 cgcgaatttt agcctctgtt tgactgatga ggttgccgat ttcggattgg gtttggctag
    36661 ctgctgcatt ctgggacgcg atggtctcat tttgttgcga tgtactagcc ctaagactgc
    36721 ctgcttgact gatgtagtcg cgaaaggtgg cttggtagcc aaacttatcc tcctctggaa
    36781 agtggttctc cccttcttgc aggctctttt gcagatactc caattgcttt ttttgatcct
    36841 ttagcatgtc caactgactg gcataggact ccgcttggac accctctgcc ccttcttggt
    36901 attgaaccaa aagatctccc ttcttaacca gcttattttc ttccaaatga ttgacaagaa
    36961 tacgattgtt gctagttgac tggatatttg caaggatacg actaggttcg acagtagctc
    37021 tagtggacaa actcatctcc ttttctgcaa cagttgcaaa gccaagtaaa aacacgagca
    37081 gaagggccat gggtacaatc acactactgg aaaaattatg gtaacgacga ttataaaact
    37141 ccgcactttc taaaaattct ggtttcatcc tctcctcttt ctagctattg accaaatggg
    37201 cgtaaaagcc accctgtgca agcaaatcag catgctttcc ttcttcgaca atcttgccct
    37261 gatccaagac aaccaccttc tctgtccgct cagcaatagt caagcggtga gcaatgaaaa
    37321 tcaaggtctt gtccaaagcc atgagattat cgacaatccg cttctctgtc aaaatatcca
    37381 aactgctagt cgcctcatcc aaaatcaaga ccggcgcatc tgtcaagaga gcacgcgcca
    37441 aagcgattct ctgacgttga ccacctgaaa tccctgcccc atccgaagtc aattctgtct
    37501 gataattcag tggcatgcgc tcgatatcct ctcgaatctc tgccaattcg accgcccgta
    37561 agatatcttc ctgtgtcgtc ccctccttgg ctcccaaaag aagattctcc aaaatcgttc
    37621 cgttaaagac atagggctgt tgaggcagat agttgatgta ctggcgcagg gcttttttat
    37681 caatctgatt gagattgaca ccatccagac taatctcccc ttgacttggg tcgtaaaaat
    37741 taaccatcat cttggccaaa gtcgtcttac ctgaccctga aatccccaca aaagccacct
    37801 tagacccttg gggaacggtt aaattgatat ccgacaagac gtctcgacca tagccatact
    37861 tgtaatgaac ctgcttgaag gtcatctctc ccttcatcaa gctcaaatcc tcaactgttt
    37921 tcttctcctc aaactcagaa gctactagat acacttcatt tagacggtta ttggcaacct
    37981 gcgctgtctg aagcttggtt tgcagattga tgatattttc caaaggattg gtaaagtaaa
    38041 ccagcaaggt attataggta atcaactgcc ccaaactcat cttgccatcc atgaccagaa
    38101 cagcccccat ccagagaatg ccgacattaa gcaagagatg ggcaaccttt ttcagagcct
    38161 tttgctgact ctctgctcga ctataggtaa aggatttctt cagataatcc acaaattcct
    38221 tgtcaatttt ttggtaacgc tgactttcac tggtcaagga cttgatagtc tcaataccgt
    38281 tgatgtcctc aatgatagaa gaagacagaa ccgcattggc ttccatggta tcccgattca
    38341 tcttttcaaa cggcttcata aaggcaaaga taatcactgt gtagatagga agcgccaata
    38401 aagtcatgaa aaagagattg gtattttgtg aaaatagaac aagggaaata atgacaaccg
    38461 ttgacacatc taggaaaatc gaaaggatgg tcgaagccag cgcatcgatg atactgttag
    38521 catctgtaaa acgagacacg atctcccctg tcctgcgtgt cgcaaagaag gacataggga
    38581 ggtgaaaaac atgcttgata taggacaaaa tcacgtcaat cgacaagcgt tgccccaaaa
    38641 caagcaagag atactcctga gcgtaagaca agatttgctg gaggatgtag acgatgacta
    38701 gcccaataga aataatccct agtgtcgaac gcatctgatc tggcacatag gtatcaatga
    38761 tagactgcag ataataagaa cccacaatgt taatcccggt taccaagagt gttgccaaaa
    38821 cgatattggc aatcaagcca cgctgcttca ctaatatagg gataaaagag agcagaccat
    38881 ttttttgttc cttataaggc ttatagtctg gactaggtgc cataaaaaga gtcactcctg
    38941 tccattcttc ctcaaaacgc tcacgtggca gtttagtcaa cttcaccccg ggatctggat
    39001 cggcaatatg aatgctatcc ttatcctgcc cagtcaccac atagtagtgg agcaatttcc
    39061 cttccttaag cacatgggca acaaaaggaa aagtcaaatc cggcaagtca aaaagcgtca
    39121 tatccgcctt aatggctcgc gtctcaaaac caatctcctc tgccaccttg accaagccca
    39181 aagccgtcgt cccatccatg gtcgtcttag ccaattctcg caagtgagcc aaaaaataat
    39241 aactaccata gtagccaaaa accatggcta atgaagctac accgcagtcc atctgatcca
    39301 cttgcggacg atagtgacgt ttcccaaatt tcatattcat ctccttttcc ctaatactca
    39361 atgaaaatca aagagcaaac taggaaacta gccgcaggct gctcaaaaca ctgttttgag
    39421 gttgtagata ggactgacga agtcagtcac atatatacgg caaggcgacg ttgacgtggt
    39481 ttgaatttga ttttcgaaga gtataaactc atctgataac aactatctta ccccaatcac
    39541 taaacaaaaa ctggacttcc ttcccaaatg agcctatctc cctcccaact gcactttttg
    39601 gataaaaaaa taggcagaac aaacgttcta cctagaaaat ataagaatta caagttaaca
    39661 aaaccgaaat gatttcatat cattattaag taaagaaaaa aattttagta tttctaaaaa
    39721 ctatttataa tagacattat agcattaaat aaaaatggta cagaaaacac tactgtcaat
    39781 cttaaatttt taaatctcgc ataatttgtt atcccaatta gtaatactgt caatacgctg
    39841 aaataggcaa actttatatc cgatggatta aataaataac aaagtaaaat gctaaaactt
    39901 aaggttatat ttttagataa aagaatatct ccaaagttcc tcttattctt atcaaaaaat
    39961 aatgtaatca gaaagagaga aaatccatat tcaataagag ttgctataaa tgtgaaaaca
    40021 acagaaatca ctgtcaatat tgtttctatt ttaattgtaa aaagattaga tagttcagat
    40081 aatttatcaa tttgttcatc taaaattccc gacttcatca gtaaatcaat aaacaaatat
    40141 aaaagaaaaa gataaataat cagattcatt aatttgtata aactattatt tgtttgaaat
    40201 ttcataaacc cgtccttcct ctattaaaat cctttgagat ttgctaatca attcttgatt
    40261 caataaatta tgagatacat atataatagt agagctttct ttcatggaaa ttaagcgttt
    40321 agcaatcata tcaatacttc ttgcatccac tgttgataaa gtctcatcaa taaaaatata
    40381 atcccaattt ttagcaaaaa ttaaggataa gcctaatttg aattttgttc cagtagatgc
    40441 tgtcatatag ttatctccga ttttattatc aaaaaaagta ttaatttgtt ctttatcctc
    40501 aaatgataga tggatttgaa aagaatcaca caacaactgc aaattttctt ctatagtaaa
    40561 tggaacaacc ccaagctgat tggtatcaag gtatagtaca tctttggaga cacaattctt
    40621 taaaccacta tcaaaagtct ctagcccagc taaaagttgt agaagggtgc tctttcctga
    40681 accattctct ccttcaactc tgtaaattcc cttatcaatc tctagtgata tatttttcaa
    40741 tatacattta tcataacttt tagattcatt ttcaattttc ataatttaat tccctctatc
    40801 aacgctgcta aaattaataa aagataagaa atgatatacc attttaaatt actttttata
    40861 taaataagta tatttttaat tcccctatcc ttcaataatc ggtataaaag atactgactc
    40921 ataccttgat accaaataaa attcggtatt tcaataagag catgaggtaa tattcctttt
    40981 attgtagcta ctattccaat catctgacca gatataccca attgtattcc taaagatagc
    41041 aaatcaaaaa gttgcaataa gggcgaaatc ggaaaacaga atagatatag caaaaaattt
    41101 gtagaatttg cctgtaaaac tgtcaatgta aattgtaatt ccagtttcgg aggtatagta
    41161 gcaaaagtct cattttttaa tataaagctt aaaagtaaac ctagtaaaaa acagactata
    41221 caaaataaca catagtaaat cagaaaacca ctttttctca tctaatgccc cctactaaaa
    41281 ttacaaatat tatcagaaaa caatataaaa ccagaaaact ccatctcaat aaactaactg
    41341 tacctttaat taaaaataga gctttcttat aatagacata ggctataaaa taattgaatg
    41401 gaatcaataa caaattcaac aaaatacttt ttatatcatt actataactt gtcaccggaa
    41461 tcaaacataa caacaatgaa aattgtaaga aagagattaa atgcgtcaac atcattagtt
    41521 gtgcattctt aaaaaagaaa ttcattttag aatgattaag agcagataat tgaagtaaag
    41581 ctagatctac cccaattgag gatttatgat tccctattat tgcctccatt aatgtaatat
    41641 atattgaggt ataaagaaat aatattggta tttttgtgtc atcaattgat aacatcgtca
    41701 tcatatacca aaatagatag gaaagaagaa tactaatcaa aataaaagaa aaagttaacc
    41761 ctttatttaa ccaacaaaaa cgaagcaata taaatagact gctacgaaat cttttttgac
    41821 tcattcgact gcttttaaaa tagaaattac tcgcatgatt atctaatatc cccatgacta
    41881 aaataaaata attgagtagt atgacataaa ttacaacttg tccttgttct atagacaata
    41941 gtcctataga taaaaataag aacaatttac ttataattga aaacaaacta ggtagaatta
    42001 aagaaataat ttgaatagct atcaaacaaa gagtaatgga taaataaaaa tatccaataa
    42061 tatctagaaa atacaaaata aataaataaa tgaatgattg taaaatttgg aaagaataat
    42121 atttcttgac aatggcaaga agatagagaa aaatatagtt tttccttata tagaaagtat
    42181 ttattttttt actttggata ggcagtttca tattataacg attcaaagta gcgtaatcta
    42241 ctaccaaaaa aagtaaaaat aatttccctt gaaaaggaag atagctttta aaatagattg
    42301 acaaacttat gataacaaaa aacaaaaggg ttatcccaat aaaattaaga taacctaaaa
    42361 tactttcaca ttctttttta gaaagtattt tcatctagtt ctaccataga gctgctttag
    42421 cagcaccttt ctttttcaat atataaagaa ctgttgctgc aatacccgaa ccaatagaac
    42481 ctactcctgt gattgcacct acaattgaaa ttactgctgt aactgtacta taagcactaa
    42541 tcaaattgac tacagtagca gcagcttttg tcgaaattcc taatgtccca gccaacatag
    42601 gaaaagaaac aacacctaag cttaaccaac taatgactgc taacattgct gaaacaataa
    42661 gaaatttatt atgaaattcc attcttttag atttcatttt agtgtactcc ttttgtatat
    42721 tatgtatgtt ttattgagag ttaattcgca catgttgtat tcctaactct cttcaaatgt
    42781 tcgtctatat tttatactac ttttattaac atatctataa taaataaatt actactacat
    42841 tttcctagat tatcaaatta cttttatatc actaagactc aataaaagat aatgtctatt
    42901 taacttttat acgattacta cctccttttt agtttacact tcctacatca taaataaaca
    42961 tactcaaccc tcacaatctc caaataactc ttctatatca ttgaaaattg agtttcatcc
    43021 tctatactaa tgtaggaaac ctattaaaac attcctttaa tccaatataa gaataccttg
    43081 ttccattaat ctctacccga tattatagat agaaccaaat tcctatactt aaaaggacaa
    43141 ataacgttcc acccataata aacctccttt ctttttgaaa acgttttctt tataggttta
    43201 gtatagcaaa aacatgaaaa aaacaacatg acttagaagt caggttgttg ggaaatctat
    43261 ctgtttttct gctaaaattc tctgaactaa tacctgatcg tctagcaatt ctgctagaga
    43321 aatcgccttt tcatagaaac tttctgcctc taaaatattc ttgtctacaa ataaagcata
    43381 ttttgccttt agcaaaaata gatgaggtcg gtaaaaaaca tgtcttgttt tagcaataat
    43441 tttctcaaat gtttgaatat atatcagact atcttctgtc tgaatttgga taaataggct
    43501 cagaagaact ttttccattt gaactaggct agccttatct tcatattctg aacatagcaa
    43561 tactttttga gctaactcct caaaatgttc tttatcttct aatcccatag cacaacaaaa
    43621 gaaatacaat tcaataatca acaaatcatt tacagaaaaa tatttctttt ttaataactg
    43681 ctggaaatat tcttccacta accctaaacc gtaggtcaca tctgaactac cataaatatc
    43741 aaaacgagct tgtgtcacat ccacaattaa ctgctcttcc tcaggcaaat tctcataata
    43801 gttttcatat atttcctcaa gtatagcttc ttttcgttcg attcttccct tatcagcgta
    43861 ggtttgagaa tgaatcagct catctttgag ttttaggaat ccttttggaa tctctataac
    43921 cttaacatcc acaatattct gtaatgatac tccaagttta tccgcaatca ataataattt
    43981 aggaagtgtt gctaaagctt gcccattttc aatacgtgct agctgacgaa tcgtcaactc
    44041 tgattcatca ccacaaatat ctatctgagt ttttccacaa gatcgcctaa tagttttgat
    44101 tttataacca atttcacgtt tcaactcatc catagtaata ctccttaagt tgattacaaa
    44161 gatttctttt tcttcctaat tcttttgtca atcatatata aaacgataag cgaaaacagc
    44221 ggtagaacaa tataactctt ttcactcatt atcagctgaa atcccagggt tgctagtatc
    44281 ttaaagatga aaatattcat caaaaataga aaaacaaata ctaaaaaata ttttaaaacc
    44341 ttcttcattt cttttcttca actttcctaa tttctacacc tattttatcg aaaatatata
    44401 taaaactcca aataaacact tcgactgcac tttttttggc aaaaaataga cagaacaaac
    44461 atcctaccta ctaaaaatat gatatgaaag gaaattgatt ttttactgtc accctaggca
    44521 agcttgaaac aaataaatca ttgatagtaa cacttacgac atcctattta ttacttcaat
    44581 ttctaatgtc tctgctattt ctaagctacc tctggtatga tctattccta gtcagaatag
    44641 ataacaccgt tctaaattac gattcatagt tactcctttt ttgactcgtt actataagac
    44701 tcctctttac atgcgcaaaa taattttgat tcagattcat catttatagt tttgattatt
    44761 ttttaacaga tttttctgtt ttcttctccg aagactttaa aaattttttt ctaattaaat
    44821 catccatata aggaccaaat ataccaacta ctaaaccaat aataaaactt ttaaaatcca
    44881 taattaccac caacatgtcg ctgcataggc cacacctcca agtatagctc ctcccgcagc
    44941 accagttgct gcaccttgcc atgttcttgt tttaattcct agctgaagac ctcgtgctgc
    45001 tcctcctcca acacctgctt tggcaaaatc tccccaattg catccgccac cttcaacgca
    45061 agcaagcatc tcagtatcca taatttcaaa ttgtgacatc gtttttgtat tcataacgaa
    45121 tacctctttt ttatttttaa tatttgtctt gttacaaact tgacaagttt agtataacag
    45181 tatctattaa tttttttcat ccaaatcttg aattggcatc gaaacgtctt gaattagctt
    45241 ttttgtttca aaatcatctc tatttttaaa aaagatgttt tctaatcact tttttactat
    45301 tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca atcaaattca
    45361 ttcgtaatcc gaagcgttta cgatgatttc gataggttgt tgaaaacatt ttaaacgttt
    45421 ttactttggc aaagatattc tcaaccttgc ttctctcctt agatagcgca tgattacagg
    45481 ctttatcttc aactgttagc ggcttgagtt tgctggattt acgtggagtt tgtgcttgag
    45541 gatatatctt catgagccct tgataaccac tgtcagccaa gattttacca gcttgtccga
    45601 tatttctcat ttctaaaaac catctacttc cgttgacttg gaactccgat tgctattttc
    45661 cttgaatgat tttaaccaca tctcctacgt tttggagttg gtcaatttct tcatcgctga
    45721 tttcgatact aaattcatct tccagagtca agataaactc catcaagtca acagaatccg
    45781 catccaaatc gtctttcaga ctcaaggatt ctgtcacgac aaagtcctct ccctgtcgct
    45841 cttggataat ggtcacaata cggtcaaaaa tttctttttc tgtcatctct tttattctcc
    45901 tgaaaattca cgcgcagtct gggcaactac gtctgtttct agcatggtac gaatctggcg
    45961 aatcgtacta taaacagcct tggcatcgct tgagccatga gtcttgacaa caggtgcctt
    46021 aacaccaaac aagaccgctc caccaacatc tgaataattg agctgttttt tcaaacctct
    46081 gaggctgtcc ttgagaagga gggcacctag tttcgctcga agaccaccac ctgtaatagc
    46141 tgtcttgagc aagcccatga ttcccatagc tgtcccttcg atggatttga gcacagcgtt
    46201 tcccgtgaaa ccatctgcca caacaacatc tgcaacgcca ttcatcaaat cacgcgcttc
    46261 cacatttccg ataaagttca aactttcatc agccactagt aattcataag tttccttacg
    46321 aagcggatcg cccttgctac tctctgttcc gttattgagc aagccaacac gtggttgcgc
    46381 aatgccacga acatttttag catagaagga tcctagaacc gcgtattgat ggaggtgctg
    46441 ggctgtattt tccgcattgg caccgaggtc tagcatgtca aatcccttcc catctacagt
    46501 cggcaaagtc gacataagcc caggacggtc gatattcttg atacgaccca cgatgaagaa
    46561 tccagcagcc aacaaggcac ctgtattccc agccgaaagg acagcgtctg cttcaccatc
    46621 tttgacagcc ttggctgcca ataccatact ggcatttttc ttattcctaa tagctctcgt
    46681 aggttcatca tccgaatcaa tcttctcatc cgtatggata atgctgacgc gctctgtcgc
    46741 tgtcagatat tgcttgattt tagcttcatc tccgtaaagt tgaacctcga tatctgaaaa
    46801 gtcagatagg gcttgattga caccctcaac aatggcctga ggtgcgtaat cgccccccat
    46861 ggcatctact gcgatttttt tcatttcttt tcctctttta gtaattgtcc ccagtctgct
    46921 agggaatcaa taaatttctt tgattttagg tgaatcccaa cgtactcttc atataattga
    46981 tccataaatt ggcgtagctc ttgcttgatt ccaggcttga gcgaaatggt ctccaaagtc
    47041 tcaaaatcaa tagcttgaaa ttgattgagc agatagggga tattgggatt gagatgacaa
    47101 cgtctcttat cctcatgata atgctctgga cagaggcagg ctccatattt gaaagaaaag
    47161 tcaaaagcct gaccaacccg atggcagaag acacactcat taaaattgag gctgattcca
    47221 aatcgagtca aaatttgaat ttcaaaaata ttggtcaaaa cctgataatc caagcctgct
    47281 tccatcaact ccaaagtctt ttgcaaaaaa gcaaacaagg gagcatcctg ctgattgtcc
    47341 tgcaaactag catctgcaag agctgccaca taggtcgcat aggccatgac aaagaggtca
    47401 ctattaatct tgggaaaagt catgacctca tgatagtctt cgatgtaact gagtccgtca
    47461 tcattgattc gcaagagaaa tcgtgccagc accaagggct gaataacagg cgccagctta
    47521 gactgaccag cgtgtttgac aaaaaacatg cgtttgccaa cctgctctgt aaaaattttg
    47581 acgagcttgt catcctcacg aaaattgcga ttgtaaagca ccaagccttg actcgtgata
    47641 gactgaatca tgcttctctc atgtactcct caagtcgttt catggcttct ttgatagtct
    47701 ccatgctggc tgcataagat aggcggacgt agccttcccc gtaacgtcca aaggctgcac
    47761 cagggataaa ggcaacggcc ttcttctgag caaaatcctt cagaaaagca aaggagtctt
    47821 gattgtagcc cgctggaatt ttagcaaaaa tatagaaggc accgtctggt ttgataatct
    47881 caaaaccaag agcagtcatt ttttcgatga tatagtcccg acgctggata tattccttct
    47941 tcatgggctc cgcatcattt ttaccagccg tcaaggcttc taccgcagca tgttgcgcca
    48001 tggtatttgc ggcagtgacc aagtattggt gactcttgat taactgggct gtgaaggccg
    48061 caggagcgaa aatcagcccc aaacgccaac ctgtcatggc atgcgattta gacaaaccat
    48121 tgataataat agcctggtct ctcaacatcg ttcctagaga cacatgggct tcgcctgtgt
    48181 aggtcaattc tgagtaaacc tcatcacaga caacaaaaat ttcgtacttg cgtaaaacag
    48241 ctgccaaggc ctctaactgc tctcgactgt aggtaattcc tgtcggattg gctggatagt
    48301 tgagaataac cgccttgagc ttatcaccct gctccaaaat ggccttctcc aacatctcag
    48361 gagtcaagac aaaaccattt tcagtcgtat caatctcaac aatttctgcc ccaactaagt
    48421 taacaatcgg ttcatagcct ggataagcag gagctggcaa aagtaccttg tcgccctctt
    48481 ccaaaatagc cgtcaaagtc gcagataaag cctctgtcgc cccaattgta accaagattt
    48541 cattttcagg agtatagtcc agttggtact tttccttaac aaagtcactg gctgcctgac
    48601 gtagagtcag cagaccactc atccctgtat agtaggattg gttctgatca atcgctcgct
    48661 tggccgcctc cttgacatgg tctggcgttg taaaatcagg ttcccccaag gtcaaacgca
    48721 agaccccagg aatctccgaa atagcctggt caaactgacg aatcaacgaa acttgaattt
    48781 tatctaactg tttattaaag cgcttagtta agtccataga tacctcctac tttcaaaacg
    48841 tatctctatt atactacaaa agccccccga ccgcaaaaat acattagaga atagctttcc
    48901 actttctatt ttacttttcc tgtttacagg tctataatgg taacagattc tatttggagg
    48961 tttttatgtc atttctatca aaaaatggag caggcatctt ggtctgcctt ctcatttcta
    49021 tcgtatcttg gtacttagga ggattcttcc ctgtgattgg cgcgcccgtt tttgcgattt
    49081 ttatgagcat gctcctacat ccctttctct cgtcttataa acaactggat gttggattga
    49141 cctttagttc caagaaattg ctccagtatg ccgttatctt gcttggtttt ggtctcaata
    49201 tctctcaagt cttcgcagtt gggcaatctt cactccctgt catcctttcc accatttcaa
    49261 tagccttgat tgttgcctac ctcttccagc gcttctttgc cctggataca aaactggcta
    49321 ccttgattgg agtaggttct tctatctgtg ggggttctgc cattgcagcg acagcgcctg
    49381 ttatccatgc taaggaaaag gaagtagccc aagccatctc cgttatcttt ttcttcaatg
    49441 tcttggctgc gctcatcttt ccaaccctcg gcacctggct tcatctatcc aatgacggct
    49501 tcgccctctt tgcaggaact gcggtcaatg atacttcctc tgtaaccgcc acagctagcg
    49561 cttgggacag tctctaccag accaataccc tcgaatccgc aaccattgtc aaactcacgc
    49621 gaaccctagc tatcatcccc atcactctct ttctttccta ctggcaaagt cgcgagcaaa
    49681 aaaataagca aggcttacaa ctgaaaaaag tcttcccact ttttatcctt cacttcatcc
    49741 ttgcatcgct cctaaccacc cttctgacct ctctcggtgt gtctagtagt ttctttaccc
    49801 ctctcaaaca actctctaaa ttcctcatta tcatggccat gagtgccatc ggtctcaaaa
    49861 ctaatctggt cgctatggtc aaatccagtg gaaaatccat tgttctcgga gccgtctgct
    49921 ggattgccat catcctcacc agccttggta tgcagaccct tatcggcatt ttctaatact
    49981 cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgcc gtaggtatat gttactgact
    50041 tcgtcagttc tatctgcaac ctcaaaacgg tgttttgagc tgacttcgtc agtcgtatct
    50101 acaacctcaa aacagtgttt tgagcagccc gcggctagtt tcctagtttg ctagtttgct
    50161 ctttgatttt cattgagtat aacacaaaag gtagcccatc agctaccttt ttcttatgct
    50221 tcctcaatca agcgagtatg ttctctcttg atacagcgat tcatcacgat atcatcacat
    50281 ccaccatcac gcaaaatctc tttcgcttct aaactttcaa gtcctagctg tgcccaaaaa
    50341 atcttggcat cagctttgag aaaatcacgc gccacatcgg gcagaaattc actgcgacga
    50401 taaacattga caatatctac aggaacagga atttcagcga ggctagcata agccttttca
    50461 cccaagattt cgccacctgc cgccttggga ttgactggga tgattttata gccccgagcc
    50521 tgcatttcct ttgttactcg attgctggtt gtttcttcac ggtcagacaa acccaccaca
    50581 gcaagggttt tactcgttgc gagatactga cgaatcacgc catcacttgg attgataaat
    50641 tcttgactca tagaaatcct cctttttcat cagtatagca cattttgaaa aggtttgcag
    50701 aattctacta caaaaaagga ggactagccc cctttttatt tagcctcgta ccaggttgcc
    50761 ccttcattct catctgcgat aagaggaaca ctgagttgaa tggcttcttc catggtttgt
    50821 ttcaccaatt tttttatctc taccaattca gatttaggca cttcaaggac gatttcatcg
    50881 tgcacttgta acagcatctt agtctgataa ccacctgcaa ccaaggcttt atccagctga
    50941 atcatggcaa tcttgagaat atctgctgcc gaaccctgga taggtgagtt gatagcagtt
    51001 cgctccgcaa aaccacgaat attgaagttg cgcgaattga tatctggcaa ctcacggcga
    51061 cgcttaaaga gggtctctac atagccctta tcacgcgcct cccgcaccac ttcatccatg
    51121 tagtttttaa tacctggaaa acgttcaaag taggtatcaa tgtaggcttt ggcttcctta
    51181 cgactaattc ccaaattatt agacaagcca aagtctgaaa tcccataaac cactccaaag
    51241 ttaactgcct tggcattgcg acggtcattt gcagtcacat tatcaggacg ctcaatgcca
    51301 aagacccgca tggctgtcga agtatggata tctgccccct cttggaaggc cttaatcaag
    51361 tgctcatcct tagaaatatg cgccaaaacg cgcaattcaa tctgtgaata atcagagctg
    51421 agtagcacac tatcctccca ctctggcaca aaagccttcc gaatcaagcg cccttgttcc
    51481 aatcgggcag gaatattttg caagtttgga tccacactag acaaacgccc ggtctgggtc
    51541 aaatcctgca catagcgagt atgaatcttt ccatcagcca aaatccagtc ctgcaagcca
    51601 attacataag tagattgaat cttagcaatt tgacggtaat ccaggatttt cttaacaatc
    51661 ggagcaatag gagcgagacg ctccaaaaca tccactgctg tcgaataacc tgtcttggtt
    51721 ttcttagtgt attctagagg aagtcccaat ttctcaaaga gaagcacgcc caactgctta
    51781 ggcgagttga cattaaactc ctcaccggcc agctcgtaaa tctcttgagt cagtttttca
    51841 atgacaagct cattttcagc ctgcatctca agcaaggtct ctttcttgac cataatccca
    51901 gcaatttcca tcttggcaag gacaaaagcc agaggttgct ccatatcata aagaagctct
    51961 aattgcccat tttcgctgag tttttcaagt aaaataggct ctgtttctac caaaacagca
    52021 agtttacaag ctaagtgttc caagaatttc tcacgttcag gaatggcctt tttaacaccc
    52081 ttaccgtaga aagtttcatc atcaaccaag taagtctgac cataaagact agcgatggtc
    52141 gcaatttcat tgtcctccac agtcgaaagg aggtatttag ccaaacggat gtcaaaagca
    52201 ggcgcctgca aatccacacc aaaacgctgc aaaagaactt taaccttctt aaagtcataa
    52261 actctcagag atgttttttc taagaaatcc ttgaaaatcg ggtcttgcaa cagctcaagc
    52321 ttgtctgtgg catagagctt atccccacaa gaccaggcaa atccaaccaa attatccgta
    52381 tggtaattct caccaaaaag ctcaaagtgg aagatagact cttcactcag catatcttga
    52441 ctgatttggt caacaatagt aaaatccaaa ccctcagcca catcagctga cgacacattt
    52501 aaagcctgct tgagctgttt gaatcccatc tcatcgtaaa atttcccaag attttcaaca
    52561 tctggaccac tatagaccaa gtcctctaaa ccaatcgcaa tcggtgcctt ggtatcaatg
    52621 gtcgctagtg ttttagacaa aaaggcctgt tccttgtcat tgatgagatt ttccttcatc
    52681 ttagaagtct tcattccatc aatattttca taaatcccct caagcgaacc atgctccagc
    52741 aagagcttaa tacccgtctt ttcaccgact ttggtcaccc cagggatatt atccgactta
    52801 tcacccatga gcgccttgag atcgataaac tgagctggtg tgaggcccat ttcttccatg
    52861 aggtaatctg gcgtaaaggc ctcaaactca gccacacctt tcttggaaat ttcaaccacc
    52921 gtatgctcat ccgtcagctg aatcaaatcc ttgtccccac tgacaatggt aatatcaaaa
    52981 ccatcctgct ctgctagctt atccagcgtc ccaatgatgt catccgcctc atactgagcc
    53041 agctcatagt gacgaatccc catatgatcc agcaactcac gaatgaaagg aaattgctca
    53101 cgaaactcat caggagtctt ggcccgacca cccttatagt ccgcatacat ctctgtccgg
    53161 aaggtcgtct ttcccgcatc aaaagccacc aaaatatgac tcggctcaac ccgctccaac
    53221 aaatgactca acatcaactg aaaaccataa atcgcattgg tatgcaaacc agccgcattc
    53281 ttaaaacggt ccaactgctg atacagcgca aaaaacgccc gaaaagctac agaagaccca
    53341 tcaatcaata ataatttttt cttatccata cacccattat aaaggaaaga atcaaaaaat
    53401 accattggga agagctagag caagtatttt tcaaactttt tccgaataaa tagatagagc
    53461 cagagaattt agtaaaccta gatttaaaaa tgtgctataa tatagtatat tgaatctata
    53521 atagtacacc ttgactgcta aaatatttct ataaattaat ttgactttcc tgatagagtt
    53581 attcacatct tatttcaact cactatagaa ggaggaatag gaggattctc agacatccgg
    53641 gcatcagccc aactaatgat ttgattgcta agaaaatatt cagcaatcca gaaatcactt
    53701 gtcaatttat tcgcgatatg ctggacttgc cagcaaaaaa tgtgaccatt ttggagggaa
    53761 gcgatattca cgtattactc tccatgcctt actcggtgca ggatttttat accagtatag
    53821 acgtcttggc ggagttggat aacggtactc aagtaattat tgagattcaa gtccatcatc
    53881 agaatttttt catcaatcac ttgtgggctt acctgtgcag tcaggttaat caaaatcttg
    53941 aaaaaattcg tcagcgagaa ggtgatactc actagagcta caaacacatc gctcctgttt
    54001 acgccattgc tatcgtggat agtaattatt tctcagatga cctggctttt catagcttta
    54061 gtatgcgcga agacacaaca ggtgaggtat tggcgattac caacaatgga caggaaaacc
    54121 atctggttaa gatggcattc ttggaattaa aaaatacaga gaaaccagca aagacaaggt
    54181 tcgcaagcca tggttggagt ttttcggcaa caagcccttt acccagcaac cgcaacgagc
    54241 cattacccaa gcaaatcaac tgctggacta caagagctgg tccgaggagg acaggaaaat
    54301 gtttaatcaa ctacatatgc gagaagaaca agtcttgtta gcacaggact atgccttgga
    54361 aactgctagg gctgaaggcc ttgaacaagg actagagcgt gggaaagttg aaggaagggc
    54421 agaaaggaaa ctttttgcct tcctagacat agtacgccaa ggtcttctga cttctgaggt
    54481 tgccagccag caattaggta tgtcagtatc tgaatttgag gcactgttgt aaaatggctc
    54541 cataatatcc atagtgggta aatcccctat ggatattatg gagcctattt tgtgtagaaa
    54601 aaaagtccca tatgacctat aatgaaaagc gacaaaacaa ctcattagaa agaatcatat
    54661 ggaacaatta cattttatca caaaattact agacattaaa gaccctaatg tccagatttt
    54721 aaacatcatc aataaggata cacacaagga aatcatcgcc aaactggact acgacgcccc
    54781 atcttgccct gagtgcggaa accaattgaa gaaatatgac tttcaaaaac cttctaaaat
    54841 tccttatctt gaaacgactg gtatacctac tagaattctc cttagaaagc gtcgattcaa
    54901 gtgctatcac tgttcaaaaa tgatggtcgc tgaaacttct gatgacgtat agtcatattt
    54961 cttctctttt tattatatca cagttttaaa tctagcttta ctagattcac cgctactatc
    55021 catttattcg gaaaaaagac gaaaaaacct gagaatcatc tcaggcttgg tcattaaatt
    55081 tttttctcaa tatcgaaaag tggagaaagt ggtcgttttt catgaatacg tacgatagca
    55141 tcccctagga gatgagcgat tgaaatctgc tcaatcttat caatcaaacg ctcttctggc
    55201 agatagatgg tatccaaaac aaccaatttc ttaatagctg atttttggat attgtccgta
    55261 gcaggaccag aaagaactgg gtgcgtacag cttgcataga cttcaacagc accagcttcc
    55321 gcaagagcat ctgccgcatg acaaatcgtt ccagcggtat caatcatatc atcaatcaag
    55381 atacaagtct tgccttcaac cttaccgatg atgttcataa cttcactagt attcatctta
    55441 tcaacgctac gacgtttatc aataatagcg atagatgttt tcaaaaattc tgccaactta
    55501 cgagcacgag tcacccctcc atggtccggg ctgacaacca catagtcaga accaaccata
    55561 ccacgacgct caaaataatc tgcaatcaga ggagcaccca tcaaatgatc cacaggaata
    55621 tcaaagaatc cttgaatttg cgcagcatgc aagtcgatgg tcaataaacg atccactcca
    55681 gctacttcaa gcatatttgc gacaagtttt gaagtgattg gctcacgcgc tctcgccttt
    55741 ctatcctgac gtgcataccc atagtaaggc atgacaacat tgacagattc tgcactcgca
    55801 cgcttcaaag catctaccat aatcaaaatt tcaagcagat tgtcatttac aggcgaacta
    55861 gttgattgta ggataaagac gtgtttccca cggattgatt cttcaatgtt gacctgaatc
    55921 tctccatctg aaaattggcg aacacttgat ttccccaact ctatcccaat ctcctgcgcc
    55981 acacgttctg ccaattcttt attagaagaa agggcaaaca gctttaaatc agaaaaagac
    56041 atgatttcct ccggtatata tgtatcgctt gtgcttttca caagattttc catctaccat
    56101 tgtagcgctt tttgcactat ttttcaatca aaaataaaag aagggcacca tatttgtacc
    56161 cttgcatcat tcttttgaaa aatattctag gtcatcaact cattgtgttt ctcaacaaag
    56221 caataagcat gataaaaacc atagagagca atagccgtaa ccactggaat cgctaaaggc
    56281 aactctgttt ccaactccac aaaaggagag ttaaacaaga agtgagttcc caaggctaaa
    56341 cctagaaaaa taaggccctg tttcttgcca accttctgtc ctttataggc tctgtaaagc
    56401 aagtaaacac ctactacagc tagacctgaa aaagtccagt gagaggcaat tcctgagatg
    56461 atacgctcta aaattcgcga aatagtaaag tcaaagccct ctggcaaatc cgtacgaata
    56521 taaccaatat cctcaatcat ttggaatccc aaaccggaag caattccaag taaaaacaaa
    56581 gattttaatt ttcgcacagg aatcaaagcc aaaacaaaaa caagtggcaa taatttcaag
    56641 ggttcttcta ccaaaggagc cacaatagca ctttcaaagg catttaaaaa tgtactatct
    56701 gggaaaagaa cccccagtaa atcatggata taagtattag caaaactaga caaccagcct
    56761 gaaaggaaca tccctcccaa taaagacaga atcaaaacct tctttggcaa ttcccatttt
    56821 ttcccaatac ggaagagaaa ataaagagcc ggaatcatgt aaaagagagc tagaaagata
    56881 gaaactccca ttagtccata ttccgcacct gacctcgaac cgtccgtata gtagatggtt
    56941 tcatactgta aaccaataca tagcaataaa ataaaaataa ataaaatact gcttttcttc
    57001 atacactttc tttctaaatg aagtatttat aattctacga ctgtcatact tcctgtatca
    57061 acattgtaaa tggcaccaga gataatgaca tcgtctggta ttaggggaga ctcgataagc
    57121 agttgcatat cctcgcgtac actctcttct atatcttgga agggcaagaa gtcctggtct
    57181 gacacatcta cacctaattc ctcttttaaa tactcctgaa aaggttcatt ttcaaaggtc
    57241 tgagcaccac agtctgtatg gtgcaatacc acaatctctc ttgtccccat ttgttgctgg
    57301 gaaataacta gcgaacgaat catgtcttca gtcactcgac cacctgcatt ccgcaagata
    57361 tgagcatccc caagtgccaa gcccagagct tgcgcaacgt gcagacgaga gtccatacag
    57421 gtcacaatag ctactcttgt tttgggttta agtggcagat ttaactgccc atgtagggca
    57481 acataagcct gattggcttg cataaactgt tcaaaatacg acacgattcc ctccttgaaa
    57541 atttgatagt caaatatttc tcctatctta tcatttttaa gagaatttgt cacggattat
    57601 gcaaagacct ttttcaagac ttcctgaatc gttgtcacgc caatgacctg aatttcctta
    57661 ggcagagtga ttcctgtcaa ggaattctta ggtacataaa tcttagtaaa gcccagttta
    57721 gcagcttcgt tgatgcgttg ctcaatacga ttcacgcgcc gaatctctcc tgtcaagccc
    57781 agttctccga caaaacattc ctgaggatta gttggcttgt ctttgtagct cgaagcaata
    57841 gcaactgcaa cagccaagtc aatcgcaggt tcatccaatt taacaccacc agcagatttg
    57901 agataggcat cctgattttg caagagaagc cctgcccgtt tttccaaaac agccataatc
    57961 aagctagcac ggttaaaatc aagtcctgtc gtagtacgct tggcatttcc aaacatggtc
    58021 ggtgttacca aagcctgaac ctccgccaaa atcggacgcg tcccttccat ggttacaacg
    58081 atggaggaac cagtcgcccc atccaaacgc tcttctagga aaacttgact cggattgagt
    58141 acctcaacca aaccgcccga ctgcatctca aaaatcccaa tctcattagt ggaaccaaaa
    58201 cgatttttga ccgctctcaa aatacgaaag gtgtggtgac gctccccttc aaagtaaagc
    58261 accgtatcca ccatatgctc caacatacga ggcccagcca aggttccttc tttggtcaca
    58321 tgacctacga taaagatggc aatgttattg gtcttggcca actgcatgag ttcagcggtc
    58381 acttcacgca cctgagaaac agacccctgc acccctgaaa tctcaggaga catgatggtc
    58441 tggatggaat caataatgag aaagtctggc tggatacgct ccacttctgc acgaacactc
    58501 tgcatattgg tctctgcata gagataaaac tcactatcaa tatcacctaa gcgctctgca
    58561 cgtagtttaa tctgctgggc agactcctcc ccactgacat agagaactgt ccccacttgg
    58621 gacaactggg ttgagacttg taggagaagg gttgatttcc caatcccagg atccccaccg
    58681 atgaggacga gacttcctgg taccactccg cctccaagca cacggttgaa ttcctccatc
    58741 tccgtcttgg ttcgattgac attgatggaa gtcacctcag ctagtttcat gggcttggtt
    58801 ttctcacctg tcaaggacac acgcgcattc ttgacctcgg caacctcaac ctcttccaca
    58861 aaagaagacc aagacccaca gttggggcaa cgtcccagat atttagggga attataccca
    58921 caattttgac atacaaatgt cgcttttttc tttgcgatga caaacctctt tctatatctc
    58981 taactcacac tcaatcactt ggcaaaaatc aatcttctca tttggcacaa actggcgcat
    59041 gagcattcga tgagcaacaa ctaccacagt ctgatgttct cgatacttag acatacattc
    59101 tagaaaccga gacttcattt ccgtagctgt ctcatattga ataggactat taggaagcaa
    59161 ctcccccttg ttttctaaaa acagtcttct agctgtttca aagttttcta ttcctgtttt
    59221 atagacctgc cattcatgta ataaaggctc tactcttaaa ggaagacccg tagcacagac
    59281 cacatacgaa gccgtttcta aagctcttgt gactgcagaa gatacgatta tttcagctga
    59341 cgagagtaaa ggatttttgc tcaatttctg gacttgctgc cgtcccatct cagacaaggg
    59401 tgccaaatct atcccaaatc ctatataaga acgctcctct aactcacggt aatctggctc
    59461 cccatgacgt acaaagataa tcttcattct agtgccctgt cgatccaaat ccaccagttc
    59521 gaacgccatc agccgcatct ccatctgcaa ttaagaaagt agcaaaaaca gcctggacaa
    59581 tacgctcccc aacttcaaga acaacctctt ggtctgtgat attcttcatc tgcgcaaaaa
    59641 tatgcccttc atttccagga tttccataat aatctccatc aatgacccca actgagttaa
    59701 ttaaaaccaa gcccttctta cgaggatttg aagaacgatc atagaggtag agaacctcag
    59761 tcggctgcat ataagcctta acccctgtcg gaaccaagac aatctctcct ggcgcaacaa
    59821 ctgtacgcac agcaaccttt aagtcgtaac cagccgcatg cgctgtctca cgcttgggca
    59881 ataaattttc atctgtaaaa ctcgaaacca attcaaaacc acgaattttc ataattttct
    59941 cttttctatt atcatttatt ctagattatt ctatcttatt tattcggaaa aagcacgaaa
    60001 aaagagcaca caattcaaat cgcttagggc tgctggattc ctcccctgac ccgcttcacg
    60061 cagaactgtt gctccactat ttattatatc acattcctat tcattttaaa agcaaaatta
    60121 ttttttccgt ctatttctaa aaaaatcctg catgatagct gcgcattcat cttccaaaat
    60181 tcctatttca acctccacac gatgattgag acgctcatct gtcaagatat cgtacaaact
    60241 cccagcagcg ccaaatttct ggtttttagc cccatagacc acatttggaa tgcgggcaag
    60301 cccaatcgcc ccactacaca tgacacaagg ttcaatggtc acaaaaagtg tgcaatccag
    60361 caagcgccag ctctcctcac tcaagttcgc atcctctata gccataattt ccgcatgcat
    60421 aaccgctcgc tgtaattcct cacgcgcatt atgcccacga ccaatgattt ccccatcttt
    60481 gacaatcaca caaccaattg gaatttcatc gtgttcaaga gcaatctcag cctctctcaa
    60541 agcctccctc ataaagactt ctttttcttc aagcgtataa tacatctctt ttctcttttc
    60601 ctacttatcg attttattat tatatcatga atcccaacac aaaaaaagcc accgaatgcg
    60661 gtgactctat agggagatta ttatgaaaaa gaaaagttta ggatatttgt tacaacaagt
    60721 taggaggtct tcttgtaact gtctatagta tacccgacct atcttaaaca aatcttaaaa
    60781 atctcttagg accaaacgct ttctaaaata tttgtttgtt cacgaccagg acctactgag
    60841 aaagtagaaa tacgaacgcc aaccaattca ctcacacgac gaacatagtt acgcgcattc
    60901 tcaggaagat cttccaaatt gcgaactccg gtaatatctt ctgaccaacc tggcaactct
    60961 tcatagatag gcttgcaacg tttcaattgc tcaagactag ctggatagta gtcaatacgt
    61021 tgactgtcaa gatcataggc cacacagatt ttcacagtat ccaaaccgct caaaacatca
    61081 atagagttca aagaaaggtt agtaatacca gaaacacgac ggctatgacg catcacaact
    61141 gagtcaaacc aacctacacg acgtggacga ccagttgttg taccatattc atgacccact
    61201 tcacggatac gttctcccac ttcatcaaac aactcagttg ggaaaggacc atctcctaca
    61261 cgactcgtat aagctttaca tacacctaca accttgtcaa tcttgcttgg accaacacca
    61321 gaaccaattg tcacaccacc agctacaggg tttgatgacg taacaaatgg ataagtacct
    61381 tggtcgatat ctagcataac accttgtgca ccttcaaaaa gcacacgttt gccattatca
    61441 agcgcatcat tcaagataac agatgtatct atcacgtatt tcttgatttg ttgaccatat
    61501 tcgtaatatt cttcaaaaat atcatcgaaa acaatcgctt tactgtcata caatttttca
    61561 aaaagacgat tcttttcagc aaggttacgt tctaaacgct cacggaaaat atctttatct
    61621 aaaagatctg caatacgaat tccaacacga gcagccttgt ccatataagc tggaccaatt
    61681 cccttaattg tcgtaccaat cttattgtcg cccttagctt cttcttgcaa gcgatccaac
    61741 tcgatatgat aaggcaaaat aacatgcgca cgatcagaaa tacgcaagtt atcagttgtt
    61801 acaccttcct catgaagata gctcaactct tttacaagag atttaggatt tacaaccata
    61861 ccattcccaa tgacagatat tttttcaggg aagaaaatcc cagatggaat caagtgcaac
    61921 ttaaatttct taccgtcaat cacaatcgtg tgaccagcat tatcaccacc ttggtaacgt
    61981 gcaatcactt ctgcattcgc tgaaaggaag tctgtaatct tccctttacc ttcatcaccc
    62041 cattgggtac ctacaacaac aactgaagtc ataattttgt ctgagccctc aggctcttcc
    62101 tttctcacat acatggcagg actctcacct gcaattatat cttacaattt attataataa
    62161 aaaatcgcct ttttatcaag aagaaacaat agaaagattt gctatttcca actattaaaa
    62221 aatgatttag aaaaattact agctatttac tattatcttt ccataaaaga gtaaattagt
    62281 tcggaaattt actaaaatta cctcaacaag aaataaaccc ccgattcatt accaattttt
    62341 caagatacaa acgataagca acacgataat ggtaaacgat aaaatcccta cgacaaccaa
    62401 tgccatatct cactaaataa taaattaaaa atttaaaatg aacatgttcc cagtcaaaat
    62461 tatcaccaaa tgtaggacca tactcttctt caatactatc atagaaatta gccatctgct
    62521 cataaatttt ttgtaacata atcaaatact ccttttcttt tttataaact tattctaaca
    62581 aaaaatttta cacattcact atcaattcct gaattgttaa aataccagcc tcaacaagat
    62641 aaaaatagga aaagttgaca aaatagaaac aaatttgcta cctaaatttc aaacaattaa
    62701 agttctaaaa agaccgcctt aaaacttttg ggtaaatcct attaaaacta taatattttt
    62761 atataggtat tatggttctg attttctagt ataaaaaaat tcaaactaga attctcctta
    62821 gaaagcgtcg attcaagtgc tatcactgtt caaaaatgat ggtcgctgaa acttctatcg
    62881 tcaagaagaa tcaccaaatc cctcgtatta tcaaccaaaa gattgctcaa aagttaattg
    62941 aaaagatttc tatgaccgac attgatcatc agttgtctat ttcaacttca actgtcattc
    63001 gcaagatcaa tgattttcac tttgagcatg atttttcgcg tcttcctgag attatgtcct
    63061 aggacgttga aacagtccgg ggagtgactg tttcaatcgg gagatggaga tgagctttat
    63121 tgctcaggac tttgataaac tcaatatcat aactgttctt gagagcagaa cacaagccat
    63181 catccgaaat cccatggata caaggctatc aagcgctact ggaaactcat tcaacaggat
    63241 agtcgtaaac tgagtgataa acatttttat cgtcctactt ttcgtatgca cttgacaaag
    63301 aaccgaaaaa tgtctcgcct ctaatatagt caattgaaac aagaacaaga caaaagagcc
    63361 tcgtaaaagg tattgcaact tggtaatacc tttttgaggt gctttttgat atgagcccat
    63421 gttttcttaa taggattgta ctcaggtgag tagggaggaa gaggtaaaag ttcatgccca
    63481 aactcctcgc ataaaagttc tagcttaccc attctatgga atcttgcatt gtccataata
    63541 tagtagattg aaactagaat agtacacctc tacttctaaa acattgttag aattcgattt
    63601 tactgtcctg atcgatttgt cctattctta tttcatttta ctataacacg aaatagatta
    63661 ttattacata acaaaaaaga ggtctaaacc tcttaactaa attactccgc cagtaggact
    63721 cgaacctacg acatcatgat taacagtcat gcgctactac caactgagct atggcgga
//
LOCUS       DAVHSI010000007        62287 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.007, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000007 DAVHSI010000000
VERSION     DAVHSI010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.007"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            196..480
                     /locus_tag="VVR21_000487"
     CDS             196..480
                     /locus_tag="VVR21_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054422.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            473..1030
                     /locus_tag="VVR21_000488"
     CDS             473..1030
                     /locus_tag="VVR21_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEU6054423.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVANMNKQPPLSLCESLYSFENLTVL
                     VVPIEYVLGMKMMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVLLEG
                     FSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(1397..3721)
                     /gene="pflB"
                     /locus_tag="VVR21_000489"
     CDS             complement(1397..3721)
                     /gene="pflB"
                     /locus_tag="VVR21_000489"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU6054424.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYKKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            4115..5176
                     /gene="dinB"
                     /locus_tag="VVR21_000490"
     CDS             4115..5176
                     /gene="dinB"
                     /locus_tag="VVR21_000490"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU6054425.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(5323..6168)
                     /locus_tag="VVR21_000491"
     CDS             complement(5323..6168)
                     /locus_tag="VVR21_000491"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU6054426.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNRTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            6424..7292
                     /locus_tag="VVR21_000492"
                     /pseudo
     CDS             6424..7292
                     /locus_tag="VVR21_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7593..9482)
                     /locus_tag="VVR21_000493"
     CDS             complement(7593..9482)
                     /locus_tag="VVR21_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU6054427.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEDDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            9620..11185
                     /locus_tag="VVR21_000494"
     CDS             9620..11185
                     /locus_tag="VVR21_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6054428.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            11185..11925
                     /locus_tag="VVR21_000495"
     CDS             11185..11925
                     /locus_tag="VVR21_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6054429.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(12034..12249)
                     /locus_tag="VVR21_000496"
     CDS             complement(12034..12249)
                     /locus_tag="VVR21_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054430.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(13120..14370)
                     /gene="ilvA"
                     /locus_tag="VVR21_000497"
     CDS             complement(13120..14370)
                     /gene="ilvA"
                     /locus_tag="VVR21_000497"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU6054431.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(14420..14776)
                     /locus_tag="VVR21_000498"
     CDS             complement(14420..14776)
                     /locus_tag="VVR21_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6054432.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(15014..15250)
                     /locus_tag="VVR21_000499"
     CDS             complement(15014..15250)
                     /locus_tag="VVR21_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054433.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(15357..16379)
                     /gene="ilvC"
                     /locus_tag="VVR21_000500"
     CDS             complement(15357..16379)
                     /gene="ilvC"
                     /locus_tag="VVR21_000500"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU6054434.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLTDVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(16445..16921)
                     /gene="ilvN"
                     /locus_tag="VVR21_000501"
     CDS             complement(16445..16921)
                     /gene="ilvN"
                     /locus_tag="VVR21_000501"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU6054435.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(16914..18614)
                     /locus_tag="VVR21_000502"
     CDS             complement(16914..18614)
                     /locus_tag="VVR21_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU6054436.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(18815..20482)
                     /locus_tag="VVR21_000503"
     CDS             complement(18815..20482)
                     /locus_tag="VVR21_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU6054437.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(20485..20850)
                     /locus_tag="VVR21_000504"
     CDS             complement(20485..20850)
                     /locus_tag="VVR21_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6054438.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(21007..21195)
                     /locus_tag="VVR21_000505"
     CDS             complement(21007..21195)
                     /locus_tag="VVR21_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU6054439.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(21311..21487)
                     /locus_tag="VVR21_000506"
     CDS             complement(21311..21487)
                     /locus_tag="VVR21_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU6054440.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(21598..21796)
                     /locus_tag="VVR21_000507"
                     /pseudo
     CDS             complement(21598..21796)
                     /locus_tag="VVR21_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(22051..23595)
                     /locus_tag="VVR21_000508"
     CDS             complement(22051..23595)
                     /locus_tag="VVR21_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU6054441.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVSGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            23808..24110
                     /gene="gatC"
                     /locus_tag="VVR21_000509"
     CDS             23808..24110
                     /gene="gatC"
                     /locus_tag="VVR21_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU6054442.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            24110..25576
                     /gene="gatA"
                     /locus_tag="VVR21_000510"
     CDS             24110..25576
                     /gene="gatA"
                     /locus_tag="VVR21_000510"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU6054443.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            25576..27018
                     /gene="gatB"
                     /locus_tag="VVR21_000511"
     CDS             25576..27018
                     /gene="gatB"
                     /locus_tag="VVR21_000511"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU6054444.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            27147..27707
                     /gene="efp"
                     /locus_tag="VVR21_000512"
     CDS             27147..27707
                     /gene="efp"
                     /locus_tag="VVR21_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU6054445.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            27729..28118
                     /locus_tag="VVR21_000513"
     CDS             27729..28118
                     /locus_tag="VVR21_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6054446.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            28111..28533
                     /gene="nusB"
                     /locus_tag="VVR21_000514"
     CDS             28111..28533
                     /gene="nusB"
                     /locus_tag="VVR21_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU6054447.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(28582..28959)
                     /locus_tag="VVR21_000515"
     CDS             complement(28582..28959)
                     /locus_tag="VVR21_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6054448.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYLMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(29322..29507)
                     /gene="briC"
                     /locus_tag="VVR21_000516"
     CDS             complement(29322..29507)
                     /gene="briC"
                     /locus_tag="VVR21_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU6054449.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(29666..30433)
                     /locus_tag="VVR21_000517"
     CDS             complement(29666..30433)
                     /locus_tag="VVR21_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU6054450.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(30430..31296)
                     /locus_tag="VVR21_000518"
     CDS             complement(30430..31296)
                     /locus_tag="VVR21_000518"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU6054451.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(31333..32700)
                     /gene="accC"
                     /locus_tag="VVR21_000519"
     CDS             complement(31333..32700)
                     /gene="accC"
                     /locus_tag="VVR21_000519"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU6054452.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(32712..33134)
                     /gene="fabZ"
                     /locus_tag="VVR21_000520"
     CDS             complement(32712..33134)
                     /gene="fabZ"
                     /locus_tag="VVR21_000520"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU6054453.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(33131..33616)
                     /locus_tag="VVR21_000521"
     CDS             complement(33131..33616)
                     /locus_tag="VVR21_000521"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU6054454.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(33619..34854)
                     /gene="fabF"
                     /locus_tag="VVR21_000522"
     CDS             complement(33619..34854)
                     /gene="fabF"
                     /locus_tag="VVR21_000522"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU6054455.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGEIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(34876..35607)
                     /gene="fabG"
                     /locus_tag="VVR21_000523"
     CDS             complement(34876..35607)
                     /gene="fabG"
                     /locus_tag="VVR21_000523"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU6054456.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(35641..36561)
                     /gene="fabD"
                     /locus_tag="VVR21_000524"
     CDS             complement(35641..36561)
                     /gene="fabD"
                     /locus_tag="VVR21_000524"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU6054457.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(36554..37528)
                     /gene="fabK"
                     /locus_tag="VVR21_000525"
     CDS             complement(36554..37528)
                     /gene="fabK"
                     /locus_tag="VVR21_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU6054458.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(37647..37871)
                     /locus_tag="VVR21_000526"
     CDS             complement(37647..37871)
                     /locus_tag="VVR21_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU6054459.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(37931..38905)
                     /locus_tag="VVR21_000527"
     CDS             complement(37931..38905)
                     /locus_tag="VVR21_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU6054460.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(38905..39339)
                     /locus_tag="VVR21_000528"
     CDS             complement(38905..39339)
                     /locus_tag="VVR21_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6054461.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(39433..40218)
                     /locus_tag="VVR21_000529"
     CDS             complement(39433..40218)
                     /locus_tag="VVR21_000529"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU6054462.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            40587..41951
                     /locus_tag="VVR21_000530"
     CDS             40587..41951
                     /locus_tag="VVR21_000530"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU6054463.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKKEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            41954..42325
                     /locus_tag="VVR21_000531"
     CDS             41954..42325
                     /locus_tag="VVR21_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU6054464.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            42539..43813
                     /gene="serS"
                     /locus_tag="VVR21_000532"
     CDS             42539..43813
                     /gene="serS"
                     /locus_tag="VVR21_000532"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU6054465.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(43838..44737)
                     /locus_tag="VVR21_000533"
     CDS             complement(43838..44737)
                     /locus_tag="VVR21_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU6054466.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKYPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TVICLTILFFVLGAYLIWLRKKV"
     gene            complement(44846..45394)
                     /locus_tag="VVR21_000534"
     CDS             complement(44846..45394)
                     /locus_tag="VVR21_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU6054467.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(45612..46934)
                     /locus_tag="VVR21_000535"
     CDS             complement(45612..46934)
                     /locus_tag="VVR21_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU6054468.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFTFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(47025..47113)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(47277..49613)
                     /locus_tag="VVR21_000536"
     CDS             complement(47277..49613)
                     /locus_tag="VVR21_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU6054469.1"
                     /translation="MNKKILETLEFDKIKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(49717..50265)
                     /locus_tag="VVR21_000537"
     CDS             complement(49717..50265)
                     /locus_tag="VVR21_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU6054470.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(50262..50564)
                     /gene="zapA"
                     /locus_tag="VVR21_000538"
     CDS             complement(50262..50564)
                     /gene="zapA"
                     /locus_tag="VVR21_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU6054471.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            50651..51532
                     /locus_tag="VVR21_000539"
     CDS             50651..51532
                     /locus_tag="VVR21_000539"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU6054472.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVATFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQITPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            51536..52150
                     /gene="lepB"
                     /locus_tag="VVR21_000540"
     CDS             51536..52150
                     /gene="lepB"
                     /locus_tag="VVR21_000540"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU6054473.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            52278..54644
                     /locus_tag="VVR21_000541"
     CDS             52278..54644
                     /locus_tag="VVR21_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU6054474.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEVPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(54692..55975)
                     /locus_tag="VVR21_000542"
     CDS             complement(54692..55975)
                     /locus_tag="VVR21_000542"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU6054475.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(56783..57919)
                     /locus_tag="VVR21_000543"
     CDS             complement(56783..57919)
                     /locus_tag="VVR21_000543"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU6054476.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQRTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIDQIVEYI"
     gene            complement(57981..58418)
                     /locus_tag="VVR21_000544"
     CDS             complement(57981..58418)
                     /locus_tag="VVR21_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6054477.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(58420..60375)
                     /locus_tag="VVR21_000545"
     CDS             complement(58420..60375)
                     /locus_tag="VVR21_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6054478.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYIKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(60399..62168)
                     /locus_tag="VVR21_000546"
     CDS             complement(60399..62168)
                     /locus_tag="VVR21_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU6054479.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGVFIACGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGSIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSADLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHINVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQQIDLNPIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        18599 a        13868 c        11639 g        18181 t
ORIGIN      
        1 tttcggataa gaaaaaaggt tcattttaca tttctaaaca ttcttttcta agatgaaaaa
       61 cagaattttt cgattgtgat ttaaagcaac aagaagattt tcagtatcat cctatagatc
      121 cgagctaatt aagaaaaact acatttttga atataaacta caataatata aactaaattt
      181 cataggagga agacaatgga ttggtacgat tatatgatac aggcatccaa acaatcacaa
      241 ttcaacgcaa gccattggtt tcgctatttg cgaaaagtta tttttgaaga ctattcttat
      301 ttaacaaacc aagatgtaga aaagttgcta gactccaaag aactaacccg ttttcaaaaa
      361 attagcttga agtatgcctt tcaagagcat actccaactc ataaatatgt gatttcatta
      421 aataaacctg ctaagttaac caatgttcaa aaattgatgg agaaatacaa acatggataa
      481 aatgaaaccg gtcttccaag ccctaaataa ggaattaatt caggaaaatc tgactttaac
      541 aattatctgt gtcgatggtt atgtcttaga atatcatggt ttacgtgcca cacaagatgt
      601 tgatgctttt tatgaccaaa atcagaaaat caatgaaatt attgctcgtg taggaaaaca
      661 gtttaatctt aacacccacg aagagttatg gctcaacaat catgttgcaa atatgaacaa
      721 acaacctccc ttaagtttat gcgaatcctt gtactcattt gagaatctga ccgttttagt
      781 agtccctatt gagtatgtgt taggaatgaa gatgatgagt atcagagagc aggatttgaa
      841 agatattggt gcaattatta aatacaaaaa ctttcattca ccattcgata cctttaaata
      901 tttaaaagac atgggatttg atactattga cctctctgtt ctattagaag gttttagtta
      961 tgcttatggt atggattggt tagaaaaatt ttttaaagaa aatcaagata aacttcgcga
     1021 attttattaa cagtatcaaa caagatgatt gtcaattagc cagtcgtctt atttttatga
     1081 tggaatgaaa taaaatcgga acaaatcact tagagaattc cagtcaattt ctagcactgt
     1141 ttgagacgtt tcagcggact atagtaaaat gaaataagaa taggacaaat cgatcaggac
     1201 agtcaaatcg atttctaaga atgttttaga agtaaaggtg tactattcta gtttcaatct
     1261 attatatttc agattcggtc cactattcct tcccaaaaac attgcatatt gcgccgaagg
     1321 aattgctcac actatcccaa gcacaaaacc ctcagtcgat tgaccgaggg ttccttttta
     1381 ttattcaaga acttgattag ctcaatgcat ccaaggcatc atccattgaa agaacttcgt
     1441 ggaagacacg ttgtgtcaat tcagtttttt gttctggagt gaggtattta gtgtttacac
     1501 agtatccaga gatacgtacg ataacgtctt cgcctgacat gatctttttg taaacatcgt
     1561 tcaagtccat aacgttcaag ttaacgtgtt gtccaccgtt ttcaaagtaa ccatcaagga
     1621 ttgttaccaa gttatcaact tgttcatcac gagtcttacc aagagcgcga ggtgatactt
     1681 gtgtagtcaa tgagataccg tcagctgcat aactaaagtc aaggctagaa agtgagttca
     1741 agttttgcaa ccaaccacct ttagctttgt tagatgggtt agcacctggt gagaagaatt
     1801 caagtttaga caagttcaca gaaccatctt cgttgaggta tacacctttg tgaactggtg
     1861 agttaccagt ttgtttagag taagcaacgt tagatgtgat tgtcaaaagt gatactgtag
     1921 cttctgcgtc tttgtatagt ttgtggctac gtagacgagt tgtgtaagct tcgatcaacc
     1981 attctgccaa ttcgtttgaa cgtgggtcat cttcacccca gcgtgggtag tcaccgattg
     2041 tttcgtaatc gtagatgtag ccatcttcat cacggattgg tttaactgta gcgtatttaa
     2101 tcgctgacaa tgtatcaaca gtgttagcaa atccacaaat accgaatccc atgttggcac
     2161 gttgtttagt tggcaagaag gccatttgaa cagcttcgta gttgtactta tcagtcatgt
     2221 agtggatgat gttcaaggca tctacgtaag tgtcagtcaa ccagtcaaga gatttttcaa
     2281 agttcgcttt aactgattcg aattcaagaa cttcgtcacg aataggatcg atgtcaaata
     2341 ctttgtagtc tttgtgaaca tcgtcgtaac caccattcaa accagtaaga agggctttaa
     2401 gaacgtttac acgagcaccg aagtactgga tgttgtggcg ttgttcttca ttttctggat
     2461 caagtggaga cacacagcat gagatacagc tcatttcacc atatccgtct ttagccattg
     2521 ttgttacacc ttcgtattgg atagaagagt gtttgtggct catgtgcata cagtagcgac
     2581 ggaaattgta cggcaatttg tcagtccaaa gaactgtcaa gtttggctct ggagagttac
     2641 cgatgttgtc aagagtgttc aagaaacggt agtccatctt agtaacacgg tgacgaccgt
     2701 cgttacccat accagccata gaagttgtga tgaatgttgg gtcacctgag tacaattggt
     2761 cataagcttt tgtacgagca aatttaactg tacgaagttt cataacgaaa tcatcaacga
     2821 attcttggat ttctgattca gtaaatgtac cacgagcaag gtcacgttct gcaaagatgt
     2881 ccaatacgat tggtacacga cctagagatg tagcagcacc gttaatcaca cggcagacag
     2941 ccatgaaagc aatgttaacc cattggattg cttctttcac gttcatcgct ggtttgcgaa
     3001 catcaacccc gtaaaggtca cccaggcgaa caacttgttg caatgcttgg tattgaaggt
     3061 ttacttcttc acgaagacgg attgtttctt catcgatttc tttgattgca ttccagtcat
     3121 ttactttttc ttgcatcaag tagtctgcac cgtaaagagc aagacgtgcg taaacaccga
     3181 tgatacgtcc gcgtgagtat gcatctggaa gaccagttac agtgtgtgcg tgacgagcgc
     3241 gacgaatatt tgaagtgtag gcacggaaaa taccgtcgtt aactgttgtt acatatttag
     3301 tgaagatttc gtgaacagct gggtctggtt cgtatccatt ttcttttaaa gtagtttcag
     3361 ccatacggat accacctttt ggcatgaagt tcaatttgaa gagttcatcg ttttggatac
     3421 cgaagataac ttcattttct ttgtcgataa atccagcagg gatatcagcg atagatgttg
     3481 gacgagtgtc cattgggaaa cgagtttctt cgtagtgtgc tttagtttct tctacaattt
     3541 tcttgatgtg aagtgaacgc tctgttggtc ctgcaaggaa gctttcgtct ccatcataag
     3601 gtgtgtagtt agcttgtaca aagcgtgata cacttgcttt ttctttccaa tctacgcctt
     3661 tgaagccttc ccaagctttg tcaaaaatat cttgtgcttc aacaactgtc ttaacaacca
     3721 tattaatgtc ctcttttttc tagtaacagt catctgttac attcataaga caagtatacc
     3781 ataaagtaac cgatttcaac aagtgcaaaa tccctatttt tacactttct tttctaaaac
     3841 agtctatatt ttatttcaaa ctgtattata tttttgaaaa aataaagtcc ttttttcttt
     3901 ttttcagaaa aaagggtata ataaaagaaa ataagcagta acactcaatg gaaatcgaaa
     3961 agcaaactag gaagctagcc gcaggctgct caaagcactg ctttgaggtt gtaaatagaa
     4021 ctgacgaagt cagctcaaaa tactgttttg aggttgcaga tggaagctga cgtggtttga
     4081 agagattttc gaaaagtata aaaaggtgct aggcatgttg atttttcctt tgctaaatga
     4141 tttgtcaaga aaaatcatcc atattgacat ggatgccttt tttgctgcgg tggaaatcaa
     4201 ggataatcct aaactcagag gaaaacctgt cattattgga agcgaccctc ggcaaacagg
     4261 tggacgggga gtcgtttcta cctgtagcta tgaggctcga gcttttggtg tccattctgc
     4321 catgagttcc aaggaagctt atgaacgttg tccccaggcc gtctttatct cagggaatta
     4381 tgagaaatac aaagctgtgg gactccagat tcgagctatt tttaagcgct atacagattt
     4441 gattgaaccc atgagcattg acgaagccta tttggatgtg acagaaaata aactcggtat
     4501 caagtcagcg gtcaaaattg ctcgcctcat tcaaaaagat atctggcaag aactccatct
     4561 aactgcttcc gcaggcgttt cttacaacaa attcttagct aaaatggcga gtgattatca
     4621 aaaaccacat ggtttgacag tgattctacc tgaacaggct gaggattttc tcaaacaaat
     4681 ggatatttcc aaatttcatg gagtaggaaa aaagacagta gaacgtcttc atcaaatggg
     4741 cgtttttact ggtgctgatt tacttgaagt tcctgaggtg accctaatag accgttttgg
     4801 tagactaggc tatgatctgt atcgaaaggc tcgtggcatt cacaactctc cagtcaaatc
     4861 caatcgcatc cgtaaatcaa tcggcaagga gaaaacctac gggaagattc tccgtgctga
     4921 ggaagatatc aaaaaagagc tgactcttct atcagaaaaa gtcgctctca atctacatca
     4981 acaagaaaaa gctggaaaaa ttgtcatttt gaaaatccgc tacgaggact tttcaactct
     5041 taccaaacga aaaagtcttg ctcaaaaaac acaagatgct agtcagataa gccaaatagc
     5101 cctgcaactc tatgaagaat taagcgagaa agaaagaggt gtccgcctat tggggattac
     5161 cctgactgga ttttaaagct caatgaaaat caaagagcaa actaggaagc tagccgcagg
     5221 ctgctcaaaa cactgttttg aggttgcaga taaagctgac gcggtttgaa gagattttct
     5281 aagagtataa aaccttgaag agttgcccct tcaaggtttt tcttatacaa ataaacggac
     5341 aaaactgtaa agtagcaaaa cactaccaag cacgatacgg tatttaccaa aaagggtgaa
     5401 gtcgtgtttt ttcacatagc tggtcaagaa gcgaatagcc accatgctga ccgcaaaagc
     5461 tactcccatc gcgaccaaga gcaaaaacaa ttgcccaaag ctcaagagtt ctcctgcttt
     5521 tacaaatttg aaaatcttta aggcactagc tccaaacata acgggaatcc caagatagaa
     5581 ggtaaattct gtcacaactg aacgactggt tctatttaac aaaccaccga caatcgttgc
     5641 acctgaacgg ctagtccctg gtaaaagagc aagaacttgg aagagtccaa tatagaaagc
     5701 ggtcgtataa ggaagcttgt ccaactctgt tacacttggc tcgatagcac gcgctttatt
     5761 gcgcttttcc aaatagatga aggcaacccc gtagataatc aacatgagag caactgaaac
     5821 catgttatgg aagtgggtat caaaccaatc atcaaattta aagacaccaa gtaaaggtaa
     5881 agtagcaatc aagaccttca accatagtct ccaagtctta cgaacttcct gtttgtcctt
     5941 agtcggttta aaaggattga gcttgttaaa ataaatcacc ataactgcta aaatagcacc
     6001 aagctgaatc acgacattaa acatggacat aaaggcttca ttttgatttt ggtattggat
     6061 aaactcctct gctaaaatca agtgacctgt actggaaatc ggcaaccatt ccgtaattcc
     6121 ttcaacaatc ccgaagaaga tagattttaa aatttcaata agatacatag atttctcctt
     6181 atattatatt taacgcagtt agctactgcc aaagcccaag tggtatactt ggaataagcc
     6241 actgtggatt agttcatttc ctccaatcgc ttgacgattt ccgaaagggt ctaaccacag
     6301 ctttttgttt caattggtaa tgagtttgat aacgcataga cgttttatct cgtctaaggt
     6361 aacaaggcaa aaagttcgtg gataaccaag tagacttgaa atactatatc tggaggtact
     6421 cccatgcttt atgtgggcat tgatgtcgct aaaaataaac acgatgttac agccttgaat
     6481 gttcgaggaa aactgttctt aaaccactca ctttttcaaa taataaagct ggttttgaac
     6541 tcttagatct gtcttttcga cagctcaacc aagactgtct catcgctctt aaacttcttt
     6601 ctgaccccaa tcgtgaacaa tttcaacacg ataatcggca agtagaacta aaaatactgg
     6661 ctagacatat tcatcgtctc aagaaaaaac agtctgattg gaaagtacaa tacactcgtt
     6721 gtcttgatat catctttcct gagttggata aaatcgttgg aaagcattca gaatatacct
     6781 accaactctt gacacgctac cctaatcctc agaaaaggct tgaggcagga tttgataagc
     6841 tgatagaaat taagcgattg accgcttcta aaattcagga tatcctctca gtcgcacctc
     6901 gttctatcgg aacaacatct cctgctcgtg aattcgaaat catcgaaatc atcaaacatt
     6961 acaagaggct cattgacaag gcggaaacat gtgtcaatga cttgatggct gagttcaact
     7021 cggtcatcac gacggttact gggattgggg gtcgtttagg ggcggtcatt ttagccgaga
     7081 ttcgaaatat tcatgccttt gataatcctg ctcaattaca agctttcgct ggactggatt
     7141 cttctattta tcagtcaggt cagattgatt tagctggaag aatggtcaaa cggggttccc
     7201 ctcatctgcg gtgggcactc atacaagctg ccaaagcatg cgctcgcttt tcacctgctt
     7261 ttaaggccta tcttaagact aagttagaat aaggaaaaca ttacaatgta gccatcatcc
     7321 accttgcaaa aaaacttatc cgaaccctgt tttatatcct aaaaaagagc tgccatttga
     7381 cgaacaaaaa gtgatgtaat ttctgaaatt aacacaggat tacctttgaa aaaatggact
     7441 ttttcaaggg ctttttgccg tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga
     7501 aatagtttag ataaaactat tgacttttct tatagtttgt ctttcttcta tcttccatta
     7561 tatcatactt tttcagtcta tggtagctct ctttaaaagg ctccgatact gccgccacct
     7621 ccgcctccag agaagccacc gccagaactt ccacttccag aagatacgga gtaggtactt
     7681 gctgtatttg cgacactagc ataatggctc atttgcgcgc ttgaatgata aaacatactg
     7741 tgccagccat aagctacata tagattgata tctggatttt caacttgaat ctgatgaacc
     7801 ttcatcaaat gactaacctt gtccgcatag ccaaataagg ttgcatagac caagagacga
     7861 ttccaaacaa caatactttc caattcagcc ttatccagtc gtgcaatctc acgcaacata
     7921 ttttcaaaac tggtccagag atagtagacc tcagctcccg cttcatttag aacaccatca
     7981 cgattatcta gtcgaagctt ccaataatag aaaacagaca aaactaaccc tagaaaacca
     8041 agtattggca aagggaggta aagatagcca tgaacgtcta aactgtacaa gaacaaacca
     8101 aatccgataa ataggggcaa gatagtcaag acacccatac ccacttgcaa agccttttcc
     8161 aaaccagtta aaggacgata gtaatctggg agcccccaga aggaaactcg ttttctcact
     8221 ccttcttgca tctggttcaa tacctcttca aaagaagatt tgagttgaag ccctcttgct
     8281 tgaatccgtt tttcatcaga aactttggct ctacgataaa gactatcaga taccttgtaa
     8341 tccgcaaaca aattggaaag agtttcttct tttttacctg aaaaagctag atttaggcag
     8401 tctttctcaa agcttgacaa accatcttct tttactagcc tcaaaccaac tgcatctcct
     8461 tctgaaatga tagagacatt cccacggtct atcacatcta gcaaggtagc ttgaataagt
     8521 tgatcaaagg tgaattttcc agctcccttg accaagggac tcacttcctc caaggaggtc
     8581 gagtagactg cttctgataa aaccataggc tctaattcca ttgggggttc atagagacga
     8641 tgatttttag catatttgat tgaaggagcg gtctttcttc tatagataaa atagaaacag
     8701 atgctcaata acaaggagat ggaaaggatc gaagggaaga tccaagtaag tagttgttta
     8761 ctttgctctt tttctttaac gatcgaatcc tctatcttat taaactcttc taaacgattc
     8821 cctttcaagc cctgatccct agcgctagca aaatcagttc gcggccagta ggcatgcaat
     8881 tcaactccac gcttagccgg aagattgtct aaacgaatag tataatcaag gttactcttt
     8941 tcaaccgttc tctctctaaa aagtttccct gtatggaaaa agagtttctc agcccccttg
     9001 tctcccctta catgaaattc aaacttttca atagactctg aactatctgt cagaggttgc
     9061 caatttaatt cagcgatatc atcataaagg aaaagtaaat tttttaagtt ccagacgagg
     9121 tcaacttcaa ctatgtcgtc ctcctgacct ggattataga ctctcacagt ataaccatcc
     9181 gcttcttctg ttacttcgct agtcacatct gctagttctg caccgttttt cgcggcctga
     9241 acctttggat gagggtcaat gtcaaacccg ctaggcatct taccagcacg tccaagtccc
     9301 acgatttggc ccttaaagtc ctcctcaaac tggtaaacta tcttctgtct aaactctgcc
     9361 gtattatctg catgaatata caaatcccct tgataagagt ttatcttgaa atcaatggca
     9421 aaaacagaga gtggaagaag gcaaaacaag cctaacacca gtaagaaaaa agtttttttc
     9481 atcaactaag cccccttttt atctttctta tcattatagc attttttcgt aagtaaaggc
     9541 ttacttatgt tgaaaaatta cgcatttttc gataaaatag gagacagtta ttttttaata
     9601 gatcagaata ggagaaatca tgagaaaaat atacttatct attttcacaa gtctcttgct
     9661 gatgctagga cttgtcaatg ttgctcaagc cgatgaatat ttacgcatcg ggatggaagc
     9721 agcatatgct ccctttaact ggacccagga tgatgatagc aacggagctg tcaaaatcga
     9781 tgggaccaat cagtatgcca acggatacga tgttcaaatc gccaagaaaa tcgctaagga
     9841 cttaggtaaa gaacctttgg ttgttaaaac caagtgggaa ggtctagtcc ctgcccttac
     9901 ttctggtaag attgacatga ttatcgcagg tatgagtcca actgcagaac gcaaacaaga
     9961 aattgccttt tcgagcagtt actacactag cgaaccagtt ctactggtca aaaaagattc
    10021 tgcctatgca agtgctaaat ctttggatga ctttaatggt gcgaaaatca cttctcaaca
    10081 aggtgtctac ctttatgact tgattgcaca aatcacaggt gctaaaaaag aaacagccat
    10141 gggagacttc gctcaaatgc gccaagctct tgaggctggt gtcatcgacg cctatgtttc
    10201 tgaacgccca gaagctctga ctgccgaagc cgctaactct aagttcaaga tggtccaagt
    10261 agaaccaggt ttcaaaactg gggaagaaga tacagctatc gctatcgggc ttcgtaaaaa
    10321 tgacaatcgt attagccaaa tcaatgccag cattgaaacc atttcaaaag atgaccaagt
    10381 tgccttgatg gatcgtatga tcaaggaaca acctgccgaa gctacaacaa ctgaagagac
    10441 tagcagtagt ttctttagcc aagtcgctaa aattctttct gaaaactggc aacaactctt
    10501 gcgtggtgct ggtatcactc ttttaatctc tatcgtcgga accatcatag gtctcattat
    10561 tggacttgcc attggtgtct tccgtactgc tcctctctct gaaaacaaag ccatttatgg
    10621 ccttcaaaaa ctagtcggct gggttctcaa tgtctacatt gaaattttcc gtggtacgcc
    10681 aatgattgtt caatcgatgg ttatctacta tggaactgcc caagctttcg ggatcaacct
    10741 tgaccgtaca ctggctgcta tcttcatcgt ttcaatcaat accggtgcct acatgactga
    10801 aatcgtccgt ggtggtatcc tagcagttga caagggacaa tttgaagctg cgactgctct
    10861 tggtatgacc cataaccaga ccatgcgtaa gattgtccta cctcaggtag tccgtaacat
    10921 cctacctgca actggtaatg aatttgtcat caatatcaaa gatacatctg tattgaacgt
    10981 tatctctgtt gtcgaacttt atttctcagg aaataccgtg gcaacacaaa cctatcaata
    11041 cttccagaca tttacaatca tcgccgtgat ttactttgtc ctcaccttca ccgtaacacg
    11101 tatcctacgc tttatcgagc gcagaatgga catggatacc tacactacag gtgctaacca
    11161 aatgcaaacg gaggatttga aataatgaca caagcaatcc ttgaaattaa acacctcaaa
    11221 aaatcctatg gacaaaacga agtgctaaaa gacatttctc tcactgtcca caagggagaa
    11281 gttatttcta tcatcggaag ctctggaagt gggaaatcaa ccttcctacg ctccattaac
    11341 ctacttgaaa cgccaactga tggacaaatc ctttatcatg gacaaaacgt cctcgaaaaa
    11401 ggctatgacc tcacgcaata ccgtgaaaag ttagggatgg ttttccaatc ctttaacctc
    11461 tttgaaaatc tcaacgttct tgaaaacaca atcgtcgctc agacaactgt cctaaaacgc
    11521 gaacgcacag aagctgaaaa gattgccaaa gaaaacctgg aaaaggtcgg catgggagaa
    11581 cgctactggc aagccaaacc aaaacaactc tcaggtggtc aaaaacaacg tgtggccatc
    11641 gctcgtgccc tctccatgaa tccggacgct attctctttg atgaaccaac atcagctctc
    11701 gatccagaaa tggttggaga agtcctcaaa atcatgcagg acctggctca ggaaggcttg
    11761 accatgattg tcgtaaccca tgaaatggaa tttgcccgtg atgtctctca ccgtgttatc
    11821 tttatggata agggcgtgat cgctgaagaa ggtaaaccag aagacctctt caccaatcct
    11881 aaagaagacc gaacaaaaga gttccttcaa cgctatctca aataaaaaga aaaggctgca
    11941 tcaaccgtgc agtctttttg ctgtcctcaa aatgaaaagg cagattctct atctctacta
    12001 cttgaaggtc aagaatccgc cgttatccaa agattaatct tcaaattttt cataattttt
    12061 ttcatagaaa tcaattaggc ctagggctgt ttcaaatgaa atatttttta cttttgcacg
    12121 accctgcgcc agagcaatga tagacatttc acgcgcattc gtttctttag agatacggta
    12181 gcctgtgatt ttcttatcac gaacccagcc aacaactgat tctacttttt caaagtttga
    12241 cttagccatg tttttctcct attttcttct ttataatatt taattgtata cgtttttact
    12301 acttttgtca ataaaaaaaa acatatattc aacgagaata attagttcag aattttctta
    12361 cttccttttt aaatccgata atatataggt tttgctagcc tctacaccat aaatatttgc
    12421 taataaaaat actgtattat taccctctta aggtgcgaaa ttattcaagt tcttaaaaat
    12481 gcttctctat ttccgtaaga tagcttattt cttcgattta agaactgaag atgatagttc
    12541 taacctttag aaatccaagc cttcactagc tcaaaaactc ctatctttct tcctcaataa
    12601 atcatctgag agataggtat tccttatatc cttcaaattc atcactcctt tggatattga
    12661 ggtgctagcc tagaagcaga cacccgatta tctaaaccat ccttaataaa gatgacaaga
    12721 cagataagct cagttaatta cttatatatc cttttaatat ggtatatttg tcaacaaaaa
    12781 gaaatcaaat cataccttat actcaatgaa aatcaaagag caaactagga agctagtcgc
    12841 aagttgctca aaacactgtt ttgaggttgc agatagagct aacgtggttt gaagagattt
    12901 tcgaagagta ttaaagacag tgtgactatg cttgtcaata gataggaaat caaaatgaag
    12961 gatggaaatc tgagccaaac atcataagtg ctataatgaa cagaagtaag aattgcacga
    13021 taagttttct aaaaccatag gaatcgtccc ctttcttcat cttcattata gcacatatac
    13081 atcagttgta caaataatat gatatttttt tattagtcct cagacaagca tattataaag
    13141 cgtttcatta ccatttaagt taatataagc tggatcaaaa ccttccattc tacggatcaa
    13201 acctgcataa tcatgcttat ctgccaaagc gatcccaatc aatactgggc ctgttccctt
    13261 gctagctcgt ttgatatact caaaacgtgt gatatcatca tttggcccca ggatatcatt
    13321 tacaaactca cgcaaagctc ctggacgctg tgggaaattg accacaaagt aatgtttgat
    13381 accatcataa atcaaggcac gctcttccat ttctggcata cggttgatat cattatttcc
    13441 tccagaaatg atacaacaaa tggttttccc cttaatatat tcagctaaaa cctctaaaga
    13501 ggcgatacta gccgctccag caggctctgc gactatccct tgcttagagt aaaggtcaat
    13561 caaggtttca gaaatcaatc cctcatcgac acctaccaaa gtttgaatat gttgacgagt
    13621 tgcttcatag gtcaactgac ctaccttttg cacagcaatc ccatccgcaa atttatcaat
    13681 ttccttgagt ttgactggac ctccagcctc aaaggcagct ttcatggaac gcgctccatt
    13741 cgcctctact ccgataacct caatctctgg acttgtttcc ttgatatagg tagaaacccc
    13801 ggcaatgaga ccgccaccac caacaggaac caagacagca tcaaaatcaa tcgattcttt
    13861 tcgagcttct tctaaaatct cataagcaac tgttccttga cctgcttgaa catgagcatc
    13921 atcaaaagga tcaataaagg tacgattttc agagactgta aattcttgag ctgctttggc
    13981 tgaggcatca aaggtatctc caactagttt aatagttaca aaatccccac caaaaaagcg
    14041 aacctgacca atcttttgtt gtggcgtagt aataggcata aagatagtag caggaatttt
    14101 catttcatta caagtatagg ctactccctg cgcatgattt cccgcagaag cgcagactac
    14161 cccacgttca cgttcttcct tgctgagctg ggaaatggca taataggcac cacgaatttt
    14221 aaaggagcga acacgctggg cattttcttt tttcaaataa atcttagcac catacttctc
    14281 cgataaataa tgatcgtaat ccagtggagt attcacaacc acaccgttca agaccttgtg
    14341 agccttgatt atatcttttg aacttaacat ataaaacctc tttttctata aaaaacagtc
    14401 actaatgact gttttttagt tattcatctc cgaaaacttc agtaacactt tcatggtatt
    14461 tatgagccat acgaatcgaa aactctttag gaagttcata acgatttgtg gaaatccaat
    14521 catataacca ttctaccaaa ctttcttcac tatcattacg atggaagata aaatagttta
    14581 aaatttcttt atattctaca tcattcaaat ccaacgtgtc tacaaattga ctacgaggaa
    14641 caaaattaga atctaatttt cttagttgat ctgtcaattc tcccaattgt aaatccaact
    14701 gaaaaaatag tttttgcagt tgcctatcag tttcatcaca tcctgtcttg atagaaaaca
    14761 aattggtaat attcatatga tttcaacccc taaataagta catctaatat cccacgaata
    14821 gctgaagcta aagttttcgc agtccagtca tttaaacccg attctttcaa tccagatgca
    14881 ataatttgct ctatttgata taaaccgcca tctatcgtct catttattct gcgaagagga
    14941 ccttcaatat aggataaagc ttctccgaat ctaacagctg atttaggtcc taatgattta
    15001 ccaactatat ttgttaatgt tttttatttc tcaaaatcca tttcgctata taacgagcag
    15061 atttagtcgc accagctctc tcaaacggag aatgaatttc aagaccttct tctctagcta
    15121 tttgtgccaa tttgaagaat tgttcaaagg tcatatgcaa cctaccatct tcaaaattag
    15181 catcatcata aatgttaatt acagcatttt catcatacga ccaatctgct ttattttggt
    15241 ctgctagcac tattaccgac ggtgtaatta cattatacaa ctagaaccaa taataacgat
    15301 gcaatttttc tcataatctt tttcataaaa tcatctccag cgctatatat ttctaattag
    15361 ttatagattt tgaatgcatc atcgtcgttt ttaccaacga atggcattgc tttacgcaat
    15421 tctgcaccaa ctttttcaat ttcaaggtta gctgcttgtt cacggtaagc agtcaatttt
    15481 ggacgtccag ctttatagtc atttacaaag tcatttgcaa atttaccatt ttggatgtct
    15541 gccaagacag ccttcatatt ttctttaact tgttcagtga ttacacgtgg acctgataca
    15601 tagtcaccgt attcagcagt gtttgaaata gattgacgca ttttcttgaa tccaccttca
    15661 tagatcaagt caacgatcaa tttcatttcg tgaagaactt caaagtaagc caattctgga
    15721 gcgtaacctg cttctgtcaa gacttcgaaa cctgcttcga taagggcagt caaaccacca
    15781 caaagtacag cttgttcacc aaacaaatct tcttcagttt cttctttgta agttgtttca
    15841 agaagaccta cacgagccgc tccaacacct ttacaccagt ccatagcaat gtttttagca
    15901 tttcctgttg catcttggta tactgcataa agagctggaa caccaaatcc ttcttcgtaa
    15961 gtacgacgta ccaagtgtcc tggtccttta ggagcacaca tgaagacatc tacatccgca
    16021 ggaactttga taaattcaaa gtggatgttg aaaccatggg caaatccaac tgcgtttcca
    16081 gcttccaagt ttggagcgat ttctgcttcg tacaattctt gttgaatttc gtctggcgcc
    16141 aagatcatga taacatcagt caacttagta gcttctgcta ctgtgtaagt atcaaatcca
    16201 tcttcttttg ctttatcaaa agatttacct ggacgtacac ctataataac gtcacgacct
    16261 gaatcacgca agttttgagc atgcgcatgc ccttgtgaac cataaccgat aacggcgatt
    16321 tttttaccgt caagtgctgc tactttaaca tctttttcat attccatttg aactgtcata
    16381 gcttttctct cttttctatt atttattgcc ttttaggctg gtttaataaa tttaagttgg
    16441 atttttaatc gcgggtaaat ccagttgcac ccgttcgagc aatattgcga ataccgtatg
    16501 ggcgaatgac tctcaatagg gcttcgctct tttctgcatt tcccgtcatc tgaatggtaa
    16561 tcgagcttgg cgctacgtct accactgttg cacggaaagg ttgaataatc gctaaaatct
    16621 cagctctctt ctcagctggc gctgacatct taaccaaaat cacctcgcgc tccaaatgag
    16681 gcttgtctgt aatatctcga atgcgaatca catcaatctg acgattgagt tgtttgatga
    16741 tttgctccac ttcatcatga gaagcaacat caataataat agtgatacgc gatacattcg
    16801 gatcttctgt tgctccaaca gagatgcttt caatattaac ctgacgacga gataggacac
    16861 ctgtaaagcg attgaggact cctgaacgat tttgtagttt tgctgttaac attctacgca
    16921 tggaactgca cccccaacat ctcatgatta ctcttaccag ccggtaccat tggtaacacc
    16981 tgttccttac gagaaatatc tacctcaatt agcataggaa catcctcagt gatgacttca
    17041 aggtcttgag ccaaggtctc aggattgtca aacttatagt ttttaatacc ataagcctgc
    17101 gccatcaatt ggaaatcagg aagggtatca aagaccgact ctgatgttct gccttcatag
    17161 aaggattcct gccactggcg aaccattccg agtgaatgat tgttcagcat aaccaccttg
    17221 attggcacct tgtaaatatt caaaatagcc aactcctggt tagtcatttg gaaaccacca
    17281 tccccaacaa acaagactac ttccttatct gggttagcaa ttttagcacc gattgctgct
    17341 ggaattccaa agcccattgt tcccaaacca cctgaagtca ctaactgacg ttcattttgg
    17401 tagggataat actgagctgt ccacatttgg tgttgaccaa cgtctgttac cacaatggca
    17461 tctccattcg tcaattcacc aattcgttca ataactgctt gcggttgaac cacacgctct
    17521 ttcttgtcat aagaacgaac acgattcttg tctttagtga ctttctcaat ccacttttca
    17581 gtattgttgt gaactgttgg ttctgctagc aacatttgca aggccttctt agcatctcca
    17641 actacaggaa tgtctgcact gataatcttg ccaatctcag ctgggtcaat atcaatgtgg
    17701 gcaaccttag cattcttagc gaaagtctta ggattccccg tcaaacggtc atcgaaacga
    17761 gaaccaatac taatcataaa gtccgcttcc gtcatggcaa tatttgctgc gaatgacccg
    17821 tgcatgcctc ccattccaag aaagagtggg tgactcgttg caattgttcc ttgtcccaaa
    17881 agactggtta ccactggaat ttgatagcgt tctgcaaatt catttagttc cgtagcagcc
    17941 tcagcataac taattccacc accagctaac aagactggct ttttagcctt ggacaattgc
    18001 ttcaagattt tcttgatttg catatcattc ggctcaagag tcggctgata acttggtaaa
    18061 ttcacttctg gtgaataaat gaaatctgtt tctaaagcag atatgtcttt tggtaggtca
    18121 attacaactg gccctggacg gcctgtagtt gcgatatgga cagcttccgt aatgatacgc
    18181 ggaatatcag ctgtctcacg aacttgataa ttgtacttag tgattggcat ggtaattcct
    18241 acgatgtctg cctcctgaaa ggcatccttc ccaatccctg ctcgcgccac ctgacctgta
    18301 aagaccaaaa ggggaacgct atcgctcata gcatccgcaa tccctgtaat ggcatttgtt
    18361 gctcctggtc cactagtgac gacggcaaca cccaactttc cagttgattt ggcataacct
    18421 tcagcttcat gcaaacaacc ttgctcatgg cgccctagaa tgtggcgaat gcctttaaaa
    18481 ttatatatcg catcataaaa aggcaaaacc gcaccaccag gataaccaaa gatggtatca
    18541 actcctaaat cacgaagtgt ttccaaaact aggtccgacc ccgtcttagg agattctaaa
    18601 ctgattttct ccattgttcc cctttctttc ctcttaaaaa taacttgtta ctatcatacc
    18661 attttttcaa aatttttcaa gataaaagaa gaaattttct gaattttcta ttttaacgtt
    18721 tatttatgaa tattattttt atttttattt aaaagatacc gatttcattt actaaaaaag
    18781 aaaaaagaac tgatttctca gtccttcatt aatcttattc cacactaaat aggtatgggt
    18841 aaacaggttg ttgaccttgg tgaatctcga cttcaacgtc ttcgaattct tctacgattt
    18901 cttgagcgat ttcattggca agttcttcgc ttccgtcttc accgacatag aaggttacga
    18961 tttcactgtc ttcatccaac atatgtttca aggtttcagt caatgtttgg tgcatatcag
    19021 ggtttgacac aagaattttt ccatccacca tacctagatt atcgttttca tggatttcta
    19081 agccatcgat cgttgtatca cgcacggctg ttgtgacgct tccgctaacg acatcgctaa
    19141 gagcagctgt catacgctct tggttttctt caatggactt gcttggatca aaggcaagaa
    19201 gacttgtcat accttgagga agagtgcgag cctctaccac tactgctggt tgctccaaaa
    19261 cttctgccgc agattgagct gccatgaaga tgttcttgtt gtttggcaag aagatgatgt
    19321 tacgggcatt gacctgttca acagccttga taaagtcttc tgttgaaggg ttcatggttt
    19381 gaccgccttc gataacatag tccacgcctt gagaacagaa gatatctgct agacctttac
    19441 cagccaccac agcaattaaa gcatactctt tttcttcagc cgacttgata acttgagtag
    19501 cttctttctc aacctgtgct tcgtgttggt tacgcatatt gtcaactttt accttgacca
    19561 agctaccata tttgagacct tcttgcataa caagtcctgg atcttctgta tgaacatgga
    19621 ctttgacaat ttcatcatcg ttaacaacga ggagagaatc cccaagctca tccaagtagt
    19681 tacggaattc atcgtaatca aaatctttag cataggttgg accttgctta agagctacca
    19741 tgatttcagt acagtaacca aacgtgatgt cctcagtcgc tacgtgacca gctacagact
    19801 tatgatgctc tacattgatc atctcactca tgttggcagg agtcgctaca aagtcctcag
    19861 atgcaatata ttcgccagta agggctgaaa ggaaaccttc gtagatgaag accaatcctt
    19921 gaccacctga gtccacaacg ccaacttctt tcaatactgg aagcatgtct ggtgttttag
    19981 ctagagctgt tttagcacct tccaaggctg cgcgcatgac ttcaacagtg tcatctgttt
    20041 gctcagcttt tttcttagca ccgatagcag ctccacgaga aactgtcaaa atcgttcctt
    20101 caacaggttt catcactgcc ttataggcaa cttccacacc tgattggaag gccagagcca
    20161 agtcttgacc tgttaactcg tctttatcct tgatagcttg ggaaaatcca cggaaaagct
    20221 gagacgtaat cactcctgag ttcccacgcg cacccatcaa aagcccttta gcaagaatgc
    20281 tcgctacttc tccaactgta gaagctggct tgtctgcaac ttctttagca ccattttcaa
    20341 tggtcattcc catatttgtc ccagtatctc catctggaac tggaaagacg tttaatgaat
    20401 tgacatattc agcttgctta ttcaagcgag ttgatgcagc ctgcaccatt tcttgaaata
    20461 agctagtagt aatttttgac acggttattc tcctacaact ttgatatttt gaatgtagac
    20521 atttacagtc tgagcagtaa ttccaagctg gttttccaag ctaaaggcaa cacgctcttg
    20581 aatgtttttt gacacttcac taatctttgt tccgtagctt aacacggtat atacatcaac
    20641 tgcaatactg ccatcttcgg ctgcctttac gacgacacct ttagaataat tttccttacc
    20701 tagcagggct tggaaattat ctttgagggc atttttacta gccataccga ccacaccaaa
    20761 aatctcagtt gctgctccac ctacgacggt tgcaatcact tcatctgtta gttcgatttg
    20821 accatctttt gtattaattt ttacagtcat cctttttacc tcaactagtt gatactctat
    20881 tttatcatat ttcagcccaa gtgtaaaagc agaatgatgt atcagcggat atttactcta
    20941 tttttcaaac gatgttatac ccacaataaa agaaaaaaga ccctaaggtc tcctttgctt
    21001 ttattattaa acgcgttcaa ctttacctga tttcaaagca cgagctgaag cccaaacttt
    21061 tttaggttta ccatcgataa gaacagtaac tttttgaagg tttggtttta cggcacgttt
    21121 tgtttggttc atcgcgtgtg aacggttgtt tcctgataca gtcttacgac ctgtaaagta
    21181 acatacttta gccattgtgt tttcctccta ttagatctaa tatagcggat gtgctagcac
    21241 cacataccgt actatgttat cacactttct tgttttttgc aagggaattg gaagattttt
    21301 tatttgtgtc ttaaatcagg tcttgcgtga cattttctgc tctccacatg ccattgttga
    21361 ttaacagaac accagaatta aaattatgtg tataaaaatc atctctaact gcagctaagg
    21421 gtatagccgt caagtccaaa tcccacagct catctatcga ttttcttaca acaatatcta
    21481 aatccaaata cagtacacga gactcgctta catactttgg aataaaatac ctaaaaaagc
    21541 cgcatatgaa agtccctcaa aggggagacg ataacctttc agaatactac tgtcaatcta
    21601 aacattcaca atctcactat tcaaagtctc tagtcttttt tccatcaatt ggaaccattc
    21661 tcgcggaagg tcatcattaa aaacataaaa cttaagatta taatagatga acacaaagag
    21721 attttattgt tgtttcaact ttatccatat aagcattatc tgcacctaag acaatcgctt
    21781 ttttctcttc tttcactctt tatctcattt ctttttattc ccatcatatg tttctacgta
    21841 accattattt tcgcccattc gttcgtaaaa ccataccagt ggagatttta gatgaagtcc
    21901 cattacggtt tacaattttt acattacgac acggagtttt acaaatcgat ttcatttgcc
    21961 aaacgtagtt agtaaggcag ttagctagtt cgccaaatag cgactagcgt ccaacaattt
    22021 ggaactttag ttccaattgt tggtactgag tcacatcttc tcctctaact ctacgtctgg
    22081 atacttgtcc gcaaaccagc ggagggcaaa gtcattttca aagagaaaga ctggttggtc
    22141 aaaacggtct ttggctaaga tattgcgact tgacgacatc cgttcatcca agtcctcagg
    22201 cttgatccaa cgaacggtct ttttacccat tgggctcatg accacttccg cattgtattc
    22261 gccttccata cggtgtttaa agacttcaaa ctggagttga ccaacagctc ccagcatgta
    22321 ctcacctgtt tggtaattct tataaagctg aacggctcct tcttgcacca attgctcaat
    22381 ccccttgtgg aaggattttt gcttcataac attcttagca gaaactttca tgaaaatttc
    22441 aggagtaaag gttggcagtg gttcaaattc aaacttgttt tttccaaccg tcaaggtatc
    22501 cccaacctga taagtaccgg tatcgtaaac cccgataata tcacctgata cggcattggt
    22561 cacattctca cgactctccg ccataaactg ggtaacatta gatagtttgg cacccttacc
    22621 agtacgaggg agattgacac tcatgccacg ctcaaattcg cctgatacga tacggacaaa
    22681 ggcaatacgg tcacggtgac gaggatccat gttggcttgg attttaaaga caaagcctga
    22741 gaaatccttg tcataaggat ccacaatttc accgtctgtt ttcttgtgac catgtggttc
    22801 tggagcaaac ttgaggaaga tttcaaggaa ggtctgcaca ccaaagtttg tcagggctga
    22861 accgaaaaag acaggcgtca attctccagc cagaatagct tcctctgaaa actcattccc
    22921 agcttcattt aaaagctcaa tgtcatcctt gacttgctcg tagaaaggat tgctaccaaa
    22981 gagtttgtcc ccgtcttcta gactggcaaa acgctcatcc cctttgtaaa gctctaaacg
    23041 ttggttatag aggtcataca agccctcaaa ggctttcccc atcccgatag gccagttcat
    23101 agggtagcta gcaatgccca agatttcttc caattcttgc aagagatcca aaggctcacg
    23161 accgtcacgg tccagcttgt tcataaaggt aaaaactgga atgccacgat gtttcacaac
    23221 ctcaaacaat ttcttggttt gagcctcgat ccccttggca gagtccacga ccatgaccgc
    23281 agcatccacc gccatcaagg tacgataggt atcttctgag aagtcctcgt gccctggcgt
    23341 gtctaagata ttcacgcgct tgccgtcgta gtcaaattgc ataacagatg aagtaacaga
    23401 aatcccacgt tgcttctcga tatccatcca gtcagattta gcaaaagtcc ctgttttctt
    23461 cccttttacc gtaccagcct cacgaatctc acccccaaag tagagtaact gctcagtgat
    23521 ggttgttttc cccgcgtccg ggtgggagat aatggcaaag gtacgacgtt tcttaatttc
    23581 ttcttgaata ttcataagtt ctctttcttt gattctctat ttttcttgtt tcaatagctg
    23641 agaatgattt ttacattgga ttttaccatt cctttcaaca ttccattata tcggatttta
    23701 gcattttttt caatttctat ttcttttcac ttccccctcc cttatttata ggaaaatatg
    23761 gtaaaataga acagactaaa aatcatcatt tcacgaaagg atgcaagatg aaaattacgc
    23821 aagaagaggt aacacacgtt gccaatcttt caaaattaag attctctgaa gaagaaactg
    23881 ctgcctttgc gaccaccttg tctaagattg ttgacatggt tgaattgctg ggcgaagttg
    23941 acacaactgg tgtcgcacct actacgacta tggctgaccg caagactgta ctccgccctg
    24001 atgtggccga agaaggaaca gaccgtgatc gcttgtttaa aaacgtacct gaacaagaca
    24061 actactatat caaggtgcca gctatcctag acgatggagg agatgcctaa tgacttttaa
    24121 caataaaact attgaagagt tgcacaatct ccttgtctct aaggaaattt ctgcaacaga
    24181 attgacccaa gcaacacttg aaaatatcaa gtctcgtgag gaagccctca attcatttgt
    24241 caccatcgct gaggagcaag ctcttgttca agctaaagcc attgatgaag ctggaattga
    24301 tgctaacaat gtcctttcag gaattccact tgctgttaag gataacatct ctacagacgg
    24361 tattctcaca actgctgcct caaaaatgct ctacaactat gagccaatct ttgatgcgac
    24421 agctgttgcc aatgcaaaaa ccaaaggcat gattgtcgtt ggaaagacca acatggacga
    24481 atttgctatg ggtggttccg gtgaaacttc acactacgga gcaactaaaa acgcttggga
    24541 ccacagcaag gttcctggtg ggtcatcaag tggttctgcc gcagctgtag cctcaggaca
    24601 agttcgcttg tcacttggtt ctgatactgg tggttccatc cgccaacctg ctgccttcaa
    24661 cggaatcgtt ggtctcaaac caacctacgg aacagtttca cgtttcggtc tcattgcctt
    24721 tggtagctca ttagaccaga ttggaccttt tgctcctact gttaaggaaa atgccctctt
    24781 gctcaacgct attgccagcg aagatactaa agactctact tctgctcctg tccgcatcgc
    24841 cgactttact tcaaaaatcg gccaagacat taagggcatg aaaattgctt tgcctaagga
    24901 atacctaggc gaaggaattg atccagaggt taaggaaaca atcttaaacg cggccaaaca
    24961 ctttgaaaaa ttgggtgcta tcgtcgaaga agtcagcctt cctcactcta aatacggtgt
    25021 tgccgtttat tacatcatcg cttcatcaga agcttcatca aacttgcaac gttttgacgg
    25081 tatccgttac ggctaccgcg cagaagatgc gactaatctt gatgaaatct atgtaaacag
    25141 ccgtagccaa ggttttggtg aagaagtgaa gcgccgtatc atgctgggta ctttcagtct
    25201 ttcatcaggt tactacgatg cctactacaa gaaggctgga caggtccgta cacttatcat
    25261 tcaagatttc gaaaaagtct tcgcggatta cgatttgatt ttgggtccaa ctgctccaag
    25321 tgttgcctat gacttggatt ctctcaacca tgacccagtt gccatgtact tagccgacct
    25381 cttgaccata cctgtaaact tggcaggact gcctggaatt tcgattcctg ctggattctc
    25441 tcaaggtcta cctgtcggac tccaattgat tggtcccaag tactctgagg aaaccattta
    25501 ccaagctgct gctgcttttg aagcaacaac agactaccac aaacaacaac ccgtgatttt
    25561 tggaggtgac aactaatgaa ctttgaaaca gtcatcggac ttgaagtcca cgtagagctc
    25621 aacaccaatt caaaaatctt ctcacctact tctgcccact ttggaaatga ccaaaatgcc
    25681 aacactaacg tgattgactg gtctttccca ggagttctac cagttctcaa taaaggggtt
    25741 gttgatgccg gtatcaaggc tgctcttgcc ctcaacatgg acctccacaa aaaaatgcac
    25801 tttgaccgca agaactactt ctaccctgat aatcccaaag cctaccaaat ttctcagttt
    25861 gatgagccaa tcggttataa cggctggatt gaaatcgagc tagaagacgg tacgaccaag
    25921 aaaattggta tcgaacgcgc ccacttagag gaagacgctg gtaaaaacac ccacggtaca
    25981 gacggctact cttacgttga ccttaaccgc caaggggtac ctttgattga gattgtatct
    26041 gaagccgata tgcgttcgcc agaggaggcc tatgcttatc tgacagccct caaggaagtt
    26101 atccagtacg ctggcatttc tgacgttaag atggaagaag gttctatgcg tgtggatgcc
    26161 aacatctccc ttcgccctta tggtcaagaa aaattcggta ccaagactga attgaagaac
    26221 ctcaactcct tctcaaacgt tcgtaaaggt cttgaatacg aagtccaacg ccaggctgaa
    26281 attcttcgct caggtggtca aatccgccaa gaaacacgcc gttacgatga agctaacaaa
    26341 acaaccatcc tcatgcgtgt caaggaaggg gctgctgact accgctactt cccagaacca
    26401 gacctacccc tctttgaaat ttctgacgag tggattgagg aaatgcggac tgagttgcca
    26461 gagtttccaa aagaacgtcg tgcgcgttat gtatctgacc ttggtttatc agactacgat
    26521 gctagtcagt tgactgctaa taaagtcact tctgacttct ttgaaaaagc tgttgcccta
    26581 ggtggtgatg ccaaacaagt ctctaactgg ctccaagggg aagtcgctca gttcttgaat
    26641 gctgaaggta aaacactgga acaaatcgaa ttgacaccag aaaacttggt tgaaatgatt
    26701 accatcatcg aagacggtac tatttcatct aagattgcca agaaagtctt tgtccatcta
    26761 gctaaaaatg gcggtggcgc gcgtgaatac gtggaaaaag caggtatggt tcaaatttca
    26821 gatccagcta tcttgatccc aatcatccac caagtctttg ccgataacga agctgctgtt
    26881 gccgacttca agtcaggcaa acgtaacgcc gacaaggcct ttacaggatt ccttatgaag
    26941 gcaaccaaag gccaagccaa cccacaagtt gcccttaaac tacttgcaca ggaattggcg
    27001 aagttgaaag aaaactagac agaacaaaac cagccctaag gttggttttt tcttctctac
    27061 caactcccaa taactatttt ggctttattt ccagagtatt ttatggtaaa atgaagagta
    27121 ataatattta ttaaagaggt aaaaacatga ttgaagcaag taaattaaaa gctggtatga
    27181 cctttgaaac agctgacggc aaattgattc gcgttttgga agctagtcac cacaagccag
    27241 gtaaaggaaa cacgatcatg cgtatgaaat tgcgtgatgt ccgtactggt tctacatttg
    27301 acacaagcta ccgtccagag gaaaaatttg aacaagctat tatcgagact gtcccagctc
    27361 aatacttgta caaaatggat gacacagcat acttcatgaa tacagaaact tacgaccagt
    27421 acgaaatccc tgtagtcaat gttgaaaacg aattgcttta catccttgaa aactctgatg
    27481 tgaaaatcca attctacgga actgaagtga tcggtgtcac cgttcctact actgttgagt
    27541 tgacagttgc tgaaactcaa ccatctatca aaggtgctac tgttacaggt tctggcaaac
    27601 cagcaacgat ggaaactgga cttgtcgtaa acgttccaga cttcatcgaa gcaggacaaa
    27661 aactcgttat caacactgca gaaggaactt acgtttctcg tgcctaatct ctagaaagag
    27721 gtcattctat gggaattgaa gaacaacttg gcgaaatcgt tatcgcccca cgtgtacttg
    27781 aaaaaatcat tgctatcgct actgcaaagg tagagggtgt tcactctttt tcaaacagat
    27841 cagtgtctga taccctttca aaactttcac tcggccgtgg cgtttatctt aaaaacgtgg
    27901 acgaagaact cacagcagat atctatctct accttgagta cggagtaaaa gttcctaagg
    27961 tagcggttgc tatccagaaa gctgtcaaag atgccgtccg taatatggct gatgtagaac
    28021 tcgctgctat caatattcac gttgcaggta tcgtcccaga taaaacacca aaaccagaat
    28081 tgaaagatct atttgacgag gacttcctca atgactagtc cactattaga atctagacgc
    28141 caactccgta aatgcgcttt tcaagctctc atgagccttg agttcggtac gaatgtcgaa
    28201 actgcttgtc gtttcgccta tactcatgat cgtgaagata cggatgtaca acttccagcc
    28261 tttttgatag acctcgtttc tggtgttcaa gctaaaaagg aagaactaga taagcaaatc
    28321 actcagcatt taaaagtagg ttggaccatt gaacgcttaa cgctcgtgga gagaaacctc
    28381 cttcgcttgg gagtttttga aatcacttca tttgacactc ctcagctggt tgctgttaat
    28441 gaagctatcg agcttgcaaa ggacttctcc gatcaaaaat ctgcccgttt tatcaatgga
    28501 ctgctcagcc agtttgtaac agaagaacaa taaaaagaaa aagtgtttga tatctatcaa
    28561 acactttttc tttgcctccc actatctaaa aaaatgataa tagatataat tgtaaacaaa
    28621 aatccagata ggttttgcat gattgagaaa gttaaaaaaa ctatggcaga gaatcgttaa
    28681 tctcagattg tcggtagaac gataaacaag ggcaaaaaag aaaccaatca gactataata
    28741 taataaacta attggatctc tgtgagatag tatcaaatgg ctaatcccaa agataaggcc
    28801 tgataagatg acatctaaat agtactttga cttaggaaag aaggtattca tcaaataccc
    28861 tctatcaaga gtctcctcaa aaacaggacc gatgattaca agcaggacaa aagataagat
    28921 agtcgataaa aaggttggtt gtccatttga aagaaccacg gtaaaatact catcatgaat
    28981 attcctatgg ttaatcaaat gagcatagcg tgcctaaaaa ttaccgagaa tctgataaac
    29041 cacatacgtt gcaaataagt agaagacaaa tgaccagttc cagctctttt tttcaaagat
    29101 aaagagcatc tttttctttt ttaacctcca aatcaataga aggaaacttc ccactaatac
    29161 cattgttaaa ataagagaat agacatcagc tcctaaccct aaaatgatcg tcacatacaa
    29221 tccaattgtt tgtggtaaat aggtagatag taaaataata agcaaaaata ttccaaattg
    29281 tcttagtttt tttgtgtttc tcatcgtact tttttgaaag attaccctgc tcggaagccg
    29341 tacttccaag catctatata agaattaagt gccccttgcc tcatataggg agcaaattct
    29401 ctataatata accatctact atatccatct tcccaaacag caagaccacc tgaagtttgc
    29461 tccaagtcct cagttgaaag aactgtaaat gtatttgtac ctgtcattgc aagtaccttc
    29521 ttaaaataga ttgttgtagg ctcacattta tagtatattt ctttttttgt ctattttata
    29581 gtctatctcc tcaactgtca atttttcaac ctgaattgca tttttccata aaaaatgaga
    29641 cctttctagt ctcatttagt cattcttagt attttctaaa tcgttgatag cgttcttcca
    29701 gcaactcttc tagcggtttt tgtgaaagtc tagccagctc cgtttggagt tcttttttga
    29761 cactcttaat cagttcttta ctagaaagtc ctacttcaga aatcacctta tccaccacgt
    29821 ccatttctaa cagttcatgc gaagtgattt tcatcagttc tgctgcttcc atggcgcgag
    29881 taccgtcctt ccataaaatg gaagcaaagc cttctggact gagaatggca tagatagaat
    29941 tttccagcat ccagacacgg tccgcgacag ctagagccag agccccgcct gaaccacctt
    30001 caccgataat aatggcgata ataggaactt tcaggtcact catttccatg agattgcgag
    30061 cgatagcttc cccttgacca cgttcttctg ctccgacacc aggataagca cctgctgtat
    30121 tgataaaggt cacaactgga cggccaaatt tctcagcctg tttcatcaac cgcagtgcct
    30181 ttcggtaacc ttctggatgt ggttggccaa aattccgttt gaggttgtct tgcaaactct
    30241 tgcctttttg gataccaacc actgttacag cttggtctcc aagccaacca ataccaccaa
    30301 caactgcacc atcatcacga aaagaacggt caccatgtaa ttggataaat tcatcaaaaa
    30361 tgcctgtcgc aaagtccaag gttgtcaagc gactctgctc acgcgcttct ctgactattt
    30421 ttgcaatatt catctaggac tccctccatg caatctgact aggctagcaa tcgtatctgg
    30481 taagtctctt cttttgacaa tagcatccac aaagccatgt tctaatagga attctgcctt
    30541 ttggaaatcc tcaggcaagc tttcacgaac cgtattttca atcacacgac gtccagcaaa
    30601 accaaccaag ctctgtggtt cagccagaat gatatcgcct tccatagcga aagaagctgt
    30661 cacaccacca gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag catttgaatg
    30721 gcgtttaacc gccgcagaga tcttagccat ctgcatgaga ctcatgattc cttcctgcat
    30781 acgggctcca ccagaggctg tgaataggac aactggcaat ttttcgacag tcgcatactc
    30841 aaacaaacga gtgatttttt cacctacaac cgtacccata gaagccatga taaagttaga
    30901 atccataatc ccaagagcca cagtctgacc tttaataaga gcagttcctg tcacaacggc
    30961 ttcatgcaga cctgtttttt cacgcataga tgccagtttc ttttggtaac cagggaaatg
    31021 caagggatcc ttgctttcaa tccctgtaaa caattctttg aaggttccca tatcaatcgt
    31081 caaagccaag cgttcttggg cagaaatacg aaaggtatag ctacagtgcg gacagatacg
    31141 ttcacttccc agatccttct gatagatggt atgcttacag cctggacact gggaaaataa
    31201 ttcatctgga acctctggct tagcttgagg tttttcccta accgaacgat tgggattgat
    31261 tcgaatatac ttatcttttt tactaaatag agccattgat tccccttttc ggtttaaact
    31321 cttaaagtca ttttattctt tttcttgata tttaggtaag aaggtttcca tcaagaagga
    31381 agtatcataa tccccagcaa tgacattgcg atctgaaatg aggtcaagct ggaaatctgc
    31441 attggtctgc actccttcaa tctctaattc atagagggca cgttgcattt tcatcaaggc
    31501 gtcaaaacga ttttcgccgt gtactatgat tttggcaatc atactatcat aataaggcgg
    31561 aatggtataa cctggataaa ctgctgaatc cacgcgcaag ccaactccac cacttggcag
    31621 atagagatta gtaatcttac ctggacttgg agcaaagtta aaggctgggt tttctgcatt
    31681 gatacgacac tcgatggcat gaccgcgtag gacaatatct tcttgcttaa cagacaaagg
    31741 ctgacctgcc gcaatgcaaa tctgttcctt aacgatatca acacctgaaa caaactctgt
    31801 tactggatgt tctacctgaa cacgagtatt catctccatg aaatagaaat tgctacttgc
    31861 ttcatcaaga agaaattcaa tggttcctgc attctcatag ccaacaaact ctgccgctcg
    31921 aacagcagca gcacctattt catgacgcag cgtttttccg attgcaatcg agggactttc
    31981 ttccaaaacc ttttggttat tcctttgaag agaacaatcc cgttcaccca agtgaatcac
    32041 atgtccatgc tcatcaccta ggatttgaac ctcaatgtgc cgagctggat agataacccg
    32101 ttctatgtac atggcaccat tgccataatt ggccttggcc tcactagagg cagtttcaaa
    32161 ggcagaaacg aggtcatctg gtttttcaac cttacgaatc cctttaccac ctccacctgc
    32221 tgaagccttg agcataacag gatagccaat tttttcagca acaatcaaag cttcttcaga
    32281 gttatgcact tctccatctg aacctggtat aacaggcaca cctgctttaa tcatctgagc
    32341 acgcgcattg atcttatccc ccatcatatc cataacatga ccagatggac cgataaactt
    32401 gatacctact tcttcacaca tggtcgcaaa tttggaattt tcactgagaa atccaaaacc
    32461 agggtgaata gcttctgcct cagtcaagac tgcagctgat agaactgcat taatattgag
    32521 ataagactct gttgccttgc caggaccaat acaaactgct tcatctgcca acagcgtatg
    32581 aagagcttcc ttatcagcag ttgaataaac cgctaccgtc gcaatcccca attcacgtgc
    32641 cgcacggata atacgaaccg caatttcacc acgattggca attaaaattt ttcgaaacat
    32701 ggagaacctc cttagttccc aattgcaaaa gtaagggtac cactggctgc aagcttgcca
    32761 tccacttcag cctttgcttc aaccacagct atggtgccac gacgttttac aaaagtcgct
    32821 gtcataacca attggtcgcc tggtacaact tgcttcttga acttaacctt atccatacca
    32881 gcgtaaaaga ccagttttcc tttattttca ggttttgata actccaacac accagcagtt
    32941 tgcgccaagg cttccataat cagaacacct ggcataactg ggtattgagg aaagtggccg
    33001 ttaaagaaag gctcgttgat ggtcacattt ttgatagcaa caatggtatc ctcgctcacc
    33061 tccaagacac ggtccactag aagcatagga taacggtggg gaagggcttc tttgattcct
    33121 tgaatatcga tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt tcttcgttag
    33181 agacgagaat ttccgttacc acaccatcct taggagctgg gatttcattc atgactttca
    33241 tggcttcgat aattaccaat gtttgacctt ttttgacact atcaccaact gtaacgaagg
    33301 caggtttatc tggtccagca gccaagtaaa ccactccaac aagtggactc tctacaagat
    33361 ttccctcact agccacactt gcttcagctg gagctggaac ttcttctgct acagtctctg
    33421 ctggagcaga tgtaggagct actggactcg gtgttgctag aacgggtgct ggagcgactt
    33481 gagttgcaac ttcaggcaca ggtctcgctt cattcttgct aaactgcaac tcatccgtcc
    33541 catttttata agaaaattct ctcaaacttg actggtcaaa ttgagtcatc aagtctttaa
    33601 tatcgtttaa attcatactt atctattctc ccaacgtttg aaagcaagaa ctgcattgtg
    33661 gcctccaaaa ccaaaagtat ttgaaatagc gtatggaatt tctttctcca agccttgtcc
    33721 ataaacgaca ttagcttcga tataatctga tacttcactt gtcccagctg tcattggtac
    33781 aaagttatga cgcatagctt cgatggtgac gatagcttct actgcacccg cagcccccag
    33841 caaatgtcct gtaaaagact tggttgatga tacaggtact tccttaccaa gaacagctac
    33901 gatagcacca ctttctcctt tttcattggc aggagttgac gttccgtgag cattgacata
    33961 ggctacttgc tctggagaaa tctcagcttc ttccaaggct agtttgatgg ccttgatagc
    34021 tccctgacct tctggatgtg gagaagtcat gtggtaggca tcacaagtat ttccgtaacc
    34081 aaccacttca gccaggatag tagctccacg tttttcagcg tgttcaagac tttctagaac
    34141 caacatccct gaaccttcac ccataacaaa gccattgcga tccttatcaa atgggatcga
    34201 agcacgagtt ggatcctctg tagtagagag agctgttaag gcttggaaac cagcgatggc
    34261 aaaaggtgtg atagaagctt ctgttcctcc caccaacatc acatcttgga aaccaaactt
    34321 aatggagcgg aaggcatccc caatcgcatc atttgatgaa gagcaggcag tattgataga
    34381 tttacaaaca ccgtttgcac caaaacgcat ggctacattc ccagaagcca tatttggtaa
    34441 agcttttgga agagtcattg gtttgacacg tttgggtcct ttttcatgaa ggcgaagtac
    34501 ctgatcttca atttccttga ttccaccaat accagatgca acgataacac caaaacgatc
    34561 cctattaaga gcctctacat caagattggc atgatttaca gcctcttggg ctgcatacaa
    34621 ggcatataaa gaatagttat caaaacggtt ggtatctttt tttacaaagt atttatcgaa
    34681 cggaaaatct tggatttctg ccgcattatg cacatcaaag tcactatgat caaattttgt
    34741 aatgccacca atgccgattt ccccagttgc taaactattc caaaattctt ctggtgtatt
    34801 tccgattgga gatgttactc cataacctgt taccactact cgatttagtt tcattctttt
    34861 cacctctagc tttcgctaca tacttaagcc accatcaatg gcaaccactt gaccagttag
    34921 ataatcttgg cctgctaaaa atactgtcaa atctgcaacc tgctctgcct gcccaaattc
    34981 tttcatcgga atctgagcta gtgtagcttc cttaatctta tctgataaga tagctgtcat
    35041 atcagactca atcattcctg gagcaatcac attgactcgt atattccgac tagcgacctc
    35101 gcgtgccaca gacttggtaa agccaatcaa gccagcctta gaagcagcat agttagcttg
    35161 accaatattc cccatcaaac caacaacact agacatatta atgatagcac cttctctggc
    35221 tttcatcatc ggtttcaaga ctgattgtgt catattaaag gcaccagtca gattgacctt
    35281 gagcactttt tcaaaatctg cttctgtcat cttgagcata agagtatctt gggtaatccc
    35341 tgcattgttg accaaaacat ctactgaacc cagttctgca atagcttgat caatcatacg
    35401 cttagcgtct gcaaaatctg atacatctcc tgaaatggga accaccttga taccatagtt
    35461 tgaaaactca gcgagcaatt cttctgagat tgccccacga ctgtttaaga caatgttggc
    35521 tcctgcttga gcaaacttgt gggcgatggc aagaccaatt ccacgactcg aacctgtaat
    35581 aaagatattt ttatgttcta gtttcatttt tttcctttca aaacttctac ttattttagt
    35641 ctatttttct aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta agtgagcagt
    35701 ttgatcaatt tttttaacaa aacctgacaa gactttcccc ggtccaatct cgataaagtt
    35761 gcttatgcct gcttcttgca tgaccccaat actttcatag aaacgaacgg gttccttgac
    35821 ctgacgcgtc aagagctgag caatgtcctc tttttgcatc acagcagctt ctgtattgcc
    35881 gactagggga caagtaaaat ctgaaaaact tacctgagct agagtttcag ctagtttctg
    35941 gctagcaggc tcaaggagag cggtgtgaaa gggacctgac accttaagag gaatcaagcg
    36001 tttggcacct gcttcttgca aaagttcaac cgctcgatca actgcaacca cttctccagc
    36061 aatgacgatt tgtgcaggtg tgttatagtt ggctggagta accactccaa gttcagaagc
    36121 tttttgacag gcttcttcaa tgacctctac tggcgtattg agaactgcta ccatcttgcc
    36181 agagtcagca ggagccgctt cttccatata ggctccacgc ttagctacca aggcaaccgc
    36241 atcttcaaaa tccaaggcgc cgcttgccac caaggcagag tattctccaa gagacaaacc
    36301 agcaaccata tcaggctgat agcccttttc ttgcaataaa cggtagatag caaccgaagt
    36361 cgctagaatg gctggttgcg tatagcgggt ctgattgagt ttgtcttctt ccgtatcgat
    36421 gagataacgt aaatcataac cgagcacctg actcgctcga tcaatcgttt ctttgacaat
    36481 cggatactga tcatagaaat cccgtcccat ccctagatac tgggcacctt gaccagcaaa
    36541 taaaaaggct gttttagtca tttcttacaa ctcctgccca gcgagaggct tcttcttgaa
    36601 ttttcttagc ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt tcttctttag
    36661 aaacaagccc tgcgatttga cctgccatga cagagccacc atccacatca ccgtgaacaa
    36721 ctgctttggc tagggcacct gctcccattt gttcaaagat ttctaaatca ggatcttcct
    36781 gcttaaaggc atctttttca gccagttcaa aatctctagt caactgattt ttaatagcac
    36841 gaacagcatg accaaagtgc tgagctgaaa tcgtagtatc aatatccctt gcttttaaaa
    36901 ttttctcctt gtagtttgga tgggcattcg actcttttgc aactacaaac cgtgtcccca
    36961 cctgtacagc ctctgcacct agcataaagc cagccgcagc accttcacca tccgcaattc
    37021 ctcctgcagc aataacagga atagatatag ctgtggctac ctgtcgcacc aaggtcatgg
    37081 ttgttaattt accgatatgc cccccagctt ccattccttc tgcaataaca gcgtctgcac
    37141 cgattttttc catgcgttta gctaaagcga cactaggaac gacaggaata acgattatcc
    37201 cagcttcatg gaaacgttcc atatacttgc ttggatttcc tgctcctgtt gtgacaactt
    37261 taacaccttc ttcaataacg agatccacga tatcttccac aaagggagat aagagcatga
    37321 tgttgacccc aaagggttta tcagtcaatg atttgatttt atcaatatta gccttgacaa
    37381 cttctttcgg ggcatttccc ccaccgataa ttcctaatcc tccagccttg gaaacagccc
    37441 ctgccaaatc accatcagca acccaggcca tccctccttg gaaaatagga tagtcaatct
    37501 tcaataattc tgtaatacgc gttttcatag tgcctccaac cttccttgct tacgtaatag
    37561 ttcgatttca ccataatttg acagtcaaac tattacctaa acaagaggga gtgggtttct
    37621 ccctactcct tctactaata ttctgcttat tttgcttgct cttcaacgta agcaaccaag
    37681 tcaccaactg ttttcaagtc attttctgct tcgatttgga tatcaaaagc atcttcgatt
    37741 tctgagatta cttggaacaa gtccaatgaa tctgcgtcca aatcatcaaa agttgattca
    37801 agtgttactt ctgatgcgtc ttttccaagt tcttcaacga taatttcttg tactttttca
    37861 aatactgcca tgataggact cctttaaaat aaatagtttt tttataacaa tgtgttcacc
    37921 acatgattac ctaaattgta agaatgagcg tgccccaggt caagcctcca ccgaagcctg
    37981 atagaagaac agtctggcta ccatctaaag ggatgagacc ttgttctaca cactctgaaa
    38041 gtaaaatcgg gatactggct gcactggtat tgccatattc catcatattg gctggaagtt
    38101 tggctcggtc aacaccaatt tttctagcca tcttatccaa aatacggtca ttggcttgat
    38161 gaagtagcag ataatccaag tctgtcacct ctataggaga ttcatcaata gtctgcttga
    38221 tagacttggc tacatctcga atggcaaaat caaagactgt gcgtccatcc atcttcaaaa
    38281 acgaatctgc actttcttga tctgaaaatg gagaatgcaa acctgaatgc ccataagtta
    38341 aacactcact gcgacttcca tcgctattga ggctctcagc taagaaatgc tcttgctcgc
    38401 tagcttctaa caagacacca ccagcaccat ctccaaacaa cacagctgtt gatcgatccg
    38461 accaatcgac tgccttagag agggtttcac taccaatcac caagcctttt tgaaagcgac
    38521 cagaagcgat aaacttttca gcagttgaaa gagcaaatac aaatccactg caagccgcgg
    38581 ttaagtcaaa agcaaaggct ttattagcac caatattagc ttgaacacga gcagctgtag
    38641 agggcatcat cgaatctgga gtaatggtag ctaggatgat aaaatccagc tcttctcctg
    38701 ttattccagc ttttgccatc agtttcttag caacctctgt agccaaatca ctggtagatt
    38761 ctgttcttga aatatgcctt tgtcgtattc ccgttcgact tgaaatccac tcatcattgg
    38821 tatccataat ctgagccaag tcgtgatttg taaccacttg ctctggcaca taatgagcaa
    38881 cctgacttat ttttgcaaaa gccattattt caaatcctcc aaaaattggt aaagattagt
    38941 caagccttta cccatgacag caatttcttc ctcgctcatg ccatcaataa ttttttctac
    39001 catggccttg tggaagcgtt tatgcagtct atgaatcaag cgacccttct ttgtcaaatg
    39061 cagatgcacc acacgacgat cctgttctga ccgaactcgc tcaatgtagc ccttacgctc
    39121 taaattgttc aaacttgtcg taacagttcc aagagttacc atcaactctt ttgacacttg
    39181 acttggagtc acatctggag ccttaccgat gacatcaatc gtatgcattt ctttgatgga
    39241 gatatcctta aaacgactac ctctcaagtt cacttcctca attacaagga cattgttaaa
    39301 tatagatgtt aaatattcat tgattcgttg gtagtccatt tttcatatcc ctccttcttc
    39361 aaaaaacttt tacaatcaaa acatttgaca gaaagaatta tatcaaaatt caaagaatga
    39421 tgcaagtatt ttttattttc ctgtaaattt aggtcttctt ctctccgaat gagctcgcac
    39481 tccttctttg aaatcctctg tttgagctaa ggatttctgt aggttcaatt ctaaagtagc
    39541 gtaaccctgc cagtctttaa attggctctc ccaaaccaac ttcttaatgg cagcatagga
    39601 attacttgaa gcacgtctta attttttaag aagctgttct ctcgtctttt caagtttttc
    39661 agcttcagaa acgcggtaaa ccaaccccca ttctagggct ttttctgccg ttaaagcctc
    39721 tcctgtcata gctaattgag cagcacgcgt cacaccgata ctgcggctca agagatgaat
    39781 tccccctgca tctggagcca aaccaacacc aacaaaggct tggataaact tagccttatc
    39841 cgtcgccaaa cagaaatctg ccgcaacagc catattcgct gcggcacctg caacagcacc
    39901 gtcaacttcc attaaaacag gtttggctat ttgcttgatt ttataagaaa tcgtattgac
    39961 caactctgcg atttttgtca acgatggaat atcatcctca tccactgctc gcttcatctc
    40021 taccaaatct cccccaactg agaagacctt tccattggca ttgattaaga taaaatgcac
    40081 agctggattt tcttctgcca aagtcagagc ttctaaaatc tcctcacaca tgggaatatg
    40141 aaaaccattt gcgacctcag gacggttcaa ggtaaggatt gccaagtcct cttcaagctg
    40201 ataaataatg tgttccatca gggctccttt ttattttata agcagtttat actcttcgaa
    40261 aatctcttca aaccgcgtca gcttccatct gcaacctcaa aacagtattt tgagctgact
    40321 tcgtcagtct tatttacaac ctcaaagcag tgctttgagc agtctgcggc tagcttccta
    40381 gtttgctctt tgatttcatt gagtgttaaa ttatttcact gtcaaagtat atctttttta
    40441 ggagcagaaa gcaagaaaaa atcgactgaa agtgtctcag ccgataagaa aggctcgctt
    40501 taggctagaa agcatcttat tttcttcatt gaaaaaagcc tttctttctg ctataatcgt
    40561 ataaaatact tactttagga gttcttatga aagttgttaa atttggaggt agttctcttg
    40621 cctctgctag tcaattagaa aaagttttaa acatcgtcaa aagcgattca gagcgtcgtt
    40681 ttgtagtcgt ttctgcgcct ggtaaacgca atgctgaaga tactaaggtt acggatgccc
    40741 tgattaaata ctaccgcgac tatgttgcgg gtaacgatat tagcaagagc caaagctgga
    40801 ttatcgaccg ctatgctgct atggttagtg aattgggact aaaaccagct gtgctagaaa
    40861 aaatttctaa aagtattcac gccttggcca ctcttcctat tgaagaaaat gaatttctct
    40921 acgatacttt cctagcagcc ggtgaaaata acaatgccaa attgattgct gcctacttta
    40981 accaaaatgg tatcgatgca cgctatatgc accctagaga agctgggatt gtggtcacaa
    41041 gtgaacctgg tcacgctcgc atcattccat caagttatga caagattgaa gaattgacaa
    41101 acaccaatga agtccttgtc attcctggtt tctttggtgt cactaaggaa aatcaaatct
    41161 gtactttctc acgtggaggt tctgatatta caggttctat cattgctgct ggtgtcaaag
    41221 ctgacctcta tgaaaacttt acggacgttg atggtatctt tgcagctcac cctggtatta
    41281 tccaccaacc acactcgatt cctgagttga cctaccgtga aatgcgcgag ttggcctatg
    41341 caggcttctc agtccttcat gacgaggctc ttcttcctgc ctaccgtgga aaaattcctc
    41401 tggttatcaa gaataccaac aaccctgacc atccaggtac tcgtatcgtt ctaaaacaca
    41461 gtaatgatga atttccagtt gtgggaattg ctggtgactc aggctttgtc agcattaaca
    41521 tgtcgaaata cctcatgaac cgtgaggttg gatttggccg caaggttctg caaatcctgg
    41581 aagaacttaa catcggttgg gaacatatgc caacaggtat cgacgatctt tctatcattc
    41641 tccgttctcg ccaactaact cccatcaaga aagaagaaat cctgcgtcag ttggttcaaa
    41701 aggctaaagt agatcatgca gaaatcgaac acgacctttc tatcattatg attgttggtg
    41761 aaaaaatgaa gagccatatc ggagtgactg ctactgcgac acgcgctcta tctgaaaaca
    41821 aaatcaacat ccagatgatg tctcaaggtt ctagtgaagt ttctattatg tttgttgtca
    41881 ataaagacca agagaaagca gcaattaaag ccctctacaa tgcctttttt ggagaaagta
    41941 aggaagacta agcatggctc aatcacttaa caaaacagta ctcctcagta caacaggcac
    42001 ttcctacctc tctatagctg ggaaagttgg gaaattcctt gtcggagatc aggctttgga
    42061 attttaccca gatgtcaatg tcgaacaatt tatccagatt ccttggagcc atatcaatca
    42121 gattggagcc aatgtcactg gacgcaaaat cagccgccac ttcgaagtct ttacagacaa
    42181 aggaaaattc ctctttgctt caaaagactc aggtgccatt ctcaaaattg cacgcaaaaa
    42241 actaggcaat gacaaggtcg tcaaacttcc gaccctgatt cagacaatta gccaaaaatt
    42301 taaaaatcta tttgcaaaaa agtagaaact ttagtataat catagcaacg gataagtagg
    42361 ttatcttctt ctttcagaaa gtctgcgggt actgcgagca gataggaggg ataggtgaaa
    42421 ttctaccgtt agtaacaatt acatacacaa tcaagtgcac acctgtgaag ttggatggaa
    42481 ccgtggccct gccactccaa cgttttgtca ggtgtgcttt tttcataaag gagttcttat
    42541 gttagatatc aaacgtattc gtacagattt tgaagctgtc gcagaaaaat tagctacacg
    42601 tggtgtagat gctgctgtct tgaatgaaat gaaagaaatc gatgctaaac gtcgtaacat
    42661 cttggtcaag gttgaaactc tcaaagcaga acgtaacaca gtttctgctg agattgccca
    42721 agctaagcgc aacaaggaaa atacagatga caagattgct gccatgcaaa atctatctgc
    42781 tgaggttaaa gccttggatg ctgaattggc agaaatcgat gctaaattga cagaatttac
    42841 aacgactctt ccaaatatcc cagctgacag cgttcctgtt ggggctgacg aagacgacaa
    42901 tgtggaagtt cgccgttggg gtactccacg cgagtttgac ttcgaaccta aagctcactg
    42961 ggatctcggt gaagaccttg gtatccttga ctgggaacgc ggtggtaagg taacaggcgc
    43021 tcgcttcctc ttctataaag gcctcggtgc tcgtttggaa cgtgctatct acaactttat
    43081 gttggatgaa catggaaaag aaggctatac tgaagtcatc acaccttaca tagtcaacca
    43141 tgattctatg tttggtactg gtcagtatcc aaaatttaag gaagatactt ttgaactcag
    43201 cgataccaac tttgtcttga ttccaactgc tgaagttcct ctggcaaact actaccgtga
    43261 tgaaatctta gacggcaaag atcttccaat ctacttcact gctatgagtc cgtcattccg
    43321 ttctgaggct ggctctgccg gtcgtgatac gcgtggcttg atccgtttgc accaattcca
    43381 caaggttgaa atggtcaaat ttgccaaacc agaagaatct tacgaagaat tggaaaaaat
    43441 gacagccaac gctgaaaaca ttcttcaaaa actcaacctt ccataccgtg tcgttgctct
    43501 ctctactgga gatatgggct tctcagctgc gaagacttac gacttggaag tgtggattcc
    43561 agcacaaaac aattaccgtg aaatctcaag ctgttcaaac acagaagatt tccaagcccg
    43621 tcgtgcccaa atccgttacc gtgatgaagc agatggcaag gtgaaactcc ttcatacctt
    43681 gaacggttct ggacttgcag ttggacgtac agtggctgca attcttgaaa attaccaaaa
    43741 tgaagatggt tctgtgacca tcccagaagc acttcgtcca tacatgggtg gagctgaagt
    43801 catcaaacca taaaaaataa ggtttagcta tttctagcta gacctttttt cgtaaccaaa
    43861 tcagataagc acctagtaca aagaataaaa tagttaggca tataacggtt tcagccaata
    43921 ccaggtaatc cagaaatgga agtttcaaaa ttccctgagc catcttgagc gaggtcgctg
    43981 tgataatggt tgggaaggtg agggctgaga aggctggttg aaaaccttgt tttaaaatgt
    44041 tgggcagacg agttaaaaca aagaaaaaga aggattgaga agccaaaatc atgacaatca
    44101 agacccaagt cggcaggctg gttcctccta ctcgaactag agaagccaag agtagagaga
    44161 aaggagcaca gtagattcct tcttgtccaa gcaaggctag tgggagtgga tatttcttta
    44221 aatcgctata aataagggga tagagataga aggtcaagag aaaaccaaaa ctcaaggtcg
    44281 cataggcaat ttcgataata cctaccagag gataggtcaa ggcagccact gctatcccca
    44341 catagagaac cgtccaactt ggagtggcat gaaccctccg ccctggacaa gcaaacttga
    44401 tggtaaaacc agcaatcaag gtcaaatcca agagaaatga aaaccaccaa atcccttgtg
    44461 ctaccaaagg aagataagag aatacgcgaa agacataggt cgataaaatc atcccagcca
    44521 taggaaaggt tgccattcct gacaaaagag ggggcttggt caattcttgc ttggtttctt
    44581 tccaattaaa gagatgcaga attagaaagt aaatccataa aaccaaacca gtcagactaa
    44641 aaagatggga tagaaccggc aacgtatcta aaataagatt tccagctcct gccaaaccta
    44701 gcaaacaacc tgaaaatact aaggggagtt ttttcatcct aacctccaat aatcatgtta
    44761 gtttcagtat aacataaaag cgcttaaatg aggatttaaa aaacgaagtc cgcttatttc
    44821 agacttcatt ttactcagat atgaattagg cataaggttg caattctgga ttaattggtg
    44881 tattagctaa gttgttggca tagttacaga ggattgctag gctgacacca aaaaccacat
    44941 ccaaggcatt ttgttgagtg tagccagctt ctaaaaactc agacaaggct tcatctccta
    45001 cacgaccctt ggtattgata actgccaagg taaacttagc tagggtatcc aatttaggat
    45061 ctgtttcaat tggagtacga ttgcgaagag cttgaatcaa gtcatcattc atctggattt
    45121 gtttgatgga aaaggctgtg tgacctgcga cacagaaggc acaaccattg gtcacggctg
    45181 ccgtgatttg caccacttca cgctcaacgg gtgtcaggct gttgcgacgg tggatagatg
    45241 agacaatttg ataggcttct aaaacagtcg gggcattggc caagagaccg attaggttgg
    45301 gaatatagcc attgttgtct ttttctactg tttcaagaat ttctttcact tctgctggtg
    45361 ctgactctac tgtatggata gtaaatgttg tcataagata cctcttttct tattattgac
    45421 actaatatta ttggaaaatc ttataaaatc ctgattccta agtttatcta agataaagct
    45481 ttattctctc ataagatttt cgttgttata ttagtttatc acacttccaa tcacttgcat
    45541 aatatatatt atatatcagg ctgataaaaa ttatttatag gcaaaaaaat cacacgagct
    45601 gtgtgattcc attatttgtc aaaatacttt ttagtttcag caataacgac tggcgacaag
    45661 accaagaggg caatcaagtt tggcagagcc atcaaggcgt taacgatatc tgcgataatc
    45721 cagaccatat ccaactcgat aaatcctcct aacaagacca tgagcacaaa aaacacacgg
    45781 tagagccaga taaagcgagc cccaaagagg aactcaaaac agcgttctcc gtaatagttc
    45841 caacctagaa tcgttgtaaa ggtaaaaagt acaaggaaga tggtcaagag ggcaggccca
    45901 aagtgtgaaa agactgttga gaaagctgac tgagtcaagg caaccccatt caagtcacca
    45961 ctccaaactc cagttaccaa gatggtcaaa ccagttagag tacaaatgat gagggtatca
    46021 ataaaggttc ctgtcatgga aatcaaacct tgctctactg gttcatttgt cttggcagct
    46081 gcagctgcaa taggagcaga acccagacca gattcgtttg agaacacacc acgcgccaca
    46141 ccattttgaa tagccatccg aacgctagca ccagcaaatc cacctaccgc agcaagggga
    46201 ctaaaagctg aggtaaagac taaagcgatt gtgccaggga tttttccgat attaaagaaa
    46261 ataactgtaa gagttcctaa gatataaatg agggccataa aaggaacaac agtagttgaa
    46321 accttagaaa tagacttgag tccaccaaag actgcaatcg ctacaaagac agacaagacg
    46381 agagctgtga tggctggcga aatcgtcgtt gtattttgga tagattctgt aatcgagttg
    46441 acttgggtga aggttccgat tcccaagaga gcaaccaata ctcctgctac tgcaaacaaa
    46501 acagcaagtg gtcgccactt ttctcccatc cctagaagga tatagtgcat gggacctccc
    46561 gctactgcac catggtcgtc cttggtgcgg tatttgatgg ccaagagtcc ttccgcatac
    46621 ttggtagcca ttccaaagaa agccgccatc cacatccaaa atagagctcc tggtccacca
    46681 accttgatag ccgtcgcaac tcctatgata tttcctgttc caacagttga tgccaaggct
    46741 gtacacagag ctgcaaaact ggatacatca ccatgtccct tatcctggat aaaaataagc
    46801 tgaaaggcct tgggcagacg caaaacctgc aagagtccta gccgcatggt taggtaaatc
    46861 cctgttccga ccaataaaat caagaggggc ggtccccaag caaaagcatc gattgattta
    46921 agcaattcta acatttcctt ctcctatcgt ttcaacccca aaagaaagag cacatgcaag
    46981 atacatgtac tctggaatgc ttagataaat gctaaaaagc ggtctatcct agctctgtcc
    47041 ttttacctga gagtttgagc agttgcctgc cttgcccctt cggtgccttt acggtctctc
    47101 cagagttccg tccatttaca gtcatggaaa atcaaacgat tccccacttc tattaaactt
    47161 cattcggtgt tggtatttaa ttgattctaa ttttacaaaa aatgttggct tttgtcaatg
    47221 tgtttattag taaaaattag ttcaacagtt tttactttat aaagtccaga atactgctat
    47281 cctttaaaag tgacaatagt cgcaccactg cctccagcat tttgtggggc atagccgaaa
    47341 ctcttgacat gtttgtttct ttgcaagtat ttggtaactc cttcacggat gactcctgtt
    47401 ccgataccat ggatgatatc aacttgagcc atattgttaa gcaaggcttg gtcgatgaag
    47461 gtatctagct cattcatggc ttcttcatag cgcttgcctc gaagatccag tctagcttga
    47521 ggtcctcgcc cagaagttcg tttcacaaca ttgacctgtt tcttcttgac tggtttttct
    47581 tgctgggctt gaacaagatc aaactctttc tcttccaagg tcatcttaat caagccaact
    47641 tgggcttccc agcggccgtc cttaagttga ctggtcaagg taccacgctg accataactg
    47701 agaaccacga tatcatctcc cacctttgga gctcgttttt tcttggcctt ttgaaggacc
    47761 ttgtttttag acaagtccac tttttcagga gccaattttt tcaacttggc tttggcttca
    47821 atgatttcgt ggggcttgag ttgggattta ctgtggagat ttttgagaat ctggtcactt
    47881 tcacttaggg ccatatccac aatctcagca gcctgttcac gcgccttgtt aagctcggtt
    47941 tccttttcac gattaagctc gttgtagagt ttttttagca cacggttcat cttgagattt
    48001 tcttgctcca cctcacggat attgtccaag cgtttgcggc tttccagcgt ctgctcttct
    48061 agttgctcaa tgatacgatt gacgtcattg tcctgatcga tctgctgact ggcatctcct
    48121 acgataactt cagataggcc tagacgtttg gcaatttcaa aggcattact tcggccagga
    48181 acaccctgca taaagcgata ggtcgggcga agagttgcag tatcaaactc catactggca
    48241 ttttgcacaa aggctgtctc aataccgtag gccttgagtt ctggatagtg ggtcgtcgcc
    48301 atggtcttga tttgacgcag gcgaaggtcc tccagaatag ccatggcaag ggctgctccc
    48361 tcttggggat cagtaccagc ccccaactca tccaaaagta agagtgaatg ttggttgacc
    48421 ttgccaagaa tatccacgat attggtcata tggctagaga aggtagacaa gctctgctca
    48481 atagactgct catctccaat atcagcaaag atttcttcaa aaataccaac acgacttccc
    48541 ttgtctgcta aaatcggcaa tcctgactgg gccatgacct gtgtcaagcc cagagttttg
    48601 agcatgatgg tcttcccacc tgtattggga cctgtaatga caatagctgt taaatcttga
    48661 ccaaaataga catcatttgc gacggcattt ttgaccaaag gatggcagac atggagcagt
    48721 tgaatctctt gattttctga cagctgaggc acgactgctt gtctttcttg gataaatcga
    48781 accttggcac gaatcaagtc cagatgaccg ataatccaag cgtcattagc aatctcagcc
    48841 gcatgagggc ggacacgctc agaaatttct tggagaatgc gaagcatttc atagcgctca
    48901 tctgctcgca gactagcaat ttcttcgctc agtttgacta cctcacgtgg ttcgatatag
    48961 acggtgtttc cactagcaga aatatcatga acgacacctg caatcttatt gcggtaggtg
    49021 tttttgactg gtaaaacctg acggccattt ctgctagcaa caattccttc cgtcaacatc
    49081 tgcgcttttt gcttgagcaa gtcttgtaaa acatcgcgta cctgactctc gctatcatgt
    49141 atttttcgac ggattcgcgc caattcttca ctggcaaaat tttcaatgaa acccgcatca
    49201 ttaaaggcct gaagatttcc ttgtaattgc ggaaaatcat gtaatttctc aaaccaaagg
    49261 gctaattctt ccaagctgac attttccaga ttggcgtaaa aactttgaag ttctcggctg
    49321 gtaagaagca cgcgtttcaa gagtaggaac tcctcgatat tgagatccgc tcccatctcc
    49381 aacctcttgc agactcctgc aatttcctta gttgagagaa tagtaaaatg cggttgctcg
    49441 acgaaaagag cctgcatttc tttcatctca gcaaaagcct gtttgatttt atctgctttg
    49501 gcagtcggag ccagctgtct caattgctcc aagccctgct cggtcaacaa atgaggctca
    49561 aacaaggcct tgatcttatc gaactctaat gtttctaata ttttcttatt catctttatt
    49621 tccttgtctt tgaatgtcta ggtgtggtag ctttttacat tctgatagat tcgagtcaaa
    49681 tctgtaaaca aagggctagg aaaactcctg ccctttttat ccgattaaat ttgtcaccca
    49741 gatttgtttg agccaactgg ttgttatcgg tatgctctgg atgatgtgtt ttgcgacgat
    49801 actcttttca agaggatttt gtataactgc catggggatg gtcgccaaga ttgtcaaggc
    49861 catttgcaag acaaataagg tcaccaacat ggacaagata cctgctgaaa cttggaacaa
    49921 cttaccaccc agttttttgc taggaatcaa gtgtaagaga agaccaagca aacgaccaat
    49981 gctatagaca atcccaaata caagcaagta gccgatacct gcataaaaga ccttatccag
    50041 ctgaaagagt tgatccgatg ggaaaaagaa agtcccctga ccttcctgcg aatttgcata
    50101 agggagcaat aaatggaatt gctctccaag ccccttataa aactggccag ccataaaagc
    50161 cgatgccatg gctgaaatca ggtaataaac ctgtaagagc aggcctctcc gatagccgat
    50221 ataaaatccc caaaccaaga ccaatagaag aaggaatgaa atcataagga atcctcaatc
    50281 ttgctctgtt cttgcttaca agtcacaagc ttgtgacgga gttcttctag ctcttgctcc
    50341 ttatcgtcaa attcaatctc acggctgagc tgagttgata aacagttgac tgccaacaaa
    50401 agagcgattg tttcatcatc tgcgctaggc atttgttctt taattgcttg gtatttttct
    50461 gtcgcaacct tagcgatttc ctccataaaa aggttatcat gttcgcttgt caaggttaac
    50521 gattttttcc cgaatgtaaa tttgaatcga tttagatttg ccataaaatt cacctcacga
    50581 tattatacca aaattcgcta attttgtcag tttttacaaa ttttactgct tttgtggtac
    50641 aatagaaact atggcaagta tcacactcac accaagcgaa aaggatattc aggcttttct
    50701 tgaacactat caaaccagtc tggctcctag caagaatccc tatatccgct actttttgaa
    50761 actacctcaa gcaacggttt ctatctatac ttctggaaaa atcttgcttc agggtgaagg
    50821 ggctgaaaaa tacgccagtt tctttggcta tcaagctgta gagcaaacca gcggacaaaa
    50881 tcttccttta attgggacag atgaggtggg aaatggttcc tactttggtg ggcttgcagt
    50941 tgtggctacc tttgtcacac ctgaccagca cgacttttta cgaaaactcg gtgtggggga
    51001 ttctaagact ctgaccgacc aaaagatccg tcagattact cctattctca aggaaaaaat
    51061 tcagcaccag gcactccttc tctcacccag caagtacaac gaggtcatcg gagaccgcta
    51121 caacgctgtt tcggttaagg ttgccctcca taatcaggct atctatctcc tccttcaaaa
    51181 aggtgttcag cctgagaaaa ttgtgattga tgcctttacc agtgctaaaa attatgacaa
    51241 gtacttggca caagaggcca atcgtttcag caatcctatc agcttagaag aaaaggctga
    51301 gggcaaatac ttgtctgtcg cagtttcttc tgtcattgcg cgtgatctct ttctggaaaa
    51361 tcttgaaaat ttgggacgag aactgggtta tcagctccca agtggagctg gaacggcttc
    51421 tgacaaggtg gctagccaga ttttgcaagc ctatggtatg cagggactca gcttctgcgc
    51481 caaattgcac tttaaaaaca ctgaaaaagc gaaaaaacgc ttagaaaggt aagttatgaa
    51541 ttcatttaaa aatttcttaa aagagtgggg attgttcctc ctaattctgt cattactagc
    51601 tttaagtcgt atcttttttt ggagcaatgt tcgcgtagaa ggacattcca tggatccgac
    51661 cctagcggat ggcgaaattc tcttcgttgt aaagcacctc cctattgacc gttttgatat
    51721 cgtggtggcc catgaggaag atggcaataa ggacatcgtc aaacgcgtga ttggaatgcc
    51781 tggcgacacc attcgttacg aaaatgataa actctacatc aatgacaaag aaacggacga
    51841 gccttatcta gcagactata tcaaacgctt caaggatgac aaactccaaa gcacttactc
    51901 aggcaagggc tttgaaggaa ataaaggaac tttctttaga agtatcgctc aaaaagccca
    51961 agccttcaca gttgatgtca actacaacac caactttagc tttactgttc cagaaggaga
    52021 ataccttctc ctcggagatg accgcttggt ttcgagcgac agccgccacg taggtacctt
    52081 caaagcaaaa gatatcacag gggaagctaa attccgcttc tggccaatca cccgtatcgg
    52141 aacattttaa gaaacctaag aggccgagaa tcaccaatct cagcctcttc ttctatcgtg
    52201 agaaaatgat tggtaactat ctaaacttac cagaacagaa acacctcaac tctcacctat
    52261 tcatgcaaag gaattttatg gaagtttatt tttcaggaac tattgaacgg attatttttg
    52321 aaaatcccag caatttttat cgcatcctcc tcctagaaat cgacgatacg gacgcagagg
    52381 attttgatga ttttgaaatc attgtcacag gaaccatggc tgatgtaatt gagggcgaag
    52441 actatacttt ttgggggcaa attgtccagc actccaagta tggagaacaa ctgcaaatca
    52501 gtcgttatga tcgcgcaaaa ccaactagta agggcttggt caagtacttt tcaagtagcc
    52561 atttcaaggg gattggtctc aagacagctc agaaaatcgt ggatacctat ggcgaaaata
    52621 ccattgacga aattttgcaa cacccagaaa agttagaagg catcgcagga ctctctgcca
    52681 aaaatcgcga ggctttcgtc tccactctcc gtctcaacta cggaacagag atggttttgg
    52741 ccaaactagc caactacggc attcccaaca aactagcctt tcagattcaa gacttttaca
    52801 aggaagaaac ccttgatgtg gttgaaaatt atccctacca gctggttgag gatatcaagg
    52861 gtttgggctt taccattgct gaccaactag ctgaggaact aggcatcgaa agtcaggctc
    52921 ctgaacgctt ccgcgccggt ctagttcaca gtctttttca ggcctgtatg gaaacaggag
    52981 acacctatgt tgaagcacgg gatttgctgg aacaaaccct tactctcctt gagtcttccc
    53041 gtcccgtgga actagacccc agccaagttg cccaagagct ctcctacctg atcgaagaag
    53101 acaaggttca gcagattgat accaagatct ttgacaacag cctctttttc gctgaggaag
    53161 gtatccgcag tcacttgatt cgtatccttg aaaaaggaaa acagaagagc caagatttag
    53221 aaactattca aaagcatatc actactgtcg agcaagaact ggggattgag tatgataaca
    53281 ttcaaaaaca agctatttgt gacgctatcc agaacaaggt ctttatcctg acaggtggac
    53341 ctggtactgg taagacaact gttatcaatg gaatcatcgc tgtttacgcc ctgttagagg
    53401 gacttgacct caggaagaaa agcaacctgc ccattcttct tgctgctcca actggtcgag
    53461 ctgctcgtcg catgaatgaa ttgacaggtt tgcctagcgc gaccatacat cgccacttgg
    53521 gaatgacagg tgacgatgat accagtcatc tggaagatta cctagatgct gactttatca
    53581 tcgtggatga attctctatg gtagatactt ggctggccaa tcaactcttc tccaatatct
    53641 cttctaacag taagatcctc atcgtaggtg acagtgatca gctaccttct gtcagtcctg
    53701 gacaggttct agcggatctg cttcatattc ctttgattcc tcagactcgc ttggaaaaaa
    53761 tttatcgaca aagcaaagaa tcaaccatcg tcaccctagc tagtcagatt cgacagggca
    53821 tcttgccagc tgatttcacc caaaaaaaag ctgaccgttc ctactttgaa attgctagtg
    53881 gccatattcc tgccaccatt gaaaaaatct taggtgccgc cctcagaaat ggtattcctg
    53941 cccgtgatat ccaagttctg gctcctatgt accgagggac ggcagggatt gatgctatca
    54001 atcagctcat gcaagacctg ctcaatcccc cacaaaaaga tcaactcagt tttgaagttc
    54061 ctcagtgcca ctatcgtaag agagacaagg tcattcattt ggttaacgat gctgaaatca
    54121 atgtctttaa tggagattta ggagctatca cagacctgat tcctggtaaa tacaccgaat
    54181 cgaaacaaga cgagattgtc attgattttg atggtaatga agtctcttac ccccgtaacg
    54241 aatggtacaa gattcgcttg gcctatgcca tgagtattca taagtctcag ggaagtgagt
    54301 tcccagttgt catcctaccg attactagtg ctagccgacg tatgctggag cgaaatctca
    54361 tctacacagc cattacacgt gccaaaagca aactcatctt actaggcgaa ttacaagcct
    54421 tcgactatgc tacccaacac atcggaactg cccgaaaaac ctatctgatt gaacgcttca
    54481 gtgatctact ggagaatgtt gaagaaaagc aacaagctgt ctctgaaaca gtcacatcaa
    54541 gtgcctctga acaatcctac atcctaaccg aagaaaactg ggacagcatt ccagccatga
    54601 ttgggattac agacacagac ctcaaagaga tttttggaaa atagtacatc agaaaaccca
    54661 ccaattcagg tgggttttct gtttattaag attattttac tgttgctgtg cttgtgatca
    54721 attcaacagc ttttttgata gtgatatcat gtttcaacat gtcagctgaa agcaagtttt
    54781 gaacttgtgc aacttccatg ttgtagtctg ctgccaattg ctcaacttct ttttggattt
    54841 cttcttctga agcatcaaat ccttcagctt tggcaactgc ttcgataaca aggttagtct
    54901 tagtacgtga ctcagcttct gcttggtatt ggttgtgaag gtcttcttga gtagttccag
    54961 tgatttggaa gtacatgtca gggttgatcc cttgacgttg caagttccca aggaattcat
    55021 ttactgaacg gtgaacttct tcatggatca tttcttctgg aagttctacg atttcagcgt
    55081 tttctacagc tgtatcaatt gctgcacctt caactgcatc tttgtaagct tcttctttag
    55141 cagtagccaa ttctttgcgg tatttttctt tcaagtcagc aagtgtttca acttcttcat
    55201 caatgtcttt tgcaagttca tcgtcaagag ctggaacttc tttagctttt acttcgtgga
    55261 tagttgtcac gaatttagct tctttacctg caaggtcttc tgcttggtag tcttctggga
    55321 atgttacgat aacatcaacg gtttcgccag ctgagtgacc taccaattgg tcttcgaaac
    55381 cagggatgaa ttgacctgaa ccaagtccaa gtgagaagtt ttcacctttt ccaccgtcaa
    55441 attcaacacc gtcgatagaa ccaacgaagt cgatcacaac agtgtcgccg ttttcagcag
    55501 cagcttcctt gataaccaat tcagccagat tgttgcgttc gcgttcgata cgctcttcaa
    55561 catcagcgtc agttacttct ttttctacat caactgatac ttcaaggttt ttgtagtcac
    55621 ccaattttac ttcaggtttt gtaacgactt cagcagtgat aacccagtct tgaccttttt
    55681 ccattgaagt tacgtcaatt tttggttggg caaccacttc aagaccagct tcttttacag
    55741 ctgcttcata agcgtttggc aaaagagcgt tcataacgtc ttggtaaagt gattcttcac
    55801 caaatttttt atcgaagata ggacgtggaa ggtgaccttt acggaaacct ggaacattaa
    55861 gagatttctt cactgacttg aagacacggt ccaattctgg tttgatttgg tcttgagaga
    55921 tagtgaaagt caagacacca cggtttgttt ctttgttttc aaatgataca gacattctgt
    55981 catttctcct taaaattttt taaatacagt ctattataac attttctata aataaaatct
    56041 agactaatgc agacaattat agacaacaag cctttttcct aactaaaaca ctcataaagt
    56101 atagacaatt ttagactact ttggatatct tttggttagt cattttccaa aactaattta
    56161 tctaatttat ctaatttttc agttatataa tagattgaaa ctagaatagt acacctctac
    56221 ttctaaaaca tttttagaaa tcgatttgac tatcctgatc gatttgtcct gttcttgttt
    56281 catttcacta tatagatcgc attcgaaaga attcgttcca aaattgcttg gttcgttctt
    56341 ctcttggacg actaaagaat tgatgggcat tatttttttc aacaattttc ccactgtcca
    56401 taaaaataac atgatgggct acatctctag caaaaactat ctcataaagc tgatcaaaaa
    56461 ctcaatctga ggagaaaatc caataaggct ttccataata aaggacatcc tatcaagatt
    56521 tttgaacacc cgataggctg cctttttccg attttgaaga ctttttgtcc agcttctttt
    56581 accttataaa taacaacaaa aatcaaagac aagctagaaa gattaccgca gataactcaa
    56641 acagtgtttt gaggttgcag ataagactga cggagtcagc tcaaagcact gctttgaggt
    56701 tgtagataga actgacgaag tcagtaacat atgcctaaga caaagcgatg ctaacctgat
    56761 ttgaagagat tttcgaaaaa tattaaatat actctacaat ttgatcaatc aattcttggt
    56821 cgtctaaacc tgtaacttgt ataacaacat ctttgactga ttgtttagcc aacaattcac
    56881 ctaatcgaat actttcttca tcatttacat cgcgatagtc aaaggcatag ccaactgttt
    56941 taagtaggtt tttatatgac aaactgagtt ctttcaattc acgtatcggc cggatgaatc
    57001 gttcattata gcctaatttt cggattggag tacgagctac gcgactaacc tcgtccacta
    57061 tgaaagggtt ttcaaaccgt tctataatga ctttgtgata attctccaat tcttttttat
    57121 caaagttcca tttggcaatc aagagactcc gaatttcagc taatacagat tcaatccgag
    57181 atttaatatt aggattttga agagcttcca aaattgtctt ggcaccataa tgcgcaccaa
    57241 tgtaagctga agttgcatgt ccagaattga ctgaaaaaag ttttcgctca ataaagggtt
    57301 ctaaatcttc ttcataatgc acatctttta gacgtaaatc tggattttta agacgcttgg
    57361 tttccacgac ccattcatta aagggctcga ccacaacaaa aagggaatct tcgtgacttt
    57421 gtgctggaac aatcctgtct actgcagcat ttggaaaacc tatgtagtta tcagcaaatg
    57481 tcaaaccttc cggacttaaa tatttcttga cttcttgata aagaaattga gacccgccaa
    57541 tcatattttc acaggccata acatccaatg cctgtgtatt tcctgcaact cggcgagctt
    57601 cgattccttt ggctagaagt tcggcgataa aagggagtat attaggtccg attgcagtag
    57661 taataatatc cgtcctttga atcgcttcaa tgacttgctc aggatgttct ttgctattaa
    57721 tgccagccac attagttact tctatacgag actgtccttt ctgtgcaatt tcaatttcat
    57781 acttgccctt ttcatttaga gcatgaatta tctgattatt gacatccaca aaatcaatat
    57841 ggaaaccatt tttaaataga atttcaccta taaaaccacg accgatatta ccggcaccaa
    57901 aatgaacaga atgtttcatt caatttctcc ttttcctatt tgagggacat atatactaga
    57961 tgacaaatga cgaaattcaa ttattcaaca gcatcaaata agcgcaatac ttcctctttt
    58021 gactgagcat ctgctagttt aagaacatta tctacatctg cacagaagat agaaattttc
    58081 tgaataattt ctaagtgttc attaccaata ccagcaatac caaaaagaac cgttgccact
    58141 tgagggttag atacattccc aaaatcaacc cctctaggga cttgaacgac tgtaatacca
    58201 gacttgagga catccttttt tgctgcatct gttccatgcg gtatggcgat aaagttaccc
    58261 atgtaaacag ataactcttt atctcgctca atcatggctt caatatagtc ttcattaaca
    58321 tatccaccct cataaagaac ttgcccacaa taacaaatag cttcctcctt gttagaaaat
    58381 tgtttattaa gcttaatcaa atgtttttca agtttcatat tagttctcca atttcttaat
    58441 tttttcgtta aaaatagtat ttagcatctg ataaataatg gattgatttc ccgtcttgta
    58501 aatctctgta taaagatgat tttcaataat cgactgacta atagctgtca ttaaatctct
    58561 agcttcctcg ctagcttctt tagacattag cattagcaga caccttttga cctcttcttc
    58621 ctctcgtttc attgacaatg cggagatagg tagtttgagt tcaaacatag taaaactatt
    58681 tgttgttact ttgctagact gactatgtaa aagcaccaga ccagtattag gaatagccat
    58741 aggactattc tggaagtgag ataacaattt tcttgttagg taatctctgt cactcacatt
    58801 cttctgatat tggatgattt gttctaccgt gtgctcaaat gattgattat tctccaattg
    58861 aaccaactcg aattgactca aaagctgact actagatatt aaataatctt gcaagtcata
    58921 acttttctct ggagcgatag catcacgcgc gacaattgta cgatgtgcct gtacatactg
    58981 aagtcgttcc tgtaattcaa gcaattcttt gacggttgga aaactagaaa ttacatcgat
    59041 ttcctgatta gtcagcggct tggtagataa aatataatca tactgactga gatcaatact
    59101 gtggtaatct actagagact gaatatctat caactctaca aaaggagcaa cactcttaat
    59161 tttactgact aataaatctc tagtgacccg acgttcatcc gttaaaagca aaacacggac
    59221 tggataaatc tctggactac ggcctaagct agagataaaa tgtagggcaa tcatgccata
    59281 ctcatactct gtatgaagat atttcggaaa aatatcattc actaaaagac tgatgactgt
    59341 ataaagaaat ttattccttt caactaaaat ctggacagat tctggcaaat tttcaccctg
    59401 aaaaaggata gggacgccta aactgagccg aatatgatgg aaaagaaaat tgaataaaac
    59461 cttgtcctta aaaaagtcaa ttttgatata catggaaacc gtatcaatca gatttgaaat
    59521 attgtagaaa aattcaccat caaatttctc cgtaaagagc ggattgtcct gacgtttaat
    59581 gattaattca tccaagatgc tcgcaaaata gataatttcc tgaatactat aaaattgtgc
    59641 agtctgctta gagtaagctt gaaaaatttt ttgagaaatt tccaaagcct gcttactagt
    59701 attaggtgaa ttttcaatgt tttgctcctg acctataaga gataacaaga ttgcaaaaaa
    59761 catcttcatc ctagcatcca tatctggaaa acctgacagt tgcttattaa caatctgact
    59821 ggccagccta gttctatctg cttctaaaat atcaaagctc ccaaaattac cggttgaaaa
    59881 atctgctact gagatacagt ttgtcagtaa aatagccaaa aatcttctct taccaactga
    59941 atcaccagaa atccgataac ctttttgtcg ttcaattttc agatcaaagt ctaaaagacg
    60001 cttatcaata tctgaaatat cctgaataat agttacatta ctgactttcg tgcactcttg
    60061 caatgcttca ttggtgacaa aaccgctctc agtcagaagg cgataggtaa tcaactcttg
    60121 tctttcttgg ggactatact caactaacac ttcaagttct gtcggcaaat catccaactc
    60181 tccagtcaaa atatagtatt tcccatgctt cgttatttcg attccatatt gctccatgct
    60241 atctgtcaaa tctgataaag ttcgataaat tgttctagat gaaacctgta agatttcagt
    60301 catatcttgc attgaaagct tccctacatg taggaaagcc ttcaataatt gttcttctcg
    60361 tttggttaat agcattcgta atttagaaac ctctagttct atttgtacat tctagcagcc
    60421 attttgtcat attctggtgt tgttactaaa ctatccacaa taagaaattg agaattcggt
    60481 gctgcttgct gcacttctgc ctgtaaagaa atagttgtta caatcattat atttttagaa
    60541 ttaaattcac ctaattctga aattttggca gtagaaactg gaatacgaat attcttgttt
    60601 ctaaagatag cccgaatcgt ttcacagccc atagttgcag ttccctgtgc tttaccataa
    60661 gcaactacta cagcatcaat agggttaagg tcaatttgct gactatctac tggtgctgaa
    60721 gttggtatat ctccttcaat ttctgctatt ggagaagctc ctgttaatga agctacaatt
    60781 tcatcataac gaggggacgc taagaaatta tcaacagaaa catgaatagc acttggactc
    60841 ttgtctttag ctcttggtgt cagttcttcc tgagtaacaa ttaatgtttt tggtgtatca
    60901 agcaaatttg agattgcctg attagatact ggaatctcta gacctgcttt tttaacctta
    60961 tctcgaagaa tactagctcc catagcagag cttcccatac cagcatcgca ggcgaaaatg
    61021 attttttcca ctgagtctgt cgaaacaact gcatcaacag aagttgatac taactgacct
    61081 ttagactgag ccttagctgc ttgggtagcc gcctgagcag cttcgagcga atcctcagtt
    61141 gacttgtctg catgaagaat aagggctgct acaaggaaag aaacaactgc tgctactaaa
    61201 acacctagaa gaacatttat atggggccaa acaccttttg gcgccgtagc cataatcgca
    61261 ataatagaac ctggtgaagc tggagattta agaccagcgt ctaagagttg aaaagtaaaa
    61321 gttccagaga tacctcccgc catagcagct aaaaatagag taggcttcat cataacataa
    61381 ggaaagtaaa tttcatgaat ccctccgaag aaatgaataa ccattgcccc ccaagaagaa
    61441 gatttagcag aacctttacc gaatacagca taagctaata gaattcccag gcctggtcca
    61501 ggattagctt ccaataggaa gagaattgac ttaccagctt gagctacctg ttctactccc
    61561 agaggagtaa aaatgccatg attgagggca ttattgagga aaaggacttt agccggttcg
    61621 atgataatat tagccatagg aaggaggcga gcattgacaa tagcctcaac accattccca
    61681 acagctccag taagagtcga tacgactgga ccgattgcat agaaagccaa aagcaataat
    61741 gcaaaaccaa cgagatcagc tgagaagtta ttaactaaca tttcaaatcc gggacgaatt
    61801 ttttcttgga acttctcatc aaatttcttg atagtccatc ctcccagtgg gcccattacc
    61861 atagctccga taaacatagg aacactagaa cctgtgattg caccaacagt agcaatagat
    61921 cctacaacgg caccacgttg gccatggatc atatatccac ctgtgtaacc aatcaggatt
    61981 ggcaataaat acgttaacat aggaccaaca acagtagcta actgttcatt tggcagataa
    62041 ccatcagcga taaagagggc agtcaatact ccacaagcaa taaatactcc aatattgggc
    62101 ataaccatat ttgaaagcga tgtccctagt ttttgaaccc tgactttcaa tgatactttt
    62161 tcttccatta gatcatcctc cttttcttaa aactagtata tacaaagtta aaaaccttta
    62221 aaactaaagt tttgtcacag attttgtgtc aaaacattac ttttgatgag gctgggcaaa
    62281 aaggctt
//
LOCUS       DAVHSI010000008        61924 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.008, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000008 DAVHSI010000000
VERSION     DAVHSI010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61924
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.008"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            42..847
                     /locus_tag="VVR21_000547"
                     /pseudo
     CDS             42..847
                     /locus_tag="VVR21_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(931..2133)
                     /gene="rpsA"
                     /locus_tag="VVR21_000548"
     CDS             complement(931..2133)
                     /gene="rpsA"
                     /locus_tag="VVR21_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU6054480.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2295..2366)
                     /locus_tag="VVR21_000549"
     tRNA            complement(2295..2366)
                     /locus_tag="VVR21_000549"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2332..2334),aa:Gln,seq:ttg)
     gene            complement(2376..2456)
                     /locus_tag="VVR21_000550"
     tRNA            complement(2376..2456)
                     /locus_tag="VVR21_000550"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2420..2422),aa:Tyr,seq:gta)
     gene            complement(2506..2736)
                     /locus_tag="VVR21_000551"
     CDS             complement(2506..2736)
                     /locus_tag="VVR21_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU6054481.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2904..3548)
                     /gene="pcp"
                     /locus_tag="VVR21_000552"
     CDS             complement(2904..3548)
                     /gene="pcp"
                     /locus_tag="VVR21_000552"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU6054482.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3563..4486)
                     /locus_tag="VVR21_000553"
     CDS             complement(3563..4486)
                     /locus_tag="VVR21_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU6054483.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4483..5172)
                     /locus_tag="VVR21_000554"
     CDS             complement(4483..5172)
                     /locus_tag="VVR21_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU6054484.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5237..5941)
                     /locus_tag="VVR21_000555"
     CDS             complement(5237..5941)
                     /locus_tag="VVR21_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6054485.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(5997..7019)
                     /locus_tag="VVR21_000556"
     CDS             complement(5997..7019)
                     /locus_tag="VVR21_000556"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU6054486.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7151..9622)
                     /gene="parC"
                     /locus_tag="VVR21_000557"
     CDS             complement(7151..9622)
                     /gene="parC"
                     /locus_tag="VVR21_000557"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU6054487.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10042..11985)
                     /gene="parE"
                     /locus_tag="VVR21_000558"
     CDS             complement(10042..11985)
                     /gene="parE"
                     /locus_tag="VVR21_000558"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU6054488.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12121..12762
                     /gene="plsY"
                     /locus_tag="VVR21_000559"
     CDS             12121..12762
                     /gene="plsY"
                     /locus_tag="VVR21_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU6054489.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12805..14076)
                     /locus_tag="VVR21_000560"
                     /pseudo
     CDS             complement(12805..14076)
                     /locus_tag="VVR21_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(14161..15117)
                     /locus_tag="VVR21_000561"
     CDS             complement(14161..15117)
                     /locus_tag="VVR21_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054490.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            complement(15120..16178)
                     /locus_tag="VVR21_000562"
     CDS             complement(15120..16178)
                     /locus_tag="VVR21_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054491.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            complement(16171..17706)
                     /locus_tag="VVR21_000563"
     CDS             complement(16171..17706)
                     /locus_tag="VVR21_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054492.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SIGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            complement(17850..18902)
                     /locus_tag="VVR21_000564"
     CDS             complement(17850..18902)
                     /locus_tag="VVR21_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU6054493.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            complement(18993..19382)
                     /locus_tag="VVR21_000565"
     CDS             complement(18993..19382)
                     /locus_tag="VVR21_000565"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6054494.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            complement(19369..20031)
                     /gene="deoC"
                     /locus_tag="VVR21_000566"
     CDS             complement(19369..20031)
                     /gene="deoC"
                     /locus_tag="VVR21_000566"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU6054495.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            complement(20049..21326)
                     /locus_tag="VVR21_000567"
     CDS             complement(20049..21326)
                     /locus_tag="VVR21_000567"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU6054496.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            complement(21323..21904)
                     /locus_tag="VVR21_000568"
     CDS             complement(21323..21904)
                     /locus_tag="VVR21_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6054497.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGNLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            complement(22120..22487)
                     /locus_tag="VVR21_000569"
                     /pseudo
     CDS             complement(22120..22487)
                     /locus_tag="VVR21_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22677..23597
                     /locus_tag="VVR21_000570"
     CDS             22677..23597
                     /locus_tag="VVR21_000570"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU6054498.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYNMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            23665..23901
                     /locus_tag="VVR21_000571"
     CDS             23665..23901
                     /locus_tag="VVR21_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU6054499.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            23954..24478
                     /locus_tag="VVR21_000572"
     CDS             23954..24478
                     /locus_tag="VVR21_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU6054500.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKATILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(24501..25211)
                     /gene="deoD"
                     /locus_tag="VVR21_000573"
     CDS             complement(24501..25211)
                     /gene="deoD"
                     /locus_tag="VVR21_000573"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6054501.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(25869..26381)
                     /locus_tag="VVR21_000574"
     CDS             complement(25869..26381)
                     /locus_tag="VVR21_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU6054502.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(26406..27386)
                     /locus_tag="VVR21_000575"
                     /pseudo
     CDS             complement(26406..27386)
                     /locus_tag="VVR21_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(27862..28671)
                     /locus_tag="VVR21_000576"
     CDS             complement(27862..28671)
                     /locus_tag="VVR21_000576"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU6054503.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSDLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(28687..29215)
                     /locus_tag="VVR21_000577"
                     /pseudo
     CDS             complement(28687..29215)
                     /locus_tag="VVR21_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(29217..30428)
                     /locus_tag="VVR21_000578"
     CDS             complement(29217..30428)
                     /locus_tag="VVR21_000578"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU6054504.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(30442..31125)
                     /gene="rpiA"
                     /locus_tag="VVR21_000579"
     CDS             complement(30442..31125)
                     /gene="rpiA"
                     /locus_tag="VVR21_000579"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU6054505.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(31407..32279)
                     /locus_tag="VVR21_000580"
     CDS             complement(31407..32279)
                     /locus_tag="VVR21_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU6054506.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLPSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            complement(32421..33278)
                     /locus_tag="VVR21_000581"
     CDS             complement(32421..33278)
                     /locus_tag="VVR21_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU6054507.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETTLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(33432..34166)
                     /locus_tag="VVR21_000582"
     CDS             complement(33432..34166)
                     /locus_tag="VVR21_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6054508.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRSQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(34166..34849)
                     /locus_tag="VVR21_000583"
     CDS             complement(34166..34849)
                     /locus_tag="VVR21_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6054509.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            35040..35270
                     /locus_tag="VVR21_000584"
     CDS             35040..35270
                     /locus_tag="VVR21_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU6054510.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            35499..37757
                     /locus_tag="VVR21_000585"
     CDS             35499..37757
                     /locus_tag="VVR21_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6054511.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDCIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
     gene            complement(37964..38914)
                     /locus_tag="VVR21_000586"
                     /pseudo
     CDS             complement(37964..38914)
                     /locus_tag="VVR21_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            38991..39446
                     /locus_tag="VVR21_000587"
     CDS             38991..39446
                     /locus_tag="VVR21_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6054512.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVHAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYSNPAYLY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWQKQHKIG"
     gene            39611..39910
                     /locus_tag="VVR21_000588"
     CDS             39611..39910
                     /locus_tag="VVR21_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU6054513.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            40171..40494
                     /gene="tnpB"
                     /locus_tag="VVR21_000589"
                     /pseudo
     CDS             40171..40494
                     /gene="tnpB"
                     /locus_tag="VVR21_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(41223..42950)
                     /gene="ezrA"
                     /locus_tag="VVR21_000590"
     CDS             complement(41223..42950)
                     /gene="ezrA"
                     /locus_tag="VVR21_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU6054514.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(43032..44978)
                     /gene="gyrB"
                     /locus_tag="VVR21_000591"
     CDS             complement(43032..44978)
                     /gene="gyrB"
                     /locus_tag="VVR21_000591"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU6054515.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(44993..45556)
                     /locus_tag="VVR21_000592"
     CDS             complement(44993..45556)
                     /locus_tag="VVR21_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU6054516.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(45641..46195)
                     /locus_tag="VVR21_000593"
     CDS             complement(45641..46195)
                     /locus_tag="VVR21_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU6054517.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(46206..47429)
                     /locus_tag="VVR21_000594"
     CDS             complement(46206..47429)
                     /locus_tag="VVR21_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6054518.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(47466..49916)
                     /locus_tag="VVR21_000595"
     CDS             complement(47466..49916)
                     /locus_tag="VVR21_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU6054519.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVFLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYFVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(50116..51045)
                     /locus_tag="VVR21_000596"
     CDS             complement(50116..51045)
                     /locus_tag="VVR21_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU6054520.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            51185..51472
                     /locus_tag="VVR21_000597"
     CDS             51185..51472
                     /locus_tag="VVR21_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU6054521.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAVAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(51506..52840)
                     /gene="ciaH"
                     /locus_tag="VVR21_000598"
     CDS             complement(51506..52840)
                     /gene="ciaH"
                     /locus_tag="VVR21_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU6054522.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(52830..53504)
                     /gene="ciaR"
                     /locus_tag="VVR21_000599"
     CDS             complement(52830..53504)
                     /gene="ciaR"
                     /locus_tag="VVR21_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU6054523.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(53613..56159)
                     /locus_tag="VVR21_000600"
     CDS             complement(53613..56159)
                     /locus_tag="VVR21_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU6054524.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(56282..56722)
                     /locus_tag="VVR21_000601"
     CDS             complement(56282..56722)
                     /locus_tag="VVR21_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU6054525.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(56697..57344)
                     /locus_tag="VVR21_000602"
     CDS             complement(56697..57344)
                     /locus_tag="VVR21_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU6054526.1"
                     /translation="MKNQLALSGEKILEKIYPLFGYRGTRRLLACLDEFQAEAHVITE
                     VYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIELPSAYFDLSSILETGI
                     SKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKARKNKINFAVAGYLNTS
                     FIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKKLQRSTHDTARNVE"
     gene            complement(57386..58114)
                     /locus_tag="VVR21_000603"
     CDS             complement(57386..58114)
                     /locus_tag="VVR21_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054527.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(58122..58601)
                     /locus_tag="VVR21_000604"
     CDS             complement(58122..58601)
                     /locus_tag="VVR21_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6054528.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(58612..59310)
                     /locus_tag="VVR21_000605"
     CDS             complement(58612..59310)
                     /locus_tag="VVR21_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU6054529.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     RFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(59303..59569)
                     /locus_tag="VVR21_000606"
     CDS             complement(59303..59569)
                     /locus_tag="VVR21_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU6054530.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(59635..60561)
                     /locus_tag="VVR21_000607"
     CDS             complement(59635..60561)
                     /locus_tag="VVR21_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU6054531.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(60636..61451)
                     /locus_tag="VVR21_000608"
     CDS             complement(60636..61451)
                     /locus_tag="VVR21_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054532.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSIFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(61455..61775)
                     /locus_tag="VVR21_000609"
     CDS             complement(61455..61775)
                     /locus_tag="VVR21_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6054533.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT        18544 a        13715 c        10969 g        18696 t
ORIGIN      
        1 gttgaaacag tccggggagt gactgtttca atcgggagat ggagatgagc tttattgcgc
       61 aagattttga aaagctcgat atcatcactg ttcttgaggg tagaacacaa gctgtcatcc
      121 gagatcactt tcttaaatat gatagagccg tccgatgtcg cgtcaaaatc attactatgg
      181 atatgtttag tccttactat gacttggcta aacagcttcg ctttcaaatt tctaggctca
      241 ggctgaaaca gtctcccagg ctgtttcact cccgaatgct aaaatcgttc ttgatcgctt
      301 tcacattgta caacatctta gccgtgctat gagtcgtgtg catgtccaaa tcatgaatca
      361 gtttcatcga aaatcccatg aatacaaggc tatcaagcgc tactggaaac tcattcaaca
      421 ggatagccgt aaactgagtg ataagcgatt ttatcgtcct acttttcgta tgcacttaac
      481 caataaagag attttagaca agcttttgag ctattcacaa aacttgaaac accactatca
      541 gctcttgctt tttcacttcc agaataagga accagagaaa cttttcggac ttattgagga
      601 caatctgaag caagttcatc ctatttttca gactgtcttt aaaaccttct tcaaagataa
      661 ggaaaagatt atcaacgccc ttcaactaca ctattctaat gccaaactgg aagcgaccaa
      721 taatctcatc aaacttatca agcgcaatgc ctttggtttt cgaaactttg aaaatttcaa
      781 aaaacggatt gttatcactt tgaacatcaa aaaagaaagg acgaaatttg tcctttctcg
      841 agcttagctt ttttcaaccc actacagttg acaaagagcc gaaaaatccc ttgtttagta
      901 aacaaaggat tttgtgaatt ttcaatttga ttaaagttcg atatcaccaa acaaatcagc
      961 cattgaaaat cctgtttgtg tttctggaag ttcgaaatca cgcttttctt gacgtcttgg
     1021 acgacgtgga cgagcagcac gtttttcttc tttttgtcct tcttcttggg ctggacgttc
     1081 ttcaagagct ttaatagaaa gtgatacgcg ttctgcatct gcgttaactt caagaacttt
     1141 aacttgaact tcttgaccaa ctttaagagc ttcttttgga ttttcaatcc gtttgtgtga
     1201 aatttgtgat acgtgaacaa gtccatcgat acctggcaat acttcaacaa atgcaccgaa
     1261 gtcagtcaaa cgtttaactg ttccttctac tacatcacct ttagccaatt tttgctcaac
     1321 gccatcccat ggtcctggta ctgttgcttt aagtgaaagt gatacacgtc cttcttcttc
     1381 gttaagatca aggattttca cttcaatttc ttcaccaaca gttacaactg attttggtga
     1441 tacgttacgt tcatgtgaca attcagtcaa gtgaaccaat ccgtcaacac caccaaggtc
     1501 gatgaaagcg ccgaagcttg tgatacgagc aactttacca gttacaacat caccaacagc
     1561 caatttaccg aatacttcag cgcgagctgc tgcagtagct gcttcaacaa cttcacgacg
     1621 tgaaaggatg aagcggtttt ctttagcgtt aacttctttg attttagtat caaattcttg
     1681 acctacaaaa cgctcagcgt tacgtacgaa acgagtatcc aacattgaag ctgggataaa
     1741 tccacgaaca ccttcaaatt ctactgaaag tccaccttta acggcacgcg ttcctttaac
     1801 agtaacaact tcttcttcgc gaccaacaag tttgtcccat gctttgcgag cttcaaggcg
     1861 ttttttagat acaaggtatg taactgtatc agtatcttta ccaactactt gacgaagtac
     1921 aagaacatcc aatacttctc ctactttaac aaagtcattg atatctgcat cacgatcgtt
     1981 tgtcaattcg cgaagagtca agacaccttc aacaccagtt ccagagattg caacgttagc
     2041 ttgagtcgca tcaactgtca atacttcagc actaacaaca tcaccagtct caacttgact
     2101 aacgctattt agcaaatctt caaattcgtt catctaaaaa atcctccaac aatcaagttt
     2161 ttcttaaact tgacatactt ataatttttt tcctaagcac ccgcaaggac atgttcatat
     2221 cattcacgtc tttcaattat aaaaataaaa taccctaaga tattttgctt tttatcttga
     2281 ttattaccta agaactgggg tagctggatt cgaaccaacg catgagggag tcaaagtccc
     2341 ttgccttacc gcttggctat accccattaa tgaaatggag agagagggat tcgaaccccc
     2401 gaacccgaag gagcggattt acagtccgcc gcgtttagcc tcttcgctat ctctcctaca
     2461 atcaacatgg actattatat catgaaaatt tcaaaaaaac aagacttatt ttgctaaatt
     2521 ataattttca atcaaaattt ccacagcttt ttccaatttt ttataaaaac tatcgacatt
     2581 cccattcttt ataatggcaa attgtccgtc taattcggca atttctccga taactttttt
     2641 accgatagtc aatgtataac cttcaaaact gtctttacca acattaactt tggcatccgc
     2701 tacttgaatt tcgatttttt tatctttctt gctcatttca tacctctctt cactttttct
     2761 attttacaag aaaatcctaa aactagcaag aaaaaactct atatcaggct tctctgatat
     2821 agagttttat gtaaacaacc tcaatcgatt tagcatagct aatagttagt aaacaagcat
     2881 aattgactat cctttttagg ttatcagtga gtctcaccgc ctactaactg caaatcctta
     2941 tctttgtagt ctacaatagc ttcaatagct acctctatgc ctcttacaat atcacataga
     3001 ctcattcctg cagtattcgg cttatttact acttgttcca tcatatatgg aatatgcatg
     3061 aaacctgctc tcatattagg gaatttttta tccactaaat aaagagcttg gtacatcaaa
     3121 tgattgcaaa caaaggttcc tgcactattg gatacaactg ccggaagtcc ctgttttttg
     3181 atagcttgta ccatcgcttt gataggtaaa ctactaaaat aggccgatgc tccatcaata
     3241 cgaatcggtg tatcaattgg ttgattgcct tcgttatcag gtatgcgagc atcatcttga
     3301 ttaatagcca ctcgttcagg tgttaagccg gtcctgccgc ctgcttgtcc aatacaaagt
     3361 acagcatctg gttgatatcg taatatttct gcctctaaaa cttctgacga cttataaaaa
     3421 accgttggaa tttctaccca gcgaacttca gccccattaa tctcagatgg taataatttt
     3481 acagcctcca aagctggatt aatcttttca cctccaaaag gattaaaacc tgtaaccaat
     3541 attttcattt tattttcctt tactaaaatg cgagaaagta cattaagaat atgtgaataa
     3601 caatcattac tagagcaaca cctgcttgag cctttataac gccattctga tctttcatat
     3661 ccatcaatgc tgctggtaga gcgttaaaat tagcagccat tggggtcaat aaggtcccac
     3721 aataacctgc tgtcatggca agagcaccag ccacaattgg attagctccc agagcaaata
     3781 caaagggaac tccaacacct gctgtaataa cggtgaatgc tgcaaaagca tttcccataa
     3841 tcattgtgaa tagaaccatt ccaagaacat aggccaaaac tcctataaag cgactatctg
     3901 aaggaacaat accgctaatc agatgagaga taacatcacc aacacctgct acagtaaaaa
     3961 tagcccccaa agcccctaat aattgaggaa caataccact tgttgaaact tgctgagtca
     4021 ttcgattatt ttctgataac agactcttag ggtgactatt ggtaatcaca agaacagaaa
     4081 ttgtagcaaa caaggcggca aggctaatcg aaatcttgct aaattctgga atcatttgcg
     4141 ctaagaccaa cgcaagtatt gccatcagca taactggaat aaaaatttta tttttcaacc
     4201 tgttagattc aatattggct ttcatttcat ctaaggatgg caaggttccg atacggactt
     4261 gcttaaacaa tgttaacagc gataatagga ttacaataat accaatactc atatttggca
     4321 tataggaacc acctataaac gtaatagaca atagagtcca aaatgcagat gtcccaagtc
     4381 gaactgggtt tgttttatct ttataactac aataggctgt atggagaaat tgacaaccaa
     4441 tcacaatata ggtcaactct aatagttgct ttgccaactc tgtcattttt gttctcctcc
     4501 cctagtcttt tttgatatca attttttatc aaataaataa ttgtaaatcc ccactacaat
     4561 aagtgttata acagcaacaa taatagatgt agaagcaatc cctgcataat tgctttcata
     4621 gcctaactga tctaatgttc cccctatcaa gaggactccc ccagcaccta caaacgtatt
     4681 ttgagcaaag aaatttccaa aattttcatt cgcagccgca cgcgctttta ttgtctcatc
     4741 ttcaacctct gttaactttc tacctaattg agactctgca gctgcttctc ccataggttg
     4801 aaccaaaggt ctgacaaact gagggtgtcc tcctagacga attgaaaaga aaccagctaa
     4861 ctctcgaata aaaaaataaa ctgtatagaa gtttccaact gtcagacctt taatctttcg
     4921 aatcaaatcg attgatcgtt gcttgagtcc aaaggtttct gacagcccca caagaggcaa
     4981 ggtaaccata aaaatcgtga gcactcgctg attgctaaat tcttttccca aaatctccaa
     5041 aaattcaacg agagaaacac ctgaaactaa agctgtaacc aaaccagcta agactactgt
     5101 tgcaattgta tcaaatttta aaataaaacc cacaacaatg attgctattc ctattaatct
     5161 aatccactcc atatcaaact cctttatatt caaaatgaca gtattttaaa aattttatca
     5221 agatcaatac cattccttat ttaatgtatt tttctagttc tttttggtat ttgctattgg
     5281 attccaattt ttctttttgc cattttttaa aaacctcgtt atattctttt gttgtaacaa
     5341 tatctttttg caatttcatt cctttaaaga tatatggttc ccccttaata ccaacttgtg
     5401 agtatggttt tgagaatggt actacgttac ttacaactgg agaaccacca gatgaagctg
     5461 ttggcatcaa taatgaacta tctgtcgacc aagcttgagc tttggcatat ttttcatatc
     5521 tcttctctag gtcagtggtc tcagaaacag catcttctaa caatttctta tatttatcca
     5581 aaccaggttt agctacaaca tccttatctt ttcctttcgt aataccaagg tgtttcatgg
     5641 cagaaccaga ttttggatcc ataatattca agtaagacgc tggatcttga tagcttggag
     5701 cccatcctgt actattcaaa tcatagtctt tttgagaagg agcaacattg ccgtatttat
     5761 cattttccat caaaccatca ataacatttc caataacgtc tgtcctcgat gttcgagtcg
     5821 ctatactgta gcccaatgat gctggatcta ctgcatagac ataagaaaat gttgtcggtg
     5881 catctgcttc tttatcagtt tttccacaag ccactaaaat agctgacgtg ctcaggacca
     5941 ctcctgctgt taagagccac tttttctatt tcataaaaaa tctcctttgg tttattttaa
     6001 tctactttta caatccaacc ttctggcgct tcaatatcgc caaactgaat acccgtcaat
     6061 tcattatata atttacgcgt cacaggacct acttctgttt cactatagaa tacatggaaa
     6121 tcatcaccat gttgaatacc tccaattgga gaaataaccg ctgctgtacc acaggcacct
     6181 gcctctacaa aacggtcaag attatcaatt ggaacatcac cctcaatagg agttaatccc
     6241 aagcgatgtt ctgccaaata aagcaaggaa tacttggtaa tagatggcaa gatagatgga
     6301 ctcaatggtg ttacaaattc attatcagct gtaattccaa agaagttagc tgatccgact
     6361 tcttcaatct ttgtatgagt tgatgggtcc agatagataa catctgagaa atgacgtgac
     6421 ttggccattt ttcctggtaa gagacttgca gcatagtttc caccaacctt agccgcacct
     6481 gtaccatttg gtgctgcacg gtcgtactca tcctgaatca agaagttggt tgggaccaaa
     6541 ccacctttaa agtaatttcc aactggcata gcaaagatgg tgaaaatgta ctcttctgcc
     6601 ggttttaccc cgataatatc tccgacacca atcaaaagag ggcgaagata taaggttcca
     6661 cctgttccgt atggtggtac gtattcttca ttcgcacgga caactgcttt acaagcttct
     6721 acaaacatgt ctgtcggaac ttgtggcatc aagagacggt cacatgtacg ttgcagacgt
     6781 ttagcatttt catcaggacg gaacagttga acactgccat ccttagtacg ataagctttc
     6841 aaaccttcaa atgcttgttg tccatagtga agacttggag aagactctga aatatgcaaa
     6901 gttgcatcct ctgtaagctc tccttgatcc cattgtccat ttttgaaatg agcaagatag
     6961 cgataaggta atttcatata ggaaaaaccg aggttttccc aatcaatcgt tactgtcata
     7021 ttccactcct tattctaaaa acctatttct tatattctac actatttttc taaaatagca
     7081 agtatatttt gtaattttca gaaaatttct ccaataaaaa ccagctctta gaactgattc
     7141 ttcatttcac ttatttatct tcagtaacta cttcctgaag ataagcgtca aaaacttctt
     7201 catctgaaat cgtgtcagaa atgaagcttc cattgctagt gcgttctgac aagttcaagt
     7261 cttgcaatcg gctttcatag attgttcctt tattggattg gacaagcaga gtttggtcgt
     7321 tcacatccac ttccgtactg aagaaatcgc caacaaatcc ttgctctgca actgctcctg
     7381 ccaagaagac acgatgcggt ttgtttttca actcacgcaa gacttgtaat cctcgtttgg
     7441 cacggctggt tgctagaatt tcctcaatgg aaacacgttt caagcttcca cgctgggtca
     7501 agaggtagaa ggacgaagta ttacagataa agccagattg gaggacatca tcttctttca
     7561 aattcatagc cttgacacct gctgccttag caccgacaac cggaacctct tcgatattga
     7621 aacgcagggc ataaccattt tgactaacca agacaacatc atctagttta atcggagcca
     7681 ctgctacaat ctgatctgta tcgtctttga gcttagcata cttgacagac ttagatctat
     7741 aggtccgcca tggagtgaat tcttttcgct ctacccgttt gatttgacca aggcgagtca
     7801 ctgcaaagta ggttgtcgca tcgtcaaact gatccagtac ttccacataa aggatttctt
     7861 cattcgtttc aaagtttgtg atggtttggc tcagatgctc tccgatgtcc ttccaacgaa
     7921 tatctgccaa ctcatggatt ggtctgtaga tgacatttcc aagacttgtg aacatcaaga
     7981 ggtgctgggt tgtcttggca gattgaacaa aaatcaaacg gtcatcatca cgcttgccaa
     8041 tttcttccaa ggtggaagcc gcaaaggaac gtggactggt acgcttgatg taacctgcct
     8101 tggtcacgct gacgtaggta tcttcctcag cgataagact agctgtatca atctcaattg
     8161 ctttcgcagt atcttctaaa gaactcaaac gaggagttgc aaatttcttc ttgacctcac
     8221 gaagttcttt cttcatgaga ttgtacatag tcctttcatc accgataata gccgccagca
     8281 tagcaatctt ctcacgaagc tctgcttctt cttcctgcaa gacaaccaca tcggtattgg
     8341 tcaaacggta cagttgcaaa gttacgatag cctcagcctg ttcttccgta aaatcatagc
     8401 taactttgag gttttccttg gcgtccgcct tattctcaga agcacggata agagcaatga
     8461 cttcatccaa aatcgaaatc acacgaatca aaccttcgac gatatggaga cgtttctcag
     8521 ccttttcttt gtcaaagcgt gaacgcgcca aaatcacttc tcgacggtga gcgatatagc
     8581 tagacaggat tggaacaatc ccaacctgac gaggtgtgaa attgtcaatc gccaccatat
     8641 taaagttgta gttgatttgt aggtcggtgt acttaaataa gtagttgaga acaagctcag
     8701 tattagcgtc tttcttaagt tcgatagcga tacgaagacc atcacggtca gactcatcac
     8761 gaacctcagc aatcccagct accttgttat taacacgaac atcatcgatt ttcttgacta
     8821 gattggcctt attgatttca taaggaatct cagtaataac gatttgttcc ttaccacctt
     8881 ttagcttttc aatttcagtc ttggaacgaa caaccacgcg ccctttccca gtctcataag
     8941 ctttcttgat ttcatcacga ccctgaataa tagcccctgt agggaagtct ggtccaggca
     9001 agaattccat gagtttatca atctttgcag ttgggtggtc aatcatgtaa actgcagcat
     9061 ctatgacctc agctaaatta tggggaggaa tgtctgtggc ataaccagcc gaaatcccag
     9121 tcgaaccatt gaccaagagg tttggaaagg ctgctggcaa gaccgttggt tctttctccg
     9181 tatcgtcaaa gttccatgca aaaggaactg tctttttctc gatatcctga agaaggtagc
     9241 ctgcaatttc agacaaacgt gcctcagtat aacgcatagc cgcaggagga tctccgtcca
     9301 tagaaccgtt attaccgtgc atttcaacta gaatctcacg atttttccag ttctgtgaca
     9361 tacgaaccat ggcatcatag atagaagaat ccccgtgtgg gtggaaattc cccatgatgt
     9421 tcccgactga cttggccgac ttacggtagc tcttgtcaaa agtattgcta tccttattca
     9481 tagaataaag aatacggcgc tgaaccggct tcaacccatc acgaatatct ggcaaagccc
     9541 ggtcttgaat aatgtacttg gagtagcgac caaagcgctc tcccatgatg tcctccaggg
     9601 acatattttg aatgttagac ataagataca aagcccataa aataccaagt gaaaatagaa
     9661 aattcttgaa gtaagcaaac tcacaagaga atttatcttt ttcacacagt atctagggcg
     9721 tgttcaactc ctttcaaaga atgtagagta ggtttttatg cagtaaaaga tattttacgg
     9781 gaattcctcc cgtgttcagt tacgataagt aaccaaacta tcctgtttgt atttttcaat
     9841 atgaaaatct ggttttccaa aattagtctt agtttgtgtc ttagtcgctc ccttaaacgc
     9901 ctctttgaga taagcactca tagcagattc ttcattaata atcctgcaat tttttcaaac
     9961 caagattttc aaactgcttt ttcacatagt cattcacatc cgactctaat ttccagttta
    10021 ctaacatatt attttctttc attaaaacac tgtcgcttct tctagcgtaa acttgacatt
    10081 atcttcaatc catttacggc gtggttctac cttatctccc atgagaacat tgacgcggcg
    10141 ttcggcgcgc gctaaatctt caattgtgac acggatgagg gtacgtgttt ctgggttcat
    10201 ggttgtttcc cagagctggt ccgcattcat ctcaccaagt cctttgtatc gttggagggt
    10261 agcgccttta ccgaactgtt tacggagttc ttctagttct ccgtccgtcc aagcgtaggc
    10321 cacttcttct ttcttgcctt tacctttgga catcttgtaa agaggtggga gggcaatata
    10381 gacatgacct gcctcgacta gcggacgcat gtaacggtag aaaaatgtca agagcaaggt
    10441 ctggatatgg gcaccgtcgg tatccgcatc ggtcatgata atgatcttat catagttggc
    10501 atcttcaata gagaagtctg ctccaacacc cgcaccaatg gtataaatca tggtattgat
    10561 ctcttcattt ttgaggatat ccgccatctt ggccttggct gtattgacaa ccttaccacg
    10621 aagaggtaga atagcctgga acttgcggtc acgaccttgt ttggcagaac caccggcaga
    10681 gtccccctca actagataga gttcattctt agcaggattc ttagattggg ctggggtcaa
    10741 tttcccagac aacaagccct tatctttctt gtttttcttc ccatttcggc tctcatcacg
    10801 cgccttacgt gctgcttcac gagcatcacg agccttgata gccttgcgga tgaggttaga
    10861 agctaattcc ccattttcca taaggaaaaa ggtcaactta tcagccacta ttccatccac
    10921 aactgggcga gctagggggc ttcctagttt atccttggtc tgtccttcaa actgcaagtg
    10981 ttcttcagga actaagatag aaagaacggc cgctagtccc tcacgatagt ctgaaccttc
    11041 aaggttttta tctttttcct tgagaagacc tgttttacgt gcatagtcat tcatgacctt
    11101 ggtaatggca gacttgagtc ctgtctcgtg cgttccaccg tccttggtgc gaacgttatt
    11161 gacaaaggat agaatgttat ctgagaatcc gtcattgtac tggagggcta cttccacttg
    11221 aaaaccattg tcttcccctt caaagtaaag aactggcgtc aagatttcct tatcttcgtt
    11281 gagataagaa acaaaatctt gtactccatt ctcatagtgg aactcaatcg cttcatctgt
    11341 tcgcttgtcc gttaaagaca aggtcacatt tttcaagaga aaggctgatt cattaaggcg
    11401 ctctgaaatg gtattgtact tgaaatctgt cgtagaaaag atagtcgcgt caggcataaa
    11461 agtaactttg gtgcctgttt tagacttggg tgctgtaccg attttcttca aagtcgtgac
    11521 aggttttcca ccattttcaa aacgttgctt gtaaactgcg ccatcacggg taatttcaac
    11581 ttctaaccag ctagaaaggg cgttaacaac ggaagaaccc actccgtgaa gtccacctga
    11641 tgtcttatag ccaccttgac cgaatttccc tccggcatga agaatggtaa agataacctc
    11701 aacagttgga attcccatag cgtgcatacc tgtcggcatc ccacgtccat ggtcttgaac
    11761 cgttagacta ccgtctttat tgatagttac atcaatacga tcaccaaacc cagacaaggc
    11821 ttcatcgact gcattatcaa cgatttccca aactaggtga tgaagaccag cgccatcggt
    11881 cgatccaata tacatccctg gacgttttcg gaccgcatcc aacccttcta gcacctgaat
    11941 agcatcatca ttataattgt taatattgat ttcctttttt gacacaagga acctcctatt
    12001 cgttcatctt tactattcta caggttttcc aaggattttg caaaattttt ctttctccga
    12061 tgtgacaatt ttagcagaga ttctctgctt ttctttccca attcatgata taataggagt
    12121 atgattacaa tagttttatt aatcctagcc tatctgctgg gttcgattcc atctggtctc
    12181 tggattggac aagtattctt tcaaatcaat ctacgcgagc atggttctgg taacactgga
    12241 acgaccaaca ccttccgcat tttaggtaag aaagctggta tggcaacctt tgtgattgac
    12301 tttttcaaag gaaccctagc aacgctgctt ccgattattt ttcatctaca aggcgtttct
    12361 cctctcatct ttggactttt ggctgttatc ggccatacct tccctatctt tgcaggattt
    12421 aaaggtggta aggctgtcgc aaccagtgct ggagtgattt tcggatttgc gcctatcttc
    12481 tgtctctacc ttgcgattat cttctttgga gctctctatc ttggcagtat gatttcactg
    12541 tctagtgtca cagcatcgat cgcggctgtt atcggggttc tgctctttcc actttttggt
    12601 tttatcctga gtaactatga ctctctcttc atcgctatta tcttagcact tgctagtttg
    12661 attatcattc gtcataagga caatatagct cgtatcaaaa ataaaactga aaatttggtc
    12721 ccttggggat tgaacctaac ccatcaagat cctaaaaaat aaaacgccag ttctgtactg
    12781 cccccaaaca gttagacaaa taatttatcc aaaggattta gttctgtatt gcacaaggct
    12841 aagtcctttt agttttacct taattcgttt attgttgtag taatcaatat agtctacaat
    12901 agcttgttcc aattgattaa gtgatttaaa tgttttctca tagccataaa acatttccga
    12961 tttcagaatc ccaaagaagg actccatcat accattgtct tggctgtttc ccttgcgtga
    13021 catagatgct tgaattccct tactctctag gaaccgatga taagaatcgt gttgatattg
    13081 ccagccttgg tcactatgga gaatcgtatt ctcgtagtgc ttctctttga atgcctgttc
    13141 caacattgtt tgtacttgtt ctaaattagg cgaacaagaa agattaaaag caataatttc
    13201 gctgttaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg ctggaatggc
    13261 aaattctgtc acatctgtgt agcacttttc cattgtttta gagccttcaa attggccttg
    13321 aatgagattc tctgccttct tgctaacgtc tcctttatga gaagaatatt ttcgtttctg
    13381 tcgcatttta gcttgtaaat tgagtacttt catcaagcct tgaactcttt tatgatttac
    13441 cagataagca cgatttctta gttctaaatg aacccggcga taagcataat ttcctttgtg
    13501 ttcgataaaa atggattgaa tttcagcttt aagctcttgg tccttatctg ttttgtctag
    13561 ctgtttcaag tgatagtagt aggtccaacg agctagttta atggatttta gaagaagatc
    13621 taacgaaaac tcagtcatta attcttgaac aatttctgtc tttcttcttt ctctttttcc
    13681 tccttcaatc ggagttctct taactttttt aggatggcat tctccgctct caggtactct
    13741 cccttttgtt ttctcaacaa tagtataccc gtttttcctg tattgtgcta gccagttaag
    13801 aagtatcgta cgacttggga ggccgtattc aagagaaact ctatctttag tccagccttc
    13861 atgtcagact ttattactca tttcttgttt taaatcagga gaatagtaac gattttttcc
    13921 ttttttgacg aactctattc cgtaacgatc aatcaattta atcatgtacc taagattaga
    13981 attatttatc ccaaatttat ttgaaagttt ctctaagcta tatccttgtt ttctaagttc
    14041 atagatctga actttatcat cataagttag tttcataata aaaacacccc aaaagttaga
    14101 ttttttctgt ctaacttttg gggggtagtt cagtcattgg actgacgttt ttttgtatgc
    14161 ttattttgat ttgatgtagt tgataccatc tgcttttggt gcgactgctt ttccaaagaa
    14221 ggctgctaag acaagaattg tcaaaacata aggtgcaatt tgaagataaa ccgctggcac
    14281 tccttgtaga aacggcaatt gagaaccgat aacagccaaa ctttgtgaaa gtccaaagaa
    14341 gagactagaa agcatagcac cgattggatt ccatttccca aagatcatcg cagcaagggc
    14401 gataaatcca ggtccaacaa tagttgtcac tgagaagtta actgagattg attgcgcata
    14461 aatcgctccg ccaattccac ctagaaaacc tgaaataata atccctaaat atctcatctt
    14521 gtagacgttg attcccaagg tatccgctgc ttgaggatgt tcaccgacag agcggagacg
    14581 aagaccaaat tgagtcttaa agagaataaa ccaagcaagg aatgagaagg caatcgccag
    14641 ataaccaagt agactagttg acttgaagaa gatatcacca atcactggga tatttgccaa
    14701 gactgggaaa tcaaagcgtc caaaagtttg acttaggttg tcggtttgtc ctttgttata
    14761 aagaacttta actaagaaaa cagccaaggc aggcgccatc aagttcaata ccgtaccgct
    14821 gacaacatgg tctgcacgga aatgaaccgt cgctgctgcg tggatgatag agaaaacact
    14881 accaaccaat cctgctacaa gcaaggatag ccatggagtt gctgctccaa attgttctgc
    14941 aaattcaagg ttaaagacaa ctccagaaaa ggcacccata accataattc cttcaaggcc
    15001 aacgtttacc acaccaccac gttcagagaa aacaccaccg atacttgtaa agatgagagg
    15061 tgctgagtaa atcagcatag aagacaccaa gagggggagc aaggttataa tagacatctt
    15121 tacttacctc ctttaacttg ttttttcggt ttgacaaagc gttcgataag gtaatgaaca
    15181 ctgacaaaga agataataga cgctgttaca atgctgacaa gctcagatgg tacctgcgcc
    15241 gcattcatac caggagcccc aacttggaga acgccaaata ggaaggctgc aaagagtata
    15301 ccaattggtg agttggccgc aagcaaacta accgccattc cgttaaatcc gatagctaat
    15361 gacgaacctt gaacatagac gttctggaag gttcccaaac cttcaacagc tccaccaaga
    15421 cctgccaagg cacctgaaat aatcatagat aggataatag tccgcttggc agaaatacca
    15481 gcatattctg aagcatgtgg attaagacca actgcacgga tttcaaaacc aagagttgtt
    15541 ttcttgagca tgaaccaaat aactgcaacg gcaatgatgg caaagaaaat accaatattc
    15601 atccgtgagt taccagtcaa ctcagccaac caaggtgtct gataggttgc attagcccca
    15661 acacgaatgg tcgaatctgt actttgcatg aagtctttag ggaaagcatg gataaaggca
    15721 ttccctacat acaagacaat gtagttcatc atgatggtta caataacctc tgacgtccct
    15781 agataggccc taagaatacc tggaatcgct ccgacaatcc caccagcaat caaggcaatc
    15841 acgatggttg ctagaatcat caagggacgg ggcatatctg gatgcgacag ggcaaaccaa
    15901 ccactgagaa tccaacctgc caaagcctga ccaggaagtc cgacgttaaa gaaaccagct
    15961 cgactggcaa ccgcaaaacc aagaccaatc aagaccagag gacccatagc acggaagatt
    16021 tctccaatcc cacgcagact gccaaaggct gtatagaaca attcttcgta gccccaaata
    16081 gcatcataac cgaagatcca catgacaatg gctccgagta aaattcctag aaatacagaa
    16141 atcaagggaa ccgaaatttg ttgtaatttt ttagacatca ctcttctcct ttcccaagtt
    16201 tccaccagcc atcaagacac caagttcttg tttattggtt gtttctggtg atacaatacc
    16261 ttgaatctta ccatcgtgga taacggcaat acggtctgag acgtttaaaa tctcatccaa
    16321 ttcaaagctg acaacaagga cagccttgcc attatcacgc tcttcaatca agcgtttgtg
    16381 gatatactca atggcaccga catccaaccc acgagttggc tggctaacga taaggagatc
    16441 aggatctcga tcaatttcac gagcaataat tgctttttgt tgatttcctc ctgagagtgc
    16501 agctgcagga actaattcac tggcagcgcg aacatcaaac tcttccatca gctttttagc
    16561 ataagaagta atatttgaat aattcaaaat tccattttta ctatgtggtt ctttatagta
    16621 ggtttgaagg gcaatatttt cagatatcat catttccaaa atcaagccat cacggtgacg
    16681 gtcttctgga acgtgcccaa tacttagttc tgtaatctga cgtgggtgca agcctacaat
    16741 tgaatctcct tttagctcaa tgctaccaga ttcaacctta cgaagacctg taatggcttg
    16801 aatcagttca gactgaccat ttccatcaat ccccgcaata ccaacaatct ctccagcacg
    16861 aacatccaag gacagatttt taacagctgg aacaccacgg ttttcattga ccaccaaatc
    16921 tttgatagac aaaaccactt cttttggttt agaggcttgc ttctctgttt taaaggaaac
    16981 agaacgtcct accatcattt ccgccaaatc agcattggta gcccctgcaa tttcaacggt
    17041 ttcaattgat ttcccacgac ggataactgt aacacggtca gaaactgcgc gaatttcatc
    17101 caatttgtgg gtaatcaaga taattgattt tccttctttg acaagatttt tcataatagc
    17161 catcaactca tcaatttctg atggagtcaa aacagccgtt ggttcgtcaa agataaggat
    17221 atcagccccc ctataaagtg tttttaaaat ttctacacgt tgttgggctc caactgagat
    17281 atctgctacc ttggcagaag ggtcaacagc taagccataa cgttcagaaa gagccttgat
    17341 ttctttgcta gctccagcga tatctagcac accattttta gtcaattcac tacctaaaat
    17401 gatgttttca gccactgtga aggcttcaac caacataaag tgctggtgaa ccatcccgat
    17461 tcccaagcta gctgctttag atggggagtc gagattgaca acttgaccgt tgaccgcgat
    17521 ttcaccacta gttggttcaa gaaggcctgc taacatgttc attagcgtgg acttaccagc
    17581 cccattttct cctaaaagtg catgaatttc accttttcgt aggtgcaagt tgattttgtc
    17641 gttggcaaca aatccaccaa acaccttggt aatatcacgc atctcaatga cattttcgtg
    17701 tgccatgtgc tcttcctttc agagtcttat tttatttcaa taaaacttgc tagtttgtct
    17761 agtagcaagc tttactgaga caaaatgact ttgtctcaac tcttaaaaaa gcggcccttg
    17821 gccgcttcct aagaaatgac ttccatccat tatttttcag gaacttttac gcttccatca
    17881 aggattttag cttttgcatc ttcgacagct tttttacctt cttctgaaag gtttgttact
    17941 gccaagtcaa cccctttatc cttcaatgag taaacgatca cttgaccgcc agggaattct
    18001 cctttttctg ccttgttaga aatatctttt acagttgtac caacttgttt caaagtagat
    18061 acaagaacaa agtttgattc tttgccatct ttagaagtgt atttaccttc tgcttcttgg
    18121 tcacggtcaa caccgataac ccaaactttt tcattttcag gacggctttc gttgagagat
    18181 tttgcctctg caaagacacc tgcacctgta ccaccagcta cttggtaaac aatatctgca
    18241 ccggctgcgt attgtgcggc tgcaattgtt ttacctttag ccgcatcacc aaatgaacca
    18301 gcgtagtcaa cttggacttt gatagatggg tctactgacg caacaccagc cttgaatcct
    18361 gcttcaaaac gagagataac ttcagattcg ataccaccta caaaaccaac ttgttttgtc
    18421 ttagttgttt ttgctgcagc cacacctgca aggtaacctg actcattatc agcgaaagtt
    18481 acgctcgcaa cattcttttg gtctttaatc acatcatcaa tcaagacata gttcaagtca
    18541 gtgtgttctt tagctgcttc ttcaactgca ttgtgaaggg caaaaccaac accaaagatt
    18601 aggttgtaac ttccagccgc ttgttgcaag ttgttagcgt agtcagcttc acttgttgat
    18661 tggaagtaag tgaaaccgtt atcttttgaa agattgtgtt ctttacccca agcctgcaaa
    18721 ccttcccaag ctgattggtt gaatgatttg tcatcaacac caccagtatc agtgacgatt
    18781 gctgcttttg tcttcacatc agaagatgaa gctgcgttac gagaagagcg gttaccacat
    18841 gcagcaagtc caactgctgc cactgcaact aggccaagac ctagccattg tttcttgttc
    18901 attactgaac ctcctaaata agatgtgcaa cgatgttgca agtatggatt gattggtcac
    18961 aaagaccctt gccactcaaa gagcgactca gactaattta agtctgtaaa agaatatgga
    19021 agtaactccc cgaccgtcat ctcgaccgtc gatttatctt ttgcgactaa ggtcactttt
    19081 aaatcttgtt caaaaaattc gaccattact tggcgacaag caccacatgg tgaaatcggt
    19141 ttttcagttt gaccatagac aatcaattct gaaaattctc tttggccttc agatatagcc
    19201 ttaaaaatag ctgttctctc accgcaattg gtcaaaggat agctagcatt ttcgatattc
    19261 actcccgtgt aaacatttcc gtctttggct actaaaactg ctccgatagg aaagtgagaa
    19321 taggggacat aggcatgttt gctggtttca attgccagtt caatcaactc agtagtcgcc
    19381 atctgccaat tctcctttta aaatagctac cccagctgac gttccgatac gggtcgcacc
    19441 tgcttcgaca aaggcaagag catctgcata agaacgagct ccaccagcag ccttgactcc
    19501 catatcagat ccaactgttt cacgcattaa tgtaacatct gctatcgtag caccaccagt
    19561 tgaaaagcca gtagatgttt tgacaaagtc agccccagct ttttgggcca attggcaaac
    19621 aacaactttt tcttggtctg tcagaaggca agcttcaata atgactttca ctaacttatc
    19681 accacttgct tccactactg cgcgaatatc tgactcaacc aaggctaaat tacctgattt
    19741 gagagctcca acattgatca ccatatcaat ctcatctgca ccattttgga tagcttcttt
    19801 tgtctcaaat gctttcacgg ctgaagttgt tgctcccaaa gggaaaccta ctaccgtgca
    19861 aaccttaaca tctgtgcctt caagcccttt tttagcatgt tcaacccagg ttggattaac
    19921 gcaaacactg gcaaagccat actctctagc ctcagacaac aaactatcaa tttgtttttt
    19981 ctttgcatct tgttttaaaa gcgtatgatc tatatattta tttaatttca tttcggtttt
    20041 ccctccattt aggagatgat ttctacaatt tcacggattt ttttcacttc atcacttatt
    20101 ttaacacatt tttggaaatc tgtaactagt tgaggtggaa ttttttcatt tgtgtatact
    20161 tttgcaacaa tttcaccctt ttgaacggag tctccaatct tcttttcaaa aacaattcct
    20221 gtttcatagt ccaaggcatc agacttaact gcacgaccag cacccagcct catggcataa
    20281 agaccaaagt ccatagctgg aagagctgaa atgacacccg tttcctgagc agggatttcc
    20341 accacatgag ctacatttac aggacgatag aggtcttcca agtctccacc ttgggcttgc
    20401 accatttcct caaacttagc cagtgcttga ccattctcaa gatgttggtg aacttcttca
    20461 acagtcttgt taacatttgc caaaccaagc ataatttgag ccaattcaca aataaagtgg
    20521 gtaatatcct gacgtccttg accttgcaaa atctccaatg cttcaagtat ttccagacga
    20581 tttccaatcg ctcgtcccaa aggctggctc atatccgtaa tcactgctac tgtcttccgt
    20641 ccaacaacct taccaagatc taccatagtt tgagccaact cacgcgcctc atcaaccgtc
    20701 ttcatgaagg caccctcacc gacagtcacg tctagcaaaa tagcatccgc ccctgccgca
    20761 attttcttgc tcatcaccga actcgcaatc aaaggaatcg tgtcgacagt tgcggtcaca
    20821 tcacgaagag catagagaag cttatctgct ttgaccagct ggtctgattg cccaatgaca
    20881 gatactccaa tatcctgaac ctgacgaata aaatcctctt gactacgttc tacttgatag
    20941 cccctaatgg actccaattt atcaattgtt ccgcctgtat ggccaagacc acgaccactc
    21001 atttttgcta caggcacacc gaagctagca acaagaggag ctaaaatcaa ggttacctta
    21061 tcgccgacac caccagtaga atgcttgtca actttcacac catcaatggc tgacaggtca
    21121 aactcttgcc cagtcttaac catattcatc gttaaatcag aaatttcacg agtcgtcatt
    21181 cctttaaaat aaacagccat agcaaaggca gacatctgat aatcaggaac agttcctgac
    21241 acatagcctt ctaccagcca ttcaatttca cttgaagtca gttcttgacc gtctcgtttt
    21301 ttttgtatta aatcaactgc tctcattctt tcacacttct aaggatatag tatcctttgt
    21361 cttttttaag gatttcacaa ttaccaaaca catcctccat cttggactta gcacttggag
    21421 ccccttgttt tttctggatg acgattgtca aattcccacc agtttccaag aaatctttac
    21481 ttttctcaat gatttcatga acgacttgct tgcccgcacg gataggagga ttggaaatga
    21541 catgatcaaa atgtccttca acttgttcat agatgttgga ctggaaaatc gtcgcttttg
    21601 cattattttt ttcagcattt ctccgagcta aatccaaggc acgagtgttg atatcaacca
    21661 tagtagcctg aactccataa gccttagcta aggacaaacc caaaggtccg taaccacagc
    21721 ctacatcaag gacagtttct ccttggttga cctcaagaca cttgagcaat agttgacttc
    21781 caaagtcaac tattttcttg ctaaaaacac ccgcatccgt taaaaaggtc attttttgtc
    21841 ccaacaactc tactctcaac tcatgaatgt catgagcagc gtcaggattt tctgcataat
    21901 acattttact catgacacta ttttaccata atttgactca aattgtaaat cgtttacaaa
    21961 ttgataataa aacgaaaaag accgaagaaa gcgagtcacg aagccatttt cttcaatctc
    22021 tttcaacact tataaataat aaaccattta gaactataaa tatcacagtc cagataaaaa
    22081 caaaaagttt atcatctata atcaggcaga ttattatttc tattgcttaa ccttaaaata
    22141 ctttattatc aacaaaattc ccaacaaaat gtttagataa aagcccaact gatacgtttg
    22201 tgtcaggatt tccaaacttg tccaaagtcg tatcaaatct tctagtgaca tgcggaagaa
    22261 ataaccctct gtcgcaatcc atttcgccca tcgtttttta gtaagacagc aattaagaac
    22321 gaacagataa agacagctgt tacaatagca tgttccatca aaaaagtaaa accgtaatag
    22381 gtttccacaa agcatctacc attatctgca ttggctcctt ttataaaagg taaagcaaaa
    22441 cttaaaataa aacagagttc caatatgtaa cgttttaaga ttttcatagt acacctccta
    22501 taagttgtga actaaaaagt cccctttata agcttataaa tcagtagaat ctatctccta
    22561 tttcatcaat aaattgatca cttatactat ataccattga cttaccacat tcaagaaacc
    22621 gctttatttt tttagctttt tatggtatga tagacaaaat atctagggga aaacaaatga
    22681 ccaacgaatt tttacatttt gaaaaaatca gccgccagac ttggcaatct ttacatcgaa
    22741 agacaacacc tcctttgaca gaagaagaat tggaatctat caagagtttt aatgaccaaa
    22801 tcagtctcca agacgttaca gatatctatc tccccttggc tcatctgatt cagatttaca
    22861 agcgaactaa ggaagattta gccttttcaa aaggaatttt cctccaacgt gaaagtaaat
    22921 ctcaaccttt tattattggg gtttctggga gtgttgccgt tggaaaatcc acaaccagtc
    22981 gcctacttca aatcctactg tcccgtacgt ttacagatgc tacggttgag ttggttacaa
    23041 ctgatggttt tctctatccc aatcaaacct tgattgagca ggggatttta aatcgtaaag
    23101 gatttcctga aagctataat atggaagctc ttctcaactt cttggatcgc atcaaaaatg
    23161 gacaagatgt agatattcct gtctattctc atgaagttta cgacatcgta cccgaagaga
    23221 aacaaagtgt caaagctgct gattttgtaa ttgttgaggg aatcaatgtc tttcaaaatc
    23281 cacaaaacga tcgtctctat atcactgact tctttgactt ttccatctat gtagatgctg
    23341 gagtggatga tattgaaagt tggtatctgg accgtttctt gaaaatgctg agtctagccc
    23401 aaaacgaccc tgatagctac tattatcgtt ttactcagat gccgattggg gaagtggaag
    23461 cctttgccca tcaggtctgg accagtatca atctcacaaa tctacaaaat tatattgaac
    23521 caaccagaaa tcgtgcagaa gtgattcttc ataaaagcaa gaaccatgaa atcgatgaaa
    23581 tttacttaaa aaaataattt tcccttgtca aaacgtaagt tttcatatat aatggtatag
    23641 ttagtaaata tggaggtaag aacattggca aacattaaat cagctatcaa acgcgctgaa
    23701 ttgaacgtta aacaaaacga aaagaactca gctcaaaaat cagctatgcg tactgctata
    23761 aaagctttcg aagcaaaccc atctgaagaa cttttccgtg ctgctagctc agctatcgat
    23821 aaagcagaaa ctaaaggttt gattcacaaa aacaaagcaa gccgcgataa agctcgtctt
    23881 tcagctaaac ttgctaaata agaaacagtc catagaggct gtttttttgt ctccaaatag
    23941 gaaaaggtag aaaatgaaaa tcacaattat cggatattct ggttctggta agtcaactct
    24001 agcagaaaag ttatctaact actactccat tccaaaactg cacatggaca cactccaatt
    24061 tcaacctggt tggcaagaca gtgaccacga atggatgtta accgagataa aaaactttct
    24121 caccaagcat aaagcttggg tcatcgatgg taattattct tggtgctact accaagaacg
    24181 aatgcaagaa gctgaccaaa tcatctttct caatttttcg ccattgacct gtctctttag
    24241 agcctttaag cgttatctta aataccgtgg aaaagtcaga gaaagtatgg cggcagattg
    24301 ccctgaacgc tttgactggg agtttatcag atggattctt tgggatggac gtagcaaaac
    24361 tcaaaaagaa aattaccaaa aactttgcca agaatattca cataaagcca ctattcttcg
    24421 aaatcagaga gagctagatc aatttctgga taagaaaagg aagtcctaca attcataaag
    24481 ggcttccttt ttggctataa ttattctgca atcaaggttt ccaaaccaac cttcatcata
    24541 tcagtgaagg tattttgacg ttcttctgca gttgtgtctt cgtctggatt gaccaagcta
    24601 tcagagatgg tcatgatagc tagcgcatca acatggtatt gggcagcaag atagtaaaga
    24661 gctgctgctt ccatttccac agccttgact ccccatttac caagctcgat attcttttca
    24721 aagtaatttg agtaaaagac atcagatgac aaaacgttcc caacgtgagt agtcatacca
    24781 agttctttgg caatatggta ggctttatca agcaaatcaa agctagcaat ttgtggaaaa
    24841 tcgtactgtg gccagtcatt acgaacgatg tttgagttgg ttgcagccgc ctgcgccaaa
    24901 actaattcac gaacatgaac ctcttcattc aaagaacctg cagttcccac acgaatcaat
    24961 ttcttcacac cgtagtctac gattaactca cgcgcataaa tcgaaataga tggcattccc
    25021 atcccagttc ccatgacaga tacacggtga cccttgtaag taccagtgta accaaacatg
    25081 ttacgcactt cgttaaaaca aacagcatca ccaaggaaat tctccgcaat aaacttagca
    25141 cgaagaggat ccccaggaag aagaatttta tcagcaattt caccctgctg agcagcaata
    25201 tggatagaca taatttatga tacaaagagc gagaagaaaa cgactgaaaa ttaggaagct
    25261 gacgagaaat cctgattttt cagtcagatt atctattttc cgagttttcc gctcgtgttc
    25321 aaatcaaaac acacgctcta cctttcttta ttttatattt tatattgaga aagataccaa
    25381 acccgtcaaa aagcgaaggg aaaataggag ttgggcgcag tgagcgatgc tcgctagacc
    25441 aactatcttt ttcccactgc ttttagggtg ggttcaattc ctttctttct taattttgat
    25501 ttagaggaga gtcgcccgta ttcagttcag cgaatacagt ttacccatcc tttcgttttt
    25561 gtttttagaa aagttttcta ctcgtgttca aattagaaca cgcgctctac ctttctgttt
    25621 atactcttcg aaaatctctt caaaccacgt caacgtcgcc ttggattata tatgtgactg
    25681 acttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacctgc ggctagtttc
    25741 ctagtttgct ctttgatttt cattgagtat taattttgtt ctttcataga gagctacctg
    25801 agttctattc aagctcaggt agtactttct tataaactag acaaactaac tgtcattcta
    25861 ccatcagatt acaagacatc atcgtcactc accttggaat tcaatgtcgt accccaatgg
    25921 gtaattttac ggtggggttg agctaaaatt ggtctgtttt catagattgt ttgccatcta
    25981 ttccatagta gacctgtctt tttctcaatc ttaactcgca gatttctcat attttctttg
    26041 attgggaggt tgaggacaaa acctgcagtc tggttgcgac cgtttccttc ccaagaatga
    26101 ctacgaacaa cttggtttcc atctttatct actggaactt cttcccaagt tatggagtag
    26161 cgggcaatgt aagctccgct gtgttgaatt gtcaatgttt tatctttcac aggagtctga
    26221 ctgattggtt gaactggctt agaaacttgt gtcgccgttt cagcattcgt agctataaag
    26281 cggaaaactt caacttctgc aagactgagg gcattatagc cttctagctc aatccgaaca
    26341 tagcgcgctt ttttatggtt aatcgtaatt tgtgctgaca catctttagg agatattatg
    26401 cgttttcact caatttcttt accagaactg tctaaaagaa tgacatcaaa gtttgccaat
    26461 ctatcctggg cagtgtctgt tcggttgtaa atattgattt ggcgaatggt ttcttcttta
    26521 gccaaatcta cttgccacca aggcttagat tggaagtttg tatgagtgac agaattgtga
    26581 ccatagttac catcgacttt gccatccaca gctcttctag catctcctcc gaaagctgtc
    26641 gaactttgag taacctgttt tcctaaggca atattttcca ttggttcagc gcttggttga
    26701 ctagaagatt gaggtagagc ctgtttctta aagaatcgca ctttatccaa tttcggatca
    26761 cgataaccat gtttatccaa ggtagcttgt ttaccaatat taaagttagg aatatcattc
    26821 attggacttt caaaatagcc acgagaacgg tgtttaaagc gtgaattacc tgtaaatgta
    26881 acaatatcac gattattatg aatcaaggga gtcacaacat tgtcattatc aaccacataa
    26941 tgcttaattt ttccactaac agctaattta cgactttcca aaccaacatc ccagaaacca
    27001 ttcttagcat tccaaacagt tctggaagta atcactttag gagcactgaa agttgtcact
    27061 ttcctcaata catggttata aaaatcagga tatttttggt aagcttcaac cgctgcaatc
    27121 tgagctaggt aacatccaag agaatgacct gtcatataca acttagtaat acttatatcc
    27181 ttggctaatt ccccaacaac cttgcggata tcatccgctt gagctggtta tgttatctct
    27241 acttttgact cttccctttt gttttcaaga acttcacttg cttccggaag cgtttgagga
    27301 gctagtcttg gctcctctct aagaggagtt tctagttttg gagcatcatt ttctgactct
    27361 ttcaattcct ccttagaatc tagcacacct attaccactt cagatgttac atcttgcttt
    27421 acttcattgg ctgaaattcc agctggagct agaaatcaaa gccgactaca acagatacaa
    27481 ctccgatact taatttttta tgccaaagcg cataattcgt tgaccaattt tcattatttc
    27541 ttatctttct tttcgtttat ttacaagcag actcaagcga aatctcattg tgctatatat
    27601 gataagactg agaaattcag aaagtcaatt cattctcatc tctccttatc atactagtct
    27661 gcttggctag gaagctaatg ctagtatcct agaatcttgt ctttcacaat gctggctatc
    27721 agatcagaca tacctattct tccgcttctt tcagttataa gagcaggaag aagctcatag
    27781 tattcctctg tttcttcttt aatccggata ggcagtcaat cctgaaaaga cagaggcact
    27841 acccctttta aatctttttt cttacaattc agcaagaatc gctttaagca agcctttgaa
    27901 atcaccttta acacgttcag tcacttctac aacttcttcg tgattgagtt cttcttggaa
    27961 accagccgca aagttagtga tacatgaaat tcccagaact ttcaagtcag agtgggctgc
    28021 cacgataact tcaggaaccg tagacatacc aactgcatct gctcccagtg tcttatagga
    28081 acgaatttct gctggtgttt cataagtcgg accagtaact ccgatataga caccttcatc
    28141 aagcttgata ttaagttttt tagccacttc atgggcagtg gcacggtatt ctggtgtgta
    28201 ggccctagac atatctggga aacgtgggcc aaagtcatcc aagttttcac ccatcaatgg
    28261 attttgcccc gtcatgttga tatggtctga gatagccatc aaggtaccag gaccaaatct
    28321 gataccgcca gctgcattgg ttacaataac accttcacat ccaagaactt tcatcacacg
    28381 aactgggaaa gtcaccactt ccagaggatt cccttcatag aaatggaaac gaccttgaag
    28441 agccaagacc ttgcgacctg ccagttcacc atataccaat ttaccagcat gaccgactac
    28501 tgttgaacgg ccccagtttg gaatctcagc atagtctact acaactggat tttcgatttc
    28561 ttctgccaat tctccaagtc ctgatccaag gattagaccg aactcagggg ctgcaattcc
    28621 cttttctttc aggaaagtag cagtttcatg gattttgttt aaaaatgtca ttgtgtgtct
    28681 cctttattat ttttttagca tttgaccaat tttgtcaaag gttttagcat tacgaatagt
    28741 aatgtggcgg tagaaaggca ccttcagcaa gtacttatga taggcagtct tagaatagga
    28801 ttcttcagaa aatcccaagt tttccaaaat aaagcacttc atctttcagc tctaaacttt
    28861 caactgtcgc gatgacttgg tccacatcca aaccctcagt gtaaaagaga aaatcttttc
    28921 gtgccaagtc tctgctccac caagctggta gattttcaag ttccgcctca aagtcctcta
    28981 gactcagtaa agaaaagctc tgaataaatg gataatggac tgcaaagaaa gtctctagct
    29041 tttcaaccaa ttgggctttg gaatctatcg aagtaaagaa aatattgcca ctgttgatgt
    29101 agctctcaac cttttccagt cccaagtttg tcaattcttg acgaagctcc gccatgacga
    29161 ccttattctt accaccaaca ttgatacctc tcaccagcaa agcatagcgc gtcatcttat
    29221 accaatttat ctaagaaact ttccccaatc atagcagttt ccacaccaaa gttatcggca
    29281 acagtcgctg aaatatctgc aaaatgtcct actggaatga gaccatttcc tttaaaggca
    29341 gggctatagg ccaacaatgg aatatattcc cgagtgtgat ccgttcctgc atacgttggg
    29401 tcatttccat ggtccgcagt aatcaagaga aggtcattct ctctcatagc tgcgataatt
    29461 tcaggtaagc gttcatcaaa ctcatgcaag caatcacggt aaccgtgagc attacgacga
    29521 tggccgtaaa gggcatcaaa gtcaactagg tttgtgaatg agaatccttt ttcaaactca
    29581 gcaagtccca tagtcttcaa tagtgtatca attccatgac tatttgactt gttgtgaccc
    29641 atgtcatggt tgataccagc accgttaaag atatcgttga ttttacccac agcataagta
    29701 tcgataccag cctcattcaa tttatccaaa acagttgggg aaaatggaga tacagccaag
    29761 tcacgacggt ttgccgtacg agtgaagtta cctggttcac ctacataagg gcgagcaatg
    29821 atgcgaccaa gaagggcagg acgctcaagg gtaatcgaac gagcgtattc acagatacgg
    29881 tacaattcat ccaaaggaat aatatcttcg tgggcagcaa tctgcaaaac agggtcagct
    29941 gaagtataga taatcaactc tccagtttcc atctgacgtg gtccaaaatc atcgataaca
    30001 gccgttcctg aataaggttt gttggcttca cgaataacct tgcgtcctga gaattcttcg
    30061 atttttgtca ggatttcttc tggaaatccg ttccagaaag tatcgaaagg ctcagtaatg
    30121 ttgagtccca tgatttccca gtgtccagtc atagtatcct taccaagaga tacttcctct
    30181 aattttgttg catatccagt tggattgctt tcagctgcta cagtcttaag aggagtttca
    30241 cgaggaatat ttccaagacc tattttagcc atgtttggga cattcaaacc aactgttttt
    30301 gaaatgtgtc ccagtgtgtc agaagctcca tctggaaccc ctgcattgac aaagttatta
    30361 gcatctggtg ctgcaccgat tcctacagaa tccagtacca ccaaatgaat acgattaaat
    30421 ttagacatct tatgccccct tctattttcc tttttttgaa gttgaaatct gaactccatc
    30481 tcgtccagca acgatgacct tatccaccat ttggttgaat aaaccatgct ccacaacacc
    30541 aacgacatgg tccaattctt gtccaaaagc aattggattt tcaatgacat ccaaggcgag
    30601 gtcaatgata aaattctgca tatccgtcac aaaacgttgg ccgtcttttt cacggaaact
    30661 tggtttgtag ccagctcgtt caaaatgacg aaagacctgc tctgcaccat actgaaccac
    30721 ttctactggc aatttaaaag cacctagttt ttcgaccagc ttgctttcat ccaccaccca
    30781 aatgtattct tttgatggtg ttgcgaccac cttttccatg agaagggcac caccaccgcc
    30841 tttgattcca ttaaactgac tatccacttc atccgcgcca tcaaccgtca catcgacaaa
    30901 gtctacttgg tcaatagact tgagcgggat attaaggcct tctgcctgtt tagtggtcac
    30961 actagaagtt gttacagctg taatctgcaa tccttcttcc ttgatacgac gaccgatttc
    31021 ttcgacaaaa taataggcag tcgagcctgt tccaagtcca acgaccattc catcgctcac
    31081 gaactcagca gccttgatac ctgccatttt cttcagattt tccaccgatt tacctccatc
    31141 attctcagtt cttattttac tatgaaaccg ctttttattc aagtaaaaac atcaaatcta
    31201 catttttcat caatctttct ttaaaaatat gtattttctt ttcaccaaac gaataaaaat
    31261 gagtttatct tttatgtatt tgatttgttc atctctttcc agttacaaaa acaaaatctt
    31321 aactttgata cgtctagttt agccttaaag caggcgcatt tcaagaatca taaattaaga
    31381 gaaggaaata gatttatctg tctattttaa acaagtttat ctttgcttac cctctcttgt
    31441 tgacaaataa ttttcattat tttgggaaga tacctgctga tttccgtcgg taagaccaca
    31501 taattttctt gagatagttc ttgggctatg gctgaatgaa gatgggtcgc tactgccaca
    31561 cgctcgtaga gactggcctg tcggaattgg cctacaaatc ctgcgatcat cccagccaga
    31621 gtatctccca ttcccccagt cgcctgataa ggaccaccaa cctgtaactg gtaataatca
    31681 gattggccaa cttcccaaat acgagtagct gggcctttct ccaccaaaat tgttccttga
    31741 gggaaagaag gcagaacact agccgttgca tcttcctttt gcttttcaat cgtaattcca
    31801 gataattttt cccattcttt ttggtgagga gttaggataa gctggcttga gggaaatgac
    31861 aaacttgtcc tagcaagaat ggtcaaggca cctccatcta caatcaaaat ctgattttgg
    31921 cttaaattaa caaagacctg ttttactaga ttttctccag aagcatcgtc tcgtaaacca
    31981 ggccccagca agacaacttc tgccttctcc aattgctctt ttaacaattg ctggtcttga
    32041 agagaaaagg ccataggctc aggtaaatgg ctgtgcagag ccgggatatt ttccctgtcc
    32101 gttccaacgg tcaccaatcc tgcaccgctt tttacagctg ctaaagcagc catgatgatg
    32161 gcacctccat aaggataagt accaccaagc agcagcagac gaccataatc tcctttatga
    32221 cttgaacgag aacgttcaat aataactttt tctaataagg tttgattaat cactttcatt
    32281 cttttttcct ctcactttta ttatacaata aaaaggagac gcagacctcc ttttgtaatc
    32341 ttatatctaa aatttaatat tcatttctgc cattttagat atagctatag aaaatacact
    32401 ctattaatcg aatgtttctc ttattttcta tccaatgtcc gaagtgctgc ttgataagtt
    32461 tgctccatca gcatggtaat ggtcatagga ccgacacctc cagggactgg cgtgatatgg
    32521 ctagcaagtg gtgcaactgc ctcataatca acatctccac agagcttccc attttcatct
    32581 cgattcatcc caacgtcaat gacaaccgca cctggtttga caaagtcagc agtcacaaac
    32641 ttggcgcggc cgattgcgac tacaagaata tctgctttag cagccacctt ggcaagatta
    32701 tgagttcgtg agtgggccaa ggttactgtc gcatttttag ccaaaagaag ctgagccata
    32761 ggttttccaa cgatatttga acgaccgatt acgaccgcat ttttaccttc caagtcaatc
    32821 ccatattcat gaaacatttc cataattcct gcaggtgtcg agggaatcat gactggatgt
    32881 ccagaccaaa gacgtcccat gtttagggga tggaaaccat ccacatcctt ttctgggtca
    32941 atggctaata aaaccgcctc ttcatcgata tgttttggta atggcaactg gaccaaaatc
    33001 ccatgccaag ctggatcctg attatattta gcaatcaggt ctaacaattc ctcttgagta
    33061 atggtctctg gaactcgcac tacttcgcta cgggaaccag ccgcaagagc tgacctctcc
    33121 ttgttgcgaa cgtagacttg gctggctgga ttatccccaa ccaaaatcac taccaaacca
    33181 ggcactagag ttgtttcttc ctttaatttt gcagtctttt cagccaactg cccctgcaat
    33241 ttggccgcta aagctttccc atcaataatc tgtgtcatat cacttctctt ttctttcaaa
    33301 tatcttccat tataccaaaa actgctagtg ccctctaaca cttctttcct aggttatcct
    33361 atagtttcaa actataagaa aaagctctgg ttgaactttt cactaatctt gtcttgaaat
    33421 tttaaaatag attataaaac cttactcaag aaatctttag tccgttgttc ttgggtttgt
    33481 tcaaaaatct gctcaggtgt cccatcttca acaaccacac cgtctgccat aaagataaca
    33541 cgatctgcca cctcacgggc aaatcccatc tcatgtgtta cgataaccat agtcatccct
    33601 gacttggcaa ggtcttgcat aacagccaat acctcaccta ccatttcagg atccaaggct
    33661 gaagttggtt cgtcaaagag caaaacatct ggttccatag ccaacccacg cgcgatggca
    33721 atccgttgtt gttgcccacc cgacagactc tgtggataag cgtctgcctt atctggcaaa
    33781 cccacttttt ccaaaagctc ttgggatctc ttctcagcaa cttccctgct ttcaccttta
    33841 gtcttgatag gtgacaaggt aatattttcc atcacagtca tattaggaaa gaggttaaat
    33901 tgttggaaaa ccatgcccat cttctcacgc atggcaaaca ggtcattctt cttgtccgta
    33961 atatcgactc cctcaaagat aagcttcccc ttggttgctt cctccaacaa attcatagag
    34021 cgaagcaagg tagatttccc actccctgaa ggaccgatga taacgacaac ttctcctctt
    34081 ttaatctcga ggttgatgcc cttcaatact tcattctttc caaaagattt atgtaaattt
    34141 tcaattttta tcaaggtttc tgtcattatt tcttatctcc ttgtcccata tgtttttcaa
    34201 aagctttcaa ggctactgtc agaatagagg tcataatcaa gtagtaaaat gctgcaaata
    34261 aaagtggtgt taaaggtaga taggttgttg tagaaactgt tgtagcccca ttccacaact
    34321 ccatgacccc aatagctgat aagagggagc tgtccttgat aatggtgata aattcgttcc
    34381 ccaatgctgg caagatattt ttgactgctt gtggcaaaat cacataacgc atcgcatttt
    34441 taggacgaat ccctagcgaa taagccgcct ctagctgacc ttttggaacc gcattgattc
    34501 cggcacgaac agtctccgaa acataagcac cactattcat agagataatc aaaatccctg
    34561 gaatcagacg cgaaaaatca acacctaaaa ttccaatctg aatagtcgga gcattgatat
    34621 gcataagagc aaaggcaatc ataatttgaa ccatcatcgg tgtcccacgg aaaatccaaa
    34681 cgtacaagtt ggccaaccaa acaagcggtt taaactttga acgttgccca aaagccaaga
    34741 caacacccaa aatagttccc aaaaagataa cacagataga aataagaatc gtcacaacag
    34801 ccccatagtt aaaataaggt aaatacttag gtaaaaaaga aaaattcata gtcacactgc
    34861 tttctaaaat agaatactgt atgattataa catgttttga attaaaattt aaatttttta
    34921 tccaatttat ttaaaaatct ttaaactagc agaattagcg agaaatctta gtttttttct
    34981 agtcaagttg gcctccttta tggtaaaata gtaacgataa gaaatgaagg agaatcaaaa
    35041 tggaatcaca tttggttaga atcatcaacc gccttgaagc aatggcaaac gatggcggaa
    35101 atttaaaacg taattttgaa cgcgaaggag ttgttgttgc agaagttgcg tacagccacg
    35161 acgaagaaaa cggcccaatc tttacccttc gtgacgtaga agatcgcgaa acgtatacgt
    35221 ttgatagcat tgacttaatc gcaatggaaa tttacgaact tctctactaa tctaaaacaa
    35281 gctgggattg tccctgcatg tctaagtaaa atcctttttg tctcacaaat aggatttttt
    35341 tatagtccaa attcacaaaa attttcattg taacaacttc tcaaagcttc aatcttttta
    35401 cttgctttac accccaatcc tgttataatg agagtataga atttgactat ttttgacctt
    35461 taaacaagtc aggctaaaga aagaaatgag gtagatgtat gctttgtcaa aactgtaaaa
    35521 ttaacgactc aacaattcat ctttacacca atctcaatgg aaaacaaaaa caaattgacc
    35581 tctgtcaaaa ctgctataag attatcaaaa cagatcctaa caatagcctc ttcaaaggta
    35641 tgacggatct gaacaatcgt gacttcgatc cctttggtga tttcttcaat gatctaaaca
    35701 atttcagacc ttctagcaat actcctccta ttcccccaac ccaatcaggt ggaggttacg
    35761 gtggaaacgg cggttatggt tcccaaaatc gtggatctgc tcaaactccg ccacctagcc
    35821 aagaaaaagg cctgctggaa gaatttggta ttaatgtaac tgaaattgcc cgtcgtggag
    35881 acattgatcc cgttattggg cgcgacgatg agattatccg tgtcatcgag attctcaatc
    35941 gtagaaccaa gaataatcct gtccttatcg gtgaacctgg tgtcggaaaa acggccgttg
    36001 tcgaaggtct agctcagaaa attgtcgatg gcgatgtgcc acataaactc caaggtaaac
    36061 aagtcatccg tctggatgtg gttagcttag ttcaaggaac ggggattcga ggacaatttg
    36121 aagaacgcat gcaaaaactc atggaagaaa ttcgcaaacg tgaagacatc atcctcttta
    36181 tcgatgaaat ccatgaaatt gttggtgctg gttctgcgag tgatggtaat atggacgcag
    36241 gaaatatcct caagccagcc cttgctcgtg gagaactgca actagtcggt gctactaccc
    36301 tcaatgaata ccgtatcatt gaaaaggatg ctgccctcga gcgtcgtatg cagcctgtta
    36361 aagtcgatga accaacggta gacgaaacaa tcactattct caaagggatt caaaagaaat
    36421 acgaagatta ccaccacgtt caatataccg atgctgcgat tgaagcagct gcaactcttt
    36481 ccaatcgcta catccaagat cgcttcttgc ctgacaaggc cattgacctc ctagatgaag
    36541 ctggttctaa gatgaacttg accttgaatt ttgtggatcc taaagtaatt gatcagcgct
    36601 tgattgaggc tgaaaatctc aagtctcaag ctacacgaga agaagatttt gagaaggcgg
    36661 cctacttccg cgaccagatt gccaagtata aggaaatgca aaagaaaaag atcacagacc
    36721 aggatactcc tatcatcagc gagaaaacta ttgagcacat tatcgagcag aaaaccaata
    36781 tccctgttgg tgatttgaaa gagaaagaac aatctcaact catccatcta gccgaagatc
    36841 tcaagtctca tgttattggt caagatgatg cagtcgataa gattgccaag gctattcgcc
    36901 gtaatcgtgt cggacttggt acccctaacc gcccaatcgg aagcttcctc ttcgttgggc
    36961 caactggtgt cggtaagaca gaactttcca aacaactggc tatcgaactt tttggttctg
    37021 ctgatagtat gattcgcttt gatatgagtg aatacatgga aaaacatagt gtggctaagt
    37081 tggtcggcgc tcctccaggt tatgttggct atgatgaggc tggtcaatta actgaaaaag
    37141 ttcgccacaa tccatattct ctcatccttc tcgatgaagt ggaaaaagct cacccagatg
    37201 ttatgcacat gtttcttcaa gtcttggacg atggtcgttt gacagacggg caaggacgca
    37261 ccgttagctt caaggatgct atcattatca tgacctcaaa tgcaggtaca ggaaagaccg
    37321 aagctagcgt tggatttggt gctgctagag aaggacgtac caattctgtc ctcggtgaac
    37381 tcggtaactt ctttagccca gagtttatga accgttttga tggcattatc gaatttaagg
    37441 ctctcagcaa ggataacctc cttcagattg tcgagctcat gctagcagat gttaacaagc
    37501 gcctctctag caacaacatt cgtttggatg taactgataa ggtcaaggaa aagttggttg
    37561 acctaggtta tgatccaaaa atgggagcac gcccacttcg tcggactatt caagactgta
    37621 ttgaggacac aatcactgac tactaccttg aaaatccaag cgaaaaagat ctcaaagcag
    37681 ttatgactag caagggaaac attcagatta aatctgccaa aaaaactgaa gttaaaagtt
    37741 ctgaaaaaga aaaataaatc ctatagaaaa ggagtagaaa atgaaatttt tctgcttctt
    37801 tttttactaa aataactgta atttcttgac agcttgccct ttgtccatta tgatatatag
    37861 tagactgaat ctgaaatagt acgaaacaat tgctaaaaca tttatagaaa ttaattttac
    37921 tttccaaatc gatttgttct catcttattt caatctgcta tagtcaattg aaacaagaac
    37981 aggacaaaag agcctcgtaa aaggtattgc aacttggtaa tacctttttg aggtgctttt
    38041 tgatatgagc ccatgttttc tcaataggat tgtactcagg tgagtaggga ggaagaggta
    38101 aaagtttatg cccaaactct tcgcataaaa gttctagctt ccccattcta tggaatcttg
    38161 cattatccat aatatagtag attgaaacta gaatagtaca catctacttc taaaacattg
    38221 ttagaattcg attttactgt cctgatcgat ttatcctatt cttattttat tttactataa
    38281 taaccgatgg tgtggttaat gttggtaaga gaaacttctg aaaccaagct tcaaaaaagt
    38341 cgctcgtcat cgtctcttcg taagtcattg gagcgattaa ctcaccattt gttagacctg
    38401 caaccaaaga aatcctctga tatcttcttc cagatacttt gcctcttatt aactgacctt
    38461 ttaatgagcg accatattct cgataaaaat aagtatcgaa tcctgtttcg tcaatctaaa
    38521 caggtgctag gtgctttaaa ctattaaaat tcttaagaaa taaggctact ttttctgggt
    38581 cttgttcata gtaggtgtgg ttcttttttc gagtgtagcc catagctttg agcgcatagt
    38641 ggatggtagt tggatgacag ccaaattcag aagctatttc agtcaaataa gcgtctggat
    38701 tgtcagtaag atagttttta agtctatctc tatcaacttt tcttggtttt gttcctttta
    38761 cttggtggtt tagctctcct gttttctctt ttagctttaa ccagccataa atggtattac
    38821 gtgagatttg gaaaacgtgt gatgcttctg ttatactacc tattcgctca caataagaga
    38881 gaactttttt acgaaaatct attgaatatg ccataagaag attataccac attgtgtact
    38941 atttttggtt catttcacta taataataac gatactagat aatgaggaaa atgcaatggc
    39001 aaacccaact ttcggagaaa aaagcgaata cagactatat tgctcgctat ggcgtacatg
    39061 cagttatccc taatcctgaa caaaaacaaa ttgttcttgt tcaagaacca aatggtgctt
    39121 ggttcctacc atgtggagaa attgaagcag gtgaaaatca tcaggaagcc ctaaagcgtg
    39181 agttgattga agagcttggt ttcacagcag aaattggtac ctattacgga caagctgacg
    39241 aatatttcta ttctcgtcat cgtgatacct actactccaa tcctgcctac ctctatgaag
    39301 caactccttt caaagaagta caaaagccac tagaaaactt taatcatatt gcctggttcc
    39361 ctattgacga ggctatcaaa aaccttaaac gtggtagcca taaatgggcc attgaatctt
    39421 ggcaaaaaca gcataagatt ggctaatact cttcgaaaat aaaattcaaa ccacgtcagc
    39481 gtcgccttac cgtactcaag tatagcctgc ggctagcttc ctagtttgct ctttgatttt
    39541 cattgagtat aaatcaagcg actttattca aaaagtgcta taatagaatt agaaaatcgg
    39601 aggaaatatt atgaagctta tcaatacgac aaactcacac tcgcaacttg taaaaagtca
    39661 gctagaaagt accgatgcaa cccttgttga ggtttattct gcagggaata cagatgttat
    39721 ttttacccaa gctccgcttc actatgaaat cctcatctca aacaaacacc gtgctattcg
    39781 tgagcctgaa atcgaaacca ttcaagaatt tttcttgaaa cgtaaaattg ataagacctc
    39841 tgttgatgaa gccaatatca agacactcta ctcagagaaa ttaattggaa tttcaatccc
    39901 aatcaagtaa gaaaattgag taaaaactcg atttgagaga aagtccaata agtctttcca
    39961 taacaaaacg catagtaaca agagtttcta cacccactat tatgcgtttt tatcattttg
    40021 aaatctactg ctaatcaatg aagaagcaaa gatcaaacta ggcagctagt tacaagttac
    40081 gtaagcgcgt cataacaagg tatctatcct aattccccaa cttccagtat actagataaa
    40141 aaataattat cggaggaaag gtattgtact atgataattc aactaagtga tttaggtcaa
    40201 gttcaccttg tttgtggtaa gacagatatg aggtagggaa tagactcatt agcctatgta
    40261 gttaaaaccc actttgaatt ggattctttc tccggtcaag tctttctctt ttgtggtgga
    40321 cgtaaagacc gctttaaagc cctttactgg gatggtcaag gattttggct actatataaa
    40381 cgctttgaga acggaaaact gacttggcta agtacagaaa aggatgtcaa agctctcgca
    40441 cctgaacaag tagattggct gatgaagggc ttttctatca ctccaaaaat atagtagatt
    40501 gaaactagaa tagtacacct ctgcttctaa aatattgtta gaaatcgatt tgactgtcct
    40561 gatcgatttg tcctgttctt gtttcgtttt actatagaac gatttgaagg cgtttatgat
    40621 atttagctgt acgagagtct tttaaaagtg ttttgatggt ttggatttct tctttagttg
    40681 attttatatt actattatat aatacttttt tattttagtc tagtataaat agcgagaaat
    40741 atctatccta tcttctagaa tgtcttccaa acgagaaaac tctcgtaaac aaagaggttt
    40801 tagaggccta tttaccgtgg actaaagttg tacaagaaaa gtgcaaataa gaaatctcca
    40861 gattaggaac tatccgtgag ttctctagtc tggagatttt tcaatagact tcgttattgg
    40921 acggttacca agttactcaa agtacagatt tgaagctgca gataagactg acgaaatcac
    40981 tttaatacta aatgaaaatc aaaaagcaaa ctaagaagct agcctcaggc tgtacttgag
    41041 tacggtaagg cgacgctgac gtgatttgaa gagattttcg aagagtataa aacactgttt
    41101 tgaggtggtg gataaatcgg ctgagtaaaa actcaatctc aggagaaaat gaagtaaatc
    41161 tccccacaac tatagaaaaa gatttgattc tgctcctcac acaataaaat ctttttcttt
    41221 tattaaaaac gaatcgtttc acgtgttttc tcatatgagg taacaaagcg attggttaca
    41281 ccaggctctg ccacttccaa tgcttgagaa atcttgtcaa atgaagcgtg ataatcaaat
    41341 tctttttcaa aaatatctaa agcttcgtta aatgcttctt gaatgcgttc atcaaatgag
    41401 cgatagcggt tagaatattg caagagttgc tctgtcaaag ttgcatattg tacaatatta
    41461 taagtttccg tttctaaagc ttccatatca ttcgttgcaa tttcaagaac tcgggtaaca
    41521 gattcaatgt taatcatttt ttgttctaac tcaaccatta aatcctcggt attattgctt
    41581 gccgtaaaga ataacttcaa gaaagtttgt ggaatacctg gcagattgcg tttttccatg
    41641 tatcgcttga tagtatggag acgattgaca taaacattgg ccttttgacg tgcattaata
    41701 tcatctttct caatttgtgt caggcgctca ctaactgaaa tttgctcatc ttcaatatct
    41761 tttagttgag tttgtaaatc ctcaagattt tcttcaagaa ctgaataagc ttgggttggt
    41821 tcttcttgat ttgaagttac ctcaacaata gctgcctcaa aactctctaa ttctgtctga
    41881 atacgacgaa catggcttgc agctgtctca ggaagtaaat aggtcttgtt caaacgtgca
    41941 atatcttctc ccaataaagt attattctct ttcatatgtt gaaggtaagt tggaagagtt
    42001 gcaagtagat tttccactac tttctgagca gcaatttctc gagtaaaaat atcatacaag
    42061 gcattgattt cctcttgtgc ctgtccattc tcatattcgg cattatccaa ttccaactga
    42121 cgaatattct cttggttttt cttgaatgct tcataaagca agtggaaacg cgcttcaata
    42181 tccgtttcaa caaaatgata attagcatca attagtttac gataaccggc ttccaaatcc
    42241 tgtaattgat ctggcaattc tgtagaaagc gtcgtaacca aggctggaac acgatccaca
    42301 atatgactta aggccaaaat gtgattttct gtattatcca aaatcactgc ggcttccaca
    42361 gggtcacccg atgaattcaa ggttacaaat tgtgaaaatt cagattggat attttctaat
    42421 tgtttttcaa tttcatccaa ggcttgacca tactgttctg aattttcagc aactctatgc
    42481 tgaagttcct caaataaatc caaagcatga agaacacgac cactattttt agattcttgc
    42541 ttctctaagt ctgccaaagc attgcgaatt gccgcaatat cttcttcaat caaagtaatt
    42601 tgactctcaa tttggtcaat ttgatgactg gccttgagaa aacgaaatga atggttatag
    42661 ccttctgctt caaagagatt attttcaata tcggcaaaag agttgagaga taaatcgacc
    42721 catttttgat tccattcacg gaaagccact tgactttgtc caatcaagtg catatttttt
    42781 acagcttcta cttcatcatt tactggaaga ttgtatagtt cttcttttct ttcttctagc
    42841 gcctctaatc tcccctcgtt tcgcttacgt agaaagattg ccactacata agccagaact
    42901 aaaatgactg caattgcaac cattaaataa attagttgtc cattagacat atcaaactcc
    42961 ttttttactt gaaacaatcg taacgattat atcatatttt ttagaccaag ggaactactt
    43021 ctccctattt tttagacatc aagtgtacta tagacagcat tttcttcgat aaactcacga
    43081 cgaggctcta ctcgatcccc catcaacata tcaaagattt tatctgcttc tgcagcatca
    43141 tctacagaaa ctctagccat caagcgatgt tcgggatcca tggttgtttc ccacagctga
    43201 tgatcgtcca tttcacctag ccccttataa cgctgaatag tcggtttggt acgaccttca
    43261 ctataacggg ctaaagcttc ttggagtttg atttcttgat ctgcacccgg ctggatatat
    43321 tctttaatct cgcttccaac cttgacacca tagattggtg gttgggcaat ataaacataa
    43381 ccagcttcta ggattggttt catataacga taaatcaagg ttaaaagaag ggtacgaata
    43441 tgggctccat cgacatcggc atcggtcatc aaaacgagtt tttggtaacg ggctttcgaa
    43501 acatcaaatt ctgcgccaaa tcctgttccc atggctgtga aaagactacg aatttcttcg
    43561 ttagctagaa tcttatccat acttgctttt tcaacgttca aaatcttacc gcgaattgga
    43621 aggatagcct gaaactcacg gttacgacca gatttggctg atccaccagc tgagtctcct
    43681 tcgacgatga agagttctgt ttcagcaggg ttattagaag aacagtctgc tagtttccct
    43741 ggaaggttgg aaatttccaa accagatttt ttacgtgtga cttcacgcgc acgcttggca
    43801 gccacacgag ccttggcagc taaaatccct ttttccacga tacgtttggc aatctgtgga
    43861 ttttccatga ggaaatcgga gaaggcttca ctgaagaggc gattggtaat cttgaccact
    43921 tcgctatttc ccaatttggt cttggtttgt ccttcaaact gtggatttgg gtgtttaact
    43981 gagataactg cagttaatcc ttcgcgaaca tcttcccctg ttaaattatc ttcattgtct
    44041 ttcagtaact tattcttacg agcataatca ttgataacac gagtcagtgc cgtacggaaa
    44101 ccttgttcat gcgttccacc ttcatgggta tgaatattat tggcgaaact catgacattt
    44161 tcatggtaac ctgttgtgta ctgcatggct acctcaactg taatatcatc catctcaccg
    44221 tctgtataga ttggtgtatc aaagattaca tccttgttct cgttgatata ttcaacgtaa
    44281 ctagcaatcc caccttcata atgataatgc ttggtttgtt ccaaaccttg gcgcttatca
    44341 gtgatagaaa tttgaagacc gcgatttaga aaggccaact cttgaatccg tttatttaat
    44401 ttatcaaaat caaagattgt tgtttcagtg aaaatttctg ggtccggtgt gaagtgaacc
    44461 gttgttccag ttctatctgt atccccaacc acctcaaggt ctgcaacaac atgaccacga
    44521 cggtattctt ggtaatgaat cttaccgttt ttatggacat gaacgtctaa ttgagtggaa
    44581 agggcattaa ctactgacga ccccaccccg tgaagaccac ctgaaacctt gtatccacca
    44641 ccgccgaact ttcctccagc atgaaggact gtaaagacgg tctcaacagc aggacggcct
    44701 gttttttcct gaatatcgac tgggatacca cgcccatcat ccacaacagt aatcgaatca
    44761 tctggctcaa taaaaacttg aatatggctg gcaaatcctg ccaaggcctc gtcaattgag
    44821 ttatcaacaa tttcccagac tagatggtga agaccttctt ttgaggttga tccaatgtac
    44881 atccctggac gcatacgaac agcctctaag ccctctaaaa cttgaatttg actggcatca
    44941 taatcctgtg cctgcagatt tttgatttct tctgtcatct tattcctttt tcttatatgt
    45001 ctaatacttg tcttaaattc acgatactgg taaacaagtg ggtatcaagt cctgcagctt
    45061 gacctgcttc gatatcaatc ggccgatcac caatgacaag accagagcta atctgatact
    45121 tttctcttaa ataaagcatg gattcgggat ttggctttct cttaaagcct gagctagaag
    45181 tcaccacttc tgtaaaataa gctgctatag aggttttttc taaaatttcc aaaacctgat
    45241 catttcgatg agagaccaaa aaatgacggc caccttgatt taaaatgtct tccaataggt
    45301 cagaaactcc ttcaaataaa atcgggtgtt caagctctct ggcttcattt tccttgtact
    45361 tttctaaaaa attctctaaa ttgggagcga atgtctcaat cgcaaaagga gtagaaacct
    45421 ttaaagcttg atagacactg tcatggtctt gtgtgatacc atacagtgcc aatgtttcaa
    45481 caaatgcagc tgttgaagtt tcataattat ccagtaaagt tccacctaaa tcccagatgt
    45541 aatcgtgata tttcataccc ttcattatag cattttttta tgaaaaaagc gatgatttcc
    45601 ctgagttttc cacataaaaa acgagagaat aactcccgtt ttactgattt ttaccaaaga
    45661 catctcgata gagcattcct gttcgtaaac tctctgcgtc ccctcctagt tgctccacca
    45721 actcgtaggc aaaggcaagg gctgttgaag gaccccgact ggttgtcaac tgaccatcta
    45781 ccactactgt ttccttgacg tagtgaccat caaggatttg ctcttgaacg ccgtcataac
    45841 aagtgtatcg cttatttttc aatatctctg cttgattgag ggcaattggt gccgcacaaa
    45901 tggctgctag tttcttccct tcttgctcga agctttgcaa ttcttgaatc aaggtctgat
    45961 tatcacgtaa atgtgcagaa ccaggcatac ctccaggaag aacaatcata tcatagtctg
    46021 ataaatctcc atcaaagaca tgatctgctc ttacttggat tgcatgcgaa cccgttactt
    46081 gctcttcaaa accaaccata tcacatgtga tattggctcg acgcaagaca tctacaactg
    46141 tcaaggcttc aatttcttca aagccctgag ctaacataac tgctactttt accatgattt
    46201 tctccttatt taatttgttt taatacaacc tttttccgtt tgaatgggac ttttccgctc
    46261 ttttcttcag ctagattagt ctggtaactc atcgataaaa gcaaaccaac accaatcaga
    46321 ttactgataa tagctgatcc cccttgcgaa atgaaaggca agggaatccc cgtcaaagga
    46381 agtagtccag tcacagcacc gatattctca aagatgtgga agagcaacat cataatcaaa
    46441 cctgtggaaa tataagtgta gaactggtta tttgatttaa gagtaatctt caacatacgg
    46501 taaatcaaca tgagatagag ggcaataacc aggacagagc caataaagcc aaaatcttct
    46561 gcaataaccg taaaaatcat atctgactct cgaactggga taagcagatt cgaagcatta
    46621 aatccctgac caaataagcc accactccca atggcaatct gcccttgagc ctgctggtaa
    46681 gtcgttgttt gggcaaactc aaagggattg agccaagcca aaatccgatt gatttggtag
    46741 gtcggcattc caatctggtg aagaaaagct cgtccgtcct tgctaataaa gatagctaag
    46801 aaaccagcaa ctcctgttac agcagtcaca aatactggga taataatttt ccaagaaacc
    46861 cctgataata aaacgattcc tgagaaaatg gctacaaaaa ccaaagccgt ccccaagtca
    46921 ctttgaagtg ctaaaagaac taggactgga atggtaaaga gaatcatcca gaaaattaac
    46981 aaaaagtcca gcgaaaccgt gcgtctccat tccttatgtt tctttgtaaa ttggacaatg
    47041 acacgagcca acatgaggat ataggatatc ttcataaatt ctgacggttg aaatagggta
    47101 attccattta ttgataccca gtttttggca cccgttgatg caactaagct tggattataa
    47161 aatacaatcg gcaagatcat aagtcccaag cctaaaatat atagaaaggg ggtcaccttc
    47221 caaagaaatt ctgtattaaa gagcatgacc acaaaaccaa tcacaagccc caaggcaatc
    47281 caggcgacct gctgccctaa aatgggcaga atattattgg gataatcatg actaacggct
    47341 atatagatag ccaccacacc gatgaccagt agaaaaaata ctggcaagag caaactgtaa
    47401 tcgactcttg agtcgagaga acgtttcata tatactaacc ttatactttc atacaatact
    47461 atttatcaaa gttcattaaa aaatctatca atagcctcgt caacttcgga tcgagagatg
    47521 gttttaacag tcgcttcttc tgctagagat gctactattt gtttgccgta tcgttttccg
    47581 acgattctcc tatccaaaat aagagttaag gaacgttggt attcacgtct catacttctt
    47641 cccaaagcct gttttaaacg aataatggcc attggcaatt gataatcata aaaggcattt
    47701 ttcccttctt gattcagttc ttgattaatc tttttcgtca agggttcttg aggattttgg
    47761 aaaggaagcc tcggtacaac ttgaatcaca aaaggatggc ttgaaaaatc aactccctcc
    47821 cagaaacttg ctgcaccaag caagatttgt tgttcacctt tttcaaagcg tttctttagc
    47881 tgatgaacat ccccattttt atactgggcc aagtggctaa ctgtaagtaa atccgatact
    47941 gctagaagca tgtctttagc ggtaaagaga accaaaatcg gttgctggaa agcttgaatt
    48001 tccactagta aagcagctac ctctctggca tagacttcta aggaggtttc tgttaccaga
    48061 gggaaatctt tgaccataac cacttcttgt tcctgttttc cccgagattc aatcttgaca
    48121 aatttagctt caggatagcc taaaaggtct gccaaagaaa ccctctgact aatctcaaga
    48181 gtagccgata ctcccaggac ttggcaactc tcaggaagta aagaggacag aagagtacgg
    48241 cctgattttg tagaagaaat ctgaattttc ttttgactcg tttcagttac ttcaagccag
    48301 taatcacctt cagctgtaaa atagcgaacc agctcatcaa agccttctac ttctaattct
    48361 gaaaaatact gatggagatt gtccagagaa tctaagatat ttttcctaga tttaccagac
    48421 tgaaattgtt ctatcaagta gagacactca aagcgaatac tttctagtat ccgttgttga
    48481 accctgtttt cttctcctac taaagcctta tcaattaaat cgataataga ttgtatatcg
    48541 taggtctctt gaagcagatt ttctagagct aacaaaatct tttggacttc atcaataatc
    48601 agtaaacggt cactgacaaa ttcaggatta tcttcaagtc tggtcacgaa ataggcatga
    48661 ttagtcacta aaagcttgca agtctctgcc ctttcttgac tacgtttcca aaaatcttcc
    48721 gtcacaaata agctctggga tgataaattc ccatcatgac gaaggtctgc tagaaaatgt
    48781 tggtaacggt agagttgccc gatttcatcc aaatctcctg tctctgtctc agtaagccag
    48841 accaagactt gcattttaaa gcgtctaaat aagcgatttt catcattttc ctgcaaggaa
    48901 tgataaaagg catccaactt cagataattt tgtggtccct ttaagctatg aatatctgta
    48961 tggaacactt ccttgagacg tttaccttct tcttccatga tttgattttg aagaatcttt
    49021 gtcggaacac taagaacaat ttgtcgctct ttggattgag ataaagcggg taagagatag
    49081 ccataggttt tcccaatccc tgtcggcgct tgaatcagaa agacaggttc atctttcaat
    49141 agcaagccaa cctctttagc aaaactttct tgttcctccc tcacttcaag gttcaacaga
    49201 gaaatatttt tagaaaagtc ttgagatagt tttcgtagct ccagagaagc tgccgttttc
    49261 ttaaaataca gaccttgaac ttggaccaag tctggagaac tcaggataga ttggttgcga
    49321 taagtttcct caataaccag gtaggactca tataggagag cgtcagccat ttccagcaag
    49381 cgttccaaga gacctttagg aagctgggtc atcttttccc gtaaaaaaag aagtaattct
    49441 gctgtagctt gggcatctga aagggctgtg tgtgcgtgtt taagaggaat tcctaattct
    49501 cgacacaaaa tcggcaagct atatttttcc agttcaggga aaaagacctg ggccaattcg
    49561 accgtatcaa cacgagggtt tcttagctca tagccttcaa aaaataaatt ttccgccaag
    49621 agattagcat caaactgaac attatgggct acaaaaatcc catcctccac caagtcaaat
    49681 atttttctgg caacttgcga aaaatcaggt gcttgcgcca gacgttggtc tgtcaatcct
    49741 gtcagttctt tgatatgagc atccaagggt tcatgtggat tgacatccgt cgtatagtga
    49801 tcgacgattt ctccgtcctc aatcacgaca attcccactt ggataatttt agccttacta
    49861 cctgtgctag ttgcctctaa atccaccaca acatagcgat taccaatcgt tttcattata
    49921 aaaaattata ccaaaaaaag ggccatttgg cacctgcaaa cataggataa ttttcaaact
    49981 caagaacact acttttctta aaaatcccat cgaatagagc attctagcct gctgattttt
    50041 gtaaaatagt gaagaaatac gaaaaattga gagaagaaat gtttgcatct tccttctctc
    50101 aacgaatcat gtattttatc taaccatgtc aggatcgtag tcataaaatc ctgtatcaag
    50161 gaaacggttt ttagggtgaa gtttacgaac ttcttcatcc agcaagaagg cttgatcatg
    50221 gctaaagttg ccctcttgaa tcaaattacg cgcttggata aagagttttg caatctcaac
    50281 aaagttctga ccaggagtgt agagcccttc tagtttccag cgagtaaagc catgctccac
    50341 caattctgtt aatttgatca tcaaatcaag gtcattgttg gcaaagatat gggtcccatg
    50401 attatcttca aaaatggaat agtggctctc tggatcactt ggctcagcca agaagaggtc
    50461 acgtttatgc gtcttttcat catcgatatg tgtaaagtta tagtagtttt gcaagagtgg
    50521 acgtttagaa tgatggatga cgctagcacc gtaaaccaaa acttcagcag gaatttccaa
    50581 aatctctggc attttgaaaa gttcagctga tggaatttca cgcgccaaaa cagcctcaga
    50641 tgcgccagcc ttttgtcccc agaagttaat ctgacgactg ctagttacca tggttgaagc
    50701 atcgtagatg gtcttaaatg aataaccatc gcggttaact acgtaaaaga cgcctgcatc
    50761 cccaatcgta atatagtctg tcttgatttc ttccaagaag tctaagaaag gcttgatacg
    50821 gtccatcata tcttggtgca tgagagcatt gaccgcaacg agcaattcct taccagcatc
    50881 atgaaccaac ttagcgattt cacgtaattg gtcataacta aaggtcgttg gcagacgaag
    50941 gccaaaatct ttctcaccga catagatacg gtctacgcca gcttcgagta gttgttcaac
    51001 ttgttcaata ctttcagcag ttgctgtaat gacaatcttt tccataagaa aaattatacc
    51061 acatttctcc aaaatcatcc atgctttgaa aatgaaaagg gactttattc tttttgtaac
    51121 ctttctgtaa taattctctg ccgaaaaaat gataaaatag gtatgtactg ttaaggagag
    51181 aattatgccc gtaagaaaat tacaatccta tgaggtagac tatcaagaag aattaaacca
    51241 gcagcttcct cattaccaag cttatacacc tgaagcgcaa tctgatgcca atctcaagga
    51301 aatcctattt tttattaata tcgctgtttt ttgtatctgt attgctatct ttagttttat
    51361 ctttttagca ttaaaattat caactgctct tgcctttgcc gtagcaatcg gattcagctt
    51421 acttgtttta aaagttcaac ggtctattat caaacgaaaa cgtagaagat aaatccaaaa
    51481 tatcgcccca attggagcga tatttttatt ttttcttttt agatggtgtc tgaatggcaa
    51541 tcttcacttc aaagattgtt cccttgggtt tattatcttt gacagtaaca gttcctttta
    51601 gagcatctac aatttgcttg gctagggata atcctaaacc aaaaccacct ttttgccggg
    51661 ttctagcctt gtctactcga taaaaacggt caaaaatttt ctttttatct tctgtcgaaa
    51721 taccgattcc attatcagaa acaagtaaat aaagattgcg atcggtcgcc gagataagaa
    51781 aatcaatttc accatcctcc tcagtatact tgacggcatt atcgaaaaga atggtcatca
    51841 gttgtttcag aagaagctga tctgtgacaa ttgttcgatg gatacgattt tcaaaacgga
    51901 agacacgatt attttccgaa gcaatcatct catagtttgt gaaagttgta ttaaaaaagc
    51961 tagttggaac ttctgcaagc tccggcttaa tcccatcatc tctccgagct aagttcagca
    52021 agcttgtcgt taaaaaacgc atatttcgga cttcttccaa actcgatgca atgctttcgc
    52081 tcacatccat aatggtagct tctggcttac gaaaaagggt ctctaagcga ttttgcaaaa
    52141 ctgcgagtgg agttcgtaac tcatgactgg cattttccac aaaagactgt tgcttctgca
    52201 tactctcaag caggggccta acactgaccc tagctagata gagactggca agtaaagaca
    52261 aaatccagaa actagccatc acgaccacaa tcaattgctc atgcttttga ctagcctgct
    52321 ccaactgact ggtattaatc aagacagcag catacttgat attggttgaa accgaactaa
    52381 tattggtctc catcaaaatc acacgataga tttcttcctg cccatagcta ttaaaaacct
    52441 gaatctggta gatatgtcct agttctttct tttctaactt aatcttatcc aagcccaaaa
    52501 atcgatttcc agaaagaagt tgagtaaagt ctttatcaaa gagaatgact tccgtattgg
    52561 aactgacatt aggttttatt tctactttac tagcgtccgc cctagcattt tctaaatctt
    52621 taatctcttc tgttgcccta tttatagcca gctgaataac tgcttgagga ttttcactca
    52681 gtccatgaag cttatcgtcc accgaagtat aaagactcga atgcatgact tgtaaaataa
    52741 tcagagtcat tgtagaaaaa atcagggtga agacaccgaa gttgcggata aaataactaa
    52801 agtcatccgc ataccatgtt tttttaagtt tactgaacat cttttaaaag atacccaaca
    52861 ctacgcaaag tttgcaaatt ctctgcaaaa gtggttccct ttaatttctt acggactttt
    52921 gaaacataga cttcgacaac cgaaatcgtt gtatcactat caaatcccca tagacggtca
    52981 aaaatctgcg tcttaggcaa aatcacattt tgattttgaa ggaaataaac tagtaaatcg
    53041 aactctttcc ccagcaattc gacaggagta tcttcaactt taacggtatt ggttgataaa
    53101 ttaaccacga tattcccata agtcaaggtg ttttcattaa acttccctga acgtttaaga
    53161 agggcctgaa tccgcatttt aagttcttct aggtagaaag gtttggtcag ataatcatcc
    53221 gctcccagtt caaatccatg tcccttgtca tccaaacttt ccttggcagt cataatcaga
    53281 actggtgtcg taattccctt ttcacgcaat tcttttaaga cttggaaacc atttttttct
    53341 ggcaacatca aatccagcaa aatcaagtca tagacaccac tctcagcttc gtagagacct
    53401 tcttctccat caaatacctg cataacatcc gcaaaatcgt ctaaaaagtc aaatactgaa
    53461 tttgacagac ctaggtcatc ctcaaccaat aagattttta tcatgagaaa ctcctcctta
    53521 ttaaaactat tataccaaat ttgccttaaa aaaaactcaa ctctctgcat tttacatgag
    53581 atagctgagt tttcttttta ttttaggctt atttatgcat ttccgtattg aagaacaact
    53641 gcttcgactg cagctttttc acggctaatc aagtcaacac gtgctgcaat ttccttgatt
    53701 cccataccga tgttacggct aagagcaagg tcagaaagtt gcggctcaaa gaactccttg
    53761 tattccgcca agcgttgctg agtcttaaat acatgagcag gaaggataac aaagctatca
    53821 aagctcatat ctcctccaag ggctgcctta atccaagccc agttttcacg cgcccaagac
    53881 caagctgttt tctgagttgc ttgatgagct aggaattggt aataccaagc agacaagtcc
    53941 tgtggtttga ccacaaattt gtccttccaa gaagtaatca agttttggat attatccgca
    54001 tctgtactgt atgcaagagc tgctgccaac tggcgtttaa agacagcatc tgttgcgtga
    54061 gtataagtat caagataaag tgctaacaag tctttagtct catgatgttt catctcatta
    54121 atcagaactt gtgaacgaat agctgctggg agtcctgcaa gattctcctt gtgtgttgcg
    54181 aagatttggc tagcgacttg actagcttct gcatcatttg agcgaatcat catcgaaaca
    54241 gccagctgac gaaccaattc atcctcatct gattctccgt ctttagcttc aaaaccaaga
    54301 cggtcatagt tatgacgagc caatttagca accagtcctt tgaaggctgt ttcagcatcc
    54361 gttccttcat caataaagcg ctcaagggct gaaatcactt gagaaacagc tgaaaccacc
    54421 agataagact cttccttagc aagtttatca agaactggaa gcaagtctgc ataagaaatg
    54481 tgccctgcct cagccaacaa acgacgttct tgaacaattt gcagtttgct tgtgttatca
    54541 agtgtctcta gctcagcaag aacagcttct aacaagtctc cttgatagtc ggtaatatag
    54601 tgggcagtat tttcagtgtt gagacgaaga gctccttcat tttcagcaag aagagctgcg
    54661 tagccaggga tttcgatact ttcagtttcg agtgtatcag gcaagccttt ccagttgcta
    54721 ttgaggggca ccacccagag acggttcttg tcttcgttct caccgatgaa gaattgtttt
    54781 tgtgaaatct tcaagacatc attttcaact ttgacagtaa gaactgggta accaggctgt
    54841 tccaaccaag aatccatgaa ggctgcgaca tcacgtcctg acgcttgacc aagggcatcc
    54901 caaaggtcac taccaatggt gttgctgtat tggtgttttt caaagtaggc gtgcaaacct
    54961 ttagcaaaat cagcatctcc tagccaacgg cgaagcatgt gcatgagacg gcttcctttg
    55021 gcatagacga tagcgccgtc aaagagtgta ttgatttcat ctggatgttt aacttcgacg
    55081 tggacagact gaacgccatc agtagcgtca cgttcaagag caagaggtac tccacctgtt
    55141 tggaaatctt caaagatatt ccagcttggt tcgatggtat ccacacagac gtattccatc
    55201 atattagcga aactttcatt gagccaaagg tcatcccacc atttcatagt cacgaggttc
    55261 ccaaaccatt ggtgagccaa ttcatgggcc acaacaaggg caacttgttg acggctagca
    55321 aatgtagagt tctcatcgac aaccaagtaa acttcacggt aggtcacaag accccagttt
    55381 tccatagcac cagctgagaa gtcaggaagg gcgatgtgga gagattgagg aattgggtac
    55441 ttaactccat agtaatcttc gtaaaactcg atagagcgaa cagcgatatc cagtgagaaa
    55501 tcaagatttg aaagtggatg tgctttggtt gagtagacac ctaccagggt accattttta
    55561 gttttagcgg tcaccccttg caaatcacca gcaacaaagg ccaacaagta agaagacatg
    55621 cgaggtgttg tctcaaactt ccagatacct gtttccttac ggttttcaac atcgatttct
    55681 ggcatgtttg acaaggccaa ttcaccttct gcttggtcaa agcgaagaga gaggtcaaaa
    55741 gttgctttgg cttcaggctc atccacacac gggaaagctt cacgcgcaaa atggctctcg
    55801 aactgagtag acaagacctc cttcttgact ccatcaactg tataataaga agggtaaatc
    55861 cctgtcatgt tgtctgtaat tttaccagaa aaggcaagaa ccaattcaac ttgaccagcc
    55921 tcagccaatt cgatatgaag ggcttcattg tcatggtcaa ctgtaaatgg acgagcttga
    55981 cctgcaactt ctacagaggt gatttccaag tctttttggt ggagggagat gcggtcactc
    56041 tgtgcttgac cagtgatggt cactttccca gaaaaagtct tggtctcacg actcaaatct
    56101 aaaaataaat cataatgttc aggaacaaat tgcttaataa aatgttcaac tgcttgcata
    56161 gttttctcct attctaagtt taagagctgc tgctcttctt caaacaaact tattatatca
    56221 tattttgctt gagaaaaaag gattggacag cgatttccaa aactttcttc cttctaatag
    56281 tctacagtgg gtagaccttg cgaaattctt ctaaaacaac cttgctttca ggtgtaaaag
    56341 tcagccctac ttcacccaaa cagtctgtga aaaagtcctc atgaacctgg cgccaatagg
    56401 caagtgattt gtctccctca ccttccttaa aggcatgttg cgcagaaact tgattgaaga
    56461 gttcaacaga aacctttgta atttcgacaa tgcagacagc ctgattttga ctatctaaaa
    56521 tgacatcgaa ggtccctact tggggaagtg gttcgtcttc tagtacatag aggtcatagg
    56581 ctgatgctgt tgctgtcttt tctcctttaa acaccaaatc cgctaaaagg tctggttcaa
    56641 ctccaaaagc ccaagcatcg atttcatctc cgatcaaagg attgatttgc ttgtatttat
    56701 tccacatttc ttgcggtgtc atgggtactc ctttgtaatt ttttactttc ttcttttatg
    56761 tgtttaagat gatctggatg gtcaatctct aaatcaaaaa tctctggaat agaactgtag
    56821 tggataatgc acttgatacc caactgattc attttttgta tgaaagaagt attcagatag
    56881 cctgctacag caaaattaat cttgttcttt cttgctttat cctgcatatc tcttagcata
    56941 tctaacatta ttggactttc catatcatgc cattgactgt ttctcatagt cgcaaaaaca
    57001 aaggaagtca aatcattcat tccaactaca atctttgaaa tgcccgtttc cagtatacta
    57061 gataagtcaa aatacgctga cggtaattca atcatcgttc cgactttccc agtaaagcca
    57121 tactgacgca atactgtaat agcttgtttt aattggtcgg catcattgac aaaaggaaag
    57181 ataacagata gattggggtt ggtttgataa acttctgtaa tgacatgtgc ttcagcctga
    57241 aattcatcca aacacgccag taaacgccta gttcctctat agccaaacag aggataaatt
    57301 ttttcaagaa ttttttcgcc actaagggca agttgatttt tcatagccat tcacctcgtc
    57361 ttaaaagata caatatcata tataattata tcaaaatttc ctctagttca aaagcttcat
    57421 aaggttcaga taactcatat cctaaaaatt ctgctacttt tttggaagcc tcattatgag
    57481 catcccaaag tggaaacata tctctattta aactctctag aatcattgca gcaccaagct
    57541 ttttagcaaa tccatttcct tgttcgtttg gtctagttgc aacttccact tcaactgctt
    57601 tacggtaaac taaccctgag gaaatcccag caatcagttc attattttta agaatcacaa
    57661 agccaaatcc accttttaaa acaaaatcct gataggactc aaaatccccc tgtaaatcct
    57721 gtgaccattc ttccgtagaa aagcagttat aaatatgatt atcaataggc acaatattgt
    57781 aaccttcctc taaatgagta actagattat ttaaaaattc aacttgaaaa tttgccttat
    57841 ctttaaaaga atagcgagta aaagaattta gccccacttt tcgatgcaga aaatcttgcc
    57901 aattagtatt ttctgaaata ataatcttat aatctaaacc atattttcta acaaaatctt
    57961 cccaaaatct ggaatccaac tcccctgcta ggtatagaaa attcccaaca tcataaaagc
    58021 ttgttgtcct atcattgttt cggtagacag ttccaatttg agatttaaga ccatagagaa
    58081 ccatattttt cttccatgtt ttaaatagtt ccattatccc tctacttcac cttccaattc
    58141 atgtaagaag tcttgtccag ttctggaaat cctaataatt cagacttaac cttaaagact
    58201 aatggcgatg cattttcttc tgtaatctct tgaatatcca tccaaatata tccaagtgaa
    58261 tcattcgcac catcagacac agcttccgaa atcgtaactt gaggtgcact ctcattcatt
    58321 tcaacatcat acaaggccat gacatggtga accataaaat tttttaactc ttctctgacg
    58381 aaaacatcgt agattcgagg attagagtag cttctaacag taaatcccgt ctcttccata
    58441 acttctctag tcagcgtttc cgtcagtcct tcaccaagtt gctgactgcc tccaggtaga
    58501 tcataccgat gttgataagg acctctcgtt ttttcaatgc agagtaactt tccattttca
    58561 aagcaaacac agtagacccc aaagtgattt ttgatttcca tccaactcct cctacttcaa
    58621 agaccagcca ccatctattg tcagaatttg tccctgcatg gcagatgcct ttccactggc
    58681 caaaaagaga ctgacttctg ccacttcctc tggttcaatc cagcgcttga ttggtgtttc
    58741 actagccacc cagtcagcta agccacctgg ctcaaaatcc gcagcggtca tagctgtctt
    58801 gactgctcct ggagcgatac caaagacctg aatcccagct tcagcatagt ctagagccaa
    58861 ctgcttggtg aagccagcca aggcatgctt ggatgaagta taggcgtgac cacctccacc
    58921 tgctaggcta gaagcaatgg aacacatatt gatgatgatt ccctttttat tttccagcat
    58981 ttgtgtcaaa taataccgag tcaactctac tggaataatg tagttgattt caaaaatctc
    59041 ttgaatgtcc tgcgccgttt gttccaacag tggtttgtaa tcatccaaaa ctccagcagt
    59101 attacacaaa acatccacct gagggcacca gtcaaaaata ggttccaagt ccaaggtcaa
    59161 atctctctgt aaaaagcgaa aatcaccctc taagagtggc ttttcacctt ggtcaactcc
    59221 ataaacttga tagcccttct ctaaaaagag gcgagcttga gccaatccga tccctgaact
    59281 cactcctgta atgagtacac gtttagtcat gcacttctac ccaatccgtt gccaaaacat
    59341 cacaaactgt cgggctccac atggaaaaac cttctccttc gccagaaacg ttgattagga
    59401 aataaggtgt catttcaagt gcaagcccat tttgctcgat ggtatcaaag agttggacat
    59461 agttttccgc acctccccaa ccagttcgta catattttct cttagccttt aacccaggca
    59521 ggatctcttc aaatgtcatg tttttctcct ttaattctac attcttcatt taattatagc
    59581 aaaaaaccgc tttatacggc tttttaaatg tgagttattc aaacctgcta ctacttacgg
    59641 caaattattc cctgcagcaa gataaatttc ataccattct tttcttgtta agctaaagtt
    59701 tgccgctcgg ctaacttctc tcaagtgctt aggatttgtt gtacctacga ctgcctgcat
    59761 ttttgctgga taacgcaata tccaagaaat ggcaatagtt gaagaggtta ctccatattt
    59821 aatagctaaa cgatcaagta cttgatttaa agcttgaaat ttctcatttc caacaaaatt
    59881 ccctttaaaa tacccgaatt gtaagacaga ccatgcttga atgaccacat cgtgtaattg
    59941 gcaatattca aaaatgctgc catctcgcat agctgcttga ctatcttcca tattaacatg
    60001 aaaagctgat tcaaatcctg gagtaaaagc cgcactcaat tgtagctgat taacagctaa
    60061 cggctgcttg acatcttttt taagcaactc catcatcata ggattttgat tagaaactcc
    60121 aaaatctcga actttacctt gtttataaag gagattaaag gcttctgcta cttggtcaga
    60181 ttccatcaaa gcatctggtc gatgaaggag caagctatct agatgatcaa tcttcaatct
    60241 ttgcaaaata ccgtctactg attttataat atagtcctta gaaaaatcaa aataggtaaa
    60301 ttcttcaatg cgaatgccac atttggactg aatccacatc ttttctctta aatctggacg
    60361 attttttagg acaagaccta acagttcttc acaacgacca cgaccataaa tatcagccaa
    60421 gtcgaaggca ttgattccaa cagaaagtgc tgtttctaca agctcttcaa cttcttttac
    60481 agatttatct tttattctca tcattccgag aacaatttct gataattctt tgtcatcttg
    60541 accaagagtt atgtatctca tcaaattttt ctcctttaat ttctaacatt cttcccttca
    60601 ttataacaaa aaaccgcttt gcaacgactt tttgactata cttcactcca ttttatcttc
    60661 ttaaacccac ggaacaagac aaagattcca ataaagagga cagctaaagg aataactttt
    60721 gtaaggaaaa catttgaaat tcccatccac tcataataac ggagcagaga acccaccaca
    60781 agatgggcaa taatcatact gacaaatgga cgaaagaccg cttctttcca attccaaata
    60841 ccgataacta gcgaaatcgt aaagatagac aaactatccc agggagccgg aatataaaag
    60901 gctccttctt gtatgaagct tgccattcct acatatccta aaacaactag aagaactata
    60961 gtcccaacaa caatgtaagt gccaattttc attttaggag aatcttggac taaacttctt
    61021 cgtaaaattg tggccacaag tccaaatcca atcagaaaaa taagaagttg ccctaaaaat
    61081 gtgagcaaat tgactgttaa gagaggacct ttagaaaaat cacttagtag ttgataataa
    61141 cgtaataccg ccaggacaag aattggcgtc aaaagggact ctttgataga actgcgaggt
    61201 gctcccttga gaatctcttt cattattttt ttaggattct tacctagata atcctctgca
    61261 ctcatgccat ctcgttctgc ttctgagaaa tctagcatca tcaaatagat ctgctctctg
    61321 agatagtctt catcatagag aaatccagca agattaaaac tttcccacaa ctcctcaaaa
    61381 tacttttgat tctcctcaga aaactcatgt agcaaagcgc ttgtttcttc gtaatacttc
    61441 attttcttca tggtttaacc cccattctta atcccttcta ctttttgact caaatcgtcc
    61501 cattgttgcc aaaagactga gacacgctct tctccttctt tcattaatga aaaatacttc
    61561 cgatctggac catctggcga cgggcgcatg tcgcctctta tccattgatt tttttctaac
    61621 ttttgcaaca aaggataaat agttcctgga acgatagtat caaatccagc ctctcgcaaa
    61681 gtctgaacca actcataacc ataccgctct ttttgaccaa tcatatccaa gacacaacct
    61741 tcaagaacac cttttaatag ctgagtttct ttcatcactt ctcccttcta atctattttg
    61801 taatacctac tagtaacttc acctatagta tattacttct acactagttt gtaaagcata
    61861 atagttaata ctcttcgaaa atctcttcaa accacgtcag cgtcgcccta ccgtatgtat
    61921 ggtt
//
LOCUS       DAVHSI010000009        59778 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.009, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000009 DAVHSI010000000
VERSION     DAVHSI010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.009"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..357
                     /locus_tag="VVR21_000610"
     CDS             <1..357
                     /locus_tag="VVR21_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054534.1"
                     /translation="LLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            556..2130
                     /locus_tag="VVR21_000611"
     CDS             556..2130
                     /locus_tag="VVR21_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6054535.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            2394..3182
                     /gene="codY"
                     /locus_tag="VVR21_000612"
     CDS             2394..3182
                     /gene="codY"
                     /locus_tag="VVR21_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU6054536.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            3182..3757
                     /locus_tag="VVR21_000613"
     CDS             3182..3757
                     /locus_tag="VVR21_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6054537.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            3839..3924
                     /locus_tag="VVR21_000614"
     tRNA            3839..3924
                     /locus_tag="VVR21_000614"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3873..3875,aa:Leu,seq:aag)
     gene            4207..5337
                     /gene="ugpC"
                     /locus_tag="VVR21_000615"
     CDS             4207..5337
                     /gene="ugpC"
                     /locus_tag="VVR21_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU6054538.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(5484..5630)
                     /locus_tag="VVR21_000616"
     CDS             complement(5484..5630)
                     /locus_tag="VVR21_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054539.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            5838..6596
                     /locus_tag="VVR21_000617"
     CDS             5838..6596
                     /locus_tag="VVR21_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU6054540.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            6683..7195
                     /locus_tag="VVR21_000618"
     CDS             6683..7195
                     /locus_tag="VVR21_000618"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU6054541.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            7377..8321
                     /locus_tag="VVR21_000619"
     CDS             7377..8321
                     /locus_tag="VVR21_000619"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU6054542.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            8330..9007
                     /locus_tag="VVR21_000620"
     CDS             8330..9007
                     /locus_tag="VVR21_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU6054543.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRYEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            9105..9863
                     /locus_tag="VVR21_000621"
     CDS             9105..9863
                     /locus_tag="VVR21_000621"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU6054544.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            9901..11405
                     /gene="lytC"
                     /locus_tag="VVR21_000622"
                     /pseudo
     CDS             9901..11405
                     /gene="lytC"
                     /locus_tag="VVR21_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            11901..12419
                     /locus_tag="VVR21_000623"
     CDS             11901..12419
                     /locus_tag="VVR21_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU6054545.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            12549..13055
                     /locus_tag="VVR21_000624"
     CDS             12549..13055
                     /locus_tag="VVR21_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU6054546.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            13055..13225
                     /locus_tag="VVR21_000625"
     CDS             13055..13225
                     /locus_tag="VVR21_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054547.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            13257..14489
                     /gene="clpX"
                     /locus_tag="VVR21_000626"
     CDS             13257..14489
                     /gene="clpX"
                     /locus_tag="VVR21_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU6054548.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            14498..15085
                     /locus_tag="VVR21_000627"
     CDS             14498..15085
                     /locus_tag="VVR21_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU6054549.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            15096..15476
                     /locus_tag="VVR21_000628"
     CDS             15096..15476
                     /locus_tag="VVR21_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU6054550.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            15528..16418
                     /gene="rapZ"
                     /locus_tag="VVR21_000629"
     CDS             15528..16418
                     /gene="rapZ"
                     /locus_tag="VVR21_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU6054551.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKCLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            16415..17392
                     /locus_tag="VVR21_000630"
     CDS             16415..17392
                     /locus_tag="VVR21_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU6054552.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            17389..18300
                     /gene="whiA"
                     /locus_tag="VVR21_000631"
     CDS             17389..18300
                     /gene="whiA"
                     /locus_tag="VVR21_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU6054553.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFSLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(18334..19302)
                     /locus_tag="VVR21_000632"
     CDS             complement(18334..19302)
                     /locus_tag="VVR21_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6054554.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLAKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAIKYIDPEQKVQPKHSTSL"
     gene            19438..20295
                     /locus_tag="VVR21_000633"
     CDS             19438..20295
                     /locus_tag="VVR21_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU6054555.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            20282..21061
                     /locus_tag="VVR21_000634"
     CDS             20282..21061
                     /locus_tag="VVR21_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU6054556.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            21085..22437
                     /locus_tag="VVR21_000635"
     CDS             21085..22437
                     /locus_tag="VVR21_000635"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU6054557.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            22511..22885
                     /locus_tag="VVR21_000636"
     CDS             22511..22885
                     /locus_tag="VVR21_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU6054558.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            22887..23735
                     /locus_tag="VVR21_000637"
     CDS             22887..23735
                     /locus_tag="VVR21_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6054559.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGMIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGSGSIAL
                     GYIPVI"
     gene            24012..24779
                     /locus_tag="VVR21_000638"
     CDS             24012..24779
                     /locus_tag="VVR21_000638"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU6054560.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            24791..25975
                     /locus_tag="VVR21_000639"
     CDS             24791..25975
                     /locus_tag="VVR21_000639"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU6054561.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            25972..27843
                     /locus_tag="VVR21_000640"
     CDS             25972..27843
                     /locus_tag="VVR21_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6054562.1"
                     /translation="MSDFIVEKLTKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYECYEYLSEFDS"
     gene            complement(27986..29170)
                     /gene="mntE"
                     /locus_tag="VVR21_000641"
     CDS             complement(27986..29170)
                     /gene="mntE"
                     /locus_tag="VVR21_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU6054563.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            29474..32170
                     /locus_tag="VVR21_000642"
     CDS             29474..32170
                     /locus_tag="VVR21_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU6054564.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFTQRKLGFDKNAI"
     gene            32183..32974
                     /gene="yghU"
                     /locus_tag="VVR21_000643"
     CDS             32183..32974
                     /gene="yghU"
                     /locus_tag="VVR21_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU6054565.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQVGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            33090..33500
                     /locus_tag="VVR21_000644"
     CDS             33090..33500
                     /locus_tag="VVR21_000644"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6054566.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            33512..35107
                     /locus_tag="VVR21_000645"
     CDS             33512..35107
                     /locus_tag="VVR21_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054567.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLIKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            35274..35438
                     /locus_tag="VVR21_000646"
     CDS             35274..35438
                     /locus_tag="VVR21_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU6054568.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGIALV
                     LAAVWLGWPK"
     gene            35517..36245
                     /gene="yaaA"
                     /locus_tag="VVR21_000647"
     CDS             35517..36245
                     /gene="yaaA"
                     /locus_tag="VVR21_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU6054569.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(36296..37780)
                     /locus_tag="VVR21_000648"
     CDS             complement(36296..37780)
                     /locus_tag="VVR21_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6054570.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            37996..45141
                     /locus_tag="VVR21_000649"
     CDS             37996..45141
                     /locus_tag="VVR21_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6054571.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKNKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQITY
                     KVHRFGNETVLGLPISNRVTKEAKPRIMQIGVAKELIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAQGAKGEKGARGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTGAQGAKGEKGDQGERGLTGAQGA
                     KGEKGAQGERGLTGAQGAKGEKGDRGERGLTGAQGAKGEKGAQGERGLTGAQGAKGEK
                     GDQGERGLTGAQGEKGARGERGLTGAKGEKGAQGQAGRDGVTPTVTVKDNKNDGTHTI
                     TINDGRGNVTSTVVRDGFDGASPLVETQRNDADKTTTVIFYYDKNGNNELDASDKKLK
                     EVVIADGAKGEKGDKGEQGLQGRDGEQGPKGEDGKTPTVKVTDGQDGTHTITINDGKG
                     GITTTVVRDGFDGASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADG
                     KQGPKGDKGDNGKDGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDGKTPKV
                     KAERDDAKKQTTLTFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDGKEVLN
                     GKVDPTTEGKYGDTFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEKGDQGE
                     RGLTGSKGEKGDQGERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPK
                     GEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQ
                     SPTITATRSVQNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHT
                     LTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYV
                     KNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKD
                     VLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGADGAKGEKG
                     DRGERGLTGAQGAKGADGAAGRDGRDGRDGKDVLNGKVNPEANQGKDGDKYVNTETGD
                     VFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKDPVT
                     VNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTPGTDELLGSEM
                     IKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKSPT
                     VTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGAIGQDGQTPTITTQRGQD
                     GQSTVVTITTPGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRATDAAATPTRN
                     GIRVTVYDDVNDNGVYDGGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITVQ
                     NPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKTPK
                     VEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKAATATTTENPDGSHTVTITNPDGTKNE
                     FVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPTAKVVDNGD
                     GTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGADGKETTTTIFDGKS
                     PKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDGVSPTVTVENNNDGTHVVTIT
                     NPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVTKTVIKDGKDGRDGR
                     DGRDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVPAQPTPNVPTPEVPVQP
                     TPAVPTPEVPVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQSDYISVL
                     LGSGILLSLYVGRRKED"
     gene            complement(45378..45926)
                     /locus_tag="VVR21_000650"
     CDS             complement(45378..45926)
                     /locus_tag="VVR21_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6054572.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASARQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            46247..46735
                     /locus_tag="VVR21_000651"
     CDS             46247..46735
                     /locus_tag="VVR21_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU6054573.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            46732..47919
                     /locus_tag="VVR21_000652"
     CDS             46732..47919
                     /locus_tag="VVR21_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6054574.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            47912..48277
                     /locus_tag="VVR21_000653"
     CDS             47912..48277
                     /locus_tag="VVR21_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6054575.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            48293..49639
                     /gene="asnS"
                     /locus_tag="VVR21_000654"
     CDS             48293..49639
                     /gene="asnS"
                     /locus_tag="VVR21_000654"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU6054576.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPVAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            49792..50082
                     /locus_tag="VVR21_000655"
     CDS             49792..50082
                     /locus_tag="VVR21_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU6054577.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            50094..50564
                     /gene="ssbA"
                     /locus_tag="VVR21_000656"
     CDS             50094..50564
                     /gene="ssbA"
                     /locus_tag="VVR21_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU6054578.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            50596..50835
                     /locus_tag="VVR21_000657"
     CDS             50596..50835
                     /locus_tag="VVR21_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU6054579.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            51130..52530
                     /locus_tag="VVR21_000658"
     CDS             51130..52530
                     /locus_tag="VVR21_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU6054580.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            52532..52891
                     /locus_tag="VVR21_000659"
     CDS             52532..52891
                     /locus_tag="VVR21_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU6054581.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            52945..53694
                     /locus_tag="VVR21_000660"
     CDS             52945..53694
                     /locus_tag="VVR21_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU6054582.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            53684..53983
                     /locus_tag="VVR21_000661"
     CDS             53684..53983
                     /locus_tag="VVR21_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU6054583.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            54054..54989
                     /locus_tag="VVR21_000662"
     CDS             54054..54989
                     /locus_tag="VVR21_000662"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU6054584.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            55076..55588
                     /locus_tag="VVR21_000663"
     CDS             55076..55588
                     /locus_tag="VVR21_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU6054585.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            55613..56221
                     /locus_tag="VVR21_000664"
     CDS             55613..56221
                     /locus_tag="VVR21_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU6054586.1"
                     /translation="MFGELNRYLDQYEDVILREIKAQFPDIAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYVLKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            56322..56519
                     /locus_tag="VVR21_000665"
     CDS             56322..56519
                     /locus_tag="VVR21_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6054587.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     ENAKGAVEGAVEGLKNVFTKE"
     gene            complement(56562..58007)
                     /locus_tag="VVR21_000666"
     CDS             complement(56562..58007)
                     /locus_tag="VVR21_000666"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU6054588.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKILAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISQDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQNHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            58113..59735
                     /locus_tag="VVR21_000667"
     CDS             58113..59735
                     /locus_tag="VVR21_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6054589.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVSKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLAMSLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
BASE COUNT        18253 a        11055 c        13634 g        16836 t
ORIGIN      
        1 ttactgcttg tcaatctttt cttttctctc tcactttggc tctttacaga ttccgtttta
       61 tttgtagttg ctatgtctat tttgatgact tgctatggag ctggtttttc tttgattcca
      121 gcttatctca gtgatatttt tggaaccaag gaattggccg ctctgcatgg ttatatttta
      181 acagcttggg caatggctgg tttagcggga cctattttat tagcagagac ttataaaatg
      241 gctcattcgt acacacaaac cttgttcgtt tttctcattt tatacagtat cgccttggct
      301 ttgtcttatt atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt
      361 tctgtagaaa tggggctatc ttttgctctg gtcttgtgtt atactagata ggttgcaaag
      421 aaaacagtac ttttcttttg tggaaaagaa gcaacacgat tttatatcta gttatatgaa
      481 aatacgtcat aaaaagaaaa gtataaacta agccctatag ggtggcttcg caccaccttt
      541 agaaagaaga ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt gctagcagaa
      601 attgaaaaag ctggttttgt agaagctagt cctatccaag aacaaactat tcctttggcc
      661 cttgaaggca aggatgttat cggtcaagct cagactggta caggaaaaac tgcagccttt
      721 ggcttgccta cccttgaaaa aatccgtaca gaagaagcga ctatccaagc cttggtcatc
      781 gctccaactc gtgaactagc tgtccaaagt caagaagaac tcttccgctt tggtcgtagt
      841 aagggagtca aagtccgttc agtatatggc ggatcaagca ttgaaaaaca aattaaggct
      901 cttaaatctg gtgcccatat cgtggtggga actccaggtc gcctcttgga cttgattaaa
      961 cgcaaggcct tgaaattaca aaacattgaa acccttatcc ttgacgaagc ggatgaaatg
     1021 cttaacatgg gcttccttga agacatcgaa gccattattt cccgtgtacc tgagaaccgt
     1081 caaactttgc ttttctcagc aactatgcca gatgccatca aacgtatcgg tgttcagttt
     1141 atgaaagccc ctgaacatgt caagattgcg gctaaggaat tgacaacaga attggttgac
     1201 cagtactata tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg tctcatggat
     1261 gtggcacaac cagaactcgc tattgtattt ggtcgtacca aacgccgtgt ggatgaattg
     1321 actcgtggtt tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga cctagaccaa
     1381 aacaaacgtc ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt tttggttgcg
     1441 acagacgttg cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta caactacgat
     1501 attccacaag atcctgagag ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag
     1561 tcaggtcaat ctattacttt tgttgctcca aacgaaatgg gttaccttca aatcattgaa
     1621 aacttgacta agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa
     1681 tcaaaaaaac aggtggctct caagaaaatc gaacgtgatt ttgcagatga aaccattcgt
     1741 gccaactttg agaaatttgg taaggatgct cgcaaattgg ctgctgagtt tactccagaa
     1801 gaattggcaa tgtatatctt gagtctgaca gtccaagacc cagatagcct tccagaagtg
     1861 gagattgcac gtgaaaaacc actaccgttt aaaccatcag gtaatggttt cggtggtaaa
     1921 gctaagggag gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga tcgccgtggc
     1981 aatggtcgcc gtgatgagtt caaaaaagga agtcgtggca acgatcgttt tgataaggaa
     2041 aaacgttacc gtaaggataa taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc
     2101 tttgttattc gtaacaaagg cgataaataa gaaaaagcgg ttcaaaatga atcgcttttt
     2161 tatataagga gaccgaatgt gaaaagacaa ataaaattac tatattatct tttataatgt
     2221 tatgatacac aaaaataggc aacttgtcaa tagaaaagga acaatttaat taaaaatatt
     2281 ctggttttta attaaattgt aagtcaatgc aagtcaataa ggaattttca gataattatt
     2341 gaaaaagaga cgtttttatg ttataatgat agcgattaaa ttcgaggtga aaaatggcac
     2401 atttattaga aaaaactaga aaaattacat caattttgaa acgctcagag gagcagttgc
     2461 aggatgagct cccttacaac gctattacgc gtcagttagc ggatattatt cattgcaatg
     2521 cctgcattat caatagtaag ggacgtctgc ttggctattt tatgcgttat aaaacaaata
     2581 cagatcgcgt agagcaattc ttccaaacta agattttccc agatgactac gttcaagggg
     2641 ctaatatgat ttacgaaaca gaagcaaact tgcctgttga gcatgatatg agtattttcc
     2701 ctgttgagag tagagatgat tttccagatg gcttgacgac tattgcaccg attcatgtat
     2761 cggggattcg ccttggttct ttgattattt ggcgtaatga taaaaaattc gaagatgagg
     2821 acttggttct tgttgagatt gccagtaccg ttgttgggat tcagcttctt aacttccaac
     2881 gtgaagaaga tgagaaaaat attcgtcgtc gtactgctgt caccatggcg gtcaataccc
     2941 tttcttactc cgaactccgt gctgtttcag caattttagg ggaattaaat ggaaatgaag
     3001 ggaagttgac tgcgtcagtg attgcagatc gtatcggaat cactcgctct gtgattgtca
     3061 atgctcttcg taaacttgag tctgcgggga ttattgaaag tcgctcactt ggaatgaagg
     3121 gaacctatct taaggtcttg atttcagata tttttgaaga agtgaagaaa agagattact
     3181 aatgacaaag gctttaattt cgattgatta tacagaagat tttgttgctg atagtgggaa
     3241 gctgacagca ggtgctccag ctcaggcgat ttcggatgcc atcagcaagg taactcgatt
     3301 agcttttgaa cgaggagatt atatcttctt tactattgat gctcatgaag aaaacgattt
     3361 tttccatccg gaaagtaagt tatttcctcc tcataatctg attgggacga gtggacggaa
     3421 tttatatgga gatttgggga tcttttatca agagcatggt tcagacagtc gtgtcttttg
     3481 gatggataaa cgccattact cagctttttc agggactgac ctagatattc gtttgagaga
     3541 gcgtagagtg tctaccgtta tcttaacagg tgtcttgacg gatatctgtg tcctacatac
     3601 agctatagat gcctataatc taggatatga catcgagatt gttaaaccag ctgttgcttc
     3661 tatctggcct gaaaatcatc aatttgccct aggtcatttc aaaaatacac tcggagctaa
     3721 gttagtagat gaaaatctaa atgaactttc tgagtaacct ggttggtgaa aatgaaaaaa
     3781 tttgaaaaaa agtgttgaca agcatcccaa aagttgatat actagtaaag taatcgatgc
     3841 ggggatggcg gaattggcag acgcgcagga ctaaggatcc tgtgaccgct ttaggtcgtg
     3901 agggttcaag tccctctctc cgcataggaa aagagttagc taaagctagc tcttttgtat
     3961 ttctctaaaa aattagaatc cagtcaaatg tagtggagaa tcagcgaaaa tatgggaaaa
     4021 ctgatccttg tttctgcttt tgtcatagaa gaataataaa gattatcttc ttcaaattct
     4081 ccgatattct ctaaagtttt gtgcaagttg cacagaactt ttttattttt ttggtcatct
     4141 tgccatagaa atataaagcg ttttcatcta taatataatt atcaaaagac aaaaggagtt
     4201 cacctcatgg tagaattgaa tcttaaaaat atttacaaaa aatatccaaa cagcgaacac
     4261 tattcagttg aagatttcaa cttgaacatc aaagataaag aatttatcgt tttcgtagga
     4321 ccttcaggat gtggtaaatc aactacactc cgtatgattg ctggtcttga agacatcaca
     4381 gaaggtactg catctatcga tggcgtggtt gtcaacgacg tagctccaaa agaccgtgat
     4441 atcgccatgg tattccaaaa ctacgctctt tacccacaca tgactgttta tgacaacatg
     4501 gctttcggtt tgaaattgcg taaatacagc aaagaagaca ttaacaaacg tgttcaagaa
     4561 gcagctgaaa tacttggatt gaaagaattc ttggaacgta aaccagctga cctttcaggt
     4621 ggtcaacgtc aacgtgttgc catggggcgt gcgattgtcc gtgatgcgaa agtattcttg
     4681 atggacgaac ctttgtcaaa cttggatgcc aaacttcgtg tatcaatgcg tgctgaaatc
     4741 gctaaaattc accgtcgtat cggagctaca actatctatg taactcacga ccaaacagaa
     4801 gcgatgacac ttgcagaccg tatcgttatt atgtcagcta ctaagaaccc tgctggtaca
     4861 ggtactatcg gacgtgtaga acaaatcggt actcctcaag aagtttacaa aaatccagtt
     4921 aacaaatttg ttgcaggatt catcggaagc ccagctatga atttcatcaa cgtgaaattg
     4981 gttggtagcg aaattgtttc tgacggtttc cgtttgaaag tgccagaagg agcattgaaa
     5041 gttcttcgtg aaaaaggcta cgaaggaaaa gaattgatct ttggtatccg tccagaagac
     5101 gtgaatgcag aacctgcttt ccttgaaaca ttcccagact gtgttgtaaa agcgactatc
     5161 tctgtatcag aactgcttgg ttcagaatct cacctttact gccaagttgg taaagacgag
     5221 tttgttgcaa aagttgatgc tcgtgactac ttgcaaacag gtgcaacagt tgagcttgga
     5281 tttgacttga acaaagcaca cttcttcgat gtagaaactg aaaaaacaat ttactaaaat
     5341 aaataaaatt caaaacacta caagaaaaga tatctcttta tcaattgtag tggagagata
     5401 tcagttaatc tagggagaga aacaaaatgc ttctctcctt tttgctaggg aagtcatatt
     5461 atgcatctat attgtgatgc tctttaatac tcttcgaaaa tctcttcaaa ccacgtcaac
     5521 gtcgccttgc cgtacgtatg attactgatt tcgtcagttt tatctgcaac ctcaaagatg
     5581 tactttgagc agcttacggc tagtttccta gtttgctctt tgatttccat tgagtattat
     5641 ttgtgggtac catctacaag tgaagctata tgcgtaaact acgtgagcaa ttgaattcga
     5701 actagagagg taataataaa tttatgctat agttatggtg acttgtatgc ttttgattct
     5761 agtttatcaa ataatagatt agaattgtca gataatatca ttttgtgtta taatgaagaa
     5821 aaaacagagg tgtgcaaatg tcagaagcag gtcataagtt tttagcaaaa ttggggaaaa
     5881 aacgcttacg tccaggtgga aagcgtgcca cagattggtt aattgcagaa ggaggatttt
     5941 caaaagaaaa gagaatacta gaggttgcgt gtaatagggg aactacagca attgagttgg
     6001 cacagcgttt tggttgcaag ataactgctg ttgatatgga tgctcaagct ttagaagtgg
     6061 ctaaaaaatc tgctggaacg gcaggtgttg ctcatttaat cagttttgaa agagcaaatg
     6121 caatgaaact tccttatcaa gatgctagtt ttgatattgt tataaatgaa gctatgctga
     6181 ctatgcaagc cgatcaagct aagaaaaaat gtgtaatgga atatctaagg gtattaaaac
     6241 ctggaggtct tctcttgaca catgatgtac ttcttaagga agctaaagag tctatcagac
     6301 aggaattatc acaagcaatt catgtaaatg taggtccttt aactcaagat ggttgggaac
     6361 aggtgatgat agaatcaggt tattgtgatg tgaaagcatt gactggtgaa atgacattaa
     6421 tgaaattatc gggtatgatt tatgacgaag gtttgctagg aactttgaaa atttgtgtaa
     6481 atgcttgtaa aaaggagaat agaaagcagt ttttaactat gtataaaatg tttgctaaga
     6541 ataaacagaa attgggcttt attgcgatgg ctagttataa atcgtcaaaa cgttagataa
     6601 ttattgaagt taacttttcc ttttttcttt cttaaaaaat atgctataat agagagtaaa
     6661 aaactttgaa agaaagaaaa agatgaattt aaaagattac attgcaacaa ttgaaaatta
     6721 tccaaaggaa ggcattacct tccgtgatat tagtcctttg atggctgatg gaaatgctta
     6781 tagctacgct gttcgtgaaa tcgttcagta tgctactgac aagaaagtcg acatgatcgt
     6841 gggacctgaa gctcgtggat ttatcgtggg ttgtccagtt gcctttgagt tgggaattgg
     6901 ttttgcgcct gttcgtaagc caggtaaatt gccacgcgaa gttatttctg ctgactatga
     6961 aaaagagtac ggtgtcgata ccttgactat gcacgcggat gccattaagc caggtcaacg
     7021 tgttcttatt gtagatgacc ttttggcgac aggtggaact gttaaggcaa ctatcgagat
     7081 gattgaaaaa cttggtggtg ttatggcagg ttgtgccttc cttgttgaat tggatgaatt
     7141 gaacggccgt gaaaaaattg gtgactacga ctacaaagtt cttatgcatt attaatgaaa
     7201 acagtcccta gggctgtttt ctctacacta ggatataaaa atagactata actagttaga
     7261 gaaaaactat aattgaaaac tatatcttct tacagtataa taaaaggact aagtgtttga
     7321 gatttgtctt caaacatatg caattattcc tgaaagagta cagttaggag agggttatgc
     7381 cgattcgaat tgataaaaaa ttgccagctg ttgagatttt acggacagag aatatctttg
     7441 tcatggatga tcaacgtgct gcccaccaag atatccgtcc tttgaagatt ttaattttaa
     7501 atctcatgcc acagaaaatg gtcacagaga cccagttgtt gcgccacttg gctaatacac
     7561 ccctacaact ggatattgat tttctctata tggagagcca ccgttctaaa acaactcgtt
     7621 cagagcacat ggagaccttc tataaaactt ttcctgaagt caaggatgag tattttgatg
     7681 ggatgatcat cacgggtgct ccagttgagc atttaccatt tgaggaagtg gactattggg
     7741 aggaatttag acagatgctt gagtggtcta agactcatgt ctattcgacc cttcatatct
     7801 gttggggggc tcaggctggg ctttatctgc gctatggtgt agaaaaatac cagatggaca
     7861 gtaagctatc aggtatttat cctcaggaca ccctaaaaga gggtcacctt ctatttagag
     7921 gctttgatga tagctatgta tcccctcatt cacggcacac ggagatttct aaggaagagg
     7981 tcttaaacaa gaccaatctc gagattttat cagaaggacc tcaggttggg gtttctattt
     8041 tggccagtcg tgatttacga gaaatttata gttttggtca tttggagtat gaccgtgata
     8101 ccttggcaaa agagtatttt cgagatcgtg atgcaggttt cgacccacat attccagaaa
     8161 attactttaa agatgatgat gttaatcagg taccttgtct ttgttggtct tcatctgcag
     8221 ccctcttttt cagtaattgg gtaaaccatg cggtctatca ggagacgcct tttgattgga
     8281 gaaagataga agatgatgca tctgcatatg ggtatttata agaggaatta tgacatattt
     8341 agacgctttt aaatcaggta ccttggtttt accgagtgcc ctgctcttgc attttaagga
     8401 actctttcct tctagcgacg attttctggt ttggcaattt ttctatttgc aaaatacgac
     8461 aggcttagaa gaaatgtcgc caagccagat tgctgaaagg attggcaagg aaatttcgga
     8521 tgtcaaccag tccatttcta atctgacgga aaggggactg ctccagtatc gtactatcga
     8581 attaaatggc gaaattgaat tgctctttga tgctagtttg gccttggaac gtttggatga
     8641 cctgtttgga gcagttcgtt caagttcaga ccagctaaca cctcaaaacc agctcaagga
     8701 tttggtggaa accttccagc aggagttggg acgattgttg acgccttttg agattgagga
     8761 tttgaccaag acactaaagg aagatggaac cagtgctgac ttgattaagg aggctcttcg
     8821 tgaagctgtt ttgaatggaa aaccaaactg gaagtacatt caggcgattt tgagaaactg
     8881 gcgctatgaa ggaatcaaga gtgtggctca aattgaggcc aagagagcag aaagagaagc
     8941 aagcaatcct cagttgacac aggtatctgc agatttcata aatgccatgg atctctggaa
     9001 ggattaatcc atgcaagtag gcttgaaatc cgagtaagat ttgcaagctg tgtataattg
     9061 tgatagaata aatagaaaat aaattgaaaa aagaggtatg tgaaatgtca cgtaaaccat
     9121 ttatcgctgg taactggaaa atgaacaaaa atccagaaga agctaaagca ttcgttgaag
     9181 cagttgcatc aaaacttcct tcatcagatc ttgttgaagc aggtatcgct gctccagctc
     9241 ttgatttgac aactgttctt gctgttgcaa aaggctcaaa ccttaaagtt gctgctcaaa
     9301 actgctactt tgaaaatgca ggtgctttca ctggtgaaac tagcccacaa gttttgaaag
     9361 aaatcggtac tgactacgtt gttatcggtc actcagaacg ccgtgactac ttccatgaaa
     9421 ctgatgaaga tatcaacaaa aaagcaaaag caatctttgc gaacggtatg cttccaatca
     9481 tctgttgtgg tgaatcactt gaaacttacg aagctggtaa agctgctgaa ttcgtaggtg
     9541 ctcaagtatc tgctgcattg gctggattga ctgctgaaca agttgctgcc tcagttatcg
     9601 cttatgagcc aatctgggct atcggtactg gtaaatcagc ttcacaagac gatgcacaaa
     9661 aaatgtgtaa agttgttcgt gacgttgtag ctgctgactt tggtcaagaa gtcgcagaca
     9721 aagttcgtgt tcaatacggt ggttctgtta aacctgaaaa tgttgcttca tacatggctt
     9781 gcccagacgt tgacggtgcc cttgtaggtg gtgcgtcact tgaagctgaa agcttcttgg
     9841 ctttgcttga ctttgtaaaa taatcagtaa gtagcaaaag ctaggtggaa cagcattcag
     9901 atgtctgtta cattttttat aggagagaaa gattgaaaac aaaaattgga ttagcaagta
     9961 tctgtttact aggcttggca actagtcatg tcgctgcaaa tgaaactgaa gtagcaaaaa
    10021 cttcgcagga tacaacgaca gcttcaagta gttcagagca aaatcagtct tctaataaaa
    10081 cgcaaacgag cgcagaagta cagactaatg ctgctgccca ctgggatggg gattattatg
    10141 taaaggatga tggttctaaa gctcaaagtg aatggatttt tgacaactac tataaggctt
    10201 ggttttatat taattcagat ggtcgttact cgcagaatga atggcatgga aattactacc
    10261 tgaaatcagg tggatatatg gcccaaaacg agtggatcta tgacagtaat tacaagagtt
    10321 ggttttatct caagtcagat ggggcttatg ctcatcaaga atggcaattg attggaaata
    10381 agtggtacta cttcaagaag tggggttaca tggctaaaag ccaatggcaa ggaagttatt
    10441 tcttgaatgg tcaaggagct atgatgcaaa atgaatggct ctatgatcca gcctattctg
    10501 cttattttta tctaaaatcc gatggaactt atgctaacca agagtggcaa aaagtgggcg
    10561 gcaaatggta ctatttcaag aagtggggct atatggctcg gaatgagtgg caaggcaact
    10621 actatttgac tggaagtggt gccatggcga ctgacgaagt gattatggat ggtactcgct
    10681 atatctttgc ggcctctggt gagctcaaag aaaagaaaga tttgaatgtc ggctgggttc
    10741 acagagatgg taagcgctat ttctttaata atagagaaga acaagtggga accgaacatg
    10801 ctaagaaagt cattgatatt agtgagcaca atggtcgtat caatgattgg aaaaaggtta
    10861 ttgatgagaa cgaagtggat ggtgtcattg ttcgtctagg ttatagcggt aaagaagaca
    10921 aggaattggc gcataacatt aaggagttaa accgtctggg aattccttat ggtgtctatc
    10981 tctataccta tgctgaaaat gagaccgatg ctgagagtga cgctaaacag accattgaac
    11041 ttataaagaa atacaatatg aacctgtctt accctatcta ttatgatgtt gagaattggg
    11101 aatatgtaaa taagagtaag agagctccaa gtgatacagg cacttgggtt aaaatcatca
    11161 acaagtacat ggacacgatg aagcaggcgg gttatcaaaa tgtgtatgtc tatagctatc
    11221 gtagtttatt acagacgcgt ttaaaacacc cagatatttt aaaacatgta aactgggtag
    11281 cggcctatac gaatgcttta gaatgggaaa accctcatta ttcaggaaaa aaaggttggc
    11341 aatatacctc ttctgaatac atgaaaggaa tccaagggcg cgtagatgtc agcgtttggt
    11401 attaagcgat gatttgaaag agggatgtga tagtagcacc ctctttttct ttgttttatg
    11461 atagttcatc ctcgagtaaa ttcaagatct tgctcggaaa tgaagcttat atagtagatt
    11521 gaatatagac aaataccttg tgattggtaa aacattttag aaattcattt acctttccta
    11581 atcgacttgg tttcatctta tttcaatcta ttatagtatt ggggaatttc ttcaaaccac
    11641 atcagcttgg tcagttctac ctgcgacctc aaaacttgtg ctttggtcaa gctgggttta
    11701 gtttcctagt ttgctgatgg atttccattg actataagca tccaaccctc tttttgtctt
    11761 ctaaagaatt cttaaattat cagtctattg caacttttct catataagtt ctttgtcttg
    11821 ctattggttt tccttagtag tatactaagg tagtaatcat taagaagtgg ttacaaaaaa
    11881 taatgaatga ggtaaagaaa atggtagaat tgaaaaaaga agcagtaaaa gacgtaacat
    11941 cattgacaaa agcagcgcca gtagcattgg caaaaacaaa ggaagtcttg aaccaagctg
    12001 ttgctgattt gtatgtagct cacgttgctt tgcaccaagt gcactggtat atgcatggtc
    12061 gtggtttcct tgtatggcat ccaaaaatgg atgagtacat ggaagctctt gacggtcaat
    12121 tggatgaaat cagcgaacgc ttgattacac tcggtggaag cccattctct acattgacag
    12181 agttccttca aaatagtgaa atcgaagaag aagctggtga ataccgtaat gttgaagaaa
    12241 gcttggaacg tgttcttgtt atctaccgtt acttgtcaga acttttccaa aaaggtttgg
    12301 atgtcactga tgaagaaggt gacgatgtaa caaacggtat ctttgcaggc gctaaaactg
    12361 aaacagataa aacaatttgg atgcttgcag ccgaacttgg acaagcacct ggtttgtaag
    12421 aaataaggaa acatagataa atctgtagga aatttcttac agattttttc tattttgtaa
    12481 gctattccaa accagtcttt ttttgagttt tttgataaaa tagtactatc agtgaaaagg
    12541 atggaagcat gactaagaaa atcgtagcta tttgggccca ggatgaagag ggtgtgattg
    12601 gtaaggaaaa tcgtctgcct tggcatttgc cagcagaatt gcagcacttt aaagaaacaa
    12661 ctctgaatca tgctatcttg atggggcgtg tgacctttga tgggatgggg cgtcgcttgc
    12721 ttccaaaacg ggaaaccttg attttgacgc gtaatccgga agaaaagata gatggggttg
    12781 ctacttttca ggacgtccag tctgttcttg actggtatca ggctcaagaa aagaatctct
    12841 acattatcgg tgggaagcaa atttttcagg cttttgaagc ttaccttgat gaagtgattg
    12901 tcactcacat tcatgctcgg gtggaaggag atacctattt ccctgaagag cttgacttgt
    12961 ctctttttga gacagtttca agcaaatttt acgccaaaga tgagaagaat ccttatgatt
    13021 ttaccatcca ataccgcaag agaaaggaag tttaatggaa cggagtttat ttggtctatt
    13081 cacggctttt ctgtgtttca tctgctttct ggcaggagca caagcttttc gtaaaaagcg
    13141 ttacgggctt tctatcctcc tttggttaaa tgcctttacc aatctggtca atagtattca
    13201 tgctttttac atgaccttat tttagataga atgacagtat agaatggaag gaaatcatgt
    13261 ctacaaatag aaaaaatgat atgatggttt attgctcatt ttgtggcaaa aaccaagaag
    13321 aagtacaaaa aataattgct ggcaacaatg cttttatttg taatgaatgc gtggagttag
    13381 ctcaggaaat cattcgagaa gaattggttg aggaagtctt ggcagacttg tctgaggtgc
    13441 caaaaccaat tgaactcctc catatcttga accactatgt aattggtcaa gatcgtgcca
    13501 agcgtgcctt ggcagtggcg gtttataacc actacaaacg catcaatttc cacgatacac
    13561 gcgaagagtc agaagatgtg gatttgcaga agtcaaacat tttgatgatt ggcccaactg
    13621 gttcagggaa aactttcctt gcccagacct tggctaagag cttgaatgta ccttttgcta
    13681 ttgcggatgc gacagctctg acggaggctg gttatgtggg tgaggatgtg gaaaatatac
    13741 tcctcaaact cttgcaggtt gctgacttta acatcgaacg tgcagagcgt ggcattatct
    13801 atgtggatga aattgacaag attgccaaga agagtgagaa tgtgtctatc acacgtgatg
    13861 tttctggtga aggggtgcaa caagcccttc tcaagattat cgagggaact gttgctagcg
    13921 taccgcctca aggtggacgc aaacatccac aacaagagat gattcaagtg gatacaaaaa
    13981 atatcctctt catcgtgggt ggtgcttttg atggtattga agaaattgtc aaacaacgtc
    14041 tgggtgaaaa agtcatcgga tttggtcaaa acaataaggc gattgacgaa aacagctcat
    14101 acatgcaaga aatcatcgct gaagacattc aaaaatttgg tattatccct gagttgattg
    14161 gacgcttgcc tgtttttgcg gctcttgagc aattgaccgt tgatgacttg gttcgcatct
    14221 tgaaagagcc aagaaatgcc ttggtgaaac aataccaaac cttgctttct tatgatgatg
    14281 ttgagttgga atttgacgac gaagcccttc aagagattgc taataaagca atcgaacgga
    14341 agacaggggc gcgtggactt cgctccatta tcgaagaaac catgctagat gttatgtttg
    14401 aggtgccgag tcaggaaaat gtgaaattgg ttcgcatcac taaagaaact gtcgatggaa
    14461 cggataaacc gatcctagaa acagcctaga ggtgactatg gaacttaata cacacaatgc
    14521 tgaaatcttg ctcagtgcag ctaataagtc ccactatccg caggatgaac tgccagagat
    14581 tgccctagca gggcgttcaa atgttggtaa atccagcttt atcaacacta tgttgaaccg
    14641 taagaatctc gcccgtacat caggaaaacc tggtaaaacc cagctcctga acttttttaa
    14701 cattgatgac aagatgcgct ttgtggatgt gcctggttat ggctatgccc gtgtttctaa
    14761 aaaggaacgt gaaaagtggg ggtgcatgat tgaggagtac ttaacgactc gggaaaatct
    14821 ccgtgcggtt gtcagtctag ttgaccttcg tcatgacccg tcagcagatg atgtgcagat
    14881 gtacgaattt ctcaagtatt atgagattcc agtcatcatt gtggcgacca aggcggacaa
    14941 gattcctcgt ggtaaatgga acaagcatga atcagcaatc aaaaagaaat taaactttga
    15001 cccaagtgac gatttcatcc tcttttcatc tgtcagcaag gcagggatgg atgaggcttg
    15061 ggatgcaatc ttagaaaaat tgtgaggaaa agaaaatggc aaaaacaatt catacagata
    15121 aggccccaaa ggctatcgga ccctatgttc aaggaaaaat cgttggcaac cttttgtttg
    15181 ctagcggtca agttccccta tcccctgaaa ctggggaaat tgtaggagag aatatccaag
    15241 aacagacaga gcaagtcttg aaaaacatcg gtgctatttt ggcagaagca ggaacagact
    15301 ttgaccatgt tgtcaaaaca acttgtttct tgagcgatat gaacgacttt gttcctttta
    15361 atgaggttta ccaaacggcc ttcaaagagg aattcccagc tcgttcagct gtggaggtag
    15421 ctcgtcttcc tcgtgatgta aaagtcgaaa ttgaagtcat cgcagagatt ggataagcta
    15481 gttgaagttt ggtgttgcca aacttctttt gatataagga gaaaaagatg acaaagaaac
    15541 aacttcactt ggtgattgtg acagggatga gtggcgcagg gaaaactgta gccattcagt
    15601 ccttcgagga tctaggttat ttcaccattg ataatatgcc gccagctctc ttgcctaagt
    15661 ttttgcagct ggttgaaatt aaggaagaca atcctaagtt ggccttggta gtggatatgc
    15721 gtagccgttc tttcttttca gagattcaag ctgttttgga tgagttggaa aatcaagatg
    15781 gtttggattt caaaatcctc tttttggatg cggctgataa ggaattggtc gctcgttaca
    15841 aggaaaccag acggagtcac ccactagcag cagacggtcg tattttagat ggaatcaagt
    15901 tggaacgtga actcttggca cctttgaaaa atatgagcca aaatgtggtg gatacgactg
    15961 aactcactcc acgtgagctg cgcaaaaccc ttgcagagca gttttcagac caagaacaag
    16021 ctcagtcttt ccgtatcgaa gtcatgtctt tcggatttaa gtatggaatc ccgattgatg
    16081 cggacttggt ctttgatgtc cgtttcttgc caaatcccta ttatttacca gaactgagaa
    16141 accaaacggg tgtggatgaa cctgtttatg attatgtcat gaaccatcct gagtcagaag
    16201 acttttatca acatttattg gccttgattg agccgattct gccaagttac caaaaggaag
    16261 gtaagtccgt tttgaccatt gccatgggat gtacgggtgg acaacaccgt agtgtggcat
    16321 ttgctaaatg cttggcgcag gacttatcca agaattggtc tgttaatgaa gggcatcgcg
    16381 acaaagaccg cagaaaggaa acggtaaacc gttcatgaga aaaccaaaga taacggtgat
    16441 tggtggaggg actggaattc ccgtcattct aaaaagtctg cgggaaaaag atgtggaaat
    16501 cgcagctatc gtgacggtgg cagatgatgg tggttcttca ggtgaactcc gaaaaaatat
    16561 gcaacagttg acaccgccag gtgatcttcg taatgtcctt gtggccatgt cggatatgcc
    16621 taagttttat gagaaggtct ttcagtatcg gttctctgag gatgccggag cctttgctgg
    16681 ccatccattg ggaaatctca tcattgctgg cttgtcagaa atgcagggtt caacctataa
    16741 tgccatgcag ttattgagca aatttttcca tacaacaggg aaaatttatc cttccagtga
    16801 ccatcctttg acccttcatg cagtctttca ggatgggaca gaagtggttg gagagagtca
    16861 tattgtagac catcgaggca taattgacaa tgtctatgtg accaatgccc taaacgatga
    16921 tacgcctctg gccagccgtc gagtagtgca gaccatcctt gaaagtgaca tgattgtcct
    16981 agggccaggt tccctcttta cctctatttt gcccaatatc gtgattaagg aaattgggcg
    17041 ggctcttttg gaaaccaagg cagaaattgc ctatgtctgc aatatcatga cccaacgtgg
    17101 ggagacggaa cactttacag atagcgacca cgtggaagtc ttgcatcgtc accttggtcg
    17161 cccttttatc gacactgtct tggtgaatat tgaaaaagtg cctcaggaat acatgaattc
    17221 caaccgtttt gatgaatact tggtgcaagt ggaacacgat tttgtaggtc tttgtaagca
    17281 agtttcgcgc gtgatttcat ctaacttcct tcgtctggaa aatggcggtg ccttccacga
    17341 tggagatttg attgtggacg agttgatgcg cattatacag gtgaaaaaat gagtttcaca
    17401 gtagcagtaa aagaagaaat cctgggccaa caccatctga gctggcatga attatctgcc
    17461 attatcaaaa tgtctggtag catcggtctc tcgacttcgg gcttgacttt gtcagttgtg
    17521 acagaaaatg ccaaactggc ccgtcacctc tatgagtcct ttctccattt ctatgaaatc
    17581 aaatctgaaa ttcgtcacca ccaacggagc aatcttcgca agaatcgcgt ctataccgtt
    17641 tttacagatg aaaaggtgca ggatttgtta agtgatttgc acttggcaga ctctttcttt
    17701 agcctggaaa caggtattga tgaggcgatt ttatcggatg aggaagcagg tcgtgcctat
    17761 ctctgtggcg ctttcttggc aaatgggagc attcgtgacc ctgagtcagg caagtaccag
    17821 ttggaaatca gttctgttta tctggaccac gcgcaaggaa ttgcctccct tctccaacag
    17881 tttttactgg atgccaaggt gcttgagcgc aagaaggggg ctgtgaccta tctccagcga
    17941 gcagaagaca ttatggactt cttgatagta atcggagcca tgcaggcacg tgatgatttt
    18001 gagcgggtta agattttgcg agaaacccgt aacgacctca atcgggctaa taatgccgag
    18061 acagctaata tcgctcggac agtttctgcc agcatgaaga ccattaacaa tatcagtaaa
    18121 atcaaagata tcatgggctt agaaaatttg ccagtagatt tgcaggaagt ggcgcaactg
    18181 agaattcagc acccagacta ctctatccag cagttagcag atagtctcag cacccctctg
    18241 accaaaagtg gtgtcaatca cagactcaga aaaatcaata agatagcgga tgaattataa
    18301 aaccacgaat cctatgtgac tcgtggttct tttttataaa ctagtagagt gttttggttg
    18361 tactttttgt tcagggtcaa tgtacttgat agcgttgttg acagcagttg gagcttctcc
    18421 gaggcctgtc gcaatcagat caatttttcc gtcatagtag cagcagtcac cgatagcata
    18481 gatacctgct tggctggatt cctgtttgct gttgacgata atcttgtgac ggttgaggtc
    18541 gagcccccag tttttaaggt taccgacaga agatttgaaa ccatagttga caaagaggtg
    18601 gtctaggtca atggtttcag tttcatcaga tttgactttt gtgatttcaa gtttagcaag
    18661 tgtttttcca tttccaagga gttggctagg ggcgaatggt gtcttgatgg ttacagatga
    18721 ttcttgcaag gcttgaacac tgtgttccaa ggcacggaaa ttatctctgc ggtgaacaag
    18781 ggtagttggt gcgatttttt caaaagccaa agcccaatcc acagccgagt ctcccccacc
    18841 aagaatcgtc actttcttac cagcgtattg ctgaatgtta gaaacgtggt agtggatatt
    18901 ttcatagccc tcaacacctt caagttccag cggacgtggt ttgaaggcac cgccacccat
    18961 agcgatgatg actgttttag tcaggtgact tcctttagaa gttgtgatgg caaattcttc
    19021 ttcttgtttg tcaatctcaa gaaccgtttc attgagatga ataggggtat caaatccatt
    19081 tagctgttca atcaagcggt tagtcaactc ttctccagtc aggtttggga agcctggtac
    19141 gtctaggatt tccttttcag ggtagagaat agcaggttgt ccacctagct ggggaagaga
    19201 gtcgatgatt tgaaccttgg cttggcgtag gtgggcataa aaggctgcaa aaagcccgac
    19261 aggaccacca cccacaatgg taatatcata gagttgagac atagtttctc ctttgttttt
    19321 tctagtcagt ttattttatc atatttttgt tcaatgtaaa atggactagg atagggaaaa
    19381 aaatgccaga aaatggtata ataggacgaa agtgttttga tagggaggat atcagggatg
    19441 aattttcaac aattatccaa tctgcaatat tggaccagtt tgtttgcaag tccatggacg
    19501 atagctatca atctgattga tattttgatt gttgcttata ttttatacca ttttacaaaa
    19561 gctattgcag gaaccaagat tatgattttg gtacgtggag ttttggtgtt tattttagct
    19621 caaatccttg caaatatgat tggtttgact acgatttctt ggttaatcaa tcaaattatt
    19681 acttatgggg ttattgcggc ggttgttatc ttctctccag agattcggac tggtttggaa
    19741 cgtttgggaa gagcgacaga tttcttttcc aatgccccta ttagtgctga ggaacagatg
    19801 attcgtgcct ttgttaagtc tgttgaatac atgagtcctc gtaaaatcgg ggccttggtt
    19861 gctattcagc gtgtacgtac cttgcaggag tatatttcga caggaattcc cttggatgct
    19921 aagatttctg cagaacttct cattaacatt tttattccca acactcccct acatgatggt
    19981 gcggtgatta tcaaagaaga acgtatcgct gtgacgtctg cctatctgcc cttgacaaaa
    20041 aacacaggga tttccaagga atttgggact agacaccggg cggctatcgg tttatcagaa
    20101 gtctcagatg ccttgacttt tgtcgtatca gaggaaacgg gaggaatttc gataacctat
    20161 aatggaaggt ttaagcacaa cctaacactt gatgaatttg aaacagaatt acgtgaaatc
    20221 ttacttccaa aagaggaagt gggtcttagt tttaaagaac gattgctagg aggatggaaa
    20281 catgaaaaaa aatagtttat atatcatatc ctcactcttt tttgcttgtg tcttatttgt
    20341 ctatgctacg gcgacgaatt ttcaaaacag taccagtgct aggcaggtaa aaacggaaac
    20401 ctatactaat acagtaacaa atgtccctat tgacatacgc tataatagtg ataagtattt
    20461 tattagcggt tttgcttcag aagtatcagt ggtcttgact ggtgcaaatc gcctatcgct
    20521 agctagtgaa atgcaagaaa gtacacgtaa attcaaggtt actgctgacc taacagatgc
    20581 cggtgttgga acgattgaag ttcctttgag cattgaagat ttacccaatg ggctgaccgc
    20641 tgtggcgact ccgcaaaaaa ttacagtcaa gattggtaag aaggctcaga aggataaggt
    20701 aaagattgta ccagagattg accctagtca aattgatagt cgggtacaaa ttgaaaatgt
    20761 catggtgtca gataaagaag tgtcgattac gagtgaccaa gagacattgg atagaattga
    20821 taagattatc gctgtcttgc caactagcga acgtataaca ggtaattaca gtggttcagt
    20881 acctttgcag gcaatcgacc gcaatggtgt tgtcttaccg gcagttatca ctccgtttga
    20941 tacaataatg aaggtgacta caaaaccagt agcaccaagt tcaagcacat caaattcaag
    21001 tacaagcagt tcatcggaga catcttcgtc aacgaaagca actagttcaa aaacgaatta
    21061 aaaatagaaa aggattttat aacaatgggt aaatattttg ggactgatgg agtccgtgga
    21121 gaagctaacc tagaactaac accagaatta gcctttaaac taggacgttt tggaggctat
    21181 gttcttagtc aacatgaaac ggaagcgccg aaagtctttg taggacgtga cacacgtatt
    21241 tcaggggaaa tgctggaatc ggccttggtg gcaggtctcc tttcagtagg gattcacgta
    21301 tacaaacttg gtgtccttgc aacaccagca gtagcttact tggttgaaac tgaaggagca
    21361 agtgccggtg tcatgatttc tgctagccac aacccagccc ttgataacgg aatcaagttc
    21421 tttggcggtg atggcttcaa actagatgat gaaaaagaag cagaaattga agccttgcta
    21481 gatgctgagg aagacactct tcctcgtcca agtgcagaag gcttaggaat tttggtagat
    21541 tatccagaag gcttgcgtaa gtatgaagga taccttgttt caactggaac tcctcttgat
    21601 ggaatgaagg ttgccttgga tacagctaat ggagcagctt ctaccagtgc ccgtcaaatc
    21661 tttgcagacc ttggtgccca attgacggtt atcggggaaa caccagacgg tcttaacatc
    21721 aaccttaatg ttggttcaac acatccagaa gcccttcaag aagtggtcaa agaaagtggg
    21781 tcagctattg gtttggcctt tgatggagac agtgatcgct tgattgctgt tgatgagaat
    21841 ggtgacatcg tcgatggtga caagattatg tacatcatcg gaaaatacct ttctgaaaaa
    21901 ggacaattgg ctcaaaatac aattgtgaca actgttatgt ctaaccttgg tttccacaag
    21961 gccttgaatc gcgaaggtat taacaaggca gttactgcag ttggtgaccg ctacgttgtt
    22021 gaagaaatga gaaaatcagg ctacaacctt ggtggtgaac agtctggtca cgttatcttg
    22081 atggattaca ataccacagg tgatggtcaa ttatcagcag ttcaattgac taaaattatg
    22141 aaggaaactg gtaagagctt atcagagttg gcggcagaag taacgattta tccacaaaaa
    22201 ttagttaata tccgagtgga aaacgtcatg aaggaaaagg ccatggaagt gccagctatc
    22261 aaggccatca tcgagaagat ggaagaagaa atggcgggga acggccgtat ccttgttcgt
    22321 ccaagtggaa cagagcccct cttgcgtgtt atggcagaag cgcctacaac agaagaagtg
    22381 gactactatg ttgataccat cacagatgta gttcgtgctg aaattgggat tgactaaatc
    22441 ctagaaaact agatgaaaat aaaaaattat ggtacaatag cttataatat tgtagccgat
    22501 ggagaaagac atgaatctta aacgtgaaca agaatttgtt agtcagtatc attttgatgc
    22561 gcgtaatttt gaatgggaaa atgaaaatgg agctcctgaa accaaggtgg atgtgaattt
    22621 ccaattgctc caacatgacc aagaaaatca agtgacttcc ttgattgtca tcttgagctt
    22681 tatgattgta tttgataagt ttgtcattag tggaacaatc tcacaagtaa accatatcga
    22741 tggccgtatt gtcaatgaac caagtgaatt gaaccaagaa gaggtggaaa ccttggctcg
    22801 tccatgtttg aacatgctca atcgtttgac ttacgaagtg actgaaattg cattagactt
    22861 accaggaatt aatttggagt tctaatatga aattagctgt tttcacagat tcctctgctt
    22921 atctcagtgc agagaccttg caaagagaag acttgtttgt cttggatatt cctgtcaata
    22981 ttgatggtga ggaatatgtc gaaggcatca atctgtctgc tgaggaattt taccaaaaaa
    23041 tggctcaggc ttctgaattg cctaagacca gtcaaccaag tattgccaag ttagatgaga
    23101 tcttaacttc gctcaaagaa caaggctata cacatgcctt ggggcttttc ctatcttctg
    23161 gaatttcagg tttttaccaa aatatccagt atatggtcga tgactatgag ggcttaacca
    23221 ttgctttccc agacactttg attacaagtg ctcccctagg catcatggtt gaaagcgtct
    23281 ttaattggcg tgatcagggc gatgattttg ccagcattca ggataagcta gccattcaaa
    23341 tcagccgtac gtcagccttt atcatggtag atgacttgga tcatttggta aaaggtggac
    23401 gcctttcaaa tggggctgcc attttgggca atttgcttag cattaagcca atcctttatt
    23461 ttaacgatca aggtatgatt gaagtttacg aaaaagttcg tactgaaaag aaggccacca
    23521 agcgcttaat tgaaattatc aaggaaacaa cggcttcagg tcaataccgg gtcattgtca
    23581 ttcatgggaa tgctcctgaa aaggctgaag aattgcgtca gcatttgctt gattttggct
    23641 tgggttcgga tgtttcactt gctacatttg gtagtgtcat tggaacgcac ctaggatcag
    23701 gaagtattgc tctgggttat attccagtga tttagttggc gcttctaggc tagttaagat
    23761 gccttgtatc ttagaaattg aacacggact acctgcctct tgaaaaaaga tgcctgtctt
    23821 gcctttcgtg gaaagtcagt gccattccct atttttcaga ggcagctaag gtcctttgta
    23881 tcttgataat tgaacacgcc tggaaccctg tgtgaaaaag atagttcttc caagaagtag
    23941 acacttcttg attggaattc ctattttcac tttgtgttct tacggacttt gtatcttaga
    24001 caggagtaga gatgagtatt cgagtaatta ttgccggttt taagggaaag atgggccagg
    24061 ctgcttgtca gatggtattg actgatccag acttggactt ggtagcagtt ttggatcctt
    24121 ttgagtctga gtcagaatgg cagggtattc ctgttttcaa ggataaggct gatttagctg
    24181 gttttgaagc ggatgtctgg gtagatttta ctactccagc tgttgcctac gaaaatacac
    24241 gttttgctct tgaaaatggc tttgctccag tagttggaac gactggtttc acgagtgaag
    24301 aaattgcaga gctaaaagaa ttttctcgtg cccaagactt gggtggcctg attgccccta
    24361 actttgcctt gggtgctgtc ttactcatgc aatttgcgac gcaggctgcc aaatatttcc
    24421 caaatgtgga gattattgag ctccatcatg acaagaaaaa ggatgctccg agtggaacag
    24481 ccattaaaac agctgagttg atggcagagg ttcgagagtc aattcagcaa ggtgcagcag
    24541 atgaggaaga gctgattgct ggtgctcgtg gtgctgactt tgatggtatg cgcatccact
    24601 cagttcgttt gccaggcttg gtagctcatc aggaagtcat ctttggcaat cagggagaag
    24661 ggttgaccct ccgtcatgac tcctatgatc gcatctcctt catgacagga gtcaatttgg
    24721 gaattaaaga agttgtcaag cgtcatgagc ttgtctatgg attagaacac ttattatgag
    24781 attaacgcaa atgccttctg aatttcagaa ggctttacca gtattagaaa aaattaaaga
    24841 agcaggcttt gaggcttatt ttgttggggg ctctgttcga gatgcccttc tccatagccc
    24901 tatccacgat gtggatattg cgacgtcttc ttatccagaa gagaccaagc agatttttcc
    24961 gcgaacagcc gatatcggaa tcgagcatgg aaccgtcttg gtcttagatg gggatgagga
    25021 gtatgaggta acaacctttc ggacagagga tgtctatgtg gactatcgca gacccagtgc
    25081 ggtttccttt gtacgatcgc tagaagaaga cctcaaacgc cgtgatttca cagtcaacgc
    25141 ctttgccttg gatgagacag gagaaatcgt tgacttgttc catggtttag aagatttgga
    25201 aaagcaagtc ttgcgagcag ttggagtggc tagtgagcgt ttcaacgaag atgctttacg
    25261 gattatgcgt ggtttccgtt ttcaggctag tcttggtttt gcacttgagc cagaaacatt
    25321 taaagctatg aagaccttga cgccgctttt ggagaaaatt tctgtagagc gtaccttcgt
    25381 cgagtttgat aaactcttgc tggctccatt ttggagaagg ggcttggctt ccatgattga
    25441 gagtcaagct tatgactatc tccctgatat ggcatctagc caggacaagc tcaacagact
    25501 gtttgatttg gagactgatt ttacttttga atcctctgaa caagcctggg cggctttact
    25561 atgggctttg gagattgaaa atgcgcagtc atttttgaaa tcttggaaga cctcacgcca
    25621 gtttgccaag caagttcagg atttgctgat tattttggct ctgcgtgaaa atggagaatt
    25681 gagcaagcga gattgttatc gctttgacat agatttgctt ttacaggctg aaaatcttcg
    25741 tcaagctcaa ggaaaagaag tcaacccaca agccatcaca gaaaaatacc aaagcttgac
    25801 tatccatgac aagaaagaga ttcagattaa tggcggtatt ttgatcaagg aatatggcta
    25861 tcagccaggc ccagacttgg gagagatttt aacagagatt gagtttgcca ttgtcgatgg
    25921 agaattggag aataatcgtg aagccatcca tgcttacctg agggagaaaa aatgagtgat
    25981 tttatcgttg aaaaactaac taaatccgtt ggtgacaaga ccgtttttag ggatatttcc
    26041 tttattatcc atgacttaga cagaattggt ctaatcggtg tcaatgggac tggcaagacc
    26101 acccttttgg acgtcctttc tggtgtttct ggatttgatg gggatgtcag tcctttttca
    26161 gctaaaaatg attaccagat tggttacttg actcaggatc ctgattttga tgatagaaag
    26221 acagttttgg atacggttct atctagtgaa ctcaaggaaa tccagctcat tcgtgagtat
    26281 gaattgatta tgctcgacta tagtgaggac aagcaggcgc gtttggaacg tgtcatggca
    26341 gagatggact ctctccaagc ttgggaaatc gagagtcagg tcaagaccgt tcttagcaaa
    26401 ttgggcattc aagacttatc tactcctgtt ggggaattgt caggtggtct gagaagacgg
    26461 gtacagttgg cacaagtctt acttggcaac cacgatcttt tgcttttgga tgagccgacc
    26521 aaccatctgg atattgcgat tattgagtgg ctgaccctct ttttgaaaaa ttctaagaag
    26581 accgtccttt ttatcactca cgatcgttat ttcttagacg ctttgtcaac acggattttc
    26641 gagttggagc gagcaggctt gacagaatat cagggcaatt accaggacta tgttcgcctt
    26701 aaggcagaac aggacgagcg cgatgcagct ctacttcata aaaaagaaca actctacaaa
    26761 caagaactgg cctggatgcg cagacaacca caggcacgtg cgaccaagca acaagctcgt
    26821 atcaatcgtt tccatgatct gaaaaaggaa gtttcaggca gtagtgctga gacagacttg
    26881 actatgaact ttgaaaccag tcggattggg aagaaagtca tcgagtttca ggatgtttcc
    26941 tttgcctatg aaaataagcc cattttgcaa gattttaatc tcttagttca ggctaaagac
    27001 cgtattggaa ttgttgggga caatggtgtt ggaaaatcaa ccctacttaa cctgattgca
    27061 ggaagtcttg agccgacagc aggacaagtt gtgattgggg aaactgttcg catcgcctat
    27121 ttctctcaac aaattgaggg tttggatgaa agcaagcgtg tgatcaatta cctgcaggaa
    27181 gtggcagagg aggtcaagac cagtggtggt tctacgactt ccatcgctga gttgctggag
    27241 caattcctct tcccacgttc gacgcatggg accttgattg agaaattgtc agggggtgag
    27301 aaaaaacgtc tttatctcct caaactgctt ttggaaaaac caaatgttct tcttttagac
    27361 gagccaacca atgacctaga tattgcaact ttgacagtct tagagaattt cttgcaaggt
    27421 tttgcaggtc ccgttttaac agtcagtcac gaccgctatt tcttggataa ggtagcgacc
    27481 aagattctcg cttttgagga tggcaagatt cgtcctttct ttggtcatta caccgactat
    27541 cttgatgaaa aagcttttga aacagatatg gccaatcaag tgcaaaaggc cgaaaaggaa
    27601 aaagtggtca aggttcgaga agacaagaaa cgcatgacct accaagaaaa gcaggagtgg
    27661 gcaagtattg aaggtgatat tgaaaccttg gaaaaacgta tcgctgctat tgaagaggaa
    27721 atgcaggcta acggctctga ctttggtaag ctggctactc tccaaaaaga attggatgag
    27781 aaaaatgaag cactccttga aaaatacgaa tgctatgagt atctcagtga atttgatagt
    27841 taagactatt cgaaaatcaa agtgcaaact atgtcggctt cacattgccg actcaagtac
    27901 agcctgtgac cggcttccta atttgcactt tgatttttat tgagtataaa agaatagaaa
    27961 aatcccgtct catgaaagga tttctctatt cttttttggt ttcttgatga aagatatttt
    28021 gccaggtttc gtggcgacgc cagatactgg tatggatgat accatctaac tcatagcaga
    28081 tgagtttggt tttttgactg atggaagtaa tttgaatgtc cttgatagca gaatttaact
    28141 cttttttggt cttataagcc tctttatcca tctgctctcc atcttggcga atatagacaa
    28201 aatcatcagt caagagttct tctagttggt ttccttggtc aatcaattgt tcacgcataa
    28261 gcaatttttt atagacattg tctaaaattt catcctcagg gataggtgct ggttcgatat
    28321 ggacatcggt atcaaagacg ccaaaacgct cctccagcat agactcgacc tgatccgcga
    28381 tttcatggct ttcaaaaaca gacaagtcag gattcatctc tagtgtaata tccaggtaga
    28441 tgttgctacc gtaggtgcga cctctttgcg atttgacctt gctgattttg ggaatttcca
    28501 tgatagcctt ttggtagtcc tcgagcaggc ggtcgtcaaa gccatctgaa agactaaagg
    28561 aagactcgat gaagatatca taggcagtct tcaagataaa gaaagtgatg ataatagcaa
    28621 ccagtttatc cacaatcgga taattaaaac tactagctag gatggcaatg gcggttccaa
    28681 gtgaggtaac agcgtcagaa agattgtcct tagcagctgc cttcagcgcc ttggagttgg
    28741 atttcttact gaggcgagta ttgtagagat agaccacaaa cataatcgct gcagaaatga
    28801 ttcctagagt tgcaccaaga ggatcaatga ccgtttcttc ccgactgaga atcttttgaa
    28861 tggtatctct tagaacatcg aaaccgacat agaacatgat gatagaagtg atcaagcttg
    28921 ccaaatcttc aatcttccaa tgaccaaaac ggtggtcacg gtctgcaggc tggcgcgcca
    28981 tccgaatccc gattaagagg gccacatttc caatgatgtc cgatacgtta ttaaaaccat
    29041 cggccaccaa actggatgaa tgaaggagat gaccagctgc taatttggct gcagacaaga
    29101 tcaaataggt cgaaatactg ataatggctc cacgctcagc taacttgaga tttgagatag
    29161 attgcttcat tcaacttcct ttctagtcac atagcattct accattatac tggttttcaa
    29221 ggaaaaattc aaataaggca gtttttactc tttgaaaact ccccaaaatt tggtataatg
    29281 gtactactca agggagtagc tggcagaaac ctgtgatagt gtcgtcattc cgaattttat
    29341 gctgaaaagt atgctttccg gccctatctt aaacagcgag acttgttatg attaacaggt
    29401 ctctttttgt ttgtcgtgaa aagatatgac agaaagagag tctgttttgc acacaatgtc
    29461 aaggaggaga cacatgtcaa aagaacaaaa acgccaagcg ttttatactc agagccctga
    29521 agaggtcttg caggctgtgg atgcgaccga gcaaggtttg tcatcaagtg aggcggaaaa
    29581 gcgccttgcc gaatttgggc acaatgaact cgaagaaggc gagaaacgat caatcttggt
    29641 caaattcatc gagcaattta aggatttgat gattatcatc ctagttgcgg cagcaatctt
    29701 gtcagtcgtg acttctggtg gggaagatat cgcagatgcc attatcatcc tagctgtggt
    29761 tatcatcaac gctgcctttg gtgtttacca agaaggaaaa gctgaagaag ctattgaagc
    29821 cctcaaatcc atgtctagtc cagttgcccg cgttcttcgt gatggacaca tggcagagat
    29881 tgactctaaa gaattggtac caggcgatat cgttgccctt gaagcaggtg acgtggtacc
    29941 agcggaccta cgtttgatag aagccaactc tcttaaaatt gaagaagcag ccttgacagg
    30001 tgaatctgta ccagtcgaaa aagacttgtc agtcgagctt gcgacagatg ctggtattgg
    30061 tgaccgtgtc aacatggcct tccaaaactc aaacgtaacc tatggtcgtg ggatgggtgt
    30121 tgttgtcaat acaggtatgt acactgaagt tggtcatatt gctggtatgc ttcaagatgc
    30181 ggatgagact gatacaccac tcaaacaaaa tttgaacaac ctttctaagg tcttgaccta
    30241 tgctatcttg gtcattgccc ttgttacttt tgtagtgggt gtcttcattc aagggaaaaa
    30301 tccacttggt gagttgttga cttctgttgc ccttgccgtt gcagccattc cagaaggact
    30361 tcctgctatc gttaccatcg ttctttctct tggtactcaa gttttggcca aacgacattc
    30421 catcgttcgt aagttgccag cagttgaaac acttggttca actgaaatca tcgcttctga
    30481 taagactggt acgctgacta tgaacaagat gacagtcgaa aaagtcttct acgatgcggt
    30541 tctacatgac tcagctgatg atattgaact aggtcttgaa atgccactac ttcgttcagt
    30601 tgtcttggcc aatgatacga aaatcgatgt ggaaggtaac ttgattggtg acccaaccga
    30661 aacagccttt atccaatatg ccttggacaa gggctatgat gtcaaaggtt tcttagagaa
    30721 atatcctcgt gtagctgaat tgccatttga ctctgaccgt aagctcatgt caacagttca
    30781 cccattgcca gatggtcgtt tccttgtagc agtcaagggt gcgccagacc aactcttaaa
    30841 acgttgtctt cttcgtgata aggctgggga tattgctccg attgatgaga aggttacaaa
    30901 tctcattcat acaaacaatt ctgaaatggc tcatcaagcc ttgcgtgtcc ttgcaggtgc
    30961 ttataagatt atcgatagta ttccagaaaa tctcacttct gaagagcttg aaaatgattt
    31021 aatttttact ggtttgattg ggatgattga ccctgaacgt cctgaagccg ctgaggctgt
    31081 tcgtgtggct aaggaagcgg gaatccgtcc aattatgatt acaggtgacc accaagacac
    31141 agcggaagcc attgccaaac gtttgggaat cattgacgca aacgatacag aaggtcacgt
    31201 tttaactggt gctgaactca atgaactgtc agatgaagaa tttgaaaaag tcgttggtca
    31261 atactctgtt tatgcccgtg tgtctccaga acacaaggtt cgtatcgtca aggcttggca
    31321 aaaacaaggt aaagtcgttg ccatgacagg tgacggtgtc aatgacgcgc cagctctgaa
    31381 aacagccgat atcggtatcg gtatgggaat cactggtaca gaggtttcta agggggcttc
    31441 tgatatgatt cttgcagatg ataactttgc gactattatc gtcgcagtgg aagaaggacg
    31501 taaggtcttc tcaaacattc aaaagactat tcagtaccta ctttctgcta atactgctga
    31561 agtattaacc atcttcctat caaccttgtt tggttgggat gtcttacagc cggttcatct
    31621 tttgtggatc aacttggtaa cggatacctt cccagctatc gctcttggtg ttgaacctgc
    31681 ggaacctggt gtcatgaatc ataaaccacg tggacgcaag gcaagcttct tctcaggtgg
    31741 tgttttgagt tctatcattt atcaaggtgt actccaagca gctcttgtta tgagtgttta
    31801 tggccttgcg attgcttacc cagttcatgt gggtgacaat catgctattc atgcagatgc
    31861 cctaacgatg gcctttgcaa cccttggttt gattcagctc ttccatgcct acaatgtcaa
    31921 gtctgtctac caatccatct tgacagttgg cccattcaag tctaagacct ttaactggtc
    31981 catcttggta tcctttatcc ttctcatggc aacaatcgtt gtagaaccgc ttgaaggaat
    32041 cttccacgta accaaactag acttgtcaca atggggaatt gttatggctg gaagcttctc
    32101 aatgattatc atcgtcgaaa tcgttaagtt tactcaacgc aaactcggtt ttgacaagaa
    32161 tgcgatttaa gggaggtttc ggatgtcagc atatcaatta ccgaccgtat ggcaggatga
    32221 agctagtaat caaggagctt ttacggggct aaacagacca acagcaggtg cccgtttcga
    32281 acaaaacttg ccaaaaggag aacaagcttt tcagctttat tcactgggaa caccaaatgg
    32341 tgtgaaggtt actatcttat tggaagaatt actagaagct ggttttaagg aagcggctta
    32401 cgacttgtat aagattgcta tcatggatgg ggatcaattc ggctcagact ttgtgaagct
    32461 caatccaaat tccaagattc cagccttatt ggaccagtca ggtactgaaa acgtaagagt
    32521 ctttgagtct gctcatattc ttctttacct tgctgagaaa tttggagcct ttttaccaag
    32581 taatcctgtg gaaaaggtag aagttttgaa ttggctattc tggcaagtag gtgcagcacc
    32641 ttttctaggt gggggatttg gacatttctt caattatgct cctgaaaaat tggaatatcc
    32701 tattaaccgt tttacgatgg aagtgaaacg ccagttggat ttattggata aggaattggc
    32761 tcagaaacct tatattgcag gcaatgacta tacgattgca gatattgcta tctggtcttg
    32821 gtatggacag ttagttcaag gaaatcttta ccaaggttct gcaaaattct tggatgcctc
    32881 aagttatcaa aatctagtaa aatgggcaga aaaaattgcc aatcgtccag ctgttaagcg
    32941 tggcttggaa gtaacttata cagaaattaa atagcaaaaa agtcatcttc ggatggcttt
    33001 ttgctacagt tgagggaaag ggtttgcagt tatcggcttt tgtgctataa ttgctataat
    33061 atagtaaaaa gcaagaggag tgtgaggaag tggaaaagaa aattgtgaag gatatcttat
    33121 ttttatctca agtgtctcag ccggcaagtc aggaggacct ttatcttgcc agagatttgc
    33181 aggatacact cttagcaaat cgtgatacct gtgttggtct agctgccaat atgattggga
    33241 tgcagaagcg cgtgattatc tttaatcttg gcttggttcc cgtggtcatg tttaacccag
    33301 tgcttctgtc ctttgaagga tcctatgagg cagaagaagg ctgtttgtcc ttggtaggtg
    33361 tgagatcaac taagcgttat gaaaccataa ggcttgccta tcgtgacagc aagtggcagg
    33421 aacagaccat taccttgaca ggcttcccag ctcagatttg ccagcatgag ctggatcact
    33481 tggaaggacg aatcatttag gaggaaagca aatgaaacga atagtctttg aacttatttt
    33541 tatcgcaacg acctggtata tctttttacc gccccttaac ctgaccagct gggaatttct
    33601 cttcttcctc tgtgggcatt tgttagttgt ggcaatctta tttggctttg gcaaggggat
    33661 aaaccttgtc aaaacggttc atgtgcgcca cggtaaggcg gaagctgcct taaatcttga
    33721 gggtttcaaa atcaatcggt tagggaaaat tctgttagct tcgattggag gaattcttct
    33781 cttggcagct ttggtttcct tggtaacttc tagcatgttt caggctaaaa attatgccaa
    33841 tgtagtcacg gttacggaaa aagactttac tgaatttcct aagagtgaca ccagtaaggt
    33901 tcctatccta gatagaagta ctgctgaaaa aattggagac cgctacttgg gttccctaac
    33961 cgataaggtg tcgcaatacg tagcggcaga tacctatacc caattgacaa ttgatgggaa
    34021 accttatcgg gtcacaccac tagaatatgc agaccctatc aaatggttta acaatcaagc
    34081 caagggaatc ggtgagtata tcaaggtgga catggtaact ggaaatgcgg atttggtgga
    34141 cttgaagaca ccaatcaagt attcagactc ggagtatttt aaccgtgatg tcaaacgtca
    34201 cctgcgcttg aagtacccga ccaaaatctt taaaactcca tcttttgagg tggacgatga
    34261 gggcaatcct ttctatgtag caacggttta ccaaaagcaa tttggacttg cggttcctcg
    34321 tcctgcttca gtcattatct tggatgctac aaatggagaa accaaggaat acagcttatc
    34381 agacgttcca gaatgggtgg acaggatcta tccagcagag gaaaccattg agcaaatcaa
    34441 ctacaacggc aagtacaagg acggtttctt gaatgccatg atttccaaga aaaacgtgac
    34501 ccagactacc aatggctata attacttgtc tatcggtaat gacatctatc tctacacagg
    34561 tgtgacgtcg gctaatgcgg atgagagtaa tcttggtttc atccttgaaa atatgcgaac
    34621 aggagaaatc actaagtata gcttggcttc tgcgacagaa gaatcagccc gtgaatcagc
    34681 agaaggtgct gttcaggaga aatcctacaa agcaaccttc ccaattctca tcaacctcaa
    34741 tgacaagcct ctctacatca tgggcttaaa ggacaatgct ggcttgatca aagagtacgc
    34801 cctggtagac gcagtcgagt accaaaatgt tatcgttgct actacagtgg aagagatgct
    34861 cagcaagtat gccaataaaa acgaccttga aattgacaat gcaacgacag aaagcatcaa
    34921 gggagtagta gcagacctca aatcagctgt tatcaaggga gacactgtct acttctttaa
    34981 agttgatggc aagatataca aggtaaaggc ttcagtatcc gatgaccttc cttaccttga
    35041 aaatggtaaa accttcgaag gtcaagtagg aaaagacaat tatctcaaga cctttaaagt
    35101 acaataatac tcttcgaaaa tctctagctc tatctgcaac ctcaaaacag tgttttgagc
    35161 agcctgcggc tagtttccta gtttgctctt tgattttcat tgagtataaa aaaggtttat
    35221 ttaataaata tatgttataa taaggtaaat taagcctaat ggaggacaaa gaaatgggtt
    35281 tttatttgat ggttgcttca atgctactcg gactgctcgc tttgaagata ggtttttctc
    35341 agttcaagga gaaaaaagat aaattcttat ctatcttaac aagtttagct ggcatagccc
    35401 ttgttctcgc ggctgtctgg ttaggatggc ccaaataaat agaaaaacct cggtcaaacc
    35461 gaggtttttc aaatgaattt cttggttgtg gctaaaaaat atgctacact atcaatatga
    35521 aaattttaat cccaacagca aaagaaatga acacagactt gccaagtatc gaggcaattc
    35581 ctttaaaacc agaaagtcag accgtgcttg atgccttggc tctctattct gccagtcaat
    35641 tggagagttt ctacaaggta tcagctgaga aagcggcgga agaatttcaa aatatccaag
    35701 ctttgaaaag gcaaactgct caacactatc cagccttgaa actttttgat gggcttatgt
    35761 accgcaacat taagagagat aagctgaccg aggcggaaca agattatctt gaaaatcatg
    35821 tcttcattac ctcggctttg tacggtgttg ttccagcctt gtcacccatg gctcctcacc
    35881 gtttggattt tttgatgaaa ttaaaagtcg ctggtaagac tttgaagagc cattggaagg
    35941 cagtctatga tgaagctctg aagaaggaag aagtgatttt ctctctcttg tcatcagagt
    36001 ttgagactgt attttctaag gaaatcagag caaagatggt gaccttcaaa ttcatggagg
    36061 atagaggcgg tcagctgaag attcactcaa ctatctccaa gaaagcgcgc ggggcctttc
    36121 taacagcttt aatagaaaat caagtacaaa ctgtggggga agcacgtcgc ttgaactttg
    36181 ctggatttgt ttaccgagaa gatttgtcac aaccacaggg attggttttt gtaaaggaag
    36241 tatagaaatc agataagaga aaagtcagca cgattatgct gacttttttg ataacttata
    36301 aagtattgga caaatgaatc tcatttgata aggtgttaag atgattaacc aaattcatga
    36361 ttgacagatg atttcggcaa ataaacttct tggtaatccc tggaatatag aaattagaca
    36421 cgatgatatc gtaatctgtc tgatttaaaa tctcaggact tgtttttaat tcatcccaaa
    36481 tatcgaaggt aaagcggtta ttacagtaat aggaaagcat atcaacaaag gtaagggata
    36541 tagcatggtc aaagttactg ataatcaaaa ccttgatagg tggtcgattt tctaacaact
    36601 gagtagagag gttttcagca tgggttaaga tggtgtacat caagtgttcc aactgttcag
    36661 gatggtcatg ctgtccaatt gcctgacggt attgagccag ttcttgacgc gcacttccca
    36721 taaagtctgg gaagtaaact tcaaattttt taatcgtcaa tgctttttgt tcaaataaga
    36781 ttggggtaga aaagatttcc tgtctttcaa agaaagcagt gttgtgtaaa tgccaaatca
    36841 gctcatcgtg gttagtaaaa gtaatcttat attgttttga taggcgttct aatatttgac
    36901 taagtaattg gtaagagtat cttgcttgac tgttatcttc taaagagttg aagaattctt
    36961 gaggatctag gaaaatatca ttctgaagaa aagaaataaa aatttgagcg attgtatctg
    37021 gagtcatttc aagcccaaaa tgtttagaga aataagcaag tgtctcctgg aaatttggaa
    37081 tgctctttaa aagaggataa tattctttgt aaaagtggtt ggggaggtca atgaagtgac
    37141 catttttaac cctgtggata ctgatagcta tcatcagttt gtacattcta taaattgaaa
    37201 atcgcattgg ataattcgtg attttataga agaagtcagc aaactctgtt aaatcttcct
    37261 caggaaggtc aggaaaaggc caatctagga aataatagcg ctcagaaaag tattgggcaa
    37321 aaaagtaacg aatatcgatc tcatttccac gtatctcgga tggagtaaaa gataattcaa
    37381 tttgaaactg agatgaaaga acctttgtaa tatttctgcc cagtcgatag aggttggcac
    37441 tactaaagta aagattttct attgttcgat aaataggtag cccctcattg aagaacatat
    37501 actctagtaa ttgaaaagat tgagaattag caagaaaata ttgataaata tcttctacac
    37561 tagtgttaac ttctaaatct atcatgattc cgttaacaga agattggatg ttaatagatg
    37621 gaaaggcaat acgtaattca tttaaatcac tttttaagat tcgttctgtg catcctaatt
    37681 tttcggctag ttcatgtaat ttcatccaat tacgattctg aattagggtt tccattaagc
    37741 gtaattgtct ttgaactttt gtggataaaa ggtttctcat acgggtattt cctccataat
    37801 tcattatatc tttttttgtc taagtagtat aaaaaaatta gagtaagaaa attgtcgtta
    37861 gtaatcggaa aaattagaat aatataagtg gctttcaagt gcaaaaacag aatatattaa
    37921 ttgttcagaa aatattgatt aatgcctcaa atagttgtac attgtaaact ataaaatact
    37981 atctaggagt ttaaaatgaa acattcacat aaaaaatcat ttgactggta tagcatgcaa
    38041 caacgttatt ctattcgtaa gtattacttt ggtgcagtta gtgtcttgct cggtaccgct
    38101 ttggtattag gtgcagcagc tagtgtccaa acagtacaag cggaagaaaa caaacaagaa
    38161 actaccaata gtatttctgt tggtagggga gaagcagcta ctaaaccagc agaggtttct
    38221 gcgtctaata aagagaaaac ctatgcagct ccaactgtag ctaatccagt agaaacgact
    38281 ccagttaaaa ctggagaagt tactaaacca gcagaaaaag ttgaagaagc aaaaaacaaa
    38341 aaagaggaag taacgcatca agatgctatt gacaagtcaa aattgttaac ggctctttcg
    38401 cgtgctaaaa agttagaaag caagttatat acagaagcaa gtgctgctaa cttgcaaaca
    38461 agtatccaag ctggtcaaag cttgcttggg aaagcagatg catctgaagc tgaattatca
    38521 gcagcagagt catctattca atcatctatt attggtctag aacttcgttc taactctaac
    38581 aaaggaactg tatcagaaac tcctgtagcg aagaaagcta atatagttga agcgaaggaa
    38641 gagactaatc cagctgcaac aactgatcgt tcagctgttg atagtgctgt tttgccaact
    38701 agcacagctg ccaaagtaga aacaacttca gctccagcat ctattaatga aatcttgaaa
    38761 ccaggtttga gcctttctga tgctcgccaa aatccagcta tccgtaagga agatgttgat
    38821 agagggtata gtggttttag agcggcgcct gctccaacga accaaccagt aactaatcta
    38881 ggaaataata ctgttttcac tgatattagc agaggttctc atactttccg tggtaatgga
    38941 aattcacgtc gtggaaaccc gattcatttt gatgtaacaa caactagagt tagaaataga
    39001 gtagatttct caatcagata ttcaggacca ggtgagtttg ttaataacaa ctttatctta
    39061 gacaaaggaa atggattcgg agaaccttct cgtgcaactg tttcaacacc aaaattaaga
    39121 gaccaagtta aaaacattag taagggtgga aactttgttt ctcattcagg ctacagttta
    39181 gaagctgcag tagaaacaag caccaatcaa acaattaagt ttagtttacc tatagccaac
    39241 cctaatggtg atctgtctgt tcgattaaga cctgttactt ttaatgtagg tcaaggggaa
    39301 tcaggatctg caactagtaa tgatccatat agtaactcta actattactt cagagaaaaa
    39361 ccactcctct tggatgcaaa tccaaatggt ggtactaata ataagactgt ttcagaagac
    39421 attgacttcc aaactgtcta tcttccaact agtaagttac cagaaggtca aactagatta
    39481 gttcgagaag gtgaaaaagg acaacgtcaa attacctata aagttcatcg atttggtaac
    39541 gaaacagtct taggattgcc aattagtaat agagttacta aagaagctaa gccacgtatt
    39601 atgcaaattg gtgtggctaa agagctaatc gatacagtaa aaccacgtgt tgatcaaaat
    39661 aaagttggtg atacaaataa cctcactttc tatcttgata acgatggcaa cggtgtttat
    39721 actgaaggtg tagacgaact tgttcaaaaa attgctatta aagatggagc taaaggtgaa
    39781 aaaggagacc aaggtgaacg cggtctaact ggagctcaag gagctaaagg tgaaaaagga
    39841 gcccgaggcg aacgcggtct aactggagct caaggagcta aaggtgaaaa aggagaccga
    39901 ggtgaacgcg gtctaactgg agctcaagga gctaaaggtg aaaaaggaga ccgaggtgaa
    39961 cgcggtctaa ccggagctca aggagctaaa ggtgaaaaag gggaccaagg tgaacgcggt
    40021 ctaaccggag cacaaggtgc taaaggtgaa aaaggagccc aaggtgaacg cggcctaact
    40081 ggagctcaag gagctaaagg tgaaaaagga gaccgaggcg aacgcggtct gactggagcc
    40141 caaggtgcta aaggtgaaaa aggagcccaa ggtgaacgcg gtctaaccgg agcccaaggt
    40201 gctaaaggtg aaaaagggga ccaaggtgaa cgcggtctca ctggagccca aggtgaaaaa
    40261 ggagcccgag gcgaacgtgg tttaactgga gctaaaggtg aaaaaggagc ccaaggtcag
    40321 gcaggtcgtg acggtgtaac tccaaccgta accgttaaag ataataaaaa tgacggcact
    40381 catactatca ctattaacga cggtagaggt aatgttacaa gtactgttgt aagagatggt
    40441 ttcgatggcg caagtccatt agttgagact caacgaaatg acgcagataa gacaacaact
    40501 gttatcttct attacgataa aaatggaaac aatgaattag atgcttctga taagaaatta
    40561 aaagaagttg taattgcaga tggtgctaaa ggtgaaaaag gggacaaagg tgaacaaggt
    40621 cttcaagggc gtgatggtga acaaggacca aaaggagaag atgggaaaac cccaacagtt
    40681 aaagtaactg atggtcaaga tggaacgcat acaattacaa ttaacgatgg taaaggtggt
    40741 ataactacta cagtagtaag agatggattt gatggtgcaa gccctcttgt ttctactcat
    40801 agaaatgaag cagataaaac aacaactgtt attttctatt atgatctaaa tgataataat
    40861 caatttgatg aaggagatac aaaacttaaa gaagttgtta tcgcagatgg aaaacaagga
    40921 ccaaaaggtg acaaaggtga taacggaaaa gatggattca caccagaagt aacagttaca
    40981 gataacaata acggaacaca caccatcaca atcacacaac cagacaacag accatcatta
    41041 acaacaatcg ttaaaaacgg tgaagatgga aaaacaccaa aagtcaaagc agaacgagat
    41101 gatgcgaaga aacaaacaac attaacattc tacattgaca aagatggaga tggaagttac
    41161 acagcaggaa aagacgagtt agttcaaaca acagtagtta aagacggaca agacggagct
    41221 gcaggagcat ctggacgtga tggaaaagaa gtattaaacg gaaaagtaga cccaacaaca
    41281 gaaggtaaat atggagacac attcgtaaat acacaaacag gagatgtatt cgttaagaaa
    41341 ggtaacactt gggaaccagc aggaaacatc aaaggaccaa aaggtgacaa aggtgcagac
    41401 ggtgccaagg gtgaaaaggg agatcagggt gaacgcggtc taactggatc taaaggtgaa
    41461 aaaggagacc aaggtgaacg cggtttaact ggagcgcaag gtgccaaagg tgacaaaggt
    41521 gaacaaggtc ttcaaggtcg tgatggagct caaggaccaa aaggcgcaga tggacaaaga
    41581 ggaccagcgg gaccacaagg accaaaagga gaacaaggta atccaggaac tccaggtaaa
    41641 gatggaaaat ctctaattgc tgttaaaaat ggaactgaaa caaaagtcta tgtagaggat
    41701 ccggctagac caggacaacc acttaatcca aaccaaccat tagcaactat cactgatgga
    41761 agaaacggta ctaatggaca atcaccaaca attacagcga cacgaagtgt gcaaaatggc
    41821 aaaaatggtg tattagtaac aattacacca gtaggaggtc gtccacaaac aacatttgta
    41881 gaggatggac aaaagggtgc tgatgggaaa accccaacag taacaataac tgaggggcaa
    41941 aacggcacac atacattaac ggttcataat ccaggaagtc cagatgtgac aactacgatc
    42001 cgtgatggag ctacaggaca agcaggtcgt gatggtaaag atgtattaaa cggaaaagta
    42061 aatccacaac caaaccaagg taaaaatgga gataaatata ttaataccga aaccggtgat
    42121 gtctatgtta aaaacaatgg aaactgggat aaagaaggca acatcaaagg ccctaaaggt
    42181 gacaaaggtg cagatggtgc taaaggcgaa aaaggagacc aaggcgaacg cggcctaact
    42241 ggagcgcaag gagctaaagg tgcggatggc gcagtaggtc gtgatggacg tgacggtaaa
    42301 gacgtgttga acggcaaagc taacccagaa gcacatcaag gtaaagacgg cgataaatac
    42361 gttaatacag aaacaggcga cgtcttcgtt aagaataacg gcaactggga taaagagggc
    42421 aacatcaaag gccctaaagg tgacaaaggt gcagatggtg ctaaaggcga aaaaggagac
    42481 cgaggcgaac gcggcctgac tggagcgcaa ggagctaaag gtgcggatgg agcagcaggt
    42541 cgtgacggac gtgatggacg tgacggtaaa gacgtgttga acggcaaagt taacccagaa
    42601 gcaaatcaag gtaaagacgg cgataaatac gttaatacag aaacaggcga cgtcttcgtt
    42661 aagaataacg gcaactggga taaagagggc aacatcaaag gccctaaggg tgacaaaggt
    42721 gaacgcggag aagatggtaa gactccagaa gtaactgtaa ctccaggtaa agatggccat
    42781 agtactgaca ttacattcac tgttccaggt aaagatccag ttacagtaaa tgttaaggac
    42841 ggagaaaatg gtctgaacgg taaaactcca aaagttgatt tacttcgtgt ccaaggaaaa
    42901 aacggaaatc catctcatac aattgtgaca ttctatacag atgaaaacaa tgacggcaaa
    42961 tatacaccag gaactgatga acttctaggt tcagaaatga ttaaagatgg tgctaaaggc
    43021 gcggacggac gagatggtaa atcattgctt actgtcaagg atggtaaaga aactaaagtt
    43081 taccaagaag atccagctaa cccaggacaa ccattaaatc cagaaaaacc acttgcggta
    43141 attagagatg gagtagatgg aaaatcacct acagttacag ctgttcgtaa agatgaagca
    43201 gggcataaag gtgtagaaat cactgttgat aaccatgatg gttcacaacc aactacagtc
    43261 tttgttcaag atggtgctaa gggagaaact ggtgcaatcg gtcaggatgg acaaactcct
    43321 acaatcacta ctcaacgtgg acaagatggc caaagcactg ttgtaactat cacaacacca
    43381 ggtaaagatc cagtaacctt cactgtaaaa gatggtaaga atggtaaaga tggccgtgca
    43441 ccgaaaatca aagtagaaga tattacttca ccttcaagaa ttagacgcgc tacagatgct
    43501 gctgcaactc caacgcgtaa cggtatccgt gttacagttt atgatgatgt taatgacaat
    43561 ggggtatacg acggaggtgt cgataaagta ttaaatagta aagatattta taacggtata
    43621 gatggacgtg atggttcagc tccaactatt actacaaaag ataatggaga tggaacacac
    43681 actatcacag ttcaaaatcc tgatggttct gaatcaacaa ctgttgttaa agatggtaaa
    43741 gacggtaaaa ctgcgaatat cactacaaca gaaaacccag atggaagcca cacaattacg
    43801 gtgacaaatc cagatggttc aactaaagaa actgttgtta aaaacggtaa agacggtaag
    43861 actcctaaag ttgaagtaac ggataacaac gatggaactc acacagttaa agtgacggat
    43921 ggagacggta atgtaacgaa cgctatcatc aaagatggta aagctgcaac agcaacaact
    43981 actgaaaatc cagatggaag ccacacagta acaatcacta acccagacgg aactaagaat
    44041 gagtttgttg ttaagaatgg acgtgacggt gttgacggac gtactccaac cgcatctgtt
    44101 cgtgataatg gagacggaag tcatacaatc gttattacaa atccagaagg tgtgacaact
    44161 gaaaccacag ttcgtgacgg taaatcacca actgctaagg ttgtggataa cggagatgga
    44221 acacacacta tcacagttgt gaactcagac ggaacaacta caacaactac agttcgtgat
    44281 ggtagagaac caaaacttga agttattgat aacaacgatg gttcacacac tattaaagtg
    44341 acaggtgctg atggtaaaga aacgacaact acaatctttg atggtaaatc accaaaagcg
    44401 aacatcgttg ataacggaga tggaactcat acattaacaa tcgtagattc tgatggtcgt
    44461 gaatacaaat ctattattaa agatggtaaa gacggcaaag atggcgtttc accaactgta
    44521 actgttgaaa ataataacga tggaactcac gttgttacaa tcactaatcc agatggaagt
    44581 aagacagaaa tggtgattaa agacggtaaa gatggtaaat caccaaaagt ttctgttgaa
    44641 gataatggtg atggtagtca tacaatcaca atcatcaatt ctgatggaac tgtgacaaaa
    44701 acagttatta aagatggcaa agatggtaga gatggacgtg atggtagaga cggcaaagat
    44761 ggaaaatgtg gatgccaaga caaaccagta acaccatcaa atgacaaacc agttcctcca
    44821 acaccaaatg tgccgacacc agaagtaccg gttaaacctg tgccagcgca accaacacca
    44881 aatgtaccga caccagaagt gccagtacaa ccaactccag ctgttccaac accagaagta
    44941 ccggttccag aacaaccagt agtaccaaca ccggctcaac cagcaactcc agtaaatgct
    45001 aatccagtag caccaactac aggtaaagaa aaccgtgggg acaaattacc tgaaactgga
    45061 agccaatctg attatatctc tgttctttta ggtagcggta ttctattgag cctatatgta
    45121 ggacgaagaa aagaagatta atcagccaaa agcagtcact aatttctcga aagaagatga
    45181 taagtgatag atctcgaatg aaagaatatt cttagaatga ttttcctatg atggaaaaga
    45241 ctgctaaaaa ccttgagtgg taacgctcaa ggtttttttg gatggctgat gtttgtctga
    45301 aaatcttgat tgagaaataa aaagccaccc tattaggtgg ctataattga tttagacttt
    45361 ctaaaatttt ctatttttta ctgaatcgct tcgaccaagt cttgagcttg tttttcaagt
    45421 gagtttagga ctgtttcttc aagaaccaat tttccgtctg cccaggcaga gtcattaaca
    45481 cgtgcagcag tgaaatcacc aacgccttgt gtacggataa atggcaagag gtctttgtag
    45541 atagcgaaaa gttgatcgtg ccctgcattg gctacagatg atactgtgac aaacttgtct
    45601 tgacgggcag aagcgccacg tgtatcagac aagtcaaggg cacgagatag ccagtcaagc
    45661 aagtttttta ctgtaccagg gatagagaag ttgtagactg gagagaaaat ccagatagca
    45721 tccgcaacga gaactgcttc acgagcagca gctacagctg gatgtgttgg aacttccaaa
    45781 tcttggctga agagaggaag ggctgaataa tcaaggtagc taacttccgc tttaccagca
    45841 agtgctttct cagcttcgag cgccatttgg tggttgaaag aaccttgacg tagtgatccg
    45901 acgataaata atactttttt agacatgatg tgtctccttt ttcttaaaat ttcgagaact
    45961 ctctcgttgt tataaaatat attacaacaa aacaaaagaa cttgcaagaa atttgctcag
    46021 agtttatttg aaaattgtaa aatttcggaa actctaatca tttgtgactg aaaaagtaag
    46081 aactgtttca ctttcaaaat cggttttgtt tgaagggaga aatagaattg gttgctcaaa
    46141 gcacagcttt gaggttgcag ataaagctga cgtggtttga agagattttc gaagagtatt
    46201 cttatattca cttgtaataa agcttaatag atggtaaaat agacgagtga aaaaaagaca
    46261 aaacaaagca aaaaataatc tactgtggca gtatggtcta gggatgacga ttttgtttgt
    46321 ggttatcagt gcttcctttc tgtatatggt ttctcttagc atgaaaccct atcaaacagc
    46381 taaaagtgaa ggagaaaaat tagctcagca gtatgcagga ttagagcagg ccgatcaggt
    46441 tgatttatac aatggcttgg aatcttatta cagcgttctt ggtcgtaata aacagcaaga
    46501 agcacttgct gttctgattg gaaaagatga tcataagatt tacgtttatc agctaaatca
    46561 gggtgtttca caagaaaaag cagaaacggt ttctaaggaa aagggagctg gcgaaattga
    46621 caagattatc tttggtcgtt atcaagataa gccaatctgg gaagtcaagt caggatctga
    46681 tttttatcta gtagattttg aaacaggagc attggtcaac aaggagggcc tatgaaatta
    46741 tccaaccgtg ttttagaaat ggaagaaagt gtgactttgg ctgctggagc ccgtgccaaa
    46801 gcactgaagg ctgagggtag agatattttg tctctaacct tgggtgagcc agatttcact
    46861 actcccaaaa atatccaaga tgccgccatt gcatcgattc gagatgggcg tgcttctttt
    46921 tatacagtaa cctcaggtct gccagagctt aaggcggcgg tcaatagcta ctttgagcgc
    46981 ttttacggct attctgtagc gtcaaatcaa gtgacagtcg ctgcgggagc caaatattct
    47041 ctctatacct tctttatggc tgtggtcaat ccaggtgatg aagtcatcat cccaacccca
    47101 tactgggtta gctatggaga tcaggtcaag atggcagaag gcgttcccgt ctttgtttct
    47161 gctaaggaag acaatcactt taaggtgacc gtagagcagt tagaagcagc tcgcactgac
    47221 aagaccaagg ttttggtgct gaattcgcca tctaatccca caggtatgat ttacacccgt
    47281 gaggaactct tggcaattgg aaactgggct gtagaaaatg atattctcat cctagcagat
    47341 gatatctatg gccgcttggt ttataatggt catgagttca caccgatttc tagcctatcg
    47401 gaagcgattc gcaagcaaac agtggtcatc aatggtgtgt ctaaaaccta tgccatgact
    47461 ggttggcgga ttggttatgc cgttggagaa gcagacatta tcgctgccat gtccaagatt
    47521 gcaggtcaaa caacttcgaa tccgtcagca gtagcccaat atgcagcagt tgaggctcta
    47581 tcaggtgagc aagatactgt agaaagcatg cgtcaggcct ttgaagaacg tcttaatacc
    47641 atctatcccc tccttgcaga agtgccagga tttgaagtgg tcaaaccgca aggggccttc
    47701 tatctcttcc caaatgtcaa aaaggccatg gagatgaaag gctacacgga tgtgacagac
    47761 tttacaactg ttatcttaga agaagccgaa gtggccttgg taacaggagc tggatttgga
    47821 gcaccagaaa atgtccgcct cagctatgcg acagacctag acacgcttaa agaagcagtc
    47881 gaacgcttga aagcatttat gggtagtgag aatgattgat cattttgaga ttaaggtaaa
    47941 ggatttacaa atttcagaag gattttatag gagttttctc gctcctttgg actataaatt
    48001 ggcttttaag actagttctc taattagttt tctatccccg aacagccctc atcctggtgg
    48061 tgatttttgg ctgactcagg gaacacaaga tcctgttcat tttgcttttt tagcagaaaa
    48121 taaggaagaa gttcaggctt gttatgaggc tggcttagag gcaggtgggc gagacaatgg
    48181 ggctcctggt tatcgaagtg agcatccgat ttactatgct gcttttatga ttgacctgga
    48241 tgggaacaat atagaggtgg tttgccataa agaataaaaa agaaaaggaa aaataatgac
    48301 aaaacgtgta acgattattg acgtaaaaga ctatgttggt caggaagtga cgattggcgc
    48361 ttgggttgcc aacaaatcag gaaaagggaa aatcgctttc ttacaattgc gtgatggaac
    48421 agccttcttt caaggtgtgg cttttaaacc aaactttgtc gaaaaatttg gtgaagaagt
    48481 gggacttgag aagtttgatg ttatcaaacg cttgagccaa gaaacgtctg tttatgtgac
    48541 aggtattgtc aaagaggacg aacgttctaa atttggctat gagttggaca tcacagacat
    48601 cgaagtgatc ggtgaatctc aagactaccc aatcacacca aaagaacacg gaacagactt
    48661 tttgatggat aaccgtcact tgtggctacg ctctcgtaag caagtagctg tgttgcaaat
    48721 ccgtaacgct attatctatg caacttatga gttctttgac aagaacggtt ttatgaagtt
    48781 tgacagccca attctttcag gaaatgcggc agaagattct acagaactct ttgaaactga
    48841 ctacttcgga acgccagcct acttgagcca atcaggtcag ctttacctag aagcaggggc
    48901 tatggctctt ggtcgtgtct ttgactttgg tccagttttc cgtgctgaaa aatcaaaaac
    48961 acgccgtcac ttgactgagt tctggatgat ggatgctgag tactcatact tgacacatga
    49021 tgagtcgctt gacttgcaag aagcttatgt gaaagctctt ctacaaggtg ttcttgaccg
    49081 cgcgcctcaa gccttggaaa ccttggaacg tgatacagaa ctcttgaaac gctacattgc
    49141 agagccattc aaacgtatca cttacgatca agccattgac ctcttgcaag agcatgaaaa
    49201 tgatgaagat gctgactacg agcatcttga gcatggtgat gactttgggt caccacacga
    49261 aacttggatt tcaaaccact ttggtgtgcc aacatttgtc atgaactatc cagtagccat
    49321 caaggccttc tacatgaaac cagttcctgg aaatccagag cgcgtgcttt gtgcagactt
    49381 gcttgctcca gaaggctatg gagaaattat cggtgggtct atgcgtgagg aagattacga
    49441 tgcccttgtc gctaagatgg atgaacttgg catggatcgt acagaatatg aattctacct
    49501 tgaccttcgt aaatacggta cagttccaca cggaggattt ggtatcggta tcgaacgtat
    49561 ggtaaccttc gcagcaggaa caaaacatat ccgtgaagct attccattcc cacgtatgtt
    49621 gcaccgtatc aaaccataag aacaggaaaa cgcccatgtg gcgttttttc gaattctagt
    49681 gtttttactt gcgtaaaaaa attttttcta gtataatagt ttactgtgag cgaacctcac
    49741 ttaccccttg caaagtcttg gggtcattag accaaaagga ggaacatatc aatggctaaa
    49801 tacgaaattc tttatatcat tcgtccaaac attgaagaag aagctaaaaa cgctttggta
    49861 gcacgttttg actctatttt gactgacaac ggtgcaactg ttgttgaatc aaaaacttgg
    49921 gaaaaacgtc gtcttgcata cgaaattcaa gatttccgtg aaggacttta ccacatcgtt
    49981 aacgttgaag caaatgacga tgcagctctt aaagagtttg accgtctttc aaaaatcaac
    50041 gctgacattc ttcgtcacat gatcgtcaaa attgacgcgt aagaaggtaa actatgatta
    50101 acaatgttgt acttgtaggg cgtatgacac gtgacgctga gttgcgttat accccatcaa
    50161 atgtagcagt tgcgactttt actcttgcag taaaccgtac atttaagagt caaaatggtg
    50221 aacgtgaggc tgattttatc aatgtcgtta tgtggcgcca acaggctgaa aatcttgcta
    50281 actgggctaa aaaaggctca cttatcgggg tgacaggtcg tatccagact cgtagttacg
    50341 ataaccagca aggacaacgt gtctacgtga cagaggtcgt ggctgagaat ttccaaatgt
    50401 tggaaagccg tagtgtgcgt gagggtcaca caggtggagc ttactctgca ccaactgcaa
    50461 actattcagc acctacaaat tcagtaccag acttttcacg taatgaaaat ccatttggag
    50521 caacaaaccc attggatatt tcagatgatg atttaccatt ctaatggaca actaaactta
    50581 taaaggagaa aaaacatggc tcaacaacgt cgtggcggat tcaaacgccg taaaaaagtt
    50641 gattacatcg cagcaaataa aattgaatat gttgattaca aagatactga acttcttagc
    50701 cgtttcgttt cagaacgtgg gaaaatcctt cctcgtcgtg taacaggaac ttcagctaaa
    50761 aaccaacgta aagtaacaac agctatcaaa cgtgctcgcg taatggcttt gatgcctttc
    50821 gtaaacgaag attaaagaaa agacccggtt gggtctcttt ttcatgagct tgaaaacaag
    50881 aaagcgaatt aagaccccaa cgggtctttt ttcacaagct ttgaaatgag agagcgagtt
    50941 aggctcagtg gctccctttt tacgagtttg aaaacaagag aacacattaa aagcacgatg
    51001 gagctttttc ataaatatgt ctcttttctc atccaagaaa ttaaaataaa aatgataaac
    51061 tttttgaaaa taggggattt gcctacttta tgatataatg gaaagagtta gattgaaaga
    51121 ggtagtgaga tggacgcgaa attaagatac aaggcaaaga agatcaagat tgtctttttt
    51181 gatattgatg atacattgcg gaattcaaag acagggttta ttccaactac aattcccact
    51241 gtttttaaac agttgcgtga aaaaggaatt ttaacaggaa tcgcctctgg acgtggcatt
    51301 tttggtgttg ttccagagat tcgtgatctc aagcctgact tttttgtaac tttgaatggg
    51361 gcttacatcg aagataaaaa aggtcaggtc atttatcagc atcagattga aaagtcagat
    51421 gttgaggagt atatctcttg ggctaagcaa gaaggaattg agtatggctt ggttgggagt
    51481 catgatgcca agttgtcgac tcgcaccgat atgatgagtg aagctatcaa tccaatttat
    51541 cccgacttag atgtagatcc cgatttccat gaaaaagaag atatctatca gatgtggact
    51601 tttgaagata agggagatga cttgcacttg cctgatagtc tctcagacaa acttcgcatg
    51661 gttcgttggc atcaacattc gtctgatatt gtgccgattt caggctccaa agcgacgggg
    51721 gtggaaaagg ttgtggaaca ccttggcttg aaaccagaga aggtcatggt ttttggagat
    51781 ggtctcaacg acttggaact ctttgattat gctggaatca gcgttgctat gggaatttct
    51841 catgataaaa tcaaagaaaa agcagattat attacaaaaa cattagaaga agatggcatt
    51901 tttgatgcct tagaagtatt tggtatggta gaaaaagaat tgcattttcc acaagtagac
    51961 attgaaacag tagaaggtcc tcttgcgact attaagacca atcacggaga cttacgtatc
    52021 aagcttttcc ctgaacatgc tcctaaaaca gtggctaact ttgtatctct ttcaaaagat
    52081 ggctactatg atggtgtcat tttccaccgt attatcaagg actttatgat ccaaggtgga
    52141 gacccaactg gaactggtat gggtggcgag tcaatctacg gcgaatcttt tgaggatgaa
    52201 ttctcagaag agctttacaa tatccgtggt gctctttcca tggcaaatgc tggtccaaat
    52261 accaacggca gccagttctt tatcgtgcaa aaccaacacc taccttattc taagaaagaa
    52321 attactcgtg gtggttggcc agaaccgatt gcagaaatct atgccaatca aggtgggaca
    52381 cctcacctag accgccgtca cacggttttt ggtcagttag ctgatgaagc atcttacgct
    52441 gtcttggatg ccattgctgc tgttgagaca ggagctatgg acaagccagt tgaagatgtt
    52501 gtaattgaaa ctattgaaat cgaggactaa gatgaaaatc ggtgataagc taaaggggcg
    52561 tattacaggg attcagccct acggtgcctt tgttgagtta gagacgggtg atacggggct
    52621 gattcacatt tcagaaattc ggacaggatt tattgaaaat attcatgaaa ccttgaaagt
    52681 cgatgaagag gttcaagttc aggtagtgga tttagatgaa tttacgggga aagccagtct
    52741 ttctatccgc actttggagg aagaaaagta ccagtttcct agacggagac gcttttcaag
    52801 cgaccgcttt aactacggtt ttgctccctt tcgacgaatg ctaccaatct ggactggaga
    52861 agccctgcac catttaaaaa agaagaagta gtttagagtt ttatattttt tgtaatgtta
    52921 atataaattt gctataatag gaccatggaa gaagaacaat tattaaaatc aggagagcgc
    52981 attaaccagc tcttttcgac agatatcaaa atcattcaaa atagagaggt ttttagctat
    53041 tcggtggata gtgttctctt atcacgattt ccacgttttc ctaagaaggg gttgattgtg
    53101 gatttctgtg ctgggaatgg agcagtgggg ctttttgcta gcactcgtac tcaagcacag
    53161 atattgtctg ttgagattca ggagcgtttg gcggatatgg ctgaacgctc tgtccgtttg
    53221 aatggattag aggagcaaat gcaggtcatc tgcgatgatt tgaaaaatat gcctgctcac
    53281 attcagggga gtaaggtgga tatgattttg tgtaatccac cctatttcaa ggtggatcct
    53341 tattctaatc tgaacgagag tgaacattat ctcttggctc gacacgaaat cacgactaat
    53401 ttggaagaaa tctgtcgtag tgcccagagt attctcaagt ctaatgggcg tttggccatg
    53461 gttcatcgtc ctgatcgact tctggatatt ttggatacgt taaaacgaca taatctagcc
    53521 cctaagcgcc tgcagtttgt ttatccaaaa agagaaaagg aagccaatat gcttttgatt
    53581 gaggcgatca aggatggctc aacaagtggc tttaaggtct tacctccttt gattgtccac
    53641 aatgatgatg gctcttatac gcccgaaatc gaagagattt attatggatc ataaggctta
    53701 tatgtacgtt ctggagtgtc gtgatggatc ctactatata ggctatacga ctgatgtgag
    53761 aagacgcctc gctatccaca atagtgggaa gggagccaaa tatacacgag cacgcttgcc
    53821 agtcaaactt atctatgctc aaggttttgc cagtaaggaa gaagccatgt cggctgaagc
    53881 tcttctcaag cgtaagaaga ggccacagaa ggaagaattt ttatctgaaa atcaagatag
    53941 aaatttactc agttattttg aagaatcgtg gggagtcctt tgactcctct tacctttgtc
    54001 aaaaagcgaa aaaaatgcta caataaagaa aataaacaaa atgaggtatt atcatgtcca
    54061 agattctagt atttggtcac caaaatccag actcagatgc catcgggtca tctgtagctt
    54121 ttgcctacct tgcaaaagaa gcttacggtt tggatacgga agctgttgcc cttggaactc
    54181 caaatgaaga aacagccttt gtcttgaact attttggtgt ggaagcacca cgtgttatca
    54241 cttctgccaa agcagagggg gcagagcaag ttatcttgac tgaccacaat gaattccaac
    54301 aatctgtatc agatatcgct gaagtagaag tttatggtgt tgtagaccac caccgtgtgg
    54361 ctaactttga aactgcaagc ccactttaca tgcgtttgga gccagttgga tcagcgtctt
    54421 caatcgttta ccgtatgttc aaagaacatg gtgtagctgt gcctaaagag attgcaggtt
    54481 tgatgctttc aggtttgatt tcagataccc ttcttttgaa atcaccaaca acacacccaa
    54541 cagataaaat cattgctcct gaattggctg aattggctgg tgtgaacttg gaagaatatg
    54601 gtttagcaat gttgaaagct ggtaccaact tggctagcaa atctgctgaa gaattgattg
    54661 acatcgatgc taagactttt gaactcaacg gaaataatgt ccgtgttgcc caagtgaaca
    54721 cagttgacat cgctgaagtt ttggaacgcc aagcagaaat tgaagctgca atgcaagctg
    54781 ccaacgaatc aaacggctac tctgactttg tcttgatgat tacagatatc gtcaactcaa
    54841 actcagaaat cttggctctt ggtgccaata tggacaaggt cgaagcggct ttcaacttca
    54901 aacttgaaaa caatcatgcc ttccttgctg gtgccgtttc acgtaagaaa caagtggtac
    54961 ctcaattaac tgaaagcttt aatgcgtaag attttgggtg tcagctcaaa atcggaaagt
    55021 ctagtttgcc ttatatcgaa aggagtttcg gctccttttt ttctaggagt gaagtatgtt
    55081 agaaaatggc gatttgattt ttgtgagaga tgggtcagac atgggacagg ccatccagac
    55141 ttccacaggt aactatagcc atgttgccat ttatttggat gggatgattt atcatgctag
    55201 tggacaggct ggtgttgtct gtcaagaacc ggcagacttc tttgagtcca atcatttgta
    55261 cgacctctat gtttatccag aaatggatat ccagtcggtg aaggaaagag cttgcagaca
    55321 tcttggagca ccctacaatg cttctttcta tccagatgca gctggtttct actgctccca
    55381 gtatatagca gaaatcctac ctatttttga aactattcct atgaaatttg gagatggaga
    55441 acaggagatt agtgattttt ggagggagta ttacatagaa ctaggtctgc ctgttcctct
    55501 gaaccaagct gggaccaatc ctagtcagtt ggcagcatcg cctctgttac aatgtaaaga
    55561 aaggaatctt catgattcag atttttaatc catctcgttt gacgagacag ccatttttgg
    55621 agaattgaac cgctatctgg accagtatga ggatgtgatt ctacgggaaa ttaaggctca
    55681 atttccagat attgcagttg ataaactcat ggaagagtat ataaaggcag gcttgattct
    55741 acgtgaaaat aagcgctatt acctcaattt tcctacgctt gaatcacttg atagtcttga
    55801 actggatcaa gagatttttg tcagagaagc tagtccggtc tatcaagcct tgttggagca
    55861 gagttttgag acggaattgc gcaatcaaat caatgcagct attttagttg aaaagacgga
    55921 ctttgcgcgc attaaaatga ccctgtccaa ttatttttac aaggtcaaac agcagtatcc
    55981 tttgacagaa aaacagcagg agctctatga cattttagga gatgttaatc ctgagtatgt
    56041 cctcaagtat atgacggctt ttttgttgaa atttctcaaa aaagaccagc ttatgcagaa
    56101 atgccgtgat atctttgtgg acagtttggt tgtcttaggc tatattgtgc aaaatgaaga
    56161 tggaaagtat gagttggcta tcgattttga taaggagaga ttaactttct acttagcgtg
    56221 atttcttgtt tctgagcaca ttgtttgact ttccttagta ttcggtataa actatatgta
    56281 accggtaaca catatcggaa taaactaaag gatacaatca tatgtcactt gaaaacaaat
    56341 tggaacaagc aacaggcgct gtcaaagaag gttttggtaa agttactgga gacagcaaga
    56401 cagaacttga aggagctgtt gaaaaaacag ttgctaaggc aaaagacgtt gtagaaaacg
    56461 caaaaggtgc tgtagaaggt gccgttgaag gtttgaaaaa cgtttttact aaagaatagg
    56521 aaaaaatcaa gggtttcatt ttcccttgat tttttctatt cttataaata attttctgcg
    56581 acggctgtat ctcctgggta ggattctttc ttgccctgga tgatttggta acaatcggct
    56641 cccttacccg caataataac tgcatctaat tcgtgatttg tgatagccat tgccgccttg
    56701 atggcttctt ggcgatccgc aatcttttca acaggatgat tgatgtagct actaatttca
    56761 tctgcaatgg ccattgggtc ttcatagtta gggtcatcag cagtcagaaa gacttgaatc
    56821 tcagggtgtt gattgaggag gaggccaaag tccttacgac gactttctcc cttgtttcct
    56881 gttgatccca gaaccagagc aatctttccg gtttgatgag tttcaaccac attgatgagt
    56941 tttttcagac tatccccatt gtgggcatag tcgatgaaga ccttggctcc atttttctga
    57001 gtgaggactt ccatacgacc aggaacgcgg gttgcagcga tgcctttttt gatgtcctca
    57061 agacttgctc cgagacggag acaagcaagt ccagcagcaa ctgcattttc ttggttgaag
    57121 ttgccaatga gttggatatc ataatctcca gcgagtttac ccgtagctga aaagctaaag
    57181 gctttggaat tctcgatttg gttatcaaat tggctaccat agaaatcatg gttttgatct
    57241 tcaacctgtt ctttcaagac tgagaagtgg tccatgtcac tgttaatgat gactgctcgg
    57301 ctattttcca tcaagagacg cttgtggtag aaatagtctt caaagctagg gtgttcaatc
    57361 gggccgatat ggtcttggct gatatttagg aaaactccca catcaaaggt tagaccatag
    57421 acacgtttga ccagataggc ttgactggag acttccatga tgaggtgggt acggtcattt
    57481 tgcacagcct gattcatcat gtcaaagagg tcaatactct caggggttgt caacgctgac
    57541 ttaaagaaag tctcgccatc aagagttgtg ttcatggtcg acaacatagc aggtcgatgc
    57601 ccttgagata agatgttata ggcgaaatag gctgccgttg tcttaccctt agttcctgtg
    57661 aaggcgagaa ttttgagttt ctcttgtgga ttaccataga actccatggc aatcaaactc
    57721 atggctttct ttatatcgtt cacaatgatg acagggatac cgacttcgta gtccttttca
    57781 gctacatacc aagctaaacc ttgtgttata gcagaaagaa ggtattcttt tttaaaggca
    57841 gcgccttttg caaaaaaaag agtgtcttct gttacttttc ggctgtcgta gctgatgcta
    57901 tcaaaaacaa ctttgctgta gttgtagtgg taatgacctt ggtcaataat ttcgcgaaaa
    57961 aggccatctt tctttaaaat atctaatacg gtttcaatct taatcatact ttctattgta
    58021 aaccgaaagt cgcaaattta caagtaacaa ggaaaagttt ataatggaag ataaggagtt
    58081 tttcctagtt atcaaaattg aatgaggaat ctatgtcgca cgaaaacaat caccagcagg
    58141 cccagatgtt acgggggact gcttggctaa cggctagtaa ctttatcagt cgcctactcg
    58201 gggctgttta cattatccct tggtacatct ggatgggggc ttatgcagct aaggcaaatg
    58261 gtctctttac catgggttac aatatctatg cttggttctt gttggtttca acagcgggga
    58321 ttccagttgc ggtggccaag caagtttcca agtataatac catgcgagaa gaagagcata
    58381 gctttgccct gattcggagc ttcttaggct ttatgacagg actaggcctg gtttttgctt
    58441 tagtcttgta tgtctttgct ccttggctag cagacttgtc tggcgtgggc aaagacttga
    58501 tcccaatcat gcaaagcttg gcttggggag tcttgatttt cccgtctatg agtgttatcc
    58561 gaggattttt ccaagggatg aataacctca aaccctatgc catgagccaa attgctgagc
    58621 aggtcattcg tgttatctgg atgctcctag caacctttat cattatgaag ctcggttcag
    58681 gagattatct agcagccgtt acccaatcaa cctttgctgc ctttgtcggt atggtagcca
    58741 gttttgcagt cttgatttat ttccttgccc aagaaggttc actcaaaaga gtctttgaaa
    58801 caggagataa gattaacagt aagcgtctct tggttgatac cattaaggaa gccattcctt
    58861 ttatcctgac agggtctgcc atccagctct tccagatttt ggatcagctg acctttatca
    58921 atagtatgag ctggtttacc aactacagca atgaggactt ggttgtcatg ttttcttatt
    58981 tctcagccaa tcctaataaa atcacgatga ttttgatttc tgtaggggtt tcgattggga
    59041 gtgttggttt gccacttttg acggaaaact atgtcaaggg ggacttgaaa gcagcttctc
    59101 gtctcgttca ggacagtctc accctactct ttatgttctt gctaccagca acggttggag
    59161 tggttatggt aggagagcct ctttatacgg tcttctatgg taagccagat agtttggcta
    59221 tgagcttatt tgtctttgca gttttgcagt ctattatttt aggcttgtac atggtcttgt
    59281 ctccaatgct tcaggccatg ttccgcaacc gcaaggccgt tctctatttt atctatggtt
    59341 ctattgccaa gctagtcttg caactaccta ccatcgccct cttccacagt tatggtcctt
    59401 tgatttcaac aaccattgct ctcatcattc ctaacgtctt gatgtatcgg gatatttgta
    59461 aagtaactgg tgtcaagcgc aaggtgattt tgaagcgaac cattttaatc agtttgctga
    59521 ccctagtcat gtttctgtta ataggaacca tccagtggct gttaggattt ttcttccaac
    59581 caagtggacg tttgtggagc ttcttttatg tagctcttgt cggtgccatg gggggtggac
    59641 tttatatggt tatgagtctg cgtacctatt tgttagataa ggtaatagga aaagcccaag
    59701 cagatcgcct gcgagcaaaa tttaagcttt cgtaaggtag catttataaa taaaaggaat
    59761 aagttgaaca atctttta
//
LOCUS       DAVHSI010000010        58572 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.010, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000010 DAVHSI010000000
VERSION     DAVHSI010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58572
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.010"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            445..1920
                     /locus_tag="VVR21_000668"
     CDS             445..1920
                     /locus_tag="VVR21_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU6054590.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGSSHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(1886..2476)
                     /locus_tag="VVR21_000669"
     CDS             complement(1886..2476)
                     /locus_tag="VVR21_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6054591.1"
                     /translation="MSLRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYNPLLIK
                     KFAKSLLLRKTKTDKKDAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTCYPNPQKRIEAGFDKLIEIKRLTAS
                     NSRAFCRALKSSPNHQIEIRNSLDKTIDFSYSLSFS"
     gene            2856..3716
                     /gene="speE"
                     /locus_tag="VVR21_000670"
     CDS             2856..3716
                     /gene="speE"
                     /locus_tag="VVR21_000670"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU6054592.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            3713..4972
                     /locus_tag="VVR21_000671"
     CDS             3713..4972
                     /locus_tag="VVR21_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU6054593.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            4972..6099
                     /gene="nspC"
                     /locus_tag="VVR21_000672"
     CDS             4972..6099
                     /gene="nspC"
                     /locus_tag="VVR21_000672"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU6054594.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6096..7181
                     /gene="aguA"
                     /locus_tag="VVR21_000673"
     CDS             6096..7181
                     /gene="aguA"
                     /locus_tag="VVR21_000673"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU6054595.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7191..8066
                     /gene="aguB"
                     /locus_tag="VVR21_000674"
     CDS             7191..8066
                     /gene="aguB"
                     /locus_tag="VVR21_000674"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU6054596.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8247..9056)
                     /locus_tag="VVR21_000675"
     CDS             complement(8247..9056)
                     /locus_tag="VVR21_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6054597.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9328..9549
                     /locus_tag="VVR21_000676"
     CDS             9328..9549
                     /locus_tag="VVR21_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU6054598.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            9603..10274
                     /locus_tag="VVR21_000677"
     CDS             9603..10274
                     /locus_tag="VVR21_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6054599.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10326..10523)
                     /locus_tag="VVR21_000678"
     CDS             complement(10326..10523)
                     /locus_tag="VVR21_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054600.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            10516..11424
                     /locus_tag="VVR21_000679"
     CDS             10516..11424
                     /locus_tag="VVR21_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU6054601.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11421..11882
                     /locus_tag="VVR21_000680"
     CDS             11421..11882
                     /locus_tag="VVR21_000680"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU6054602.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAILKEEINGN"
     gene            11872..12759
                     /locus_tag="VVR21_000681"
     CDS             11872..12759
                     /locus_tag="VVR21_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6054603.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            12762..14645
                     /gene="cbpE"
                     /locus_tag="VVR21_000682"
                     /gene_synonym="pce"
     CDS             12762..14645
                     /gene="cbpE"
                     /locus_tag="VVR21_000682"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU6054604.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRHLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKEKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            14725..15855
                     /locus_tag="VVR21_000683"
     CDS             14725..15855
                     /locus_tag="VVR21_000683"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU6054605.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            15865..17127
                     /locus_tag="VVR21_000684"
     CDS             15865..17127
                     /locus_tag="VVR21_000684"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU6054606.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEILLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            17131..17928
                     /gene="proC"
                     /locus_tag="VVR21_000685"
     CDS             17131..17928
                     /gene="proC"
                     /locus_tag="VVR21_000685"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU6054607.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLSRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            18148..18786
                     /locus_tag="VVR21_000686"
     CDS             18148..18786
                     /locus_tag="VVR21_000686"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU6054608.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            18783..19673
                     /locus_tag="VVR21_000687"
     CDS             18783..19673
                     /locus_tag="VVR21_000687"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU6054609.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            19713..20030
                     /gene="yabA"
                     /locus_tag="VVR21_000688"
     CDS             19713..20030
                     /gene="yabA"
                     /locus_tag="VVR21_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU6054610.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            20033..20902
                     /gene="rsmI"
                     /locus_tag="VVR21_000689"
     CDS             20033..20902
                     /gene="rsmI"
                     /locus_tag="VVR21_000689"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU6054611.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            21129..21647
                     /locus_tag="VVR21_000690"
     CDS             21129..21647
                     /locus_tag="VVR21_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU6054612.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            21756..22403
                     /locus_tag="VVR21_000691"
     CDS             21756..22403
                     /locus_tag="VVR21_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6054613.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(22392..23195)
                     /locus_tag="VVR21_000692"
                     /pseudo
     CDS             complement(22392..23195)
                     /locus_tag="VVR21_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            23190..23444
                     /locus_tag="VVR21_000693"
     CDS             23190..23444
                     /locus_tag="VVR21_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6054614.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            23689..25023
                     /gene="trmFO"
                     /locus_tag="VVR21_000694"
     CDS             23689..25023
                     /gene="trmFO"
                     /locus_tag="VVR21_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU6054615.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            25107..25844
                     /locus_tag="VVR21_000695"
     CDS             25107..25844
                     /locus_tag="VVR21_000695"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU6054616.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRSAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            25853..26410
                     /gene="frr"
                     /locus_tag="VVR21_000696"
     CDS             25853..26410
                     /gene="frr"
                     /locus_tag="VVR21_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU6054617.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            26470..27324
                     /gene="cvfB"
                     /locus_tag="VVR21_000697"
     CDS             26470..27324
                     /gene="cvfB"
                     /locus_tag="VVR21_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU6054618.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPEFKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            27333..27548
                     /locus_tag="VVR21_000698"
     CDS             27333..27548
                     /locus_tag="VVR21_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU6054619.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            27634..28602
                     /locus_tag="VVR21_000699"
     CDS             27634..28602
                     /locus_tag="VVR21_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU6054620.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(28580..28759)
                     /locus_tag="VVR21_000700"
     CDS             complement(28580..28759)
                     /locus_tag="VVR21_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054621.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            28795..29295
                     /locus_tag="VVR21_000701"
     CDS             28795..29295
                     /locus_tag="VVR21_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054622.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            29298..29558
                     /locus_tag="VVR21_000702"
                     /pseudo
     CDS             29298..29558
                     /locus_tag="VVR21_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(29925..30251)
                     /locus_tag="VVR21_000703"
     CDS             complement(29925..30251)
                     /locus_tag="VVR21_000703"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054623.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTNLPVAQGLNRDYT
                     DINDLV"
     gene            complement(30197..30610)
                     /locus_tag="VVR21_000704"
     CDS             complement(30197..30610)
                     /locus_tag="VVR21_000704"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU6054624.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(30611..31036)
                     /locus_tag="VVR21_000705"
     CDS             complement(30611..31036)
                     /locus_tag="VVR21_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU6054625.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            31213..31782
                     /locus_tag="VVR21_000706"
     CDS             31213..31782
                     /locus_tag="VVR21_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054626.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGKFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            31850..32500
                     /locus_tag="VVR21_000707"
     CDS             31850..32500
                     /locus_tag="VVR21_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU6054627.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEEEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            32484..34724
                     /locus_tag="VVR21_000708"
     CDS             32484..34724
                     /locus_tag="VVR21_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU6054628.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMSELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGKGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPRE
                     IGYGGHEDSLVLYGKLLNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            34866..35090
                     /locus_tag="VVR21_000709"
     CDS             34866..35090
                     /locus_tag="VVR21_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054629.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYDSYSEYPVGSGWNYGRYEVINYYSGGY"
     gene            35122..35709
                     /locus_tag="VVR21_000710"
     CDS             35122..35709
                     /locus_tag="VVR21_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054630.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            35713..36897
                     /locus_tag="VVR21_000711"
     CDS             35713..36897
                     /locus_tag="VVR21_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054631.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTAISGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIIFLLVGILFIENWGSSRKKEVFN
                     RS"
     misc_feature    37052..37183
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            37199..37729
                     /gene="infC"
                     /locus_tag="VVR21_000712"
     CDS             37199..37729
                     /gene="infC"
                     /locus_tag="VVR21_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU6054632.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            37762..37962
                     /gene="rpmI"
                     /locus_tag="VVR21_000713"
     CDS             37762..37962
                     /gene="rpmI"
                     /locus_tag="VVR21_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU6054633.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            38014..38373
                     /gene="rplT"
                     /locus_tag="VVR21_000714"
     CDS             38014..38373
                     /gene="rplT"
                     /locus_tag="VVR21_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU6054634.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            38431..38811
                     /locus_tag="VVR21_000715"
     CDS             38431..38811
                     /locus_tag="VVR21_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU6054635.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            39061..39861
                     /locus_tag="VVR21_000716"
     CDS             39061..39861
                     /locus_tag="VVR21_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU6054636.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            39824..40810
                     /locus_tag="VVR21_000717"
     CDS             39824..40810
                     /locus_tag="VVR21_000717"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU6054637.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            40852..43017
                     /gene="lytB"
                     /locus_tag="VVR21_000718"
     CDS             40852..43017
                     /gene="lytB"
                     /locus_tag="VVR21_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEU6054638.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFHLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(43078..44733)
                     /gene="pavA"
                     /locus_tag="VVR21_000719"
     CDS             complement(43078..44733)
                     /gene="pavA"
                     /locus_tag="VVR21_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU6054639.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            44838..45335
                     /gene="ybeY"
                     /locus_tag="VVR21_000720"
     CDS             44838..45335
                     /gene="ybeY"
                     /locus_tag="VVR21_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU6054640.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            45316..45711
                     /locus_tag="VVR21_000721"
     CDS             45316..45711
                     /locus_tag="VVR21_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU6054641.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            45728..46627
                     /gene="era"
                     /locus_tag="VVR21_000722"
     CDS             45728..46627
                     /gene="era"
                     /locus_tag="VVR21_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU6054642.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            46676..47500
                     /gene="mutM"
                     /locus_tag="VVR21_000723"
     CDS             46676..47500
                     /gene="mutM"
                     /locus_tag="VVR21_000723"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU6054643.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQSLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            47500..48105
                     /locus_tag="VVR21_000724"
     CDS             47500..48105
                     /locus_tag="VVR21_000724"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU6054644.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            48092..49291
                     /locus_tag="VVR21_000725"
     CDS             48092..49291
                     /locus_tag="VVR21_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU6054645.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            49291..49440
                     /gene="rpmG"
                     /locus_tag="VVR21_000726"
     CDS             49291..49440
                     /gene="rpmG"
                     /locus_tag="VVR21_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6054646.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            49480..49713
                     /gene="secG"
                     /locus_tag="VVR21_000727"
     CDS             49480..49713
                     /gene="secG"
                     /locus_tag="VVR21_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU6054647.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            49815..52169
                     /gene="rnr"
                     /locus_tag="VVR21_000728"
     CDS             49815..52169
                     /gene="rnr"
                     /locus_tag="VVR21_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU6054648.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQGKPKYVGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEVSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            52132..52599
                     /gene="smpB"
                     /locus_tag="VVR21_000729"
     CDS             52132..52599
                     /gene="smpB"
                     /locus_tag="VVR21_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU6054649.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLYKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            52615..53475
                     /gene="tehB"
                     /locus_tag="VVR21_000730"
     CDS             52615..53475
                     /gene="tehB"
                     /locus_tag="VVR21_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU6054650.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGAIK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            53548..54501
                     /gene="coiA"
                     /locus_tag="VVR21_000731"
     CDS             53548..54501
                     /gene="coiA"
                     /locus_tag="VVR21_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU6054651.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     DLEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTNYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVK"
     gene            54520..56322
                     /gene="pepF"
                     /locus_tag="VVR21_000732"
     CDS             54520..56322
                     /gene="pepF"
                     /locus_tag="VVR21_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6054652.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            56324..57037
                     /locus_tag="VVR21_000733"
     CDS             56324..57037
                     /locus_tag="VVR21_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU6054653.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKKVADVQLSESE"
     gene            57104..58045
                     /gene="prsA"
                     /locus_tag="VVR21_000734"
     CDS             57104..58045
                     /gene="prsA"
                     /locus_tag="VVR21_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU6054654.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(58162..58503)
                     /locus_tag="VVR21_000735"
                     /pseudo
     CDS             complement(58162..58503)
                     /locus_tag="VVR21_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        17608 a        10730 c        13252 g        16982 t
ORIGIN      
        1 ttttttatca aaaaatactt tacaagttct taaaaacatg atatagtaat aaagcttaga
       61 aaatgagatg atgttttcta gcaaatataa acccgagtaa aaaatgccta cggacaggca
      121 gggttgaatg ccgaagcgtg gttgaaaagc cacattattg atagggttaa aagcctactt
      181 ttataagttg atgttaggac acttgttcta attcataaat ttttagtgtg gtgaaagcac
      241 acgtcatctt gtgaaacgat caataaagta cgtaatattt gctactagag agttaggaaa
      301 catcgggaac agacatactc aacagaaacc aaaataaaca cgtcagaaga ttgcagagca
      361 ggtgaaaacc tgctcttttt tcatgagtca acctttagtt ccttagtttt cataaggtcc
      421 taaaaatatt gaaaggagta tgttttgaaa gagttagatc aaaaccaagc cccaatttat
      481 gaggccttgg tgaagttacg caagaaaagg attgttccct ttgatgttcc aggtcacaag
      541 cgtggacggg gaaatccaga acttgtcgaa ctcttaggag aaaaatgtgt aggcattgat
      601 gtcaattcga tgaaaccctt ggataattta ggccatccta tttcgattat tcgtgatgca
      661 gaggagctgg ctgcagatgc ttttggatct agccatgcct ttctaatgat tggtggaaca
      721 acttcatcgg tgcagactat gattctggca acctgcaagg caggagataa gattattctg
      781 ccacgaaatg tccataaatc tgctatcaat gcgttggttc tatgtggtgc cattcccatc
      841 tatatcgaga tgagtgtaga tcctaagatt ggtatcgctt taggtcttga aaatgaccga
      901 gtagcacagg ccataaagga ccatccagat gctaaggcta tcctaatcaa caatcctact
      961 tactacggca tctgttcaga cctaaagggg ttgacagaaa tggctcatga agctggcatg
     1021 atggttttag tagatgaagc ccacggagcg catttgcatt tcactggtaa acttccaatt
     1081 tctgctatgg atgcaggagc tgatatggca gcagtttcca tgcataagtc tggtgggagt
     1141 ttgacacaaa gttcgcttct tttaatcggg gagcagatga atcccgagta cgttcgtcag
     1201 attataaacc tgacccagtc tacatctgcc tcttacttat tgatggctag tttggatatt
     1261 tcacgtcgca acttggccct tcgtggtaaa gagtcgtttg aggaagtcat tgagctatcc
     1321 gagtacgctc gtcatgaaat caatgccatt ggcggttact atgcttactc aaaagagtta
     1381 atagatggtg tgtcggtctg tgattttgat gtaaccaagt tgtcagttta cactcaggga
     1441 ataggcttaa caggtatcga ggtttatgac ctcttgcgag acgaatacga cattcagatc
     1501 gagtttggtg atatcggcaa tatcttggcc tatatttcca tcggcgaccg catccaagac
     1561 atcgagcgct tggttggtgc tctggctgat attaagagac tctattcacg agatgggaag
     1621 gacttaatag ctggagaata tattcagccc gagttggtgc tgtctccaca agaagccttc
     1681 tattcagaga gaaaaagttt gaccttagat gagtctgttg gacaggtctg tggagaattt
     1741 gtcatgtgct atcctccagg gattcctatc ttggctcctg gtgaacgcat tacacgagaa
     1801 attgtagact atatccaatt cgccaaggaa cgtggttgct ccctccaagg gacggaagat
     1861 ccagaggtca atcatatcaa cgttattaag agaaagacaa actataagaa aagtcaatag
     1921 ttttatctaa actatttctt atttcaattt gatgatttgg cgatgatttt agagcacggc
     1981 aaaaagccct tgaattagaa gcggtcaatc gcttaatttc tatcagctta tcaaatcctg
     2041 cctcaatcct tttctgagga ttagggtagc atgtcaagag ttggtaggta tattctgaat
     2101 gctttccaac gattttatcc aactcaggaa agatgatatc aagacaacga gtgtattgca
     2161 ctttccaatc agactgtttt ttcttgagac gatgaatatg tctagccagt atttttagtt
     2221 ctacttgccg attatcgtgt tgaaattgtt cacgattggg atcagaaaga agtttaagag
     2281 cgatgccatg agcgtctttc ttatccgttt tagtcttgcg aagtaataat gatttggcaa
     2341 atttcttgat gagcaaagga ttgtaggtgt aaactttata tccttgttca tgcaggaagt
     2401 tcagtagatt aaaggcataa tgtccagtat cttcaagagc gatgagacag tcttggttga
     2461 gctgtcgaag agacagatct aagagttcaa aaccagcttt attatttgaa aaagtgagtg
     2521 gtttaagaac agttttcctg gaacattcaa ggctgtaaca tcgtgtttat ttttagcgac
     2581 atcaatgccc acataaagca tgggagtacc tccagatata gtatttcaag tctacttggt
     2641 tatccacgaa ctttttgcct tgttacctta gacgagataa aacgtctatg cgttatcaaa
     2701 ctcattacca attgaaacaa aagctgtggt tagagccttt cggaaatcgt caagcgattg
     2761 gagggaataa actaatccac agtggcttat tccaagtata ccacttgggc tttggcagta
     2821 gctaactgcg ctaaatataa tataaggaga aatagatgga tttatggttt tctgaagttc
     2881 atactccaga tgtcaaattg tctctgagaa cagccaagca actttacgct ggaaaaagtg
     2941 aatggcagga tatcgaagtc ttggatacgc cagcttttgg gaaaatactg attttaaatg
     3001 gccatgtctt gttctcagat gcggatgatt tcgtctacaa tgaaatgacc gttcacgttc
     3061 ccatggctgt ccacccaaat ccaaagaaag tattggttat tgggggtggt gacggcggtg
     3121 ttgcccaagt attaacactc tatcctgaac tggaacaaat cgatatcgtg gaaccggatg
     3181 agatgttggt cgaggtctgt cgtgagtatt tcccagactt tgctgcaggg ctagatgatc
     3241 ctcgtgttac catttactac caaaatgggc tacgcttttt gcgaaactgc gaagatgatt
     3301 acgatattat catcaacgat gcgacagatc catttggcca tacggaagga ctctttacca
     3361 aggaattcta cggcaatagt tatcgagctc tgaaggaaga cggcatcatg atttaccagc
     3421 atgggagtcc cttctttgac gaggatgagt cggcctgccg aagcatgcac cgcaaggtca
     3481 atcaatcctt tccaatcagt cgggtttatc aggcccatat tccaactagc ccagctggct
     3541 attggttgtt tggatttgca tcgaaaaaat accaccctgt caaagatttt gacaaggaag
     3601 gttggaaaaa acgccagctt ttcacagaat actacactgc aaacttacac gtgggatcct
     3661 ttatgttgcc caagtatgtt gaggacattt tagaagaaga ggaaggaaaa aaatgagtcg
     3721 tttactagtt attggttgtg ggggcgttgc ccaagttgct atttcaaaga tttgtcaaga
     3781 tagcgaaaca tttacagaga ttatgattgc tagccgtacc aagtcaaaat gcgatgactt
     3841 gaaagcgaag ctagaaggca aaacaagtac taaaattgaa actgcagcac ttgatgctga
     3901 caaggttgaa gaagtgattg ccctgattga aagctacaaa ccagaagctg ttttgaatgt
     3961 agctctgcct tatcaagatt taaccattat ggatgcttgt ttggcaacag gtgttcacta
     4021 tatcgataca gccaactacg aagcagaaga cacagaagac cctgagtggc gtgctatcta
     4081 cgaaaaacgt tgtaaggaac ttggttttac agcctacttt gactactcat ggcagtgggc
     4141 ttatcaagag aaattcaaag aagcaggctt gactgctctt cttggttctg gttttgaccc
     4201 aggtgtaact agtgtctttt cagcttatgc cctcaaacac tattttgatg aaatccatta
     4261 tatcgacatt ttagactgta atggcggtga ccacggttat ccatttgcaa ccaactttaa
     4321 tccagaaatt aatctccgtg aggtttctgc gccaggttct tactgggaag atgggaaatg
     4381 ggtcgaagtc gaagctatgt ctatcaagcg tgagtatgat ttccctcaag ttggacaaaa
     4441 agatatgtat ctccttcacc atgaagaaat cgaatcattg gccaagaaca ttccaggtgt
     4501 caaacgcatt cgtttcttta tgacttttgg tcaatcttac ttgacgcaca tgaaatgtct
     4561 tgaaaatgtt ggactccttc gtacggatac cattaacttt aacggccaag aaattgttcc
     4621 aattcaattt ttgaaagcct tgcttccaga tcctgccagt cttgggccac gtacagtcgg
     4681 aaaaaccaat attggatgta tctttacagg tgtcaaagac ggtgtcaaaa agactatcta
     4741 tatctacaat gtctgcgacc atcaggaatg ttacgcagag gttggttcgc aagctatttc
     4801 ttatacgaca ggagttccag ccatgattgg gacaaaatta gtcatgaacg gaacttggaa
     4861 acaagctgga gtgtataacc ttgaggagtt agatccagat ccattcatgg aagctttgaa
     4921 tgagtatggt ttgccatggg ttgtggttga aaatccacaa atggtggact aatgaagtta
     4981 gaacaagtac caacaccagc ctatgttatt gacttggcca agttagaagc taattgccgc
     5041 attctacaat atgtacaaga agaggtcggt tgcaaggtct tgcttgccca gaaggcatat
     5101 tccctctaca aaacttatcc cttgattagc cagtatctat caggtacgac agctagtgga
     5161 ctctatgagg ccaaattggc aagggaagaa tttcctggtg aagtccatgt atttgcgcct
     5221 gctttcaagg atgcagactt ggaggaattg cttgggataa cagaccatat cgtctttaac
     5281 tcagagagac agttgcgtaa gcatggggct cgttgtcgag aggctggtgt cagtgttggt
     5341 ttgcgcctca accctcagtg ttcaactcaa ggagatcacg cgctctatga cccttgtgca
     5401 ccaggttctc gctttggagt tactatagac aagattccga gtgatttgct agatttggtt
     5461 gacggacttc attttcatac cctttgcgag cagggagcag atgatttaca aacaactttg
     5521 aaagcagtag aagaacagtt tggtccctac ttacatgagg taaaatggct caatatgggt
     5581 ggtggtcatc atattacaag agaaggttac gatgtggatt tgctgatttc agaaatcaag
     5641 cgtatccgaa aaacttacaa tcttgaaata tatatcgagc ctggtgaagc cattgcgctt
     5701 aatgcgggtt atttagcaac tgaggtatta gatattgtag aaaacggtat ggaaatcttg
     5761 gttttagacg cctctgcgac ctgccatatg cctgatgtac ttgagatgcc ctatcgtcca
     5821 cctttgagaa atggctttga ggcacaggaa aaagcccata cctacagact ttcttctaat
     5881 acttgtctga ctggcgatgt gattggtgat tatagttttg aaaatccagt ccaaatcgga
     5941 gacagacttt attttcaaga catggccatt tattcttttg tcaaaaataa tacctttaat
     6001 ggtattggat taccaagtct ctatctcatg gacgaacagg gagactgtag cttactcaaa
     6061 gcttttggct atcaagactt taaagggaga ttatcatgat ggacagtcca aaaaaattag
     6121 gctatcacat gccagcagag tacgaacccc atcatggtac cctcatgata tggccgactc
     6181 gaccaggatc atggcctttt caaggaaagg ctgctaaaag agcatttact cagatcatcg
     6241 agaccatagc agaaggggaa agagtctatc ttttggtgga gcaggcctat ctatctgaag
     6301 cccaatccta tcttggagac aaggttgttt atttagacat tcccaccaat gatgcctggg
     6361 cgcgtgatac tggcccaacc attctcgtca atgataaagg taagaaatta gccgtggatt
     6421 gggcctttaa tgcttgggga ggcacctatg atggtcttta tcaagattat gaagaggatg
     6481 accaagtagc cagtcgtttt gctgaggcct tggaaaggcc tgtctatgat gctaaacctt
     6541 ttgtactgga aggaggcgca atccatagcg atggtcaagg aactattctc gtaactgaaa
     6601 gttgcttgct tagtcctggt cgcaatccta acctgactaa agaggagatt gaaaacacat
     6661 tattagaaag tcttggtgct gaaaaagtta tttggcttcc ttatggtatt tatcaggatg
     6721 aaaccaatga acacgtcgat aatgttgctg cctttgttgg tcctgctgag cttgttttgg
     6781 cttggacaga tgacgaaaat gatccccagt atgccatgtc aaaagcagat ctcgaactct
     6841 tagaacagga aacagatgca aaaggttgtc acttcaccat tcataaattg cctatccctg
     6901 cagttcgaca agttgtgaca gaagaagatt tgccaggcta catctatgaa gaaggagaag
     6961 aaaagcgata cgcaggtgaa cgactagcag cttcctacgt aaacttttat atcgccaaca
     7021 aggctgtctt ggttccacag tttgaggatg taaacgacca agtggcctta gatatcctca
     7081 gcaagtgttt cccagaccgt aaagttgtcg gaataccagc cagagatatt ctcttaggtg
     7141 gtggcaatat ccactgtatc acccaacaaa ttccagaata ggagaaaaag atgagaaatg
     7201 taagagttgc aaccattcag atgcaatgcg ctaaggatgt ggcaacaaat atccaaaccg
     7261 cagagcgttt agtacgtcag gctgctgagc aaggagccca aattattctc ttgcccgagt
     7321 tgtttgaaca tccctatttc tgtcaggaac gtcagtatga ctactaccag tatgcccaat
     7381 ctgtagcgga aaatactgcc attcagcatt ttaaggtgat tgctaaggaa ctacaagttg
     7441 ttttaccaat cagtttctat gaaaaagatg gtaatgtctt gtataactct attgccgtca
     7501 ttgatgcaga tggggaagtg ctgggcgttt atcgaaagac ccatatacca gatgaccatt
     7561 attatcaaga aaaattctat ttcacgcctg gtaacactgg tttcaaggtc tggaatactc
     7621 gctatgctaa gattggtatc ggtatctgtt gggatcaatg gttccctgaa acagcgcgct
     7681 gtcttgcatt gaatggtgct gaattgctct tttatcctac agctatcggt tcagagccaa
     7741 ttttggatac agatagttgt ggtcactggc aacgtactat gcaagggcac gcagcagcga
     7801 atattgttcc agtcatcgca gccaatcgtt atggtttaga ggaggttact cctagtgagg
     7861 aaaatggcgg acagagttcc agtcttgact tctacggttc ctcctttatg acggatgaaa
     7921 caggagctat tctagaacga gctgaaagac aagaagaagc tgttctgtta gctacttatg
     7981 acctagacaa gggagcaagt gaacgcctaa actggggctt gtttcgagat agaagaccag
     8041 aaatgtatag acaaattaca gattagtgtg ggagaaatga gagattcatt ctgctagact
     8101 aacttcttat tagcaactat aagatactat ggcatctagt aaatcgattt ttatgattcg
     8161 ctattcttgt ctattgatta gtccgtattt taaaatatta gcaaaaaagc aaatagcagt
     8221 aacttctgtc tatttgcttt tcttttttat agaatatatt tctcaatagc acgcgcaacg
     8281 ccgtcttctt cgttgcttga tgtaacggca tccgcaagag atttgacata atcgctggca
     8341 tttcccattg caatcccaag ccctgcaaac tggagcattt cgatatcgtt attagcatcg
     8401 cccatggcca taatctctga ggaatcaatc ttcaaaatct cagctagtcg tgaaagagca
     8461 gtagcctttg tcgttccaag cggcattgct tcataaatga caggctgcga acgaactcca
     8521 ctgaatcgtt ggcaaagctc ttcagcaaaa cgctgctcaa aatcgtctgt ttgttctttt
     8581 gttcctaaaa acataccttg gaacatccgg aactttccac tagtcgcttc ttcaagagaa
     8641 atttcagtca ggtctgaaaa tactagttta gcatcatttt caataacttg attgggtttg
     8701 ccaccgagaa caaaataatg tgactcgtca aaaagtgtca actgaacatc actcttttca
     8761 gcaaggtcat agaggtattc gatgtcagct ggactcagtt cttgccagtc aaccaagccc
     8821 cagtcgctag tctggtgagt tgaacaaccg ttgttaacaa taatatattc gttctggagg
     8881 tcaagctcca gttttttgta gtaggggagg acaccgaaaa gggggcgacc cgtacagaga
     8941 accagtttga cacctttttc aatggctttg tgaatagcag taatgtgagc ttgtgggatt
     9001 tccttggctt cattgaggag ggtgccgtcc atatccaagg ctagtagttt aatcataggt
     9061 cttccttctt tatcttttgc tattattata gcatattttg gagaagaaat tgatagaaag
     9121 cttgagacta attgatttta tagtttaaga tgttttgatg acaattcatg atttgaagag
     9181 gatatttcgc aaagatatgc tatactatgt ttgtcaatgt tgcaactaga caaattaaaa
     9241 aaccaactta atataatagt ttttttgtaa gtaggtatga gtatcagatt actcaactaa
     9301 tctgaagaat aatggaggaa atatatcatg attttaatga caaaaaatat aaatctaaca
     9361 aatgaagaat tagagctgat acaaggtgga gcagattcat atggtaaaaa tcctaatggt
     9421 aggtacgatt gggaaataga accagtatta actctgccgg ttcatggatt ttgtcccaga
     9481 ggcacctatg atttaggata tattggagga ggcaatcatc tttgcaaagg aagtgctgcg
     9541 agattttaag taaaatttat tagtaatatg aagaaacaag gggagaaagc agagaattta
     9601 atatgaaaaa acgggctatt caaattttac tagcattgtc cttaattttt tacaaatcaa
     9661 cttggttttg gagagttttc aatcacctcg caaagcccta tctaccagca agtcgtgaat
     9721 tttttcagat tctgcttttg atggagagcg gagttctttt cttagcggtc atctatctac
     9781 tggtttttgc aggaaagaaa atttttcatt tcaagtggca gctgaggtac ttcatctacc
     9841 ttttactggg ctacatcatt tcatatatgt ctgacttcct cttttcgtat ttcatatccc
     9901 tgtcttcaaa tcagatttct ttgaatgaaa cggtagaaat gatggggaga caggagttcc
     9961 cttatttctt gctcatcgtt tgcttcatcg cccctattgc tgaggaattg atttatcgag
    10021 gtgtgcttat gacaaccttt ttcaaaaact caccttggta cggagatgtt ttgctttctg
    10081 ctattatttt cggttatatt catatcaatt ttgctttaac tcctcttgct tttttcattt
    10141 atgctagtgg aggtcttatt ttagctctat tgtatcgcat gactaaaaat ctctactatc
    10201 caatactagt tcatattctc atcaatatca ctgccttctg ggatgtttgg ttactcctat
    10261 tttcaggaag ttagcttact aaaaaaatgt cggaattttc cggcattttc ttttttcaca
    10321 aatagtcaac gtttttcttt ccgatactga agtggtgtgt agccacttat ttttttgaat
    10381 tgattttgaa aataagattg gcgtgagaaa ggcagatagt gaagatagtt aagaagaata
    10441 ggatgttctt ttttcctttt tggaaaactt ctaaaatatg gtataatgaa aagataaaga
    10501 agttgggggt agaagatgaa cattcaacaa ttacgctatg ttgtggctat tgccaatagt
    10561 ggtacttttc gtgaagctgc tgaaaagatg tatgttagtc agccgagtct gtctatttct
    10621 gttcgtgatt tggaaaaaga gttgggcttt aagattttcc gtcggaccag ctcagggact
    10681 ttcttgaccc gtcgtgggat ggaattttat gaaaaagcgc aagaattggt taaaggattt
    10741 gatatttttc aaaatcagta tgccaatcct gaagaagaaa aagatgaatt ttccgttgct
    10801 agccagcact atgacttctt accaccaact attacggcct tttcagagcg ctatcctgac
    10861 tataagaact tccgtatttt tgaatcaact actgttcaaa tattagatga agtggcgcaa
    10921 gggcatagtg agattgggat tatctacctc aacaatcaaa ataaaaaggg gattatgcaa
    10981 cgggttgaaa agttaggtct ggaggtcatc gaattgattc ctttccatac ccatatttat
    11041 ctctgtgagg gtcatccttt agcccagaaa gaggaattag tcatggagga tttagcggat
    11101 ttaccaacgg ttcgtttcac tcaagagaaa gacgagtacc tttattattc agagaacttt
    11161 gttgatacca gcgctagctc acagatgttt aatgtgacag accgtgccac cttgaatggt
    11221 attttggagc ggacggacgc ctatgcgaca ggttctggat ttttagatag tgacagtgtt
    11281 aatggcatta cagttattcg tctcaaggat aacctagata accgcatggt ctatgttaaa
    11341 cgtgaagaag tggagcttag tcaagctggg actctcttcg tagaagtcat gcaagaatat
    11401 tttgatcaaa agaggaaatc atgaaaaaaa gagcaatagt ggcagtcatt gtactgcttt
    11461 tgattgggct ggatcagttg gtcaaatcct atatcgtcca gcagattcca ctgggtgaag
    11521 tgcgctcctg gatccccaat ttcgttagct tgacctacct gcaaaatcga ggtgcagcct
    11581 tttctatctt acaagatcag cagttgttat tcgccgtcat tactctggtt gtcgtgatag
    11641 gtgccatttg gtatttacat aaacacatgg aggactcatt ctggatggtc ttgggtttga
    11701 ctctaataat cgcgggtggt cttggaaact ttattgacag ggtcagtcag ggctttgttg
    11761 tggatatgtt ccaccttgac tttatcaact ttgcaatttt caatgtggca gatagctatc
    11821 tgacggttgg agtgattatt ttattgattg caatactaaa agaggaaata aatggaaatt
    11881 aaaattgaaa ctggtggtct gcgtttggat aaggctttgt cagatttgtc agaattatca
    11941 cgtagtctcg cgaatgaaca aattaaatca ggccaggtct tggtcaatgg tcaagtcaag
    12001 aaagctaaat acacagtcca agagggtgat gtcgtcactt accatgtgcc agaaccagag
    12061 gtattagagt atgtggctga ggatcttccg ctagaaatag tctaccaaga tgaggatgtg
    12121 gctgtcgtta acaaacctca gggaatggtt gtgcacccga gtgctggtca taccagtgga
    12181 accctagtaa atgccctcat gtatcatatt aaggacttgt cgggtatcaa tggggttctg
    12241 cgtccaggga ttgttcaccg tattgataag gatacgtcag gtcttctcat gattgctaaa
    12301 aacgatgatg cgcatctagc acttgcccaa gaactcaagg ataaaaagtc tctccgcaaa
    12361 tattgggcga ttgttcatgg aaatctgcct aatgatcgtg gtgtaattga agcgccgatt
    12421 ggccggagtg aaaaagaccg taagaaacag gctgtaactg ctaaagggaa gcctgcagtg
    12481 acgcgttttc acgtcttgga acgctttggc gattatagct tagtagagtt gcaactggag
    12541 acagggcgca ctcatcaaat ccgtgtccac atggcttata tcggccatcc agtcgctggt
    12601 gatgaggtct atggtcctcg aaagactttg aaaggacatg gacaatttct tcatgccaag
    12661 actttaggtt ttactcatcc gagaacaggt aagaccttgg aatttaaagc agatatccca
    12721 gagattttta aggaaacctt ggagagattg agaaagtaag aatgaaaaag aaattaacta
    12781 gtttagcact tgtaggcgct tttttaggtt tgtcatggta tgggaatgtt caggctcaag
    12841 aaagttcagg aaataaaatc cactttatca atgttcaaga aggtggcagt gatgcgatta
    12901 ttcttgaaag caatggacat tttgccatgg tggatacagg agaagattat gatttcccag
    12961 atggaagtga ttctcgctat ccatggagag aaggaattga aacgtcttat aagcatgttc
    13021 tgacagaccg tgtctttcgt catttgaagg aattgggtgt ccaaaaactt gattttattt
    13081 tggtgaccca tacccacagt gatcatattg gaaatgttga tgaattactg tctacctatc
    13141 cagttgaccg agtctatctt aagaaatata gtgatagtcg tattactaat tctgaacgtc
    13201 tatgggataa tctgtatggc tatgataagg ttttacagac tgctgcagaa aaaggtgttt
    13261 cagttattca aaatatcaca caaggggatg ctcattttca gtttggggat atggatattg
    13321 agctctataa ttatgaaaat gaaactgatt catcgggtga attaaagaaa atttgggatg
    13381 acaattccaa ttccttgatt agcgtggtga aagtcaatgg caagaaaatt taccttgggg
    13441 gcgatttaga taatgttcat ggagcagaag acaagtatgg tcctctcatt ggaaaagttg
    13501 atttgatgaa gtttaatcat caccatgata ccaataaatc aaataccaag gatttcatta
    13561 aaaatttgag tccgagtttg attgttcaaa cttcggatag tctaccttgg aaaaatggtg
    13621 ttgatagtga gtatgttaat tggctcaaag aacgaggaat tgagagaatc aacgcagcca
    13681 gcaaagacta tgatgcgaca gtttttgata ttcgaaaaga cggttttgtc aatatttcaa
    13741 catcctacaa gcctattcca agttttcaag ctggttggca taagagttca tatggaaact
    13801 ggtggtatca agcgcctgat tctacaggag aatatgctgt cggttggaat gaaattaagg
    13861 gtgaatggta ttactttaac caaacgggta tcttattaca gaatcaatgg aaaaaatgga
    13921 acaatcattg gttctatttg acagactctg gtgttgctgc taaaaattgg aagaaaatcg
    13981 ctggaatctg gtattatttt aacaaagaaa accagatgga aattggttgg attcaagata
    14041 aagagcagtg gtattatttg gatgttgatg gctctatgaa gacaggttgg cttcaatata
    14101 aggggcaatg gtattacttt gctccatcag gggaaatgaa aacgggctgg gtaaaagata
    14161 aagaagcctg gtactatatg gattctactg gtatcatgaa gacaggtgag atagaagttg
    14221 ctggacatca ttactatcta gaagaatcag gagctatgaa gcaaggctgg cttaaaaagg
    14281 caaatgattg gtatttctac aagacagatg gttcacgagc tataggttgg attaaagaga
    14341 aggataaatg gtacttcttg aaagaaaatg gtcaattact tgtgaatggt aagacaccag
    14401 aaggctatac tgtggattca agtggtgcct ggttagtgga tgttccgatc gagaaatctg
    14461 ctacaattaa aactacaagt cattcagaaa taaaagaatc caaagaagta gtgaaaaagg
    14521 atcttgaaaa taaagaaacg agtcaacatg aaagtgttac aaattcttca actagtcaag
    14581 atttgacatc ctcaacttca caaagctctg aaacgagtgt aaacaaatcg gaatcagaac
    14641 agtagtagaa aagaaggttt tagggccttc tttttcctat caactctttt ctatttcctg
    14701 ttattcatgt tataatggat aaatatgaat aatcggagtg agactatgaa atacaaacgg
    14761 attgtcttta aggtgggtac ttcttctctg acaaatgagg atggaagttt atcacgtagt
    14821 aaggtaaagg atattaccca gcagttggct atgctgcacg aggctggtca tgagttgatt
    14881 ttggtgtctt caggtgccat tgcggctggt tttggagcct taggatttaa aaagcgtccg
    14941 actaaaattg ctgataaaca ggcttcagca gcggtagggc agggactttt gttggaagaa
    15001 tatacgacca atcttctctt gcgtcaaatc gtttctgcac aaatcttgct gacccaagat
    15061 gactttgtgg ataagcgtcg ttataaaaat gcccatcagg ctttgtcggt tttgctcaac
    15121 cgtggggcaa ttcctatcat caatgagaat gatagtgtcg ttattgatga gctcaaggtt
    15181 ggggacaatg acactctaag tgctcaagta gcggcgatgg tccaagcaga ccttttagtt
    15241 ttcttgacag atgtggacgg tctctatact ggaaatccta attcagatcc aagagccaaa
    15301 cgcttggaga gaatcgagac catcaatcgt gagattattg atatggctgg tggagcaggt
    15361 tcgtcaaacg gaactggggg tatgttaacc aaaatcaagg ctgcaactat cgcgacggaa
    15421 tcaggagttc ctgtttatat ctgctcatcc ttgaaatcag attccatgat tgaggcggca
    15481 gaggagaccg aggatggttc ttactttgtt gctcaagaga aggggcttcg tacccagaaa
    15541 caatggcttg ccttctatgc tcagagtcaa ggttctattt gggttgataa aggggctgcg
    15601 gaagctctct ctcaacatgg aaagagtctt ctcttatctg gtatcgttga agcagaagga
    15661 gccttttctt acggtgatat cgtgacagta tttgacaagg aaagtggaaa atcacttgga
    15721 aaaggacgcg tgcaatttgg agcatctgct ttggaggata tgttgcgttc tcaaaaagcc
    15781 aagggtgtct tgatttaccg tgacgactgg atttccatta ctcctgaaat ccaactactt
    15841 tttacagaat tttagaggta aactatggtg agtagacaag aacaatttga acaggtacag
    15901 gctgttaaaa aatcgattaa cacagctagt gaagaagtga aaaaccaagc cttgctagcc
    15961 atggctgatc acttagtggc tgctactgag gaaattttag cggctaatgc cctcgatatg
    16021 gcagcggcta aggggaaaat ctcagatgtg atgttggatc gtctttattt ggatgcagat
    16081 cgtatagaag cgatggcaag aggaattcgt gaagtggttg ccttaccaga tccaatcggt
    16141 gaagttttag aaacaagtca gcttgaaaat ggtttggtta tcacaaaaaa acgtgtagct
    16201 atgggtgtca tcggtattat ctatgaaagc cgtccaaatg tgacgtctga tgcggctgct
    16261 ttgactctta agagtggaaa tgcggttgtt cttcgtagtg gtaaggatgc ctatcaaaca
    16321 acccatgcca ttgtcacagc cttgaagaag ggcttggaga cgactactat tcatccaaat
    16381 gtgattcaac tggtggagga tactagccgt gaaagtagtt atgctatgat gaaggccaag
    16441 ggctatctag accttctcat tcctcgtgga ggagctggct tgatcaatgc agtggttgag
    16501 aatgcgattg tacctgttat cgagacaggg actgggattg tccatgtcta tgtggataag
    16561 gatgcagacg aagacaaggc gctgtctatc atcaacaatg ctaaaaccag tcgtccttct
    16621 gtttgtaatg ccatggagat tctgctggtt catgaaaaca aggcagcaag catccttcct
    16681 cgcttggatc aaatgctggt tgcagagcgt aaggaagctg gactggaacc aattcaattc
    16741 cgcttggata gcaaagcaag ccagtttgtt tcaggtcaag cagctgagac ccaagacttt
    16801 gacaccgagt ttttagacta tgtccttgct gttaaggttg tgagcagttt agaagaagcg
    16861 gttgcgcaca ttgaatccca cagcacccat cattcggatg ctattgtgac ggaaaatgct
    16921 gaagctgcag catactttac agatcaagtg gactctgcag cggtgtatgt taatgcctca
    16981 actcgtttca cagatggagg acaatttggt cttggttgtg aaatggggat ttctactcag
    17041 aaattgcacg cgcgtggtcc aatgggcttg aaagagttga ccagctacaa gtatgtggtt
    17101 gctggtgatg ggcagataag ggagtaagag atgaagattg gatttatcgg tttggggaat
    17161 atgggtgcta gcttggcaaa atctgtcttg cagactagga cgtcagatga gattctcctt
    17221 gccaatcgta gtcaagctaa ggtagatgct ttcattgcag actttggtgg tcaggcttcc
    17281 agcaatgaag aaatgtttgc agaagcagat gtgatttttc taggagttaa gcctgctcag
    17341 ttttctgaac tgctttctca ataccagacc atccttgaaa aaagagaaag tcttcttttg
    17401 atttcgatgg cagctggatt gaccttagaa aaactagcaa gtcttatccc aagtcaacac
    17461 cgaattattc gtatgatgcc taatacccct gcttctatcg ggcaaggagt gattagttat
    17521 gccttgtctc ctaattgcag ggctgaggac agtgagctct tttgtcagct tttatccaag
    17581 gctggtctct tggttgaatt aggagaaagc ttaatcaatg cagcgacagg tcttgcaggc
    17641 tgtggaccag cctttgtcta tctctttatt gaagccttgg cagatgcagg tgttcagacg
    17701 ggattatcac gagaaacagc cttgaaaatg gcagcccaaa ctgtggtagg agctgggcaa
    17761 ttggtcctag aaagccagca acatcctgga gttttgaaag atcaagtttg tagtccaggc
    17821 ggttcgacta ttgctggcgt agcaagccta gaagcgcatg cttttcgagg cacagtcatg
    17881 gaggcagttc atcaagccta taaacgaaca caagaactag gtaaataaga ggtagtttta
    17941 tctgcctctt ttatggtggt tgatactctt cgaaaatcaa attcaaactg cgtcagcttc
    18001 accttgccgt actcaagtac agcctgcggc tagcttccta gtttgctctt tgattttcat
    18061 tgagtatgaa atgagaagac aaaaagattg tcacaaaccc ctattttttt gatagaatag
    18121 aagtagtaaa aaagaaatga gttagacatg tcaaaaggat ttttagtctc tcttgaggga
    18181 ccagagggag caggcaagac cagtgtttta gaggctctgc taccaatttt agaggaaaaa
    18241 ggagtagagg tgctgacgac ccgtgaacct ggcggagtct tgattgggga gaagattcgg
    18301 gaagtgattt tggatccaag tcatactcag atggatgcta aaacagagct acttctctat
    18361 attgccagtc gcagacagca tttggtggaa aaagttcttc cagcccttga agctggcaag
    18421 ttggtcatca tggatcgttt tatcgatagt tctgttgcct atcagggatt tggtcgtggc
    18481 ttagatattg aagccattga ctggctcaat cagtttgcga cagatggcct caaacccgat
    18541 ttgacactct attttgacat cgaggtggaa gaaggactgg ctcgtattgc tgctaatagt
    18601 gaccgcgagg ttaatcgttt ggatttggaa gggttggact tgcataaaaa agttcgtcaa
    18661 ggctaccttt ctcttctgga taaagaggga aatcgcattg tcaagattga tgctagtctc
    18721 cctttggagc aagttgtgga aactaccaag gctgtcttgt ttgacggaat gggcttggcc
    18781 aaatgaaaca agatcaacta aaggcttggc aaccagctca gtttgaccgt tttgtccgta
    18841 tcttagaaca agaccagctc aatcacgcct atctcttttc aggtttcttt ggaagcttgg
    18901 aaatagcgca atttttagct aagagcctct tttgtacgga taaagttggc gtcttaccat
    18961 gtgagaaatg ccgaagttgc aagctgattg aacaggaaga gtttccagat gtcaccttga
    19021 ttaagccagt caatcaggtc atcaagacag aacgcattcg ggaattggtg ggacagtttt
    19081 ctcaagcagg gattgaaagc cagcaacagg tctttatcat cgagcaagcg gataaaatgc
    19141 atcccaacgc agccaattct ctgctcaagg tcatcgaaga accccagagt gaagtttata
    19201 ttttcttctt gactagcgat gaggaaaaga tgttaccgac aatccgaagt cggactcaga
    19261 tcttccactt taaaaagcaa gaagaaaaac ttatcttact cttagaacaa atgggacttg
    19321 ttaagaaaaa agcgactctt ttagctaagt ttagtcaatc gcgagctgaa gcagaaaagt
    19381 tggctaatca ggcaagtttt tggaccttgg tcgatgaaag tgaacgcctg ctgacttggt
    19441 tagtagctaa gaaaaaagaa agttatctac aggttgccaa attagccaac ttggcagatg
    19501 ataaggaaaa acaggatcag gttttacgga ttcttgaagt tctctgtggg caggacctct
    19561 tgcaggtaag agtaagagtg attctacaag atttactaga agctagaaaa atgtggcaag
    19621 ctaatgtcag ctttcaaaat gccatggaat atctggtctt gaaagaaata taaactcaaa
    19681 aatgaatgat aaagaaagga aagggctgtt ttatggacaa aaaagaatta tttgacgcgc
    19741 tggatgattt ttcccaacag ttattggtaa ccttggccga tgtggaagcc atcaagaaaa
    19801 atctcaagag cctggtagag gaaaatacag ctcttcgttt ggaaaattct aagttgcgag
    19861 aacgcttggg tgaggtggaa gcagatgctc ctgtcaaggc caagcatgtt cgtgaaagtg
    19921 tccgtcgcat ttaccgtgat ggatttcacg tatgtaatga tttttatgga caacgtcgag
    19981 agcaggacga agaatgtatg ttctgtgatg agttgttata cagggagtag gcatgcaaat
    20041 tcaaaaaagt tttaaggggc agtctcccta tggcaagctg tatctagtgg caacgccgat
    20101 tggcaatcta gatgatatga cttttcgtgc tatccagacc ttgaaagaag tggactggat
    20161 tgctgctgag gatacgcgca atacaggtct tttgctcaag cattttgaca tttccaccaa
    20221 gcagatcagt tttcatgagc acaatgccaa ggaaaaaatt cctgatttga ttggtttctt
    20281 gaaagcaggg caaagtattg ctcaggtctc tgatgccggt ttgcctagca tttcagaccc
    20341 tggtcatgat ttggttaagg cagctattga ggaagaaatt gcagttgtta cagttccagg
    20401 tgcctctgca ggaatttccg ccttgattgc cagtggttta gcgccgcagc cacatatctt
    20461 ttacggcttt ttaccgagaa aatcaggcca gcaaaagcaa tttttcgact cgaaaaaaga
    20521 ctatcctgaa actcagattt tttatgaatc gccccatcgt gtggcagata cattggaaaa
    20581 tatgctagaa gtctacggtg accgctccgt tgtcttggtc agggaattga ccaaaatcta
    20641 tgaagaatac caaagaggta caatttctga attgctggaa agcattgctg aaacgtctct
    20701 caagggtgaa tgtcttctga ttgttgaagg tgccagtcag gatgtggaag aaaaagacga
    20761 ggaagacttg ttcttagaaa tccaagctcg tatccagcaa ggtatgaaga aaaatcaagc
    20821 tattaaggaa gtagctaaga tttaccagtg gaataagagt caactctacg ctgcctacca
    20881 cgactgggaa gaaaaacaat aaagggagac aggatgtaat aattctgtct gtttctgttt
    20941 aacttaatta gtgatgataa tataaagatg tatcacttgg tatagaagct ttggtattaa
    21001 gttttttatt aagcccatac ggaataccga tggttggagc agcagttata gcgttcttag
    21061 aaggtataaa tagaaaaata aggtcatttt aaatcaaagg attgataaat cagaaagaag
    21121 gtgatttttt gcgaacatac gaaaataaag aagaactaaa agctgagata gagaaaacat
    21181 ttgagaaata tattttagaa tttgataata ttccagaaaa tttaaaagat aagagagctg
    21241 atgaagttga cagaactcca gcagaaaacc ttgcttatca ggttggttgg accaacttgg
    21301 ttcttaaatg ggaagaagat gaaagaaagg ggcttcaagt aaaaacacca tcggataaat
    21361 ttaaatggaa tcaacttggt gaattatatc agtggttcac agatacctac gctcatttat
    21421 ctctgcaaga gttgaaagca aaattaaatg aaaatattca ttctatctct gcaatgattg
    21481 attcgttgag tgaggaagaa ttatttgaac cgcatatgag aaagtgggct gatgaagcga
    21541 ctaaaacagc gacttgggaa gtgtataagt ttattcatgt aaatacggtt gcaccttttg
    21601 gaactttcag aactaaaatc agaaaatgga agaagatagt attataaatt atatttttaa
    21661 ctttaaaaaa tttcataaaa atggttacca aaggcgatag aagaaaaact atcgtctttt
    21721 tctttgcaaa tttttaagaa gggaggtgat cttgcatgga ctttgaatat ttttataaca
    21781 gagaagcgga aagatttaac ttcttaaaag taccggagat attagttgat agagaagaat
    21841 ttcggggctt atcagcagaa gcaattatcc tttattccat acttcttaaa cagacaggaa
    21901 tgtcatttaa gaataactgg atagacaagg aaggcagagt atttatctat tttactgtcg
    21961 aagaaattat gaaaagaaga aatatctcaa agccaactgc cataaaaaca ttagatgagc
    22021 ttgatgtaaa aaaaggaata ggactgatcg aaagagtaag gcttggactt ggtaagccga
    22081 acatcattta tgttaaagac tttatgagta tatttcaggt aaaagaaaat gacttacaga
    22141 agtcaaaaaa cttaacttca gaagtaaaag attttaacct cagaagtaaa gaaaatgaac
    22201 ttcaagaggt taagaacctt gactctaact atatagagaa taataagagt aagtatagta
    22261 agagagaata tagttttggt gaaaacggac ttggaacatt tcaaaatgtg tttttagctg
    22321 ctgaagatat atcggattta caaatcataa tgaactcaca gcttgagaat tacattagac
    22381 ttcctgcaaa actagaatcc tagttcatga ttgataatac cagcaatcaa attcattcgt
    22441 aatccgaagc gtttacgatg atttcgatag gttgttgaaa acattttaaa cgtttttact
    22501 ttggtaaaga tgttctcaac cttgcttctc tccttagata gcgcatggtt acaggcttta
    22561 tcttcagctg ttagcggctt gagtttgctg gatttacgtg gagtttgtgc ttgaggatat
    22621 atcttcatga gcccttgata accactgtcg gccaagattt taccagcttg tccgatattt
    22681 ctgcaactca ttttgaacaa cttcatatca tgactatagt tcacagtgat atccaaagaa
    22741 acaattctcc cttgacttgt gacaatcgct tgagccttca tagcgtgaaa tttcttttta
    22801 ccagaatgat tcgctaattg tttttttagg gcgattgatt tgtacttccg tcgcatcaat
    22861 cattaccgtg tcctcagaac tgagaggagt tcttgaaatc gtaacaccac tttgaacaag
    22921 agttacttca acccattggc tccgacggat taagttgctt tcgtgaatac caaaatcagc
    22981 cgcaatttct tcataagttc gatattctcg cacatataga agagtggcca taagaaggtc
    23041 ttctaggctt aatttaggtt ttcgtccacc ttttgcgtgt ttaagttgat aagctgtttt
    23101 aatacagcta atatctcttc aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt
    23161 gcatcagtta gttgtttact tgcttcatca ttcatagaac tactatacca tattttgttt
    23221 cgcaggaagt ctattggaaa gtaagaaata ttgaagctga ggctattaga agaaattgtg
    23281 agcgtggtgc tattttttca ggtaaaataa aatatcacga agattcacag tttaaaggag
    23341 atcactatgt tgaatgttat gctgttttag ataatacggt tatagcaaga gatagaataa
    23401 cagtccctat cgatccgtta tgtggaaaag attttataga gtagcatata attgattctt
    23461 aactggaata ctcactatct ctttacatca agaaaatgac taaacaggga agtttgcctt
    23521 cttccctttt tttgttatac tagtagaaga aaaaatagaa agatttgtgg gagtgaaaaa
    23581 gtcctgtgga ctttttcagc ctgagccaag aaactcgaaa tctcgtaagt ctgattggct
    23641 ttttcaatgt gaatcttaac ttcacactcc caaagaggta ttagtgtcgt gtctcaatct
    23701 tatatcaatg ttatcggtgc tggtttggca ggttctgaag cagcttacca aatcgcagag
    23761 cgtggtattc cagttaaact ttatgaaatg cgtggtgtca agtcgactcc tcagcacaaa
    23821 acagacaatt ttgctgagtt ggtttgttcc aattctttgc gtggggatgc tttgacaaat
    23881 gcagttggtc ttctcaagga agaaatgcgt cgcttgggtt ctgttatctt ggaatctgct
    23941 gaggctacac gtgttcctgc cggtggagcc cttgcggtgg atcgtgatgg tttctctcaa
    24001 atggtgaccg aaaaagtggt caaccacccc ttgattgaag tggtgcgtga tgaaattaca
    24061 gaattgccaa cagatgttat tacagttgtg gcgactggtc ccttgactag cgatgccctg
    24121 gctgaaaaga ttcatgccct taataatggc gatggcttct atttctacga tgcagcagcg
    24181 cctattatcg atgtcaacac tatcgatatg agtaaggtct atctcaaatc tcgttatgat
    24241 aagggagaag cagcctatct caatgctcca atgaccaagc aagagtttat ggatttccat
    24301 gaagccttgg tcaatgcgga agaagcaccg ctcaattctt ttgaaaaaga aaagtacttt
    24361 gaaggatgta tgccaatcga agttatggcc aaacgtggca ttaaaactat gctttatggc
    24421 cctatgaagc cagtcggtct tgagtatccg gacgactaca caggacctcg tgatggagaa
    24481 tttaaaacac cttatgcggt tgtgcaactt cgtcaggata atgcagctgg tagcctctac
    24541 aatattgttg gtttccagac ccacctcaaa tggggagaac aaaagcgtgt cttccaaatg
    24601 attccgggtc ttgaaaatgc ggagtttgtc cgttatggtg tcatgcatcg caattcttac
    24661 atggattcac caaatcttct tgagcagact taccgttcta agaaacaacc aaatctcttc
    24721 tttgctggtc agatgacggg tgtggaaggc tatgttgagt cggcggcttc aggcttagtt
    24781 gcgggaatta acgcagctcg tctcttcaag gaagaaagcg aggctatttt ccccgagacg
    24841 acagcgattg gaagcttagc tcattacatt acccatgccg acagcaaaca tttccaacca
    24901 atgaatgtca attttgggat catcaaggag ttggaaggcg agcgtatccg tgataagaag
    24961 gctcgttatg aaaaaattgc agagcgtgcc cttgccgact tagaggaatt tttgactgtc
    25021 taattttttt gaaagaattg ctcatgatac tataaaaatc ttagaaattg tgataaaata
    25081 ggtaggatga aagaaggaga gtgaaaatgg cgaatcccaa gtataaacgt attttaatca
    25141 agttatcagg tgaagccctt gccggtgaac gtggcgtagg gattgatatc caaacagttc
    25201 aaacaatcgc aaaagagatt caagaagttc atagcttagg tatcgaaatt gcccttgtta
    25261 tcggtggagg aaatctctgg cgtggagaac ctgcagcaga agcaggtatg gaccgtgttc
    25321 aggcagatta cactggaatg cttgggactg ttatgaatgc tcttgtgatg gcagattcat
    25381 tgcaacaagt tggggttgat acacgtgttc aaacagctat tgccatgcaa caagtggcag
    25441 agccttatgt acgtggacgt gctcttcgcc accttgaaaa aggccgtatc gttatctttg
    25501 gtgctggaat tggttcacct tacttctcaa ccgatacaac agcggctctt cgttcagctg
    25561 aaatcgaagc ggatgccatt cttatggcta aaaatggtgt cgatggtgtg tacaatgccg
    25621 atcctaagaa agataagaca gctgttaagt ttgaagaatt gacccaccgt gacgttatca
    25681 ataaaggtct tcgtatcatg gactcaacag cttcaaccct ctcaatggac aacgacattg
    25741 acttggttgt cttcaacatg aaccaatcag gcaacatcaa acgtgtcgta tttggtgaaa
    25801 atatcggaac aacagtttca aataatatcg aagaaaagga ataagaaaga atatggctaa
    25861 cgcaattatt gaaaaagcta aagagagaat gacccagtct caccaatcac ttgctcgtga
    25921 atttggtggt atccgtgctg gccgtgccaa tgcaagcttg cttgaccgtg tacatgtaga
    25981 atactatgga gtcgaaactc ctcttaatca aatcgcttca attacgattc cagaagcgcg
    26041 tgttttgttg gtaacaccat ttgacaagtc ttcattgaaa gacatcgaac gtgccttgaa
    26101 cgcttctgat cttggtatca caccggctaa tgacggttct gtgattcgct tggttatccc
    26161 agctcttaca gaagaaactc gtcgtgacct tgctaaagaa gtgaagaagg tcggcgaaaa
    26221 tgctaaagtg gctgtccgca atatccgtcg cgatgctatg gacgaagcta agaaacaaga
    26281 aaaagcaaaa gaaatcactg aagacgaatt gaagactctt gaaaaagaca ttcaaaaagt
    26341 aacagacgat gctgttaaac acatcgacga tatgactgcc aacaaagaga aagaactttt
    26401 ggaagtctaa aaataaacag aaaaactcag ttggcattgc tggctgagtt ttattcgaaa
    26461 gaaggaaata tgaatacaaa tcttgcaagt tttatcgttg gactgatcat cgatgaaaat
    26521 gaccgttttt actttgtgca aaaggatggt caaacctatg ctcttgctaa ggaagaaggt
    26581 caacatacag taggggatac ggtcaaaggt tttgcataca cggatatgaa gcaaaaactc
    26641 cgcctgacaa ccttagaagt gactgccact caggaccaat ttggttgggg atgtgtcaca
    26701 gaggttcgta aggacttggg tgtctttgtg gatacaggcc ttcctgacaa ggaaatcgtt
    26761 gtgtcactcg atattctccc tgagttcaag gaactctggc ctaagaaggg cgaccaactc
    26821 tacatccgtc ttgaagtgga taagaaagac cgtatctggg gcctcttggc ttatcaagaa
    26881 gacttccaac gtctcgctcg tcctgcctac aacaacatgc agaaccaaaa ctggccagcc
    26941 attgtttacc gtctcaagct gtcaggaact tttgtttacc taccagaaaa taatatgctt
    27001 ggttttattc atcctagcga gcgttacgca gagccacgtt tggggcaagt attagatgcg
    27061 cgcgttattg gtttccgtga agtggaccgc actttgaacc tctccctcaa accacgctcc
    27121 tttgaaatgt tggaaaacga tgctcagatg attttgactt atttggaaag caatggcggt
    27181 ttcatgacct taaatgacaa gtcatctcca gacgacatca aggcaacctt tggcatttct
    27241 aaaggtcagt tcaagaaagc tttaggtggt cttatgaagg ctggtaaaat caagcaggac
    27301 cagtttggga cagagttgat ttagggaggt ttatgagaaa atcattttac acttggctca
    27361 tgaccgagcg caatcctaaa agtaacagtc ccaaagcaat tttggcagac ctcgcttttg
    27421 aagaggcagc ttttccaaaa catacagatg attttgatga ggtcagtcgc tttttggagg
    27481 agcatgccag tttctctttt aacctaggag attttgacag catttggcag gaatatctag
    27541 aacactagca tttattcatt gggtttgggc tagtaatttc tccatccctc tgctataata
    27601 aaaagaaata aaaggattag agaggttctt tatttgaagg aacattcaat agacattcaa
    27661 ctgagtcatc cagatgacct gtttcatctt tttggttcca atgagcgcca tcttcgtttg
    27721 atggaagaag agctggatgt ggtgattcat gctcgtacgg agattgtcca ggttttggga
    27781 gaagagtctg cttgtgagga agcccgtcag gttattcaag ctctcatggt cttggtgaac
    27841 cgtgggatga ccgttggtac gccagatgta gtgacggcta ttagtatggt caaaaacgat
    27901 gaaattgata agtttgtcgc cctttacgaa gaagaaatta tcaaggataa tactgggaaa
    27961 ccgatccgcg tcaaaacctt aggtcaaaaa ctttatgtgg acagtgtcaa acagcatgat
    28021 gtgacctttg gaattgggcc tgcagggacg gggaagacct ttcttgcagt tactttggca
    28081 gtgactgccc ttaaacgtgg gcaagtcaag cggattatct tgacacgtcc agcggtggaa
    28141 gcaggagaga gtctaggttt tcttccgggt gatcttaagg agaaggtaga tccttacctt
    28201 cgtcctgttt acgatgcctt gtatcagatt ctggggaaag accaaacgac tcgtctcatg
    28261 gagcgtgaaa ttatcgaaat tgcgcccctt gcctatatgc gtggccggac cttggatgat
    28321 gcctttgtca ttctcgatga ggcgcaaaac acgaccatca tgcagatgaa gatgttcttg
    28381 acgcgtttag gctttcattc taagatgatt gtcaatggag atatcagtca gattgacctg
    28441 ccacgtaatg tcaagtccgg tttgattgat gctcaagaga aactcaagaa catccatcag
    28501 attgactttg ttcatttttc agccaaggat gtggttcgcc atccagttgt cgctcagatt
    28561 atccgagcct atgaatattc tactgaagtt gcacacgact gattttgagg aagttcgcct
    28621 gcaaaagaat atacttttga gagaggaaaa tccagttgta taggctaaag gttttatcca
    28681 aaggtctgag acaacgatta ggcacgatgg aaagaacttt tatgtggctg atgacgatca
    28741 gtgcatcttc ctgtgtcata atcacagggc acaagaaagt aggaatttga aaagatgatt
    28801 gaccaactat ctaagtatta cagttgtagg atactaactg aaaaggatat tccaagtatt
    28861 ttatctttat atgaaagtaa tcctctgtat tttcagcatt gtccaccaga gccaaatttt
    28921 gcaactgtaa aagaggacat gctttgtcta cctgaaggta aagctaaggc tgataagttt
    28981 tttgttggat tttggaatgg atctgacctt gtggctgtta tggattttgt ctatgcatat
    29041 cctgatgagg agactgtttt tattggtttg tttatggttg atcaagccta tcagagaaaa
    29101 gggattggta gtcatattgt gacagaagca ctagcttatt ttgctaagaa ctttcgaaag
    29161 gcacgtttgg cttatgttaa gggaaatccg caatctcagc atttttggga aaagcagggc
    29221 tttaaatcaa ttggatgcga ggttaagcaa gaactctata cggttgttat cgctgaacag
    29281 agcctagaag attagaaatg gcatcaagta agaactattt ggaatttgtt ttggaacaat
    29341 tatcaggatt agatgatgtg acttaccgtt ccatgatggg ggagtatatt ctttacttcc
    29401 gcggcaagat tattggcggc atttatgacg atcgcttttt agttaaaccc gtgcaagcag
    29461 tcttagataa gattgaccaa tcttcttttg agtttccata caaaggtgcc aaagaaatga
    29521 tttgagtgga agaacttgat aataagatgt ttctataaga cctgatttta gctatgtata
    29581 accaactgcc aacgcccaaa cctaaaaaga aaaagcaagg gtgaacgaag taaaaaagaa
    29641 gtctgctaag gccctgtctt tgcacgggta aaattttata tataaaaaga agctgggact
    29701 aaagagctca gcttcctttg gtttatataa ttgtcattac aagacgaagt ggttgggcga
    29761 aactctgttg actttattca atttagagtt tcttatgcac aattgagtct ggaacgaaag
    29821 tctccagttg caaagtatac agtacaataa accaacgatg taatagctga tgacacaaag
    29881 cacagtgggt aggacttgcg aagtcaccct tttcttttca aaatttatac taaatcattg
    29941 atatcagtgt agtcacgatt aagtccttga gcaactggta ggttagtcaa gtaaccttga
    30001 taagtagtca caccttgacg caagccttca tcttcagaga ttgcttgtgc gaatcctttg
    30061 ccagccaaag cttcgatata aggaagagtg acattggtta gggcgatggt tgaagtgcga
    30121 gcaaccgcac cagggatatt ggcaacggca tagtggagaa caccgtgttt ttcatagacg
    30181 ggttcatcgt gcgttgtcac acggtcagct gtttcgataa cgccaccttg gtcaacagca
    30241 acgtcaacga tacagagcct ggacgcattt gtttgaccat ctcatctgtc accaattccg
    30301 gtgcttttgc accagggatg agaatggctc caatcaccac atcagcatct ctcacacttg
    30361 cttcaatgtt gaatgaatta gacataagag tttgaatttg acttccaaag acttcttcta
    30421 gaactgagag acgcttggca ctaatatcta aaatagtcac ttgagcacca agaccaaggg
    30481 cgatgcgggc agcatgtgta ccgacgacac catcaccgat gatagttact tttccttttg
    30541 gaacacctgg tacaccacca agtagaacac cagagccacc agcttgctta gtaaggaagt
    30601 gagctccgat ttaaacagcc atacgacctg caacctcact cataggaacg aggagcggta
    30661 gttgtccttg attgtcacga acagtttcat aggcaattcc tgttgttttt gctgctaaca
    30721 tagcatctgc taattctgga gcagcggcca tgtgcaagta ggtgaagaga agaagatcgt
    30781 cgcgcaagta accgtattca gaacttaaag gttcttttac tttcacaacc aactctgctg
    30841 cccaagcttc accagcagta gcgacaatct cagctccttg cttttgatag tcagcatcag
    30901 taaagccaga accgagacca gcatttgttt cgataaggac acgatgacca cgactaacta
    30961 agctatgaac acctgcaggt gtgagggcga cacggttttc gttattttta atttcttttg
    31021 ggattccgat taacattgag ataacctacc tttcaattga cggtcttgtt ttggttgtca
    31081 cattccagtt cataaatcaa aaatgtaacg gtttcattgt atatgaaacc gcttcaaaaa
    31141 tcaagaaaaa cttgtcatcc caattttttt atgctagact agtgaaaatc aagctctaat
    31201 ggagggaaaa gtatggaatc aatttttgta aaacttgccc agtatccgtc tatagaaacg
    31261 gagcgtttat tgcttagacc tgtaactttg gatgatgcgg aagcaatgtt tgactatgcc
    31321 tcggacaagg gtaatacacg ttacactttt ccaaccaatc aaagcttgga agaaaccaag
    31381 aataacattg ctcagttcta cttggctaat cccttgggac gttggggaat agaactaaaa
    31441 agcaatggca aatttatcgg aacaattgat ttgcacaaga ttgatcctgt tcttaagaag
    31501 gtagctattg gttatattat caaccaaacg tattggaatc aaggattaac gacagaaacc
    31561 aatcgtgctg tgattgagct agcttttgag aagataggaa tgaataagtt agttgcttta
    31621 tacgataagg ctaatcccgc atcaggaaag gtcatggaga aatcaggaat gcgtttttcc
    31681 catgcagaac catatgcttg tatggaccag catgaaaaag gccgaatcgt gacaagagtt
    31741 cattatgtct tgaccaagga agactatttt gcaaataaat aagcagttga aaagaaattt
    31801 ttcgactgtt ttttcttcct cttacgaata atctaagaga ggagaaaata tggaagcaat
    31861 tatcgagaaa atcaaagagt ataaaatcat cgtcatctgt actggtctgg gcttgcttgt
    31921 aggaggattt ttcctgctaa aaccagctcc acaaacacct gtcaaagaga cgaatttgca
    31981 ggctgaagtc gcagctgttt ccaaggattt ggtatccgaa gaggaagtga acaaggaaga
    32041 aaaggaagaa ccccttgaac aagatctaat cacagtagat gtcaaaggtg ctgtcaaatc
    32101 gccagggatt tatgacttgc ctgtaggtag tcgagtcaat gatgctgttc agaaggctgg
    32161 tggcttgaca gagcaagcag acagcaagtc gctcaatcta gctcagaaag ttagtgatga
    32221 ggctctggtt tacgttccta ctaagggaga agaagcagtt agccaacaga ctggtttggg
    32281 gacagcttct tcaataagca aggaaaagaa ggtcaatctc aacaaggcca gtctggaaga
    32341 actcaagcag gtcaagggac tgggaggaaa acgagctcag gacattatcg accatcgtga
    32401 ggcaaatggc aagttcaagt cagtagacga gctcaagaag gtctctggca ttggtggcaa
    32461 aacaatagaa aagcttaaag actatgttac agtggattaa gaatttctct attcccctaa
    32521 tttacctgag ttttctatta ctttggcttt attacgctat tttctcagca tcttatcttg
    32581 ctttgttggg ctttgttttt ctgctagtct gtctctttat ccaatttccg tggaaatctg
    32641 ctggtaaagt tctaataatt tgcggaatct ttggattttg gtttgttttt caaaattggc
    32701 aacagagtca agcgagtcaa aatctggcgg attctgttga aagggtacgg attttacctg
    32761 atactattaa ggttaatggt gatagtctat cctttcgtgg caagtctaac ggtcgtgctt
    32821 tccaagtcta ttataaactc cagtccgagg aggagaaaga agcctttcaa gctttaaccg
    32881 acctgcatga gataggacta gaagggaagc tttcggagcc agaagggcag agaaattttg
    32941 gtggctttaa ttaccaagcc tatctgaaga ctcagggaat ttaccagact ctcaatatca
    33001 aaaaaatcca gtcacttcaa aagattggca gttgggatat aggagaaaac ttgtccagtt
    33061 tacgtcgaaa ggctgtggtt tggattaaga cgcactttcc agaccctatg cgcaattaca
    33121 tgacaggact cttgctggga catctggaca ccgactttga ggagatgagt gagctttatt
    33181 ccagtctagg aattatccac ctctttgccc tatctggcat gcaggtaggt tttttcatga
    33241 atggatttaa gaaacttctc ttgcgattgg gcttgaccca agaaaagttg aaatggctga
    33301 cttatccctt ttcccttatc tatgcgggac taactggatt ttcagcatcg gttattcgca
    33361 gtctcttgca aaagctactg gctcaacatg gggttaaggg cttggataat tttgccttga
    33421 cggtgcttgt cctctttatt gtcatgccaa actttttctt gacagcagga ggagtcttgt
    33481 cctgcgctta tgcttttatc ctgaccatga ccagcaaaga agggaagggg ctcaaggctg
    33541 ttgctagtga aagtctagtc atctccttgg gcatattgcc cattctatcc ttctattttg
    33601 cggaatttca accttggtct atccttttga cctttgtctt ttcctttcta tttgacttga
    33661 ccttcttacc gctcttgtct attttatttg tcctttcctt tctctatcca gtcattcagc
    33721 tgaactttat ctttgaatgg ttggagggca ttattcgctt ggtctcacag gtgacaagta
    33781 ggcctctagt ctttggacaa cccaacgcat ggcttttaat cttattgtta atttctttgg
    33841 ctttggtcta tgatttgagg aaaaacatta aaggattaac agtattgagt ttattgatta
    33901 caggtctctt tttcttgacc aagtatccac tggaaaatga aatcaccatg ctggatgtgg
    33961 ggcaaggaga aagtattttc ctacgggatg taactgggaa aaccattctc atagatgtag
    34021 gtggtaaggc agaatcttat aagaaaatcg aaaaatggca agaaaagatg acgaccagca
    34081 atgcccagcg aaccttgatt ccctatctca aaagtcgagg agtagctaag attgaccagc
    34141 taattttgac taacacggac aaggagcatg ttggagattt gtcagaggtg accaaggctt
    34201 tccatgtagg ggagattcta gtatcaaaag acagtctgaa acagaaggaa tttgtggcag
    34261 aactacaggt gactcaaaca aaggtgcgta gtatgacagt aggggagtac ttgcccattt
    34321 tcggaagtca gttagaagtc ctatctccaa gggaaattgg atatggaggt catgaagatt
    34381 ccctggttct ttatgggaaa ctcttgaata atcactttct cttcatagga aatttggagg
    34441 agaaaggaga gaaggacttg ctgaagtact atccagactt gaaagtaaat gttttgaaag
    34501 ctagccaaca tggcaataaa aaatcatcaa gtccagcctt tctagaaaaa ctcaaaccag
    34561 agcttactct tatctcagtt ggaaagagca atcgaatgaa actcccccat caggaaacat
    34621 tgacacgact ggaaggtatc aatagcaaag tttaccgaac tgaccagcaa ggagctatac
    34681 gctttaaggg gttggatagt tggaaaatcg aaagtgttcg ataggaagga taaatgttgt
    34741 agattagtga aataaactaa aaatttgttg cataataatg ataaaaatgg tataatgaaa
    34801 acgtattcaa tattgaggat ataaaatcat taaaaattag caaaaatcgt ttaattagtt
    34861 agtttatgat tattggtctt tttcagtcca gtatatctgc tgtgacagtc actaaaagtt
    34921 acaagtatga ttggaatacg gtttgggaat atagtaccaa ctatcacgac catcagtatg
    34981 cttggattcc gtcatggtct cgttatgaca gctattctga gtatccagtt ggttctggct
    35041 ggaactacgg tcgttatgag gtcataaact attacagcgg aggctattaa tccttaaaga
    35101 gtgagaaaag gagggctgga tatgttaaat cttactcatg ttaccttaaa aacgcgacaa
    35161 gtcatcttgc aagatgcgga ttttaccttt aaaaagggta ggatttatgg ccttcttgct
    35221 atcaatggct cgggaaagac gaccctgttc cgtgccatta gcaatttaat tcccataagt
    35281 agtggaaata tcgcagcccc tccttcttta ttttattatg agagtattga atggctggat
    35341 ggaaacttaa gtgggatgga ctaccttcgt cttatcaaaa acatctggaa gtcaggtctg
    35401 aacttgaggg atgaaatcgc ctattgggaa atgtctgatt atatcagcct tcccattcgc
    35461 aagtattcct taggcatgaa gcaacgcttg gtgattgcca tgtatttcct cagtcaggcc
    35521 aaatgctggc tcatggatga gattacaaat ggcttagatg agtattatcg acagaagttt
    35581 tttgataggc tagcacaaat cgatagacaa gaacagctgg ttcttttaag ttcccactat
    35641 aaggaagagt tggttgatgt ctgcgataga gtagtaacca ttcatcaggg gcagatagaa
    35701 gaggtttagt ttatgaaaga tgttagtcta tttttattga aaaaagtttt caaaagtcgt
    35761 ttaaactgga ttatcttact tttatttgca tctgtactcg gtgttacctt ttatttaaat
    35821 agtcagactg caaactcaca cagcttggag agcaggttgg aaagtcgcat tgcagccaac
    35881 gagagggcta tcaatgaaaa tgaagagaaa ctctcccaaa tgtctgatac cagctcggag
    35941 gaataccagt ttgctaaaaa taatttagac gtgcaaaaaa atcttttgac gcgaaagaca
    36001 gaaattctaa ctttactaaa agaagggcgc tggaaagaag cctactatct gcagtggcaa
    36061 gatgaagaga agaattatga atttgtatca aatgacccga ctgctatctc tggcttaaaa
    36121 atgggggttg accgcgaacg gaagatttac caagccctgt atcccttgaa cataaaagca
    36181 catactttgg agtttccgac ccacgggatt gatcagattg tctggatttt agaggttatc
    36241 atcccaagct tgtttgtggt tgcgattatt tttatgctaa cacaactatt tgcagaaaga
    36301 tatcaaaatc atctggacac agctcactta tatcctgttt caaaagtgac atttgcaata
    36361 tcctctcttg gagttggagt gggatatgta actgtgctgt ttatcggaat ctgtggcttt
    36421 tcttttctag tgggaagtct gataagtggt tttggacagt tagattatcc ctacccaatt
    36481 tatagcttag tgaatcaaga agtaactatt gggaaaatac aagatgtatt atttcctggc
    36541 ttgctcttag ctttcttagc ctttatcgtc attgtggaag ttgtgtactt gattgcttac
    36601 tttttcaagc aaaaaatgcc tgtcctcttt ctttcactca ttgggattgt tggcttattg
    36661 tttggcatcc aaacaattca gcctcttcaa aggattgcac atctgattcc ctttacttac
    36721 ttgcgttcag tggagatttt atctggaaga ttatctaagc agattgataa tgtcgatcta
    36781 aattggagca tggggatggt cttacttcct tgcctgatta tctttttgct agtggggatt
    36841 ctatttatcg aaaactgggg aagttcacgt aaaaaggaag tttttaatag gtcttagcat
    36901 tcttataagg aagttaagga aaaactaaca tagagaggga atcaacttga ttctctcttt
    36961 ttaattcgaa aaccaaaata caaacacaaa cttttcaaaa aataactttt tatcttgaca
    37021 agagctagaa aacttggtat catataaaag ttgagaaaag cagaagtgag agcttctcgc
    37081 cttgtgacat taagttgcct ggccctacgg atgaaaagtt tcgaagaaac gctatcataa
    37141 cgtgcgggct tgtatattta cgagtccgct attgtttttc tctaataaaa caaaagaggt
    37201 gaaaaccata gcaaagcaag acttattcat caatgatgag attcgtgtac gtgaagttcg
    37261 cttgattggt cttgaaggag aacagctagg catcaagcca ctcagtgaag cgcaagcttt
    37321 ggctgataac gctaatgttg acctagtatt gattcaaccc caagccaaac cgcctgttgc
    37381 aaaaattatg gactacggta agttcaaatt tgagtaccag aagaagcaaa aagaacaacg
    37441 taaaaaacaa agcgttgtta ctgtgaaaga agttcgtcta agtccaacaa ttgacaaggg
    37501 tgactttgat acaaaacttc gtaatgcacg taagttcctt gaaaaaggaa ataaagttaa
    37561 ggtatctatt cgctttaagg gtcgtatgat tacccataaa gagattggtg caaaagtttt
    37621 agccgagttt gctgaagcaa ctcaagatat tgccatcatc gaacaacgtg ctaaaatgga
    37681 tggacgtcaa atgttcatgc aattggcgcc agcgactgac aaaaaataat tgtcagaaag
    37741 ttaaataaag gagaaaaaat catgccaaaa caaaaaacac accgcgcatc agctaaacgt
    37801 ttcaaacgta caggttctgg tggacttaaa cgtttccgtg cttacacttc tcaccgtttc
    37861 cacggaaaaa ctaagaaaca acgtcgtcat cttcgtaaag catctatggt gcattcagga
    37921 gattacaaac gtatcaaagc aatgcttact cgcttgaaat aatagcttga ctgtaagtaa
    37981 acaattctag gaaatatttg gaggaaataa aacatggcac gtgttaaagg tggcgttgta
    38041 tcacgcaaac gtcgtaaacg tattcttaaa ttagcaaaag gttactatgg agctaaacac
    38101 atcttgttcc gtactgcaaa agaacaagta atgaactctt actactatgc ataccgtgac
    38161 cgtcgtcaga aaaaacgtga cttccgcaaa ttgtggatta ctcgtatcaa tgcggcagct
    38221 cgtatgaacg gactttcata ctcacaattg atgcatggtt tgaaattggc tgagatcgaa
    38281 gttaaccgta aaatgcttgc tgacttggct gttaacgatg cagtagcttt cacagctctt
    38341 gcagatgcag ctaaagcaaa acttggtaaa taacaactga tgagactgga acaggattgt
    38401 ccagtctttt taaaaataaa ggagaaagat atggcttcaa aaatgctaca cacttgctta
    38461 cgagtagaaa atcttgaaaa atcaatcgca ttttatcaag atgcttttgg ttttaaagaa
    38521 ttgcgtcgca gagattttcc agaccatgcc ttcacgattg tctatctagg tcttgagggt
    38581 gatgattatg agttggagtt gacttataac tacgatcacg gtccgtatgt ggttggtgat
    38641 gggtttgccc atatcgccct cagtacacct gatcttgagg cacttcatca agaacacagt
    38701 gcaaaaggct atgaagtgac tgagccaaat ggtctaccag gaactacacc aaactattac
    38761 tttgttaaag accctgatgg atataaggtc gaagtcattc gtgaaaaata atttcgtgca
    38821 agttaagtag aatattcgtt ttctacttga ctttttttag ctgaaagagt atactaataa
    38881 aaattcaacc tttaagggga gtccagagag actcacaagg tgtcagataa aagaatagtg
    38941 caattttcta gaggagacct tttgagtgtg ctctcttgtg ttgtacgatt ttaactgagg
    39001 ccttgcacta gcaaggtctt ttctttatct ggtcccctta aaatttaagg aggaaaagtt
    39061 atgaatctca catgtaagaa gcgtttgggt gtcattcggt tggaaaccat gaaggtggtt
    39121 gcacaagagg aaatcgcgcc agcaatcttt gaattagtcc tagaaggaga aatggttgaa
    39181 gccatgcgag caggccaatt tcttcatctg cgtgtaccag acgatgccca tctcttacgt
    39241 cgtcctattt caatttcgtc tattgacaag gcaaacaagc agtgtcacct catttatcgg
    39301 attgagggag ctgggactgc aattttttca accttaagtc agggagacac tcttgatgtg
    39361 atggggcctc agggaaatgg ttttgacttg tctgaccttg atgagcagaa tcaggttctc
    39421 cttgttggtg gtgggattgg tgttccaccc ttgcttgagg tggccaagga attgcatgaa
    39481 cgtggagtga aagtagtgac agtcctcggt tttgctaata aggatgctgt tattttgaaa
    39541 acggaattgg ctcagtatgg tcaggtcttt gtaacgacag atgatggttc ttatggcatc
    39601 aagggaaatg tttccgttgt tatcaatgat ttagatagtc agtttgatgc tgtttactcg
    39661 tgtggggctc caggaatgat gaagtatatc aatcaaacct ttgatgatca cccaagagcc
    39721 tatttatctc tggaatctcg tatggcttgt gggatgggag cttgctatgc ctgtgttcta
    39781 aaagtaccag aaagcgagac ggtcagccaa cgcgtctgtg aagatggtcc tgttttccgc
    39841 acaggaacag ttgtattata aggagaaaat tatgactaca aatcgattac aagtgtccct
    39901 acctggtttg gatttgaaaa atccgattat tccagcatca ggctgttttg gctttggaca
    39961 agagtatgcc aagtactatg atttaaacct tttaggttct attatgatca aggcgacaac
    40021 ccttgaacca cgttttggga acccaactcc aagagtagca gagacgcctg ctggtatgct
    40081 caatgcaatt ggcttgcaaa atcctggttt agaggttgtt ttggctgaaa agttaccttg
    40141 gctggaaaga gaatatccaa atcttcctat tattgccaat gtagctggtt tttcaaaaca
    40201 agagtatgca gctgtttctc atgggatttc caaggcaact aatgtaaaag ctatcgagct
    40261 caatatttct tgtcccaatg ttgaccactg taatcatgga cttttgattg gtcaagatcc
    40321 agatttggct tatgatgtgg tgaaagcagc tgtggaagcc tcagaagtgc cagtttatgt
    40381 caaattaacc ccgagtgtga ccgatatcgt tactgtcgca aaagctgcag aagatgcggg
    40441 agcaagtggc ttgaccatga tcaatactct ggttggaatg cgctttgacc tcaaaaccag
    40501 aaaaccaatc ttggccaatg gaacaggtgg aatgtcaggt ccagcagtct ttccagtagc
    40561 cctcaaactc atccgccaag tagcccaaac aacagacctg cctatcattg gaatgggggg
    40621 agtggattcg gctgaagctg ccctagaaat gtatctggct ggggcatctg ctatcggagt
    40681 tggaacagct aactttacca atccttatgc ctgccctgac atcatcgaaa atttaccaaa
    40741 agtcatggat aaatacggta ttagcagtct ggaagaactc cgtcaggaag taaaagagtc
    40801 tctgaggtaa actacaatca atctgttctt gattttttat tagtttgtaa tatgaattta
    40861 ggagaatttt ggtacaataa aataaataag aacagaggaa gaaggttaat gaagaaagta
    40921 agatttattt ttttagctct gctatttttc ttagctagtc cagagggtgc aatggctagt
    40981 gatggtactt ggcaaggaaa acagtatctg aaagaagatg gcagtcaagc agcgaatgag
    41041 tgggtttttg atactcatta tcaatcttgg ttctatataa aagcagatgc taactatgct
    41101 gaaaatgaat ggctaaagca aggtgacgac tattttcacc tcaaatctgg tggctatatg
    41161 gccaaatcag aatgggtaga agacaaggga gccttttatt atcttgacca agatggaaag
    41221 atgaaaagaa atgcttgggt aggaacttcc tatgttggtg caacaggtgc caaagtaata
    41281 gaagactggg tctatgattc tcaatacgat gcttggtttt atatcaaagc agatggacag
    41341 cacgcagaga aagaatggct ccaaattaaa gggaaggact attatttcaa atccggtggt
    41401 tatctactga caagtcagtg gattaatcaa gcttatgtga atgctagtgg tgccaaagta
    41461 cagcaaggtt ggctttttga caaacaatac caatcttggt tttacatcaa agaaaatgga
    41521 aactatgctg ataaagaatg gattttcgag aatggtcact attattatct aaaatccggt
    41581 ggctacatgg cagccaatga atggatttgg gataaggaat cttggtttta tctcaaattt
    41641 gatgggaaaa tagctgaaaa agaatgggtc tacgattctc atagtcaagc ttggtactac
    41701 ttcaaatccg gtggctacat ggcagccaat gaatggattt gggataagga atcttggttt
    41761 tacctcaagt ttgatggcaa aatggctgaa aaagaatggg tctacgattc tcatagtcaa
    41821 gcctggtact acttcaaatc cggtggttac atgacagcca atgaatggat ttgggataag
    41881 gaatcttggt tttatctcaa atctgatggg aaaatagctg aaaaagaatg ggtctacgat
    41941 tctcatagtc aagcttggta ctacttcaaa tccggtggtt acatgacagc caatgaatgg
    42001 atttgggata aggaatcttg gttttacctc aagtctgatg gcaaaatggc tgaaaaagaa
    42061 tgggtctacg attctcatag tcaagcctgg tactacttca aatctggtgg ctacatggcg
    42121 aaaaatgaga cagtagatgg ttatcagctt ggaagcgatg gtaaatggct tggaggaaaa
    42181 gctacaaatg aaaatgctgc ttactatcaa gtagtgcctg ttacagccaa tgtttatgat
    42241 tcagatggtg aaaagctttc ctatatatcg caaggtagtg tcgtatggct agataaggat
    42301 agaaaaagtg atgacaagcg cttggctatt actatttctg gtttgtcagg ctatatgaaa
    42361 acagaagatt tacaagcgct agatgctagt aaggacttta tcccttatta tgagagtgat
    42421 ggccaccgtt tttatcacta tgtggctcag aatgctagta tcccagtagc ttctcatctt
    42481 tctgatatgg aagtaggcaa gaaatattat tcggcagatg gcctgcattt tgatggtttt
    42541 aagcttgaga atcccttcct tttcaaagat ttaacagagg ctacaaacta cagtgctgaa
    42601 gaattggata aggtatttag tttgctaaac attaacaata gccttttgga gaacaagggc
    42661 gctactttta aggaagccga agaacattac catatcaatg ccctttatct ccttgcccat
    42721 agtgccctag aaagtaactg gggaagaagt aaaattgcca aagataagaa taatttcttt
    42781 ggcattacag cctatgatac gaccccttac ctttctgcca agacatttga tgatgtggat
    42841 aagggaattt taggtgcaac caagtggatt aaggaaaatt atatcgatag gggaagaact
    42901 ttccttggaa acaaggcttc tggtatgaat gtggaatatg cttcagaccc ttattggggc
    42961 gaaaaaattg ctagtgtgat gatgaaaatc aatgagaagc taggtggcaa agattagtac
    43021 tataagtgaa tatgatttga gtgaatagta agttaaaaat cctgatttca agtaaaatca
    43081 ggattttttc atggatgcaa tttttttgga gtctggtgtg acgcggaggg tcttttgtcc
    43141 tgtgtaagtg acaaagccgg gttttccacc agttggttta ttgagttttt tgacttcaat
    43201 catatctacc tgcaccagat tcgacaggcg cccttgagag aagtaggcag ctaactctgc
    43261 tgcgtctgtc ttgactgcat cagatgggtc aagatttcct gagatgacaa catggcttcc
    43321 aggaatgtcc ttagcatgga accaaagttc ctccttgcgg gccattttaa aggtcaattc
    43381 ctcattttga agattgtttc gtccgacata gatgatggtt ttgccatcgc ttgctagata
    43441 ttgttctagt tttttgcgtt tctggatttt ctcccgttgt cttctgcgga taaaacctgt
    43501 ttgaatcaat tcttcacgga tttcagcgat ttcttccagt ccagcttggt tgaggacggt
    43561 ttctacactt tccagataga gaatagtggc tttggtttct tcaatcaaat cagtcaagta
    43621 tttgacagct tctttgagtt tctgataccg tttaaaatag cgttgggcat tctggttggg
    43681 agtcagagcc ttatcaagcg caatcatgat aggttggttg gtatagtagt tgtctaggat
    43741 aacctggtct tggtcgttag gcacttggtg taggaaggtt gtcagcaatt ctcctttttg
    43801 acgaaattct tcagcgttgt ctgtcgccag taactctttt tcctgttttt tgagtttgtg
    43861 tcggtttttc tgaagttcat tttcaacacg acgaatcagt tcactggcct gctgtttgac
    43921 gcggtcgcgc tcagccttat ccttatagta ggtgtccaac aaatcagaaa gatttgcaaa
    43981 aggctctccc acctgatttg caaaaggaac tggactgaag gaagtctcag tcaagcatgg
    44041 cttggtttct tgattgaaaa aatttcggaa agcggaaagt ttttcactaa ccagtatcct
    44101 ttccaattca tttgccgtat cgcgtcccag accttgaaag aggctttgaa gattttttgc
    44161 tgttagttct tgggtttgca ggatttcaaa gagcttttca tccttgatag taaaaggatt
    44221 gagagattct gtacttggcg gagcgatata ggtcgatcct ggaagtaagg tgcggtagct
    44281 attttgtgaa aaaccgacgt gtttgataac ttcgaggatt ttatgactgc ttttatcgac
    44341 cagtagaata ttactgtgtt tccccataat ttcaataatc aaggtagcct ggatatggtc
    44401 tccaatctcg tttttattgg aaactgtcat ttccacaata cggtcatttt ccacttgctc
    44461 aatcgactca atcagggccc cctgcaaata ctttctcaaa accatgataa aggtagaagg
    44521 ttgagctgga ttttcaaaag tcgtttgggt cagctgaatg cgtccaaaaa ctggatgggc
    44581 agaaaggagc aggcgatggc tttggcgatt gctgcggatt tgcaagacca actcttgttc
    44641 aaaaggctga ttgattttct ggatgcgacc attcactaat tcgcttcgca attcctcaac
    44701 tatgtggtgt aaaaaaaatc catcaaatga catcgttctc tccttgtgat tgtattccat
    44761 agtattatat caaaaaggta gaataaaatc atggaaatgt ggtataataa agccaagtaa
    44821 agagaaatga gaagcacatg tatattgaaa tggtagatga aactggtcaa gtttcaaaag
    44881 aaatgttgca acaaacccaa gaaattttgg aatttgcagc ccaaaaatta ggaaaagaag
    44941 acaaggagat ggcagtcact tttgtgacca atgagcgtag tcatgaactt aatctggagt
    45001 accgtgacac cgaccgtccg acagatgtca tcagccttga gtataaacca gaattggaaa
    45061 ttgcctttga cgaagaggat ttgcttgaaa atccagaatt ggcagagatg atgtctgagt
    45121 ttgatgccta tattggggaa ttgttcatct ctatcgataa ggctcatgag caggccgaag
    45181 aatatggtca cagctttgag cgtgagatgg gcttcttggc agtacacggc tttttacata
    45241 ttaacggcta tgatcactac actccggaag aagaagcgga gatgttcggt ttacaagaag
    45301 aaattttgac agcctatgga ctcacaagac aataaacgaa aatggaaaaa tcgtgacctg
    45361 atatccagtt tagaatttgc catcacaggg atttttactg ctatcaagga agaacgaaat
    45421 atgcgaaaac atgcagtgac ggctctagtg gtcatccttg caggttttgt ttttcaggtg
    45481 tcacgaatcg aatggctctt tctcctattg agcattttct tggtagtagc ctttgagatt
    45541 atcaattctg ctatcgaaaa tgtggtggat ttggccagtc actatcactt ttccatgctg
    45601 gctaaaaatg ccaaggatat ggcggctggc gcggtattag tggtttctct tttcgcagcc
    45661 ttaacaggtg cattgatttt tctcccacga atctgggatt tattatttta aacagtaaga
    45721 ggaaattatg acttttaaat caggctttgt agccatttta ggacgtccca atgttgggaa
    45781 gtcaaccttt ttaaatcacg ttatggggca aaagattgcc atcatgagtg acaaggcgca
    45841 gacaacgcgc aataaaatca tgggaattta cacgactgat aaggagcaaa ttgtctttat
    45901 cgacacacca gggattcaca aacctaaaac agctctcgga gatttcatgg ttgagtctgc
    45961 ctacagtacc cttcgcgaag tggacaccgt tcttttcatg gtgcctgctg atgaagcgcg
    46021 tggtaagggg gacgatatga ttatcgagcg tctcaaggct gccaaggttc ctgtgatttt
    46081 ggtggtgaat aaaatcgata aggtccatcc agaccagctc ttgtctcaga ttgatgactt
    46141 ccgtaatcaa atggacttta aggaaattgt tccaatctca gcccttcagg gaaataacgt
    46201 gtctcgtcta gtggatattt tgagtgaaaa tctggatgaa ggtttccaat atttcccgtc
    46261 tgatcaaatc acagaccatc cagaacgttt cttagtttca gaaatggttc gcgagaaagt
    46321 attgcaccta actcgtgaag agattccgca ttctgtagca gtagttgttg actctatgaa
    46381 acgagacgaa gagacagaca aggttcacat ccgtgcaacc atcatggtcg agcgcgatag
    46441 ccaaaaaggg attatcatcg gtaaaggtgg cgctatgctt aagaaaatcg gtagcatggc
    46501 ccgtcgtgat atcgaactca tgctaggaga caaggtcttc ctagaaacct gggtcaaggt
    46561 caagaaaaac tggcgcgata aaaagctaga tttggctgac tttggctata atgaaagaga
    46621 atactaagta gaggtaggct catgcctgct tcttgttttt acagaaggag gacttatgcc
    46681 tgaattacct gaggttgaaa ccgtttgtcg tggcttagaa aaattgatta taggaaagaa
    46741 gatttcgagt atagaaattc gctaccccaa gatgattaag acggatttgg aagagtttca
    46801 aagggaattg cctagtcaga ttatcgagtc aatgggacgt cgtggaaaat atttgctttt
    46861 ttatctgaca gacaaggtct tgatttccca tttgcggatg gagggcaagt atttttacta
    46921 tccagaccaa ggacctgaac gcaagcatgc ccatgttttc tttcattttg aagatggtgg
    46981 cacgcttgtt tatgaggatg ttcgcaagtt tggaaccatg gaactcttgg tgcctgacct
    47041 tttagacgcc tactttattt ctaaaaaatt aggtcctgaa ccaagcgaac aagactttga
    47101 tttacaggtc tttcaagctg cccttgccaa gtccaaaaag cctatcaaat cccatctcct
    47161 agaccagacc ttggtagctg gacttggcaa tatctatgtg gatgaggttc tctggcgagc
    47221 tcaggttcat ccagctagac cttcccagag tttgacagca gaagaagcga ctgccattca
    47281 tgaccagacc attgctgttt tgggccaggc tgttgaaaaa ggcggttcca ccattcggac
    47341 ctataccaat gcctttgggg aagatggaag catgcaggat tttcatcagg tctatgataa
    47401 gactggtcaa gaatgtgtac gctgtggtac catcattgag aaaattcaac taggcggacg
    47461 aggcacccac ttttgtccaa actgtcaaag gagggactga tgagaaaaat catcggaatc
    47521 actgggggaa ttgcctctgg taagtcaact gtgacaaatt ttctaagaca gcaaggcttt
    47581 caagtagtgg atgccgacgc agtcgtccac caactacaga aacctggtgg tcgtctgttt
    47641 gaggctctag tacagcactt tgggcaagaa atcattcttg aaaacggaga actcaatcgc
    47701 cctctcctag ctagtctcat cttttcaaat cctgaagagc aaaaatggtc taagcaaatt
    47761 caaggggaga ttatccgtga ggaactggct actttgagag aacagttggc tcagacagaa
    47821 gagattttct tcatggatat tcccctactt tttgagcagg actacagcga ttggtttgct
    47881 gagacttggt tggtctatgt ggaccgagat gcccaagtag aacgcttaat gaaaagggac
    47941 cagttgtcca aagatgaagc tgagtctcgt ctggcagccc agtggccttt agaaaaaaag
    48001 aaagatttgg ccagccaggt tcttgataat aatggcaatc agaaccagct tcttaatcaa
    48061 gtgcatatcc ttcttgaggg aggtaggcaa gatgacagag attaactgga aggataatct
    48121 gcgcattgcc tggtttggta attttctgac aggagccagt atttctttgg ttgtaccttt
    48181 tatgcccatc ttcgtggaaa atctaggtgt agggagtgag caagtcgctt tttatgcagg
    48241 cttagcaatt tctgtctctg ctatttccgc ggcgctcttt tctcctattt ggggtattct
    48301 tgctgacaaa tacggccgaa aacccatgat gattcgggca ggtcttgcta tgactatcac
    48361 tatgggaggc ttggcctttg tcccaaatat ctattggtta atctttcttc gtttactaaa
    48421 cggtgtattt gcaggttttg ttcctaatgc aacggcactg atagccagtc aggttccaaa
    48481 ggagaaatca ggctctgcct taggtacttt gtctacaggc gtagttgcag gtactctaac
    48541 tggtcccttt attggtggct ttatcgcaga attatttggc attcgtacag ttttcttact
    48601 ggttggtagt tttctatttt tagctgctat tttgactatt tgctttatca aggaagattt
    48661 tcaaccagta gccaaggaaa aggctattcc aacaaaggaa ttgtttactt cagttaaata
    48721 tccctatctt ttgctcaatc tctttttaac cagttttgtc atccaatttt cagctcaatc
    48781 gattggccct attttggctc tttatgtacg cgacttaggg cagacagaga atcttctttt
    48841 tgtctctggt ttgattgtgt ccagtatggg cttttccagc atgatgagtg caggagtcat
    48901 gggcaagcta ggtgacaagg tgggcaatca tcgtctcttg gttgtcgccc agttttattc
    48961 agtcatcatc tatctcctct gtgccaatgc ctctagcccc cttcaactag gactctatcg
    49021 tttcctcttt ggattgggaa ccggtgcctt gattcccggg gttaatgccc tactcagcaa
    49081 aatgactccc aaagccggca tttcgagggt ctttgccttc aatcaggtat tcttttatct
    49141 gggaggtgtt gttggtccca tggcaggttc tgcagtagca ggtcaatttg gctaccatgc
    49201 tgtcttttat gcgacaagcc tttgtgttgc ctttagttgt ctctttaacc tgattcaatt
    49261 tcgaacatta ttaaaagtaa aggaaatcta gtgcgagtaa aaattaatct caaatgctcc
    49321 tcttgtggca gtatcaatta cctaaccagt aaaaattcaa aaacccatcc agacaagatt
    49381 gaggttttaa agtattgtcc caaggaaaga aaagtaaccc tacatcttga atctaagtag
    49441 attttatggt aaaataatag ggattttaag gagtttgata tgtataacct attattaacc
    49501 attttattag tattatctgt tgtgattgtg attgcaattt tcatgcaacc aaccaaaaac
    49561 caatccagca atgtatttga tgccagttca ggtgatttgt ttgaacgcag taaagctcgc
    49621 ggttttgaag ctgtaatgca gcgtttgaca gggattttag tctttttctg gctagccatt
    49681 gccttagcat tgacggtatt atcaagtaga taagaaaata atgggcagga ctaggtcttt
    49741 gcctcttttt atttttaaag gatgtttgag aaggttttac agtaaaagaa aattaaaaaa
    49801 tctagaaaga aaatatgaaa gatagaataa aagaatattt acaagacaag ggaaaggtga
    49861 ctgttaatga tttggctcag gctttgggaa aagacagttc caaggatttt cgtgagttga
    49921 ttaaaacctt gtccttaatg gaaagaaagc accagattcg ctttgaagaa gatggcagtc
    49981 tgaccttgga agccaagaaa aaacatgaga ttaccctcaa ggggattttt catgcccata
    50041 aaaatggttt tggctttgtc agcctagaag gggaagagga cgaccttttt gtagggaaaa
    50101 atgatgtcaa ctatgctatt gatggtgata ccgttgaggt cgtcatcaag aaagtcgctg
    50161 accgcaataa gggaacagca gcagaagcca aaattattga tatcctagaa cacagtttaa
    50221 caacagttgt cgggcaaatc gttctggatc agggaaagcc taagtatgtt ggctatattc
    50281 gttcaaaaaa tcagaaaatt agtcaaccga tttatgttaa gaaaccagcc ctaaaattag
    50341 aaggaacaga agttctcaaa gtctttatcg ataaatatcc aagcaagaaa catgatttct
    50401 ttgtcgcgag tgttctcgat gtggtgggac actcaacgga tgtcggaatt gatgttcttg
    50461 aggtcttgga atcaatggac attgtatccg agtttccaga agctgttgtt aaggaagcag
    50521 aaagtgtgcc tgatgctccg tctcaaaagg atatggaagg ccgtctggat ctaagagatg
    50581 aaattacctt taccattgac ggtgcggatg ccaaggactt ggacgatgca gtgcatatca
    50641 aggctctgaa aaatggcaat ttggagcttg gggttcacat cgcagatgtt tcttattatg
    50701 tgaccgaggt gtctgccctt gacaaggaag cccttaaccg tgcgacttct gtttacgtga
    50761 cagaccgagt ggtgccaatg cttccagaac gactatcaaa tggcatctgc tctctcaatc
    50821 cccaagttga ccgcctgacc cagtctgcta ttatggagat tgataaacat ggtcgtgtgg
    50881 tcaactatac cattacacaa acagttatca agaccagttt tcgtatgacc tatagcgatg
    50941 tcaatgatat cctagctggc gatgaagaaa agagaaaaga atatcataaa attgtatcaa
    51001 gtatcgaact catggccaag cttcatgaaa ctttagaaaa catgcgtgtg aaacgtggag
    51061 ctctcaattt tgataccaat gaagcgaaga ttttagtgga taaacaaggt aagcctgttg
    51121 atatcgttct tcggcagcgt ggcattgccg agcggatgat tgagtctttt atgttgatgg
    51181 ctaatgaaac agttgccgaa catttcagca agttggattt gccttttatc tatcgaattc
    51241 acgaggagcc taaggctgaa aaggttcaga agtttattga ttatgcttcg agttttggct
    51301 tgcgtattta tgggactgcc agtgagatta gtcaggaggc acttcaagac atcatgcgtg
    51361 ctgttgaggg agaaccttat gcagatgtat tgtccatgat gcttcttcgc tctatgcagc
    51421 aggctcgtta ttcggagcac aatcacggcc actatggact agctgctgac tattatactc
    51481 actttaccag tccaattcgt cgttatccag accttcttgt tcaccgtatg attcgggatt
    51541 acggccgttc taaggaaata gcagagcatt ttgaacaagt gattccagag attgcgaccc
    51601 agtcttccaa ccgtgaacgt cgtgccatag aagctgagcg tgaagtcgaa gccatgaaaa
    51661 aggctgagta tatggaagaa tacgtgggtg aagagtatga tgcagttgta tcaagtattg
    51721 tcaaattcgg tctctttgtc gaattgccaa acacagttga aggcttgatt cacatcacta
    51781 atctacctga attttatcat ttcaatgagc gtgatttgac tcttcgtgga gaaaaatcag
    51841 gtatcacttt ccgagtgggt cagcagatcc gtatccgtgt tgaaagagcg gataaaatga
    51901 ctggagagat tgatttttca ttcgtaccta gtgagtttga tgtgattgaa aaaggcttga
    51961 aacagtctag tcgtagtggc agagggcgtg gttcaaatcg tcgttcggat aagaaggaag
    52021 acaagagaaa atcaggacgc tcaaatgata agcgtaagca ttcacaaaaa gacaagaaga
    52081 aaaaaggaaa gaaacctttt tacaaggaag tagctaagaa aggagccaag catggcaaag
    52141 ggcgagggaa aggtcgtcgc acaaaataaa aaggcacgcc acgactatac aatcgtagat
    52201 acgctagagg cagggatggt cctgactgga actgaaatca agagtgtacg agctgctcga
    52261 attaatctca aggatggctt tgctcaagtg aaaaatggag aagtttggct gagcaatgtt
    52321 catatcgcgc cttacgaaga gggcaatatc tggaaccagg aaccagaacg tcgtcgtaaa
    52381 ctcctgctct ataaaaagca aattcaaaaa ttggaacaag agaccaaagg gacaggaatg
    52441 accttagttc cccttaaggt ctatataaaa gatggctacg ctaagcttct tttaggactt
    52501 gccaaaggga agcatgacta tgacaaacgg gagtctatca aacgtcgtga gcaaaatcga
    52561 gatatcgcgc gtgtgatgaa agctgttaat cagcgataaa aagaggaatt gaaaatggaa
    52621 aaattagttg cctataagcg catgcctttg tggaataaac aaacaatgcc tgaagctgtt
    52681 cagcaaaagc acaatacaaa agttgggact tgggggaaaa ttactgtctt gaagggagct
    52741 atcaagttta ttgaattgac agaagaaggg gaagttctag ctgaacacct ctttgaagca
    52801 ggggcagaca atccaatggc ccaacctcaa gcctggcacc gagtggaagc tgccacagat
    52861 gatgtggaat ggtacttgga attttattgt aaacctgagg attattttgc taaaaaatac
    52921 aataccaatc ctgttcattc agaggtccta gaggccatgc agacagtgaa acaagggaaa
    52981 gctttggatt tgggttgtgg tcaggggcgt aattctcttt ttctagccca gcaagatttt
    53041 gatgtgacgg ctgtagatca aaatggacta gctcttgaaa tcttgcaaag cattgtggag
    53101 caggaagatt tggacatgcc tgttggcctt tacgatatca attcagctag cattgaacaa
    53161 gaatatgatt ttatcgtttc aacagttgtt ctcatgtttc tacaagcgga ccgcattcca
    53221 gctattattc aaaatatgca ggagaaaacc agtgttggtg gttacaacct tatcgtttgt
    53281 gccatggaca cggaggatta tccttgctcg gttaacttcc cattcacctt taaagaagga
    53341 gaactggcag actattacaa ggattgggaa ttggttaagt acaatgaaaa tccaggccat
    53401 ttgcatcgtc gcgatgagaa tggcaatcgt attcaactac gctttgcgac cttactagct
    53461 aagaaaatca agtaaacaca catgaagatt aggaattttc ctgatctttt ttctttttta
    53521 cgaatgatat agaaaaggag ggaattcatg tttgttgcga gagatgctag gggagaattg
    53581 gtaaatgtgt tagaggataa acttgagaag caagcataca cctgcccagc ttgtggaggc
    53641 cagctccatt tgcgtcaagg accaagtgta cggacgcatt ttgcccataa atccttaaaa
    53701 gactgtgatt ttttctttga aaatgaaagt ccagaacacc tggccaataa ggaatccctc
    53761 tatcactggt tgaaaaaaga gacaaaggtt caattagagt acccgctttc agaacttaaa
    53821 cagattgcgg atgtatttgt aaatggcaat ctagatctag aagttcagtg tagtcccttg
    53881 cctcagaaag tccttaaaga gcgaagtgag ggatatcgta gtcagggtta ccaagtactg
    53941 tggttgctgg gtcaaaaact gtggctcaag gagcgtttga ctcgtctaca gcaaggtttt
    54001 ctttatttca gtcaaaacat gggcttttat gtttgggaat tagacaagga aaaacaagtt
    54061 ttaagactca aatacctgat ttaccaggat ctccgcggta aactccatta tcaaatcaag
    54121 gaattttcct atggtcaagg tagtttattg gaaatattgc gtcttcccta taagagacaa
    54181 aaaatatctc attttacagt ttctgaggac aaggacatct gtcgctatat ccggcaacaa
    54241 ctttattatc aaaatctctt ttggatgaaa gaacaagcag aagcctatca aaagggagaa
    54301 aatatcctga cttatggact gaaagaatgg tatccacaaa ttcgaccaat agtgggcaaa
    54361 tttttccaga ttgaacaaga cttgactaac tattatcagc acttttatac ctattaccaa
    54421 aaaaatcctc aaaatgattg gcaaaagctt tatccaccag ccttttatca gcaatatttc
    54481 ttgaaaaata tggtaaaata gaaaggatgg aggaatctaa tggtattaca aagaaatgaa
    54541 ataaatgaaa aagatacatg ggatctatca acgatctacc caactgacca ggcttgggaa
    54601 gaagccttaa aagatttaac agaacaattg gagacagtag cccagtatga aggccatctc
    54661 ttggatagtg cggataacct actagaaatc actgaatttt ctcttgaaat ggaacgccag
    54721 atggagaagc tttacgttta tgctcatatg aagaatgacc aggatacacg tgaagctaag
    54781 tatcaagagt actatgccaa ggccatgaca ttctacagcc agttagacca agccttttca
    54841 ttctatgagc ctgaatttat ggagattagc gaaaagcagt atgctgactt tttagaagct
    54901 caaccaaagc tgcaggttta tcaacactat tttgacaagc tcttgcaagg caaggatcac
    54961 gttctctcac aacgtgaaga agaattattg gctggagctg gagaaatctt tggttcagca
    55021 agtgaaacct tcgctatctt ggacaatgcg gatattgtgt tcccttatgt cctagacgat
    55081 gatggtaaag aagttcagct atctcatggg atttacacac gtttgatgga gtctaaaaaa
    55141 cgtgaggttc gccgtggtgc ctatcaagct ctttatgcga cttacgaaca attccaacac
    55201 acctatgcca aaaccttgca aaccaatgtt aaggtgcaaa attaccgtgc taaagttcgt
    55261 aactacaaga gtgctcgtca tgcagccctc gcagcgaatt ttgttccaga aagtgtttat
    55321 gacaatttgg tagcagcagt tcgcaagcat ttgccactct tacatcgcta tcttgagctt
    55381 cgttcaaaaa tcttggggat ttcagatctc aagatgtacg atgtctacac accgctttca
    55441 tctgttgaat acagttttac ctaccaagaa gccttgaaaa aagcagaaga tgctttggta
    55501 gtcttgggtg aggattactt gagccgtgtt aaacgtgcct tcagcgagcg ttggattgat
    55561 gtttacgaaa atcaaggcaa gcgttcaggt gcctactctg gtggttctta cgataccaat
    55621 gcctttatgc ttctcaactg gcaggacaat ctggacaatc tctttactct tgttcatgaa
    55681 acaggtcaca gtatgcattc aagctatact cgtgaaactc agccttatgt ttacggagat
    55741 tactctatct ttttggctga gattgcctca actaccaatg aaaatatctt gacggagaaa
    55801 ttattggaag aagtggaaga cgacgcaaca cgctttgcta ttctcaataa cttcctagat
    55861 ggtttccgtg gaacagtttt ccgccaaact caatttgctg agtttgaaca cgccattcac
    55921 caagcagatc aaaatgggga ggtcttgaca agcgatttcc taaataaact ctacgcagac
    55981 ttgaaccaag agtattatgg tttgagtaag gaagacaatc ctgaaatcca atacgagtgg
    56041 gctcgcattc cacacttcta ctataactac tatgtatatc aatattcaac tggctttgcg
    56101 gccgcctcag ccttggctga aaaaattgtc catggtagtc aagaagaccg tgaccgctat
    56161 atcgactacc tcaaggcagg taagtcggac tatccactta atgtcatgag aaaagctggt
    56221 gttgatatgg agaaggaaga ctacctcaac gatgcctttg cagtctttga acgccgttta
    56281 aatgagtttg aagcccttgt tgaaaaatta ggattagcat aaaatggttg aatcgtatag
    56341 taagaatgct aaccataaca tgcgtcgtcc tgtcgtcaaa gaagaaattg tagacttgat
    56401 gcgtcagcgt caaaagcaag tcacaggttt cttgaaagaa ttggaagatt ttgcccgcaa
    56461 ggaaaatatt cctattattc cccatgaaac ggttgcttat ttccgttttc ttatggaaac
    56521 catgcagcct aaaaatattc tggaaattgg gacggctatc ggtttttcag ctctcttgat
    56581 ggctgaacat gcgccaaatg ctaagattac aactattgat cgtaatccag aaatgattgg
    56641 ttttgccaag gaaaattttg cccagtttga cagtcgcaag caaatcactc tcctagaggg
    56701 agatgcggtg gatgtcttat ctacactgac agagtcttat gatttcgtct ttatggattc
    56761 tgccaagtct aaatacatcg tctttctgcc agaaatcctc aaacatttgg aagttggtgg
    56821 tgtggttgtc ttggatgata tttttcaagg tggtgatgtt gccaaggata ttatggaagt
    56881 ccgtcgtggt cagcgaacca tttatcgagg ccttcaaaaa ttatttgatg caaccttaga
    56941 caatccagaa ctcaccgcaa cattagtgcc tttaggagat ggtattctca tgcttcgtaa
    57001 aaaggtagca gatgttcaac tgtctgaaag cgaatgattt tcagaaaaat ttaagaaaaa
    57061 atagtaaaat agatagggta acacttatct caaaggagta gacatgaaga aaaaactatt
    57121 ggcaggtgcc atcacactat tatcagtagc aactttagca gcttgttcga aagggtcaga
    57181 aggggcagac cttatcagca tgaaagggga tgtcatcaca gaacatcaat tttatgagca
    57241 agtgaaaagc aacccttcag cccaacaagt cttgttaaat atgaccatcc aaaaagtttt
    57301 tgaaaaacaa tatggctcag agcttgatga taaagaggtt gatgatacta ttgccgaaga
    57361 aaaaaaacaa tatggcgaaa actaccaacg tgtcttgtca caagcaggta tgactcttga
    57421 aacacgtaaa gctcaaattc gtacaagtaa attagttgag ttggcagtta agaaggtagc
    57481 agaagctgaa ttgacagatg aagcctataa gaaagccttt gatgagtaca ctccagatgt
    57541 aacggctcaa atcatccgtc ttaataatga agataaggcc aaagaagttc tcgaaaaagc
    57601 caaggcagaa ggtgctgatt ttgctcaatt agccaaagat aattcaactg atgaaaaaac
    57661 aaaagaaaat ggtggagaaa ttacctttga ttctgcttca acagaagtac ctgagcaagt
    57721 caaaaaagcc gctttcgctt tagatgtgga tggtgtttct gatgtgatta cagcaactgg
    57781 cacacaagcc tacagtagcc aatattacat tgtaaaactc actaagaaaa cagaaaaatc
    57841 atctaatatt gatgactaca aagaaaaatt aaaaactgtt atcttgactc aaaaacaaaa
    57901 tgattcaaca tttgttcaaa gcattatcgg aaaagaattg caagcagcca atatcaaggt
    57961 taaggaccaa gccttccaaa atatctttac ccaatatatc ggtggtggag attcaagctc
    58021 aagcagtagt acatcaaacg aatagtccaa atcaatgaat cagggaaaaa actcgacttc
    58081 aggaaaaaat gaagcaaaca ttcccacaat aaaacgcgta gtacaaggtt tgtactgacc
    58141 cccaaaagtt agacaaataa tttatccgaa ggatttagtt ctgtattgca cagggctaag
    58201 tccttttagt tttaccttaa ttctcttgtt gttgtaataa tcaatatagt ctataatggc
    58261 ttgttccaat tgattaagtg atttaaatgt tttctcatag ccataaaaca tttcggattt
    58321 taaaatacca aagaaagatt ccatcctacc gttgtcttgg ctgtttccct tgcgtgacat
    58381 agatgcttga attcccttac tctctaggaa ccgatgataa gaatcgtgtt ggtattgcca
    58441 gtcttggtca ctatggagaa tcgtattctc gtagtgcttc tctttgaatg cctgttccaa
    58501 cattaacgat caatcaattt aatcatgtac ctaagattag aattgtttat cccaaattta
    58561 tttgaaagct tc
//
LOCUS       DAVHSI010000011        57417 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.011, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000011 DAVHSI010000000
VERSION     DAVHSI010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.011"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(275..493)
                     /locus_tag="VVR21_000736"
     CDS             complement(275..493)
                     /locus_tag="VVR21_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU6054655.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            651..725
                     /locus_tag="VVR21_000737"
                     /pseudo
     CDS             651..725
                     /locus_tag="VVR21_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(952..1110)
                     /locus_tag="VVR21_000738"
                     /pseudo
     CDS             complement(952..1110)
                     /locus_tag="VVR21_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1488..2177)
                     /gene="rplA"
                     /locus_tag="VVR21_000739"
     CDS             complement(1488..2177)
                     /gene="rplA"
                     /locus_tag="VVR21_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU6054656.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2385..2810)
                     /gene="rplK"
                     /locus_tag="VVR21_000740"
     CDS             complement(2385..2810)
                     /gene="rplK"
                     /locus_tag="VVR21_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU6054657.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2936..3016
                     /locus_tag="VVR21_000741"
                     /pseudo
     CDS             2936..3016
                     /locus_tag="VVR21_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3119..3835)
                     /locus_tag="VVR21_000742"
     CDS             complement(3119..3835)
                     /locus_tag="VVR21_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEU6054658.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAAGYPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3853..4314)
                     /locus_tag="VVR21_000743"
     CDS             complement(3853..4314)
                     /locus_tag="VVR21_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6054659.1"
                     /translation="MCLICQRIELIKAGENPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KEHVTELHQMENSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKGHGLNGRGPVWWVPWEEMAAEDCQVQSPEREEMIKILSHELEKHLA"
     gene            complement(4316..5353)
                     /locus_tag="VVR21_000744"
     CDS             complement(4316..5353)
                     /locus_tag="VVR21_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU6054660.1"
                     /translation="MNQTVNYIKELTAIASPTGFTREISEYLVHTLEELGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIDLPMTTHFAFSVFEE
                     VGHGANSNIPEEVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(5451..6776)
                     /gene="brnQ"
                     /locus_tag="VVR21_000745"
     CDS             complement(5451..6776)
                     /gene="brnQ"
                     /locus_tag="VVR21_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU6054661.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6947..7039)
                     /locus_tag="VVR21_000746"
     CDS             complement(6947..7039)
                     /locus_tag="VVR21_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6054662.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7082..7234)
                     /locus_tag="VVR21_000747"
     CDS             complement(7082..7234)
                     /locus_tag="VVR21_000747"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU6054663.1"
                     /translation="MKEIAFDAFYQLYQNDQFSLVDVREVDEFAALHLEGAYNLPLSQ
                     LADSYD"
     gene            complement(7394..7972)
                     /locus_tag="VVR21_000748"
     CDS             complement(7394..7972)
                     /locus_tag="VVR21_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU6054664.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8026..9426)
                     /gene="pepV"
                     /locus_tag="VVR21_000749"
     CDS             complement(8026..9426)
                     /gene="pepV"
                     /locus_tag="VVR21_000749"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU6054665.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9439..10044)
                     /locus_tag="VVR21_000750"
     CDS             complement(9439..10044)
                     /locus_tag="VVR21_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU6054666.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            10215..11015
                     /locus_tag="VVR21_000751"
     CDS             10215..11015
                     /locus_tag="VVR21_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6054667.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVVATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11197..12030)
                     /locus_tag="VVR21_000752"
     CDS             complement(11197..12030)
                     /locus_tag="VVR21_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU6054668.1"
                     /translation="MNHKIAILSDIHGNVTALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNILFRKV
                     AYDYEAELEFAKSKGLPFIEMYEELRREDNYQRHNLELLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(12020..13864)
                     /gene="uvrC"
                     /locus_tag="VVR21_000753"
     CDS             complement(12020..13864)
                     /gene="uvrC"
                     /locus_tag="VVR21_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU6054669.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGHDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEAHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNKP"
     gene            complement(13903..14604)
                     /locus_tag="VVR21_000754"
     CDS             complement(13903..14604)
                     /locus_tag="VVR21_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU6054670.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14683..15915)
                     /gene="murN"
                     /locus_tag="VVR21_000755"
     CDS             complement(14683..15915)
                     /gene="murN"
                     /locus_tag="VVR21_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU6054671.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFCYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15920..17140)
                     /gene="murM"
                     /locus_tag="VVR21_000756"
     CDS             complement(15920..17140)
                     /gene="murM"
                     /locus_tag="VVR21_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU6054672.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRSLEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17252..18031)
                     /locus_tag="VVR21_000757"
     CDS             complement(17252..18031)
                     /locus_tag="VVR21_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU6054673.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKIFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18100..19761)
                     /locus_tag="VVR21_000758"
     CDS             complement(18100..19761)
                     /locus_tag="VVR21_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6054674.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19936..22158)
                     /gene="recJ"
                     /locus_tag="VVR21_000759"
     CDS             complement(19936..22158)
                     /gene="recJ"
                     /locus_tag="VVR21_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU6054675.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEYLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVTGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22435..23193
                     /locus_tag="VVR21_000760"
     CDS             22435..23193
                     /locus_tag="VVR21_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6054676.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LSPIKVLGIDKKEAEKTAQKYLEFVNIWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            23233..23997
                     /locus_tag="VVR21_000761"
     CDS             23233..23997
                     /locus_tag="VVR21_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6054677.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24010..24687
                     /locus_tag="VVR21_000762"
     CDS             24010..24687
                     /locus_tag="VVR21_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6054678.1"
                     /translation="MTDLSSWTAYFQDFEQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24697..25356
                     /locus_tag="VVR21_000763"
     CDS             24697..25356
                     /locus_tag="VVR21_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6054679.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVHNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYKAGMSQGFTSAQILYYIILPQASRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25651..26841
                     /locus_tag="VVR21_000764"
     CDS             25651..26841
                     /locus_tag="VVR21_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU6054680.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLCRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27162..28043)
                     /locus_tag="VVR21_000765"
     CDS             complement(27162..28043)
                     /locus_tag="VVR21_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU6054681.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28184..29512)
                     /gene="vncS"
                     /locus_tag="VVR21_000766"
     CDS             complement(28184..29512)
                     /gene="vncS"
                     /locus_tag="VVR21_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU6054682.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29509..30165)
                     /gene="vncR"
                     /locus_tag="VVR21_000767"
     CDS             complement(29509..30165)
                     /gene="vncR"
                     /locus_tag="VVR21_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU6054683.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30214..30300)
                     /gene="pep27"
                     /locus_tag="VVR21_000768"
     CDS             complement(30214..30300)
                     /gene="pep27"
                     /locus_tag="VVR21_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU6054684.1"
                     /translation="MYEKGFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30476..31855)
                     /gene="vex3"
                     /locus_tag="VVR21_000769"
     CDS             complement(30476..31855)
                     /gene="vex3"
                     /locus_tag="VVR21_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU6054685.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31907..32554)
                     /gene="vex2"
                     /locus_tag="VVR21_000770"
     CDS             complement(31907..32554)
                     /gene="vex2"
                     /locus_tag="VVR21_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU6054686.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32567..33844)
                     /locus_tag="VVR21_000771"
     CDS             complement(32567..33844)
                     /locus_tag="VVR21_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054687.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(34200..34370)
                     /locus_tag="VVR21_000772"
                     /pseudo
     CDS             complement(34200..34370)
                     /locus_tag="VVR21_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(34513..35112)
                     /locus_tag="VVR21_000773"
     CDS             complement(34513..35112)
                     /locus_tag="VVR21_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054688.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(35249..36133)
                     /locus_tag="VVR21_000774"
     CDS             complement(35249..36133)
                     /locus_tag="VVR21_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU6054689.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGVQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(36137..36523)
                     /locus_tag="VVR21_000775"
     CDS             complement(36137..36523)
                     /locus_tag="VVR21_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU6054690.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(36516..37859)
                     /locus_tag="VVR21_000776"
     CDS             complement(36516..37859)
                     /locus_tag="VVR21_000776"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU6054691.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(37946..38830)
                     /locus_tag="VVR21_000777"
     CDS             complement(37946..38830)
                     /locus_tag="VVR21_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054692.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(38842..39459)
                     /gene="cysE"
                     /locus_tag="VVR21_000778"
     CDS             complement(38842..39459)
                     /gene="cysE"
                     /locus_tag="VVR21_000778"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU6054693.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(39475..41688)
                     /gene="pnp"
                     /locus_tag="VVR21_000779"
     CDS             complement(39475..41688)
                     /gene="pnp"
                     /locus_tag="VVR21_000779"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU6054694.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(42247..43113)
                     /gene="metF"
                     /locus_tag="VVR21_000780"
     CDS             complement(42247..43113)
                     /gene="metF"
                     /locus_tag="VVR21_000780"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU6054695.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(43177..45426)
                     /gene="metE"
                     /locus_tag="VVR21_000781"
     CDS             complement(43177..45426)
                     /gene="metE"
                     /locus_tag="VVR21_000781"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU6054696.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEVAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(45686..45952)
                     /locus_tag="VVR21_000782"
     CDS             complement(45686..45952)
                     /locus_tag="VVR21_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054697.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            complement(46078..46523)
                     /locus_tag="VVR21_000783"
                     /pseudo
     CDS             complement(46078..46523)
                     /locus_tag="VVR21_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            46679..47680
                     /locus_tag="VVR21_000784"
     CDS             46679..47680
                     /locus_tag="VVR21_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6054698.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYNKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATKIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFKRGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(47748..50153)
                     /locus_tag="VVR21_000785"
     CDS             complement(47748..50153)
                     /locus_tag="VVR21_000785"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU6054699.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFARLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPAAPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(50230..50739)
                     /locus_tag="VVR21_000786"
     CDS             complement(50230..50739)
                     /locus_tag="VVR21_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054700.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(50739..51785)
                     /gene="pheS"
                     /locus_tag="VVR21_000787"
     CDS             complement(50739..51785)
                     /gene="pheS"
                     /locus_tag="VVR21_000787"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU6054701.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(52377..53792)
                     /locus_tag="VVR21_000788"
     CDS             complement(52377..53792)
                     /locus_tag="VVR21_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6054702.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDKEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLKRYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(53805..55643)
                     /locus_tag="VVR21_000789"
     CDS             complement(53805..55643)
                     /locus_tag="VVR21_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6054703.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEVGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(55661..56500)
                     /locus_tag="VVR21_000790"
     CDS             complement(55661..56500)
                     /locus_tag="VVR21_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU6054704.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(56801..56983)
                     /locus_tag="VVR21_000791"
     CDS             complement(56801..56983)
                     /locus_tag="VVR21_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6054705.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGEVDEMTIL
                     RLESASIVSELVAGLR"
     gene            57042..57417
                     /locus_tag="VVR21_000792"
                     /pseudo
     CDS             57042..57417
                     /locus_tag="VVR21_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        16535 a        12873 c        10486 g        17523 t
ORIGIN      
        1 ataaatgttt tagcaattgt ttcgtactat tttagattca gtctactata cataaactaa
       61 cctcctcatt attagcaagg cttctactga ttataaccta attcttagac tacttcaaga
      121 ctaactgtcc aataataatc tacagataaa tcatccactc ttaatcaaat tttattcaat
      181 ccatctactc attcccaaaa ggttgctgta taatgcaaga catttttctt actgctttta
      241 cttttcctta ccctcaattt agtgagctaa taaattattc ttcttcaaaa ggttgagatt
      301 tatctagtaa ctctaaaaca ttaatggtag gtagcaacat tgcttcactg ctatcaattg
      361 ccgaaactat tgaaacaata gaacgtaaat aaggataaag aatagcagta ccatttacgt
      421 atagaatatc ggtgatattt tcatctatat ttatttcaaa atatcctatt acagttacag
      481 atattttttt catggcatct ttgtcaacta aagaaacact aagttttacg gctccatgac
      541 tataatcatc tgtatgacca accttaacta tgggatataa tatatcgaag gtaaatgtga
      601 acaaactgat taggaaattt aaaccaactt ctaacaatgt gttatactca atgaaaacca
      661 aagagcaaac taggaaacta gcctcaggtt gctcaaaaca ctgttttgag gttgtagatg
      721 gaactgacgt agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca
      781 gtaaccatac gcacggcaag gcgacattga cgtggtttga agagattttc gaagagtatt
      841 agaaagctcg atggactatt ccagattcat tccactagat ttcgaaatcg agtaggggat
      901 aatctctagc ccctctcaca ccaccgtacg tgtcgttcgg catacggcgg ttcaactaac
      961 ttttaacgca tgtcgttcaa ggtaataatc caaacacgaa accagtccac gtttttcaag
     1021 gactggtttt gatatagcac gtttaagtac cgacttctga gctactaatt gatagtggtc
     1081 cccccaccca gataccttat ccgctatata ggccttatta tcacgttcct gttcgtagag
     1141 ccacgatttc gctatctctt cctctgacga ttcttatttc cagcgtcaga cttaaaacgg
     1201 tctatcccca gaccgtttta atccgctacc tcacgatagt cagacttggg aatcgctatt
     1261 gggttcaccg gtagcaggtg cccaccgagg acttacacct caaatatata ataaaatgaa
     1321 ataagaacag gacgaatcga tcaggacagt caaatcaatt tctaacaatg ttttagaagt
     1381 agatgtgtac tattctagtt tcaatctact atacaacatg cccgtcgtac atcaaaaaaa
     1441 gttgagacat agcgtcttca acttttttac attactttaa ctactgatta aagtgagttt
     1501 acgtcaactt tgataccaac accttgagta gttgtgatag tcaagtttgt tacgtaagtt
     1561 cctttagctg tagctggttt tgctttttgg attgtttcgt tgaaagcttt aaagttttca
     1621 accaattttt cagcttcaaa tgatacttta ccgatgattg cttgaacgtt acctgcacgg
     1681 tcagcacggt aagtgatttt accaccttta gactcttcaa ctgctttagc aacatccatt
     1741 gttacagtac cagttttagg gtttggcatc aagttacgtg gtccaaggac acgtccaaga
     1801 cgtccaacaa gagccatcat atcaggtgta gcgataacta cgtcgaagtc caaccaaccg
     1861 tcgttgattt tagcaacaag gtcatcttca ccaacaaagt ctgcaccagc agcttttgct
     1921 tcttcagctt ttgcaccacg tgcgaaaaca agaacacgtg aagttttacc agtaccgttt
     1981 ggcaatacca ttgctccacg gatttgttgg tcagcttttt taacgtcgat gttcaagttg
     2041 taagcaactt ctacagttgc atcaaatttt gcaaagttag tttcttttgc aagtgctaca
     2101 gcttcttcta cactgtatgc ttttgtgctg tcgattttct caagagcagc acgaagttgt
     2161 ttgctttttt tagccatttt ctattctcct tgtaagtggt tcaatcgatt ttcatctccc
     2221 acgtcacttc tcgaaatgat gaagtcttgc gggttttcag tctactattt ttctcttcct
     2281 acggccttaa gctcccttgc tgtacccaag tacaagcctc agtcacttgc ctagtatgaa
     2341 aagcaactaa tagactgctg tgagattttc tactgtgtta ttgattagtc aacaacagtg
     2401 aatcccatag aacgagcagt accttcgatc atacgcattg cagactctac gtttgctgcg
     2461 ttcaaatctg gcatcttagt ttctgcaatt tcttgtactt gtgcacgagt aactgtagca
     2521 actttagttt tattaggtgt acctgatcct ttttcaacac ctgcagcttt tttcaaaaga
     2581 acagcagctg gtggtgtttt cgtaacgaaa gtaaatgatt tatcttcgta aactgagata
     2641 acaactggaa tgatcatacc agcttggtca gctgtacgag cgttgaactc ttttgtgaat
     2701 cccatgatgt tgataccagc ttgaccaaga gcaggtccaa ccggtggagc tggtgtagct
     2761 ttaccagcag ggatttgcaa ttttacaagt ttttcgactt ttttagccat ttttaaatcc
     2821 tcctttgtgg ttttggcggt aattagagat ttttacctcc cacaagtatg tttttcacat
     2881 acccatccat tatacactat ttatctggaa ttgcaagaga aaagtttatt ttttgtactc
     2941 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tcctcaaagt acagctttga
     3001 ggttgcagat aaaactgacg aagtcagctc aaaacactgt tttgaggttg tgaatagaac
     3061 cgacgtagtc agtaggtaag gcgacgctga cgtggtttga agagattttc gaagagtatt
     3121 aatcgacgta gtctccgcct tcaaagccat agtattcttc caaactgaga ccacttgcag
     3181 caatttcttt agcttctttt cctacataac gcaggtgcca ttcctcagcc atatagcctg
     3241 tttccttttc cttgcctttg agataacgga caacaaagcc ataatcagct gcatgatcca
     3301 agagccattg ggctgctttt tcttctgtca ccaaatcacc atcagtccca atcacatcaa
     3361 aggccaagcc tgtctggtgt tcgctatagc caggacgggc agagtaacgg tcagctgctg
     3421 cctttccatc ttggttgaca taatcttgat agagcttggt ctgagtttca taacttctaa
     3481 aaccactgta gtgatcgctg attgggtagc cagctgcttg cattgctgca atgagtttca
     3541 gcaactctgc cttggctgtt ggattttctc ctggattgta gtcttttgac aaaggataac
     3601 gtttattagc taggataatt tcatcgtatt tcccttgaat actataatag ctccctttat
     3661 tgctaacttc tgcctttttc tgactagaag cttgagattt gctgcctaca gttccttccg
     3721 gttgactgct ttgctccgtc ttttgagtat tttcttcaac tttcgttttt tcttgcgaac
     3781 aagctgcaag agtcaatgct agtaaaccag ataaaatgac atatcttttt ttcatttctt
     3841 tcttcctctc tcttaggcca aatgcttctc caattcatga gataagattt taatcatctc
     3901 ttcccgctct ggcgattgca cttggcaatc ttctgctgcc atttcttccc agggcaccca
     3961 ccagactggg ccacggccat taagtccgtg ccctttcata tcacctgctc ttcgcggaaa
     4021 aagatgccaa tgagcgtggg catcgccatt tcctaggagt tcaatattca tcttttcagc
     4081 ctcaaatgct ttggcgactg cttcttgaac caaactcatt tcctctaaaa agcgaagttt
     4141 tacagaattc tccatttggt ggagttctgt aacatgttct tttgctaaaa ataaggtata
     4201 gcccttaaag tattggtggt ctccaataac tacatagccc gtttctagtt ctttgacaaa
     4261 gtagggattt tctccagctt tgatgagttc aattctttga cagattaagc acattctatg
     4321 ataccgcctc actcttgaga taggcatcta ccatacgctc agtcgccact actgaatcaa
     4381 tgtgtgtgcg ctcataagag tgactggact cgattcccgc tccaagaagt gcatgcttga
     4441 cctctgcacc tgctgacatc gctgctgaag cgtccgatcc ataaaatgga tagatatcca
     4501 gcttaaatgg aatatcttgc tctttcgcca aagctactaa gtgttgacgg aagtcatagt
     4561 gataaggacc ggaagcatcc ttgacacaga tagatactgt gtactcatcc gtctgttggt
     4621 catcgcccat agctcccata tccacagcca gatattctac tacctcttct ggaatatttg
     4681 aattggcacc atgccccact tcttcaaaca ctgaaaaagc aaagtgtgtc gtcatcggca
     4741 agtcaattcc ttcttcttta taaactcgaa ggagattgag caaaatggct gcactgactt
     4801 tgtcatccaa gtggcgagac ttgataaaac cagtttccgt cacaactgtt cgcggatcaa
     4861 aactaataaa gtcaccaacc tcaataccca aggcacgtgt ttctttttca ttggtcactt
     4921 tttcgtctaa acgcacttcc atattgtcct gagtgcgttc agcagttcct gcatctttgt
     4981 agacatggca agatgtctgg tggataagga tagttccaga taccgtttta cctgtactag
     5041 ccacatgaac ggtacagttt tctccctcaa tcatgttcca aggaaaacca ccgatacggt
     5101 ccaatttgag acgtccgtca ggtttgacag cacgtacaat ggctccgagt gtatccacat
     5161 gggcggttac atagcgatgt tgttcatcat tttgaccttt aatggtcaca ttgacaccgc
     5221 ccttggctgt acgaaccggc tggtaaccaa gttcttctaa agtatggact aggtattctg
     5281 aaatctcacg agtaaagccc gttggagatg caatagcggt taattctttg atatagttta
     5341 cagtttgatt catttcttca cctctttcgc tacctattat aacacattta tcatcggata
     5401 aaaaaagaaa atcactcctg tagacttggc tacaaaagtg atttaagtga ttattccatt
     5461 tcaaaaacat cgctttcttg cttgtttggt agaaccaatg agagcaagat tccaacaatg
     5521 gctggcacca accatgggag agatgccttg gcaaaaggaa gaacgctaac aagatttgca
     5581 agaaactcaa ccttaaacga gcttcctagt acgcttgcaa tggcaataac tgtaaccaca
     5641 gcaattgtca actgcatacc tggttttgaa agggcaacaa atttgttgac aatgacaatc
     5701 ataacgatag caatcgtgat tgggtacaag ataaccagta ctggaattga gtacttgata
     5761 atcgcatcaa gacccaaatt ggcaatagca aatccaatca aggtaaaggc tgtcgcataa
     5821 accttgtagc tgatttgtgg gaagcgctca ttaaagaact cagctgttga cacaatcaaa
     5881 ccaacagtcg ttgtgaagca ggttacggta accatagctg caaggaagag ttgagctgtt
     5941 gagccaaaga tttcttgagt ggcttgtgac aagatgtaaa cacctggtgt tccacccttc
     6001 atcgcttcag ctggtactgg gaaatgattt ccaagaaaac ctaaaccgat gtaaagagcg
     6061 ctgaaggcaa gggcaacaac gataccaaca acccaaatag ttgaaatgta ttctttctta
     6121 cttgaaaatc caagttgttt caaggtttga actgcgatta cgctaaaggc cactgaggca
     6181 agggcgtcca aggtattgta accttctagg aaacctgtac caaaggcaga agcttgataa
     6241 gcagctgaag cagcttgagg acttgttcca ccatatttga tagctcccag aacgaccaag
     6301 ataacaatca aaattgcaaa gactggcgtt aaaatacgtc caatgcggtc taagattttt
     6361 gatggattaa gcgaaatcaa ataggctgcc gcaaaataca gaaccgtaaa tacaatcaag
     6421 ccaagtcctt tatttgcatc cgacaaaagg gggctaatcc ctacttcgta agctgttgta
     6481 gcagtacgtg gggtagcaaa gaatggaccg attgacaagt aaagaactga gaggtaaaga
     6541 gtcgcaaacc aaggcgctat cttcgttgaa atctcgtaga tatatccttt aggatttagc
     6601 gttccaataa taagggtcaa gacggcgata ccaacgcctg aaaagacaaa acctgcgatg
     6661 gcaggaagaa aatgttctcc agatagagca cctagagaag gcggaaaaat caagttcccc
     6721 gcaccaaaaa atattccaaa caggagcaaa cctgttaggg tacctttttt agccataaaa
     6781 atctccttca tatttataaa atactgacct agtataccac gattaggagt ctgaaaaaag
     6841 catcacgagg caaatattaa atgttttcaa ttttcttaaa aataagaatt atctaaaaat
     6901 aaaactctcc tacccagtcc acaccaagta ggagaaatgc aaaattttaa agttcttcaa
     6961 aggctaacat gccaccctgg acattgataa cattataacc ttgttctaat aggaattggc
     7021 aagcacgcgc cgatctcatt ccagatttgc aaataatata atgcaagcga tctttgtcca
     7081 attaatcata actatcagcc aattgactaa gcggtaggtt gtaggcacct tctaaatgaa
     7141 gagctgcaaa ctcatccact tctctcacat ccactagaga aaactgatcg ttttggtaaa
     7201 gctggtaaaa tgcgtcaaag gctatttctt tcattctttt tcttctaata ctcttcgaaa
     7261 atctcttcaa accacgtcag cgtcgcctta ccgtgcgtat gttaccgact tcgtcagttt
     7321 tatctgcaac ttcaaagctg tactttgagc agcctacgac tagcttccta gtttgctctt
     7381 tgattttcat tgactataaa atcgttttaa ttcttttttt caaatctggc actacttctg
     7441 cctcaaacca aggatttttg gccatccaga tttgatttcg tggtgatggg tgaactagcg
     7501 gaaaataggc tggcagatag tctttatagt gtttcaccct ctccgttacc ttcccactga
     7561 ttttctcctg taaatagtag gcttgggcat attgcccaat caagagggtt aactgaatat
     7621 caggcaattc ctgtaagagt tgcggatgcc atttttctgc aaaacctgta cgaggcggaa
     7681 gatcacccga cttgccatgt cctggaaagt agaaatccat aggcaaaaca gcaaaataac
     7741 ctgaattgta aaaggtatct tcatccacac ctagccagtc ccgcaaacgg tcaccacttt
     7801 tatctttcca gtaaaggcct gcttcttgag ttttaagtcc cggagcctga ccgatgatat
     7861 tgatgcgagc agtttttggc gctgcaaaga gaggctcaat gccacgctct gtatagctgg
     7921 cattctgcga atccgccatg atagcctgtt tgattctttc gatttgagac atctactttc
     7981 cctccaaaaa gaagtccaag cataagatct cagacttcta tcgttttatt tgatcaattc
     8041 gtaaatagct tcggcataaa ttgctgctgc tcggaagaga tcgtccaagg caataaattc
     8101 attggcttgg tgcatggtat caattgagtc tgggaacata gcaccatagg caactccgcg
     8161 ctctaacaag cgaccaaagg ttccaccacc gatgacttgt tcatgacctt taaggcctgt
     8221 ttgtttttca tagacattca acaaggtttg cacaagtgga tcttccattg gcacatagtg
     8281 aggggtatga ccatgttctg atagactgac agaagcaact ggcaagtttt ctaggattga
     8341 cttgatttgt tctggacttg ttccttttgg atagcggatg ttaagggcaa tggtattatc
     8401 agcacttgtt tcatcgaagc ggaagacgcc ggcattcata gaaagagcac ccatcttttc
     8461 atccacatga gcaatcttga gattttcacc ctcatgatcg ttcaagagaa ttttacctgc
     8521 gatgtcaagg tagtctttgg ctggaccagc aaagccaaac tggctgagga agagggcaag
     8581 gtaagttgcg ccattgacac ctgaagcagg catagcaccg tgggctgatt taccaatgat
     8641 cgtcaccttg tattggccag cttcttcttg gagttctcct ctaagtttgt gttctgcaac
     8701 aaaggcatct agtttagctt gcaagtctgt caagtcacct gaaacgactg ctgttgctga
     8761 ttctggtacc atattttcac gtaaaccacc tgtaaagctg tgaagacggg ctgcacctgt
     8821 attttcacct gcaaagtgga ggtattccgt gatatttcct ttttcaccat tgatgattgg
     8881 aaattcagca tctggagaga aaccaaagtc tggcttcgca agtcctacgt gctcaaagta
     8941 gtagtccatg tctgcccagc ctgattcttc gtctgttcca acgatgaagc gaactttctt
     9001 agaagttgga agacccaatt ctttgatgat tttcaaacca tagtaacaag ctgttgtagg
     9061 acccttatcg tccgaagccc cgcgcgcata aaggcgacca tctttgatag ttggtgtgta
     9121 aggatctgta tcccaaccgc taccagctgg aaccacgtcc atatgggcaa agattccgag
     9181 aacttcttct ccatcaccaa actcaaaatg tcctgcgtag ttatcgacat tcttagttgg
     9241 gtagccatca cggtctgcga tttcaaggaa tttttccaag gcttttactg gaccaggtcc
     9301 aaatggatgc tgggcatcag ccttgctatc atcacgttct gagttgattt ccaaaaggct
     9361 aaacaagtca gccaagaggt cttctttgcg tttttctact tctgctgtaa aatcaattgc
     9421 tatcattttt tcttcttcct atcttttttc gatgatttca tctactggca agcggtagct
     9481 tggttccaat ttttcgtctg tgtaacccac tgtgatcaag agttctgggc ggaaacggtc
     9541 ttcaatttcc aaaacctcat tgacttttga tttgtcaaat ccaagaataa tgttagaacc
     9601 aattccttgg tctgtcaatg caagaactaa gttcatggca accaaacctg cattgagagc
     9661 taggtagtcg ctgacttgtt gctcactgta acgggcaaac tcagctggca gatttttcat
     9721 aaaatattga agttgctctt cagaaaagtt attagcgcca ccaacacggg caatcttacg
     9781 agcacgtttg gctaagtccg tatctgtaaa caaggcaatg gttacaggcg ctgatgatac
     9841 ctgctcaaag tttgaaccat aagccaactt tgccagttca gcatttttct cacgaacaac
     9901 tacaaatttc caaggctggc tgttgtgggc gcttggcgcc aaggttgcaa tttcgatagc
     9961 cgtacgcaca tctttgggat caacaggctt atcagtgaaa tgcttggtcg catgacgttt
    10021 tttatttaat tcaagaaatt tcataatcga tttccttttc taattctact gcttccattc
    10081 taccataatt tgaaagagct tgcagggatt tttcatgatt aagtttttct atcacagaca
    10141 taaaagatat atattggttt atcaggaaag tttctgataa actagcaagt actttacatt
    10201 tgaatggaga cagtatgaaa aaatttagcc tattactagc tatcctacca tttttggttg
    10261 cctgtgggaa tcaagctaca cccaaagagt ccagctctca aaagacaatc gtcgttgcta
    10321 cagctggcga tgtgccaccg tttgactacg aagataaagg taatctgaca ggcttcgata
    10381 tcgaagttct aaaggcagta gatgaaaaac tcagcgacta cgagattcaa tttcaaagaa
    10441 ccgcctggga aagtatcttc ccaggacttg attctggtca ctatcaagct gcggccaata
    10501 acttgagtta cacaaaagag cgcgctgaaa aatacctcta ctcacttccg atttccaaca
    10561 atcccctcgt ccttgtcagc aacaagaaaa atcctttgac ttctcttgac cagatcgctg
    10621 gtaaaacaac acaagaggat accggaactt ctaacgctca attcatcaat aactggaatc
    10681 agaaacacac tgataatccc gctacaattg atttttctgg tgaggatatt ggtaaacgaa
    10741 tcctagacct tgctaacgga gagtttgatt tcctagtttt tgacaaggta tccgttcaaa
    10801 agattatcaa ggaccgtggt ttagacctct cagtcgttga tttaccttct acagatagcc
    10861 ccagcaacta tatcgttttc tcaagtgacc aaaaagagtt taaagagaaa tttgataaag
    10921 cgctcaaaga actctatcaa gacggaaccc ttgaaaaact cagcaatacc tatctaggtg
    10981 gttcttacct cccagatcaa tctcagttac aataacactc ttcgaaaatc tcttcaaacc
    11041 acgtcagctt tatctgcaac ctcaaagctg tgctttgagc aacctacggc tagcttccta
    11101 gtttgctctt tgattttcat tgagtataag atatactaaa agcgatggga tcagccaatc
    11161 gcttttttag tttgcattgg ttattttagg aaactcttac aaaaaatcaa aaaaattctt
    11221 cacatcctct acatacctat gcttttctat taagcttgct aatagttcca gattgtgcct
    11281 ctgatagtta tcttcacgac gtagttcttc atacatttcg ataaagggaa gccccttgga
    11341 tttggcaaat tctaactcag cctcgtaatc ataagcgact ttacgaaata ggatatttac
    11401 caattcccca tcttcaacct ctatcacggc atactgggca cggtgatttt ttaacgcctc
    11461 ccaattaaaa tagggcatgc caatcgaccc tggattgatg atttgttgcc cttgactacc
    11521 ataacgaagc aactgcttgt gaacatgacc ataaactgcc acgtccgttt ccgcatctag
    11581 cagttggtca aatttctctg tatcattctc aactagcaag tcaccaccat agtttttgtc
    11641 aggtaaatta tgagagatag aaaagcgcaa tccgtcaatt tctttctttt ccagcaaagg
    11701 caagcttcgt agccagacaa tcgttgcagg atccattcgc tccatcaaat actgtgtcat
    11761 acgcaagagc tgaacttcct gtgggtcttc taagccatat tgcccatcta aagcctcaag
    11821 gacacgatca tcccaattgc ctcgaacact tgctgtgata ggaaggtcct ttagcagggc
    11881 gactaagtca tttgcgcctg gaccaggaag aaaaatatct cccagaagcc agtattcact
    11941 gactccttga tttttagcat ctgcaatcac tgcttctagc gccgtcacat tgccatgaat
    12001 atctgataaa attgcgattt tatggtttat tgtggtttcc ttccgtttgg taatctactc
    12061 tttcttctgc tacttgaggc aaggcttctc cctgcgggtt caactttctt tgcacagcct
    12121 ctgcaacgac tctaggtacc ccaacttcga caatctcatc cacactggct tccttgattt
    12181 tggtcaaaga cttgaaatgc ttcataagat tttgcttgcg tttaggtccc agaccatcaa
    12241 tcccatccaa ttgagatgag aaagaatttt tggagcgcag ttggcggtgg aaggtgatgg
    12301 caaagcggtg cgcctcatct tggatgcgtt ggaggaggaa aaattcctga gaattgcgag
    12361 acaagtccac cacttccagc ggatctccaa agagcaattc atgggtttgg tgcttatcat
    12421 tcttttgcag acctgcaatt ggaatatcca agcccagttc ttcttggatg acttgcttag
    12481 caatattgac ttgaccttgc cccccatcaa tcacaatcaa atctggagga gtcaaagcct
    12541 cacgctgtac tcgaccatag cgtctgcgaa tgacctctcg catactggca tagtcgtctg
    12601 gcccgactac ggtcttgatt ttatacttac ggtaatcctt cttactaggc ttgccgttga
    12661 caaagaccac catagccgaa acagggctag ttcccatgat attagagtta tcgaaggact
    12721 cgatacgtac tggggtcggg atttggagca aacgccctag attttcaata gctccttgag
    12781 tcttttcgac agatttttct agcagattga acttctgctc tagactaaca cgagcatttt
    12841 ttatggctag attgaccagt tgttttttct ctccacgttg aggcttaaga atcttggaat
    12901 ccaccaaggc cttgacagcc tcttcgtcaa tatcctgcgg aatcagtacc tcattgggaa
    12961 ctagatgaga tttttcttga tagaattgtc ctacataggt caaaaaatcc tcatctggat
    13021 cattgaagta ggggaagaga ttgacatcgc gctcgataag cttaccctga cggacaaaga
    13081 aaacctgcac acacatccag cccttatcca catagtagcc aaagacatcg cgattttgca
    13141 aatctttcgc catgacccgt tgcttggttc gaagcgttcc aatagcctga atcaggtcac
    13201 ggtattccgc cgcacgttca aactccatac tttgtgctgc tactgccatt ttactcttga
    13261 gatcatcgat gattttgtca tcatgacctt tcagaaaatc agacacctcc tgagccatag
    13321 acttgaaata agcctcatcc ttcttacaga tggtgtgggc catacactgg ccgatatggt
    13381 aataaaaaca aaccttagag ggcgggttgg tacattttcg aaaagggaaa atcctatcta
    13441 gaagtcgctt gatttcattg gctgccccca catctggata aggtccaaaa taaagacctc
    13501 cgtccttttt gacctgacga gtgataatca agcgtggata gcgctcattg gtgattttga
    13561 tgaaaggata ggacttgtca tccttgagca tgatattgta cttgggcttg ttttccttga
    13621 tcaggttgat ttctaggaga agtgcctcaa tattagactc cgtaacaata aattcaaaat
    13681 ccacaatttc agacaccaga gcctctgtct tggtatcatg acttccacga aaataggacc
    13741 gtactcgatt acgcagattt ttagcctttc ctacatagat aatggtgcca tttttatcct
    13801 tatgaatgta gcaaccaggg ctggtcggca agagctctag ttttgattta atcaagttgt
    13861 tcatagttcc attatagcaa aaaagtaggg aaagatagta ccctactcac tagtctcata
    13921 tatttttcgg aggtttgcaa catcctcttc ctggatacca taaaaggaac ctgctggttg
    13981 catgacagac ttctcatctg tatggtccaa gccaatcgca tgacctaact catgttctgc
    14041 cgtatggaca aggcgttcat aggagtagcc atagtatgga ttggacaaat aataatgatt
    14101 caaccgcacc gttacggaca agaattgccc tgttaagaga ttagtttgac tttccgcctc
    14161 tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg ccttactaga
    14221 ctcagtcacg agttcaaagt taaaagcacc agtttgattc cagttctgga ttgcttctaa
    14281 ataagcctct tgaaagcgtg aatccatctg cggatccagg taaatacgag cagaggcctg
    14341 tgcccacctt ccttcagaat gctggtgact atctgtctgg cttaacttag gcagttgccc
    14401 tgttttctcc cattggtcaa tactttgttg accaattttt actgaccgtt ctgcttgctt
    14461 tagcgctcct tgaaaatccc cgttcagata ccagagaagt ccgaaagcaa gcacacataa
    14521 gagcacaact atccaaacca gacgccaaaa caaacgccac acaaaagaaa agaaagcccc
    14581 tatcaaacga aaaagccagc gcatgtctct ccacctttct agcaaataag aattatttta
    14641 ctaaaagaag ctaaaagaaa tctaaatact gactttttca tcttaacgtc ctactatttt
    14701 tttgagtaac tggatagctt tgtattttaa aggcgatgga tggtaacaga aagtacccgc
    14761 tttgcgtaca atatagccat taaaattctg tttaaaacgc aaaacaccat cacttccatc
    14821 aaaaatccct tgaatgccta ggaagttgta tttaggtatt ccacgtttta tgctttccaa
    14881 cataacatat ttttgaagca gtgcaggggc atagaactta ttaaactcag tgtaggaacc
    14941 actaaagaga taagtcgttt cctgaggcat ataaacaaat aaactcccag ctaaaacaat
    15001 atcttcttct ccatattttt caatcaagtc tcgcgcttct gcttttcgaa cttcaaacgt
    15061 ttcaaattga ctagaatatt ctctcagttg attttgtttt ttctcagaat gaggattttt
    15121 actcaaatca agtcgcaatt tgtccaagtt ttcttctagt ttattttgtt caccttgcaa
    15181 tttgctcata tagtccgaaa aatttaagct tgctatgaga aactccgctt gttctccaaa
    15241 agtatcataa aaatgctcat aatattctaa acttttatca ctatattctc tacgttcaga
    15301 ggtttctttt gttatattct taaaaatcga tagttcttca cgttttaact ttttcaaccg
    15361 aatgccaaag gtttcagcct ttttcaccaa gggtttaccc tttttgctaa aacttttaag
    15421 caaactcttt tcagttaatt cagttaaatc tttatagtat aaccaatctg gttctccacc
    15481 tgggtaacct gttgttaagc catcaaattg ataacctaaa tcagtcaaat cttgaataat
    15541 actttttttc tcagcatcta ttggattacc ttggctatca aaagtttgat aagtttcata
    15601 aggttttaca agcaactcta atacaccatt ttgcttggca tattctttta actctgcata
    15661 aaaaactgga agagcatctt gttgggtata aatcggcccc gaattgagtt ccatatgcag
    15721 accacccagc atgggcaagc tataaaccag agctgcaact tgaatttctc cttcttgttt
    15781 caaagcaaga taaacaattc gagcccctct tttttctagc aaatccccca tctggacaga
    15841 ttgcataaag gaacgagaag aaacctgatc agaataagtc tgaaactctt ctttcgtgag
    15901 tgttgttagt gccatatact tactttctat gtttttttct taatgtttta cggaaatcaa
    15961 gagcaagtct taacagagga tagagaggat gagtgggcat tgtaaattca cccaagtatt
    16021 cttcaatcgt tggattaaat ttttccttaa aatgataaag tccaccattg agagagtttt
    16081 caacaccacc taaattttgc cagaccatac ctcgctcaaa ggcatagcga gccgtttcat
    16141 accatgttaa aattggtgca ttgtaacgtt taaaatcatc atccatacca gcatatatat
    16201 tgacagaggt agtaccaaat tccaaactca aagtagccgc taaaggaact ctcgcttgac
    16261 ctacatctat atattcctgc aagaaggtca attcctctaa caaacgttct ttttccttct
    16321 tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa cgtctcttcc aaggatctat
    16381 ttttcgctaa ctgttcttct aattcttgcg aacgtttaga aacatccaag gtggccaagg
    16441 tgatataggc cttgtcctta aaattatcta acaatttttt ataataggct tcattcctca
    16501 aatgaatctc ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa tctaatagtt
    16561 ccagtccacc atattgaatc tcaagccctt tgtttcgtgc tgttcgaata gcctgttttg
    16621 ttgacttgga aagtttatct tcttcaaaat tttccttgta tattttcgcc tgaatacgag
    16681 gttgaatggt gtctcccatt tcctccgttt ttcctgacca ccttactccc atttgttgca
    16741 aactatcaat aatagccaga ttttcaggaa attctgtctt ttcctgattg attaaacttt
    16801 gagataggca aatacttggg tcaaaagtca caaaaaccgc tctcttactg cgagcatagg
    16861 acttaataga ctgaatggca aaattcaaga gttctttatc cccataatcc aatataggtc
    16921 ctcttgggat gtaaaacatt ttatagccta gcggaagagt tctaatcaaa atactagctg
    16981 tcgccagtaa tttttcttcc ctgtaaacac caaacttctc atgttgccaa ttagacttaa
    17041 cttcctccca agcactactt tgtaatacat tggctaattc atgttctttg acaaactgat
    17101 catattctaa tgtgggaatg ccaatttgat aacggtacat ttcctactct ctttcctcca
    17161 gtattttatt actattctac tactttcgtt tgaaaagtct agtgaaaaca tattttattt
    17221 tagttctact ccccctatgc tgaagttcaa actaagtcag tctctcttct aatttgaaat
    17281 caattggtag ggttgttaaa aaaacttcca attgtttttc ccagtagtac cactcgtgag
    17341 ttccagcact atggctatag gtcacatcaa aacctagttt tttgagattt ttcactgcga
    17401 gattattggc ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt ttggtctttt
    17461 tatccgattt tttagccaga ctttcaagag aatagggact agttgtccag tctctaatct
    17521 ctccaaaaac acctctccag taggctggac ttcccagatt ttgactttca ggagaaaagt
    17581 tttgaaagct gagggcacct gaaaaactag ctgcatgaga aaaacgattt gtcgtaagag
    17641 ccagtttgaa gcagccgtag cctcccatag aaagaccagc gataaagatc ttttcacgct
    17701 tgctagtcat attagggaag aagcgtttca gaacctgtgg caattcctct gctagagccg
    17761 tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc attgctggta ttgggcataa
    17821 caacgatgag attagttcct cgaagcaagc gttctacatt ggtccgctta agccaactat
    17881 tatgattgcc agacatcccg tgcaaaaggt acaagacggg aatatcttca cactctggtt
    17941 cttccactcg attggcatca gggtagagga cattcacccc ccactccata tccaatactt
    18001 gtgagtaata ctcgattttc attactgcca tgattttctc cttctatttt tctataagaa
    18061 aaagccgaaa ctcgactttc tctctgttta tttcaacgat tattttgctt ccatgactac
    18121 tggtaaaata gctggacgac gcttggtttg gtcaaagaga tacttggtca aattatctcg
    18181 aaccttccct ttaagatctg cccagtcaaa gtcatctcct tgaagataat cttctaccgt
    18241 ttggttaatc aattctgaac tttcacggag aatatcgcga ctcttcttga gataaacaaa
    18301 tccacgcgtg tgaacacgag ccctagccac aattttcttc tcacgacggt tgactgtaat
    18361 agccacgatg aaaattccat cctctgacaa gaccttacgg tcacgaagaa caacatttcc
    18421 aacatcacca atggcattcc catcaattaa gatatctcct gctgaaaccg atccagctgg
    18481 aacaaagtct ccattctcgt aagccatggt cgtccccttt ttaggaatga agatgcgttc
    18541 tggcaacatc ccaactgcca tggcagcctt agcgtgagca tccaactcac gatactcccc
    18601 ttggacaggg aagaggtact taggttgcaa aagattgatc atcagctgca aatcacgcac
    18661 atttccgtgc cctgatacat gtaaactttg ggtaatcaat ttgacaaccc cacctgcctg
    18721 ataaatcata ttttccacac gcgcaacaaa ggcttcttta gcaatagacg gagccgtagc
    18781 aatatagacc aggtccccat ccttgatttc tacataacga tggcgaccaa tcgacatctt
    18841 acgaagtcca ttgataggtt cacccatacg acctgtctca agaataatca actcatggtc
    18901 ttcaaagcga gacatatctt taggcttaat caagagaatt tcgttggcta aagacaactt
    18961 cttaagacga atcgctgtgc ggacgatatt ttcaatatca aatcctgtca agacgatacg
    19021 tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat tactggaaac
    19081 agctgcaacg atgatacgac cttcccagtc agcaatagtt tgggtaattt catccctaac
    19141 ttcactttca ctagccacct gaatattgct gtctgcattg gccgaatcac tgaggagagc
    19201 caggacgccg tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat aagattcact
    19261 agccgtttgg tcaaatttga agtcacctgt ataaacgatg cttccttccg atgtcttcaa
    19321 gacaattccc agactctctg gaacggagta agtcgtaggg aagaaggaaa ccactgtccc
    19381 accaaaatca atctccgtat tctcatcaat gacatggaaa tcattaaatt tcttaacggc
    19441 atcattacct ttgacaaaga gctttgccaa ctcaatggtc aactcagacc caaatacagg
    19501 aactttagcc tctgccaaga gataaggtag agcaccaatg gcatccgcat gcccgtgggt
    19561 caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt ttggaatcac
    19621 cacatcgacc cctaattgtt cattttcagg atattttaac cctacattca aaacaaaaat
    19681 ggactctcca atttcagcaa tgtacatatt ttttccattc tcacgcacac caccaagtgt
    19741 tgttaaactg atattactca tttttcctcc aaaatcttag tttatcttga ttatagggca
    19801 actctaccct cttattctaa aagttctgat actttcagcc gaatcttttc ctaccattat
    19861 accatttttt tgatgatttt caaaatgaag gtctgttttc aaaaaagagt tgatttccca
    19921 actctttcct aacttctact ctttttccat caaaaaatca taaatttctt gcaccgtacc
    19981 cagcgccatc atttcttggt ctttaacggt ttgtttgaga ttttggtaaa tttgactttc
    20041 tcctatctcc cgctttggcg cctctttatt gactgtcatc acaccatctt ttatcgtcac
    20101 aaagcctagt tcttcaaata cttgaatcat cttgaccagc aagatttgtt gaatattaag
    20161 atatgcagcc aaatctttca gcttgtagcg aatatcaaac tctgggaact ggtaaatagt
    20221 cttgtacaat ttggcaaact gatctctagt cccataacct gtcagataat aggccttgtc
    20281 aatatcattt ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg tcttcagctg
    20341 agtaatatcc tctggaatgt tttttacgac aacagcttca ctagccgcaa gatttggcag
    20401 ttctccagga aaatccaaga ctggaacacc ttctggcaag actgcatttt ttccacgaat
    20461 gttaaaaagt tgaacacctt ccactcgcgc atccaccatc atcaactgga gggcagtttg
    20521 gccattccat tggttgacag acaatttaac cgctaactct agattcttgg tttgagaaaa
    20581 ctctgtcgcc catctgcctt gaccaaaggc taccacttca aaactcgcct cacccttgga
    20641 aattttcagc tttagatggg cattacctgc ccccatagta cgagcacttt cgacctgaaa
    20701 attcttgata taaaaaatag gtttctgatt atccattcca aaaggagcta aacgttcaaa
    20761 acttttgacc gtttccaagc taagtgcctc caaatccaac tcttcatcta ggtttaactt
    20821 attcttgcca ccagcatctg cacctttttc acgaacataa tcttccaaaa cctgagataa
    20881 atctgagagt tgctcaactt ccagcgtcat acccgctgca cctgcatgac ctccaaaggc
    20941 gatgaagagg tctcgatggg gatccagagc ttcaaaaata tcgaccgctt ccacactacg
    21001 agcactgccc ttggcacgac cgtcttctat attaagaaca atgactgtct gtcccaattc
    21061 ttccaataaa cgaccagtca cgattcctag aaccccagga ttccagcctt ccttggccaa
    21121 gacctgaacc ttcttctcag gatccaccat ggtcttggct tcttcataga tagactgaac
    21181 gatttccttg cgctcttcgt ttttctggtg aatcataagg gcaatctcat gcgcttcctc
    21241 atcatcaaat ccagtcaaca aatcaatggc aggattggga tcatccaagc gacccaaggc
    21301 attcaaacga ggagcaatct ggaaaccaac cgtttcttct gttacttcgt tggcagcaat
    21361 cccagccatg tccagcattt cttgcagacc aatgcgctgg gtatgaccca acatttccag
    21421 accatattga actaagatac gattttcatc cgtcagactc accatatctg caatagttcc
    21481 aatagcgacc aaatcaagca attccacttg cacttcttct aacagggcac aagccaactt
    21541 gaaagcaact ccacaaccag ccaaatattt aaaaggataa tccgcatctg gatgttcagg
    21601 atggacaata gcataagcat ctggcagggt ttcaggcatg gaatgatggt ctgtcacaat
    21661 gacatctact cccatagact gagccaatgc aatagcctca tgaccagcaa ccccattgtc
    21721 caccgtcaca atcaaggaaa ttccttcttg ctcgataaag tatttataaa cactagcatt
    21781 agggccatag ccatcggtaa aacgatttgg caggtaaact cggcactcag caccaagttg
    21841 ttccaaactt tccttcacaa tagaagccga agtcatgcca tccgcatcat agtctccata
    21901 aacgagaata ttttcccctt cttcaatagc ctgacgaatc cgctccactg ccttgtccat
    21961 atcatggagc agataagcat catgtaagta ctccaaggaa ggttctaaaa acttcttcag
    22021 actttcttgg tcctgaatcc ctctctcaaa caataaccga gccacctcag gacccagtcc
    22081 agccttcttg gctatctttg taaaatccgc atcttctacc tgcagggcaa actgccattc
    22141 ataagtaggt gttatcaaaa agacatccac tctttctaag aattctattg cttcattata
    22201 acatgattta gacgttttct ctatccagat tgctttttta taacatttta tagtatattg
    22261 aaactagaat agtacacctc tacttctaaa atattgttag aaatcgattt gactgtcccg
    22321 atcgattttt cctgttctta tttcactata gtgaattttt tcagatatga tttgacaaga
    22381 acattctttt attgcagaat cgtgttataa aatctaacat aaaggagttc gctcatggct
    22441 ttagtagaat ttaaaaacgt cgaaaaatat tacggagact accacgcact ccgcaacatc
    22501 aatctccgtt ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg ctctgggaag
    22561 tccactctta tccgtacgat caatggttta gaggctgttg acaaaggaag tctcctagtc
    22621 aatgggcacc aagttgctgg tgccagccag aaagatttgg tacctcttcg caaggaagtc
    22681 ggcatggttt ttcaacattt taacctttat ccacacaaaa cggtgttaga aaacgtgaca
    22741 ctttcgccca ttaaagttct aggaattgat aaaaaagaag ctgaaaaaac cgcccaaaaa
    22801 tatctggaat ttgtaaatat atgggacaag aaagattcct atcccgccat gctatctggt
    22861 ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta tgcatccgga actcctcctc
    22921 tttgatgaac caacatctgc tcttgatcct gagactatcg gagatgttct agcagttatg
    22981 cagaaactgg cgcatgatgg gatgaacatg atcatcgtta cccacgaaat gggctttgct
    23041 cgagaggttg cggaccgcat tatctttatg gccgacggag aagttttagt agatacgaca
    23101 gatgtcgata acttttttga caatccaagc aaacctcgtg cccaacaatt cctcagcaaa
    23161 attatcaacc acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa aaaattcttt
    23221 ttatcagcat tattgattag ccttttcggc cttgctgctg ccaaaccagt ccaggctgat
    23281 actagtatcg cagacattca aaaaagaggc gaactggttg tcggtgtcaa acaagacgtt
    23341 cccaattttg gttacaaaga tcccaagacc ggtacttatt ctggtatcga aaccgacttg
    23401 gccaagatgg tagctgatga actcaaggtc aagattcgct atgtgccggt tacagcacaa
    23461 acccgcggcc cccttctaga caatgaacag gtcgatatgg atatcgcgac ctttaccatc
    23521 acggacgaac gcaaaaaact ctacaacttt accagtccct actacacaga cgcttctgga
    23581 tttttggtca ataaatctgc caaaatcaaa aagattgagg acctaaacgg caaaaccatc
    23641 ggagtcgccc aaggctccat cacccaacgc ctgattactg aactgggcaa aaagaaaggt
    23701 ctaaccttta aatttgtcga acttggttcc tacccagaat tgattacttc cctgcacgct
    23761 catcgtatcg atgccttttc cgttgaccgc tctattctat ctggctacac taataaacgg
    23821 acagcactac tagatgatag tttcaagcca tctgactacg gtattgttac caagaaatca
    23881 aatacagagc tcaacgacta tcttgataac ttggttacta aatggagcaa ggatggtagt
    23941 ttgcagaaac tttatgaccg ttacaagctc aaaccatcta gtcataccgc agattaagga
    24001 ggatacccta tgacagattt atcatcttgg acagcctatt ttcaggattt tgaacaattt
    24061 ttcaatggtt tcctctttac tcttgcccta gcgattggat cctttatcct cgccatggtc
    24121 ttaggaatct tctttggtgc catgtcaacc agtaaacgtc caattttacg cattttagct
    24181 cgcatctttg ttgaatttta ccaaaatact cctctcttgg tgcagtttgt tattgttttt
    24241 tatggcctac ctcttatcag tgaccatatc atcatgattc caatttattg gacagccgtt
    24301 ctctgcgtgg gactctatca cggcgcttat atcgctgagg ttattcgttc agggattcag
    24361 tctattccta gtggtcagat ggaggccgcc ttgtcgcaag gttttaccta tatcagtgcc
    24421 atgcgcttga ttaccttgcc tcaggccttc cgcatcattc tccctccatt gaccaaccaa
    24481 attgttaacc tcatcaagaa cacatctact gtagctatca tctctggagt agacttgatg
    24541 tttgtgacta agtcttggtc ggctctcaac ggaaactata tcccagcctt tttaggtgct
    24601 gctcttctct actttgccct atgcttccct gttgcccagt ttggtcgcaa gatggagcaa
    24661 gccaataaaa aagcctattc actttaggag gttactatgg aatctatttt agaaatttta
    24721 accccagata acctagtctt tatctttaaa ggatttggct tgaccctcta tatttctctg
    24781 attgccatca tcctctctac tatcatcggt accgtgcttg ccgtcatgcg aaatggaaaa
    24841 aatcctatct tacgcattat ttccagtatt tatatcgagt ttgtgcacaa cgttcccaac
    24901 cttctctgga tttttactat ctttttggtg ttcaaaatga agtccacacc agcaggtatt
    24961 acagccttta ctctctttac atcagcagcc ttggctgaga ttattcgagg cggtctcaat
    25021 gccgtagaca agggacaata caaagcagga atgtcacaag gcttcacctc agcccaaatc
    25081 ctctactaca tcattctccc acaagccagc cgcaaaatgc taccagccat catttctcag
    25141 tttgttaccg tgattaagga taccagtctc ctctactctg ttatcgccct acaagaactc
    25201 tttggagcca gccaaattct catgggccgt tatttcgaac cagagcaggt cttcagtctt
    25261 tacatcctga ttgccctcat ctacttcagc tttaacctag caatttctag cctgtctcat
    25321 atgctagcca aacgttggca acaagctgca gaataatact cttcgaaaat ctcttcaaac
    25381 cacgtcagct tcaccttgcc gtatatatgt tactgacttc gtcagttcta tccacaacct
    25441 caaaacggtg ttttgagcag cctgcggcta gcttcctagt ttgctctttg attttcattg
    25501 agtataaaca gccactctcc agttcaattg gagagttttt tgatgagagt agatatttat
    25561 agacctcaat ttgacaccat acattttcta tgataaaatg taacaaattc atttacaaca
    25621 aatcgaaatc taaatgaaat ggaattttct atgaaatcag tcaaaggact actctttatc
    25681 atagctagtt ttatcttgac tcttttgact tggatgaaca cttctcccca attcatgatt
    25741 ccaggactag ctttaacaag cctatctctg acttttatcc tagccactcg tctcccacta
    25801 ctagaaagct ggtttcacgg tttggagaag gtctacaccg tccacaaatt cacagccttt
    25861 ctctccatca tcctactaat ctttcataac tttagtatgg gcggtttgtg gggctctcgc
    25921 ttagctgctc agtttggcaa tcttgccatc tatatctttg ccagcatcat ccttgtcgcc
    25981 tatttaggca aatacatcca atacgaagct tggcgatgga ttcaccgctt ggtttaccta
    26041 gcctatattt taggactctt tcacatctac atgataatgg gcaatcgtct ccttacattt
    26101 aatcttctaa gttttcttgt tggtagctat gcccttttag gcttactagc tggtttttat
    26161 atcatttttc tatatcaaaa gatttccttc ccctatctag ggaaaattac ccatctcaaa
    26221 cgcttaaatc acgatactag agaaattcaa atccatcttt gcagaccttt caactatcaa
    26281 tcaggacaat ttgcctttct aaagattttc caagaaggct ttgaaagtgc tccgcatccc
    26341 ttttctatct caggaggtca tggtcaaact ctttacttta ctgttaaaaa ttcaggcgac
    26401 cataccaata atatctatga taatcttcaa gccggcagca aagtaaccct agacagagct
    26461 tacggacaca tgatcataga agaaggacga gaaaatcagg tttggattgc tggaggtatt
    26521 gggatcaccc ccttcatctc ttacatccgt gaacatccta ttttagataa acaggttcac
    26581 ttctactata gcttccgtgg agatgaaaat gcagtctacc tagatttact ccgtaactat
    26641 gctcagaaaa atcctaattt tgaactccat ctaatcgaca gtacgaaaga cggctatctt
    26701 aattttgaac aaaaagaagt gcccgaacat gcaaccgtct atatgtgtgg tcctatttct
    26761 atgatgaagg cacttgccaa acagattaag aaacaaaatc caaaaacaga gcttatttac
    26821 gaaggattca agttcaaata agtaatcata ctctcctgga atttcccagg agagtttttt
    26881 atagccaaat gaaataagac aggaacgatg gaattttggc attcaaatca attgataaga
    26941 atgttttata gtggagtgaa ataggatacg aacaaattga ttaggaaaat caaatgaatt
    27001 tatagaaatc ttttagcagt tatgttatcc tattctagtt tcaaaacgct atagaagcag
    27061 cattgtgcta gtctagattc agtttactat actaaaacga gtagcttgaa atcaaaaaac
    27121 ccaccctcac aggcaggttt tatctgtatt attcagctag attatgcttt accttctgaa
    27181 ccgaatacgt cgatacgttc ttcaaccgat gcttggatag cttttacacc gtcagccaag
    27241 aatttacgtg ggtcgaagag ttttttctta tcgtattctg cttcgtttgc ttcgtagtca
    27301 cgagcaaatt tacgagttgc gttagcgaat gcgatttggc attctgtgtt aacgttaact
    27361 ttggcaacac caagtttgat agctgcttgg atttgctcat caggaatacc tgatccaccg
    27421 tgcaatacga ttgggaatcc tggaagagct tctgtcaatt tttgcaagtg gtcaaggtca
    27481 agaccttccc agtttactgg gtaagggccg tggatgttac cgataccagc tgccaagaag
    27541 tcgataccag tttcaaccat tgctttagcg tcttcgattg gagccaattc acctttaccg
    27601 atgattccgt cttcttcacc accgatagta ccaacttcag cttctactga gataccttta
    27661 gcgtgtgctt tttcaacaac ttctttagcc aatttaaggt tttcttcaac tggaaggtgt
    27721 gaaccgtcaa acatgattga agtataacca acttcgatac actcaagtgc atcttcgtag
    27781 tgaccgtggt caaggtggat agctactggt acagtgatac ccattgattc aacaaggtta
    27841 gcgatcaagt tgcgagcaac tttgtaacca cccatgtatt tagcagcacc cattgaagtt
    27901 tggatcaaaa ctggagcttt tttagcttct gctgcgcgca agatagcttg agtccactca
    27961 aggttgtttg tgttaaatcc accaactgca taaccgttgt cacgggctgc ttggacaaat
    28021 ttttctgctg aaacgattgc cattttatca ggcctcctgt atatttttat gggtcatccc
    28081 atttacattg ttcattttat cactttttgc caaaaaaatc tagtttttcc cgcagtttcg
    28141 attgattttc ttctaactcc atctatgtaa accctttctc tccctagtct tggacgactt
    28201 ttggaaaatc tataaagaag gttaaacgat tctcctccat ctcgaaacga taagctaatt
    28261 tttcatgttc taatagactc ttaaccacaa agagccccat accagacccc ttgaccttgc
    28321 gactagcatt gtcagaaaaa gactgggcta gtttttcttg ttcctctgag ctacagctat
    28381 tttcgataaa aagttctcct tctctttctc caattcgaac taagccacct ggaacagagt
    28441 gcttaatggc attgctgatg agattagaaa gaatcaactt cataactgat gggtttagat
    28501 aagcctgctg atgggtcaaa ctattgtcta tctggagctc tctttccttg gctagcaagg
    28561 cataatcttt gaccagattt tgcgtcatct ggaggaggtc aattgtttcc ctatcatctc
    28621 gcaattcctg cacagaagag agggaaagta tctgcagaac atggtgattg agttcatcca
    28681 caatccccaa ggcaactccc agatactggt ctctatcctt ataacgaccg atattctctc
    28741 tcatattttc gattaggatt ttcaaactag ccagcggtgt tttcaattca tgagaagctc
    28801 ctcgtaggaa ttcgaccttc atcttctcca gctggagaat ggcttcattc ttttcatgca
    28861 agtccgcaat aacagtcaag agatgctggt agaggctatt gatttgttcc ttgagattac
    28921 ctatctcatc cttagaatcc acgcgcaatc gcacttggga atccaggtcc atcatccgac
    28981 gggtcacccg cttgatttcc aaaatcggtg caacaatagt ccgagcgtag atgtaggcca
    29041 ccaagaggga aatcagaaag gaggccagca aggtataggg aagaaactgg agactgattt
    29101 gctctgcttc cttttgtaaa tccatggaag ctagaaactg gagaatcata gtaccaccgt
    29161 cttgcgtttt cacctcgcgc tcctcaataa agagagaggt tgtctggcgg tctgtgtcca
    29221 gaggaagact gtccttgact tctaacttat cctcggtcat ctcacctttg acggtcccct
    29281 tgatatcact agtctgggaa tacaagtcta acacttgctc gatactctgc ctatctttcc
    29341 cttctaggga ctgggcaatg gctgttgcct tttgaccaat ggtttcctga cgatgactca
    29401 gataagtcga aggaaaaaga aaataaatag ctaaatgaag gcagataacc agaacactaa
    29461 atatcgagaa ggtatatata aatatctttg taaataaacc tgttcgtttc attttcgctc
    29521 caatttataa ccaacattgc gcacagtgag gatacaatcc aagtctagct ttttccgcaa
    29581 ttccttgata taaacatcaa taacacggtc aaagggaacc tcatctgtcg ctttccagac
    29641 ggcatcgata atctgagacc gagtcaaggc ccggccttca tttttcacta gatagtccag
    29701 aatttccaac tctttggcat tgataggcac ttcttgacct gcgaggcttg cactgtagct
    29761 ttcaaagtcc accttggtat ccttgtaaga aaagattcgt cctgtatcgt agtagcgctt
    29821 gaaaatcgcg tccaccctca cttttaaaag ggagagggag aaaggttttt ccagatagcc
    29881 atctgccaaa gaggcaaagg cactcatctt gtattcctca tcctgaaaag ctgtcaacat
    29941 caagacagga acctgactgg ttttacgaat ctcagctagg acttctaagc cgttgagctt
    30001 gggcatctgg atatccagta aaaccagggc cacctcatag ctagaaaatt gctccagagc
    30061 ttcctgaccg tccgctgcct caatagtttc atagccacaa tccgtcaaat aatcactgac
    30121 cccctcacgg atcatctctt catcttctac aattaaaatt ttcatacttt aactgctctc
    30181 tattttttat ttttcttaga ataaatacct actctatttt ctattatagt ctcttgctgg
    30241 ccttttgtct gtaagcaact gaccactaga taaaacgttg tgaaatcctt tctcataaat
    30301 tccataactt tagtatatta tatttaagca ctaaagtaca aagaaagcaa ctgaaagcaa
    30361 tgattttcac cactgctttc ggatttattt tgaattgtta aatagccatt cctatccact
    30421 attcttgaat agaaacacaa gatgcaatct ttattccaga ctcatttttt caaatttatt
    30481 caccatccag caagagctct tttggttgtt ttctaaggag attgcttgaa gcaagcgcca
    30541 taacgagaac cactagaacc aaggcaagga caaaaatgat gataaagtct gatgtctgaa
    30601 tggaaatgtc taggctcgac aaggtcttgc taaagccatc tacttctgca ccaccaccaa
    30661 ggttagaggc ttgagccgcc ttactagcct gtttggcaac acctgaagtc acattggcaa
    30721 ggacagtgtt tccaattgca cgggcagtgt aattagctag gaagtaagca gaaactagag
    30781 cagggatagc aatcaagata gattcggtga tgaattgacc caagatactt gcctgcttga
    30841 ggccgataga gaggagaatt cccacttcct tgcgacgggc gttgatccaa aggctgagca
    30901 agagggcaag gaggagaact gagaagctca agctacccca gaagaggagg ttggccatct
    30961 tgtacatacc agagatagat tgctcaagag ctgggtagtt agaggagctc ttgacgagtg
    31021 tgtagctctt ccagttgata ccactgatgc cattcaactc tttcataaca tcatccaagt
    31081 tcttgtctgc tgttacaaag aaggttgcgt ccccataaat ggctgtgtct tctgtgtatc
    31141 cataaagttt tgcagcagtg tgaatgtctg taatagctgt gttttcgtaa agttcttgtg
    31201 agtaggttac tgctgactta ttatgaccat caaagagtcc cttgattgtc acttcaactg
    31261 tttccttggc tcctttttca ttatctgcat cgtagatatt agagtccagt ttaaccttgt
    31321 cccctacttt ccagccgtgt ttggctgcca agtccttgtg caagaggatt ttatccttgt
    31381 cgtcgttggt taagtgctct ccttcgacta gtttataaga accagagaca aacttgtctt
    31441 ctttagagga gtcattgaca cctgtaatca tcaagctact tccaaaacgc ttggcacgat
    31501 cagcagtgag attcttcttg gtttctggcg tttcaatcag gtcatatcca gtcaaatctc
    31561 cgatagcgtt gatacgtttg acataagact caatggcctt gttttcggtg atttttttga
    31621 tgtcttcacc cttgatattc ccagcaccac gaggcgttcc ttggttgacg cgacgattga
    31681 tttgcatgga gaagctattg gtgatatttt taaaggtctc ctgagaagcc ttggcagtag
    31741 ctcccttgat tgacaagccg accaaactca agctcgccat gaggagaata atcaggaaga
    31801 tgacaatcga tttgaaaaac ttccttgtaa cataggcaaa tgcgttgtgt aacatagatt
    31861 ccctttctag attttgtttt aatcattcta ttaaaataag ctcaaattat ttactagtat
    31921 tgcgcgtttc agtcagtttc ttatccttta attcaagtgt aatatctgac gcttgtgcca
    31981 cttctttact gtgagttacg acaatcacac atttacctgt tttctgggca agtgatttga
    32041 gtagttcgac aatatctcca gcagttttag gatccagatt tcctgttggc tcatcagcta
    32101 gaataactgg agcttctgag accaaactgc gagcaatggc aacacgttgc tgttgaccac
    32161 ctgataactg gagaacattc cgcttgatct gactttcatc caaaccaagc tcaagaagtg
    32221 tatccttgct tgcctttttg ttgaccaatt ggatattttc cagcggagaa agataatcta
    32281 tcaagttata attttgaaag accagggaaa tatggtgcat gcgatggtaa gaatagccct
    32341 tcttacgaat atcctctcct tgaaaaagga tagaaccttc aacaggacta tctagaccag
    32401 caagtaggga caagagtgtg gattttcctg ctcctgactc cccaataata ctgtaaaatt
    32461 ttccgggttc aaaattataa tcgatctgat ataggactgc ttcagcagta ttcttataac
    32521 ggtaggtaac atcttgtaat tgtaataaag tcatgatttc tccttcttaa ctaatagatg
    32581 ataaaatttc tttcggtgat tttctaaata agaataggaa acaaagggct acagataagc
    32641 aactaagcag aactagaaaa acataggatt ctgcaaaaga taagatacta gttgataaac
    32701 tgcttgcttt ggctagtgta tcttgtaagc ttgcctgatc tccacttgct agtagagttt
    32761 ggagtaggta agttgtgatt ccgtttcctg caacaaatgc tggaagcaaa gctccaagag
    32821 ataccaaaac tacctctaaa cagaattgta ggaagatcga gctcttgcct tttccaagtg
    32881 caagtaaaat ccccacttca tagacccgtt ctctcaacca gagagacaaa accagaatta
    32941 aggctccagc tcctgctatc aacatcccat aaaggaagat ggtcaggaag gtttggaaag
    33001 ttgcaactga gtctttgatt tgttcaaaag ccttgttttc cttttcgact tggtagcctt
    33061 gattttccaa ggccaagttt tctacctgct tcatgagtcc gtccatttcc ttaggatttt
    33121 ctacatagaa gcgtgctgca ctgacttgag cttcactatt gcccaaaagg gtttggctac
    33181 tttcatagtc tgtaaagact tgattttcac tgaagtcaga agacaagcct gtgaatttct
    33241 cttgtttttt accagaaaag atgccaataa tctcaaactc tactgtttgt ccttttccag
    33301 attcagactg accagcatcc aagccaatct tgtcatgaag tgaaagaccg ttcttcttag
    33361 ccaattcttc gtggataagg attttcttgg aatccccttt ttgaaggtgt cgcccttctt
    33421 ttagattgaa agccgaactg gtaaaggtta catccttgga tgaatcctca agagccgtta
    33481 agctaaccaa gttattgtct gcagctgata aatcatcacg ctccacgctc tgctcgccag
    33541 tcactgcttc cttgtctttt agttttgcga ccgtctcaag ttcaggagag acattttcca
    33601 gccccttaat cttgcttaca gatgctaggt ctgacaactt gaatgtctga ccattctcta
    33661 tcttcttaat agaaaaagat gtattgagtg atttataaag attgctttct actgttttgt
    33721 tggacttcat cagagtcaaa caggctgaaa ttccggccaa taagaccaat aaaatcagaa
    33781 ataaaataaa acttctcagt cgctttctgc tgacataagc ccaagatctt tggattggat
    33841 tcatttgtca cctccatatt tgtaagacta ttataaaacc caaatatgaa atgtttatga
    33901 aatacgaaaa aaaatatcga gtaggggata atctctagcc cctctcacac caccgtacgt
    33961 gccgttcggc atacggcggt tcaactaact tttaacgcat gtcgttcaag gtaataatcc
    34021 aaacacgaaa cctgttcacg tttttcaagg actggttttg atatagcacg tttaagtacc
    34081 gacttctgag ctactatagt agattgaaac tagaatagta catctcttct tctaaaacat
    34141 tgttagaaat cgatttggct gccctgatcg attcgtccta ctcttatttc attttactat
    34201 aattgatagt ggtcgctcca gccagatacc ttatctgcta tccatttagg aacccctaac
    34261 ttaagcaatc cccataatcg tctcgatttc ttcttccatt gcttccagat aatcactcgt
    34321 aggcgagtac gcaagcgctc atctatgcta gtgactatac ttttcatatt tataattcat
    34381 tcctttcgtt tcactcaagg cacaacacag aatgaaaaag tgttgtgctc tttattttgt
    34441 tttataataa tagtgagaaa gcctatcact actacaaatc acggggaggt gaataagtga
    34501 gtggtacagc cactacctcg catattttgt cacatcattt aacggtacat aataagttgt
    34561 accatctgaa taagttgcta caatatcatt tgcatgctct ccttcacctt tagcaaaggt
    34621 tggagctcct gctggataat ttttatttgc ctctttcaat ttttcaataa tggcattttt
    34681 ttctgtatct tttatattat caggattttt cactaagatt ttgtctggat atgtcggttt
    34741 agcagaaaca atttttactg ttatttcttt tttattcgaa gcacttgtcc agtttccagc
    34801 attatcttta gcatttaatt ttacagtaat tcctgaacta ggaacttcag tagcaggttg
    34861 attatcaaca ttattcaact ttaatttcaa aagagctgtt gcatcagacg ttttatcaat
    34921 cgttgtatat aatgatgaat tgttattata accagtttct tcatatttag ctgtttgtga
    34981 gctacttgaa acagaactga aattatgccc actacctccc tgattatctt caatgcttac
    35041 gtctaaatga acttccccac tattatttgg cttagcaaca actgttatag taaaataaca
    35101 taaaatttgc ataaatagat tagggaaatc aaagcagctt ctaggaatgt tttagcagtc
    35161 acagtgtact ttcccagcat caagccacta taactctgca cataaaaatg gagaagatgg
    35221 caatcctctt ctccaaatat taacttcttt acaaaccaac tatagttgac aaagaaccta
    35281 aaatcaattg ataacacaag gtcaggtcgg tcaactcttt caactgaagc cctgtcaact
    35341 cttcccattt atcaatcttg tattggagag aattgcggtg cagatagagt tgctgggctg
    35401 ttttagtgag aacagcacta ttttcccaaa gagagagaat gatttcctga atctgatctt
    35461 gatccaaaat catctggtgt agacattctt taattggctt caagtccacg agtctttctc
    35521 ccatactcca aagatagagc tgagaaaaag tatgaacacc ttggtgaccc tgacgccacc
    35581 atgtcttgaa caaatcccgc tcagctttga ttaagtctga tagggcttga tgtcctgtct
    35641 gagaccaaac ctgacccaac atgatagaaa gacgaagtcc aaagtcatac tcaaccgctt
    35701 caatcgtatc acttaaaata tctcttacag aagtgtattt gtcttgttga agcacgaaaa
    35761 cataatcctg aactccgacc tgtagcactg tctgacaatt cggaaaaaga gtccgcatca
    35821 tatctagcca agaagccaga ttttcctgct gaaaataaga aagatggcaa taaaccaact
    35881 gaatcttttt aaaaacttgc ggtgcctgtc ccttgccttc aaccagatag gaataccaag
    35941 ggtttagcga acgagcctgc tcctgctggg tcaaaagggc aaccaactgc ttttcacgct
    36001 cgctgagccc agcttcctcc agcaaaatcc actgctgaga agctaaaggg agcgtgagat
    36061 agccctcttt ctctactggt tggtctgaaa tccgagcctc aggaaaccag tcttgtagtt
    36121 ctttttccct catgttctag ccctccactt tttggatgca ccatgaaacc aaactctcaa
    36181 gacgttccag attctcagtc atatggagat agcccataac cgcttcaaat cccgtggaca
    36241 tacgataagt cacgacatct gcatttttag cctttgtgtg gctattggta ttgcggccac
    36301 gtttgtagat ttcttcttct ttttccgtta ggacctgctc ctccaacatg agagcaatca
    36361 ggcgagcctg agccttggct gacacatact tggttgcttc ttgatggagt ttattgggtt
    36421 tggtcatacc tttgaggatg aggtgacggc gaatatacat agaatacacc gcatccccct
    36481 caaaggctag cgcaatcccg ttaatgagat tgacatcaat cacgtgtcca cctcactcca
    36541 tccttggtat caaggagctt aattccttga gtaaccaatt ggtcacggat ttggtctgct
    36601 gtcgcaaagt cacgattggc acgcgcctct tggcgttttt gaatcaagtc ttcaatctct
    36661 gcatccaaaa cttcctcaac aaagacaatt ccaaaaattt ctaacatatc tgcaagagct
    36721 tgcttgacac ttgcatcata gttccctgag ttgatccatt tggccatttc aaagacaact
    36781 gtgataccgt tggcagcatt aaaatcttca tccatagctg ctacaaactt atctttaaag
    36841 ttttgtaact cttgggcatc cacgtttcct gtaaatggtt gttcgtaagt attcttcaga
    36901 tacttgagat tggtctcggc atcgcgaact gccttttccg tgaagttgat aggcttacgg
    36961 tagtgctggg tcgcaaagaa gaaacgaagt acttgcccat caagagtttt aagggcatcg
    37021 tgtaccgtaa tgaagttacc caaggactta gacattttga cattgtcgat attgacaaag
    37081 ccattgtgca tccagtagtt agcaaaagcc ttgcctgttt tagcttcaga ttgggcaatt
    37141 tcattggtgt ggtgtggaaa ctctaggtca gctccaccac cgtggatatc aatggtatca
    37201 cctaaaatct ctgtcgacat gactgaacac tcaatatgcc aacccggacg tccaggtccc
    37261 caaggactat cccaagaaat ctcacctggt ttggaagatt tccatagagc aaagtctaca
    37321 ggattttcct tacgagccgt ttcttcatcg gtacgacctg aagcacctag ctccaaatct
    37381 tccaaggttt tattagccaa tttagcatag ttgtgggatt tttctacacg gaaatagaca
    37441 tccccttgac tctcataggc aaagcctttc tcgatcaagt cttccacaaa acggatgatg
    37501 tctgccataa actccactac acgcggatgg cgagtcgcag gtttcacgcc caaggccgtc
    37561 acatcctcac gaaaggcagc gatgtactta tccgcaacct cctgaggcgt gatgccttct
    37621 tccctggcac ggttgataat cttatcatcc acatctgtaa aattggaaat ataggcaacc
    37681 ttatacccac ggtactcaaa atagcgacga atcgtatcaa aagctaccgt cgaacgggcg
    37741 tttcccacgt ggatatagtt gtacaccgtt ggcccacaaa catacatctt gatcttgccg
    37801 tcctcaatcg ggacaaattc tcgcaaatca cgagacatgg tgtcatagat tttaatcata
    37861 aatcataatc aggaaagcta aaatccaaga actgttagtt tcatcactaa actaagagct
    37921 caagtaaatt tcagtccgaa tgtctctaca cttcggaatc ccttgctcct ttctcattca
    37981 gataaaccac ctgtgtctgt ttgacaaagc caattttttc atacaaacgt ttggcaccta
    38041 cattgctatc ttccactgca atctgaaatt ccttatcatt ttgctcaatt agttggttga
    38101 caagggattt tgctaagtag cttccatagc ctttcccacg ttcaggttct gatattgcta
    38161 aaccgtagaa gtaattcgta tcgctcgata aatcaaccgt gcaagtccca ataacctgac
    38221 cagcttttaa taaaatatat agtcggcttt ctggatcttt cagagcttca gcgacatatc
    38281 tatccacaac ttctctcgat tcatgttcct ctgaaaatgc ctgaaatttt aattgactaa
    38341 tttgatcctg atacgaacta tctgctaaca aaatttcaag atgggaaaca tttgctaacg
    38401 gataaggtct tctatcctta cctaaccaag tttctgtctc ttcatcctcg attagtcccc
    38461 agttactggc aaagtcagga tgattctcta aaaaaatacg ttctgtctga aaagtgactg
    38521 accgaatagg gaaagaagct gtttctctct caaaactagt aaacaatgca cgcgcaatcc
    38581 cctgacggcg atgacctgga tgaaccagta tcgtcacttc tacatcttgg tcatctgcat
    38641 agacagttaa taaaccaaca agtttgcctt tttcataata aaggaaaaag gcgggcatgt
    38701 ttgggtcaaa attaagcatg ttagagagat agggatcgcg ataggtaccg tcatagtttt
    38761 ggcaacagtt aattactttt ttcgcctcag atagctcctc ttggcttaac ttgtttcttg
    38821 cttgaatcat ataggtatcc tctacaaacc agacgatctg tgactggcat ctttagcctg
    38881 ctcgagttta ttgacataat actctcgttt ttcttcgact tcgtgaataa caggctcatc
    38941 tttcttacca tgaagacgga caatcttggc cggaataccg acaaccgtca catcactagg
    39001 tacatctgct acgacaactg ctgcagcacc gaccttggca ttttcaccaa tttccacagg
    39061 tccgataact tgggcatggg ctgatatgag ggctcccttt cgtacagtcg gatggcgttt
    39121 gccacagtct ttccctgttc ccccaagagt cactccgtga tagagaagaa cgcctttttc
    39181 aacaatcgct gtctctccaa tcaccagacc agaaccatgg tcaataaaga cacctgaatc
    39241 aatctgggct cctggatgaa tctcaatctg agtccaaaag cgccaaaact gactgtgcat
    39301 acgagctaag agtttgaagc tgtgcttcca gagaaaatgc gagagacggt gggccgccaa
    39361 ggccttgaca cctggataag tcagcaaaac ctccaaagtg gtgcgggccg ctggatcatt
    39421 ttcttttacg atatcaatgg tttcgcgcca ccaccccata catttctcct tttcttattc
    39481 tgaatctttt ggtgtttctg taaattcttt cttaggtttg tgatccttgt gatgacgtgg
    39541 gcggtgaggg cgctcagact tttcaccttt ttcatcatgc tcaggttttg gcggacgagg
    39601 tagaagagcc ttcatagagg catcgatacg gcctttttca tcaatcttga taaccttaac
    39661 atcaacttca tccccgattt ctaccaaatc ctctacacga ttggtacgag tccaagccat
    39721 ctcagagata tgaacaaggg catctgtctt atcaaagagg ttaacaaagg caccaaattt
    39781 ctcgatacga acgactttag cacggtaaac ttcatccact ttggcttcac gaaccaaacc
    39841 agcaataatt tctttggcac ggttaatagc atcttggtca ctagagtaga tagacacatt
    39901 tccttcttcg tctatatcaa tcttaacacc tgtttcagcg ataatcttgt cgatggtttc
    39961 tccaccctta ccgatgacaa tcttaatctt gtccacatca atcttgatcg tatcaatttt
    40021 cggagcagtt ggagccaatt ctggacgaac ttctggaatg gttgcttcaa tgacatcaag
    40081 gatttcaaaa cgcgctttct tggcttgagc aagagcctcc gtcaagattt ctgcagtaat
    40141 cccttgaatc ttgatatcca tttgaagggc tgtaatccca tcacgagtac ctgcaacctt
    40201 gaagtccata tctccaaagt gatcttccaa accttggata tctgtcaata ctgtgtagtt
    40261 atttccatct gagataagtc ccatagcaat accagctact ggcgccttga ttggcacacc
    40321 accagccata agggcaagag ttcccgcaca gatagaagct tgagatgaag aaccgtttga
    40381 ttccaaaact tctgctacta gacggatagc gtatgggaat tcttccaagc ttggcaagac
    40441 ttgagcaaga gcacgctcac caagggcacc gtgaccgatt tcacgacgac ctggcgcacc
    40501 gtaacgacct gtttccccta cagaatattg agggaagtta tagtggtgca taaagcgttt
    40561 cttgtactct ggatccaaac catcaatgat ttgagtttct cccatcggag ccaaggtcaa
    40621 gactgaaaga gcttgagttt gcccacgagt aaagagacct gaaccatgta cacgaggaag
    40681 gaagtcaaca accgcatcca aaggacggat ttcatcgacc ttacgaccat caggacgcac
    40741 cttgtcttct gtaattaaac gtcgcacttc tgcgtgttcc atttgttcca agatttcagc
    40801 cacatcacgc ataatacggt caaattcttc gtggttcgca tatttttctt cgtaaacggc
    40861 agtcacttgg tctttcactg cttgagttgc agcttcacgg gccaatttct cttctacttg
    40921 aactgccttt tggaggtcac tgttgtaggc tgcaatgatt tcagcttgca attcagcatc
    40981 cacgtgaagc aattccactt ctgctttttc tttaccgaca gcagcaacga tttcttcttg
    41041 gaaggcaatc aattctttga cagcttcgtg ccctttaaga agcgcttcca acatgatttc
    41101 ttctgacaat tctttggcac cagactctac catgttgata gcgtgcttgg ttccagctac
    41161 tgtcaattca agaagagatt gctctgcttg ttcttgactt gggttgatga tgatttggcc
    41221 atctacatat cccacttgta ccccagcaat tggtccgtca aatggaatat ctgaaataga
    41281 cagtgccaaa gatgaaccaa acatagcagc cattggtgca gatgcatttt catcataaga
    41341 aagcactgta ttgatgactt ggacttcatt acggaaacct tccgcaaaca taggacgaat
    41401 cggacggtca atcaaacgcg ctgtcaaggt cgcatctgtt gaaggacgtc cttcacgttt
    41461 cataaagcca ccaggaaact tcccagccgc atacattttt tcttcgtagt tgacttggag
    41521 tgggaagaaa tccccagttg ccattttctt agacataacg gcagcagtca agacagttga
    41581 ctcaccgtaa cgtacgacaa cagatccatt tgcttgctta gcaacctgac cagtctctac
    41641 aattaactca cgacccgcaa aagtcgtttg aaacacttgt tttgccattt taatcccctt
    41701 tggattgatg aaattatacg ccttgcctac aaagatcaag ataccaagga cgtcaaaagc
    41761 aaagtaaaaa taggaaactg acgaagtctt cgatgaagac aagacagttt atctttttta
    41821 cacagctttt cggccgtgtt caattactca agataccaag ccgtcaagca actcaaagga
    41881 aaataggaaa tcgaacgacg gagcgactgc tcctagggag atttatcttt ttccacagag
    41941 ttgtaggcaa gttcagtttt caagatacat cattagaaag gtttaatact aaagtatcta
    42001 aagctttcac gctaatcgct atcgggcgat tagctaaatg ctttactaac tctctcgtca
    42061 aataacatcg atttgactca ctcgtgtcgt taaatcttac agtttaaatg cattgtatta
    42121 tttaatacct tcatctttgt atcaagtacg tacagaattt attttatcat atttttctta
    42181 aaaagtgagg tctttaccat taaaaaggaa ccattcccct cacctgagaa gaatggtttg
    42241 cttttattat cctagagact ggtgattaaa caaggcatgg gttgcttgat ggatgtattt
    42301 tgctgtatca gcattattca tcgtatagag atgcacaccg gcaacatcct gagttaccaa
    42361 gtccacgatt tggtccactg cataggcaag tcctgctgct ctgagcgact cagggtcatg
    42421 ctcatacttg tctaagatgg ctttaaattt gcgtggaaga tggatattct cacaagtctt
    42481 caagagtcgg agagcctgat ttcgattcag aattggcata attcctgcat gaatgggaac
    42541 atcaatccca gccaagatgc acttgtcctg aaaatcatag aagcgctcat tgtcaaagaa
    42601 gagctgagtt acgaggctcg aacagcctgc atccactttc ttcttaagat tttgaatatc
    42661 tgaaatctga tttggcgaat ctggatgccc ttctggatag caagctccaa taatatcaaa
    42721 gtgaggggct cgttccttga taaactcaat caagtcggtt gcatagcgga aatccttttg
    42781 tggttccacg tctggaataa tatccccacg aagagccaag attttctgca ccccaacttt
    42841 gtccaagtca gcaatagttt cagcaacctt gtccttagtt agataaatag ctggcaagtg
    42901 ggcaatggtc ggaatcgcca aatcattttg gataaagtca gccaaacgaa ccgtcgtttc
    42961 cttgatatta aatttattat tgctggcagt tacactgata aaatggggag ccaactcctg
    43021 catatcctgc aaggctgaaa taatgttacc attacccacg gctgggtttg gagggaacac
    43081 ttcaaatgag agtgacggtg tttggcgtga catatgtaat aaccttttct agttgatttc
    43141 tttttgaaca accactgtat ggagagaaat ccaatcttac aatttctcac gcgcagcttt
    43201 agctgcttca acaaggcgga tcaagctttc ttttgtttct gggataccac gtgttttcaa
    43261 accacagtca gggttgatcc aaactttctt gcttggcact ttagcaagga tggcttcgat
    43321 tgtgttgtcg atttcgcctt catttggtac acgaggtgag tggatatcgt aaaccccagg
    43381 tcccacttct gtttggaagt ttttcgcttt gagttcgtcc aagatttcaa ggtttgaacg
    43441 gctagcttca aaggaaataa cgtctgcatc catgttatcg atagctggga tgatatctgt
    43501 aaattctgag taacacatgt gagtgtggat ttgtgtgtct ggcgctactg ttgagtgtac
    43561 caagcggaag gcaggaattg cccagtcaag gtagtcttcg taccagtcgc tacgacggag
    43621 tggcaatttt tcacgaagag cagcctcatc gatttggatg atcttcacac cagcaacttc
    43681 aaggtcaagt acttcatcct tgatagcaag ggcgatttga agagttgaat ccttgataga
    43741 gatgtcttca cgtgggaatg accagttaag aatggtaaca ggtccagtca acataccttt
    43801 aacaggtttg tttgtacgac tttgtgcata gctagaccat ttaacagtga tagggttaag
    43861 acgagtgaca tcaccccaga tgattggtgg tttcacccca cgcataccgt atgactgtac
    43921 ccaaccattt ttagagaaga ggtaacctga caagttttga ccgaagtact caaccatgtc
    43981 attacgctca aattcaccgt gaacaaggac atcaaagtca atatcttctt gccacttgat
    44041 ccattcgtca atcgtttcag caaggaaagc gtcgtactct ttttgagaca attcaccttt
    44101 acggtaagcc aaacgtttgg cacgaacttc ttttgtttga gggaatgaac caatcgttgt
    44161 tgttggaaga gctggaagtt tgaaagcttc ttcttggata gcttcacgtt ctgcaaaggc
    44221 tggcaaacga gtgtagtctg cgtctgtcaa gccagcgata cgcgcacgaa gttcagcatt
    44281 ttcaccaaca cgctcagtcg caaagagttc tttgttggct gcaagagctt ctgaaccttg
    44341 accattgcgg atagcatcca agtcacggat ttcatccaat ttttcaactg caaaggcaaa
    44401 gtggttcaag agtgctggtt caaattcttc attagcagtt gtaaatggca catgaagaag
    44461 tgagcaagag cttgtcaaaa cgatgttttc agctgggatt tgctcaagaa cagccaagct
    44521 cttttcgtag ttgttgcgcc agatgttttt accattgaca atacctacat agagagtctt
    44581 gtcagctggg aagccacctt taacgagttc aagagttttc ttaccttcaa caaagtcaag
    44641 accgatagca tctactggca agtttacaag gtcagcgtat acgtcacgaa catcaccgaa
    44701 ataagtttga agcaagactt caagaccttt tttgtcagcc aagagtttgt tgtaaaggtt
    44761 caagaagaga gctttttctt cagctgtcaa gtcttttaca agagccgctt catccaattg
    44821 gatgcgagtc gcaccaagtt cagccaattt agcaaaaact tcttggtaag cagccactaa
    44881 gctatctacg aagtcgtctg ctttcacgcc ttcttcaaag tctgacaatt gaaggaaagt
    44941 gaatggacct acaagaacag gacgagtgtt caatccaagt tcttttgctt cttggaactc
    45001 atcgaaaatc ttgtgaccag ccaattttac ttgagtgtct ttttcaaatt taggaacgat
    45061 gtagtggtag ttagtgttga accatttctt cattggaagg gcgcgaacgt cccctttttc
    45121 tccctggtaa ccacgtccca aagcgaagta gcgctcaagg tcagacaagt ccaagttttg
    45181 aacggatgca ggcaccacgt tgaaaaggaa agccgcatct aggaagttat catagtgaga
    45241 aaagtcattt gatggaattt cagtgatgcc tttttctttg acaatgttcc agtgtttagc
    45301 acgcaagtct tttgctgctg ctaaaagttc ttcttctgag atttcttttc taaagtattt
    45361 ttcagttgta aattttaatt cacggaattc gcccaaacga gggaaaccga tgattgtagt
    45421 tgacatgatg tgtcctccaa aatttgttgt tgaaactatc ttaacagaaa agaaatcatc
    45481 tgtataattg taaaaaatta ggctttgata tagtttgaaa ctatacctct gttttagaca
    45541 aaagaaaaag acttgagaca catgcctcaa atccctttta taacttgttt ttagctgtat
    45601 tttagttaga atgctcaaaa gcgttattag taattcttat aagtgactat ggcttgttat
    45661 tagaaaagac tataactgat tctagtcaac ttttcccctg ttcaagtcgg acgactgcta
    45721 gtatctttcc tagactagct aggactttta agactgtgtc caactgtgga ctagtcttac
    45781 ctgtctccat cctagctata acaggctgac tcactccact gagttcctct agctttttct
    45841 gactgattcc ttgcttattt ctggcttcaa tcaactcgct catgatagct actcgcatat
    45901 cactttcaag gatttcctcc ttgctaaaga gctcagatgg acatccttcc aattactccc
    45961 aatagcacta ttcttcatca cttaaccctc tttcttttac gtctatgtat ttttaaaaaa
    46021 atgagcgaat tatgattcga tagattgacc agcgggttta aagttggtgc tagcctattt
    46081 cttaagcgat tttccttttc taggataaag cagatcctgc ttgcttaacc ccaattttcc
    46141 acgatgaatc caatagtaaa tggttgaaat tcccacgtta acccctttag ccataaccat
    46201 catttcaggc gaaaattttt ggttatgtat agtggaatct tttcctttag ttccttggtc
    46261 aagcttgatt tcttgaccga gcgcttgcga ttgttttcat aacactgttg agcgtagtcg
    46321 gcagaataaa cctctttgaa gcgccctttt ccaagacatt ttcggactgt cccacgcttg
    46381 atttcagtgt ggatagtttg aggagctttt ccaagtagag aggcaacttc tctatttgat
    46441 tttccttctt ttttccatct ttcgattaag cgacggctat cgattgtcaa atgtttacct
    46501 tttgtagtat aattgtcttg catctctgtg ccttttaatc atttcaatct taaattggac
    46561 tttttttact tgggttgtac ttaatctatg aggaagacaa gaaaaagaat atcaatcaag
    46621 taaagtcaca aagtcacatt agctccgagc aaccattgca aattgaggta ctcacacaat
    46681 gattaaaaca tttctctctg ccctttcggt cattctcttt gttatcccta tcataactta
    46741 ttcttttttt ccatcttcta atcttaatat ttggctatct accagaccta tcttggcaca
    46801 gatttatgcc ttccccttag ctactgcaac tatggcttct attttaagtt tcgtattttt
    46861 ttccctatct ttttacaata aaaataaaca aatacggttt tactctggca ttttgctctt
    46921 actatcgctc atattactat tattcggaac agataaaacc ctttcttctg catcaaataa
    46981 gactaaaacc ttaaaattag taacttggaa cgtcgctaat caaatagaag cacaacatat
    47041 tgagcgaatt tttagccatt ttgatgccga tatggctata ttccctgaac tagctaccaa
    47101 gatcagaggt gagcaagaaa accagagaat caaactattg tttcatcaag ttggactttc
    47161 tatggccaac tatgatattt tcacttctcc acctaccaat agtggaatag ctcctgtgac
    47221 tgtgattgtc aagaaaagtt atggtttcta tacagaagct aaaacttttc atacaacacg
    47281 gttcgggaca attgtattac attcgagaaa acaaaatata ccagatatca ttgccttgca
    47341 tactgctcct cctctgccag gtttaatgga aatctggaag caagacttaa acatcattca
    47401 taatcaattg gcttcaaaat atccaaaggc tattattgca ggtgatttta atgcaactat
    47461 gcgtcatgga gcacttgcaa aaataagctc tcatagggac gcattgaatg cacttccacc
    47521 ctttaaaaga ggaacttgga atagccaaag tccaaaactt tttaatgcaa caatagatca
    47581 tattttattg cctaaaaacc actactatgt taaagattta gacattgtaa gttttcaaaa
    47641 ctctgatcat agatgtattt ttacagaaat cacattttaa ttattttata taaaatcacc
    47701 cctctagtgt tcataaacta gaggggtgat ttgtatcata ctatcgttta acgcacttct
    47761 gcattgactt tttcttcgag agaagcttgg attttttcca tatagcgtgc gacttcttcg
    47821 tccgttaagc tatcttctgg attttggaag gtcaagctat aagccatgga cttcatacca
    47881 agtcccaatt tctcacctga gaagacgtca aagagtttga tatctgtcaa acgtttcacg
    47941 ccggcagctt ggatagcatc tacaacttct tgatgagtca cttctgcctt gaggagaagg
    48001 gcaacgtcac ggctgactgc cgggaatttg gtgatttcta caaatggagc cgctggctga
    48061 agcgcagctt cgatagctga aaggttaagc tcagctacat acgtttctgg aatatcataa
    48121 gccttagcag tgactggatg cacttggcca aggaaaccaa gaacttggtc accgagtgaa
    48181 atcacggctg tacgacctgg atgaaggcta gcgatttcag atgttgctgt ataggttact
    48241 tggagtccca aacgagcaaa tagggcttca aggattccct tagcatagaa gaaatcaact
    48301 ggaactgctg ctgtttggaa atctttttca gcaaccaagc ctgtcaaggc aaaggcaaag
    48361 ctgttgatct catttggaag ttcttctttt ggattacctg tttgttcaaa gacttttcca
    48421 atctcgtaaa gggccaagtt tttattctta cgagccacgt tgtaggcaac ggtatcaagg
    48481 atacctgaaa tcatattttg acggaggact gaacgatcca cagtcattgg ccacatgagt
    48541 tccgtaaggt tacttggttg agccgtaaac tcaactgctt tttcaggagt tgttagagta
    48601 taggtgatga tttctgtcaa acctgctcct tcagcaatag tacgaacttg acggcggagt
    48661 ttttgtgtgg ctgtcaattc acctgctgta ccatcgtctt ttggtagact agttggcaag
    48721 cggtcataac catagatacg agcaatttct tcaaagaggt cagcttcgat tgtgatatcc
    48781 caacgacgac gtgggactct gactgtaaag ctgtctgcat ttccagaaag accaaagcca
    48841 agacgacgga agacgtcttc tacatcagca taagacagct cagttccgag gacacggtta
    48901 acatcagcaa gggttgaaga aacttctaca tctgaagtat caagctcacc cgctgaaacg
    48961 atgcccttac gcaccgtcgc acctgcaagt tccgcaatca ggctagctgc cgcatcaagg
    49021 gcttcattaa ctgttgccac attaattcct ttttcaaagc gagaagatga ctcagaacga
    49081 aggttcaggc gaccacttgt cttacggata gatttgccat tgaaaacagc agcttcaagg
    49141 acaacacgac tagatttttc agagatttct gttgcttgac cacccatgac acctgcaagg
    49201 gctactggct tgtctgcgac agtgatgact aggtcattca cgtccaagtc acgttcttca
    49261 ccgtccaagg tcaccaattt ttcaccagca cgcgcttcac gcacacggat gtcagtccct
    49321 tcaaatgtgt ccaagtcaaa agcatgcata ggttgaccaa agtagagcag gatgtagttt
    49381 gtcacgtcta caacgttatt gatgggacgg atgccttcgt tcatgagaag gttttgcaac
    49441 cattgtggac ttggtgcgat agtcacattg tccaagatac gagctgcata gtaaggcgcc
    49501 ttgtctgtcc caatgctgac agaaagggca tctgccgcag attcattagt ttctgttaga
    49561 gtaaattctt taaagttgac tgccttgtca tagatggctg ccacttcgtg agccactcca
    49621 cacatagaaa gggcatctgc acggtttggt gtgatggaaa gttcgatgat ttcatcatcc
    49681 aagtctaggt aagaaaagac ttcctcacct ggcacggcat tttctggcaa gatttggatg
    49741 ccatctgcga attccttagg cacaactgag tcagaaattc ccaattcacc aagtgaacag
    49801 atcattccaa gtgactccaa accacggatt tttccttttt tgattttgta gttatcagcg
    49861 atacgagctc ctggaagagc caccatgacc ttgatcccag cacgcacatt tggggcacca
    49921 caaacgatct gacgctcttc ttcttcgcca acgttaacct gacaaacatg gaggtgagtc
    49981 tctggcacat cttcgcaaga caagacctca ccgacgacaa tttttgagag accagcagct
    50041 ggtgattcga caccctctac ctcgatccct gtagttgaca ttttttcagc caactcttgt
    50101 gatggcacat caatgtccac caattctttt aaccatttat aagatacaag cataatttag
    50161 ttctccagaa tgaccattgc cacactggtt cttttccttt cctatcattt caatagaaga
    50221 atcctcttct taccttaatt tctttctcag taaccaatcc gtatctactt tttgaccaac
    50281 cataaaatga tgttggctaa atttttcaaa accatatcga ttataaaacg cttgagcttt
    50341 tgtattatgc tcccaaacac ctagccaagc ccaagaaaaa ctattttttg tagcaagttc
    50401 aagtgcgaat tcaaacagtt gcttacctag tccaaatcct tggaattttt gtagcacata
    50461 gaggcgttga atttcaaaag cgtcctctaa ttctctctca gtttgagcac ttccccagtt
    50521 gactttgaga aaaccagcta tctcctcctc atgcataatg aaataggttt cagagtcagg
    50581 atttcccaac tcagttgaca aagtttttag actataagcc tcttcaaagt attcctgtaa
    50641 ctgctcttcc gtattatcat acgcaaaggt ttcacgaaag gtttgtttgg caattttagc
    50701 caacacctca acatctgcca tttctacttt tctaatcatt atttaaactg ttctgagaag
    50761 cggacatctc cttggtagaa tccacggata tcgttgattc cataacggag catagctaca
    50821 cgctcttgtc caagaccaaa ggcaaagcca gagtatacag tcgcatcgat accactcatt
    50881 tcaaggacac gtgggtgaac cataccggcc cccataattt cgatccaacc tgttttctta
    50941 catacattac agccttctcc accacacttg aagcaagaaa catccacctc aacagatggc
    51001 tctgtgaatg ggaagtaaga tggacgcaaa cgaatttgac gctcttcacc aaacattttt
    51061 tggacaatca actgaagcgt tccttgaaga tcagccatag agatattttt cccaactacc
    51121 aagccttcga tttggtggaa ttggtgactg tgggtcgcat cgtccgtatc gcgacggaag
    51181 acacgccctg gcgagatcat cttcaaagga cctttagaaa aatcatgggc atccatagca
    51241 cgcgcctgaa ctggagacgt gtgggtacgg agcaagattt cttcagtgat atagaaagta
    51301 tcctgcatat cacgagctgg gtggtctttt ggaaggttca tacgttcaaa gttatagtag
    51361 tcttgctcca cttcaaaacc atccacgact tgataaccca taccgatgaa gatatcttcg
    51421 atttcttcac tggtttgtgt caaaacgtga cggtgaccag tcgcaactgg acgacctgga
    51481 agcgtcacat cgatactctc gctagccagt tgagccgcga ctttcttttc ttccaagagc
    51541 ttagctgttt cttcaaaagc agctgtcaag acatcacgag cttcattgac gtgtttcccg
    51601 atgattggac gcatctcagc agaaacatct ttcatccctt tgaggatttc agtgagcgaa
    51661 ccctttttac caaggacaga gacacgcaaa tcttgcatct ctttttcatt tccagcagta
    51721 atctgcttca agctagccag cgtttcttcg cgaagcgctt ttaattgttc ttcaatagtt
    51781 gacatatttc ctccatcagt ctctcgtaga taaaaagaaa accacatgcc aaaaactcca
    51841 ctcggagcgt tgacacgcgg taccatccgt tttcatctga caagtcagac cttcatttct
    51901 aaatccatgc gcaagtgaat tcacccagct ttcatataga gagcttgcag tcacggctct
    51961 cctccctgat atacttccct tgggctacta gtctttcaga ttcctattca attactactt
    52021 agtttatcag atttttacca ttcttgcaag acctatctta cttctgcttg ttagcttatt
    52081 cttatctaac tttatagcgg attgaaataa gatgagaaca aatcgattgg gaaagtaaaa
    52141 ttaatttcta taaacgtttt agcaattatt tcgtactatt ttagattcag tctactatat
    52201 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
    52261 attaatcccc ctatgaaata aagaggttta gaatttgatg tcttccaaac ctctttattt
    52321 catattcaat gagatgttgc cttaaccgtg ataatatcta atcatcaata aacaaactat
    52381 ttgaataagg attctccatt tgattcaatc actcctttat accaagtaaa ggacattttc
    52441 ttatatcgat tgaatgtgcc atttccatca tcatttcgat caacataaat gagaccgtac
    52501 ctcttagaaa gctgtgcagt ggacatagaa acgcagtcaa tacatcccca agacgtatag
    52561 cccataattt ccacaccatc ttgtagagct tcagctactt gcaataaatg ttctttcata
    52621 tactgaattc tataatcatc ttggactgtt aagttattaa attcatcttt tattagttga
    52681 tctttagcac ctaatccgtt ttccactata aataatggaa tttgataacg gtcataatat
    52741 ctatttaaaa ttatacgtag tccaattgga tcaatttgcc atccccactc tgaagactct
    52801 aaataaggat ttactaaacc accaataata ttcccttctc ctgaattata ctgtgttgga
    52861 agagcagatt gagtcacact catgtaatag ctaaaggata aaaaatctac ggtataattt
    52921 tttaataact ctgcatcttc agctgcaaac tctatgttaa tgtcatgttc cttaaaatat
    52981 ctttttgcat aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga
    53041 ttctcatact catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc
    53101 atagctaata ccatacaccc caccttaaac tctgaattaa tctcacgagc aatttttgta
    53161 accaaactcg aggcgactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga
    53221 ttctccttag gtatatctat tcctccacta gtaaacggta attccaaaac agagtttact
    53281 tcgttaaatg taagccaata tttaacttta tctttatacc tttttaaaac tgttcgagca
    53341 aatttttcat aaaaatgaat cattctccta tcaatccatc catgatattt tcttgctaaa
    53401 tataatggag tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg agcatgtagt
    53461 tcatcaaata attcatcata atatttcaaa ccagcttcgt taggttcttc cttatctcct
    53521 tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa
    53581 aacaaggata tatcttcctt atatttatga taaaaatcaa tacctaacaa ctttaagtta
    53641 tcttctgtag gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact
    53701 gataatccct taccatcttc attatatgct ccctctactt gattagctgc aacagctcca
    53761 ccccaaagaa aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt
    53821 aattccttag aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca
    53881 ttggtattcg ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc
    53941 aagtccattt caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta
    54001 ataaaacctt gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca
    54061 ccctcatcac tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca
    54121 tcaaatggtg cataaacctt accttcactt gggataatcg ctactccgtc tccaattagt
    54181 ttatctgaaa atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga
    54241 gaaaatatca tttttttatt tgaaactcca acttcaactt ctaaattgct agaactctct
    54301 tcttcatcga ttccaaatat ataagctaat acaaaggtaa taacaaccga aatgaccgcc
    54361 acaattaaag catttacaat atttgatggc acatcagaat aaataaattg aggcaacgct
    54421 atcaaagatg ggacagcaaa tagatatgct ttaacactag taagacctgc aaataatccc
    54481 gctaatccac caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca
    54541 tataatgcag gttcggtaat ccctgcaagt aaggctgaga aacctgctgc aaaagcaatt
    54601 tgttttgtat tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct
    54661 aagtttgacc ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc
    54721 aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca
    54781 ccaagaatag ctaatgtaag ccatccagct acaccataca tttgcccaac tagatttgat
    54841 aatccttcac caacaattac tccaataggt ccgactacaa ctaaggcaat acagcttgat
    54901 actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa cagctggtgt taatttagca
    54961 atcatttttt caatatattt catcaaccaa accataataa gaattggaac gactgacgaa
    55021 ccataactag ctggtgtcac aggtacacca aataaactaa gaggattccc tgattgcacc
    55081 atttgaacaa aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt
    55141 acttttaatt tttgtgatgc agaataagct aataacagcg gtaagaaata atatggagca
    55201 tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt
    55261 ggtaaaataa ttaccaagac tttcagcata cctcccccta acattgctgg aatgattgga
    55321 gtcatggaac cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga
    55381 acaactgaat cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca
    55441 tcattaccaa gtataatttg atattgtcca ttctttttca taatacctat tacacctggt
    55501 atcttcttca catcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt
    55561 gttacacaat gggtaactct attgacattt ttttcacctc caattacatc gaggattttt
    55621 tgtaccgtat ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta
    55681 agcgacgaat atgagccatc aaataaacta attcactaga agtcagcaaa taattgtact
    55741 cagtttgtat aaacattgcc acctgttcac cacattcata ttctctagga tatttatttt
    55801 tcattaatgc taacaagtct tcatcatcat cgtcacaata agttgtattt tcaaccaagc
    55861 gatgggcaaa taattttata tgagttatga atctataata atcaatagaa tcttggttaa
    55921 actcagtaca atagaaatct tgaatgattt tctcaattcc cataattatt tcagtgattt
    55981 tatacgactc ttgaaaatta ttttctaaat tagcattaac aaaatgtagc gctatgaatg
    56041 cagcttcgtc aattggaagt tcaataccta actctttttt tattatttgt aaagcccttt
    56101 tcccaagctc aaattcttct ttataatatt tcgagatttc ccagcgtagg ggattcgaaa
    56161 taataactcc ttctttataa cgttctatac tcgaagaaat atgatccgtt agatttatat
    56221 agataatctc atcaaaatta ttacctaatg ttattttacc tagattaatt attttttcgg
    56281 tgatgtacac caactccaaa ggaacgttaa taaacatctc tgtaaaacgg gtcatgttat
    56341 ctctattttt gagaaaaaaa cttttctcaa tatcaattgg atttacttta tctccaattt
    56401 ttcttccaaa agctattccc cttccaaaaa gaagaatatc gatatctttt ttactttgcg
    56461 caattacggc attgtggttt agtattcgtt ttatgatcat aaaatttccc ttttaaaata
    56521 aaaggaacct acttaaaaaa catcaagaaa cttcttctga tgtgattaaa taggttcctg
    56581 ctcacttgta ttagtgataa catcctttta tttcaatttt taatggtgac atgaagctta
    56641 aataattaat aactctgtaa ccgtttttat tttatgatat ttcaatctat ttgtcaagta
    56701 cttataaaaa tttttttatt ttgtgtgatt cgaatgtgat aatggcaaca gtctcactaa
    56761 agaaatgaaa atcatacata gaaattttta aaaattttct ctatcgtaaa cctgccacta
    56821 gttcagaaac tatactagct gattccaaac gtaatatggt catctcatct acctccccta
    56881 ataatggcat tgcaccatac caaacaatag tcttattcac caaaagaata ggcgttacta
    56941 tttttgattg agtaaaagac actttaattt tctggctctt caactgtgaa ctacacccca
    57001 aaagttagac agaaaaaatc taacttttgg ggtgttttat tatgaaacta acttatgatg
    57061 ataaagttca gatctatgaa cttagaaaac aaggatatag cttagagaag ctttcaaata
    57121 aatttgggat aaacaattct aatcttaggt acatgattaa attgattgat cgttacggaa
    57181 tagagttcgt caaaaaagga aaaaatcgtt actattctcc tgatttaaaa caagaaatga
    57241 ttaataaagt ctgacatgaa ggctggacta aagatagagt ttctcttgaa tactgcctcc
    57301 caagtcgtac gatacttctt aactggctag cacaatacag gaaaaacggg tatactattg
    57361 ttgagaaaac aagagagaga gtacctgaga gcggagaatg ccatcctaaa aaagtta
//
LOCUS       DAVHSI010000012        52326 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.012, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000012 DAVHSI010000000
VERSION     DAVHSI010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.012"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..2413
                     /locus_tag="VVR21_000793"
     CDS             <1..2413
                     /locus_tag="VVR21_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU6054706.1"
                     /translation="TIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVLATRAYERYK
                     EQPNVLKRAYMLKEILENMFIYIEEESMIAGNQASSNKDAPIFPEYTLEFVLNELDLF
                     EKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETGFFGMEGKMN
                     SGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSIFIVIDAIKV
                     YAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSVWFIQCILQI
                     ESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITINKVRSQSHTF
                     SSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRYHAGLDARFM
                     NECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAVPGKWGYRCT
                     GMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDKTLRYLTRMS
                     VIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQVGIANLSDSL
                     AAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDDDYADKLVTA
                     AYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDGRNAGTPLAE
                     GCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLIALLRT
                     FFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDIIGR
                     TEHTL"
     gene            2432..3100
                     /locus_tag="VVR21_000794"
     CDS             2432..3100
                     /locus_tag="VVR21_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU6054707.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            3118..4206
                     /locus_tag="VVR21_000795"
     CDS             3118..4206
                     /locus_tag="VVR21_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU6054708.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            4661..7162
                     /locus_tag="VVR21_000796"
     CDS             4661..7162
                     /locus_tag="VVR21_000796"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU6054709.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            7356..8051
                     /locus_tag="VVR21_000797"
     CDS             7356..8051
                     /locus_tag="VVR21_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054710.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            8063..8479
                     /locus_tag="VVR21_000798"
     CDS             8063..8479
                     /locus_tag="VVR21_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054711.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(9106..9198)
                     /locus_tag="VVR21_000799"
     CDS             complement(9106..9198)
                     /locus_tag="VVR21_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU6054712.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            9359..10330
                     /gene="ruvB"
                     /locus_tag="VVR21_000800"
     CDS             9359..10330
                     /gene="ruvB"
                     /locus_tag="VVR21_000800"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU6054713.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            10311..10883
                     /locus_tag="VVR21_000801"
     CDS             10311..10883
                     /locus_tag="VVR21_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU6054714.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            11114..11872
                     /locus_tag="VVR21_000802"
     CDS             11114..11872
                     /locus_tag="VVR21_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU6054715.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            11881..12684
                     /locus_tag="VVR21_000803"
     CDS             11881..12684
                     /locus_tag="VVR21_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU6054716.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            12706..13965
                     /gene="rseP"
                     /locus_tag="VVR21_000804"
     CDS             12706..13965
                     /gene="rseP"
                     /locus_tag="VVR21_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU6054717.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            13978..15831
                     /locus_tag="VVR21_000805"
     CDS             13978..15831
                     /locus_tag="VVR21_000805"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU6054718.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVIAEEEVIRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            15930..17309
                     /gene="bglA"
                     /locus_tag="VVR21_000806"
     CDS             15930..17309
                     /gene="bglA"
                     /locus_tag="VVR21_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU6054719.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            17502..19310
                     /gene="glmS"
                     /locus_tag="VVR21_000807"
     CDS             17502..19310
                     /gene="glmS"
                     /locus_tag="VVR21_000807"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU6054720.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            19429..20478
                     /locus_tag="VVR21_000808"
     CDS             19429..20478
                     /locus_tag="VVR21_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU6054721.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(20578..24420)
                     /gene="spuA"
                     /locus_tag="VVR21_000809"
     CDS             complement(20578..24420)
                     /gene="spuA"
                     /locus_tag="VVR21_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU6054722.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPAASPA
                     DSAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTIRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            24837..25250
                     /gene="rpsL"
                     /locus_tag="VVR21_000810"
     CDS             24837..25250
                     /gene="rpsL"
                     /locus_tag="VVR21_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU6054723.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            25270..25740
                     /gene="rpsG"
                     /locus_tag="VVR21_000811"
     CDS             25270..25740
                     /gene="rpsG"
                     /locus_tag="VVR21_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU6054724.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            26165..28246
                     /gene="fusA"
                     /locus_tag="VVR21_000812"
     CDS             26165..28246
                     /gene="fusA"
                     /locus_tag="VVR21_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU6054725.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            28350..32741
                     /locus_tag="VVR21_000813"
     CDS             28350..32741
                     /locus_tag="VVR21_000813"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU6054726.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEAIYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIVDLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            32843..33106
                     /locus_tag="VVR21_000814"
     CDS             32843..33106
                     /locus_tag="VVR21_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU6054727.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            33150..33377
                     /locus_tag="VVR21_000815"
     CDS             33150..33377
                     /locus_tag="VVR21_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin, RelE/StbE family"
                     /protein_id="HEU6054728.1"
                     /translation="MKRGLKAELLEEVLNFLVQEKEHPARYRDHSLTASKHFQGVREC
                     YTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            33398..33550
                     /locus_tag="VVR21_000816"
     CDS             33398..33550
                     /locus_tag="VVR21_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054729.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            33572..34813
                     /locus_tag="VVR21_000817"
     CDS             33572..34813
                     /locus_tag="VVR21_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU6054730.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            34823..35053
                     /locus_tag="VVR21_000818"
     CDS             34823..35053
                     /locus_tag="VVR21_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6054731.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            35074..35151
                     /locus_tag="VVR21_000819"
                     /pseudo
     CDS             35074..35151
                     /locus_tag="VVR21_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            35321..36043
                     /locus_tag="VVR21_000820"
     CDS             35321..36043
                     /locus_tag="VVR21_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6054732.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            36260..37594
                     /gene="pepC"
                     /locus_tag="VVR21_000821"
     CDS             36260..37594
                     /gene="pepC"
                     /locus_tag="VVR21_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU6054733.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(37650..38561)
                     /locus_tag="VVR21_000822"
     CDS             complement(37650..38561)
                     /locus_tag="VVR21_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6054734.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(38585..39388)
                     /locus_tag="VVR21_000823"
     CDS             complement(38585..39388)
                     /locus_tag="VVR21_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU6054735.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(39416..40405)
                     /gene="manX"
                     /locus_tag="VVR21_000824"
     CDS             complement(39416..40405)
                     /gene="manX"
                     /locus_tag="VVR21_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU6054736.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(40640..41659)
                     /gene="adhP"
                     /locus_tag="VVR21_000825"
     CDS             complement(40640..41659)
                     /gene="adhP"
                     /locus_tag="VVR21_000825"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU6054737.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(42001..42813)
                     /locus_tag="VVR21_000826"
     CDS             complement(42001..42813)
                     /locus_tag="VVR21_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6054738.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            43003..44421
                     /locus_tag="VVR21_000827"
     CDS             43003..44421
                     /locus_tag="VVR21_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU6054739.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            44475..45182
                     /locus_tag="VVR21_000828"
     CDS             44475..45182
                     /locus_tag="VVR21_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6054740.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIIPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            45277..46251
                     /gene="folP"
                     /locus_tag="VVR21_000829"
     CDS             45277..46251
                     /gene="folP"
                     /locus_tag="VVR21_000829"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU6054741.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMPHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQCVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            46253..47575
                     /locus_tag="VVR21_000830"
     CDS             46253..47575
                     /locus_tag="VVR21_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU6054742.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            47556..48110
                     /gene="folE"
                     /locus_tag="VVR21_000831"
     CDS             47556..48110
                     /gene="folE"
                     /locus_tag="VVR21_000831"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU6054743.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            48153..48965
                     /gene="folK"
                     /locus_tag="VVR21_000832"
     CDS             48153..48965
                     /gene="folK"
                     /locus_tag="VVR21_000832"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU6054744.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFTNQVVEVETWLPAQVLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(49010..49327)
                     /locus_tag="VVR21_000833"
     CDS             complement(49010..49327)
                     /locus_tag="VVR21_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU6054745.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     FEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            49683..50129
                     /gene="rplM"
                     /locus_tag="VVR21_000834"
     CDS             49683..50129
                     /gene="rplM"
                     /locus_tag="VVR21_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU6054746.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            50148..50540
                     /gene="rpsI"
                     /locus_tag="VVR21_000835"
     CDS             50148..50540
                     /gene="rpsI"
                     /locus_tag="VVR21_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU6054747.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(50803..51981)
                     /locus_tag="VVR21_000836"
                     /pseudo
     CDS             complement(50803..51981)
                     /locus_tag="VVR21_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678337.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(51944..52326)
                     /locus_tag="VVR21_000837"
                     /pseudo
     CDS             complement(51944..52326)
                     /locus_tag="VVR21_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
BASE COUNT        15114 a         9916 c        11927 g        15369 t
ORIGIN      
        1 aacaatcaag acagaatatt ttggcagcct tactgaaagg atgaacaaat atcgagaaga
       61 tgttttaaat aaaaaacctt atattgatgc tgagagagca gttctagcaa cacgcgccta
      121 tgaacgatac aaggaacaac ctaatgtcct aaaacgtgca tatatgctga aagaaatttt
      181 ggaaaatatg tttatctata ttgaagaaga atctatgatt gcgggaaatc aagcttcttc
      241 caataaagat gctcctattt ttccggaata tacactagaa tttgttctca atgagttgga
      301 tctttttgaa aagcgtgatg gagatgtttt ctatattaca gaagaaacaa aagaacaact
      361 tagaagtatt gctccgtttt gggaaaataa taatttacgt gctagagctg gtgccttatt
      421 acctgaagaa gtgtctgttt atatggaaac aggattcttc ggtatggaag gtaagatgaa
      481 ttctggagat gctcacttag cagttaacta tcagaaactt ttgcaatttg gtttaagagg
      541 ttttgaagag cgggctcgta aagcgaaggt agctctagat ttaacagatc cagcaagtat
      601 tgataaatat catttttacg actctatatt tatcgtaatc gatgctatta aagtatatgc
      661 aaagcgcttt gttgctcttg ctaaaagttt agccgaaaat gcaaatccta aacgtaagaa
      721 agaattactt gagattgcag atatttgctc tagagtccca tatgaaccgg caactacttt
      781 tgcagaagct attcaatcag tttggtttat tcaatgtatt ttacaaattg aatctaatgg
      841 ccactctctt tcatatggcc gttttgatca atatatgtat ccatatatga aggctgattt
      901 agaaagtggt aaagaaacag aagatagcat tgttgaacgt ctgacaaatc tttggattaa
      961 gacaattaca attaataagg ttcgcagtca atcacataca ttttcttcag caggaagtcc
     1021 tttatatcaa aatgttacaa ttggtggaca gactcgagat aagaaggatg ctgttaaccc
     1081 attatcttat ttggtattaa aatcagttgc acaaacccat ctaccgcaac ctaatctaac
     1141 tgtacgttac catgcaggtt tagatgctcg tttcatgaat gagtgtattg aagtgatgaa
     1201 acttggtttt ggtatgcctg catttaataa tgatgagatt attattcctt cttttattgc
     1261 aaaaggagta ttggaagatg atgcttatga ttacagtgcc attggatgtg ttgaaacggc
     1321 agttccgggg aaatggggct atcgttgcac aggtatgagt tatatgaact tccctaaggt
     1381 tctacttatc acgatgaatg atggaattga tccggcttcg ggtaaacggt ttgcaccaag
     1441 ctttggtcat tttaaggata tgaagaactt ttctgaatta gaaaatgctt gggataaaac
     1501 actaagatat ttgacacgaa tgagtgttat tgttgaaaat tctattgatt tatcattgga
     1561 acgagaagtt cctgatattc tatgttcagc attgactgat gattgtattg gtcgtggaaa
     1621 acaccttaaa gaaggtggag cagtatatga ttatatatca ggattgcaag ttggaattgc
     1681 aaatttgtcg gattcattag ctgcaattaa aaaattggtg tttgaggaag aacgtataag
     1741 cccaagtcag ctttggcatg cactggaaac agattatgcc ggagaagaag gtaaggtcat
     1801 tcaagaaatg ttgattcatg atgcacctaa gtatggtaat gatgatgatt atgctgacaa
     1861 attggttact gctgcttatg acatttatgt tgatgaaatt gctaaatatc ctaatacacg
     1921 ttatggaaga gggcctattg gaggaattcg ttattcagga acatcttcta tatcagccaa
     1981 cgtagggcag ggacgtggaa cattagcaac tccagatgga cgcaacgcgg gtacaccgtt
     2041 agcagagggt tgttcaccat cacataatat ggatcaacac ggccctacat ctgttttaaa
     2101 atctgtttca aaattaccaa cagatgaaat cgtaggtggg gttctcttaa atcagaaagt
     2161 aaatcctcaa acgttagcca aagaagaaga taaattaaaa ctaattgctt tgttacgaac
     2221 attctttaat cgtttacatg ggtaccatat tcaatacaat gttgtttcca gagagacgtt
     2281 gattgacgct cagaaacatc ctgaaaaaca cagagactta attgttcgtg ttgcaggata
     2341 ctctgcattc ttcaatgttc tttctaaggc aacccaagat gacattatag gacgtactga
     2401 gcatactttg taaaataaag aggttctttt tatggaattt atgcttgaca cattaaattt
     2461 agatgagatt aaaaagtggt ctgaaatttt gccgctagct ggggtaactt caaatcccac
     2521 tattgcaaaa agagagggtt ctattaattt ttttgaacga atcaaagatg taagagaatt
     2581 gattggctcc acaccctcta ttcatgttca ggtgatttct caagattttg aaggcatctt
     2641 aaaggatgct catgaaattc gaagacaagc aggagatgat atatttatca aagtacctgt
     2701 tactccagct ggattacgtg caataaaggt gctaaaaaaa gagggctacc atatcactgc
     2761 aacagctatt tatacagtta ttcagggatt attagctatc gaagtaggag cggattacct
     2821 agctccatat tataatagaa tggaaaatct gaacattgat tcaaattctg tcattcgtca
     2881 attagctctt gctattgata gacagaactc tcctagtaag attttagctg catcctttaa
     2941 aaatgtagca caagtaaata atgctttagc tgcaggtgcg catgctgtta cagcaggagc
     3001 agatgttttt gaatcagctt tcgccatgcc atctatccaa aaggcggttg atgatttttc
     3061 tgacgattgg tttgttactc aaaatagtcg ttccatttag atagagagga aatacatatg
     3121 agaatttttg ctagtccttc tagatatatt cagggggaaa atgccttgtt tgaaaatgcc
     3181 aaatcaattt tggatttggg aaattacccg attctattat gcgatcagtt ggtttatgat
     3241 attgttggaa aacgatttga agattatcta cataggtatg gtttccatat tgttctggcg
     3301 ctatttaatg gtgaagcttc tgacaatgaa atcaatcgag ttgttgcctt ggctgagaaa
     3361 gaaaattgtg atagtattat cggtcttggt gggggaaaga cgattgatag cgcaaaagct
     3421 attgcagatt tgattgaaaa gcctgttatt attgctccaa caattgcatc gaccgacgca
     3481 cctgtatctg ctttatctgt tatttataca gatgaaggtg catttgatca ttatctattt
     3541 tattctaaaa atccagattt agttttggtt gatacaaaag ttatttcgca agcccctaag
     3601 cgtttattag cgtctggtat tgcagatggt ttagcaactt gggttgaggc gcgtgcggtt
     3661 atgcaggcaa atggaaaaac tatgttggga caacagcaaa cattggctgg agttgcaatt
     3721 gcgaagaaat gtgaagaaac gctgtttgca gatggtttac aggctatggc agcttgtgaa
     3781 gctaaagtgg tgacaccagc attagaaaat attgttgaag ctaatacttt attgagtggc
     3841 ctaggttttg aaagtggagg attagctgcg gcgcatgcaa ttcataatgg ttttactgca
     3901 ttgacaggcg acattcatca tttaacacat ggtgaaaaag tagcttatgg aactttagta
     3961 caactattat tggaaaatag acctaaagaa gaacttgata agtatattga gttttacaaa
     4021 aaaattggta tgccaacaac tctaaaagaa atgcatttgg atcaagttgg atatgatgat
     4081 ttaataaaag ttggtaaaca agcaactatg gagggtgaga caattcatca gatgccgttt
     4141 aagatttcgc cttcagatgt tgctcaagct attatcgctg tagatgccta tgtaaattca
     4201 aaataaacaa taaggactac tgttttccaa atggtagtct tttattgatc ctcgtattga
     4261 attctatagc agattgaaat aagatgagaa caaatcgatt gggaaagtaa aattaatttc
     4321 tataaatgtt ttagcaattg tttcgtacta tttcagattc agtccactat acgttcttca
     4381 taaatcaaaa agcgacatag gttgtcggct atttattgtg aatacattaa ttagcattcc
     4441 agttttatct tcggtctaaa ataagtattt tgtgctatac gagataagct tcttgactta
     4501 ctccttgatt tactgcataa caatgggata aaaagtggga gatagagcaa ttcatagtca
     4561 tcaaaattaa tgagatacag tatacagttt ttcctttaaa cacatttcaa attccctcaa
     4621 aaatggtata atagtaacat cacaaaattg gagagagacc atgagttttt acaatcataa
     4681 agaaattgag cctaagtggc agggctactg ggcagaacat catacattta agacaggaac
     4741 agatgcatca aaacctaagt tttatgcgct tgatatgttc ccttatccgt ctggagctgg
     4801 tctgcacgta ggacacccag aaggttatac tgcaaccgat atcctcagtc gttacaaacg
     4861 tgcgcaaggc tacaatgtcc ttcacccaat gggttgggat gcttttggtt tgcctgcaga
     4921 gcaatacgct atggatactg gtaatgaccc agcagaattt acagcggaaa acattgccaa
     4981 cttcaaacgt caaatcaatg cgcttggatt ttcttatgac tgggatcgtg aagtcaacac
     5041 aacagatcca aactactaca agtggactca atggattttc accaagcttt acgaaaaagg
     5101 cttggcctat gaagctgaag tgccagtaaa ctgggttgag gaattgggaa ctgccattgc
     5161 caatgaagaa gtgcttcctg acggaacttc tgaacgtgga ggctatccag ttgtccgcaa
     5221 accaatgcgc caatggatgc tcaaaatcac ggcttacgca gagcgcttgc tcaatgactt
     5281 agatgaacta gattggtcag agtctatcaa ggatatgcaa cgcaactgga ttggtaaatc
     5341 aactggtgcc aatgtaactt tcaaagtaaa aggaacagac aaggaattta cagtctttac
     5401 tactcgtccg gacacacttt tcggtgcgac tttcactgtt ttggctcctg aacatgaatt
     5461 agtagatgcc atcacaagca cagagcaagc agaagcagta gcagactaca aacaccaagc
     5521 cagccttaag tcagacttgg ctcgtaccga ccttgccaaa gaaaaaactg gtgtatggac
     5581 tggtgcttat gccatcaatc ctgtcaatgg taaggaaatt ccaatctgga ttgcggatta
     5641 cgttcttgct agctatggta caggtgcggt tatggctgtg cctgcccacg atcaacgtga
     5701 ctgggaattt gccaaacaat ttgaccttcc aatcgtcgaa gtacttgaag gtggaaatgt
     5761 tgaagaagct gcctacacag aagatggcct tcacgttaat tcagacttcc tagatggact
     5821 caacaaagaa gacgctattg ccaagattgt ggcttgcttg gaagaaaaag gctgtggaca
     5881 agagaaggta acctaccgtc tccgcgactg gctctttagc cgtcaacgtt actggggtga
     5941 gccaatccca atcattcatt gggaagatgg aacttcaaca gctgtccctg aaagtgaatt
     6001 gccacttgtc ttgcctgtaa ccaaggatat ccgtccctca ggtactggtg aaagtccact
     6061 agctaacttg acagactggc ttgaagtgac tcgtgaagat ggtgtcaaag gtcgtcgtga
     6121 aacaaatact atgccacaat gggcaggttc aagctggtac tacctccgct atattgaccc
     6181 acacaatact gagaaattgg ctgacgagga tctgctcaaa caatggttgc cagtagatat
     6241 ctacgtgggt ggtgcggaac atgctgtact tcacttgctt tacgctcgtt tctggcataa
     6301 attcctctat gacctcggtg ttgttccaac taaggaacca ttccaaaaac tctttaacca
     6361 aggaatgatt ttgggaacaa gctatcgtga ccaccgtggg gctcttgtgg cgactgacaa
     6421 ggttgaaaaa cgtgatggtt ctttcttcca tgtggaaaca ggggaagagt tggagcaagc
     6481 gccagccaag atgtctaaat cgctcaagaa cgttgtcaac ccagacgatg tggtggaaca
     6541 atacggtgct gatacccttc gtgtctatga aatgttcatg ggaccactcg atgcttcgat
     6601 tgcttggtca gaagaaggtc tggaaggaag tcgtaagttc cttgaccgtg tttaccgttt
     6661 gattagaagt aaggaaattg ttgcggaaaa caatggcgct cttgacaagg tttacaacga
     6721 aactgttaaa gctgtcacag agcaaattga ttccctcaaa ttcaacacag ccattgccca
     6781 acttatggtc tttgtcaatg cggctaacaa ggaagacaag ctctatgttg actatgccaa
     6841 aggatttatc caattgattg ccccatttgc acctcacttg gcagaagaac tctggcaaac
     6901 tgttgctgca acaggtgagt caatctctta cgtgacttgg ccaacatggg acgaaagtaa
     6961 actggttgaa gacgaaatcg aaatcgttgt ccaaatcaaa ggtaaagtcc gtgccaaact
     7021 catggtcgct aaagacctat cacgtgaaga attgcaagaa attgctctag cggatgaaaa
     7081 agtcaaagca gaaattgacg gtaaggaaat cgtgaaagtg attagtgtac caaataaatt
     7141 ggttaatatt gttgtaaaat aaccaattta tttgctgatt tccaacctca aacagtttcc
     7201 caaactgttt gagccaacta aactcgttaa tatcgttgtg aaataaggta ggaatccttc
     7261 agagtagaat ctggaggatt ttttgaatct tcttatgaaa gtatggtata ctatgggcaa
     7321 ctataaagtt tgaaaagtga aaaaaggaga aagctatgcc agtaaatgaa tatggtcaaa
     7381 tgattgggga gtcaatggaa ggttatacac caggtgaact gccttctatt gatttcttag
     7441 aagggcgtta tgctaggata gaggctcttt cagtggaaaa gcatgcggag gatttgctag
     7501 ctgtttatgg gcctgatacg cctcaggaga tgtggaccta cctttttcag gagccagtag
     7561 cagatatggg ggagctggtt agccttttac atcagatgtt ggctcgtaag gaccgttttt
     7621 actatgcaat catagacaag gcgactggta aggctttggg atctttttct ctcatgcgca
     7681 ttgaccagaa taaccgagta atagaagtcg gagcagtcac tttttctcca gagctaaggg
     7741 gtacacggat aggaactgaa gctcagtatc tcctagctcg ctatgttttt gaggagctaa
     7801 actatcgtcg ctacgagtgg aaatgcgatg ccttaaatct gccatccaga cgagctgcgg
     7861 agcgtttgag ctttatttat gaaggaacct tccgtcaggc agtggtttat aagggacgta
     7921 cgagagatac ggattggttg tctatgattg ataaggactg gcctcaagtc aaagatcgtt
     7981 tggaaacatg gttgcgtcct gaaaattttg ataaaaatgg acagcagtac aagagcttga
     8041 gagaacttta agaggtgttg acatgattac tattaaaaag caagaaattg tcaagctaga
     8101 ggatgtttta catctctatc aggctgtcgg ttggacaaat tatacccatc aaccagagat
     8161 gctggagcag gccttatctc attcattagt aatttatctg gcacttgatg gtgatgctgt
     8221 ggtgggcttg attcgtttgg ttggagatgg attctcatca gtattggttc aggatttaat
     8281 cgttttacca atctatcagc gtcaaggaat tggtagtgcc ttgatgaaag aggctttaga
     8341 ggattacaaa gatgcctatc aagtccagct ggtgacagaa gagacagaaa gaaccttggg
     8401 cttctatcgt tctatgggct ttgaaatctt atccacctat aattgtatag ggatgacttg
     8461 gatgaatcgt aaaaaataac aaaacttgtt ttttcttaag caaaatttaa ggatggtcta
     8521 gtattatata gtcattaaat aaagacctcc taactttatt taataaaatc ctaaactttt
     8581 ctttttcata ataatctccc ttaactccac ccaatcaggt ggagtttttt agctctattt
     8641 caggcttttg gggactattc taaaaataat ttttcgatat ttttcggtat ttttcggatt
     8701 ttggtcgggg aattggcggg gactttttta gcgaatataa ctaagaaata ggtctgtggt
     8761 cgcttcagct agttcaaact caatttgatt gtaagtgact gttaattgaa gaactggaac
     8821 tactgtaata atgattttgc ttgtctagta gtggcgtatt aaatgagaag tgacatgtaa
     8881 gattgtcgct tcgtttacga aatcaaaatt tctatgaaat tgatagaatc cctaacgttc
     8941 tcttaatctt aaccgtcttg tcgtacagcg gttgaagaaa atgtaaacct ttgacaaaat
     9001 tcgtgaacta tgggataata aaaaggaatt gagtactagt tctatatcat aggctagaaa
     9061 agaccccaag ctcacgacca aataagcttg aggtcttttt tgacactatt tgtccttgtt
     9121 tagccattta tcgactatac gaagaacgac accgaccaca attggtccga tgatagtttt
     9181 gagtactaat tccatcatgg gctatctcac ctcctttcgt aggcggtgta gcagtgtcgt
     9241 agaatattat accacataag tgctaaactt aggagtcacc caatcaggtg gcttttttgt
     9301 ttgtggcttg gttttttgat ataatagagc catgagtaga attttagata atgagataat
     9361 gggggatgag gagttagtag aacgcacgct ccgtcctcag tatttacgtg aatatatcgg
     9421 acaggataag gtcaaggacc agctacaaat ctttattgaa gctgccaaaa tgcgggatga
     9481 agcgctggat catgtgctct tatttgggcc tccaggtctc gggaaaacga ccatggcctt
     9541 tgttattgcc aacgaactgg gagtcaatct taagcagacg tcgggtccag tcattgaaaa
     9601 agccggagat ctggtagcta ttttgaatga gttagagcct ggggatgtcc tttttattga
     9661 tgagatccat cgtttgccaa tgtcagtgga agaggtgctt tatagtgcta tggaggactt
     9721 ctacatagat attatgattg gggctggtga gggtagtcgt agtgttcatt tggagttacc
     9781 accttttacc ttgattggtg cgacgactcg ggctggtatg ctctccaatc cgctacgggc
     9841 acgttttggg attacaggcc atatggagta ttatgcccat gctgacttga cagaaattgt
     9901 cgagcggacg gcagatattt ttgagatgga aatcactcat gaggcagcat ctgagttggc
     9961 cctacgtagt cgtgggaccc ctcgtattgc caatcgtctc ctcaagcgcg tgcgcgattt
    10021 tgcccagata atggggaatg gggtaattga tgatattatt accgataagg ctttgactat
    10081 gctggatgtt gaccatgaag gtttggacta tgtggatcaa aaaatccttc gtaccatgat
    10141 tgagatgtac agtggaggac ctgttggtct aggaactctt tctgtgaata tcgccgaaga
    10201 gcgtgagaca gttgaagata tgtatgagcc ttacttgatt caaaaaggtt ttatcatgcg
    10261 gacacggtct ggacgggtgg cgactgctaa ggcatatgag cacttaggtt atgaatacag
    10321 tgaaaaataa gcaagaaatc ttagaggctt ttagagaaaa tccagatatg atggccattc
    10381 tgacgatcat ccgagacctt ggtctgaaag actcgtggtt ggcagcaggt tctgtcagaa
    10441 atttcatttg gaatcttttg tcagacaaat ccccttttga tcatgaaaca gatatagatg
    10501 tgattttctt tgatccagat ttttcttatg aggaaacctt attactggag aaaaagctgc
    10561 gagaggattt tcctcagtac cagtgggaat tgaaaaatca ggtctatatg catcagcaca
    10621 gtcctcacac tgcttcctat accagttctc gtgatgctat gagtaagtat ccagaacggt
    10681 gtacgacagt tggactgcgc ttgaatgaag aatcagattt tgaactctat gcaccttatg
    10741 gtttggagga tattttgaat tttcaagttc gtccaactcc tcatttctta gaaaatgaag
    10801 accgaatgga actctatcaa acacgtttat ccaagaaaaa ttggcaggag aaatggaaaa
    10861 atttgatttt taaaaatact taaggaaact ttaagctagg gagtgtacac taagttcata
    10921 agttaagaag accttaactt aaactcctaa aactttttca taataatctc cctataaaaa
    10981 taaagtcgcc caatcaggcg gcttattttt ttgaaaaatg ggcttggtgc ctgagaataa
    11041 atagcttagt gatagaagaa aatggggaaa tatggtataa taaaacgata gatttttgaa
    11101 taggaataag atcatgtttg gattttttaa gaaagataag gctgtggaag tagaggttcc
    11161 gacacaggtt cctgctcata tcggcatcat catggatggc aatggccgtt gggctaaaaa
    11221 acgtatgcaa ccgcgagttt ttggacataa ggcgggcatg gaagcattgc aaaccgtgac
    11281 caaggcagcc aacaaactgg gcgtcaaggt tattacggtc tatgcttttt ctacggaaaa
    11341 ctggacccgt ccagatcagg aagtcaagtt tatcatgaac ttgccagtag agttttatga
    11401 taattatgtc ccggaactac atgcgaataa tgttaagatt caaatgattg gggagacaga
    11461 ccgcctgcct aagcaaacct ttgaagcttt aaccaaggct gaggaattga ctaagaacaa
    11521 cacaggattg attcttaatt ttgctcttaa ctatggtgga cgtgctgaga ttacacaggc
    11581 gcttaagttg atttcccagg atgttttaga tgccaaaatc aatccaggtg acatcacaga
    11641 ggaattgatt ggcaactatc tctttaccca gcatttgcct aaggacttac gagacccaga
    11701 cttgattatc cgtactagtg gagaattgcg tttgagcaat ttccttccat ggcagggagc
    11761 ctatagtgag ctttatttta cggacacctt atggcctgat tttgacgaag cggccttgca
    11821 ggaagctatt cttgcctata atcgtcgtca tcgccgattt ggaggagttt aggaggaaat
    11881 atgacccagg atttacagaa aagaaccttg tttgcaggga ttgccctggc tattttccta
    11941 ccaattttaa tgattggggg cctcttgctt cagatagcaa tcggaatcat agctatgcta
    12001 gccatgcatg aacttttgaa gatgagaggt ctagagacca tgacgatgga gggcctcttg
    12061 accctctttg caacctttgc attgaccatt cccttggaga attacctgac ttttttgcca
    12121 gttgatggga atgtggttgc ctatagtgtt ttgatttcaa tcatgttagg aacgaccgtt
    12181 tttagcaagt cttatacgat tgaggatgcg gttttccctc ttgctatgag cttctacgtg
    12241 ggctttggat ttaatgcttt actagatgct cgtgttgcag gtttggacaa ggctctctta
    12301 gccttgtgta tcgtctgggc gacagacagt ggtgcctatc ttgttgggat gaactatggg
    12361 aaacgaaagt tagcaccaag ggtatcgcct aataaaaccc ttgagggtgc cttgggtggt
    12421 attttaggag caattttagt aaccattatc tttatgatag ttgacagtac agttgctctt
    12481 ccatatggaa tttacaagat gtcagtcttt gctattttct ttagcattgc tggacaattt
    12541 ggtgatttac tagaaagttc gatcaaacgt cattttggtg ttaaggattc tgggaaattt
    12601 atccctggac atggtggtgt tttggatcgt ttcgatagta tgttgcttgt atttccaatc
    12661 atgcacttat ttggactctt ttaatcaaaa gacggaggaa acgctatgct cggaatttta
    12721 acctttattc tggttttcgg gattattgta gtggtgcacg agttcgggca cttctacttt
    12781 gccaagaaat cagggatttt agtacgtgaa tttgccatcg gtatgggacc taaaattttt
    12841 gctcacattg gcaaggatgg aacggcctat accattcgaa tcttgcctct gggtggctat
    12901 gtccgcatgg ccggttgggg tgatgataca actgaaatca agacaggaac gcctgttagt
    12961 ttgacacttg ctgatgatgg taaggttaaa cgcatcaatc tctcaggtaa aaaattggat
    13021 caaacagccc tccctatgca ggtgacccag tttgattttg aagacaagct ctttatcaaa
    13081 ggattggttc tggaagaaga aaaaacattt gcagtggatc acgatgcaac ggttgtggaa
    13141 gcagatggta ctgaggttcg gattgcacct ttagatgttc aatatcaaaa tgcgactatc
    13201 tggggcaaac tgattaccaa ttttgcaggc cctatgaaca attttatctt aggtgtcgtt
    13261 gttttttggg ttttaatctt tatgcagggt ggtgtcagag atgttgatac caatcagttc
    13321 catatcatgc cccaaggtgc cttggccaag gtaggagtac cagaaacggc acaaattacc
    13381 aagattggct cacatgaggt tagcaactgg gaaagcttga tccaagctgt ggaaacagaa
    13441 accaaagata agacggcacc gactttggat gtgactattt ctgaaaaggg gagtgacaaa
    13501 caagtcactg ttacacccga agatagtcaa ggtcgttacc ttctaggtgt tcaaccgggg
    13561 gttaagtcag attttctatc catgtttgta ggtggtttta caactgctgc tgactcagct
    13621 ctccgaattc tctcagctct gaaaaatctg attttccaac cggatttgaa caagttgggt
    13681 ggacctgttg ctatctttaa ggcaagtagc gatgctgcta aaaatggaat tgaaaatatc
    13741 ttgtacttct tggcaatgat ttccattaat attgggattt ttaatcttat tccgattcca
    13801 gccttggatg gtggtaagat tgtgctcaat atcctagaag ccatccgccg caaaccattg
    13861 aaacaagaaa ttgaaaccta tgtcaccttg gccggagtgg tcatcatggt tgtcttgatg
    13921 attgctgtga cttggaatga cattatgcga ctctttttta gataatcgag gaatattatg
    13981 aaacaaagta aaatgcctat cccaacgctt cgcgaaatgc caagcgatgc tcaagttatc
    14041 agccatgctc ttatgttgcg tgctggttat gttcgccaag tttcagcagg tgtttattct
    14101 tatctaccac ttgccaaccg tgtgattgaa aaagctaaaa acatcatgcg ccaagaattc
    14161 gaaaagattg gtgctgttga gatgttggct ccagcccttc ttagtgcaga attgtggcgt
    14221 gaatcaggtc gttacgaaac ctatggtgaa gacctttaca aactaaaaaa ccgtgaaaaa
    14281 tcagacttta tcttaggtcc aactcacgaa gaaaccttta cagctattgt ccgtgattct
    14341 gttaaatctt acaagcaatt gccactcaac ctttatcaaa ttcagcccaa gtatcgtgat
    14401 gaaaaacgcc cacgtaatgg acttcttcgt acacgtgagt ttatcatgaa ggatgcttat
    14461 agtttccacg ctaactatga tagtttggat agtgtttatg atgagtacaa agcagcctat
    14521 gagcgtattt tcactcgtag tggtttagac ttcaaggcta ttattggtga cggtggagcc
    14581 atgggtggta aggatagcca agaatttatg gccattacat ctgctcgtac agaccttgac
    14641 cgctgggttg tcttggacaa gtcagttgcc tcatttgacg aaattcctgc agaagtgcaa
    14701 gaagaaatca aggcagaatt gctcaaatgg atagtctctg gtgaagatac cattgcttac
    14761 tcaagtgagt ctagctatgc agctaactta gaaatggcaa caaacgagta caaaccaagc
    14821 aaccgtgtta tcgctgaaga agaagttatt cgtgttgcaa cgccagatgt taaatcaatt
    14881 gatgaagttg cagccttcct caatgttcca gaagaacaaa cgattaaaac cctcttctac
    14941 attgcagatg gtgagcttgt tgcagccctt ctagttggaa atgaccaact caacgaagtc
    15001 aagttgaaaa atcacttggg agcagatttc tttgacgttg ctagcgaaga agaagtggcg
    15061 aatgttgttc aagcaggatt tggttcactt ggaccagttg gtttgccaga gaatattaaa
    15121 attattgcag atcgtaaggt gcaagatgtt cgcaatgcag ttgtcggtgc taacgaagat
    15181 ggctaccact tgactggtgt gaacccaggc cgtgatttta ctgcagaata tgtggatatc
    15241 cgtgaagttc gtgagggtga aatttcccca gatggacaag gtgtccttaa ctttgcgcgt
    15301 ggtattgaga tcggtcatat tttcaaactc ggaactcgct attcagcaag catgggagca
    15361 gatgtcttgg atgaaaatgg tcgtgctgtg ccaatcatca tgggatgtta cggtatcggt
    15421 gtcagccgtc ttctttcagc agtgatggag caacatgctc gcctctttgt taacaaaacg
    15481 ccaaaaggtg aataccgtta cgcttgggga atcaatttcc ctaaagaatt ggcaccattt
    15541 gatgtgcatt tgattactgt taatgtcaag gatgaagaag cgcaagcctt gacagaaaaa
    15601 cttgaagcaa gcttgatggg agctggttat gaagtcttga cagatgaccg taacgaacgt
    15661 gtcggtgtta aatttagcga tagtgacttg attggtcttc caatccgtat cactgttggt
    15721 aaaaaagcgg ccgatggcat tgtagaagtt aagatcaagg caactggtga caccattgag
    15781 gttcatgcag ataacgtgct tgaaacgctt gaaatcctaa gcaagaaata aaaactataa
    15841 tcagaagaaa aacaaggaaa aaatgtaact agtttttacc ttgttttttc tgtataatgg
    15901 gagaaatgag tagataaaga ggtaaatgta tgctaagatt tccaaaggat tttgtctggg
    15961 gatcctctac ttctggaccg cagacagaag gacgtgtagc tggtgacggt aagggagaca
    16021 atctctggga ttactggttc caagtggagc caaatcgtta ctataatggg attggttcag
    16081 ataagacatc gactttttat gaaaattggg agcgggatat tgagcttttg ttagagactg
    16141 gtcacacagc ctttcggact tctattcagt ggtcacggat ttttccacaa ggctgtggaa
    16201 aagtcaacac tcaaggtgtg gatttttatc gtaaggtctt tgaggctatt aaggctaaag
    16261 gaattcgtct gttagtcaat ctctatcatt ttgatttacc ttttgccctt caagaggatg
    16321 gtgatggttg ggaaaataag gcgacagtct cagcctatga agactatgct cgtttttgtt
    16381 ttgagactta tggagattta gtggatcaat ggattacctt taacgagccc atcgttcctg
    16441 tagaatttgg ttatttttat gatgcccatt atccacataa ggtggatgca gaggcagctg
    16501 ttaaggtagc ctatcataca caattggcca gcagccgggc tgttaaggct tgccatgaac
    16561 ttttgcctga ttccaagatt gggattgtcc tcaacttgac accggcttat ccacgtagcc
    16621 agcatcctgc tgatgtcaag gcagctcgta ttgcggccct ttttcaggcc caatctttct
    16681 tagatccatc tgtcttgggg acttatccac aggagttggt agaaatcttg catgaacacg
    16741 gtcttttacc tgatgctaca gaggaagagt tggaactcat tcgtgataat acggtggact
    16801 tccttggtgt gaactactat caacctttgc gtgttatggc tcctcgattt gctaagcatc
    16861 cagagagtcc actcttacca gaacattttt acgagcctta tgtgatgcct ggacgtaaaa
    16921 tcaattctca ccgtggttgg gagatttatg agcaagggat ttatgacatc gcccaaaata
    16981 tcaaggaaaa ttatggcaat attgagtgga tgttgactga gaatggtatg ggtgttgaag
    17041 gggaagaaaa attccgtcaa gatggaatga ttcaagatga ttaccgtatt gactttgtaa
    17101 aaggtcatct tcgtgaactt caccgtgcca ttgaagatgg tgccaactgt aagggctact
    17161 tgatttggac ctttattgac tgctggtcat ggctcaacag ctataaaaat cgctatggtt
    17221 tggtcgaatt agacttggaa acgcaagaac gtcgtctgaa gaaatcaggc cactggttca
    17281 aagaattaag cgataataat ggattttaaa aaggactctg actgattatc ccaatcggtc
    17341 agagttttta tgcttacagg agcttaattt gaactatacc aatttttact cttgacaagt
    17401 gaaagaaaca agtatatact gtttttgctg attctataaa agatgaatta gactatacca
    17461 attttaagga gaaagcacag cttgcctgtg tcgtatatac tatgtgtgga attgttggtg
    17521 ttgttggaaa cacaaatgca actgatattt tgattcaagg gcttgaaaag cttgaatacc
    17581 gtggctatga ttctgcggga atttttgtcc tagatggtgc tgataaccat ttggtgaagg
    17641 cggttggtcg tattgcagaa ctgtctgcca agacagctgg tgttgaggga acaactggta
    17701 tcggacatac tcgttgggct actcacggaa aaccaactga ggacaatgct cacccacacc
    17761 gctctgagac agaacgtttt gtcttggtgc ataatggggt gattgagaac tatcttgaaa
    17821 tcaaggaaga ataccttgca ggtcaccact tcaaggggca gacagatact gaaatagccg
    17881 ttcatttgat tggaaaattt gcggaagaag aagggctctc agttcttgaa gccttcaaaa
    17941 aagcccttca catcatccgt ggttcttatg cctttgcctt ggttgactca caagatcctg
    18001 aagtcatcta cgtagctaaa aataaatcac cacttttgat tggtcttgga gaaggctata
    18061 acatggtctg ctcagacgcc atggctatga ttcgtgaaac taaccaatac atggaaatcc
    18121 atgaccaaga gttggtaatc gtcaaggctg atagtgtgga agttcaagac tatgatggaa
    18181 atcgtcgtga gcgtgctagc tacactgctg aacttgactt gtcagatatc ggtaagggaa
    18241 cttaccctta ctacatgctc aaggaaattg acgagcaacc aactgttatg cggaaactca
    18301 tccaagccta cacagatgag gctggtcaag ttgtcgtaga cccagatatc attaaggctg
    18361 ttcaagacgc agaccgcatc tacatccttg cagctggaac atcttaccat gcaggatttg
    18421 cttctaagaa aatgttggaa gaattgacag atacaccagt tgaacttggc atctcatctg
    18481 agtggggcta cggtatgcca cttctcagca agaaaccact cttcatcttt atcagccaat
    18541 ctggtgaaac agcggatagt cgtcaagttt tggtcaaggc taatgaaatg ggaattccaa
    18601 gcttaacagt gacaaatgtt ccaggctcaa ccctctcacg tgaagccaac tataccatgc
    18661 tccttcacgc aggtcctgaa attgccgtgg catcaactaa agcctataca gcgcaaatcg
    18721 cagcccttgc cttccttgca aaagcagtcg gagaagcaaa tggtaatgct aaagcgcaag
    18781 cctttgacct gattcatgaa ttgtcaatcg tagctcagtc tatcgaatca actctttcag
    18841 agaaagaaac cattgaagcc aaggttcgtg aacttcttga aacaactcgt aacgcctttt
    18901 acatcggacg tggtcaagat tactacgtag ccatggaagc aagtctcaaa ctcaaagaga
    18961 tttcttatat ccagtgtgaa ggctttgctg caggagaact caagcacgga accattgcct
    19021 tgattgaaga aggaacgcct gttttggctc tcttgtcaga tccagttctt gccaatcata
    19081 ctcgtggaaa tatccaagag gtcgcagccc gtggtgccaa agtcctcact atcgcagaag
    19141 agaatgtagc caaagatacc gacgatatcg tccttacgac cgtacatcca tacctctcac
    19201 caatttcaat ggtcgtacca acgcaattag tcgcttactt tgcaaccctc caccgtggcc
    19261 tcgatgtgga caaaccacgt aaccttgcca agtcagtaac ggtagaataa gctaaaaaag
    19321 tctagttatc taggcttttt cttgtgagca aattggttgc ttgtactcaa gattcgtgtt
    19381 agaataattt ttcaaattga aggacagaga tagacaagga gaatcacaat ggtagaattg
    19441 ggaatttcaa catttgggga aataacggag cttgaaggga ctggacaaac ttacagtcat
    19501 gctgaacgca ttcgccagtt ggtggcagag attgagctgg ctgacaaggt tggtttggac
    19561 gtatatggga ttggcgagca ccatcgggcg gattttgcag tatcagcccc agagattgtc
    19621 ctggccgctg gggcagtcaa taccaagaaa atccgtttga ccagtgcagt cagcattctg
    19681 tcaagcatgg acccgattcg tttgttccaa cagtatgcca ctatcgatgc tttgtcaaat
    19741 ggacgagcgg agattatggc tggaagggga tctttcacgg aatctttccc tctgtttggt
    19801 tatgacttga aagactacga ctctcttttt gatgagaaat tagacttgct tcagttagtc
    19861 aatgaaaaga ccaagttaga ctggcaaggt cgattgactc aaacgattgc tggtaaagaa
    19921 gtttatcctc gtccagttca ggacaaattg cccttgtgga tagctacagg tggtcatgtc
    19981 gaatcaacag tgaagattgc tcaggctggt ctaccgattg tatatgctat tattggtggt
    20041 aatccacgtt attttaaaaa gttgattcag gcttatcgtg agattggaag cgaagcgggc
    20101 catgctgaca aagacttgaa agtgggagcc cattcttggg ggtggattgc ggaagatggt
    20161 gagcaggcgg tgaaagatta tttccatccg actaagcaag tggtggatgc tatttccaaa
    20221 gaccgtccgc actggcagga attgcgttat gagcaatatt tggagcaggt agggtcaaat
    20281 ggcgccatgt ttgttggcaa tccagatcag gtggccgaaa aattgattcg catgatagag
    20341 gatttaggat tggaccgctt catgcttcat ctaccgcttg gttctatgcc tcatgaccag
    20401 gttctgagag ctattgaact cttcggaaca caagttgcac ccaaagtacg agcttatttt
    20461 gctatgaaag aggcttaata aaaaatccta atcaagttta ttaggacaac aaatattgta
    20521 cgaaaattaa tcccccgagc tataatgctt gggggatttt tctataggag ggctagctta
    20581 gttctctttt ttatttttta gtaagaaacc gagaccaagg agcgcaagga ggctgattcc
    20641 tgcaaatagg agtttgtttt cgtttttgat tcctgtattt ggaagttcag cttgtctatc
    20701 tggggttgca gatatatttt ccttgctaga gttttctacc gattcttttc gaaccgcttc
    20761 ttttacagat gatgcttgtg cttcttgtgc tggttgttca gcttgtgaat cagctgtagc
    20821 ttggctaggt ttattttccg catcagctac tttggcatct ggtttagtag aatcaggtct
    20881 agcttctgga gctgggtctt gatgtgcagg gtgagaagct tcattttgat gttcaggctt
    20941 ggaaggggtt gagtctggtt tctcttctgc agttgactca tggctagttc cattttgaga
    21001 gactcgaaga acagtagctg taagggcatt caatttcaag cctttttcag tccattcaag
    21061 tcctttcggg ttggcaattc cgactgatcc tgcttggttt tcatctgcca aaacttccgc
    21121 atttcttaga tgtgcaaagg cagttcccaa attaaattcg cgagcttttt catccgcatt
    21181 gacaaagact gcgtagatat cgccgtttgg agcagtgatt tgatagccaa tcactacatc
    21241 ctctttttcc acaccatttt ggcctgggac agtgatgagg tggacacggt ctttgatatc
    21301 ttgaagactc ttaagtcgga aggcatctgt agattgacga agggcaatca aacctttcat
    21361 atagtcacgg ctcttgacat tttcaggata agctttacca tctgtagcct tagtccagtc
    21421 aaacttgttg actgcatcac tagaatcgta agagtcatgg atgaagtaag gatagtcaaa
    21481 tgggttgccg tccttatcac gcaacaagtg agatttgttt ggaaccttat cctctgctac
    21541 tggagtcttg taggctgggt cacggaattg tttagtacgt ccatattcct gaccggagtg
    21601 gataaatgga gttccttgag ctgtcaagac catgagattt ccaagtcgta aacgacggtg
    21661 gatttcagca tagttctcag ccttgcttgg gtcttttttg atagactggg caatgatgtc
    21721 aaagagggtc aagttatcat gggctgcgat gtattggatg acatctccag ggctgtcagc
    21781 ttcaaagtta gttggttgag caatgagatt tttaaagatg gtgttgacat cacgcttgcc
    21841 acctgtgata aaggcaggtt gaccttcgtt tggataacca gatttgaggt tgttacggat
    21901 gtcatctgaa aagacagcga cagtatcggt atgtttcatc caatcttggt cagcagcttt
    21961 agtaggcatg ttttcatcac cggcataggt tctccaacct tcgcctaaca tgattagatt
    22021 tggattgagg gcgcgtgcag ccttgtaagc ttcttcgata gaagcggcgt catggtctcc
    22081 catcatatcg aagcggaagc catccacttt gtaggtatca actaggtatt tgatagagtc
    22141 aactaggagc cgtttggtca tatggtgggt tgtccccaag cgtccaccac caaagctagt
    22201 tcgaggtgtg ccatcggcat ccataaagtg gtagtagttt ggctctaggt cttcaaagat
    22261 atcgactttg gctgtgtggt tataaacgac atctaggata gctcccatac cacgtttgtg
    22321 gatttcgttg atgaggtttt taaattctgc gattcgtttt tctggattct taggatcgct
    22381 tgagtacata ccagtcaagg agaagtagtt ttgagggtca tatccccagt tgtagttgct
    22441 gttgcttgaa gcatagtcag acaagcgttc atggtttttc aattcattga caaagtagta
    22501 agacaagact ggaaggagct ggatatgggt tacacccaag tctttgagat agtctagttt
    22561 ttcaatgaag gcttcaaaag tcccaaatgg tttggtcaag tcttttgcaa tggcaggatc
    22621 tgaagtgaag tcacgcacat gagcttcgta gataacggcg tcttcacgag tcttgaaatt
    22681 gtgaatctta ccataagtca agtcttgagg tccgagttta gctggatcta caaaggcggc
    22741 tttagccact ttatgggcat cgtcaatctt ggcatcgtcg ctattccaag cagcaagaga
    22801 tttagcgtaa ggatcgagtg caagaacagt tttaccttga cgctcgattt ggtattgata
    22861 atagtagcca gtgaaatctg tgattccgag tttgtttgtg ctgtctagag tttgtttcca
    22921 agttcctctt tccccttttt cgagagcgac agttccaact actttgtcag ggtcattctt
    22981 gtcgtagaca acaacagaaa ccttatcagc acttggtgac caaagggtca aatcaacttg
    23041 ttttccttct tcttttaggt cagctcccag tttgccatca tagctgtatg tctcatcttt
    23101 caggcgccag cttgttttgg tagtgaattg gtcggaattg tagctaacag tataaggatg
    23161 ttttgtgtca gagaaatctc cgctgtaggt cactttctta ccagcttcat cgattgcaac
    23221 atcggtaata gttaccttgt ttcctaggtg attagtgatg ttggagtgtt tgaggatatc
    23281 ttctttttta gcaccgacaa gtgttgaaaa gctactttca atgctagaag tgcctacgtg
    23341 ttgggctcct gtcatacgga tatcatggac atagtatgga tttgtgtaaa tcgattcatc
    23401 atcgtctttt aggaaaattt ggctatgatt tttcaaatct gtgaacttat aattttcttt
    23461 acggattttc acgtcgtctc cttgtttgct ctcatctagt aataaaaatc caaattctct
    23521 tgcggcttca ttaagaggaa tgtcgatata gcggccatat ttgcctgtag ccgtaaagtc
    23581 tgttccgtca ggccattgag cgctacttgg attttttaca tctccccagt accagagaga
    23641 tttcttgtca tagttgccat ctgtgcggta gtagttgacg cgaatagttc ctgcaggctg
    23701 tggctcgtaa gagaaaacct tgtaatcttg gtctaaccaa gcttcgttca tttttggaac
    23761 tagtttttct acagatttat cgccggttag attttttcca gctgtattgt tgatgaggaa
    23821 gctaattttc ttggcttgtt ctccctttaa tttgacatct aggtaatagc cgtagtcatc
    23881 tttcttggca tccttgaagg acaaagctcc gtttggccag ttttcagatg gtttttcaac
    23941 atcgtcccaa gtccatagtc cttgagcatc cttgttttct tcaggaagtt ttttgacatg
    24001 gatacggaag tagttatctt cgatgggctc ttctgcctta gtttcagttg ttactggact
    24061 agtagaagta gttggctcac ttgaacgatc ttgtccagtt tgtggtgctg aatcggctgg
    24121 gcttgcagca ggtttttctt ctgttttctc tagggaagcg tttgcatttc taggtgaaga
    24181 aatatcactt tcgttcttac cagagccagc tgctgtatca gtaagaggtt gggcaagggt
    24241 ggttgtattt ctgttgttgg gttcgttagt ggttggtgta ctttcgtcgg atgagatagt
    24301 tggtgtagcc atggcaagca agacaaggct tgcgccgata aggacagaac cagttccatt
    24361 tttgagggaa cggatgctgt agaccatttt tttctcagtg tgagatggtg tttttctcat
    24421 aatgattctc caatcaataa atttctatat cagtatagca tgtagtaaaa caatatgcaa
    24481 gcgttttctt tgatttgtga aaaaaattcc tacttttgag aagttttctg tactatttta
    24541 tatatcagta taaatgacgg agataaaaat gtcacataag ccaagccgta ttattaggaa
    24601 gatgatgtgt tcccagctat ttttattcag aaattgatct ctaacattac caataaaaaa
    24661 gaaaaatatc ttgacaagca agggaaaatt ttgttacaat aatagacggt actttttact
    24721 tttggtctct caagagtgta cagggacgtg ctgacaaatg ttgcaaaagt acacacagat
    24781 gatatctgtc accaagtgta tcatcaccaa aaataaaaaa acacaggaga atgtagatgc
    24841 ctacaattaa ccaattggtt cgcaaaccgc gtaaatcaaa agtagaaaaa tctaaatcac
    24901 cagctttgaa cgttggttac aatagtcata aaaaagttca aacaaacgtt tcttcaccac
    24961 aaaaacgtgg tgttgcaact cgtgttggaa caatgacacc taaaaaacct aactcagccc
    25021 ttcgtaaatt cgctcgtgta cgtttgagca accttatcga agttactgcc tacatcccag
    25081 gtatcggaca caacttgcaa gagcacagcg tggtgcttct tcgcggtgga cgtgtaaaag
    25141 accttccagg ggtacgttac catatcgtcc gtggtgcact tgatactgca ggtgttaacg
    25201 atcgtaaaca aggccgttct aaatacggta ctaaacgtcc aaaagcataa ggaaagggga
    25261 taaagagaaa tgagtcgtaa aaatagagct ccaaaacgtg acgtattgcc agatccgcta
    25321 tacaattcac aactagttac tcgtcttatc aaccgcgtta tgcttgatgg taaacgtggt
    25381 actgctgctt caatcgttta cggtgctttt gagcaaatca aagaagctac tggcaacgat
    25441 gcacttgaag tatttgaaac agctatggaa aacatcatgc ctgtacttga agtacgtgca
    25501 cgtcgtgttg gtggttctaa ctaccaagtc ccagttgaag ttcgtccaga acgtcgtaca
    25561 acacttggac ttcgttggtt ggtaacaatc gctcgtcttc gtggtgaaca cacaatgcaa
    25621 gaccgtcttg caaaagaaat cttggatgct gctaacaaca ctggtgcagc agttaagaaa
    25681 cgtgaagata ctcaccgtat ggctgaagct aaccgtgcat tcgcacactt ccgttggtaa
    25741 gataggatgc gaaagcgtta agaaagtccc agagaaaata gggaatcgaa gcaggttgcg
    25801 gttgcaacca atgagattca tctttttctc cagactttta gcttgagctc aactaaatca
    25861 tgatgctagg cacggtaagg atgcaaggtg aaaataggaa actgacgcag tattcaacga
    25921 atacaaggag ttttatcttt ttcacgcaac atcccgttcc agctcacatc ggctaactaa
    25981 ctttagcctg ggttcaaatt agctaaatcg attagtatta gctataactc agcttaccat
    26041 ctcgtaagtt gaaaccaaca atagcatgaa aacattgaga acgggtaggt cctgcctatc
    26101 cgtttttatt aaaatcgtgt tataatagaa tagaaatcaa aaataaatag gagaaacaaa
    26161 cctcatggca cgcgaatttt cacttgaaaa aactcgtaat atcggtatca tggctcacgt
    26221 cgatgccggt aaaacaacaa ctactgagcg tattctttac tacactggta aaatccacaa
    26281 aatcggtgaa actcacgaag gtgcgtcaca aatggactgg atggagcaag agcaagaacg
    26341 tggtatcacg atcacatctg ctgcgacaac agctcaatgg aacaaccacc gcgtaaacat
    26401 catcgacaca ccaggacacg tggacttcac aatcgaagta caacgttctc ttcgtgtatt
    26461 ggatggtgcg gttaccgttc ttgactcaca atcaggtgtt gaacctcaaa ctgaaacagt
    26521 ttggcgtcaa gcaactgagt acggagttcc acgtatcgta tttgccaaca aaatggacaa
    26581 aatcggtgct gacttccttt actctgtaag cacacttcac gatcgtcttc aagcaaatgc
    26641 acacccaatc caattgccaa tcggttctga agatgacttc cgtggtatca ttgacttgat
    26701 caagatgaaa gctgaaatct atactaacga ccttggtacg gatatccttg aagaagacat
    26761 cccagctgaa taccttgacc aagctcaaga ataccgtgaa aaattgattg aagcagttgc
    26821 tgaaactgac gaagaattga tgatgaaata cctcgaaggt gaagaaatca ctaacgaaga
    26881 attgaaagct ggtatccgta aagcgactat caacgttgaa ttcttcccag tattgtgtgg
    26941 ttcagccttc aaaaacaaag gtgttcaatt gatgcttgat gcggttatcg actaccttcc
    27001 aagtccactt gacatcccag caatcaaagg tattaaccca gatacagacg ctgaagaaat
    27061 tcgtccagca tctgacgaag agccatttgc agctcttgcc ttcaagatca tgactgaccc
    27121 attcgtaggt cgcttgacat tcttccgtgt ttactcaggt gttcttcaat caggttcata
    27181 cgtattgaat acttctaaag gtaaacgtga acgtatcgga cgtatccttc aaatgcacgc
    27241 taacagccgt caagaaatcg acactgttta ctcaggtgat atcgctgctg ccgttggttt
    27301 gaaagatact acaactggtg actcattgac agatgaaaaa gctaaaatca tccttgagtc
    27361 aatcaacgtt ccagaaccag ttatccaatt gatggttgag ccaaaatcta aagctgacca
    27421 agacaagatg ggtatcgccc ttcaaaaatt ggctgaagaa gatccaacat tccgcgttga
    27481 aacaaacgtt gaaactggtg aaacagttat ctcaggtatg ggtgaacttc accttgacgt
    27541 ccttgttgat cgtatgcgtc gtgagttcaa agttgaagcg aacgtaggtg ctcctcaagt
    27601 atcttaccgt gaaacattcc gcgcttctac ccaagcacgt ggattcttca aacgtcagtc
    27661 tggtggtaaa ggtcaattcg gtgatgtatg gattgaattt actccaaacg aagaaggtaa
    27721 aggattcgaa ttcgaaaacg caatcgtcgg tggtgtggtt cctcgtgaat ttatcccagc
    27781 ggttgaaaaa ggtttggtag aatctatggc taacggtgtt cttgcaggtt acccaatggt
    27841 tgacgttaaa gctaagcttt atgatggttc atatcacgat gtcgactcat ctgaaactgc
    27901 cttcaagatt gcggcttcac tttcccttaa agaagctgct aaatcagcac aaccagctat
    27961 ccttgaacca atgatgcttg taacaatcac tgttccagaa gaaaaccttg gtgatgttat
    28021 gggtcacgta actgctcgtc gtggacgtgt agatggtatg gaagcacacg gtaacagcca
    28081 aatcgttcgt gcttacgttc cacttgctga aatgttcggt tacgcaacag ttcttcgttc
    28141 tgcatctcaa ggacgtggta cattcatgat ggtatttgac cactacgaag atgtacctaa
    28201 gtcagtacaa gaagaaatta ttaagaaaaa taaaggtgaa gactaatccg tcctcactct
    28261 agaaggaagt cacttagtgg cttccttttg tctttagaaa atacctctaa atatggtaaa
    28321 atagtagaag aataatgtga ggaaaatgaa tgtcaaatag ttttgaaatt ttgatgaatc
    28381 aattggggat gcctgctgaa atgagacagg ctcctgcttt agcacaggcc aatattgagc
    28441 gagttgtggt tcataaaatt agtaaggtat gggagtttca tttcgtattt tctaatattt
    28501 taccgattga aatcttttta gaattaaaga aaggtttgag cgaagaattt tctaagacag
    28561 gcaataaagc tgtttttgaa attaaggctc ggtctcaaga attttcaaat cagctcttgc
    28621 agtcctacta tagggaggct ttctctgaag gtccatgtgc tagtcaaggt tttaagtccc
    28681 tttatcaaaa tttgcaagtt cgtgctgagg gtaatcagct atttattgaa ggatctgaag
    28741 cgattgataa ggaacatttt aagaagaatc atcttcctaa tttagccaaa caacttgaaa
    28801 agtttggttt tccaactttt aactgtcaag tcgagaagaa tgatgtcctg acccaagagc
    28861 aggaagaggc ctttcatgct gaaaatgagc agattgttca agctgccaat gaggaagcgc
    28921 tccgtgctat ggaacaactg gagcagatgg cacctcctcc agcggaagag aaaccagtct
    28981 ttgattttca agcgaaaaaa gctgcagcta aacccaagct ggataaggcg gagattactc
    29041 ctatgatcga agtgacgaca gaggaaaatc gtctggtatt tgaaggggtt gtttttgatg
    29101 tggagcaaaa agtgactaga acaggtcgtg ttttaatcaa ctttaaaatg acggactata
    29161 cttcaagttt ttctatgcaa aagtgggtta aaaacgagga agaggcccag aagtttgacc
    29221 tcatcaagaa gaattcttgg ctccgagttc gagggaatgt ggagatgaat aacttcacac
    29281 gcgatttgac tatgaacgta caggatctgc aggaagttgt tcactatgag cggaaggatt
    29341 tgatgccaga aggtgagcgt cgggttgagt ttcatgctca tactaacatg tcgactatgg
    29401 atgctttgcc agaggtcgaa gagattgttg caacagctgc taagtgggga cacaaggcgg
    29461 ttgctatcac agaccatggg aatgtccagt cctttccaca tggctataag gcggctaaga
    29521 aagcgggaat ccagctgatc tatgggatgg aagccaatat cgtggaggac cgtgtcccta
    29581 tcgtctataa cgaagtggag atggacttat cagaagcaat ctacgtggtc tttgacgtgg
    29641 aaacgacggg actttcagct atctataatg acttgattca ggttgcggcc tctaagatgt
    29701 acaaggggaa tgttattgct gaatttgatg aatttatcaa tcctgggcat cccttgtcag
    29761 cttttactac agagttaact ggaattacag atgatcatgt caaaaatgcc aaaccactag
    29821 aacaagtttt gcaagaattc caagaatttt gcaaggatac ggtcctagtt gcccacaatg
    29881 ctacctttga cgttggcttt atgaatgcta attatgagcg gcatgatctt ccaaagatta
    29941 gtcagccagt tattgatacg ctggagtttg ctagaaacct ctatcctgag tataaacgcc
    30001 atggtttggg gcctttgacc aagcgttttg gtgtggcctt ggaacatcac cacatggcca
    30061 actacgatgc ggaagcgact ggtcgtctgc ttttcatctt tatcaaagag gtagcagaaa
    30121 aacatggtgt gaccgattta gctagactca acattgatct aatcagtcca gattcttaca
    30181 aaaaagctcg gatcaagcat gcgaccatct atgtcaagaa tcaggtaggt ctaaaaaata
    30241 tctttaagct ggtttccttg tctaatacca agtattttga aggagtgcca cggattccga
    30301 gaacggttct agatgcccat cgagagggct tgattttagg ttcagcctgt tcagagggtg
    30361 aagtttttga cgtggtcgtt tctcaaggtg tggatgcggc ggttgaggtg gccaagtatt
    30421 atgactttat cgaggtcatg ccaccggcta tctatgcgcc cttgattgcc aaagagcagg
    30481 tcaaggatat ggaggaactc cagaccatta tcaagagttt gatagaggtt ggagaccgcc
    30541 ttggcaagcc tgttttggct acgggaaatg ttcactatat cgaaccggaa gaagagattt
    30601 atcgtgaaat tatcgtccgt agtttgggac agggtgcgat gattaaccga actatcggtc
    30661 atggtgaaca tgcccaacca gcaccacttc caaaggctca ttttcgaacg actaatgaga
    30721 tgttggatga atttgccttt ttgggagagg aactggctcg taaactggtt attgaaaaca
    30781 ccaatgcctt ggcagaaata tttgaacccg ttgaagtcgt taagggtgac ttgtatacgc
    30841 ctttcatcga caaggctgaa gaaacagttg ctgagttgac ctataagaaa gcttttgaga
    30901 tttatggaaa tccgctgcca gatattgttg atttgcggat tgaaaaagaa ttaacatcca
    30961 tactggggaa tggatttgct gtgatttatc tggcatcgca gatgctggtg caacgttcta
    31021 atgaacgggg ttatttggtt ggttctcgtg ggtctgtcgg atctagtttc gttgcgacca
    31081 tgattgggat tacggaggtc aatcctctct ctcctcacta tgtctgtggt cagtgtcagt
    31141 acagtgagtt tatcacagat ggttcgtacg gttcaggatt tgatatgccc cataaggact
    31201 gtccaaactg tggtcacaaa ctcagtaaaa acggacagga tattccgttt gagaccttcc
    31261 ttggttttga tggggataag gttcctgata ttgacttgaa cttctcggga gaagatcagc
    31321 ctagcgccca cttggatgtg cgtgatatct ttggtgaaga atatgccttc cgtgcgggaa
    31381 cagttggtac ggtagctgcc aagactgcct atggatttgt caaaggttac gagcgagatt
    31441 atggcaagtt ttatcgtgat gcagaagtag aacgcctcgc tcaaggagcg gcgggtgtca
    31501 agcggacaac aggccaacac ccggggggaa tcgttgttat tccgaactac atggatgtct
    31561 acgattttac gcctgtccag tatccagcag atgatgtcac ggctgaatgg cagaccactc
    31621 actttaactt ccacgatatc gatgagaacg tcctcaaact cgatgtactg ggacatgatg
    31681 atccgactat gattcgaaaa cttcaggatt tgtctggtat tgaccctaat aaaattccta
    31741 tggatgacga aggcgtgatg gcactctttt ctgggactga tgtgctaggg gtaacacctg
    31801 aacaaattgg aacgcctacg ggtatgttgg ggattccaga gtttggaaca aatttcgtac
    31861 gtggaatggt agacgaaacc catccgacaa cctttgcgga attgcttcag ctgtctggtc
    31921 tgtcccacgg tactgatgtt tggttgggga atgctcagga tctgattaag caaggaatag
    31981 tggacctatc gactgttatc ggttgtcggg acgacatcat ggtttacctc atgcatgcgg
    32041 gtctggaacc taagatggcc tttaccatta tggaacgggt acgtaagggt ttgtggctaa
    32101 agatttcaga agaggagaga aatggctata tcgaagcaat gaaggctaat aaggtgccag
    32161 agtggtatat cgaatcctgt gggaaaatta agtacatgtt ccctaaggcc catgcggcag
    32221 cctacgttat gatggccttg cgtgtagctt acttcaaggt tcaccatcct atttattact
    32281 actgtgctta cttctccatt cgtgctaagg cttttgatat caagaccatg ggtgcgggct
    32341 tggaggtcat caagcgcaga atggaagaaa tctctgaaaa acggaagaac aatgaagcct
    32401 ctaatgtgga aatcgatctc tatacaactc ttgagattgt caatgagatg tgggaacgag
    32461 gtttcaagtt tggtaaatta gatctctact gtagtcaggc gacagagttc ctcatcgacg
    32521 gggataccct tatcccacca tttgtagcaa tggatggtct gggagagaac gttgccaagc
    32581 aactggtgcg ggcgcgtgaa gagggagaat tcctctctaa aacagaacta cgcaagcgtg
    32641 gtggactctc atcaaccttg gttgaaaaga tggatgagat gggtattctt ggaaatatgc
    32701 cagaggataa ccagttgagt ttgtttgatg agttgtttta aaaaattgct taataatcta
    32761 ttaaaagagg ctaacgtata tccaatagat ttacattagc tttctttttt gttaaaatag
    32821 tctatggaaa gagggtgaga gtatgtcaaa gatgagtata agcatccgtc tggatagtga
    32881 ggttaaggag caggcccaac aggtgtttag taatctggga atggatatga caacagctat
    32941 taatattttc cttcgtcagg caattcaata tcagggatta ccttttgatg ttagactaga
    33001 cgaaaatcgg aagttgctcc aagcgttaac ggatttagac caaaatcgta atatgagcca
    33061 gtcttttgaa tcagtctcag atttgatgga ggacttacgt gcttaagatt cgttatcata
    33121 aacagtttta aaaagatttt aagttggcta tgaagcgtgg tttgaaggca gaattattag
    33181 aagaagtttt gaattttctg gttcaagaaa aagaacatcc tgccagatat cgtgatcatt
    33241 cattgacggc atccaagcat tttcaaggag ttcgtgaatg ctatacccag ccagattggc
    33301 ttttggttta taaagtagac aagtcggaat tgattttaaa tttgctgagg acaggcagtc
    33361 acagtgattt attttaatct attttaaggg ggttctcatg aaactaagaa tatttgcgga
    33421 agataagccg gctaagaagg tatttgaata tcaattagaa cttgctgatc gtacaattct
    33481 tctatcgaca gcactcttgt caggtgctat tgctttagca ggaatctttt ctgctttgaa
    33541 agaaaaataa aaatagaaaa gagaaaacag gatggtttta ccaaatttta aagaaaatct
    33601 agaaaaatat gcgaaattgt tggttgcgaa cggaattaac gtgcaacctg gtcacacttt
    33661 ggctctctct attgatgtgg agcaacgtga attggcacat ctaatcgtga aagaagctta
    33721 tgccttgggt gcgcatgagg tcatcgttca gtggacagat gatgtgatta accgtgagaa
    33781 attcctccat gccccgatgg agcgtttgga caatgtgcca gaatacaaga ttgctgagat
    33841 gaactatctc ttggagaaca aggctagccg tcttggagtt cgttcatctg atccaggtgc
    33901 cttgaacgga gtggacgctg acaagctttc agcttctgct aaagctatgg gacttgccat
    33961 gaagccaatg cgaatcgcaa ctcaatctaa caaggttagc tggactgtag cagccgctgc
    34021 tggacttgag tgggctaaga aagtcttccc aaatgctgcg agcgacgaag aagcagtcga
    34081 tctcctttgg gaccaaatct tcaaaacttg ccgtgtctac gaagcagatc ctgttaaggc
    34141 ctgggaagag catgcagcca ttctcaagag caaggccgat atgcttaata aggagcaatt
    34201 ttcagccctt cactacacag cgccaggaac agatttaaca cttggtttgc caaagaacca
    34261 cgtttgggaa tcagctggtg ctgtcaatgc acagggcgaa ggattcttgc caaatatgcc
    34321 gacagaagag gtcttcacag cgcctgactt ccgtcgtgca gatggttatg tcacttctac
    34381 aaaaccgctt agctacaacg gaaatatcat tgaaggcatt aaggtgacct ttaaggatgg
    34441 acaaatcgta gatatcactg ctgagaaggg tgatcaggtt atgaaagacc ttgtctttga
    34501 aaatgcgggt gcgcgtgcct tgggtgaatg tgccttggta ccagatccaa gtccaatttc
    34561 tcagtcaggc attaccttct ttaacaccct tttcgatgaa aatgcgtcaa accacttggc
    34621 tatcggtgca gcctatgcga ctagcgttgt tgatggagcg gagatgagcg aagaggagct
    34681 tgaagctgca gggcttaacc gttcagatgt tcacgtagac tttatgattg gttctaacca
    34741 aatggatatc gatggtattc gtgaggatgg aacgcgggta cctcttttcc gtaatgggaa
    34801 ttgggcaaat taaggagata atatgttagg aagtatgttc gttggtctcc tagtgggatt
    34861 tttagcaggt gctatgacca atcgtggaga gcgaatggga tgttttggaa aaatgtttct
    34921 cggttggatc ggagcctttc taggtcactt gctctttgga acttgggggc cagttttatc
    34981 aggaacagct attatcccag cgattttagg agccatgatt gttttagcta ttttttggag
    35041 acgaggaagt taatttccta aatctgatac tcaatgaaaa tcaaagagca aactaggaaa
    35101 ctagccgcag gttgctcaaa gcactgcttt gaggttggag atagaactga cgaagtcagc
    35161 tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat atatacggca
    35221 aggcgacgtt gacgcggttt gaagagattt ttgaagagta tgaaacgaaa aggaggttgg
    35281 tcattgtact agcctccttt tgatatgata taatagttct atgagattag ataaattttt
    35341 agttgcctgt gcggtgggaa gtcggactga ggtcaaaaac ttgctcaagg ctgggcgcgt
    35401 gactgtaaat ggtaaaaaag aaaaatcagc taaattgcag attgatgaaa aaatagatga
    35461 gattcgcttt gatgggcaag tgttggagta tgaagagttt gtctactaca tgatgaacaa
    35521 gcccaaagga gttatctcag cgactgagga tcccaagcac agaaccgttc tggacttgtt
    35581 ggatgacttg gcgcggagta aggaagtttt cccagtagga cgcttggata ttgacacgca
    35641 tggtcttttg ctcttgacca atgatggtca gctggctcat gttcttcttt cgcccaagcg
    35701 tcatgtggac aagacttatc tggcacaagt caagggaatc atgacccaag aagatgtgga
    35761 gacatttgct gagggtattc ctctcaaaga ctttacctgt caacccgcta tactggagct
    35821 tgtatccata gatacagaaa agaatcaaag ccaaatccgt gtgaccattg cagaagggaa
    35881 gtttcatcag atcaagcgta tggtgggcta ctgtggcaag gaagtggtgg acttgcaacg
    35941 attgactatg ggaactttag tattagatga gaacctagaa cgaggggaat ggcgtcgctt
    36001 gaccaaggaa gaattagaaa ttctccgcgc taatattatt taatttagtt taatactcaa
    36061 tgaaaatcaa agagcaaact aggaaactag ccgcaggctg tacttgagta cggcaaggcg
    36121 acgttgacgt ggtttgaaga gattttcgaa gagtataaat tcgaaaaagg tgagggacaa
    36181 tgtcctcgcc ttttatgttt tttagttgct tcctttgtga aaagagttat aatagactgt
    36241 agaataaaag gaggaatcta tgaacgcgat tcaagaatca tttactgata aactatttgc
    36301 caactatgaa gcaaatgtaa aataccaagc gattgaaaat gctgccagcc acaacggaat
    36361 ttttgcagct ctggaacgtc gccaaagcca tgtagacaac acacctgttt tctcattgga
    36421 tttaaccaag gacaaggtca ctaaccagaa agcgtctggt cgttgctgga tgtttgcggc
    36481 tctcaacacc ttccgccaca aactcatctc gcaatacaaa ttggagaact ttgaattgtc
    36541 acaagcccac actttcttct gggataagta tgagaaatca aactggttct tggagcaagt
    36601 cattgcgact tcagaccaag aattgactag ccgcaaggtt agcttcttac tccaaacacc
    36661 tcaacaagat ggtggtcaat gggatatggt cgtttccctc tttgaaaaat acggtgtcgt
    36721 gcctaagtca gtttatcctg agtctgtttc atctagcagc agtcgtgagc taaatgcgat
    36781 ccttaataaa ttgcttcgtc aagatgctca aatcttgcgt gacttgcttg tttctggtgc
    36841 agatcaagcg actgttcaag ctaagaaaga agacctcttg caagaaatct ttaactttct
    36901 tgctatgtca ttaggacttc caccacgcaa gtttgacttt gcttatcgcg ataaagataa
    36961 caactacaaa agtgaaaaag gaatcacacc acaagagttt tacaagaaat atgtcaatct
    37021 tcctttagaa gactacgttt ctgttatcaa tgctccaact gctgataaac cttacggaaa
    37081 atcttacaca gttgagatgt tggggaatgt ggttggtagc cgtgcagttc gctacatcaa
    37141 cgttccaatg gagcgcttga aagaattggc gattgcccaa atgcaagcag gtgagactgt
    37201 ttggtttggt tctgatgtcg gccagctcag caaccgtaag gctggcatcc ttgcgacaga
    37261 tgtttatgac tttgaatcaa gcatggacat taaacttact caagacaagg ctggacgttt
    37321 ggactatagt gaaagcttga tgacccacgc catggtcttg acaggtgttg acttggacga
    37381 aaatggtaaa tcaaccaagt ggaaggttga aaactcatgg ggagacaagg tcggtacaga
    37441 tggttacttt gttgcctcag acgcttggat ggacgaatac acataccaaa tcgttgttcg
    37501 taaggaattg ctgacagcag aagaacaagc tgcctatgga gcagaaccaa tcgtacttgc
    37561 accatgggat ccaatgggag ccttggctga ataaaagcat agaaaaaagg aatcagattt
    37621 tagaacctgg ttccttttta gttgcttgat tacatgatgt gaagaacatg tgccacaata
    37681 cccactgcga agagggcaag gataatagtg attggagata cttttttctt aagtaagtac
    37741 atgcaaagta aagtaaggag tagtcctgat aatccaggaa tcaacatatc caagttttgt
    37801 tggaaagtag taactttttc aggagtttga gacaatcctt gtcctacttg tgcgaatgct
    37861 tcttggatac ctttagaccc ttctggcaat ttatcccaat ggatataagc cttttcatct
    37921 agttgaactt tagaaacatc gaaagcaaat ttaatattta cccagcgttg aacaaggaca
    37981 gcaagaatga acatcccaag gatagaagct cctttagtga tatcttgaag gataccacca
    38041 gacatatctt tagtgatttc tgatccagcc ttgtatccaa tctcttgaac ataccacaag
    38101 aatgacatac gaatcaagtt ccatgcaaca aagaagagga gtggccccaa gatattgcca
    38161 gtaagggcaa gtgaagcacc gagagatcca aggattgggc gtactgtaaa ccagaatact
    38221 gggtcaccga taccagcaag aggtcccatc ataccgattt taaccccttg gatagcagcg
    38281 tcatcgattt ccacaccgtt agcacgttct tcttcaagcg caagagtaac ccccatgact
    38341 ggagcagcta cgtatggatg agtgttgaag aactcaaggt gacgttcaag agcagcgatt
    38401 tgatcttctt ttttagtata gagttttttg atagctggaa tgagtgtata agcccagccc
    38461 aagttttgca tccgttcaaa gttccaagac ccttgtaaga aggttgaacg ccaccaaact
    38521 tttttacgat ctgatttagt taattgaagt ttttcagtca tgatgttttc agtcctttct
    38581 tatcttagta gtcttctagg atatcgccga ttgggtcgtt agaagttgcg gctcctccgc
    38641 caccatttcc accagtttta gaaaggtgaa ggtagataag agcgatagca acaccgatag
    38701 caccgaatcc gattagagta atatctgaca cagcagcgag aacgaaacca agagcgaaga
    38761 atggccatac ttcacgagtt gccatcatgt tgataaccat ggcgtaacca acggcaacga
    38821 ccataccacc accgatagcc ataccatctt tgagccagtc tggcatggca ctaaggatac
    38881 tttgtacagt ttcagttggt accataagga gaagagctgc aggaagcgcg atacgaagtc
    38941 cttggaagag tagcgcaatg aaatgcgcac gctccacagc gccgaagtca ccttttttag
    39001 cggcagcatc tgcagtatga accaaaccaa ctgaaattgt acgaacaatc attgtcaaga
    39061 aaagtccagc tacggcaaga gggatagcaa ccgcttgggc aacaccgata ccagtcttgg
    39121 taaagtcacc accaagaacc atgataatgg cagcagcgac agaagcaagt gcagcatcag
    39181 gagcgatagc agcaccgata tttgaccaac caagggcaat catttgaagc gatccaccga
    39241 ggataatccc tgcttccaag tgacctgtta caagcccaat aagggtacag gctacaagtg
    39301 gttggtgaaa ttggaactgg tcgaggatgc cttcaagacc tgcaaagaag gctacaacga
    39361 ctactaaaac catagaaata atagacatgt ttaaaatcct ttcataaata atggcttatt
    39421 tgacattggc tttgttaatc aagtcaaaca aatctttttt agaatcattt ggtactttac
    39481 ggacatcaaa ttcaacaccc aagtcacgca ttttttcaaa tgtagcaaca tcttctttgt
    39541 ccatagacaa aacggtattg accaatgttt tacctgttga gtgagccata gaaccaacgt
    39601 taagagtctt gattggcacg ccgccttcga tggcacgaag ggcatcttga ggtgtttcaa
    39661 acaagataag ggcatgtgtt tctccaaaac gtgggtcttt tgaaatctca atcagttttt
    39721 gaattggaac cacgttagcc ttgacattac ctggagctgc ttgtttaatc aattctttac
    39781 gaaggtcgtc tttagccacg ttatctgaag caacgatgat acgatttgct tttgaatctg
    39841 gagtccaagc agttgcaacc tgaccgtgaa gtagacgtgt gtcaagacgg gcaagattga
    39901 ttttcaattt accgtctccg ataacagttc cttctgggat agcagtttgg gcaactggag
    39961 cagctgcagc gcttgcaact tcttcaactg gatttagctc ttctggaaga gctttgatgc
    40021 catctttggc ttctttaatg atattagcag cgactttttc tacacctgca gcagcgtcca
    40081 tgaggcgctc tgtgtaggct tgaatcaaca tcggtaagtt aagtcctgtg atgatggcaa
    40141 acttacgctc aggattttct cccatcacgc gactagcttg gttaaatgga gaaccactcc
    40201 aaaggtcagc caaaactaga acctcatctt ctgcgtcaaa tgcagcaaca gcgttattaa
    40261 acttagcgta tagatcatca ggaccttcat ttggcataaa ggtcacaact tgaacctttt
    40321 cttgttcacc aaagatcata gatcctgact gatgaatacc cgcagcaaat tcgccgtggc
    40381 tcgcaataat gattccgata ctcattattg tcattcctcc ttttttgttt tagttttcat
    40441 ttaagaaaac tttaagactg tttaagtata aaccgttttc ataaaaaaag caactattta
    40501 tcataaaaaa ttaaaaaaat ttttattttt gtatgttgat atgttgagtt tttgaggagt
    40561 aatcttgaat tcttatttaa aaatttaata taaaaaagtt ggaagaagtt tccaactttt
    40621 aaaataggtt tctattagat tagtgggtga agtcgagtac catacgtcct tggatttggc
    40681 ctttttccat ttcgtcgaaa atggcaacag catcttctac tggacgtttt tgaacaactg
    40741 ggactaccag accttctgca ccaaattgga aggcttcttc taagtcttta cgagttccga
    40801 caagagaacc gatgacttgg attccatcga ggactgtttt aacgatgctg agttccatca
    40861 tttcagaagg aagaccaaca gcgacgacgc gaccaccagc acgaacggag tcaacagcct
    40921 ggttgaaggc aactttagac acagcagtta cgacagctga atgagctcct ccatcagttt
    40981 tttctttgat gagtccagct acatcttcaa cttcgaggcc gttaatcaca atgtcagcgc
    41041 ctacttcttt tgcaagggca agtttgtcat tgttgatatc gactgcgata acatgagcat
    41101 tgaatacttt tttagcgtat tgaacagcga ggttaccaag tccaccagca ccgtaaagaa
    41161 caacccattg gcctggttca acttttgctt ctttgatagc tttataggtt gttactccag
    41221 cacatgtgat agaagaagct tgggctggat caagtccgtc aggaactttg acagcatagt
    41281 cagcagttac gatacattgt tcagccatac caccgtctac tgagtagcca gcatttttca
    41341 ctgtacggca aagggtttcg cgaccagttg tacagtattc gcaagtgcca catccttcaa
    41401 agaaccaagc aacgctgacg cggtcaccga ctttaaggct tttcacatct ggagcaatct
    41461 ctttaacgat accgatacct tcgtgcccaa gaacacgtcc tgggacttga ccaaagtcac
    41521 catgagcaac gtggaggtcg gtgtggcaaa caccacagta ttcaacttct acaagtgctt
    41581 ccccagtttc aagtggacgg agtacttttt cttcaatagc aacaccagtg ctttctggat
    41641 ttacaacaac agctttcata gctatcctcc ttgatattga ccgagaacag ggacaacggg
    41701 actggattga ttttttgtca acagagtcga gtgtgacgag ctctcttgta tttatatgtg
    41761 aagtatatca caaaagaaag ccttttccaa ggttttggag acaaaaagta gaacaatcga
    41821 ttaactggtt gatgagactg tgaaaagagc acaaagacca gcttgcaagc tggtctttgt
    41881 gctcttcgaa aatctcttca aaccacgtca gcttcatcta caacctcaaa gcagtgcttt
    41941 gagcaaccta cggctagctt cctagtttgc tctttgattc tcattgagta tcagtatagg
    42001 ttataagaat aagtcttgta gggttttggc aaccccatct tggtcgttgg taagggaaat
    42061 ttgctcatct gcataaggga gtagctctgg attggcattt ttcatggcat aacccttccc
    42121 agcaaaagcg agcatttcgg tatcattgtg ttcatctcca aaggcaatca aatctttttt
    42181 gtcacgattc attatcttga gcaagtagtc caaagcaaag gccttgttga caccttttgg
    42241 ggtacattca aggatattga gcggacctcc ccaggtattg atagaaagtt gatgctggta
    42301 gaaggcgttc atttcttttg ccaaggcata tttgtcactg gctctggtct gcaagaggat
    42361 acagttaggg tccttggtca ccaattcagg ctggaattga tcttcaggct ggaaagcttc
    42421 tacaccaaat agtttgggat tggcaatttc ttcattggga tttgtaatgt agaatttttt
    42481 acgatattct ccagcgataa aatcggcttg aatgtcctct gaacgttgaa ccatatctag
    42541 cagatatttt ttgtctacag tcaaacactt ttcaaaatcc caaacttggt ctggtaaatg
    42601 agtaagggat ccgttgaagt taatcatagg agtgtctaag cccagttcac ggtaaaaatc
    42661 ttttgacata cggtaagggc gacctgtcgt aataataacc tgatggcctt tttcagcaac
    42721 ttttttgatg gttcttttgg taaagtcaga aatttgactg tctgagttga gcagggttcc
    42781 atccaggtca actgcaataa tttttttcgt catatggacc tttctagtgt gttttcagat
    42841 aagatgtctt ctattataac agaaagcagg cagaaaagca gattccaaac aaaaaatgaa
    42901 attggattaa tttcttaaac aaatcaaaca aagacattga aaaagtgaat gataaatgat
    42961 ataattctat tattgttcgt aaaaattaaa aggagattga tgatggacaa attatttaaa
    43021 ctaaaagaga acggtacaga cgttcgtaca gaggttctcg ctggtttaac aactttcttt
    43081 gcaatgagct atattctctt tgtaaaccca caaatacttt cacaaacagg aatgcctgct
    43141 cagggcgtct tcctagcgac gattattggt gcagtagcgg gtaccttgat gatggctttt
    43201 tatgctaact taccttatgc ccaagcgcca ggtatgggac tcaatgcctt ctttaccttt
    43261 acagttgtat tcgggcttgg ttattcttgg caagaagccc tagctatggt cttcatctgt
    43321 gggattattt cattgattat taccttgaca aatgttcgta aaatgatcat tgaatcgatt
    43381 cccaatgctc ttcgctcagc tatttcagct ggtatcggtg tcttccttgc ctatgtaggg
    43441 attaagaatg ctggactttt gaaattcacg attgatccag gcaactatac tgttgtagga
    43501 gaaggggctg acaaagctca agcaacgatt gcagcaaact cttcagcagt tccaggattg
    43561 gtcagcttta ataatccagc tgttttagtg gctcttgcag gacttgccat tactatcttc
    43621 tttgtcatca aagggattaa agggggaatt attctctcta tcttgacaac aactgttctt
    43681 gctattgcag ttggtttggt tgatttgtct agtatcgatt ttgctaataa ccatgttggt
    43741 gcagcttttg aagatttgaa gacaatcttt ggtgcagctc ttggttcaga aggtttggga
    43801 gctttggttt cagatacagc tcgcttgcct gaaactctga tggccattct tgccttctca
    43861 ttgacagata tttttgacac aattggtacc ttgatcggta caggtgaaaa agttggtatt
    43921 gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg ataaggctct ttactctgat
    43981 ttgattggaa cgacagtcgg tgccattgca ggtacttcaa acgtaacgac ttatgttgag
    44041 tctgctgctg gtatcggtgc aggtggacgt actggtttga cagccttggt tgtagctatc
    44101 tgttttgcga tttcaagctt ctttagccca cttctagcga tcgtaccaac agcggctaca
    44161 gctccaatct tgattatcgt tgggattatg atgcttggta gcttgaaaaa tatccattgg
    44221 gatgatatgt ctgaagcagt tcctgccttc ttcacatcta tctttatggg attcagctac
    44281 tctatcactc aagggattgc agttggtttc ttgacttaca ctttgactaa gcttgtcaaa
    44341 ggtcaagtta aagatgttca tgccatgatt tggattttgg atgccttgtt tatccttaac
    44401 tacatcagca tggccttata atagaatgac ccagggggat ttcccccctt ttttaataca
    44461 aaaggagata ggtgatgaaa gagaaaaata tgtggaaaga attgttgaat cgtgcaggct
    44521 ggattttggt ctttttactt gccgtccttt tatatcaggt tcccctagtg gttacctcta
    44581 ttttgacttt aaaagaagta gccctgctac agtcagggct gatagttgct ggcctttcaa
    44641 ttgtggttct ggctctattt attatgggag ctcgtaaaac caagttagct agttttaatt
    44701 tttctttttt tagagctaaa gatttggcac gtttgggctt gagttatcta gttattgtcg
    44761 ggtcaaatat acttggttct atcttgttgc aactgtcaaa tgagacgaca actgctaacc
    44821 agtctcagat taatgatatg gttcaaaata gttcgttgat ttccagtttc ttcttgctag
    44881 ccttgcttgc tccgatttgt gaggaaatct tgtgtcgtgg gattattcct aaaaagattt
    44941 tccgaggcaa ggagaacttg ggatttgtag tcggtacgat tgtgtttgct ttattgcatc
    45001 aaccaagtaa tttaccttct ttattgattt atggaggtat gtcgacagtt ctatcttgga
    45061 cagcctacaa gacccaacgt ttggaaatgt cgatcttgct tcacatgatt gttaatggga
    45121 ttgctttctg tttgttggct cttgtggtga ttatgagtcg gacattagga atttctgtgt
    45181 aaaagttttt atgtaggaac cgacctcttt ctactaggga aagatgaatg caatcgtgtc
    45241 catctttttc tttttatggt aaaatagaaa aataatatga tgaaaatcct tgagggagtg
    45301 accgatatgt caagtaaagc caatcatgca aagacagtta tttgcggaat tatcaatgta
    45361 accccagact ccttttcgga cggtggtcaa ttttttgctc ttgagcaggc actccagcag
    45421 gctcgtaaat tgatagcaga aggagccagt atgctcgata tcggcggaga atcgactcgg
    45481 ccgggcagta gctatgttga gatagaagag gaaatccagc gtgttgttcc agtgatcaaa
    45541 gcgattcgca aggaaagtga tgtcctcatc tctattgata cttggaagag tcaagtagca
    45601 gaggctgctt tggctgctgg tgccgatcta gtcaatgata tcactggtct tatgggtgat
    45661 gagaaaatgc ctcatgtggt agctgaagcg agagcgcaag tggtcatcat gtttaatcca
    45721 gttatggcgc gacctcagca ccctagctcg ctcatcttcc ctcattttgg ttttggtcaa
    45781 gcttttacag aggaagagtt agctgacttt gaaacattgc caatcgaaga attgatggag
    45841 gctttctttg aacgagcact agcgagagcg gcagaagctg gtattgcacc agaaaatatc
    45901 ctgttggatc caggaattgg ctttggtctg accaagaaag aaaatctgct tcttttacgg
    45961 gacctggata aactacatca gaagggctat ccaatctttc tcggagtgtc gcgcaagcga
    46021 tttgtcatca atatcctaga ggagaatggt tttgaagtca atcctgagac agagcttggt
    46081 ttccgcaatc gggacacggc ttcggctcat gtaactagta tcgctgcgag acagtgtgta
    46141 gaagtggtgc gcgtgcatga cgtagctagt cacaggatgg cagttgaaat tgcctctgcc
    46201 attcgtctgg ctgatgaagc ggaaaattta gatttaaaac aatataaata agatgaaaga
    46261 aattgaaaac aatcagtgga ttgctaacta ccggacggat caaccgcatt ttggcttgga
    46321 acgaatggtg gaactgttag ctttgcgtgg caatccccat ctcaaactca aggtcctcca
    46381 tatcggaggg actaacggca agggctcgac tattgctttt ttgaaaaaga tgctagaaaa
    46441 gctagggctg agagttggcg tgtttagctc gccctatctc attcattaca cagaccagat
    46501 tagcatcaat ggggaatcga tctcagaagc gaggctagaa gctctcatgg cagactatca
    46561 gtctttgctg gagggagaag cggtcgccaa tttacagggc acaaccgagt ttgagattat
    46621 cacagccctg gcctatgact actttgcctc agagcaagta gatgtggcca tcatggaagt
    46681 tggcatgggt ggacttttgg atagtaccaa tgtctgtcag cccattttga caggaattac
    46741 aactattggc ttggatcatg tggccctact tggtgacacc ttggaggcca tagcagagca
    46801 gaaggcaggt attatcaaac aagggatgcc cttggtaaca gggcgtattg ctccagaagc
    46861 cttggctgtg attgaccgca ttgcggaagg gaaagatgcg ccgagacttg cctacgggac
    46921 agattatcag gttcgtcatc aagaaagtgt ggtgacaggg gaagtctttg actatacaag
    46981 tgctgtcaga caaggtcgct tccagactag cctgcttggt ttgtaccaaa tagagaatgc
    47041 tgggatggcc atagctttac ttgatacttt ttgtcaagaa gatggtcgag agctagcaag
    47101 caatgacttt cttggtcaag ccttggaaga aacaagttgg ccagggcgtt tggaaatcgt
    47161 gtcaagagat cccttgatga ttttggatgg agcccacaat ccccatgcta tcaaggcctt
    47221 gttggtaacc ttgcaagaac gttttgcgga ttatcataag gaaatcctct tcacttgtat
    47281 caaaaccaag gccttggagg atatgttgga cttgctggga gccatgccag ataccgagct
    47341 tactctaaca cattttgcgg atagtcgggc gacggatgaa agcgtgctga aagaggcagc
    47401 taagtctaga aatctcagct accaagattg gcatgatttt ctagagcaga atgtgacaga
    47461 taaaaaagaa gagaaacaaa cagttaggat tgtcacaggt tccttgtatt tcttgagcca
    47521 agtgagggcc tatctgatgg agaggaagaa cgagaatgga tacacaaaag attgaagcag
    47581 ctgtgaaaat gattatcgag gctgtaggag aggacgctaa tcgcgagggc ttgcaggaaa
    47641 cacctgctcg tgtggcccgt atgtatcaag agattttttc aggtcttggt caaacagcag
    47701 aggaacattt gtcaaaatcc tttgaaatta ttgacgataa tatggtggta gaaaaggata
    47761 tctttttcca taccatgtgt gaacaccact tcttgccatt ttatggtaga gcgcacattg
    47821 cctacattcc agatggtcgt gtggcaggct tgtctaagct agcccgtacg gttgaagttt
    47881 attcgaaaaa accacaaatt caagaacgtt tgaatattga agtggccgat gccttgatgg
    47941 actatctagg tgctaaagga gcctttgttg tcattgaggc ggaacatatg tgtatgagta
    48001 tgcgtggtgt tagaaaacca ggcactgcaa ccttgacgac agtagctcgt ggtctatttg
    48061 aaacagataa ggacctccgc gaccaagctt atcgtttaat ggggctataa aaagaatccg
    48121 cttcaagcgg atttttctag aaaggaatca ttatggatca actgcagatt aaggatttgg
    48181 aaatgtttgc ctatcatggt ctttttccta gtgagaaaga attggggcag aaatttgtcg
    48241 tttcagccat cctatcctat gatatgacca aggcagctac agacttggat ttaacagcct
    48301 ctgtccatta cggagaattg tgtcagcagt ggacgacttg gtttcaggaa acgagtgaag
    48361 atttgattga aacggtagcc tataaactgg tggaacgtac ctttgagtct tatcctcttg
    48421 tccaagaaat gaagttggaa ctgaaaaaac cttgggcacc ggtgcatttg tcactagata
    48481 cttgctcggt aaccattcat cgccgcaagc aacgagcctt tatcgcccta ggaagcaata
    48541 tgggagataa acaagcaaac ttgaagcaag ccattgacaa actgcgagct cgtggcatcc
    48601 atattctcaa agagtccagt gtcttagcga cggagccttg gggtggtgtt gagcaggata
    48661 gctttaccaa tcaagtggtt gaagtagaaa catggttgcc tgcccaagtg ctattagaaa
    48721 ccttgttagc cattgagtca gagctgggac gggtgagaga agtgcattgg ggccctcgtt
    48781 tgattgattt ggacttgctc tttgtggagg accagatcct ttatacagac gacctcatat
    48841 tgcctcatcc ttacatagcg gaacgccttt ttgtccttga gtccttacag gaaattgcgc
    48901 ctcattttat ccatccgata ttaaaacaac cgatccgcaa cttgtatgat gctttgaaaa
    48961 aatagaaaaa ctctagtttt cagttacttg caactgaagg ctagagtttt taaaataggt
    49021 cattttcttc tgggaggagg atagtttctc taccgtccat gtctaaaacc agtactcttg
    49081 ggggataacg agggtcgaaa ggatggttaa agtcaaaatc aatggctgta gggaggtgtt
    49141 gacttgaaaa gtggaaggta atctttcctt ggttattaag caattgaaac tcgaattctt
    49201 cttccaattc aaagacattt tttaagaaat gatcgatgat ataccaaaaa gagtcaatga
    49261 tgtcatcggg caagctggta acaatgccaa aactagcaga ccgcatgtgg gtattggtaa
    49321 aagccatatc tctgtcccct ttcttttccc ttatcataca gcaaatagga ttaaaaatca
    49381 agaaaaggtg attttttgaa aaggatttta actacaggga aaaagaagga aaaaaatccc
    49441 aaaaatctac cgaagttaat aggtaaattc ccaaattaac ttgattatat aactttcagt
    49501 tactttgaga agttaccgaa aaatattttt catatctatt gacttttagg ggtgaaattt
    49561 ggtatgatag taggcggtat tgtttacccc atttgaaagg ccccggaacc ttccaaatac
    49621 ttttcgatgg gaaggaacac ccatcaccgt aaacaaaaat cgaactatat ataggagaaa
    49681 tcatgaacaa aacaacattt atggctaaac caggccaagt tgaacgtaaa tggtacgtag
    49741 ttgacgcaac tgatgtacca cttggacgtc tttctgcagt agttgctagc gtacttcgcg
    49801 gaaaaaacaa accaacattt acaccacaca ctgatacagg tgacttcgtg attgttatca
    49861 atgctgaaaa agttaaattg actggtaaaa aagcaactga taaaatctac tacactcact
    49921 caaaccaccc aggtggattg aaacaaatct ctgcaggtga acttcgttct aaaaatgcag
    49981 tacgtttgat tgagaaatca gttaaaggta tgcttccaca caatacactt ggacgcgctc
    50041 aaggtatgaa gttgaaagta tttgttggag ctgagcacac tcacgctgca caacaaccag
    50101 aagttcttga catttcagga cttatctaag gaaaggaaca ataaagtatg tcacaagcac
    50161 aatatgcagg tactggacgt cgtaaaaacg ctgttgcacg cgttcgcctt gttccaggaa
    50221 ctggtaaaat cactgttaac aaaaaagatg ttgaagagta catcccacac gctgaccttc
    50281 gtcttgtcat caaccaacca ttcgcagtta cttcaactgt aggttcatac gacgttttcg
    50341 ttaacgttgt aggtggtgga tacgctggtc aatcaggagc tatccgtcat ggtatcgctc
    50401 gtgcccttct tcaagtagac ccagacttcc gcgattcatt gaaacgcgca ggacttctta
    50461 cacgtgactc acgtaaagtt gaacgtaaga aaccaggtct taagaaagct cgtaaagcat
    50521 cacaatttag taaacgttaa ttcgaaagaa ttactatact tatacagagc acctttcggg
    50581 gtgttctttt tttatacttt cttactaaat tggtgcaatt gacacagttg ttgcgacttt
    50641 agtcgcttac aaatgtggct gcaacctgac aaggtcagtt acctcaaaac gttaatcaat
    50701 acgattatat caatgtttca aagcactcaa aggtttgccc tatgggtgct tttttctata
    50761 ctttctaaaa aagttttccc taaaatttgc cctaaaatta ccctacttgt ttttaagatg
    50821 ttggtaggca acttgtccag cagataatgg aactatgttt gaagcattaa cataagtttt
    50881 agttgtaatt gtatcactat gagttaatac ttcagaaatg gcttctaagc tcattcctgc
    50941 ctttttagca agtgtcgctc ctgtatgtcg taatttatga ggtgtagcgt gttttaactt
    51001 tgggtgtcgt ctttttacag agttcatttt gttattgaga taatcaacgt gtagagggct
    51061 atttacatta cctttcgtat ctatataggt aaagactagt tgatcggatg tttgcattat
    51121 accaaatttc gctaactcat atttctgctg ttttttccat tctgaaagaa gtgatacaag
    51181 gtaactagga attgaaaaaa tcgttttctt atttcctttt gttgacttta cattcttata
    51241 tttgtcaagt gcatgcctta agccaatttg agcgtttgcc aagtctatgt ttttccaatg
    51301 tagagcatag gattctgatt ttctatcgct caaaataaag gttgtaaaga ataggacata
    51361 atcttttagt gataatttgt cgttctccaa atcttctcta aaagcatcaa accaatcttg
    51421 taattcttca ctagatagat acaaatcttc ctcatcctta gcttcttcta gctttatttt
    51481 tttacttgct ttaatacgtt ttatgctttt tgataatcta tttgattcaa tgtattctaa
    51541 ttcttcagcc caatcgaaaa ttgagtttac atagcttcga ataaccttga aattagcata
    51601 ttcttcagct ttagcagtca ttaagtttag tacgatttgc ttattctgat tcagaaaatt
    51661 gattgaataa ttaccgaaca ttggtaagat gtgcttcctg aaaactattt cagtattatc
    51721 aatagtaact tgtgttgggg gtttagttgt tgaagttgtt tgaccagctt tgtatgaatc
    51781 ccaccaaata ttattaaaga actcagagaa aagaatatca ctagttttaa ggagtgggat
    51841 atcctctcca ttttcaagtt gatgtatctt tgttagaatt tctaattcag cttctttagc
    51901 ctcctttctt gttttatagc gtttaacaaa gtgatttcct taaagatata aatactgatt
    51961 tcccgcttcc tgtacctcca gcaactagaa tatgaggaca cttgatagga ttataattca
    52021 caccgtatcc taaatctata ttaaggttat ctatctcttg cttctggttg tgagattgaa
    52081 gaactaacct gtcaggtttc ttgtaataga aatggtattc cataaaacta ggacgaataa
    52141 ttttgtattc tagttccagt tcgagtactc cagcaagaac atcatcaagt gattgtaccc
    52201 ttttactaaa ttcatcacca gtaatcagag ctttgataaa gatatgcccc ttttgtttgt
    52261 ctaactcgta ttgtaagatt gcgctcctag agattttttc atatcctgag ctatctttat
    52321 gtgttg
//
LOCUS       DAVHSI010000013        52041 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.013, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000013 DAVHSI010000000
VERSION     DAVHSI010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.013"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(74..1498)
                     /locus_tag="VVR21_000838"
     CDS             complement(74..1498)
                     /locus_tag="VVR21_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU6054748.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALSPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2043..4322)
                     /gene="pulA"
                     /locus_tag="VVR21_000839"
     CDS             complement(2043..4322)
                     /gene="pulA"
                     /locus_tag="VVR21_000839"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU6054749.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFSHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4434..6392)
                     /gene="ligA"
                     /locus_tag="VVR21_000840"
     CDS             complement(4434..6392)
                     /gene="ligA"
                     /locus_tag="VVR21_000840"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU6054750.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLTEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6485..7663)
                     /locus_tag="VVR21_000841"
     CDS             complement(6485..7663)
                     /locus_tag="VVR21_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6054751.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7743..8606)
                     /locus_tag="VVR21_000842"
     CDS             complement(7743..8606)
                     /locus_tag="VVR21_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU6054752.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8609..10510)
                     /locus_tag="VVR21_000843"
     CDS             complement(8609..10510)
                     /locus_tag="VVR21_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6054753.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(10936..11211)
                     /locus_tag="VVR21_000844"
     CDS             complement(10936..11211)
                     /locus_tag="VVR21_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU6054754.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(11318..12157)
                     /locus_tag="VVR21_000845"
     CDS             complement(11318..12157)
                     /locus_tag="VVR21_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6054755.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGHILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            12299..13147
                     /locus_tag="VVR21_000846"
     CDS             12299..13147
                     /locus_tag="VVR21_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU6054756.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(13240..14157)
                     /locus_tag="VVR21_000847"
     CDS             complement(13240..14157)
                     /locus_tag="VVR21_000847"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU6054757.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            14595..14800
                     /locus_tag="VVR21_000848"
                     /pseudo
     CDS             14595..14800
                     /locus_tag="VVR21_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(15005..15298)
                     /gene="rpmA"
                     /locus_tag="VVR21_000849"
     CDS             complement(15005..15298)
                     /gene="rpmA"
                     /locus_tag="VVR21_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU6054758.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(15315..15659)
                     /locus_tag="VVR21_000850"
     CDS             complement(15315..15659)
                     /locus_tag="VVR21_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU6054759.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(15675..15989)
                     /gene="rplU"
                     /locus_tag="VVR21_000851"
     CDS             complement(15675..15989)
                     /gene="rplU"
                     /locus_tag="VVR21_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU6054760.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(16025..16112)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(16177..16875)
                     /locus_tag="VVR21_000852"
     CDS             complement(16177..16875)
                     /locus_tag="VVR21_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU6054761.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            17277..17576
                     /locus_tag="VVR21_000853"
     CDS             17277..17576
                     /locus_tag="VVR21_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU6054762.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(17917..18891)
                     /gene="pta"
                     /locus_tag="VVR21_000854"
     CDS             complement(17917..18891)
                     /gene="pta"
                     /locus_tag="VVR21_000854"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU6054763.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKVKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(18935..19831)
                     /locus_tag="VVR21_000855"
     CDS             complement(18935..19831)
                     /locus_tag="VVR21_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6054764.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(19828..20646)
                     /locus_tag="VVR21_000856"
     CDS             complement(19828..20646)
                     /locus_tag="VVR21_000856"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU6054765.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(20630..21301)
                     /locus_tag="VVR21_000857"
     CDS             complement(20630..21301)
                     /locus_tag="VVR21_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU6054766.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            21429..21998
                     /locus_tag="VVR21_000858"
     CDS             21429..21998
                     /locus_tag="VVR21_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU6054767.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            22108..23067
                     /locus_tag="VVR21_000859"
     CDS             22108..23067
                     /locus_tag="VVR21_000859"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU6054768.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            23077..24192
                     /locus_tag="VVR21_000860"
     CDS             23077..24192
                     /locus_tag="VVR21_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6054769.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            24197..24544
                     /locus_tag="VVR21_000861"
     CDS             24197..24544
                     /locus_tag="VVR21_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU6054770.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            24552..24767
                     /locus_tag="VVR21_000862"
     CDS             24552..24767
                     /locus_tag="VVR21_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6054771.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            24850..25491
                     /locus_tag="VVR21_000863"
     CDS             24850..25491
                     /locus_tag="VVR21_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU6054772.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            25509..26198
                     /locus_tag="VVR21_000864"
     CDS             25509..26198
                     /locus_tag="VVR21_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU6054773.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(26195..26875)
                     /gene="radC"
                     /locus_tag="VVR21_000865"
     CDS             complement(26195..26875)
                     /gene="radC"
                     /locus_tag="VVR21_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU6054774.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(26918..29209)
                     /gene="pcrA"
                     /locus_tag="VVR21_000866"
     CDS             complement(26918..29209)
                     /gene="pcrA"
                     /locus_tag="VVR21_000866"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU6054775.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYIDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTKEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(29392..30116)
                     /locus_tag="VVR21_000867"
                     /pseudo
     CDS             complement(29392..30116)
                     /locus_tag="VVR21_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(30496..31356)
                     /locus_tag="VVR21_000868"
     CDS             complement(30496..31356)
                     /locus_tag="VVR21_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU6054776.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(31372..32649)
                     /locus_tag="VVR21_000869"
     CDS             complement(31372..32649)
                     /locus_tag="VVR21_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6054777.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATTINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(32642..33193)
                     /locus_tag="VVR21_000870"
     CDS             complement(32642..33193)
                     /locus_tag="VVR21_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054778.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWAQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(33209..34468)
                     /locus_tag="VVR21_000871"
     CDS             complement(33209..34468)
                     /locus_tag="VVR21_000871"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6054779.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(35555..35713)
                     /locus_tag="VVR21_000872"
     CDS             complement(35555..35713)
                     /locus_tag="VVR21_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054780.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(35723..37033)
                     /gene="obgE"
                     /locus_tag="VVR21_000873"
     CDS             complement(35723..37033)
                     /gene="obgE"
                     /locus_tag="VVR21_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU6054781.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(37097..37231)
                     /locus_tag="VVR21_000874"
     CDS             complement(37097..37231)
                     /locus_tag="VVR21_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU6054782.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(37290..37466)
                     /locus_tag="VVR21_000875"
     CDS             complement(37290..37466)
                     /locus_tag="VVR21_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6054783.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(37497..38822)
                     /locus_tag="VVR21_000876"
     CDS             complement(37497..38822)
                     /locus_tag="VVR21_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6054784.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(38838..39881)
                     /gene="cpoA"
                     /locus_tag="VVR21_000877"
     CDS             complement(38838..39881)
                     /gene="cpoA"
                     /locus_tag="VVR21_000877"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU6054785.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(39996..40325)
                     /locus_tag="VVR21_000878"
     CDS             complement(39996..40325)
                     /locus_tag="VVR21_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU6054786.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(40339..41448)
                     /gene="rpoD"
                     /locus_tag="VVR21_000879"
     CDS             complement(40339..41448)
                     /gene="rpoD"
                     /locus_tag="VVR21_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU6054787.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(41451..43211)
                     /gene="dnaG"
                     /locus_tag="VVR21_000880"
     CDS             complement(41451..43211)
                     /gene="dnaG"
                     /locus_tag="VVR21_000880"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU6054788.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPSE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDDNQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(43301..44059)
                     /locus_tag="VVR21_000881"
     CDS             complement(43301..44059)
                     /locus_tag="VVR21_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054789.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(44056..44922)
                     /locus_tag="VVR21_000882"
     CDS             complement(44056..44922)
                     /locus_tag="VVR21_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054790.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(44991..45995)
                     /locus_tag="VVR21_000883"
     CDS             complement(44991..45995)
                     /locus_tag="VVR21_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6054791.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(46108..46325)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(46408..49104)
                     /gene="ppc"
                     /locus_tag="VVR21_000884"
     CDS             complement(46408..49104)
                     /gene="ppc"
                     /locus_tag="VVR21_000884"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU6054792.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDVYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(49124..50353)
                     /locus_tag="VVR21_000885"
     CDS             complement(49124..50353)
                     /locus_tag="VVR21_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU6054793.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(50481..50734)
                     /locus_tag="VVR21_000886"
                     /pseudo
     CDS             complement(50481..50734)
                     /locus_tag="VVR21_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(50910..51162)
                     /locus_tag="VVR21_000887"
                     /pseudo
     CDS             complement(50910..51162)
                     /locus_tag="VVR21_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            complement(51444..52031)
                     /locus_tag="VVR21_000888"
     CDS             complement(51444..52031)
                     /locus_tag="VVR21_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU6054794.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYFLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
BASE COUNT        15671 a        11365 c         9151 g        15854 t
ORIGIN      
        1 tcgtattttt tctataatta ttattttata gcaaaaaaat aaaaccagga aaacaatttc
       61 ctggttttac acgttatttc acatcaaaaa caatggattt gacatttgtc atcgcttcaa
      121 tgctatattt aattccttgc actccagctc cagaaccttt gacaccaagg aatgggaaat
      181 tatctggacc acgctgggtt ttattattaa tgtggactgt acctacttca agtttttcag
      241 caatttcaaa ggcttttttg aaatcatttg taaagactga tgattgaagg ccgaattcag
      301 attcgttggc aaaggcaata gcttcctcta cactagccac acgaatgatt ggtaaaacag
      361 gaccaaatgg ctcttcccat gccactttca tatcttttgt aacttggtca aaaagcactg
      421 gccagaggag attgccctca cgtttgattg gtgaaagagc ctgagcctct ttttcttgtg
      481 catcctcaat caagccccaa atgaagtcgg ctgaagcatt gtcaataaca ggtgtaatat
      541 cagcattgtc aaatggatca ccaactgtta atttagaaac ttcttcctga agcaaagtag
      601 ctaatttatc tgctacactt tcgagaacaa tgacacgttt aatggccgtg caacgttgtc
      661 ctgagtagct aaaggctccc gcaacaattt gcttggcagc atgttccaaa tctgcatctt
      721 ctagtacaag agctgcatct ttcccaccaa gttccaacat gataggacgc ataccagcta
      781 aacgaccaat acgttctcca ataggagttg aacctgtaaa gttgatgaag ttgacttctt
      841 tgtgctcaat gatataatcc ccaatttctg aaccacgacc tgtaatggtg ttgaaaacac
      901 ctgccggaat ccctgcttct tcaaatgctt tagccaacaa gagtccagaa atggaacctt
      961 gtgttggtgg cttaaacatg accacattcc ctgcaatcaa ggcaggtgca attttagaag
     1021 cagataaatt aactggataa ttaaaaggag caatcgctag cacgatacca actggttcac
     1081 gacggacaac agccagtttg tttttacttg ctgcctcaaa accaccacct tccattgctt
     1141 gtccagtgat acggagacct tcctcagcag cataacgaat caagtctgct gtacgcacta
     1201 cttctccaat tgctgcttta atcccttttg ctacttcttt ggcaaggata gtaccaattt
     1261 tttccttatc gcgttctaaa atagctgctg ttttatgcaa ataagccgca cgttcaattg
     1321 ctgataaagc tcgccatgct ggcagggctg cacgcgcagc ttgcatagcc tcatcagctt
     1381 cagtctgagt catggctgga actgtaccca attcttcttg attgattggt gaataaatcg
     1441 taatttcttg ttcagatgat ttccattttc catttactaa attctgatat cttgtcaaat
     1501 tcttgtcctc ctgaaaatga ttaagatata ttttaccaaa ttttcagaaa atcacaaccc
     1561 tttttgcgaa atttttgaga ttattttcac aatcttggtt tttcaaagta tactcaataa
     1621 aaattaaaaa aatccactac gtcaaggcga ggctaatgtg gtttgaagaa attttcgaag
     1681 agcgtgaatg agtatcatct atagtaaaat aaaaaaactg aacaatttgg ttggggacag
     1741 ccaaaccaat ttctcacaat gtttcagaaa caagggtgtg ctattccaat ttcagcctac
     1801 tataactgtc atagattgct gaaacaaagt ctaggtaaaa gtcttcataa taaaaagacc
     1861 ccctatcaag tgttcaaaaa ctttgatagg aggtcttgtt ttgtgaaaat atttatcaaa
     1921 ttttctatac aagtgagctg ttagccagat tctttctatt ctttcaattt caatgaatgg
     1981 attttttacc aatactcata actgggaatt tttctgtcta aaaatagcga gatagatggt
     2041 atttataaaa cactcaagac agctagacta atatcattta aaacattatc ttcttttgag
     2101 cgactgttgg ttaccaacat agctaaattt cctgcatttt caaattgata gggttctgat
     2161 ttagcattca caactaccaa gaggtgttct ttgccgtgaa cttcatagat aaggcagccg
     2221 ctatgttcaa tcgcagaatg cacaaagaca tgatggtaaa tttcatcata gctagagtaa
     2281 gaaaaggcac cagtttttgt cttcaatcgg atgacttgac ggataaactc aatactgtct
     2341 tgacgctcat taatcaagtt ccagttcact tggttcacac tgtcaggagc attatagcta
     2401 ttcatcgcac gctctctatc atcatgggtc aactcaccat tttcaccagt cgcaaccagt
     2461 ttggtacgac caaattcttg accgatttcc ataaaggcca tcccctgcat gagcagattc
     2521 atggctgtgg cagtttcgac cttgcgcatg atttgctctg aactttggtc tggatgaagg
     2581 gttgccaata aatcgtgaag attgtaattg tcatgggctt ctacatagtt aagcacctga
     2641 tttggatgtg tatagcttcc taattcacga cttcctagga ttgctttagc tagaattggc
     2701 tctgtcgcag caccactgac aaaacctgac ttgatagcac cataaacttc tccccctttg
     2761 acagcatcgc gctgattgtc attaaagaaa ccaatatttg gcatctggta ggcattgtcc
     2821 ttcttggcct tatcataagg ggcaagacct gttcccatat cccatccttc tccatagagg
     2881 ataatgttgg agtcgatttc atccaagctt tgacgaatca tctgcatggt cttgacatca
     2941 tgaatcccca tcaagtcaaa acggaagccg tcaatattat attcctgcac ccagtataga
     3001 agagaatcaa tcatatactt gcgaaacatt tcgtgttcac tggctgtttc atttccaaca
     3061 cccgttccat tctggaaggt accatctgga ttcatacgat aatagtaatc agggactgtt
     3121 gtttggaatg gtgcatcaac aactgagaag gtatggttat agactacatc cataatgact
     3181 ccaatacccg catcgtgata agcttgaacc atcaccttca aatcacgaat gacctgagct
     3241 ggatcatctg gattagttga aaaactagtt tctggcgcgt tatagttttg tggatcataa
     3301 ccccagttgt aggttacatt tccatcctca tcgtattctt tatgacggtc tgcaattggt
     3361 tgcaattgaa cataattgta gcccagcttc ttgatgtaat caaaagcagt tgactggccg
     3421 tattggttaa ctgttccagc ctgagcagca cccaagaaag ttcctcgaag atgttcatct
     3481 acacccgatg taggtgattt agtcaaatca cgaatgtgca tttcacagat aactgcctta
     3541 catggatttt ccaagcgcca agtagcctcc gaaccgtgct taacctcgaa gttttcaact
     3601 tgcttttcta catggctcag aatagctgaa cgtttgccat cagggctggt cgcgattgta
     3661 taaggatcac gtgtcagtgt ttggtgatga gagaattgga cttgatactg ataagtctta
     3721 cctaccaaat cttcttcaac atccaaactc catacaccga ttgtattgtc cttatgatta
     3781 taagagtagc tattgcctct tttcatctca aaagtcttcc aaacgggtgc atcattagca
     3841 gctgattcat aaacgacaac ttgtacttct gtcgctgtag gtgaccagag ggaaaaatga
     3901 gcctgattgt cctctacacg gcaacccaat tctccttggt aaccccaatg atgatcaaaa
     3961 ctagcactgt taatggcctt atcaaaggca aaaggatttt gatttttata gaaaggactg
     4021 gcaatagcag gattttcaga gtaataaatc ctatcatcgc cttccaaaat ccagacctct
     4081 gttaataggg gatagtgatt aaaacggata gaatattctt tactagtttg acctgtatga
     4141 accacaaaat tcaagctttc tataacatgt gaacttgggt gttcaaagct aaataaagct
     4201 ccaaaataat cttctttgta ggttagcaaa tcaattcgtt gatcctgact ttttacaaag
     4261 gagcaagtgt catattctcc attcttacga tggtaatgaa tgcgcatagg gtagttatac
     4321 attttttatt tttccttttt actttgtttc tatttcacta ataaattttt gtcaatctcg
     4381 tctcaattaa cagacatagt catattctct aaactctgtt tttaaacgat ccattacaaa
     4441 ctttctagcc atgcctcatc tctgacctgg ataccaagtt cttgtgcttt ttgcagttta
     4501 cttccagcgt ctgcacctac cacgacgagg tcggtctttt tagaaacact acctgtcact
     4561 ttggcaccca gactttcgag tttactttta gcttctgagc gcttgagtcg ttccaatttt
     4621 cctgtcaata ccacggtcaa acctgacaag gccgcatccg ctactaccgt ctgtccttta
     4681 tagtccagat tgaccccagt ttctttcaat tctctgagca gaatttcaga gccttctgtc
     4741 gcaaaataag tctgaagact tttggcaatc acgccaccta gactttcaat actagccact
     4801 tcctctgaat ctgcctgata cagattttca attgaatgga aatattgaag taaaagctga
     4861 ctagccttgc ttccgacatg acgaattccc aaaccaaata agagcttctc ggcagaattt
     4921 tcctttgatg cttggatagc ctgatacagt ttagcagcgg acttttcctt aaccccctct
     4981 aaaaggagga aatcctcttc ttgcaaacga taaatatccg ccacatcctt gactaaatta
     5041 gcagcaaaaa gcttctcaac aatagatgga ccaaggcctg taatattcat agcatcacga
     5101 gaagcaaagt gaatcaagcc ttccatgatt tgagcagggc aacgcggatt gatacaacgt
     5161 agggccactt catcttcaaa gtgcaacaag tcagagttac aacttggaca gtttgtaggg
     5221 atatctagtt tttcttcaga gacccgtttg gactctacca cacgtaaaac ggcagggatg
     5281 atgtcaccag ccttatatac aatgaccgta tcgtcttttc ggatatcttt ttcagcaata
     5341 taatctacat tgtgcagggt cgcacggcta acagtcgtac cggcaagttg tactggtgtt
     5401 agattagcag ttggagttac aacaccggta cggccaactg tccagtcaac tgataagagt
     5461 tgagcttctt tttcttcagc agggaacttg taggctactg cccactttgg agccttaacg
     5521 gtaaaaccaa gttcttcttg acttgctagg tcgttgacct tgattaccac tccatcaata
     5581 tcgtaaggca gattttcccg ttcctgtcct acttcttgga taaaattcca gatttcatct
     5641 atgttttcag ccaagattcg cttaggattg accacaaaac ctagttgttc taggtacttc
     5701 aaaccctttt cttggctatc acgagttgaa gggctggctt cttgatagag aaacgttgcg
     5761 agattacgct tggcaactac tgctgtatcc aactgacgca gagttcctgc tgccgcatta
     5821 cgaggattag caaattcagg ctctccattt tcttggcgcg cttggttaac ttggtcaaag
     5881 gaagcgcgtg gcatgtaaca ttccccacga actgtgatat ctagttcttc tgtcaaagtc
     5941 aaagggatgt ccttaacacg cttgaggttt tctgtgatat tttcaccaat tgaaccatct
     6001 ccacgtgtta ccccagcaac caaaatcccc ttttcataag tcagcgagat agataagcca
     6061 tcgattttca gctcacaaat ataggtcgga tgagccactt ccttacgaac acgcgcatca
     6121 aaagcatcta gctcctcacg tgaaaaagca tcctgcaaac tataaagagg atactgatga
     6181 ctgtattttt caaaaccatc taaaaccttg ccaccaacac gatgagtcgg actgtctgct
     6241 agcacttgct ctggataagc agtttctaac tcgaccaact cacggtaaag gcggtcatac
     6301 tcactgtctg aaaccgaggg attatcgctg gtatagtact cagtcgcata gcgattgagc
     6361 aaagcgacta actcattcat tcttttattc ataagaccat tttaccataa aacaagccct
     6421 cctcacaaac gagaagggcg gaaaaaacac ttagtttgaa attatttttg aaactcaagc
     6481 aaccttatat caatttttca aaatgagttc gaacataaat aaacgatata caagacaaga
     6541 tgataacacc acttccaatt atcaggaaag aagagagatg tacacttggc aagactgtca
     6601 taaatccttt tgcaataggc ataaatagaa tagctaaggt aaaaattgta ctcagtactc
     6661 tcccaagaaa ttcgctctca accttggttt gtacttgagt aaaaaagtga atattaaaaa
     6721 tcgtcataaa caattcacaa actaaatttc cagaaaagga aagaaaagtt ggaagtggta
     6781 atcccatcat aaaaactccg acacctgtca aagccagtaa aatcaaaaga ttataaatat
     6841 tagctttaat tttactagct agaagagccc caatgatgga accaatagcc cccatagtta
     6901 aaatacttgc ataggctcct tctgacccgt aaagctgatt cgaaaaggga agtagaaatt
     6961 caaaagctgc aaaaaagaaa ttaacgctgg aagctaccag caaaaggaag aaaatttctt
     7021 gctgatgcca gatatagtgt aacccatcct tgatatctac aaaaatatct ctcccagtaa
     7081 aagccttttt ctcttgaact tttgcttcct cttttggaag gaaagccact agaacaaaag
     7141 caatgaaaaa agtcagcgag tctagcagta gcgtcatatg gagacttgca aactgtaaaa
     7201 caaggaagga aagaacagga gagctaacac ctacaacctg caaaaccagc tctaagcgag
     7261 aattatagat cacaatctca tctttctcca ccacttcagt tatgatagct ttattggctg
     7321 tgcgagaaaa ggcaaaagca atagcctgca caatgttagc aacaatcaaa gcgccaatca
     7381 tccagctatc attccttatg aaagaaatag ccagacaaag aatcccacaa acaagatctg
     7441 ccgtcattaa aatcttacga cgagaaaaac ggtctgaaat aactccgcca aagggattga
     7501 cgagaataga tgtgacgagc tcagaaatct gatacattcc taaaactgtc tgtcctatag
     7561 tccccataga agccaaccag acactatttc cataatcata gagcatattt cccattttat
     7621 tgatagcccc acggctaatc aactgcactg catagcgatt catattaaag ctcctctcaa
     7681 attttgaaac tattgtatca aaaccgaaag gagcttttta ttttttccct tatttgggaa
     7741 aattaacttt tgacaaattt ttcgtagtgt tcctgataat aggctacttg ctctggaaga
     7801 cctaacacat caaaaatatg catggcctct tgcatctgct tacagccttc tttacactgt
     7861 cctttttgat ataaggccaa accttttaaa taatggaaaa cattacgctc ataaagctta
     7921 atacctttgt caataatctt ctctgtataa gcctcaaaat agttggcatt ataaaaagaa
     7981 gaatgctcta aacaatgctg gtaacaattg agggccaaaa ttaacactaa tctcttatgg
     8041 cgactaatct cttggtaaaa ttcctccctc tccataactt ctctaccaat ccgagtgaca
     8101 tagtctacat cgtagaaact atagaggtta ccgaaaagaa tcaactcata catggtccat
     8161 tcttctgttt tgaagagata atctgctacc ttatccaaat catcctgctt catatcataa
     8221 ctcgcatctc tttgacaaat cagaccttgt agcaaaatcc agttcagctc aaaataaagg
     8281 gaagtcgtcg aactcttaga cttttcaagt tgttctcttt gaagcttttg aaaacctgca
     8341 atatcgtttg aatagtaaag tgggataatc tgtgccatca tagacacatg ttcatgatta
     8401 tgaaaattcc ttgccttatc catgaaattt tcgattgtta catgaatgtt atccaaaatc
     8461 tcaaagaaac gggagactgc caggtcagac tccccaagct caaagcgaga taactgagag
     8521 gtagagcagg attcgcctgc tgcttccttt aaagaataat ttccacttgt tcgaaattca
     8581 cgaaatactt ttccaagatg ttccatcttt acacctgatc tgataattct tcccactcaa
     8641 gcatagcttc ttcctgacga tggctgattt tatccagctc agcctgtaat tccatgagtt
     8701 tgtcggcatc gtttgtttcc aacatttgtt cagaaatggc ttggctttga ctttctagct
     8761 cttcaatttc agcttctaga ctttcgattt gtcgcatgag tttgcgaact tctttttgac
     8821 tttctttctg ggcctgatag tcattgactg gacttgcttc ctttgcttga ttgctagttg
     8881 aagcttcctc agtctgactc atttctgctg ttgctttctt ctcaacatag tagtcgtaat
     8941 ctccaaggta gagagttgaa ccattctcag acaattccaa aacatgagtt gccacacaat
     9001 tgataaagta acgatcatga ctgacaaaca gcaaggtacc atcaaagtca atcaaggcat
     9061 tttctagcac ttccttacta tcaatatcca agtggttggt cggctcatcc agaatcaaaa
     9121 agttattgtt ttccatagac aatttagcta aaagcaaacg agctttttcg ccaccagata
     9181 gcatgccgac tgatttttta acatcatctc ctgagaaaag gaaggctcca agacggttgc
     9241 ggatttcaac ttctggtgtc agtttgaaat cattccagag ttcatccagc accgtattac
     9301 ttggtgtcag cttgctttgg gtttggtcat agtaaccaac ctcaacatta gcgccaaagc
     9361 gcttttctcc cttgataaac ggaatttgat ccacgattga tttgataaag gttgattttc
     9421 cgataccatt gggaccaacg atagcaacag cattcatctt acgaaggtct aggttaatcg
     9481 gttgtgacag gacttcccca tcatagccaa cagccgcatt ttcaacagtc aaaacaacat
     9541 tgcccgacgt tttttcagac tggaaggtca tgttggctgc tttcttgcca gcttccggct
     9601 tgtccaaacg ctccattttt tctagttgtt tacggcgaga ttgagcacgt ttggtcgttg
     9661 aagcacgaac tagattgcga ttgacaaagt cttccagagc agcgatttcc ttctgttgct
     9721 tttcatagtt ttttgcctca gtagctagct tttgctcctt caactcgaca aaacgagagt
     9781 aattccccac atagcgatcc aaggaatgct tggtcaaatc tagcgtaatt gtcgcaacct
     9841 tgtccaagaa ataacggtcg tggctgacga taatgagggc tccgctatag tttaccaagt
     9901 aattctctag ccaggagatg gtttcaatat ccaagtggtt agttggctcg tccaagacca
     9961 agagattggg cttttcaagg agcattttag ctagagccaa acgagtattt tgaccacctg
    10021 aaagttcagc tattttcatc tgccacatag actcgtcaaa cttgaatcca ttcaaaatcg
    10081 ctcgaatatc agcttcatag gtaaagccgc ctgcttggcg aaaattctca gataagtggt
    10141 cgtaatctga catcagttta tccaattcat cgccagactt ttcacccatc tccaactcca
    10201 tctgacgaag ttgtttatct gtccgacgta agtcatcaaa gacatgaagc atttcatcgt
    10261 agatggtatt ttcagactca aaacggctat cttgggctag gtaagacaga gaaatatctt
    10321 ttttcttatt gatttctccg ctagttggct cctcttctcc aactaaaatc ttcaaaagag
    10381 tagacttacc tgcaccattt ttcccaacaa gagcaatccg atctcgttca tcaacctgca
    10441 ggttgatatt atcgaaaaga acctctcctg caaaagaacg ttcaatttta ttagcttgta
    10501 aaataatcat acaagtagta tagcatgttt ccctaagtca ttcaagataa tcgtaagtct
    10561 tttagtacaa cttttataac ataaaataaa ctaaattatg tatattttat attagattcc
    10621 ttcactatct tgttggattt tctaaccagc taatcttgtt tcaaatagtt atcgcacaag
    10681 tctattattt aattcttttc attatttacg tacgtatagc agattgaaat aagatgagaa
    10741 caaatcgatt gggaaagtaa aattaatttc tataaatgtt ttagcaattg tttcgtacta
    10801 ttttagattc agtctactat atacaatatt ttcggaacat tcaacttttt aactctattt
    10861 attactaaat ttcataatta aaaagcctac tgaccaagct agaaagcttg atacaatagg
    10921 ctttttaaag actgattatt taacagcgtc tttaagagct ttaccagctt tgaatgctgg
    10981 tactttagaa gctgcaattg tcatttcttt accagtttgt gggttgcgac ctttacgttc
    11041 tgcgcgctca cgaacttcaa agttaccaaa accgatcaac tgaacttttt caccagctgc
    11101 aagatagtca gctactgctg caaatacagc ttcaactgct gctgctgagt ctttcttagt
    11161 caattctgta gcttctgcta ctttagcgat caaatcttgt ttgtttgcca tgttaatgat
    11221 tcctccaaat aatttctaat taacaaatat aatcatatcc taaaatccct tttaggtcaa
    11281 gttaaaaacg ctatttcttc ccattttatt tattttttta ggagtggtaa cgtatcaaaa
    11341 tagcccaagc gttctcaccc gtgtgagttt gaataatgga acccgtttcc aaaacagaaa
    11401 ttggcttttc aacataagct tgtaagcttt ctttcatctc ttttgcccaa tcatcactac
    11461 cagaatatga aattccaatc tctgctacag cacgttcaga aagcgatgtt atcaactcat
    11521 ctaaccattt tttaaatgtt ttagttccac gacctttaac cattggctgc aattcatggt
    11581 ctttcatttg catgacagca cggatattga gaagagagct caacaagcca gttacacggc
    11641 taattcgtcc acctttgaca agattttcca aagttgaaac accaatataa agctctgtat
    11701 ggtttttaac ctcttctaca tgagataaaa ttgcctccat atctttacct tcttgagcta
    11761 acttcgcagc ctcaacaact tggaatttca gggcttggtc agtgaaggaa ctatcaacaa
    11821 cagtcacatc tgcagtagat aggctagcac cttggcgtgc tgcttctacc gtacccgaaa
    11881 gagcatggga catatgaata gcaagaatat ggccaccatc tttgcatagg tcttcaaaaa
    11941 tctcagcaaa gacacctaca ggtggctgac ttgttttcgg aagattctta ctttcttgca
    12001 tcaactgaag aaatttacct tcttctttca aatccgcatc agaataaaca acattatcaa
    12061 tcattacaga taatggaaca attgtaatat ctaattgctt tactagttca ggttcaatag
    12121 taacagatga atcggttaca atcttaattt ttgtcatagt atcaatcttt ctattttagg
    12181 attcagattg gtttccttac ttctaattat atcaaaaaaa agattaaaaa tcctaatgga
    12241 gtcaatcaaa ttttccgtaa aatttgatat aatcaactta taagaaaaga ggtgtcctat
    12301 gattaaaaaa atttacccca tttttaccat tttactaggt gctgctattt atgcttttgg
    12361 actgacttat tttgtagttc cccatcatct ctttgaagga ggggcgacag gcattaccct
    12421 catcaccttt tatcttttta aaatccctgt ttccctcatg aacctgctga ttaatattcc
    12481 ccttttcatc ctagcttgga agatttttgg agccaaatcc ctctattcta gtttactagg
    12541 aaccttagct ttgtccggct ggttagcttt ttttgagcat attccccttc atattgatct
    12601 tcaaggtgat ttactaatca cagcccttat agcgggaatc ctattgggaa ttggccttgg
    12661 aattattttt aatgctggag gtacaactgg cggaactgat attctagctc gtattctcaa
    12721 caaatacact catatatcca taggaaaact gctctttatc ttagattttt gtattctcat
    12781 gttgattctc ctaatcttca aggatttgag attggtttcc tacacgcttt tgtttgattt
    12841 tattgtttct cgtgttattg atttgattgg tgaaggagga tatgccggca aaggctttat
    12901 gattatcaca aaacgtcctg accaacttgc taaggcgatt aatgatgacc tcggaagagg
    12961 tgttactttt atttctggtc aaggctacta tagtaaagaa aatttgaaaa tcatctactg
    13021 tattgtcgga agaaatgaaa ttgtgaaaac gaaggaaatg attcatcgaa tcgatcctca
    13081 agcctttata actattacag aagcccatga aatcctagga gaaggcttca cctttgaaaa
    13141 agaataaaaa gaggtaatgt cgtgacctca aaagttagac taaatcatct atcttttggg
    13201 ttacagacaa cctctttttt attttattta ctcaagctct taagaccaat tccgagttac
    13261 ttcttcatca gcctttaact gatccactaa ttggtcaact gagtcaaatt tggtcatatc
    13321 acgaatgcga tcaagccaat aaaccatgac ggtttcccca taaatatctt gattaaaatc
    13381 aaaaatattg acttcaaaac gtgcttcttc tccatcaaag gtcacatttt tcccgacact
    13441 agccatagca cgatacttct gtctttgaat ctcaacatca acgacataaa cgccatctgc
    13501 tggcatataa gtacggtcta aaagcactaa attcgctgtc ggataaccaa ttgtacgacc
    13561 acgagcatta ccatgaacca ccatacctct tgatggaagc ggtgccccca aaagttttcc
    13621 tgcttctttc acatttccat ctaaaatagc ttgacggata cgagttgaac taatctttcc
    13681 tttctcatct tctacaggtg gaacaatgat aacttctcca tcaaagtaat cctttaaatc
    13741 ttctgctgtt tttttgtcag aaccaaatgt ataatcaaaa cctgcaacaa taattttggc
    13801 attcatagcc ttgatataag ttgcaaagaa ttcttgtgca gtgagactag cgaattgact
    13861 actaaaatca aggagatata attcttctac accttcgcgc tttaattttc tttcacgttc
    13921 agcagggttc aaaatatgca aaaacaaatc tggatgataa ggctctaaag cgatctttgg
    13981 agattcatta aaggtcataa cgacgatagg taataaatcc tttctcgcag ccttgttggc
    14041 aacacgaaat aattcttgat gccccttatg tatgccatca aaatagccga gaacaacgac
    14101 tgaatcagat ggtgtgccaa tatctttttg gttttttata ggaatagtaa taatcataaa
    14161 ataattatat catagcgata gctatttctg gaacagaaaa tctgaaatgt tgtttttttc
    14221 acatgaagtg tacctgtttt caaaaagcac tttattctat cgttgcttaa ctatgaactt
    14281 tgcaatattc ttctcaaaaa cttgtaggac atcttcaaaa ttttgcaagg agtgattaga
    14341 cttgttcggt aaccataaag tgtcatacta tgcttatgta tgaaaaagca atgcaactaa
    14401 ctcctgagaa ctttaaatta ctaattggtg ccgaaaaggt agaatttaga atcgaggtac
    14461 acctatggct gtaaaattta caaaatgaga caacttgggc aagatgtttg aagaatttcc
    14521 taaactccct gatttgaagc aagtcacttt ccctgatgac aaagaaaaaa gccaaaacag
    14581 caaagaaaaa ctagatgact gctttccaac aactcccatc tagtgtgctt cagactgggc
    14641 tatttttctc tccatctgtt agcttggatt ctcagacagt ttcagctaaa gaatatcttt
    14701 tcccttatca gaaggaacgg ctcaaaccat tcagacaagt gaagggacga caagccaata
    14761 tttgaaacca gatagcagtt cttatagtca attgaaataa aatctgaaga aatcgagtag
    14821 gaaactcata tcaattttta acagtgttct attccagatt caatccacta tacatattaa
    14881 aaagtatggg taccaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta
    14941 agctgtttct agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac
    15001 ctttttattt agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa
    15061 agcgtactac gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta
    15121 cacctggata gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt
    15181 gtccgtcagc tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag
    15241 aacctccacc ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa
    15301 tgttttcctc cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc
    15361 tccgataagt ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc
    15421 tggtgtgaag gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt
    15481 aattctagga ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca
    15541 agcgtagaaa ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca
    15601 gtaatttccg cactcctcag ctcgccatct tcggctctct caaagactgc ctgtatcatg
    15661 tgttctcctt aaaattaagc gttgattgcg ttgatgacaa cttttgtata tggttgacgg
    15721 tgaccttgtt tacggtggct acctttttta ggtttgtact tgtaagtaac cactttcttt
    15781 tgttttcctt gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg
    15841 acaacagtgt tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct
    15901 tcaacgttca atttttcaac gtaaactgct tgaccaactt caactttaac ttgttttccg
    15961 ccagttttga taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc
    16021 ccgatttttt gtgaagactc gcctagcatc gtgggacgaa ccacttaaac ttgaataatc
    16081 aagcaacgat gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca
    16141 tatctcctat tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt
    16201 ctgccaagag gcaaaaagca tgctgaggta aaaaacgctc atcataatag gaacaccaag
    16261 aatggtcttt tcatgataga aaatcgtcaa ataggctgaa aagacaacgc caaggacaaa
    16321 actactaagc aggctaacaa atatgaatcc ttcacgcaaa aaaggagtgt gcttggttcg
    16381 gaaataatct ccaaaagcca gcatggtccg tttgatattc cctgtcataa aagcgttatt
    16441 ataggcaata cccgacactt ctccaaaagc agttgtcacc agtcccatac agaaggccaa
    16501 gggcggcact agatagatat tatccacagt ttgcggcaca aaagcaataa tgattgataa
    16561 gattgccaag ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata
    16621 aatcgttaat aaaaagactc ccatcataaa cgctagcaag gtgagaacct tgtccctaac
    16681 atccgaaaca ttatttttaa ttaattctac tgaaagaaag acaacatttc cagtttgtcc
    16741 agctacaagg gtattcccgc gaacaataaa agtgtaagca tccacatatc cagcacaaaa
    16801 cgtcaaaaaa agtgctaacc ttttagactg acgtgatatt tttcttatag gtaataacct
    16861 cattttacct cccattgtat tttctcttag aaatattgta ccattttctt tctaaaaaat
    16921 cgtaggctac catttagatt ttactattag cataaaaata ataatagaca actatttatc
    16981 caaaaataga tagatgtaac atgtttgcaa acaaagcata cgaaccttta gtaaaatcat
    17041 ttccatgaaa ctagaataga gccctcttag caaaaatcat tattttaatt tatttctaat
    17101 cactccttga cataaataac tctcaccaat aaaagactat gtcttaaaaa aatggtataa
    17161 taaaatcaat acttgggctt gatggctatg ctactaataa caattaggag agaaaatcag
    17221 gcacttgtta acaacaagga ttatcccctt gagatgaaag gaactttaga aatcttatga
    17281 tgaacatgca aaacatgatg cgtcaagcac aaaaacttca aaaacaaatg gaacaaagcc
    17341 aagctgaact tgctgctatg caatttgttg gcaaatctgc tcaagatctt gtccaagcga
    17401 ccttaactgg cgataagaaa gttgtcagca ttgatttcaa tccagctgtc gttgacccag
    17461 aggaccttga gactctttct gatatgaccg ttcaagccat caactctgct cttgaacaaa
    17521 tcgatgaaac taccaagaaa aaactgggtg ctttcgctgg gaaattacct ttctaaaaac
    17581 aaggagctag aacaatgctt gtcgataaca aagattaaga aaggtgcaaa aattataaaa
    17641 aacgcataat agcaggtgtc aagacactta atattatgcg ttttctcatg aaaaattctc
    17701 ttttcatact catttaaaat caaaaaggga aattatcgtt ttacggacat acatattaca
    17761 gatttctata ggtcgtgtat agacaggata tcatcgcttg gaagttttcc tttttgacac
    17821 caatcagtaa tttagttctc aggaattaat ggcagtgctt ttcgtacata gtttcataac
    17881 tacagtatag catagtatat cgctttatag ttttcactat tgatgaactg cttgagctgc
    17941 tgtgatgagg gtcaacttgt aaacatcatc tgcattacat ccacgagaaa gatcattaac
    18001 tggcttgttt aaaccttgca aaacaggtcc tacagccgca aagccaccca ggcgttcagc
    18061 catcttgtaa ccgatatttc ctgcctcgat acctgggaag atgaagacat ttgcttgacc
    18121 agctaccgta cttccaggag ctttcagagc tgcagtttca ggaacaaagg ctgcatcaaa
    18181 ttgcaactca ccatcgattt caaggtcagg acgcaagtcg tgagcaattt tagttgcttc
    18241 aacgacctta tcaacgcttt caccaaaccc tgaaccttta gtagaatagc tcaacatggc
    18301 aattttaggt tcgatgccaa acatcttagc tgtgattgct gagttgatgg caatttcagc
    18361 caaggcttct gcatctggat tgatgttaat ggcacagtct ccaaataggt aacgttccgt
    18421 accacgaacc atgaggaagg ctcctgaagt acgagttaca tttggacgag ttttgatgat
    18481 ttgtagagct ggacgaactg ttgaagctgt tgagtgaatc gctcctgaca ccattccatc
    18541 aaccaagccc aagtaaacca acatcacacc aaagtagttg acatcttcaa ccaaaacctt
    18601 gcgtacatct tcttcagtca ttttgccctt gcgacgctcc accaaggcag aaaccatttc
    18661 ttcaaattga ggataatgtt gagggtcgat gacctcataa ccatccatga ttccttcaat
    18721 ttcaagataa attttaactt tttcaggatt tccaagcaaa acaggaatca cttctgtttc
    18781 ttttactaag cgttttgttg cttgaagaat acgaggctct tccccttcag ggagaacgat
    18841 acgagcattt ttaccaacaa ggttggcttt gagactttca aaaacttcca tgagttttct
    18901 cctttaagat aataattata ctctgagaca gtttttatag agtattagtt gataactggg
    18961 taataaggtt actgaaatca tccggcaagg gactttctaa ctgcaagtct tgctctaaaa
    19021 atggatgata aaaggatagg taatggcaat gcagagcctg acgttgaata ccatcttcca
    19081 gactaccacc atacaaatca tctcccagca aaggaaaacc gatatgagaa aaatggactc
    19141 ggatttgatg ggttcgacca gtgtgcaggt gaatatagac caagtgaata tttccataag
    19201 aagctacaat cttgtatgaa gtatgggcat actttccgcc tttagccact cgtctggtaa
    19261 taatggaatc ttcatcacgc gcaatcggag caataatttc cccttctggc tccaaatgtc
    19321 catctccctt aaccaaagca aagtagcgtt tctcgataga tttcttctgc aactgcttgt
    19381 ctaatcgtgc atgggcataa ccgtgcttgg caaagagcat caagccagaa gtgtccctat
    19441 ctagtctggt aacaatgtga acctgctgat tttcataatt ttgcttgaca tagtaaccct
    19501 tgataaaatt ggcaatggta ttagagtgat tgacactagg aatagaagcc actccatagg
    19561 gtttattcaa gactagaaag tggtcatcct catagagaat atctaatgga tgctcaatag
    19621 cctccaaggt ttcaaagcct tcctcagcgg gaatgtaaat ggtaacgtag tctccaacgt
    19681 ccaatagata cgttgcattt tgcggttgat tattgaccag aatagctcca cctcgaaact
    19741 taatcttagc cagcaatccc ttagaaacct cgtgcttttt taaaaaggtc ttaaccttga
    19801 catgttcatc tgcgataaat tcaaacctca ttcatccacc tcaccgataa aggcatcctt
    19861 aacacggttc cagaaactgg tatggctagg agtcgcgaca aagtgaatct tatgatggtc
    19921 gatttgatac tcaatacgct caatattacg gaaagaataa acgctattgt caaccgaaat
    19981 agtatgataa tcgtttcttg ttggaataag ttcaatctta tccttcttag gcacaataat
    20041 ggaagagccc agtgttcgat aaacacgatt attaaggctg gcaatttccg ttaattgcaa
    20101 agcttcaatg gtagggtgta aaacagcacc gccaagagac ttgttatagg cagtactacc
    20161 agtcggtgtc gaaactgtta gcccgtctcc acgaaaacgt tcaaagggaa caccatttat
    20221 tacaatatct gccaccatgg ttcgatcaga cctgcggatg ctggcttcgt tgagtgctct
    20281 gaaaatctta acttcaccat tttcaagaaa gaccttcaca ttcagaacag ggtaagaaac
    20341 ccttgcccca gtatctagct gcaaattagt cactagcttg tccaactcaa aatcacgata
    20401 atctgtatag aagcccaaat gtccagtatg aagaccgata aagcggacct tgtcaagctg
    20461 attttcgtac ttatgaaagg ccgacaagag cataccatcc ccgccaatgg aaatgacaat
    20521 atccggattg gtatcattga gtataaactg atttctcttc aaacgatctc gcaattcata
    20581 caaaaccctt tgactctgcg gttttctatt ggctatcaga tcaattcgtt tacctgtatt
    20641 cttcatctgt atcgtcactg tttcctacac cgtcatttaa ttttctactc aaaggatcaa
    20701 aaagtgcctg ggcttcttgg atatcatcac gaatttcacc catttcttca tccaactgat
    20761 gggcgattct agctgtaatt tccagtcgct tcttaatctc atctgggaaa tccccttggt
    20821 acttgtagtt gagagaatgt tctatcgttg cccagaaatt catagccaaa gtacgaattt
    20881 gaatttctgc caaaatagtc ttagctccat tgatggtatc aaccgtatat tctactacca
    20941 catgatagga acgatagcct gatgcttttc tatgagtaat gtaatctcgc tcctgtatga
    21001 ttcgcatatc ctgacgcttg tgcaaaatat ccactacttc cttgacgtca tctacaaact
    21061 gaaccatcac acgtaagcca gcaatatcct gcaaatcgtg ttccaaggtc gcataagtaa
    21121 tgccacgacg agccattttt tctttgatgc tctcaattgg cttgactcga ccggtcacaa
    21181 actcaattgg agaatgctta ttttgcttac gatattgctt acgaatacca cgaagtttaa
    21241 tctttaactc accaacagct tgaatgtaag gatctagaaa ttcttcccat tctaaggtca
    21301 tatattctcc cttgttctca tattatccgt caaaaatatc tttgattttt tctccagatt
    21361 catatacaat aaatacaatg cttattatac cataaatccg ctttcaacga taaaaaaagg
    21421 taagaaaaat gaaacattta gaaattgaat tgaaaacact attgaaaaaa gatgaataca
    21481 atcgtctaaa agaccagttc acaggtgtca ctcctgttct tcaaacaaat tactacatag
    21541 acacgcctga ttttgaactg cgagaaaaga aagtcgctat gcgcattcga acctttgaag
    21601 actgggctga gttgacactc aaagtcccgc agagtgttgg aaacatggaa tacaaccaaa
    21661 aattgcaact aaaagatgct gaggactatc tgagtaagga agaacttcct caaggactag
    21721 tactggatga attggcgaaa catggtatcc aaagtaagaa ctggcaggtt cttggttgtc
    21781 taacaacgct tcgctatgaa atgaaaacag ctattggtct catggcactg gatcagagcc
    21841 gatactttga tatgacagat tacgaattgg agcttgaagt ggaaaatcat gagcaaggca
    21901 aacaggattt ccgacaattt ttagagaaaa atcagatttc ctaccaaaaa gctccttcaa
    21961 aattggttcg atttgtcaaa agtatgaaaa atagctgaaa taatctccat tttttggtaa
    22021 aatagaaaag ataaaaatac acaaacccta gttatatgta aggtaaatat aactaggatt
    22081 tataaagttt acagaggacg gtctataatg tcagatagaa aaaacatgaa acttttcgca
    22141 ctcaactcta accaagagat tgcacagaaa attgcccaag ctgttggtgt cccacttgga
    22201 aaactatcat cacgtcaatt ttcagacgga gaaatccaag taaatatcga agaaagtgtc
    22261 cgtggttatg atgtttacat catccaatca acaagtttcc ctgtcaacaa ccacctaatg
    22321 gaactgttaa tcatggtcga tgcttgtgtg cgtgcaagtg cccacagtat caacgttgtc
    22381 cttccatatt ttggctatgc acgtcaagac cgcattgctt gtcctcgtga gccacttaca
    22441 gcaaaactag ttgccaatat gctggttaag gctggagttg atcgtatcct gactcttgat
    22501 ttgcatgccg ttcaggttca aggtttcttt gatattccag tggataatct tttcactgtt
    22561 cccctattcg caaaacatta ctgcgataaa ggattgcttg gttcagatgt tgttgtcgtt
    22621 agccctaaaa attcaggtgt caaacgtgcg cgtagcctgg ctgaatatct tgatgctcct
    22681 atcgccatta tcgactaccc tcaagacgat gcaactcgta acgaaggtta tattattggt
    22741 gatgttgaag gtaagaaagc tatcttgatt gatgatattt taaatacagg acgtaccttc
    22801 tctgaagctt ctaaaatcgt tgaacgtgaa ggagctacag aaatttatgc tgtttctagc
    22861 cacggtctct tcgtcgaggg agctgctgag cttcttgaca atactaatat taaagaaatt
    22921 cttgtgactg attcagtagc aacaaaagaa aaaactccta aaaatgtatg ctacatcact
    22981 gctagtgagt taattggtga tgctatcgtc cgtattcacg aaagaaaacc agtcagccca
    23041 ctctttgcct acaataaaaa gaaataaggt gattctttga tttatttgga caatgctgca
    23101 acgactccta tgtcagcagt tgctatttca gctatgacca aggttatgca agaaacccac
    23161 ggaaatcctt ctagtattca tggtcatggt cgtcaagctg gcaaactctt gcgagaagcc
    23221 cgtcaggaac tagcccagtt actaaggaca aaacctcaac atatcttttt cacttctggt
    23281 gggactgaag gcaataatac taccatcatt ggctactgtc ttcgtcacca agaacaagga
    23341 aaacatatca tcacaactgc catcgagcac catgctgtcc ttgaaacaat tgattacttg
    23401 gttcaacact ttgggtttga agcaaccatt atccagccag aaaatcaaga aatcacagcc
    23461 cagcaaattc aaaaggcttt acgtgacgat acgattttgg tttctaccat gtttgccaat
    23521 aatgagacag gaaacctact gcccatcgct gaaattggcc aaatactcaa gcaacaccct
    23581 gctgcctatc atgttgatgc agttcaggct attggtaaaa tcccaattca ttcagaagaa
    23641 ttgggcattg attttctcac tgcttctgcc cacaaattcc atggtcctaa gggaatcggt
    23701 tttctctacg catctagcat ggactttgat tcctatctac atggcggaga ccaggaacag
    23761 aaaaaacgtg caggaactga aaatctgcct gccatcgtag gcatggttgc agccctaaaa
    23821 gaagacctag aaaaacaaga agaacatttt caacatgtac aaaatctaga aactgccttt
    23881 ctggcagagc tggagggcat tcagtattac ctgaatagag gaaaacatca tctcccttat
    23941 gttctcaata ttggatttcc tggtcagaaa aatgacctct tactccttcg gctagattta
    24001 gctggaattt caatctctac tggctcagcc tgtactgcag gcgttgtcca atccagccat
    24061 gttcttgaag ccatgtatgg cgcaaattca gaacgcttga aggaatccct tcgcatcagt
    24121 ttgtcgccac aaaataccgt tgaagaccta caaaccctcg caaaaacctt aaaagaaatt
    24181 atcggaggtt agccatatgg catttgaaaa aatcattcag ttaaaaaatt gtcgttacga
    24241 ttacactctt agcccttctg ttaaaaaatt caccctcaaa gataacacct tttttgaaac
    24301 taaggttggt aactatgaac tgactcgcct tttggaaaaa gtgccaaaca gcggtgaagg
    24361 cttccaactc aaaatcatca ttaacaagga acttacaggg gctaaaatca atatcactga
    24421 caagtttggc cttcgtctag ttgatatttt caaatcagaa gaccaccata ttcatcagga
    24481 aaaattctac ttcctcatgg atagcttggt agaacgtggt gtctttacaa aatcggaaag
    24541 atagagccaa aatgtttgaa ctgacctata aggactgcta tcatgtagag cgtactctca
    24601 agtatgagga tcatgaggct ctcatgttga ctttgtcagg atgtgtaacc ttaccagata
    24661 cactttatgt gacttctctg acttttaggg gccaaaaagt ttatcagggt ctggtcggag
    24721 acctctaccg ttttctatct catgcagatt ttttacatca aaactaagat ttttcttagt
    24781 tttttcttat ttttgttgat tttttcacaa tgtttctata aaatagaaga atagaaaggt
    24841 tgtgattttg tgaaagataa acagtttgct attccaaaag ctacagcaaa aagactctct
    24901 ctctactatc gaatttttaa gagatttcat gcagaaaaga ttgaacgtgc caactctaag
    24961 caaattgcag aggccattgg gattgattca gcgaccgtac gtcgtgattt ttcctatttt
    25021 ggtgaacttg gtcgtcgtgg ttttggctat gatgtcaaaa aactaatgac attttttgcc
    25081 gatttgctca atgacaactc tattaccaat gtcatgctgg ttggtattgg aaatatgggc
    25141 catgcccttc tccactaccg cttccacgaa cgtaacaaga tgaagattat catggccttt
    25201 gacctagacg accatcctga agtcggtacc caaactcctg acgggattcc catttacggg
    25261 atttctcaga tcaaggataa aatcaaggat gctgatgtga agactgctat cctaactgtt
    25321 cccagcgtca agtcacaaga ggttgctaat ctcttggttg atgctggtgt gaaaggaatt
    25381 ctcagttttt caccagtcca tctgcattta ccaaaagacg tggtcgttca gtatgtcgat
    25441 ttgacaagtg aactccaaac cctcctctac ttcatgcgaa aagaggatta gaaagcgaaa
    25501 atcattttat gaaaaaacca gttattggga ttacaggaaa cgaaaaaact catccagatg
    25561 atgacatcat gatgagctac gcagcaaaag gctttgttga aggcgttaaa gatgctggag
    25621 ggattcccat catcctaccg attggtgatc aagaaatggc ctgccactat atcagtttga
    25681 ttgacaagct catcttgaca ggtgggcaaa atgtcgatcc aaaattctat ggcgaaccca
    25741 aaaccattga tagcgatgat tatcaccttc aaagagatat cttcgaactg gccctcatca
    25801 aggaagctat taaacagaaa aagcccattt tctctgtctg ccgtggtacc caactcttta
    25861 acgttgccat gggtggaact ttgtaccaag atatcgaaga ccattggcag gattcttctg
    25921 ttgagtacac aactcaacgc ttggtaacag aaccagatac cgttctccaa gaaatctatg
    25981 gagaaatctc tcatatcaac tccttccacc accagagcat caaggactta gcaccaaatt
    26041 taaaagttgt ggctcatgat cctaaagatg gtatcattga ggctgtcatg agtacggatg
    26101 atgtcgcctt tctcggtgtc caatggcatc cagaacttct ttttgaaaat cgtcccaaag
    26161 ataagaaact ctttgactat gtcgttaatg aactttagat taaatctgtc ttttcacgat
    26221 aactaaagta attagaatga gagacaatca aatggtccaa gagaacaatc cccatcagtt
    26281 cgcaggcttc tttaacaagt ttagtgacat gatcatcatt ttggctaggc gctaccgctc
    26341 ctgaaggatg attgtggacc aagataagag aagtcgccat atgcttgatt gcatagtgaa
    26401 gaatctctcg cggttcagcg atactacgag ttacagaacc gataaaaatg gtctgctgat
    26461 ggatgatttg attttgagta ttgagataga gtgccaccag gtgctcttgt tttttatccc
    26521 ctaattcctg ctgcatcttc ttggccaact tttgactgct gagaatactt tccatttcaa
    26581 gagtctcgtg tttgtgaata cgatgcccca gttcaatcat agcttgtaat tctatggcct
    26641 taacacgccc aataccagac aaactctgca attcctgcag ggtcattttt ttcaaatccg
    26701 ttaggcttga aagattgttt aagacttttt gggcaatttc aaaaacgcta gcttgacgtg
    26761 ttcctgtcct gagtaaaata gctagcaact cttggttact aagcgcttca actccttcct
    26821 tggccagcct ttctcttggt aatagtgaat cttcttggaa tgaaatactg tacataaaaa
    26881 tcctcctcac tttattattc gtgagaagga tggaaaatta gatttttttc tcaattggag
    26941 ccacactggc taaaagtttt ttcaaaccta cttctgggaa attgattttc aattcctgcc
    27001 tagcaccgct acctgaaact tccagaacgg ttccctctcc ccatttcttg tggagagcaa
    27061 tatcaccaat ggaccaattt gcctcgctag atgctggttt tgcgccagct gtaaattgac
    27121 caaatggaag accgcttgac tggattgatt ttggggcagc accgcgttta cggtcttgaa
    27181 gagcctgagc caaactcata ccttgaccaa aggaaatact accactgcta tatgatgcct
    27241 taaagcttgt atttgcagga cgagccagac cttgatactc aagcaagtct gaactgattt
    27301 cgttaataaa acgagtcgga cggttataat tggtacgacc aaaaagcaag cgtgagttgg
    27361 cattggtcag atagagaatt ttctctgcac gcgtgatacc tacataggct agacggcgct
    27421 cttcttctaa ttcatctgga tcttcagtcg cacgactaag tggaaagaca ttttcttcca
    27481 tcccaatcaa aaagacaact ggaaattcga gacctttggc agcatgcagg gtcatcaagg
    27541 tcacttctga tgtctcctga ctacctgaat ctgtgtcggc aatcaaagcc aagtcattta
    27601 agaaacgact cagtttgtcc agaccagttt cctcttttgt cacatcagtg gtgtcatcaa
    27661 agttcttcgt aacagaaaga aactcttcga tattttcaac ccgtgccttg ctttctagag
    27721 tcgcttgggc gttaagaata tcgatataac ctgttttttc taggacggac tcaaccaact
    27781 ctgtaatgct taagtggtct agctgctccc gcaaatcaag catcatattg gcaaaatccc
    27841 agatagattg ggctgcctta cccttgatac cagacaacat aatattagca gaagcatcca
    27901 gcatagacat attttgcaaa tttgcaaaat cacggatttt ctcaactgta cctagaccaa
    27961 ttccacgttt aggctcgttg ataatacgct caaaactaat gttgtcactc aaattagcaa
    28021 taaggttgag ataagcaata atatcgcgaa tttccttacg gctgtagaat ttcgttccgc
    28081 caaccatggt ataaggaatg ttagacttga gcagggcttc ctcaattgta cgggactggg
    28141 cattagtccg atagagaact gcaaaatcct tatgaaggaa gttttgactg cgactaagtt
    28201 catcgatggt tctggctaca aatacagcct catccagctc atcatcagca cgatagtaaa
    28261 cgatttgctc cccatcagcg ttttgagtcc agagattttt aggacggcga tttttattat
    28321 ttttaataac ctcgttggcc gcttggagaa tggttttggt tgagcggtaa ttttcctcca
    28381 acaaaacaac cttagctttg gggtaatcct tttcaaagtc caagatattc tgcatatcag
    28441 caccacgcca accgtagata gactggtccg catccccaac cacacagata tttttaaaac
    28501 gggaagccaa gagtttgacc aattggtact gagcgtggtt ggtatcttgg tactcatcaa
    28561 cgtggatgta ttggaatttt tgctggtagt aggtcaaaac atcaggattt tgatcaaaga
    28621 gacgcaaggt cagcataatc aaatcatcaa agtcaacgga ttcagactga cgaagttctt
    28681 tttgataggc tgtataacac tgggccacaa tttgcgtata catatcgcca gcttgggcag
    28741 cataagcaac atcatcaatc aaatcattct tagcattgga aatggtcccc aaaatagttc
    28801 gttcattcca ttttttagga tccaagttca actgtttgag aatacgtttc atgagcgttc
    28861 gctgttcacc aggatccaca attgtaaaat tacgattgta gccaatatgg tccgcatcgc
    28921 gacgcaaaat acgcacacac atggagtgga aggtcgcaat cagacagtcc tgagtagctg
    28981 gattgaggct ataagcacgc tctttcatct cacgcgcagc cttgttggta aaggtaatgg
    29041 ccaagatatt ccaaggattg accagctttt catcaatcaa ataagcgata cggtgggtta
    29101 aaacacgagt ctttccagaa ccagctcctg ccatgattag caagggacct tctgtcgttt
    29161 gcaccgcctc agcctgacgg tcattcattc catttaataa tgcgttcatc ttctcttcct
    29221 tactcttgaa gtcaatattt ctattatatc agaaatcagg gaaaatagaa actttacggg
    29281 gagtagcaaa atatagtgga ttgaaactag aatactacac tgtgggtttc taaaacactc
    29341 gacttttcac ccaatttttt cataaactag ctcaatagac ttcctgcaaa actagaatcc
    29401 tagttcatga ttgataatgc cagcaatcaa attcattcgt aatccgaagc gtttacgatg
    29461 atttcgatag attgttgaaa acattttaaa cgtttttact ttggcaaaga cgttctcgac
    29521 cttgcttctc tccttagata gcgcatggtt acaggcttta tcttcagcta ttagcggctt
    29581 gagtttgctg gatttacgtg gagtttgtgc ttgaggatat atcttcatgg gcccttgata
    29641 accactgtca gccaagattt taccagcttg tccgatattt ctgcgactca ttttgaacaa
    29701 cttcatatca tgacaatagt tcacagtgat atccaaagaa acaattctcc cttgacttgt
    29761 gacaatcgcc tgagccttca tagcgtgata tttcttttta cttccgtcac atcaatcatt
    29821 accgtgtcct cagaactgag aggagttctt gaaatcgtaa caccactttg aacaagagtt
    29881 acttcaaccc attagctccg acggataaag ttgctttcgt ggataccaaa aacagccgca
    29941 atttcttcat aagttcgata ttctaggctt aatttaggtt ttcgtccacc ttttgcgtgt
    30001 ttaagttgat aagctgtttt taatacagct aacatctctt taaaagtcgt gcgctgaaca
    30061 ccaacaagac gcttaaatcg tgtatcagtt aattgtttac ttgcttcatc attcatagaa
    30121 ctactatacc atattttgtt tcgcaggaag tataatataa aaaagtaaat ttaagattgg
    30181 caatacgaac gttaaataga attccatttc tctttttaga atcaaaacga caatattgtg
    30241 gaatctctac aggaacaata gactgcgaca ctaaaatatc ctcccttagt tttactttac
    30301 taatagtata taggaggaga gccctgaatc ctagaccctt tgttatgatg cgcttacaaa
    30361 cagagttgga aaaaatctta aaagcagaaa aacgcatgat atcagcccct aacacttgat
    30421 acaatgcatt ttattatgaa aagatctact ggatttttta tcaaaataaa cttccagtag
    30481 tcttttcact ttttattaat aagttccttc ttcaccttgg ctagtcaaga taacaggtcc
    30541 atctttcgta atgacaaatt ggtgttcata ctgacatgac aatccaccgt caatggtctt
    30601 atgcgcccaa ccagttttca tatctgtatc aatttcccaa tcgcctgtat tgatcattgg
    30661 ttcaatggtt aagaccattc cttcacgaag acggagtcca cgacctgcaa taccatagtt
    30721 aggaaccatt ggttcttcgt gcatagttgg gccaacacca tgaccaacca aatcacgcac
    30781 tacaccgtaa ccacgacttt cagcgtattc ttgaatagcc gcaccgatat caccgatacg
    30841 atttccaaca acagcttgct caataccctt gtacatagct tctttggtta catccatcaa
    30901 gtttttgact tcttcggacg gtgtaccaac agcataagcc caacatgagt ctgctaaacc
    30961 accagaatag ctctgagtgt attttttcat ttgttcaaca ttgttgaagt ttaattttga
    31021 gacattcagg tcggatttag caatgggacc tcccaaaacc atatcaactt tgagcaaatc
    31081 accatctttc aagatataat gacgagggaa agcgtgagcc acttcatcgt taagagagca
    31141 acaggtagca taaggatagt ccatcatggc accgtcaacc ccaatctgaa gtggaaggaa
    31201 attttcttct ttacaacgac ggcggacata ttcttcaact tcccacatat ctacgcctgg
    31261 tttaatcaaa tcacgtaagc ctatatgaat acttgctaga aaatcaccag ccttgtccat
    31321 agcttcgatt tcacgagctg attttaatgt tatcatcttt tctcctagtt tctaattaat
    31381 tttaacagtc acatttgctt ttgaaacaat ctggtgacca tgataaatat cgtaatcaat
    31441 tatagctgac cgtctcgtat gatgaataat ccgtgcctga atgcgcaata tatcatctat
    31501 ctgaacagcc tgcaaaaagt agatcagcat ctgctcgata atgagattgc gaccactatt
    31561 aacaactaaa tcttgggtca tgtgggtcag aatttctgcc aatacaccat tagccaaaac
    31621 tccatttttt tctagcataa agggttccac tgtaatgact acttcatcat ggtgataaga
    31681 gagcttttgt ccaatctgct cagaaaaagt tggtagagcc gaaacttggg aacggctcat
    31741 cttctccatg acatctcgtc gcgtcacaac gccaagcaaa gtttgattgc ttcgaacaac
    31801 tggtaccatt tcaaagtctt ctgcgatcat ccgttgactc acattggcaa tatttgtcga
    31861 taatccaacc aaaaatagac tacgagacat aaccttatca attgtcgtgc ttggtgattt
    31921 atcaccagcg tctctcatgg ttacaacgcc aacaacgacc tgatgttgat tgataacagg
    31981 gaaacggctg ctacgattct tacgaaccaa gtccaaataa tctttaactg tatctgtctc
    32041 tctcagaaaa ccatactcat gactagggcg ataaagtttc tcaactgtca gaatatcagt
    32101 cttgatttgg acatttgaca aggctttatt gatcgtggtc gcgacggtaa aggtatcatg
    32161 cttacttctt agaacaggaa tccctttttg attggccagt ttaagcacat catcatgaac
    32221 ctgaaatccc cctgtaacca gaactgcatt ttcattttcc aaggctagca actgaatacg
    32281 ggttcggtct ccgacaatca agagcccccc atcatgaagg taagacaaga tattttgttc
    32341 agtcatggca ccaattgaaa acttgctaaa ttctctctct aaaccttctt gcccagccag
    32401 aacctcagaa gaagtcactt ctgcaatttc agcaaacgtt aatctctcta tagcaacttt
    32461 ctgggattta acacgaattg ttccacttct aggacgggtc tccacaattc cacggttttc
    32521 agcttcttta atagcccgat aggctgttcc atcactaact cctagatgat tcgaaatgct
    32581 acgaacactg acccttttac ctactggtaa ttcctccaaa tagcttagaa tttcctgatg
    32641 cttactcatt gaactctcct tttacatacc gaaattcaag ataatcccgc atttttcttg
    32701 tgtaacgatc acttccctta aactgacgga acaaactaaa tccagactta agagcaactc
    32761 tttggctagc ttcattttca aggtgggtaa tgatagataa ttgttttaag ccaaattcct
    32821 caaaagaaag ctgacaaatt tttctaacaa cctctgtcat aaatccttgc gcccaagcat
    32881 cttttctcaa aaaatagcca agctcagctt cttttttgat ttcatctaac ttctcaaatt
    32941 taatagaacc aatcatttgt tgatttttct ggtcacaaat tgcccacact cccaaagggg
    33001 acttcataaa gtaattggcc agtgcatatt gactttcttc cagacttgcc tgcgttggga
    33061 aaataaattg aagattttct ggatttgaag ctatctcgcg gaagtcctga ctatcactaa
    33121 aaaagaaagg acgcaaatac aagcgatccg tttcaaaaaa agaaaacatt gctaatttgg
    33181 tccaaatatt cataaacacc tctacggttt aatcctcaac aagtctaata tccgctccta
    33241 aattacgtaa tttttcgata atatcagaat aaccacgtaa gataaactcg atattggtaa
    33301 tttcagtttt accttcagcc ataagcccag caatgactag tgcagcccca gctcttaagt
    33361 cggtcgcttt aacactggcc ccacgtaaat cacgtccacc cgtgtacaaa atatgaccat
    33421 ttgttgtcga aatatccgca tccatctttg ctagttcaaa aacatgattt acacgttttt
    33481 cgtaaatcgt atcgacaatt gtaccacgac cattcgctct tagtaaaaga ggggtaagcg
    33541 gttgttgcaa atcagttgca aagcctgggt aaggagctgt cttaatattg attgctttca
    33601 aattagactg ttcctcgaca aaaatgctgt cttcagatac agtcattctc actcccattt
    33661 cttccaactt agcaataaac ccttccaggt gttcgtaaag aacattattt atacgaattc
    33721 ctttaccaac tgcagcagct aaagatatat atgttccagc ttcaatgcgg tctggaatca
    33781 cctgatgacg tgtcccatgt aatctttcaa caccatcaat aatgatgata ttagttcctg
    33841 ccccacggat atgggcaccc atattattca agagagtagc tacatcaata atctcaggtt
    33901 cacgggctgc attttcaata atagtacgac catttgcttt aaccgcagca atcatcgtat
    33961 taatcgttgc tcccacacta accgtatcca tgtaaatact tgcaccatga agtcctgtat
    34021 ctttagcaga taacttcatg ttatctccct cgtagctagc agtggcaccc atagcttcaa
    34081 acgccttaag gtgtaagtca atcggacgag gaccaagatc acatcctccc ggtagaccaa
    34141 ctgtcgcttc accaaaacgg cctaagaggc tcccataaaa ataataagat gcacgaagac
    34201 tgttaatttt accataaggc attggaatat tttgaacacc tcttggatca atctccaaga
    34261 catcgtcata acgcttaaca gtagctccca tcaattccat gatttcgaca agactggcta
    34321 catccgaaat atctggaaca caatccaaag tcaccacatc atcagccaat ataatagctg
    34381 gaattaaggc cacaacacta tttttagcac cactaatagt aatttcacct tgcagtggta
    34441 atccaccatt gataacaatt tttctcattc taagttttca atactctttc aagatttcta
    34501 ataaggtctt caaaataaag tatatcataa atttatcctt ttttccatcc ttttcaattt
    34561 tattggataa atcagagttg acgagttagt aactgaatta ctaatactca ataaaaatca
    34621 aagatcaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgag gttgtagatg
    34681 gaactgacgt agtcagtatc ctacacgtac ggcaaggcga tattgacgtg atttgaagag
    34741 attttcgaag agtataatct ttctcgaatc gctattgccc cttttttatc ccctgaaacc
    34801 gagtaggagc taagactaga tctcttatct aaatatcgga atacggctgt tcaactaaat
    34861 tttagcaaga acctctcccc cttctctcag ttcacagaag cgttttatac ataccgtcct
    34921 atatttcatg aacaagacgt tttcaggcta gcatcctatc agacaatcta ttttaaagat
    34981 aaccgtgact caggatcact tctatctgtc gttttctctt tatagtgata gacctcacgg
    35041 gataagtcgt acatctttcc tcgtgtatac aagatatgag gacgttaaaa ggttacagtg
    35101 aaaatagaaa atcttagtac gaattcaatt actctcgtga tttacgcata taggttacga
    35161 ctaccttttt ggactttaga gtttgaggcc ctcttatccg ctatatacgc cttattatca
    35221 cgttcctgtt cgtagagcca cgatttcgct atcccttctt ctgacaattc ttatttccag
    35281 cgtcagactt aaaacggtct atccccagac cattttaatc cgctacctca cgatagtcag
    35341 gcttgggaat cgctatttga ctcgccgaga actttgacat cagatatact ataacaaatt
    35401 gaaataagaa tcaaacaatt taattttgaa attcaaatca atttataaca atattttaga
    35461 agatatgctg tgctattcca gattcagttc gctatacatg cccgtcgtac cacaaaatcc
    35521 cgtgtctgat gaggcacggg attttttagc ttctttactg agatggattt tcctttttag
    35581 ttcgtgccaa tctcaaggca cgatttggat ttagacgatt aaatagttct tccaatttct
    35641 tttcattcca aacgtctgcg gcggaaacaa aattaccatc cgcatctcgg aaagatatcg
    35701 gtttatctcc cataccagtc tcctagtcta caaattcaaa ctcaaattta ccaatgcgga
    35761 ccaaatcccc atctttagct ccacgcgcac gaagggcttc atcaaccccc ataccacgaa
    35821 gctgacgggc aaatttcatg acagattcat cacgatcaaa gttggtcata ttaaagagtt
    35881 tcatgagttt ttcaccagaa agtacccatg tcgcatcgtc atcacgacta atttcaaagg
    35941 ctttttcttc ttcgtcaaat ccatagtaag cttcttcttc catatcggac tcgtcgtaga
    36001 gcaaaaattc tggtgtctta tctaacaatt cagctgtagc atctaaaagt gttgccagac
    36061 cttgcttggt caatccagaa attgggaaga tagctggtaa ctcttcaaat tcatcataat
    36121 tttcagccaa ttttttctta aattcttcaa gattttcctg actctcaggc atgtccatct
    36181 tattagctac aataatctgt ggacgctcca tgaggcgaag attgtaagac tccagctctt
    36241 tattgatagc taggtaatcc tcatatggat cacggccttc gctagctgac atatcaatga
    36301 tgtgaaggat aacacgtgta cgctcgatgt gacggaggaa ctgagttccc aaaccaacac
    36361 cttgactagc cccttcaatc aaacctggca agtcggctac tgcaaaggat tcacctgatt
    36421 gggtgcgaac catacctaaa tttggtacaa tagtggtaaa gtggtaggca ccaattttag
    36481 gcttagctga ggtaataaca cttaaaagtg ttgacttccc tacagatggg aatcctacta
    36541 aaccgacatc tgccaagatt tttagttcca attgtaactc acgttcctga cctggttctc
    36601 cattttcaga gatttccggt gcaggatttt ttggtgtcgc gaaacgaata tttccacgtc
    36661 caccacgacc accgtgggca acgataaatt cttgcccatg ttcaatcaaa tctgttaaaa
    36721 ccttgccagt ctccgcatca cgaacagtcg taccttgtgg tactcgaact ctaaggtcct
    36781 cagcaccacg accatgcatc cctttggtca tccctttttc accagaatca gccttgaaat
    36841 gacgattgta gcggaaatcc atcaaggtac gtagtccttc gtctacaacg aagaccacat
    36901 tgcctccacg accaccatca ccaccccaag ggcctccatt agggacatat ttttcacgac
    36961 gaaaggcaac cataccatcg ccaccattac cagccttgac cttaatctta gctgtatcta
    37021 aaaacatact cattatttct tctcacttta aaaaagggct gggaaatccc agtcactaaa
    37081 ttttcttgaa tctattttat agattactga gggcaccaat tgcagttgca aaaattccca
    37141 ataaacttgc tactagcatg ataatcacga taaacaaggt tattttctca aacatagttt
    37201 ttttacgatt tccattatct ccaaatgcca tttttctctc cttcgttaca ttctattttc
    37261 tattatctta gcatgaattg agctagtttt caatagtcag ttgctactgg tgcgataatc
    37321 cataaaataa tgtaagctac aattccagct ccgtaacagc aagtaagaac accccaaatg
    37381 acttgaacga tagtcggatc catatccaga taatgggcca ccccagcaca aacacccgca
    37441 atctttttat cacgaccgct tctcattaat tgtttttttc atagctgttc ctctttctat
    37501 tcttcatggt ctttccaata gtctctcata ctgatcaact gtgtttttga agccttcaac
    37561 atgcgtctag atccttttac aggtacagca accacctgtt gctgaagata caaaactgtc
    37621 ttaaagatac gctgactgac cgtatcatct ttagccaaat ctttctggaa gttatttgaa
    37681 ataatggcat ccagataaaa ctcatgcact cgtttcccaa agttctcagc tgaaatctca
    37741 tacaatttct ctgataaggt atgctcgttc atgtctggtg ttgcaatcag ggcttccaaa
    37801 atagcaccag ccaaatcatg ttctccatag tacaaggttc caaacatttt atcactgatg
    37861 aggttgttca aataaggatt tccgtgagca atgacaggtg ttccactggc taagctttcc
    37921 aagtaggtca aaccttgcgt ttcgcttgtc gatgccgaaa tgaagaaatc cgccgcttta
    37981 tagtaaagag ccgtctcact aggagcaatc atccctgtaa agatgactga gtcttgaatc
    38041 tctaggttct gggcttgctc tttgaggtca ttcagataag ggccatcccc agctactacc
    38101 agtttaacct tgtcttcctc tttcagaaca tcagcaaagg ctgctaaaac tgcttgaata
    38161 tttttttcat aggagattct cgaaagacta agcaacgtct tttcaccatc ttgaatccct
    38221 agtttactac gcagttcttt caaattttcc tgcttgattt ccggacgctc aaacttggct
    38281 aattcaatcc cagtaggaat gacccgtttt tcaaccttga ccttataatc agatagcaag
    38341 tcacggacaa tctcactagg acaaataacc ccatccacat catgcaggaa acctctaacc
    38401 agatacttga ccatactcgg ccggatcaac atccccttag caatataatg gacatagtct
    38461 tcatactggg tgtgataggt atggatgact ggaattttca attcacgcgc aatccaaatc
    38521 cccaacaggc caagagaaaa ttctgtctga gtatggataa tatctagctg atactgttta
    38581 gcaatttcaa gtgccttgct aaaacctcgg taggcaaagc gacgatcctt aaaagcaaag
    38641 aaaggaacac ttggaatgcg gataatttgc caatcttcgt agcgattgac atccttatct
    38701 gtcgtcgtaa agataaaaac agcatgtccc tgcttttcaa gttctgtttt caaggttcga
    38761 atactggtcg caacaccaga aacttgagga aaataggtat ctgtaaataa accaattcgc
    38821 atagattacc tcacttttta ctttctccct aaagcggctt gtttctcata aaagtccaac
    38881 cagatttgta acagatgctc ttcagaatac tctctggaaa tattcttagc cttttctttg
    38941 agatctttta aggcagcagg atttgcttga tattccaaaa tagcctcttt catctcttct
    39001 ctacccgctg tcgcccgata atttccctcc aaaatcacct tatagagatc taaatcacgc
    39061 aacataatag gagcctcaca actcgcagct tctaaaatag tcataggaaa gagctcattg
    39121 taactaggca acaagaaaag atccgctaga gcatacaatt cgcgcatccg ctctggcgat
    39181 acaatgcctg gaaaaatcaa atttttaggg ggattttcca taattttctt atagtgttca
    39241 taaccatctg tcataccacc aaaagagaag ccaccagccc agataaaggt aatctgaggc
    39301 aattcctcag ccagacggat aaagtcatca atccctttac gtttctgaac ttgcccagca
    39361 cctactacga taaactgatt gtcactaaga ccaagatctg tgcgcagtct gactacctct
    39421 tcttgtggta gaggatgcca tttttccttg ttgacaaagt taggaatata ggtcactttt
    39481 tcacgtggaa taccagctgc taccaaatcc tcaataaaca taggattgac cacaaccaag
    39541 tgctccatcc ggttgtaaaa agaaaataca tagcgtttca caattccctt taagaaaaat
    39601 ggaattttca aacttccctc aagtgtagct ggcaagaaat gcacatagcc aatctttctc
    39661 cctgagcgtt tcttttggaa ggttgataaa taatagggaa aatcaatcgt atgaaagtga
    39721 gtcacatctg cctcgattgg aagattttct gtaacaatca attggtcctt ggcagcacgg
    39781 tgaagaagac gaactaattc acggtaagca cctgaaactc cctgtcctgc tactttctca
    39841 cttgaactca acatattgat gcgtaatttc tttttctcca taactactat tatatcattt
    39901 tctttgaata aaatcagcaa aagaaaggag agactagagg aaaagagggg aaatttcctc
    39961 gcttttccaa cagtctctca catgctttta tatgtttact taatgcctag ggcaatgcgg
    40021 gcatagcgac tcattttttc aactgtccag gctggatacc agactaattt aacctcagta
    40081 tccgttactt ctggaacctc tatcatagca tcataaatct ggtctgtcaa aaggtctgct
    40141 aagggacaac ccatagttgt caaagtcatg tcaatctctg tttgccctgt gtcaccgtca
    40201 aaacgaatct catagatcaa accaagattg acaatatcga ttcccaactc agggtcgatg
    40261 acttcttcca aggctgttaa aatccgtgtt ttgatgtttt caatttgctc ttctgtataa
    40321 gccatatttt cctcactctt agtcttcaat aaaatcacga agcggtttgc tacgacttgg
    40381 ttggcgtagt tttctcaaag cctttgcttc aatctgacgg atacgctcac gagttacgtt
    40441 aaagactttc cccacatctt caagtgtgcg catttttcca tcatctagtc caaaacgtag
    40501 acgcagaaca ttttcttcac ggtctgtaag agtatctaag atttcatcca attgctcacg
    40561 caagacgata cgagtcgtat aatccactgg attttcaatc acttcatctt cgataaagtc
    40621 tccaaggtgg ctatcgtcct cttcaccgat aggagtttca agagatactg gttcttgggc
    40681 aatcttcaag atttcacgaa ccttatcagg tgtcatatcc attcgttcag caatctgttc
    40741 tggtgtcgga tcttgcccca attcttgaag gagattccgc tgttcacgaa ccaatttatt
    40801 gatagtttca accatgtgaa ctgggatacg gatggtacga gcttggtccg caatagcacg
    40861 agtgatagcc tgacgaatcc accaagttgc ataagttgaa aacttgaacc ctttagaata
    40921 gtcaaacttg tcaaccgcct tcatcaagcc catatttcct tcttgaatca agtcaaggaa
    40981 ctgcatgcca cgaccgacat agcgtttggc aatggaaaca accaaacgaa gattggcttc
    41041 cgcaagacgt tgtttggctt cgatatcacc agcttcaaca gccagtgcca actctttctc
    41101 ctcttcattg gtcaagagag gaacgacccc tatttctttc aagtacatac ggacagggtc
    41161 attgacctta gcagaagttg acccaatcaa gtcctcatcg ctgagttctg gttcttcttc
    41221 attgctaaga acacgcgcac ttggatttcc ttcgttatct gtgatagaaa tgcctgcatc
    41281 ctgaatccgt tgcaagagat cttcaatccc atcagcgtcc aaggtaaaag gaataaccag
    41341 acttgcattg atttcatcat ctgttgctgt ccctttttgc ttatgattac ggataaattc
    41401 tgctacctgt acgtcaaatg ttgttacttc tttttgtttt gttgccatta ttactccatt
    41461 cttctctttt gggaaattaa acgttccaat tcttctaggg ctgtatctgt atctcctaca
    41521 tggctagctt cctgcacctt ctttttgatt ctcatattgt cctgattcaa gagagccttg
    41581 tttcgagtca tctctacttc actaagttcc tgcggcgata tctcagcagg caaatcctga
    41641 gctaaaactt ggtaccaagc tctttcaact tcctctgtct gctctgctaa aacttctgga
    41701 ggaagatttc catactggcc aagcaagtca tataagacct gaaattcagg tgtagcaaat
    41761 gcaaagtctt ctcgcaaacg gtaatcgttc aaaacaagag gggattccat catccgatag
    41821 agtagatggg cttctgccct cataatagcc gataactgct tggtgacagg catggtgatt
    41881 ggcgtcggtc tggaaattct ttccatgcga ttctgccttt gcacctgacg actctcatta
    41941 acaatctgct caatctgggt ataatcaaag gacgccagac tgtcagctaa aatatgaata
    42001 tagctgtttt gagcagcgat ggacttttct tgaacaatca agggagctat tttttcaata
    42061 aactcaatct gagcctgcag attttcactg ttttcaggtt tgtactgatg aatgtagaac
    42121 tcaatcggac taatacgagt ttttgttaat agataggcca agtcttctgg accatttttt
    42181 tgtagatact catcaggatc caagttatca ggcatactaa cgatttgcac aggcatatca
    42241 ccaatttcat ccaatgcttt caatatcgcg gcttgcccag ccttatctcc atcgtaaaca
    42301 agaaccaatt tcttggttaa ccttttcaga tgctcaacat gctctcgact caaggccgtt
    42361 cccatcgacg ccacagcatt ttcgattcca gcccgatagg ctgcaataac atccatgaat
    42421 ccttccatca ggtaaatctc actagttttt ccagaagatt tttttgccct atccatatga
    42481 tataattcgt aacttttgtt aaaaattgca gtcgatcggc tgtttttata cttagaagtt
    42541 tgtgaatccg ttttttgcca gatacgacct gagaaggcaa tgacctttcc ttggtcattt
    42601 gtcaggggaa acataatgcg attgtgaaag gtgtctacaa attgattgtc atccgagaga
    42661 taaaacaggc ctgaatccag taaatcctct tcacgatact gatcagacaa acgttgatag
    42721 agatagtttc gttctgaagg tgctaaacca atccaaaaat gtttaagcac ttcatctgtc
    42781 aaaccccgct gataaaggta atttctggcc tcttcgccca tagtcgttgt catgagaata
    42841 gcatggtaaa atttagccgc atcttcgtgc atatcataaa gatcttggta aggcgaggct
    42901 ggcttctgtt cactataaag cggtttttca acctcaatcc cgacacgctg acctaagatt
    42961 tggacagcct ccataaaggg aaccccttgg tactcctcga tgaatttaaa gacatcacct
    43021 gagcgaccac aaccaaaaca gtggtaaaac tgcttgtcct ctacaacgtt gaaagaaggt
    43081 gttttttcac catgaaaagg acagagccct agatagttcc gtcctgcctt ttgtaaagaa
    43141 atcacatctc ctatgacttc cacaatgttg gcattgtttt tgatttcttc aatgacttgt
    43201 ttgtcaacca tacacaatac ctccatgtta tcatagttta ctttatatag tatactttat
    43261 ttcagaaaaa aagtaaacca tttcactcat tttccctact ttattcaaag agttgataat
    43321 aatcagagat tttcattttt gctttttctt cttggtttaa atcttggata atccgtcctt
    43381 ctttcatgac aatcaagcga ttgccgtatt tgagagcatc ttccatatga tgagtaatca
    43441 taagggctgt tagctgatct ttcttaacaa attcatctgt caattccatc aaagcaacac
    43501 tagtctttgg atccagggca gcagtatgct catctaacag gagtaattca ggtcgcttca
    43561 aggttgccat caagagactc aaagcctgtc tttgtccacc tgataagaac tcaatcggtg
    43621 tattcaagtg tttctcaaga ccatttccta ctttttcaat ggttacctga aattcatcct
    43681 tatagctagt caagcgtcgt ggtaacaatc cacgcttttc accacgaaac ttggcgatta
    43741 aaagattttc agcgaccgtc atacggggag ctgtccccat ctttggatct tggaagacac
    43801 gagacaggta cttggcacgc ttctcgggtg aaaacttagt gagatcttca cctaaaatac
    43861 ggatagttcc actagttagt gataaggtcc ctgctatagt gttaaagagg gttgattttc
    43921 cagcaccatt tccgcccaaa atcgtgataa agtcccgttc aaaaatttct aaggaaacat
    43981 catttaaaat aatcttttct tcatcaaagc catttttaac gattttggtt gcatttttta
    44041 attctacaat tgctgtcatt tgcttaactt ggctcctttc aagattgttt gcttaaatgt
    44101 tggaatcatg aggcagactg ctaaaatcaa ggcactgtat aaacgaaggt aacttgtatt
    44161 aaagccaagt gcgataactg cccacactaa aaattgataa gcgatagaac ctacaacgat
    44221 agtaaccaaa cgctctgcca agctcaaact cttgaaaata acttctccaa taatcaaact
    44281 tgcaagcccc acaacgataa ccccgatccc tcgagacaca tcggcataac cttcttgctg
    44341 agcaatgagg gcacctgcaa gggcaatcac accatttgat aagaccaagc ccatgagctc
    44401 catgcgtcca gtatgaatcc cgaaacttct agccatatca ggattatccc ctgtagcaat
    44461 ataggcttgt ccgagtttag tgtccaagaa aaagagcatg agagcaataa caatactcac
    44521 aaagatgaga cctgtcaaga gttgattcaa atccgaatca aaaggcaaaa catcctgaat
    44581 ttgcttggtt ccaagcaggc ctaaattcgc acgtcccata atcaagagca tgattgagtg
    44641 acaagaagtc atcaccaaaa tccctgagag caaggttggg atcttccctt ttgtataaag
    44701 aaggcctgct gccattccag ccaaacaacc tgcccctaca gcaacaagtg tcgctaaaaa
    44761 tgggttcacg cctttggtta tcaaagtgac agcaacagct cccccaagag ggaaggaacc
    44821 ttctgtcgtc atatctggaa agtttaaaat cctaaatgtc ataaagattc ccagacctag
    44881 aatagcccag acaaatcctt gagaaataat ggaaacaatc atattttatt taatcctttc
    44941 tatattcatc tttttaaaaa atgggaagag tctcctcctc cctaccttat ttattcgatg
    45001 acttgtcctg cttctttgag aacagactca ggaatagtaa tacctagttc ttgtgctatt
    45061 tttttattga tgactgactt accagttgaa aagacattga ctggggtatc ggctggtttt
    45121 gcacctttca agacttgcac aatcatttta cctgttgcca caccaaggtc atgttggtca
    45181 attacaactg atgccaaacc acctacttct accatagctg tcgcactggg ataaattggt
    45241 ttcttagaac tttgattgct agagacaacc gttggaaatc ctgatgcaat ggtgttatca
    45301 attggaaccc aaatagcatc taccttgcta gtcataacag tgacagttga ggcaatttca
    45361 tttgttgaag gaactgcaaa tgtttccact gtcagacctg ctttttcagc ataagcctta
    45421 aattcttcga cctgtgtttt tgaattgtct tcgctacttg agtaaagagc tccgattgtt
    45481 ttcacattcg gtgtcagagc cttgatgagt tcaacttgtt gttgagctgg attgtggtca
    45541 gatacccctg taatgttgcc acctggtttt ttcaaatctt taaccaagtt agcaccaatt
    45601 gggtctgtaa tagcggccat gataaccggt aggtcttttg ttgcactagc caacccttgg
    45661 gctgctggtg ttgcgatacc aaccacaagg tcattcccat ttgcaaccaa ttgtttactc
    45721 attgtcgcaa ccttactttg gtcaccttct gagttcataa aatcaatttt aacttgatca
    45781 tctttatatc cttcttctgc aagtccatct tggatccctt tataaatcaa atcaagggat
    45841 ggatggctca caaattgaag cacaccaatc ttagttattt tcttctcatc cttattattc
    45901 tgagcttctg atttattcat tgaagaataa atcaagcttc ctgctactaa gactgctaat
    45961 gcagcaataa ttccaattaa acgtttattt ttcattctgt ttctcctttt tatttccttt
    46021 aacatatttc acttatctaa acaagcgacg ccatcgtttt ctttccatac taacctccat
    46081 caaaaaaatc ctcacacaaa aaacttgtgt gaggacgtcg atgcgcggta ccacctcaat
    46141 tatagggaat ttccctatcg ctcagtctcg caataacgag atgcactgta aggtgtgctt
    46201 accgaatttt tataatttca aattctaaat agcattcagc ccaattttca tcatcgccac
    46261 ttatctgttt tcagctacca cagactctct aaaaagtttg tatgattact tttctgaatg
    46321 gttaaattat atcattttta aactacttgt caatagtcta ttagaatttt tttgatattc
    46381 acttttagca ttcactcttg aaaattatca acctgaatta cgcaatcctg tcgcaattcc
    46441 gttgatggtg atatgaatca atcgttcttg atcactagac aattctccac gacgttggcg
    46501 tttaatcaac tccaactgaa tatagttgag aatattaaag taaggcatac ggtaatccag
    46561 actagctttt agatatggat tgtcagctaa gagttcgtca tgtccttcaa tagccaagat
    46621 aacgttctta gtaacttgcc attcatttaa aatagtctca tagatggcct taacttgctc
    46681 gtcttcacaa agtttagcat attcaaaagc aatattcata tttgattttg acaaaaccat
    46741 atcaacattt gaaagaagcg attggaagaa aggccaattt tggtacatat ctcgtaagat
    46801 agcaatattc tctggatttt tattgataaa ttccttgaag cttgaaccaa ccccgtacca
    46861 tccagggaac ataacacgac tctgtgacca tgagaatacc caagggatgg cacgcaatcc
    46921 accgatttca gtaatagtct tacgagcggc tggacgagaa ccaatattaa aacttgaaat
    46981 agccttgatt ggacttgact cgaagaaata atcatagaaa tgctcattac caaagaccaa
    47041 atcacggtag acgtcgtaac tacggtccac tacttgatcc ataatggctt cataacgatt
    47101 tggggtattg gtatcgctct tcttctgagt aatcatacgg ttaatagctg ccgatactag
    47161 catttcaagg ttatagtaag cggcgtcttt gttaccgtat ttattcccaa ttacttcacc
    47221 ctgctccgtc aagcggatac gatccttgat agacttgagc ggttgagatg taatggcttc
    47281 ataggttggc ccaccaccac gaccgacagt accaccacga ccatggaaga aggtaacctt
    47341 aacgccaaat tcatctccaa tagcagtcaa ttgttgttga gccttgtaga gggtccaaca
    47401 tgatgacaag taaccgccat ctttattact gtcagagtag ccaagcatga tttcttggta
    47461 gttatttcgt gagtcaatcc attttttggc aaggctaaga gaaagatatt ttctcattgt
    47521 ttcctctgaa tgatccaagt cttcaattgt ttcaaaaagg ggaacaatct gaacacgcgc
    47581 cctttccgta tccaccagtc ctacttcttt taacagaata gctaattcta gcatatcaga
    47641 aaggctggtt gcatgtgaaa tgatggtctg acggatgaca tcatctccca acttatcttt
    47701 caaaacacga gccgtcttaa aaatagctag ttcttttgct aataattctg atttttctgc
    47761 gtgagtcgca gaaagaattc ggggatcttc ttctaattct ttcaagagaa ggtcacactt
    47821 ttcttcttcg ctcaactcgc tataacgaga atgaattcct gctgatttca agagttctgc
    47881 cacacaggct tcatagacgc tagagtcttg tcgcatatca attgatgcta ggtaaaaacc
    47941 aaatatctct actgcctgca ataattccac aaaatcacct gaaatcaagg actcgccctt
    48001 attttctagt agagaatctc gaatggcaat caaatccttg tagaaatcat tggcggtttc
    48061 ataacgagtc ccaacttctt catcctcaat cagataggtt ttagttgcct gaatttttga
    48121 ttgaatatca aacaaggcac gacggtaaag ctctttttcg cggtaaatcg agttatcctt
    48181 ggattgacga gccatttctc tgacttgctt gctgacgttg acaatgctag ttgaaagaga
    48241 aaattcacga taaagttggt aaatcttttt atcataatag ttcatgatga cttcacattg
    48301 agtgagtgca gactgcttca aggtctctgc tgtaacaaat ggatttccat cacggtcacc
    48361 acctatccac atacccatgg tgattggttt agcctgtttt aaattcagac catgcgcttg
    48421 cgctaagcgc ttatactccg tcgtcaaatg aggtacagct ttcaaaaagg agctgttata
    48481 atattccata gcattcgtga tttcgttagt cacttttaat tttttctcac gaatcatgtc
    48541 tgtctgcatg ataatttcga tgtaacgacg caaatcattg taccatttat ctttattgat
    48601 caaccccaac ttaacatcac ggtatttacg caaaagacta tgaatatgat ttgttaaatc
    48661 caacatactt ttgcgttgca cttgtgttgg atgggctgtc aaaacaggga caacattcaa
    48721 gtgttctagg atctcaacgg cattttcctt ttctgctacc aatttaatcg ttgtagataa
    48781 tttacctaaa tagtcctgat caatattatt ttgatgattg atttcataag ctaaatccac
    48841 atcctctgaa atattaatca aaagaggtaa gatagagaaa tagcgtgaaa tatagaccat
    48901 ttcatcattt gataagctag tcactagacg gtttagacct tgataatctt cctgcgttga
    48961 taattctttc aactgtatta ttttttcaaa ggtctctggg gcaagcatat ttttagtaat
    49021 atcttccagt aattctgtta gaatcaagac ttcttcttgc acaacacttt tattactata
    49081 attttctaat ttttgaagag acataaacta tcctttcttt atcctacttc aacagaaggt
    49141 tcattggttg attttccaat tctcggtaca acttagcgcg tttttcactg gcatcaatat
    49201 ttaagacaaa ggctactgcc actgataaga ctagaagact atttccaccc tgggataaga
    49261 aagggaaagt cactcctgta gatggaatca agcccgaaat ccctccgata ttgacaaata
    49321 cctgaaccaa catcatccct ccgacaccga gtgcaaccat ggcattgaaa ggattctccg
    49381 ctcggatacc gaccaagata atccgcaaaa tcatgaaaaa caagagagct aaaataagac
    49441 tggcaccaac aaagccaaat tcttcaatca cgatagaaaa gacaaagtct gtatgagctt
    49501 ctggcaaata acctcgtttt tcaatcgagt ttccaagacc tagaccaaac caaccaccat
    49561 tgaccatggc aaaataagaa ttagctaact ggtgacctgc atcagcacga tcggcaaaag
    49621 gattaaaaaa ggcactaaag cgcttggcta catagccaaa tactggaatt tttgaaaagg
    49681 tctcaacacc gattaggctg atagtggtca agacaaagac agaagtggca gatacgagcg
    49741 ccagaatggt tgaaaaccag cgataagcga ttccactaac tgtatacata atcaaggaaa
    49801 ccaagactaa aatagtcgca tttcctaaat cagggaaaat tcccaaactt ccaatcagaa
    49861 ctaggagaac gaatcgccaa tcattaaaag cacggggaag ccattgattt tgagtcaaaa
    49921 cttgaaaatc ataagtagct atttcttctt gctgtttgga gaatcggtga gctaaatacc
    49981 aaataataat gatttttaag tactcagctg gctgaatagt tactcctgca accgaaatcc
    50041 aaccgtatgc cccgtttacg gaaataccaa taaaacgagc caagaacaat aaaagcattt
    50101 ctattaatat aactaaaatg attagtcgct catttctcaa aaaatctagt ctcaatttat
    50161 aaattaaggc aatcagtatc aaactaacaa tccaaaagat tccttggttt cgaaccaact
    50221 gcaaggcgct cttgccttct tcaattaaaa tagcactggt ggtcgaatag accacaatca
    50281 agcccaaaat agataaaagc aagtagggaa tcaagatgga ataatttaat aagtgcctct
    50341 tactaatctt catagtatca ccactctact aggatacaga caaatctgtt ccaaattccg
    50401 ttttattttc tagttttgat tgctattata ccattttttc agaaagaaaa aaactcttac
    50461 cttacaatcc ttcgaatttt actgtttttc ataattaggg cagaatttga aatcgtaaaa
    50521 ccattttgaa caagagttac ttcaacccat tggctccgac taattatgtt gctttcgtga
    50581 atgccaaaat cagccgcaat ttgttcataa gtgggctatt ctcgcatgta ttgaatagtt
    50641 accatgagga gatcgtctag gcttaatttg gtttttcgtc caccttttgc gcgtttacgt
    50701 tgcgttgata agctgttttt aacacagcta acatctcgtg cgctgaacac ctacaaggct
    50761 cttgaaacgg ctatcgctta attgtttact tgcttcatca tccatagttt tattgtattg
    50821 tatttttgtt tcgcaggaag tctattattc ctttcgttcc aaggttttta cgcttttagc
    50881 aacaagctta cacactgagc gtttcggact taccatatca tttcgttgga gattttatca
    50941 tcaattttta gattaaaaaa gatttcccaa tcttcacaaa cttctgtagc aggaattgta
    51001 tgaatctttc taagtatctt tcctgcttct acaccatatg tgtattgttg gttttctgaa
    51061 taagttaaaa tgctatctat tgcatctctt ccgtctatcc atccattcgt gtaaagaatg
    51121 tacttcgtca tcgcagagtt caatgctaat tggtttacac atcggaactc caagagaagc
    51181 tactttctcc atcatatcaa attcaaattt ttttataatc taacttcgac ttatcagaaa
    51241 cacgcaagaa atatttttac tgattttgat ctgtcacaca atatttttta tcatctgacc
    51301 agcctttatt tatggctatc ttactactaa aatccatcaa gcacactccg attcacttta
    51361 caacactttt tgcagttttc actagtaacc tatccagttc gtctacactt ttatttccta
    51421 gatccatttt tacattatga aagttagtca attttctcta tgatgtttcc aagtttatcc
    51481 aatacaagac aagaatgatc atttagtgga attatgggaa cattaacgag ttcttcagct
    51541 ctatccttat ttgctttatc attccaggaa tcataatgga cactaattaa aaactgacta
    51601 aagagtccta atccattttt tatctttatc tgatgatctg aattatcatt aggtgagaca
    51661 tagacttttt ctcctaatag tagggctcct gcagaaaatc ctataatttt tgcctcttta
    51721 ttaagcatat gatcgatata acttttgaac tcctgattaa cataagtagc aatatatttt
    51781 tccgtatttc caccaccgat gataattatg tcagcatcta gatagctatc aagatcaatc
    51841 tgctcagtgt ccaggagaaa gtaatcaatg tttagattag gaaattgact ttgaaaaact
    51901 tccgtgtact ttttcatgta cggttcccaa ttttctcgaa aaactgtaaa aatgataatt
    51961 cttttaatct tggttgataa tacaatttta tcaacaatac tatatttctt cattggggga
    52021 ttcccaccca tcaaaaaaat t
//
LOCUS       DAVHSI010000014        51994 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.014, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000014 DAVHSI010000000
VERSION     DAVHSI010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.014"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            57..437
                     /locus_tag="VVR21_000889"
     CDS             57..437
                     /locus_tag="VVR21_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054795.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTTVNTAATTLNGGA
                     TAGTFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            972..1664
                     /locus_tag="VVR21_000890"
     CDS             972..1664
                     /locus_tag="VVR21_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU6054796.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1717..4128
                     /locus_tag="VVR21_000891"
     CDS             1717..4128
                     /locus_tag="VVR21_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU6054797.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQSPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVCFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4378..5079
                     /locus_tag="VVR21_000892"
     CDS             4378..5079
                     /locus_tag="VVR21_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054798.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5081..7789
                     /locus_tag="VVR21_000893"
     CDS             5081..7789
                     /locus_tag="VVR21_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6054799.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7885..8376)
                     /gene="tpx"
                     /locus_tag="VVR21_000894"
     CDS             complement(7885..8376)
                     /gene="tpx"
                     /locus_tag="VVR21_000894"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU6054800.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNMVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8499..9428)
                     /gene="psaA"
                     /locus_tag="VVR21_000895"
     CDS             complement(8499..9428)
                     /gene="psaA"
                     /locus_tag="VVR21_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU6054801.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9460..10308)
                     /locus_tag="VVR21_000896"
     CDS             complement(9460..10308)
                     /locus_tag="VVR21_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6054802.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10305..11027)
                     /locus_tag="VVR21_000897"
     CDS             complement(10305..11027)
                     /locus_tag="VVR21_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6054803.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11318..13210
                     /gene="pepO"
                     /locus_tag="VVR21_000898"
     CDS             11318..13210
                     /gene="pepO"
                     /locus_tag="VVR21_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU6054804.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHHLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13332..13961)
                     /locus_tag="VVR21_000899"
     CDS             complement(13332..13961)
                     /locus_tag="VVR21_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6054805.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14955..17177
                     /locus_tag="VVR21_000900"
     CDS             14955..17177
                     /locus_tag="VVR21_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU6054806.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVSGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17207..17650
                     /locus_tag="VVR21_000901"
     CDS             17207..17650
                     /locus_tag="VVR21_000901"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU6054807.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(18121..18534)
                     /locus_tag="VVR21_000902"
     CDS             complement(18121..18534)
                     /locus_tag="VVR21_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054808.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(18665..19312)
                     /locus_tag="VVR21_000903"
     CDS             complement(18665..19312)
                     /locus_tag="VVR21_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU6054809.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(19338..19529)
                     /locus_tag="VVR21_000904"
     CDS             complement(19338..19529)
                     /locus_tag="VVR21_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054810.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGGRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(19510..20160)
                     /locus_tag="VVR21_000905"
     CDS             complement(19510..20160)
                     /locus_tag="VVR21_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU6054811.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQMNMDIAKQLYVEKIN"
     gene            20272..21114
                     /locus_tag="VVR21_000906"
     CDS             20272..21114
                     /locus_tag="VVR21_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU6054812.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21190..21627
                     /locus_tag="VVR21_000907"
     CDS             21190..21627
                     /locus_tag="VVR21_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU6054813.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            21696..21998
                     /locus_tag="VVR21_000908"
     CDS             21696..21998
                     /locus_tag="VVR21_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054814.1"
                     /translation="MYLVIGIVLAFIVSFWKYNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPNYLSMLFDFY"
     gene            complement(22089..23162)
                     /locus_tag="VVR21_000909"
     CDS             complement(22089..23162)
                     /locus_tag="VVR21_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU6054815.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKLFGQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            23318..23995
                     /locus_tag="VVR21_000910"
     CDS             23318..23995
                     /locus_tag="VVR21_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6054816.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            23988..24962
                     /locus_tag="VVR21_000911"
     CDS             23988..24962
                     /locus_tag="VVR21_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6054817.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(25011..26954)
                     /gene="thrS"
                     /locus_tag="VVR21_000912"
     CDS             complement(25011..26954)
                     /gene="thrS"
                     /locus_tag="VVR21_000912"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU6054818.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(27012..27188)
                     /locus_tag="VVR21_000913"
     CDS             complement(27012..27188)
                     /locus_tag="VVR21_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU6054819.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(27195..27335)
                     /locus_tag="VVR21_000914"
     CDS             complement(27195..27335)
                     /locus_tag="VVR21_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU6054820.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(27766..27966)
                     /locus_tag="VVR21_000915"
     CDS             complement(27766..27966)
                     /locus_tag="VVR21_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054821.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLEELYINNLL
                     FFTPLVILIISLLYSYRFRFSL"
     gene            28205..28834
                     /locus_tag="VVR21_000916"
     CDS             28205..28834
                     /locus_tag="VVR21_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6054822.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            28975..29244
                     /gene="rpsO"
                     /locus_tag="VVR21_000917"
     CDS             28975..29244
                     /gene="rpsO"
                     /locus_tag="VVR21_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU6054823.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            30058..30672
                     /locus_tag="VVR21_000918"
     CDS             30058..30672
                     /locus_tag="VVR21_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU6054824.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(30963..31712)
                     /locus_tag="VVR21_000919"
     CDS             complement(30963..31712)
                     /locus_tag="VVR21_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU6054825.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            31845..34181
                     /locus_tag="VVR21_000920"
     CDS             31845..34181
                     /locus_tag="VVR21_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU6054826.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVSLNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DSLLLSGSFLASGSVLARVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            34710..36173
                     /locus_tag="VVR21_000921"
     CDS             34710..36173
                     /locus_tag="VVR21_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU6054827.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            36166..36594
                     /locus_tag="VVR21_000922"
     CDS             36166..36594
                     /locus_tag="VVR21_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6054828.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            36572..37021
                     /locus_tag="VVR21_000923"
     CDS             36572..37021
                     /locus_tag="VVR21_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6054829.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            37049..37360
                     /locus_tag="VVR21_000924"
     CDS             37049..37360
                     /locus_tag="VVR21_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6054830.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            37386..38471
                     /locus_tag="VVR21_000925"
     CDS             37386..38471
                     /locus_tag="VVR21_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEU6054831.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            38482..39177
                     /locus_tag="VVR21_000926"
     CDS             38482..39177
                     /locus_tag="VVR21_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU6054832.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            39214..41184
                     /gene="tkt"
                     /locus_tag="VVR21_000927"
     CDS             39214..41184
                     /gene="tkt"
                     /locus_tag="VVR21_000927"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6054833.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYNDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYIKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            41554..42891
                     /locus_tag="VVR21_000928"
                     /pseudo
     CDS             41554..42891
                     /locus_tag="VVR21_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(43008..43496)
                     /locus_tag="VVR21_000929"
     CDS             complement(43008..43496)
                     /locus_tag="VVR21_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEU6054834.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDVLNFEEFIRETEHSLNIREKN
                     TG"
     gene            complement(43490..43958)
                     /locus_tag="VVR21_000930"
                     /pseudo
     CDS             complement(43490..43958)
                     /locus_tag="VVR21_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            44507..45184
                     /locus_tag="VVR21_000931"
     CDS             44507..45184
                     /locus_tag="VVR21_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU6054835.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            45171..45968
                     /locus_tag="VVR21_000932"
     CDS             45171..45968
                     /locus_tag="VVR21_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU6054836.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            45985..47088
                     /locus_tag="VVR21_000933"
     CDS             45985..47088
                     /locus_tag="VVR21_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU6054837.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLDPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            47089..47169
                     /locus_tag="VVR21_000934"
                     /pseudo
     CDS             47089..47169
                     /locus_tag="VVR21_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            47389..48408
                     /gene="galE"
                     /locus_tag="VVR21_000935"
     CDS             47389..48408
                     /gene="galE"
                     /locus_tag="VVR21_000935"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6054838.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            48410..49375
                     /locus_tag="VVR21_000936"
     CDS             48410..49375
                     /locus_tag="VVR21_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6054839.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(49426..49632)
                     /locus_tag="VVR21_000937"
     CDS             complement(49426..49632)
                     /locus_tag="VVR21_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU6054840.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            49684..50160
                     /locus_tag="VVR21_000938"
     CDS             49684..50160
                     /locus_tag="VVR21_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU6054841.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            50169..50840
                     /locus_tag="VVR21_000939"
     CDS             50169..50840
                     /locus_tag="VVR21_000939"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU6054842.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAVTYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPQVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            50970..51308
                     /locus_tag="VVR21_000940"
     CDS             50970..51308
                     /locus_tag="VVR21_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU6054843.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            51311..51940
                     /locus_tag="VVR21_000941"
     CDS             51311..51940
                     /locus_tag="VVR21_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU6054844.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
BASE COUNT        15367 a         9523 c        11673 g        15431 t
ORIGIN      
        1 aaaaagcaaa tatgatacaa ttttatttga aaaaaaataa aaaaggagat tttattatga
       61 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
      121 ttattggtcc ttttgtcttg ttgggaacaa cggtaaacac agctgctaca actcttaatg
      181 gaggagctac tgcagggact ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
      241 caaatcttgt tcttggtatc attgctattg tttactataa aggagataag cgtgtaggtg
      301 cagctccgtc tgtactaatg attgtttctg gtggagttag tctcattcca ttcttaggat
      361 gggttggggg gattcttgct attatcggag gatctctatt ccttgcaaca ttgaagaaat
      421 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
      481 ggagtagctc tattatctct ttctcttcta gttgcatgtg gaacataaag ttcaaagaat
      541 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
      601 actttcgata caccggttgt aacagacgat gcgattgaat caatacgcac ttatgcagat
      661 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
      721 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
      781 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac agccaaaaac
      841 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
      901 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
      961 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
     1021 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
     1081 ttgacgctgg taaattgatc aaagaagctg gtatcgaatt tgaccaagct tacacttcag
     1141 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattatggg
     1201 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
     1261 acaaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
     1321 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
     1381 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
     1441 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
     1501 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
     1561 cagatgatga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
     1621 atgaaaaatt gaacgttgtt tctgaatact accttggaaa ataaaaaatt gtaagcctag
     1681 gattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
     1741 tatgtactgg cctacaagca accagcttca accacttaca tgggttggga agaagaagct
     1801 ttaccgatag gtaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
     1861 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
     1921 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
     1981 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
     2041 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
     2101 acgactttgt ctcaggtgac ggactatcag agacagttga atattagtaa ggcacttgcg
     2161 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
     2221 gatgatctct tggttcaatg ttttactaag gaagggttgg aaactctaga ttttactata
     2281 gaactatcct tgacctgtga tttggcttct aatggaaagt atgagcagga aaaatctgat
     2341 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
     2401 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
     2461 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
     2521 acggattttg cccaaagtcc tgctagcaat tatcgcaaga aactagattt agagcaacag
     2581 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
     2641 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc tgatgttgac
     2701 gcatccacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
     2761 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
     2821 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
     2881 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
     2941 ctagagacgg tctttccagt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
     3001 gcggctgtaa agtatgcagg aatcgtctct cagaaaggtg aggagaatgg ttggttggtt
     3061 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
     3121 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
     3181 gaccaagact atctcagaga gaaaatttat cccatgttga gggaaacggt ttgtttttgg
     3241 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
     3301 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
     3361 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
     3421 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
     3481 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
     3541 catgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
     3601 tatattgaag cggcgcgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
     3661 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
     3721 ttggcagagc agttaaagac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
     3781 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
     3841 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
     3901 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
     3961 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
     4021 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
     4081 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
     4141 aggcagtaat ttgaaacttc cttttaataa ggatttgaga atataggcag tttccaacta
     4201 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
     4261 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
     4321 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
     4381 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
     4441 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
     4501 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
     4561 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
     4621 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
     4681 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
     4741 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
     4801 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattcttctt
     4861 tgtgatgaac ctactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
     4921 caagatatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
     4981 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
     5041 aaccaacatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
     5101 ttggaaggac ttaattcagt ccttcacagg ctccaagggg cgttttttat ccatcttgat
     5161 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
     5221 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
     5281 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
     5341 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
     5401 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacaa
     5461 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
     5521 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
     5581 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
     5641 gactctgaca gcctatgggg tgattttacc tagtcagttt gatcagaaag tctacaatat
     5701 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
     5761 aaaatccaag caacatcagg aagagcttga acaaacttta tcagataatg gcaaggtacg
     5821 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agacccttga
     5881 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
     5941 acaggctcaa gaaagtcaac tagccttgtt tcctcaagtt cagagagagc aggctagtgc
     6001 tcaacttacc caagccaagc aggaattggg caaggaagag gataaactaa agcaagctga
     6061 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggacgattt
     6121 ggcggagcca aggtatcagg tctataatcg tcagaccatg ccaggtggtc agggctatct
     6181 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
     6241 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
     6301 aactcatgca gggattttta aggccttggg ttaccgtagt aaggatatta tcgccaagtt
     6361 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
     6421 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
     6481 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
     6541 tgtgttacca gcctatctgg tggcttggag ggaacttcat gccgaagcag cccagcttct
     6601 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
     6661 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
     6721 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
     6781 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
     6841 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
     6901 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
     6961 tttcaaaggc aaggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
     7021 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
     7081 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
     7141 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
     7201 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
     7261 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
     7321 atctgcggtg tccagcgttg tccaaaatgc ttcagccatt cgactcttcg actctgtcgc
     7381 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
     7441 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactac
     7501 caaggttctt ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
     7561 gctatccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
     7621 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
     7681 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
     7741 ttatctgaga aaggttgata tgttagaagc cctgaaatct gtagagtaag gtagttattt
     7801 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
     7861 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
     7921 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
     7981 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgtg
     8041 cccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
     8101 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccatgttgtc
     8161 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
     8221 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
     8281 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
     8341 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
     8401 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg ggcatagaaa
     8461 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
     8521 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
     8581 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
     8641 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
     8701 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
     8761 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
     8821 gttacaatga gtttcttttc agcagggatt ttattaaatt tatccttact ttctttatca
     8881 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
     8941 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
     9001 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcgag gtagataaca
     9061 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
     9121 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
     9181 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc
     9241 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
     9301 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
     9361 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
     9421 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
     9481 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
     9541 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
     9601 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatacttt tcagactatt
     9661 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca ggatagttcc
     9721 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
     9781 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
     9841 ttgcttgaag aaaatccaaa ttaacaagag gatggctgcc cccacaccca tagtaataaa
     9901 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
     9961 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    10021 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    10081 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    10141 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    10201 aatgaaacat cccacagctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    10261 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    10321 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    10381 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    10441 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    10501 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    10561 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    10621 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    10681 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    10741 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    10801 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    10861 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    10921 tttggaccaa tgatgccggt aattgttggt ccatggagca ctagtgaaat atccttaagt
    10981 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    11041 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    11101 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    11161 aacgcatagt atcaagtgta aagaacttgg aattatgcgt tttatcatgg aaaggttttt
    11221 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    11281 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    11341 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    11401 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    11461 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    11521 ccaccaccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    11581 actccttaaa gaattccaag aattggagac ttttgcggat tttacagcta aactagcaga
    11641 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    11701 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    11761 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagtagcgc
    11821 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    11881 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    11941 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    12001 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    12061 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    12121 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    12181 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    12241 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    12301 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    12361 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    12421 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    12481 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    12541 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    12601 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    12661 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    12721 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    12781 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    12841 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    12901 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    12961 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    13021 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    13081 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    13141 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    13201 tatttggtaa tgcaaaaaat ctagttatca gaaaaaggca tccaatcacg tgtgaaaacc
    13261 ttgataggat gccttttgta atagaaagat ttgctggata gtttacttaa atttcgattg
    13321 tcatcatctt gctagaaaaa gggattgaag gccttttcgt gagcgatagt agtagctgga
    13381 ccatgtcctg gatagacatc gtagtttggt agggtgaaga gttgggtctg gatactatga
    13441 aggagttgct ccatgctacc agtcggaagg tcggtccgtc cgatagtttc gcggaataga
    13501 gcatctcccg tcaagactag gtgagcatca ggaaagacta gggaaacacc accgatagag
    13561 tgccctgggg tcggtagaac cttaaaacga aattcctcta gttggtattc ttcgtgaaag
    13621 acaaaggtgt gttctgcagg ttttgtgacc acatctgcca tatcatcgtg gcgagggaga
    13681 ccggagagat tatcgacagg agtgtagagc cagctggctt cgctctctgc gatatagaca
    13741 ggaggattgc caaacgtctc gcgaaccaag tccagactca tgatatggtc ataatgggcg
    13801 tgggtcaaga gaatagcaca gatcggtttg ttgatcttct cgattgtctg acgaatggct
    13861 tcccaatgac taccaggatc gacgacgatg aggtgctttt cgccttctag ataataggta
    13921 ttttcatagg caacaggatt cacggtttta tggattttca tactagctcc aatctcaaag
    13981 aatgtactaa tactcttcga aaatctcttc aaaccgcgtc aactttatct gcaacctcaa
    14041 agcagtgctt tgaacagcct gcggctagct ttctagtttg ctctttgatt ttcattgagt
    14101 ataaattaag tatagcacag ttagggagaa taggtaagga tttaaaatga acttaaaaac
    14161 cagcatgact agatgaagac aggctggtta tcaatttatc aatattggaa aggtgtcaat
    14221 tgcccttcat aggttgcata aactccgtca ttagcttgtt tgatagacgt gatgtttaga
    14281 gtgctaccgt agttggcttc tcatttgtcg ctatattcac tataagttat cctactgggc
    14341 aggttctggt cgttagcata gtattgaacg agttttttat agctttgctg gctgaatagg
    14401 aacaggcagc aaactcctaa cattaggaga gcaaagatag aaatagcagt ttttttcata
    14461 ggtattctcc ttataaacta aaggatagaa gaaagtatct tgaggatttt tatactcttc
    14521 aaaaatctct tcaaaccgcg tcaacgtcgc cttgccgtat atatgtgact gactttgtca
    14581 gtcttatcta caacctcaaa acagtgtttt gagcagcctg cggctagctt tctagtttgc
    14641 tctttgattt tcattgagta ttaattccaa aatccagtca aggtaccagt gtatgtgata
    14701 cgagttccac cgtttatctt tcgtatcttc aatggaattg gggaaatcag aaagtctttg
    14761 ggttacaata tggtttccgt tcttctatct ctccttctat cacctaagtt taaaatctaa
    14821 cttcgtagta tattatgggt caataattca gaattatcaa gcaattttga attatttttt
    14881 tcttattctg ttccaatcta gttttcatat tcttaaaaaa gtgataaaat ggtaggaaga
    14941 attggagagt agagatgccg aaagaagtga atttaacagg cgaagaagtt gtcgctttaa
    15001 ccaaagaata tttaacggaa gaggatgttc attttgtcca taaggccttg gtctatgctg
    15061 ttgaatgcca cagtggtcaa tatcgcaaat caggcgagcc ttatatcatt caccctatcc
    15121 aagtgtcagg tattttagct aagctaaagc tggatgctgt aacagtagct tgtggattct
    15181 tgcatgatgt ggtggaagat acagatgcga ccttggacga tttggaaaga gagtttggtc
    15241 ctgatgtgcg ggtgattgtt gacggagtta ccaagcttgg caaggtcgag tacaaatcga
    15301 tcgaggagca attagcggaa aatcatcgca agatgctcat ggccatgtct gaggacatcc
    15361 gcgttatttt ggtcaaactg tctgaccgct tgcacaatat gcggaccctg aaacatcttc
    15421 gaaaagacaa gcaggagcgt atttccaaag aaaccatgga aatctatgcc ccacttgccc
    15481 atcgtttggg gatttccagt gtcaaatggg aattagaaga cttgtctttc cgttatctca
    15541 atccaacgga gttttacaag attacccata tgatgaagga aaagcgcagg gagcgtgagg
    15601 ccttggtgga tgaggtagtc acaaaattag aggagtatac gacagaacgt cacttgaaag
    15661 ggaagattta tggtcgtccc aagcatattt actcaatttt ccgcaaaatg caggacaaga
    15721 gaaaacggtt tgaggaaatc tatgatctga ttgctattcg ttgtatttta gatacccaaa
    15781 gtgatgttta tgccatgctt ggttacgtgc atgaattttg gaaaccgatg ccaggtcgct
    15841 tcaaagacta tattgccaac cgcaaggcca atggttatca gtctatccat acgactgttt
    15901 atggaccaaa agggccgatt gaattccaga ttcgaaccaa ggaaatgcac gaggtggctg
    15961 agtacggggt tgcggctcac tgggcttata agaaaggtat aaaggggcaa gttaacagca
    16021 aggaatcagc tattggaatg aactggatca aggagatgat ggagctccaa gaccaggctg
    16081 atgatgctaa ggaatttgtg gactctgtta aggaaaacta tttggctgag gagatttacg
    16141 tttttacccc agatggagct gtccgttccc ttcccaaaga ttcaggaccg attgattttg
    16201 cctacgaaat ccataccaag gtcggtgaaa aagcaactgg tgccaaggtc aatggccgca
    16261 tggttccact gacaaccaag ttaaagacag gggatcaggt tgaaattatc gccaacccga
    16321 actcctttgg acctagccgt gactggctca atatggtcaa gactagcaag gcgcgcaata
    16381 agattcgcca gttctttaaa aaccaagata aggaattgtc tgtcaacaag ggtcgtgaga
    16441 tgctgatggc tcagttccaa gaaaatggct atgtggcaaa taaatttatg gacaagcgcc
    16501 acatggatca agttctgcaa aagaccagtt acaagacaga agactccctc tttgcggcca
    16561 ttggttttgg ggaaatcggt gcgattaccg tctttaaccg tctgactgaa aaggaacgcc
    16621 gtgaggaaga gcgtgccaag gccaaggctg aggcagagga gcttgtcaaa ggtggcgagg
    16681 tcaaggttga aaataaagaa actctcaagg tcaagcatga ggggggagtg gttattgaag
    16741 gtgcttctgg tctcctagtg cggattgcta agtgttgtaa ccccgtgcct ggtgacgata
    16801 ttgttggcta cattaccaag ggtcgtggtg tggctattca ccgtgtggac tgtatgaacc
    16861 tgcgtgccca agaaaactac gagcaacgtc tccttgatgt ggaatgggaa gaccagtact
    16921 ctagctcaaa taaggagtat atggcccata tcgatatcta cggtctcaac cgtacaggac
    16981 tgttgaacga tgtactgcaa gttctttcaa atacaaccaa gaatatttca acggtcaatg
    17041 cccaaccaac caaggatatg aagtttgcta atatccatgt gtccttcggt attgccaacc
    17101 tctctacact gaccacggtt gtcgataaaa ttaagagtgt gccagaagtt tactctgtca
    17161 aacggaccaa cggctagttg tcctagctct tactagaaag gctattatga aaatcattat
    17221 ccaacgggtt aaaaaagccc aagtgagtat agaaggccag attcagggaa aaatcaatca
    17281 gggactttta ttgctggttg gtgttggacc agaggaccaa gaggaagatt tggactatgc
    17341 tgtgagaaaa ctggtcaata tgcggatttt ttcagacgca gaaggcaaga tgaacctgtc
    17401 tgtcaaagat attgaaggag aaatcctctc tatttctcag tttaccctct ttgcggatac
    17461 taagaaaggc aatcgtccag cctttacagg ggcagctaaa cctgatatgg catcagactt
    17521 ctatgatgct ttcaatcaaa aattagcgca agaagtgccc gttcagacag gtatctttgg
    17581 agcagatatg caggttgagc tggttaataa cggacctgtt accattatcc tagatactaa
    17641 aaagagataa gaaagaccaa gcccagtcgg cttggtcttt ctcatcgatc ataaaatact
    17701 ccaaaaagaa atcggttctt gatatgctta ggggaagtct cttttcaggc tttggcagat
    17761 gcgataggaa gggatgagat gtcctaggat gaggagagtt ccctgaagga aaagtggaat
    17821 atcacttaaa gacaccaagg agagaatcat caggctatcc cataggagaa tttgtaaagc
    17881 aaaacgccag aatctcggtc taatctggga atagagttaa ctaaagtggt cacaaagttg
    17941 gtttgaaaga taggtcaata gcacaggatg aaagaaaatg agccaaccgc tataaatcaa
    18001 aatccagtcc caagtaagcc ccccttttaa atgtcaaaaa tgccagcatg attccatcaa
    18061 tgacaaggag ttgaatggtt ttgatgaaga tgattttttc atgctaaaac ctccttttcc
    18121 ttagagacac tcccataaag agatgtgttt gtcgtaaaag tctggatagt tttctcttag
    18181 gtagtcagct gtcatataat aaaaagtaga atggcaagca gtgataattg acataagaga
    18241 tgaaaaacgc tgagaactaa tgaaggctaa gagaacaaaa aatagaaaat caatggtgag
    18301 aacccctaaa tagtagaagc gaatcttttt attgatttga ggataaatct cagcgaattg
    18361 atgtttgagt cggacgacca agagaaatag caggagtcct tgatcaagga agaaaattaa
    18421 accagagagc aagagccact caaaagatgt ctcgagtcta gtgataaaaa atgcaaatag
    18481 tagcaaatca ataactgcaa ttgctataaa atggattcta tagagttttt tcatgacaag
    18541 accttcctct tttatctaac ttcattctac tccaaaagaa tgggagttac aactaaaatg
    18601 ataaaaatag cagaggggag attctcttaa gttggctagt attctttatt tgagtttcct
    18661 tctattatct aacttcttca tcattccaga caaataaagc tccgattgca ttgaggatat
    18721 aaaagatgta tttaccgata ttggcgaagt ttccttgaat accagctttt gtcagctgaa
    18781 cgaaattgta aatcaaccaa aagccccact gagttgttag tttcaatgca ttcaaagcat
    18841 tggcaatgag ggacagtgca aaggcaatag ttgttacgta ggcaaggaga ttcatcttgc
    18901 ccccatatcc gatatagttg gtcacaaagg caaagaggaa ggcgatgatg gaaatgatga
    18961 tggccgccaa ttttacctgt ttttggctca tttggttggg tctgccttct tgcgaagctt
    19021 tccatttctt tatagcaaag gtataaatga ggaaggtgac gggataggta atgatggccg
    19081 ccttatttcc aaggatataa tcaatagcac cggacaaaat ggtattaaca ataccaaagt
    19141 aatttcccca tttgcttaat ttccccgtga aacgagtgga caacatggaa atcccaacgt
    19201 tggttacgga aatcaatcca aagggtacaa gagctgtcca tagtccccag tctacaaatt
    19261 tatggaggcg tgagttgaga taaccagatg caatcgcaat cccaacgacc aaagcaaccc
    19321 cgaagaggtc aaactattta gatgtagcaa aaatttttag tgattttttc ataggttaaa
    19381 ctacctttct ttttttcaaa tattctccca tttttttcaa atattctccc accaaatgaa
    19441 agtaaaataa aatgatagaa ataaaaccct gaaaataaaa ctttcagggt tggtagggga
    19501 cttgagaaat tagttgattt tctcgacata gagttgtttt gcaatgtcca tattcatttg
    19561 taaatcctcg tcgttactga ggatagtgaa ggtattgctg aagccatcaa actgcttgac
    19621 ttggagctgg tcaccgatgt gaagtgagtg cttgtccaga taatggagaa tgtcaaaact
    19681 atcgtgcacc cgagtcaggc ggtaggcgcc agcttccttg atatcagcta gtgggaggtt
    19741 attgatttca acgaggagtt ctcccttggc aggaatagtt cctccgtggg ggcaggtttt
    19801 agggaaacct agcagtttat ctagtctttc cacgaacagg tcagagacag tgtgttccaa
    19861 gacctcagct tcctcgtgaa tctggtcact tgtatagtct aaatgatgaa ctagaaaaac
    19921 ttcaatcaag cggtgcttac gatagagctc agagaccagt ttgagaccga ggtcagtcag
    19981 tagatagcca cattccttgt cctttaggat gagattttca cttttcattc gtttgatcat
    20041 ttcagttacg gcagggggag agacttgcat gcgagccgca atttccttgt tggtaatctt
    20101 atgcaggtct atgccaattt cataaataca ttttagatag tcttctttgt ttggggtcat
    20161 tcgtttcctc ttgtctaata tctttatcta gtatatcaaa aaaagctaga tttctctagc
    20221 tgtgactttt tatgttatac ttattgcaag agaaaaaacg aggagatgga tatgacgaaa
    20281 atagctcttc tttcagatat tcatggaaat accaccgcct tggaggctgt tttggcagat
    20341 gctcagcagc taggagtgga tgaatactgg cttttgggag atattctcat gccagggaca
    20401 ggacgtagaa ggattttgga cttgttggat caactaccga ttacggctag agttttggga
    20461 aactgggaag acagtctttg gcatggtgtc cgtaaggaat tggacagtac tcgccccagt
    20521 caacgctatc tcttgcgcca gtgccagtat gttttagagg aaatttccct agaagaaatt
    20581 gaagtgctcc acaatcaacc tcttcaaatt catcgtcagt ttggggattt gacggtggga
    20641 attagccatc atctgcctga taagaactgg gggcgagagt tgattcatac tggcaaacaa
    20701 gaggagtttg accgcttggt gactcatcct ccctgtgata ttgctgttta tggacatatt
    20761 caccagcagt tgcttcgtta cgggactggt gggcaattga ttgtcaatcc gggttcgatt
    20821 gggcaacctt tctttttgga cgctcagcta cggaaggact tgcgggccca gtatatgatt
    20881 ttggagtttg atgacaaggg cctggtagat atggacttcc gacgggtaga ctacgatgtg
    20941 gcagctgaat tgcagctggc taaagacctg agacttccct attttgaggt ttactatgaa
    21001 agtctggtca atgggatcca ccatactcat catcaggaat ttttgagaga attggctcag
    21061 aaagagggct gcgatcggga gttagacgac tggttgaaaa gtggtaacga ttgacattac
    21121 aactaaaaag ggtataataa tagaaaaaga agagtagagg cagggtagcc tcgtaaaaag
    21181 gagaagagga tgcaaattcc aagtagattt accattgcga ctcatatgct gataatcatt
    21241 gccctcgagg ggaaggaaag caaggtgacc agtgattttc tggctgctag tgtcggggtc
    21301 aatcctgtca ttatcagaaa gatcttgtcc cagttgaaga aggcagagct gatttcagta
    21361 gcgcgtggaa cgggcggaac agagattgtc aaggacctta aggatattag tcttttagat
    21421 gtttatcagg cggtcgaatg tcttggtaag acaggtcaac tcttcagttt ccatgacaat
    21481 ccgaatccaa attgccctgt aggagctcat attcatgatg ttttggatca aaaattggag
    21541 agaattcagt tgactatgga ggcagaactt ggtcaaacca gtctagaaaa agtcgtggcc
    21601 gatgcagaga gtcagatgaa ggattaagag ggataaatgc cctctttttt tctttggata
    21661 attatgataa aatgtagcta ttaaaggagt aagaaatgta tctcgttata ggaattgtat
    21721 tagcctttat agtgtcattt tggaagtata atagaagttt gtggaatcca gtattatttt
    21781 tattatccct catttcaagt tatttttatc tatcctacct tttttataaa aatggatacg
    21841 agaatgttca gttagctttt tatgtatttg cctttgtctt acttcctttt ttgctttttc
    21901 taagtggcat ctttttaatc tataatgggg tcattttgtt gaaacgagag ggacgttcca
    21961 agcccaatta tctttcaatg ctatttgatt tttattgact attagattct atttaaaaag
    22021 acttagaatg cacatgaaag tatgtattct aggtcttttg ttttgtatac atttaatttt
    22081 caagagtatt atctattttt ccatgcctgg taacgagtat caatcaataa ctgggtaagg
    22141 cgacccaagg tttctctttc ttctggagtg agggattgag cttggacaaa gagatgatga
    22201 atgtattcaa gcgcctttaa ggaagccaag tcattgatag agctaatacc agcctcaaga
    22261 atagtgccaa agaagaggtc gaagtagagc tgaagttctt cgtcagggac tgtggccacc
    22321 cattctttaa aggttgtgtc tacttgctgg ctatcactgt tggtcttatc cagttggccg
    22381 aagagcttgt cctcaatctg ccaactaaag gtatcgtgct gggcgatgcc acccagggca
    22441 gtactctgaa cgatgatttg gtgagcagga atttccagca tcataccgat aatggaacct
    22501 tgtggaatga atatcttgct tctatccatt atcctttgat aacccgcagt ctgtgtcaat
    22561 tcttgatgga gaccaggtgc atcaaatgta taaactgctg tgatctgatt ttgcaaactt
    22621 tgctcaattt ggctagcagc atagatagcg agatttcctc ccttggaatg cccggccaga
    22681 ataacctttt gcttaggatg atgagcaaaa aagttcttta aatagcgaag ggcgtgcttt
    22741 tgagcaggaa tttccttcat ataggtcagg tggaaatctt ccttccagcc aatgatactg
    22801 tcatctgtcc cacgaaagac aatcagatag gtatcgaggc tgacacgata agtcatagcc
    22861 gcaaattgct tttgcagttc agggtcgatg tcgttgataa aatgggagag tttgcaattt
    22921 ttgaagcgct tgtgttgagc caattcatct aataattgaa ggcgattttt gctagtaagc
    22981 atggtaggct ctcttggaac ctgaggtgct agatctaaaa gacgttgagg aagtgtggag
    23041 accagattat caaaggagag gtaggtgatt tctattaagg ttagaatgtc taactcattc
    23101 aagggaaggt cgtaataaga atcatatgcg acatctttca gatagtcaaa aatattggcc
    23161 ataagagctc ctttcttttt atttatctta gcaaatttcc ctcaaattag ctagtagcat
    23221 agcctgtttg tactggctaa aaacaggcta tttcaaattc agtttcagac catctagcat
    23281 ggaaaaatct gttataataa tagaaaagga gaagcgcatg cacaagattt tattaataga
    23341 agatgatcag gtcattcgtc aacagattgg gaaaatgctc tctgaatggg gatttgaagt
    23401 ggtcctggta gaagacttta tggaagtttt gagtctattt gttcagtcgg aacctcatct
    23461 ggtcctcatg gatattggtt tgcccttgtt taatggttat cactggtgtc aggaaatccg
    23521 caagatttcc aaggtaccta tcatgtttct ttcttcgaga gaccaggcta tggatattgt
    23581 catggcaatc aatatggggg cggatgactt tgtgaccaag ccttttgacc agcaggttct
    23641 tttagctaag gttcagggct tgttgcgtcg ttcctatgag tttgggcgtg atgagagttt
    23701 gctggaatat gctggtgtta tcctcaatac caaatccatg gatttacatt atcaagggca
    23761 agtcttgaat ttgaccaaga atgaattcca gattttacgc gtgttatttg agcatgcagg
    23821 caacatcgta gcacgtgacg acctgatgcg ggaactttgg aacagtgact ttttcattga
    23881 tgataatacc ctctctgtca atgtggctcg tttgcgtaaa aagttggagg agcagggatt
    23941 ggtaggattt atcgagacca agaaaggaat agggtacgga ttgaagcatg cttgattgga
    24001 aacaattttt tctagcctat ctgcgctccc gtagtcgtct ttttatctat ctgctttctt
    24061 tggcatttct tgtcttactc tttcagtttt tatttgccag tctaggaatt tacttcctct
    24121 actttttctt cttgtgttgc tttgtaacca tattattttt cacttgggac atattggtgg
    24181 aaacgcaggt ctatcgccag gaacttctct atggagagag ggaagccaag tctcctttgg
    24241 aaatagcttt agcagaaaaa ttagaagcgc gtgagatgga actctatcag cagaggtcaa
    24301 aagcagaaag aaaactgacg gatttgctgg attactatac cttgtgggtc catcagataa
    24361 agacccccat tgcagccagt caactcttag ttgcagaagt ggtcgaccgc caactgaagc
    24421 agcagctaga acaggaaatt ttcaaaatcg actcctatac caacctagtt ttacagtacc
    24481 tgcgtttaga aagtttccat gatgatttgc tcttaaagca ggttcaaatt gaggacttgg
    24541 tcaaggaaat aattcgtaaa tatgctcttt tctttattca aaaaggctta aatgtcaatc
    24601 tacatgacct tgataaagaa atcgtgacgg ataaaaagtg gctgctagtg gttattgagc
    24661 aaatcatctc aaacagtctc aagtacacca aggaaggtgg tctggagatt tatatggatg
    24721 accaagagct ttgtatcaaa gatacgggaa tcgggataaa aaacagtgat gtcctccgag
    24781 tatttgaacg tggcttttca ggatacaatg gccgtttgac ccagcagtcc tctggacttg
    24841 gcctttatct atctaagaaa atttctgaag aactggggca ccagattcgt atcgagtctg
    24901 aggtcggaaa aggaacgaca gtgcggattc agtttgctca agtgaactta gtccttgagt
    24961 aaaaatagat gagaaaaagc ctccagattg gaggctttta tgctagactc ttatttctca
    25021 acgcgtgatt tgttggcgat atcagctagg atagcttgaa caaaattatc aactgagaca
    25081 gtttgtgttt ctttttggcc gtagcgacga acgttgactg tttcgtcttc catttctttg
    25141 tctccaacaa ttaattggta aggaatcttg ctggtttgtg aagcacggat cttgaactgc
    25201 attttttcat tgcgctcatc tacgtctgca cggacaccgc ggtcacggag tttcttggcc
    25261 acttcccaag cgtagtccac gtgtttttcg ttagatactg ggatgagggt tacttggtgt
    25321 ggtgccagcc atgttgggaa ggcccccttg tagttctcaa tcaagatagc tgtgaagcgt
    25381 tccatagttg agataacccc acggtggatc atgactggac ggtgatcttc gccatcagct
    25441 ccgatgtatt tgaggtcgaa gcgttctggc aacaagaaat caagttggat agtagaaagg
    25501 gtttcttctt ttccaagggc agttttaatc tggatatcca attttggtcc gtagaaggct
    25561 gcttcacctt cggcttcaaa gtagtccacg cccatttcat caagagctgc acgaagcatg
    25621 gtttgggcat tttcccacat ctcatcgtta tcaaagtact tatgagtatc ttgagggtca
    25681 cgaagagaga ggcggaagcg gtagtcagtc aagttgaagt cttcataaac atcgataatc
    25741 aactgaaggg cacgttggaa ttcttcttgg atttgttctg gagtaacgaa taggtgaccg
    25801 tcgttgagtg acatttcacg tacacgttga aggccagtga gggcaccaga tttttcgtaa
    25861 cggtgcatca taccgatttc agcgatacgg attggcaatt cacggtaaga gtgaacatgg
    25921 tgtttgaaaa cttggatgtg gtgcggacag ttcattggac gaaggacaaa ttcttccccg
    25981 tcacccatgt ccatggttgg gaacatgtct tcttggtaat gatcccagtg accagaagtc
    26041 ttgtaaagct caacagaagc aagtggtgga gtgtagacgt gttggtagcc agaagccaac
    26101 tctttgttta cgatgtagcg ttccaattca cgacggatag tcgcaccatt tggtaaccag
    26161 aatggcaaac cttgtcccac ttcttgtgaa atcataaaga ggtcaagctc tttaccaagt
    26221 ttacggtggt cacgttcctt agcttcttca cgcatttgaa ggtagttttt caagtctttc
    26281 ttgtcaaacc aagctgtacc gtagatacgt tgcatcatag cgttgtcgct gtttccacgc
    26341 cagtacgcac cagctacatg gagaaggtgg aagatttgga tacgacctgt tgatggaaca
    26401 tgaggtccac ggcagaggtc tacatattca ccctgacgat agatagtcaa accgccttcg
    26461 tcttctgagt gttcttcaat caattccaac ttgtaagggt catttttgaa gatttcacgt
    26521 gcctcgtctt tagtcacttc ttcacgaata gatgggaagt tttctttgac gattttttgc
    26581 atttcttctt cgatacgagg aaggtcttcg ttagagattt gaccagctgt gttgtcagta
    26641 tcgtagtaga aaccatcttc gatggctgga ccaactccca agtgaatgtc tgggaaaaga
    26701 cgacgagctg cttgggcgaa caagtgagct gctgagtgac gcaagattgg aagggcatct
    26761 tcgtgatcag gtgtcacaat ttcgatgctt ccatcttcag tgatagcgcg agtagtgtcg
    26821 atgagtttgc cgttgaattt accagccaag gcttttttag ctagggaatt gctgatagat
    26881 tgggcaattt caaaagttgt tacgccagat tcgaattcac gaacagcgcc atctgggaaa
    26941 gtaatgttaa tcatgatgtt ctcctttttt attatttcat agtttctaag cattgatttt
    27001 ttatcagcag actacttccg agtcctaacg ttcaattgct tttctttatc agagaggaag
    27061 ttttccattt ccgtcagaat gtctatatcc aaacgttgag aaagttctaa tagccaccag
    27121 atattttctg aaagtttttg ttccagtgtg tagggtgttt catcatagta gcgtccttgc
    27181 tttgtcatca ccagtcattg gaaatttcca atatcattag ataaagccaa gaggtcttct
    27241 tctaccgtcc acttgaaatc atgatgctta acttccagtt cgtgataagc ttgtcggatt
    27301 gcccaactgc gctccactaa ttcttgcaac tccataatta gtatcctaat aaaaaaatgc
    27361 gacatcctcg aaaggacgtc gcaacgtggt tccaccttca tttatgtacc tcaaaagaga
    27421 gggacacctc tgatcggctc taacgtggcc accgttttat gttttcataa aaaactcaag
    27481 agtagtatca gtttagactt cctatgcgtt tccagcaacc acgcactctc tagtagaaag
    27541 ggactaagtg acttgtctct atggattatt atagcatgat tgtgagattt ttcaaggatt
    27601 ttgtgaaagt tttttgtttt tcattttttg tagaatatgc ttgatgctaa taccagaatc
    27661 catgccgacc agagcaactg tttcatagat tagcaagtaa attagtataa actcaccaaa
    27721 ggttatgata gtaaagtaaa agagcagtcc gttaccaact aaccatcaaa gtgagaaacg
    27781 gaaacggtag ctatagagta acgatataat caagattacc agaggtgtaa agaagagaag
    27841 attgtttata tagagttcct cgagtgtaag ggggtcagaa acaactagta agaacaactc
    27901 ataaagtggc caataaaaga ataatatgac cagatagtag gggagatggg aatagaatct
    27961 acgcatgata atcacctcgt tttaaaaaaa cagacaactt agatctcttg ctatgattat
    28021 tatagcatgt ttaaaacaag aaagtaaatt tgttgacaaa gaagattttt cttttcacta
    28081 gaatcatagt tagttttctt ggtagaaata ttttgataat aattaagcaa gactattgac
    28141 attgattatt aagagtgtca caattattgt aactaaaata attacaacaa gagaggtata
    28201 aaaaatgaaa ctagcagtta ttgcagcaaa tggacaagcg gggaaagcaa ttgttgaaga
    28261 agcagtcaaa cgaggacatg aagtaacggc tattgttcgt tctgaaaaca aaagtcaagc
    28321 tgagtctatt attaaaaaag atttatttga gttgacaaaa gatgatctta ctggatttga
    28381 tgctgttatt tcagcgtttg gtgcttatac accagatacg ctaccgctcc acagcaaatc
    28441 aatcgaacta tttaatcagc ttcttgctgg aacacagaca cgttttctag ttgtaggggg
    28501 agcaggaagt ctttatatag atgaaacaaa aacgacacga cttttagata cgtctgattt
    28561 tcctgaagaa tttaagtcac tagcaaaaga tcaagcggat gaattggatc ttcttcgtac
    28621 aaaaaataat ctcaactgga cttttgtcag tcctgctgta gattttattc ccgatggtga
    28681 aaaaacagga aactacattc tagcaggaga aatttttact actaatgaaa aaggaataag
    28741 ccagattagt tatgcagatt atgctattgg attggtagat gaacttgaaa aaggtcatca
    28801 tataaaagaa cgtatctctt tacttgaaaa ataataacta tgagagtatt aatgtttgac
    28861 agaaaattta aatcttggta aaataggggt tgtcgtaaag acaaataact tcttcttggt
    28921 tacaggcatg ccaacctgtc actcggatga agccaaataa aaaggagaaa catcatggca
    28981 atctcaaaag agaaaaaaaa tgaaatcatt gcacaatatg cacgtcacga aggtgataca
    29041 ggttcagtag aggttcaagt tgctgtcctt acttgggaaa tcaaccacct taacgaacac
    29101 atcaaacaac acaaaaaaga ccacgctact taccgtggat tgatgaaaaa aatcggtcgc
    29161 cgtcgtaact tgcttgcata cttgcgtaaa aacgacgtta accgttaccg tgagttgatc
    29221 aactctctag gacttcgtcg ctaattcaag atacaaatgc tgtcaaaagc acaaagcaaa
    29281 aataggaaaa ttgacgaaga aacttcagtt tctaggagat tttatctttt ttgccaagtg
    29341 cttaggccgt gttcaattga gcatatcttg ataataaagc tactctaaat tgggtagctt
    29401 ttttgcgttg tcaccttacc tcgctatact caagtataat cttcggttac ggttcctagc
    29461 actgtaaggt aaaataaacc agcttttctc ccttcgggga gatttttttg tttcactgaa
    29521 agtttcgtac gatcttcgcc tcgtcgccta gtctataaac gatttatcta gcaagaatca
    29581 tgatgctaag ggcgtcaaaa atccgtatga aaatagggaa atgacacagt gttcgatgag
    29641 cacaaggagt ttcatctttt tcactaggat tttagcccgg gctaaaatca gctctctgac
    29701 ttcagagggc ttttttattg aggttttatc ggtaacaatt ttggagacta caaaaacctc
    29761 aaatggtatc agctaattac accataaagg tgcgcagtta ctcggctttt caagccgagt
    29821 agctgtatgc aagcccccta gaagagccca ctctttacaa agtaaagtat agtatgttat
    29881 actttacatg gaagtagtca ctgaattcca gttagaaatt actttgtaac tacgttttga
    29941 ggaggagtaa aatgctttcc tacgttcgac attacccact agcgatagct aaattaatgt
    30001 gtctgtgctc tcctgaaatc tgctgattta ttactgacta atacaggagg tttttttatg
    30061 ggacagacaa tcatatctgc tattggtgtt tatatttcca ccagtatcga ttatttaatt
    30121 attttaatta ttttatttgc acagctatca cagaataaac agaaatggca tatttatgcg
    30181 gggcaatatc taggcacagg cttacttgta ggggcgagtt tagttgctgc ttatgtcgtt
    30241 aatttcgtgc ctgaagaatg gatggttgga ttgcttggtt taatccctat ctatttaggg
    30301 attcgctttg caattgttgg agaagatgcg gaagaagaag aggaagaaat tattgaaaga
    30361 ttagaacaaa gcaaggcaaa tcaactgttt tggacagtta cattgctgac aattgcgtct
    30421 ggcggagata atttaggtat ctatatacct tattttgctt cgttagattg gtcacagacc
    30481 ctcgtggcct tgcttgtgtt tgtaatcggc ataattatct tttgcgagat tagtcgggtg
    30541 ttatcctcta ttccgttaat attcgagaca attgaaaaat acgagcgaat cattgtgccc
    30601 ttagtattca ttctacttgg actatacatc atgtatgaaa atggcacgat agagactttt
    30661 ctgatcgtgt agattttttt gtttcactag gattttagcc ctctgaaaat cagctctctg
    30721 attttcagag ggctttttca ttgagcataa atggacaatc ttaaagttac tctattgtag
    30781 agtggctttt gatttgatta ggagattctt ataaatatag taaaatgaaa taagaatagg
    30841 acaaatcgat caggacagtc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact
    30901 attctagttc caatctacta tataaatgaa aaccttagct gtttggccaa ggttcatttc
    30961 ttctatgcaa gttcttctct tttcttatct gggttccaga tgaagcttgc gataaagcta
    31021 aagatgatgg ttaggatagc gaggataata gcaaggatga gggcagggat gcggataaac
    31081 caccagagtg gatttggttt tttatcattg tgccattgtt tcgtttcttc gtccagacgt
    31141 tggaattctg tttgaatacg attggcgact gtttcaatgc cttcatcatt cattttcttg
    31201 atatctgaga tatcgattgg atttccaaag ttcatatcga cacgttcacg gctaatcaag
    31261 cccttcaaag tcatgggacc ggtgtaggta accggcatga tacggacctt ggccattttg
    31321 gcaatcagtg ctgcgccccc cttgacatcg tttgagtggc ggctaccact tggaaacatg
    31381 atgagagagc ggtcactttt tttgagaacg ttgataggat atttgatggc tgaggcgctg
    31441 ggattttcac ggtcgatggg aaaggcgcca cacatacgaa tccaccaacc aaagatacgg
    31501 ttggtaaaga gttctttttt tgccataaag atgaactgtt ttggcttggt cgcaaaggcc
    31561 atataaacag gatcccacca ggtacggtga ggcgcaacta aaatataatt ttcatcttga
    31621 ttaggaattt tatcagtatt atgatagtga gcattgccat tgatggacca taagagcaac
    31681 acaactaatc cacgcaaata agtataaaac atgcgatctc cttcgattgt tttcttgtta
    31741 ttattatacc ttatcaaagg agggctggca aacttttccc ttgactagat gcatatttag
    31801 gatgaaatta gaattctgtt aaaaaaaatg atataataga atttatggat aaaaataaga
    31861 ttatgggatt aacccaaaga gaagtcaagg aaagacaggc tgagggtttg gtcaatgact
    31921 ttaccgcatc agccagtacc agcacttggc aaatcgttaa acgaaatgtc tttacccttt
    31981 ttaacgcttt gaactttgcc attgctttgg cccttgcctt tgtgcaggct tggagcaatc
    32041 tggtcttctt tgctgttatc tgctttaacg ctttttctgg gattgtgacc gagctacgag
    32101 ccaaacacat ggtggacaag ctcaatctca tgaccaagga aaaggtcaaa accatccgtg
    32161 atggtcagga agtttctctt aatcctgaag aattagtgct aggagatgtc attcgtttgt
    32221 ctgcaggaga gcagattcct agtgatgcct tggttttgga aggctttgcg gaagtcaatg
    32281 aagccatgtt aacgggagaa agtgatttgg tgcaaaagga agttgacagc ttacttttgt
    32341 caggaagttt cttggctagt gggtcagttt tagctcgtgt ccatcatgta ggtgcagaca
    32401 actatgccgc caaacttatg ctggaagcca agaccgttaa acccatcaac tcacgtatca
    32461 tgaaatcgct ggacaagcta gcaggtttta ctgggaagat tatcattccc tttggtctgg
    32521 ctctcttgct ggaagccttg cttttaaaag gcctgcctct caagtcatct gttgtaaatt
    32581 cgtcgacagc ccttttggga atgttgccta agggaattgc ccttttgacc attacttcgc
    32641 tcttgactgc agtgattaag cttggcttga aaaaggtctt ggtgcaggag atgtactctg
    32701 ttgagacctt ggcgcgcgtg gatatgctct gtctggacaa gacgggtacc atcacccaag
    32761 gaaagatgca ggtggaggct gttcttccac tgacggaaac ttatggtgaa gaggctgttg
    32821 ccagcatcct gaccagctat atggcccata gtgaggataa aaatccaaca gctcaagcca
    32881 ttcgccagag attccaaggt caagtagtct atcctatgct ctctaatctt cccttctcca
    32941 gcgaccgcaa gtggggagcc atggagttag aaggtttggg aatagttttc ttaggggcac
    33001 ctgagatgtt gctggattct gaggtcccag aagccagaga ggccttggag agaggttcac
    33061 gtgtcttggt cttagctctc agtcaggaga aattagacca tcacaaacca cagaaaccat
    33121 ctgatattca ggctctagcc ttgctggaaa tcttggatcc tattcgagag ggagcggcag
    33181 agacgctgaa ctatctccgt tctcaggaag tggggctcaa gattatctct ggtgacaatc
    33241 cagttacggt atccagcatt gcccagaagg ctggttttgc ggactatcac agctatgtcg
    33301 attgttcaaa aatcacggat gaggaattga ttgctctggc ggaggagaca gcgattttcg
    33361 gacgtgtttc ccctcatcaa aagaaactca ttatccaaac gctgaaaaaa gcgggtcata
    33421 caacagctat gactggggat ggagttaatg atatcctggc tcttcgtgag gcggattgtt
    33481 ctatcgtaat ggcggaggga gacccggcaa cccgtcagat tgccaacctg gttctcttga
    33541 actcagactt taatgatgtt cctgagattc tttttgaagg tcgtcgtgtg gtcaataaca
    33601 ttgcccacat cgctccgatt ttcttgataa agaccatcta ctcattcttg ctcgcagtta
    33661 tctgtattgc cagtgcttta ctaggtcggt cagagtggat tttgattttc cccttcattc
    33721 cgatccagat taccatgatt gaccagtttg tggaaggttt cccaccattt gttctgactt
    33781 ttgagcgaaa tatcaaacct gttgagccaa atttcctcag aaaatccatg cttcgtgccc
    33841 taccaagtgc cctcatggtc gtgtttagcg ttctttttgt gaaaatcttt ggaacgagtc
    33901 aaggttggtc tgagttagaa atctcaactc tcctctatta tctcttgggg tcaattggtt
    33961 tcttatccgt atttagagcc tgcatgccat tcactctatg gcgagtcctc ttgattgtct
    34021 ggtcagtagg aggcttccta gccacagctc tcttcccaag aatccaaaaa ctgcttgaaa
    34081 ttgcaacctt gacagaacaa acgttgcctg tttatggtgt catgatgttg gtctttacag
    34141 tgattttcat cctgactagt cgctatcaag ctagaaaata aagaaagact gcaatctgtg
    34201 gattgcagtt ttttatacga tggatctatc gtagatctga tgtgcaaggc ctacgtgtct
    34261 attatctatc ggtgaaccca agagtgattc tcaagcctgc ttggattgag gtaatagatt
    34321 caaatatctg tagttagact atttgaagtt tgatgtaaga aagagaaagc gacagattga
    34381 agtaatttta actctcttct attgctagaa caaatggtcg gataggttgg tagtttgaaa
    34441 atgaagatgc aatctattgt taaatggaac atagtgttat ttattagaaa atcgtttggt
    34501 ttatttatta tcaaatacga aaagcaactt aaatatttca actaaaatag atgttatgaa
    34561 gaaaaggtaa aatgattttg gtatagtgag gttctgttct atttgatatc atatttttga
    34621 taaaaacaaa aatgtccatt gcaaaggaca aaatgcgaag tatattattt tttgaaagcg
    34681 atataatgga atcataaagg aggtgtatcg tgtctagaaa acaagaacaa atggaaacgt
    34741 tgttgctcct tttgcgagat agtaaggatt atatatctgc taaagtattg ggagaaaaat
    34801 taaattgctc tgataaaacg gtttatcgcc ttgtcaaggt aatcaacaaa gattgtccgg
    34861 tagaagcatt cattttatct gaaaaaggca gaggtttcaa attgaatcca agaagttccc
    34921 tcgtggacgt tgatgggaat tttacagagg cttttgatcc tgaagtaagg cgtgaaaaat
    34981 tactagaacg tctcttgttg actgctccta agccacattc tatttatgat ttaggagagg
    35041 aattctacgt aagcgagtca gtagtactaa aagatcgtca gatattacaa gagagtctag
    35101 caatttatgg gttagattta aaaatgagac aacgaaagct ttttattgat ggggatgagg
    35161 ctcaaattcg ttcagccatt ctaaatctac tgccaatgtt taatcagttg gatttagagc
    35221 aaattacaca gaataaggtt cagcctcttg acggagaact tgctcacttt tgtttgggat
    35281 tactgattac acttgagaga gaattggggg taaacattcc ctatccatat aatataaata
    35341 ttttctctca cctgtatatt tttatcagta ggaatcgtcg tagtactagt attcatgttg
    35401 tagcaccttc aaaacctact attgttgatg agaaaattta cagtgtctgt caaaaaatta
    35461 ttcaagaaat tgaacaatat tttaagatga aggttgatgc agttgagatt gactatcttt
    35521 atcaatacgt tgtatcttcg agattgcaaa aaccattttc ttccgggaag cttccttttt
    35581 ctcagcgagt tttagatgtc actcattact attttagccg tatgtgtatg gacaatagag
    35641 agattgaaac gacagatcct gactttgttg acttggcgag tcatatcagt cccttactga
    35701 ggagattaga taatagagta cagattaaga atagtctttt atcacaaatt cttttaacct
    35761 atcctaatct agttaaagag ttaacaacta tttctaaaga agtgagtcta gtatttggtt
    35821 ttgcgtcctt gagtctggac gagattggtt ttctagtctt atattttgca cggtttcaag
    35881 aaaagcgagc acgtcctcta aaaacagtag tgatgtgtac atcaggtgtc ggaacttcag
    35941 agcttttacg agcacgatta gaaaagcaat ttactgaatt ggatattatt gatgtagttg
    36001 cttatcatca attagatgag ctgataaatc tatatccaga tttagatttc attgtgacga
    36061 cggtagcttt gcaggaacca gcaagtgtcc cgtttgtcct agttagtgtt tttctaaccg
    36121 agggtgataa acaacgtctt caagcaaaaa ttcaggagat aaactatgaa taatctttcg
    36181 cttgtcctta tggatatatc tgttcaaaat cgtcaagaag cctacaaaga attagcaaat
    36241 caaatcagcc ttcttgtttc tgaagataca gaaaaaatag aagagcttct atattaccgt
    36301 gagagacagg gaagtataga ggttgctaaa ggtgttcttc taccacattg tgaaggaaac
    36361 tttcaacatc atgtcttagt gattactaga ttaaaatcac ctatcagaga atggtcgaag
    36421 gatatccagt gtgttgacct tattatcggt ttggccattg cagtatcaca ggacaagtca
    36481 tgtattaaaa cattgatgag aagactagca gatgaatcat tcataaatca attaaaacag
    36541 ttaacaaaag aagaattacg ggagataata tatggaaatc aaagatattc ttaatgtgag
    36601 tctgatccag acggatttac agatgcagag caaagaagag gtttttgagg cattagctca
    36661 actattggtt gagacgggtt atgtgtctga tagagaccaa tttatcgaag gtctgtatca
    36721 gagagaggca gaaggacaga ccggtattgg gaattatatt gctattcccc atagcaagag
    36781 ttctgctgtg gagaaggcgg gggtagtcat agctataaat cacaatgaga ttccttggga
    36841 gaccattgat gggaaagggg tcaaagtaat tgtactcttt gcagttggtg atgatacaga
    36901 agctgctagg gagcatttga agaccttatc actctttgct cgaaaacttg gtaatgacga
    36961 agttgttgcc aaattagttc gggctcagac atctgatgat gtgattgcag ctttttgtta
    37021 ataagaaaaa attttggagg gtatccgtat gaaaattgtt ggtgttgcag cttgtactgt
    37081 gggaattgcc cacacttata ttgcacagga aaaattagag aatgccgcaa aggtagctgg
    37141 acatgtgatt catgttgaga ctcaggggac aataggggta gaaaatgaat tgagtcaaga
    37201 gcagattgat gcagcggatg tagttatttt agcagttgat gttaagattt ctggtatgga
    37261 acgctttgag ggtaaaaaga ttatcaaggt tccaacagaa gtggcagtca aatctcccaa
    37321 taaactgatt gctaaagctg ttgagattgt tacgaaataa ctgaaaatat ttaaggagaa
    37381 aatatatgtt gaaacactta aacttaaaag gtcacttatt gacagccatt tcctatatga
    37441 ttccaattgt ttgtggtgca ggattcttag ttgccattgg tttagcaatg gggggtggtg
    37501 ttcctgacgc tcttgtagca ggaaaattca ctatctggga tgctttagca actatgggtg
    37561 gtaaagccct tggtctcttg ccagttgtta ttgctacagg tttgtcttac tcgattgctg
    37621 gtaagccagg gattgcacca ggttttgttg ttggtctaat tgccaattct gttggttcag
    37681 ggtttatcgg tggtatcttg ggaggttata tagctggttt cttggttcaa gcgattatta
    37741 aaaaggtcaa agtaccaaac tggattaaag gtttaatgcc aaccttgatt attccttttg
    37801 tagcctcttt ggtaagtagt ttgattatga tttatattat tggagcgcct atcgcagcct
    37861 ttaccaactg gttgacgagc ttattacaaa gcttgggaag tgcttcaaat ggtttgatgg
    37921 gggcagttat tggagttctc agtgctgttg actttggtgg cccacttaat aaaacagtct
    37981 atgcgtttgt gttgacttta caggctgaag gtgtgaaaga accattgact gctttgcaat
    38041 tggtgaatac tgctacacca gttggatttg gattggccta ttttatcgcg aaattactca
    38101 aaaaaaatat ctatactcaa gaggaaatcg aaacattgaa atcggctgtt cctatgggga
    38161 ttgtcaatat tgttgaaggt gtaattccga ttgttatgaa taacttggtt ccaggtctca
    38221 ttgcaacagg tatcggtggt gctgttggtg gtgctgtttc tttgacaatg ggtgctgatt
    38281 ctgccgtgcc atttggtgga gtgcttatgt taccaaccat gactcgtcca gtagctggta
    38341 tttgtgcttt gttagccaac attgtagtca caggacttgt ctacgcgatt ttgaaaaaac
    38401 caataaaaca tacagaacca gttatgactg ttgaagaaga gattgatttg tcagatattg
    38461 aaattttgta agagggtaac gatgtcaaga attgaatttt caccatcttt gatgaccatg
    38521 gatttggaca aattcaaaga gcagattact tttttgaatg ataaagtagc atcttatcat
    38581 atcgatatta tggatggcca ttttgttccc aatattacct tgtctccttg gttcattcaa
    38641 gaagttcaaa aaattagtga cacaccttta tcagttcatc tgatggtcac agacccaacc
    38701 ttttgggtag atcaagttct cgatttacaa tgtgagtata tttgtattca tgctgaagtt
    38761 ctgaatggtc ttgcttttcg tttgattgat aaaattcatg atgcaggtct aaaggctggt
    38821 gttgtcctta atcctgaaac acctgtttct acaatctttc cctacattga tttacttgac
    38881 aaagtaacta ttatgactgt agatccaggt tttgcaggac aacgtttttt ggagtctacc
    38941 ttgtataaaa tccaagaact ccgtcagctt agagttcaga atggttatca ctacatcatt
    39001 gagatggatg gttcttcgag tcgtaagact ttcaaacaaa ttgatgtggc aggaccagat
    39061 atttatgtta taggtcgcag tggattattt ggtttggatg acgatattgc caaagcctgg
    39121 gatatctgtt ctagagatta cgaagaaatg accggaaaaa caatgccaat caaataatgg
    39181 tttgagaaga aatttattag ttaggaggaa tatatgtcac tacaatcagt taacgccatt
    39241 cgttttcttg gcgtagatgc tattaacaaa tctaattctg gtcacccggg aatcgtcatg
    39301 ggtgctgcgc caatggctta tagcctattt acaaagcacc ttagaattac acctgagcag
    39361 ccaaactgga ttaaccgaga tcgctttatc ttgtctgcgg gtcatggatc aatgctactg
    39421 tatgctctct tgcatttaac agggtataac gatgtatcca tggacgagat taaaaatttc
    39481 cggcaatggg gatctaagac acctggtcat cctgaagtga cgcatacgtc tggtgtggat
    39541 gcgacatctg gtccgcttgg tcaggggatt tctactgccg ttggtttcgc ccaagcagag
    39601 cgttttttag ctgctaagta caacaaagat ggttttccta tttttgacca ttatacttat
    39661 gttatcgctg gagacggtga cttcatggaa ggagtgtctg cggaggcggc ttcttatgca
    39721 ggtcatcaag ctttagataa gcttatcgtc ctctacgact ccaacgatat ctgcttggat
    39781 ggtgagacca aagatacttt ctctgaaaat gttcgcgccc gttacgatgc ttatggttgg
    39841 catacagttc tggtagaaga tggaacagat ttagcagcaa tttctacagc aattgagacg
    39901 gccaagtttt ctggtaagcc gagtttgatt gaagtgaaaa cggtaattgg ttacggctca
    39961 cccaataaaa gtggtacaaa tgctgttcat ggtgcaccac taggagcaga agaaacagga
    40021 gcaactcgta agtttttggg atgggattac gatccatttg aagtaccaga ggaagtatat
    40081 tctgatttca agacaaatgt agcggatcgt ggtcaggagg catacgatgc ttgggctagt
    40141 ttggtgtctg attacaaggt tgcttatccc gaagttgcta gtgagattga cgctattgta
    40201 gctggaaaat cccctgtaac cattactgaa aaagacttcc ctgtctatga gaatggcttc
    40261 tctcaagcaa ctcgtaattc gtcccaagat gctattaata cagcagcagc agttttacca
    40321 accttcttag gtggatcggc agacttagct cactccaaca tgacctacat caaggcagat
    40381 ggcttacaag ataaatataa tccattaaac cgcaatattc agtttggggt acgtgaattt
    40441 gccatgggaa caatcctcaa tggaatggct cttcatggtg gtttacgagt ttatggcgga
    40501 accttctttg ttttctctga ctacatcaaa gctgctattc ggctatcagc cattcaggag
    40561 ttgcctgtaa cttatgtctt tacccatgat tcaattgccg ttggtgaaga tggtccaact
    40621 catgaaccag ttgaacattt ggcaggttta cgctcaatgc caaacttgac tgttatccgt
    40681 ccagcggatg cccgtgaaac tcaagcggct tggcatcatg ccttgaccag taccaccact
    40741 ccaactgtca ttgtcttaac ccgtcaaaac ttggtagttg aagaagggac agactttggt
    40801 aaggtcgcta aaggagccta cgtcgtgtat gataccccgg gatttgatac tattatcatt
    40861 gctacaggat ctgaggtcaa tctagctatc aaagctgcta aggaattggt tttacaaggt
    40921 ggtaaagtac gtgtggtatc tatgccctca accgaactat ttgatgctca agatgctacc
    40981 tacaaggaag acattttacc atctaagact cgtcgtcgtg tggccattga aatggcagcg
    41041 acccaaagtt ggtacaagta tgttggtttg gatggcgcgg tcatcggtat tgacatcttc
    41101 ggtgcgtctg ccccagctca gactgtgatt gataattatg gatttacggt agagaatatc
    41161 gttgctcaag ttaagtccct atagaaacca attacaatga agatacagct gttgtcagac
    41221 tagcagatgt agtgatagac actaatcaga tgattggtta tttaaaaact ataatgagaa
    41281 tgtaataatt tatctacgaa agttatagta gatagtatac acaatagagt ataccctgaa
    41341 acggttgcga agtacgctaa tcactttgct actgatctag atagtttctt taatcaataa
    41401 acacagcatc cacagattga cttaggatat tgtaagtttt ttgaaagcta gagagaaggt
    41461 ctctaaaatt aaaaaacgca tagtatagga tgttaaaatg aactgacccc aaaagttaga
    41521 cagaaaaaat ctaacttttt ggggtgtttt attatgaaat taagttatga tgataaagtt
    41581 cagatctatg aacttagaaa acaaggatat agcttagaga agctttcaaa taaatttggg
    41641 ataaacaatt ctaatattag gtacatgatt aaattgattg atcgttacgg aatagagttc
    41701 gtcaaaaaag ggaaaaatcg ttactattct cctgatttaa aacaagaaat gattaataaa
    41761 gtctgacatg aaggctggac taaagataga gtttctcttg aatacggcct cccaagtcgt
    41821 acgatacttc ttaactggct agcacaatac aggaaaaacg ggtatactat tgttgagaaa
    41881 acaagaggga gagtacctaa aatgggacgt aagccaaaaa cgagacctga agagaggaca
    41941 gaattagaac atcttcaagc agaaaatgag tacctgagag cggagaatgc catcctaaaa
    42001 aagttaagag aactccgatt gaaggaggaa aaagagaaag aagaaagaca gaaattgttc
    42061 aagaattaat gactgagttt tcgttagctc ttcttctaaa agccattaaa ctagctcgtt
    42121 cgacctacta ctatcacttg aaacagctag ataaaccaga taaggaccaa gagcttaaag
    42181 ctgaaattca atccattttt atcgaacaca agggaaatta tgcttatcgt cggatttatt
    42241 tagaactaag aaatcgtggt tatctggtaa atcataaaag agttcaaggc ttgatgaaag
    42301 tactcaattt acaagctaaa atgcgacaga aacgaaaata aaggagacgt tggtaagaag
    42361 gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa caatggaaca gtgctacaca
    42421 gatgtgacag aatttgccat tccagcaagt actcaaaagc tttacttatc accagtttta
    42481 gatggcttta acagcgaaat tatcgcctat aatctttcaa cttcacccaa cttagaacaa
    42541 gtacaaacaa tgttggaaca ggcattcaaa gagaagcact acgagaatac gattctccat
    42601 agtgaccaag gctggcaata ccgacacgat tcttatcatc ggttcctaga gagtaaggga
    42661 attcaagcat ccatgtcacg caagggaaac agccaagaca acggtatgat ggaatctttc
    42721 tttgggattc tgaaatcgga aatgttttac ggttatgaga agtcgtttca gtcgcttaag
    42781 caattggaac aagccattat agactatatt gattactaca acaataagag aattaaggta
    42841 aaactaaaag gacttagccc tgtgcaatac agaactaaat ccttcggata aattaattgt
    42901 ctaacttttg gggggcagta catttttggt atatataaaa tttgtaggag ctatatctac
    42961 aattttatat tcccagttta tggatgtcac ttactatatt cacaatgtta tccagtgttt
    43021 ttttctctaa tatttaagga gtgttctgtt tctcgaataa attcttcaaa gtttaacacg
    43081 tcaacttgtt cctgaacaag aaaataatca tccacgatat aaaattcatc agttaaatta
    43141 gtagtataac ttttatcggc taattttttt agcatgtgag cttcattttt tatatcatca
    43201 agagctgtcc attctccttc agcatcataa ttcacaaaag gtcttgactg cttgatgatt
    43261 actttttgcc cgtccgattt tctaattgcc cgataaacat ttcctttatt tgatctctta
    43321 ataatttttt ccattttgta tttatttatt gcagagtcct tgcttgaaac ttcacatgtg
    43381 gtttgaaaat aaatcctttt ttcttcttct gaaaataaat ccattttcca gctaggaaga
    43441 ctagggaaat tttgtctctt atcttctaca tagttcttcc ttttttcatc tagcaataaa
    43501 tagatgactt ttttattttt ttcatcataa gcttgttttt ttaaaaaagc tccatatcta
    43561 taatgaactg gagaatgcat tccacattga tagtcagata gtatttttgg agccttaaat
    43621 tctgacagtc tattcgtaag attacaaatc atactcttag cttcagattc tgacttagga
    43681 tatagagtta taaatttgtt agcagtaggg ctcatttccc taggggaatt aatttttttt
    43741 aattcctcta aatttttaac aactttaaag ctacaattat ttagttggga tagtttatac
    43801 acaatcttaa aaatatttac agcgtctttt atttgggagc ttatgtgtat tttccaccct
    43861 tgtgcaggca ccttatctga taaataatag taattccaaa tatcaccctg ttggaaattt
    43921 ttatcacatt ttaaacattc tttctctaat aaatccataa caaactccta attattaaaa
    43981 taggctagag acacagcact agcctattcc gtaagtaaag ctacttattt tatataaaat
    44041 ataactagcg acctgtaatt aaacaagtaa aagaacaata cttagggaga cctgtgacaa
    44101 tgatatcttc ctctggaagt agttctaatt caaacaatgt ttgttccatg actgtatcct
    44161 cctgttatga taaattccag aaagcataga gcaaattcgt ggttcgtctg actaaatttc
    44221 ttatctgaac accaccttca aatacaaatt ttagtcaaac ttttattttt tctaactttc
    44281 taattatatt ctaccatgtg cttttatatg tcaagaattt tctgaataaa ctgtttattt
    44341 tttatttttt gacatttttg caaattgttt aaaatctttc aattggattc acttattact
    44401 ttaggacatt gaaacttctt tcgccagagg tgcttatatt actgggaagt tgaagattga
    44461 aatgtggtat aataagaggt aatagagttt tggaaagtga gagaagatga tttcaaagag
    44521 attagaattg gtagcttcct ttgtgtcaca gggggctatt ttactagatg tgggaagtga
    44581 ccatgcttat ctgcctatcg agttggttga gagaggccaa atcaaaagcg ctattgcagg
    44641 tgaggtggtg gaaggtccct atcagtctgc ggttaaaaat gttgaggctc acggcctaaa
    44701 ggagaaaatc caagtccgtt tagccaatgg cttggcagct tttgaagaga ctgaccaagt
    44761 gtctgtcatt accattgctg gcatgggtgg tcgtttgatt gctaggattt tagaagaagg
    44821 tttggggaag ttagctaatg tagagcgttt gatcctccag cccaataatc gtgaagacga
    44881 cttgcgtatc tggctacagg atcatggatt ccagattgta gcagaaagca tcttagaaga
    44941 agctggaaag ttttatgaga ttttggtggt ggaagcagga caaatgaagc tatcagccag
    45001 tgatgttcgc tttggtccct tcttgtccaa agaagtcagt ccagtatttg tccaaaaatg
    45061 gcaaaaagaa gctgagaagc tagagttcgc cctcggacaa atcccagaaa aaaatctgga
    45121 agaacgtcaa gttctagtag ataagattca agctatcaag gaggtgctcc atgttagcaa
    45181 gtgaagtgat ccaagcttat gaagcctttt gccctcagga attttctatg gagggagaca
    45241 gccgtggtct gcaaattggc actttagaca agggtatcca aagggtcatg gttgccctcg
    45301 atattcgtga agagacagtg gcagaggcca ttgaaaaggg tgtggacttg attatcgtca
    45361 agcacgcgcc tatctttcgt cctatcaagg acttgcttgc cagccgtccg caaaatcaga
    45421 tttacatcga cctgattaag catgacatcg cagtttatgt cagccatacc aatattgata
    45481 tcgttgaaaa tgggctcaat gactggtttt gtcagatgct agaaatcgag gagacgactt
    45541 atctgcagga aacaggtcca gaacgtggaa ttggacgtat tgggaatatt cagcctcaga
    45601 cattttggga attggcccaa caggtcaagc aagtctttga cctagatagc cttcgaatgg
    45661 tgcattatca agagaatgat ttgcagaagc ctatttcaag agtagcaatt tgtggtggaa
    45721 gcgggcagtc tttctataag gatgctttgg caaagggggc agatgtctat atcactggtg
    45781 atatctacta ccatactgct caggatatgc tgtctgatgg cttgttagca ttggatccag
    45841 gtcactatat cgaagtgctt tttgtggaaa aaatcgcagc actccttact caatggaaag
    45901 agaaaaaagg ctgggaacta gagattttac ctagtcaagc atcgaccaat cctttccgtc
    45961 atatctagtt agaaagtgaa gacaatgaaa aaagttgcca ttattggagc aggaattgtg
    46021 ggagcaacag ctgcctacta cctctcgaga gaaagtgacc tagaggtgac cgtttttgac
    46081 catgagcaag gtcaagccac caaggccgca gcaggaatta tcagtccttg gttttccaaa
    46141 cgccgtaata aagcctggta caagatggcg cgcttggggg ctgattttta tgtggattta
    46201 ttagctgatt tagagaaatc aggacaaaaa atcgactttt accagcgttc gggagtcttt
    46261 ctcttgaaaa aggatgaatc caagttggaa gaactttatc aactggccct ccagcgcaga
    46321 gaagaatctc ccttgatagg gcaattagcc attctggacc aagcttcagc taatgaatta
    46381 ttccctggtt tgcagggatt tgaccgcctg ctctatgctt ctggtggagc gagagtagat
    46441 ggccaactct tggtaactcg tctgctagaa gccagtcatg tcaagctggt caaagaaaaa
    46501 gtgactctga caccgttagc atcaggctac cagattggtg aagaggagtt tgagcaggtt
    46561 attttggcga cgggagcttg gttgggggac atgttagatc ctttaggtta tgaagtagat
    46621 gttcgtcctc aaaaaggaca actacgagat tatcagctgg tccaagacat ggaagcttac
    46681 cctgttgtca tgccagaagg ggagtgggat ttgattcctt ttgcaggtgg gaaattgtcc
    46741 ttaggcgcta cccacgaaaa tgacatggga tttgatttga cggtagatga aaccttgctc
    46801 caacaaatgg aggaggcggc cttgcctcat tacccagttt tagctagagt gacttcaagg
    46861 gctgagcgtg tgggaatccg tgcctatacc agtgatttct ctcccttctt tgggcaggtg
    46921 ccagaattgg caggtgtcta tgcagccagt ggactaggtt catcaggcct cacaactggt
    46981 cctatcattg gttaccatct agcccaactg atccaagaca aggagttgac cttggaccct
    47041 ctaaattacc caattgaaaa ctatgtcaaa cgagtaaaaa gcgaataata ctcaatgaaa
    47101 atcaaagaac aaactaggaa actagccgcg ggttactcaa agcactgctt tgaggttgtg
    47161 gatagaactg acgaagtcag ctcaaaacac tgttttgagg ttgtagatag aactgacgaa
    47221 gtcagtaacc atacccatgg caaggcgacg ttgacgtggt ttgaattgga ttttcgaaga
    47281 gtataagcat tttactgaaa ttttatcagg tagtttagga tggcaaatga cattccctgt
    47341 caaaaatggt aaaataagaa aaaataatct gagaatcgag gaaaaaagat gcaagaaaag
    47401 attttggtaa ctggtggtgc cggttttatt ggaacccaca ctgttattga attgatccaa
    47461 gcaggccatc aagttgttgt ggtggataat cttgtcaata gcaatcgtaa gagtttagaa
    47521 gttgttgaaa gaatcacagg agttgagatt cctttctatg aggcagatat tcgtgacaca
    47581 gctaccctca gagatatttt caagcaggaa gaaccgactg gtgtcattca ctttgctggt
    47641 ttgaaggctg ttggcgaatc aacacgtatc cctcttgcct actatgacaa caatatcgct
    47701 ggaactgtca gccttttgaa agccatggaa gaaaacaact gtaaaaacat catcttcagt
    47761 tcttctgcga cagtttacgg ggatccgcac acagtgccca tcttggaaga tttcccactt
    47821 tcagtgacca acccatacgg tcgtactaag ctcatgctag aggaaatttt gactgatatt
    47881 tacaaagcag actcagaatg gaatgttgtc ttgcttcgtt actttaaccc aatcggagcc
    47941 catgagagtg gtgatttggg agaaaatcca aacggtattc caaacaatct cttgccatat
    48001 gtgactcaag tagccgttgg aaaattagag caagtgcaag tgtttggaga cgattacgat
    48061 acggaagatg gaacaggtgt tcgtgactat atccacgttg tcgatttggc taagggtcac
    48121 gttgcagctt tgaaaaaaat ccaaaaaggt tcaggactaa acgtttataa ccttggaact
    48181 ggtaaaggtt actcagttct tgaaattatc caaaacatgg aaaaagcggt gggacgtcct
    48241 attccttacc gtatcgtaga acgtcgccca ggtgatatcg ctgcctgcta ctcagaccca
    48301 gcaaaagcta aagcagaact cggttgggaa gcagaactcg acatcaccca aatgtgtgaa
    48361 gacgcatggc gttggcaaag caagcatcca aatggatttg aagactaaga tgatgatttc
    48421 aatcatcgtc ccttgtttaa acgaagagga agtacttcct cttttttatc aggctctgga
    48481 agctttactt ccagatttgg aaacagaaat cgagtatgtc tttgtcgatg atggatcaag
    48541 tgatgggacc ttggaactct taaaggccta tcgggagcaa aatccggcag tccattatat
    48601 ttctttctct cgaaattttg gcaaagaagc agccctttat gcaggcttgc aatatgcgac
    48661 aggagatttg gtggtggtga tggatgcaga cctccaagat cctcctagta tgttgtttga
    48721 gatgaaaaat gtactagaca aaaatgtaga cttggactgc gttgggacac ggagaactag
    48781 tcgggaggga gaacccttct ttcgcagttt ctgtgctgtt ctcttttatc gcctcatgca
    48841 aaaaatcagc ccagtggctc tgccgtcggg tgtccgtgat tttcgtatga tgagaaggtc
    48901 tgtagtcgat gccattttaa gcttgaccga gtccaatcgt ttttcaaagg ggctcttcgc
    48961 ctgggtgggt ttcaaaacct actatttgga ctatccaaat gtcgaaaggc aggctggcaa
    49021 gacaagttgg agttttagga aactcttttt ctactccatt gaagggatta ttaatttttc
    49081 agattttccc ttgattatag cctttgtagc tggtctccta tcttgttttc tttctctgct
    49141 gatgaccttt tttgttgtgg ttcggaccct cattttgggc aatccgacat ctggttggac
    49201 ctctctgatg gctgttattc tctttcttgg aggcattcaa ctcttgacca ttgggattct
    49261 cggcaagtat atcagtaaga tttatttaga gactaaaaaa agaccacttt atcttatcaa
    49321 agaaaaaagt gaccttcctg attttacaga aaaaaataaa gtgaaaagac tataatttta
    49381 catggaaatg tgctaaacta gagggagtgg attatcgcca ttgatttagg cttcctggtt
    49441 tccaatcagg gcgcgagttg ggcaattttt aacagcctct aagacatcct gactaggaga
    49501 aatttctttt tccagttggt cagggtcatc gtaaaaacgc acgattccat tatcgtggta
    49561 atcaaataaa tcagaataag tttggcaaag cccacaggcg atacatcgtt caggtataag
    49621 tgtgattttc atgttcatat ttatattgta ataagaaaag taaaaaaaaa caaggagtaa
    49681 ggtatggcaa aagaaccgtg gcaagaagat atctatgatc aagaagaatc aagagcagag
    49741 cgtcggcatc gaaaccacgg aggggctgat aggatggcta atcgtatttt gacgatccta
    49801 gctagtattt tctttgtaat tgtggtggtg atggtcatcg ttctcatcta tctatcatcg
    49861 gggggaagta atcgcacagc agccttaaaa gactttcatg attctgatgc aagtgtagta
    49921 caaatctcat cttcaagcag ttctcagcct gagcagagtt cagagccaga atctacttct
    49981 agtagttcag aagaagctgc taatcctgaa ggaacgatta aagttctcgc aggagaaggg
    50041 gaagcagcta ttgccgctcg tgcaggaatc tccattgctc agttagaggc cttgaatcct
    50101 gggcacatgg ctacaggatc ttggtttgct aatccaggtg atgttataaa aataaaatag
    50161 gagccgatat gaaaacaatt caaattgcta ttgatggtcc tgcttccagc ggtaagagta
    50221 cggtcgcaaa gattattgct aaggattttg gattcaccta ccttgataca ggagctatgt
    50281 atcgtgcagt gacctatatg gctcttaaga accaattagg agttgaagaa gtcgaagccc
    50341 ttctagcctt gttggaccag catccaatca gctttggacg ttcagaaact ggagaccagc
    50401 ttgtttttgt aggagatgtg gatattaccc atcctatccg tgaaaatgaa gtgaccaatc
    50461 atgtttctgc tattgcagca attcctcaag tgcgtgagaa actagtttct ctccaacaag
    50521 aaattgccca gcaaggcggg attgttatgg atggtcgcga tattggaact gttgtattgc
    50581 cgcaagcaga attgaaaatt ttcctagtag cttctgttga tgagagagca gagcgtcgtt
    50641 acaaggaaaa tattgccaag ggaattgaaa cagaccttga aaccctaaaa aaggaaattg
    50701 ctgcgcgtga ctacaaggat agtcatcgtg agacttctcc tctcaaacaa gcagaggatg
    50761 ctgtctacct tgatacaact ggtttgaaca ttcaagaagt agttgaaaaa atcaaagcag
    50821 aagctgaaaa aagaatgtaa atgtagaaaa gccgatagat tgatatcggt tttttctaaa
    50881 tttgtcaaaa tgctgatttt agggtataat agttgctgtt cgagaaattt tgattttcaa
    50941 agaatagtga atgatgataa ggagaaatca tgaacaattt accaaattgt ccaaaatgta
    51001 actcagagta tgtctacgaa gacggtgccc tactggtttg cccagagtgt gctcatgagt
    51061 ggaatcctgc tgaagttgca gaagtagaag aaggtcttgt cgctatcgat gccaacggaa
    51121 ataaattggc tgatggtgat acagtaactc tcatcaagga cttgaaagta aaaggtgcgc
    51181 caaaagattt gaaacaaggg acgcgcgtga aaaatatccg catcgtagaa ggcgaccaca
    51241 atatcgactg taagattgat ggttttggtg ccatgaaact taaatcagag tttgtgagga
    51301 agatttaagc atgtcaaaac actataaact tgtattttat agccgtatct tcttgtttct
    51361 agcggctttt acgggagttt atcttgaaat tactaggcat ggtggttttg ggatgcttct
    51421 ctattacacg gttctgtcca acctcttggt aactattttt accctttatc ttctaaaggt
    51481 tatgagccgt gtaggtgaaa attggcaaag gccaagtctc ttgcgcttaa aaggtggggt
    51541 caccatgagt atcatgatta cctgtgtgat ttaccatttc ctcttggcgc ccattgcgac
    51601 taatttctat accctagaaa atttcctttg ccactatatc gttcccatct ggtttttagc
    51661 ggataccctc ttttttgaca aacagggtca atacaagatt tgggatccag cagtgtggac
    51721 cattttaccc tttctgtata tgatgtttgc tctttttaat ggcttggttc taaaactcaa
    51781 tattccaaat gccaaggata atcctttccc ttacttcttt ttgaatgtga acaagggttg
    51841 gaatgttgtg tttaagtggt gtctgattat ctttgttgcc tatatggtag caggatttat
    51901 tttctacttt atcaagcaaa tcaagagaaa gtcatcctaa tactcttcga aaatctcttc
    51961 aaaccacgtc agtttccatc tgcaacctca aaac
//
LOCUS       DAVHSI010000015        48114 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.015, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000015 DAVHSI010000000
VERSION     DAVHSI010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48114
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.015"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            48..323
                     /locus_tag="VVR21_000942"
                     /pseudo
     CDS             48..323
                     /locus_tag="VVR21_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1049..1309)
                     /locus_tag="VVR21_000943"
     CDS             complement(1049..1309)
                     /locus_tag="VVR21_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054845.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1368..1919)
                     /locus_tag="VVR21_000944"
     CDS             complement(1368..1919)
                     /locus_tag="VVR21_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054846.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLNEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLRLAS"
     gene            complement(1909..2106)
                     /locus_tag="VVR21_000945"
     CDS             complement(1909..2106)
                     /locus_tag="VVR21_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054847.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEKSEALENMILQYLGEDDAS"
     gene            complement(2110..2694)
                     /locus_tag="VVR21_000946"
     CDS             complement(2110..2694)
                     /locus_tag="VVR21_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054848.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(3102..3527)
                     /locus_tag="VVR21_000947"
     CDS             complement(3102..3527)
                     /locus_tag="VVR21_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054849.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3656..4039)
                     /locus_tag="VVR21_000948"
     CDS             complement(3656..4039)
                     /locus_tag="VVR21_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054850.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKETVLG"
     gene            complement(4061..4267)
                     /locus_tag="VVR21_000949"
     CDS             complement(4061..4267)
                     /locus_tag="VVR21_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054851.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(4254..4415)
                     /locus_tag="VVR21_000950"
     CDS             complement(4254..4415)
                     /locus_tag="VVR21_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054852.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4774..5730)
                     /gene="lytA"
                     /locus_tag="VVR21_000951"
     CDS             complement(4774..5730)
                     /gene="lytA"
                     /locus_tag="VVR21_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU6054853.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(6106..7476)
                     /locus_tag="VVR21_000952"
     CDS             complement(6106..7476)
                     /locus_tag="VVR21_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6054854.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVFFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(7783..8949)
                     /gene="recA"
                     /locus_tag="VVR21_000953"
     CDS             complement(7783..8949)
                     /gene="recA"
                     /locus_tag="VVR21_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU6054855.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(9004..10260)
                     /locus_tag="VVR21_000954"
     CDS             complement(9004..10260)
                     /locus_tag="VVR21_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU6054856.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(10345..11361)
                     /locus_tag="VVR21_000955"
     CDS             complement(10345..11361)
                     /locus_tag="VVR21_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU6054857.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(11369..11887)
                     /locus_tag="VVR21_000956"
     CDS             complement(11369..11887)
                     /locus_tag="VVR21_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054858.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(11877..12320)
                     /gene="tsaE"
                     /locus_tag="VVR21_000957"
     CDS             complement(11877..12320)
                     /gene="tsaE"
                     /locus_tag="VVR21_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU6054859.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(12407..13027)
                     /locus_tag="VVR21_000958"
     CDS             complement(12407..13027)
                     /locus_tag="VVR21_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054860.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(13410..14273)
                     /locus_tag="VVR21_000959"
     CDS             complement(13410..14273)
                     /locus_tag="VVR21_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054861.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDLYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDAV"
     gene            14777..16792
                     /locus_tag="VVR21_000960"
     CDS             14777..16792
                     /locus_tag="VVR21_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6054862.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            16794..17426
                     /locus_tag="VVR21_000961"
     CDS             16794..17426
                     /locus_tag="VVR21_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054863.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            17567..17845
                     /locus_tag="VVR21_000962"
     CDS             17567..17845
                     /locus_tag="VVR21_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HEU6054864.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(18354..18767)
                     /gene="ndk"
                     /locus_tag="VVR21_000963"
     CDS             complement(18354..18767)
                     /gene="ndk"
                     /locus_tag="VVR21_000963"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU6054865.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(18878..22555)
                     /gene="rpoC"
                     /locus_tag="VVR21_000964"
     CDS             complement(18878..22555)
                     /gene="rpoC"
                     /locus_tag="VVR21_000964"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU6054866.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(22588..26199)
                     /gene="rpoB"
                     /locus_tag="VVR21_000965"
     CDS             complement(22588..26199)
                     /gene="rpoB"
                     /locus_tag="VVR21_000965"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6054867.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTKEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            26615..26685
                     /locus_tag="VVR21_000966"
     tRNA            26615..26685
                     /locus_tag="VVR21_000966"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26647..26649,aa:Cys,seq:gca)
     gene            complement(26883..28214)
                     /locus_tag="VVR21_000967"
     CDS             complement(26883..28214)
                     /locus_tag="VVR21_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU6054868.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(28443..29267)
                     /gene="endA"
                     /locus_tag="VVR21_000968"
     CDS             complement(28443..29267)
                     /gene="endA"
                     /locus_tag="VVR21_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU6054869.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(29306..29494)
                     /locus_tag="VVR21_000969"
     CDS             complement(29306..29494)
                     /locus_tag="VVR21_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU6054870.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(29487..30770)
                     /gene="murA"
                     /locus_tag="VVR21_000970"
     CDS             complement(29487..30770)
                     /gene="murA"
                     /locus_tag="VVR21_000970"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU6054871.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(30794..31024)
                     /locus_tag="VVR21_000971"
     CDS             complement(30794..31024)
                     /locus_tag="VVR21_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU6054872.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(31082..32119)
                     /locus_tag="VVR21_000972"
     CDS             complement(31082..32119)
                     /locus_tag="VVR21_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU6054873.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFLRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(32103..32591)
                     /gene="coaD"
                     /locus_tag="VVR21_000973"
     CDS             complement(32103..32591)
                     /gene="coaD"
                     /locus_tag="VVR21_000973"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU6054874.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(32581..33120)
                     /gene="rsmD"
                     /locus_tag="VVR21_000974"
     CDS             complement(32581..33120)
                     /gene="rsmD"
                     /locus_tag="VVR21_000974"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU6054875.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLIFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(33185..34177)
                     /locus_tag="VVR21_000975"
     CDS             complement(33185..34177)
                     /locus_tag="VVR21_000975"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU6054876.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(34289..34972)
                     /locus_tag="VVR21_000976"
     CDS             complement(34289..34972)
                     /locus_tag="VVR21_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU6054877.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(35028..35768)
                     /locus_tag="VVR21_000977"
     CDS             complement(35028..35768)
                     /locus_tag="VVR21_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU6054878.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            35802..36080
                     /locus_tag="VVR21_000978"
     CDS             35802..36080
                     /locus_tag="VVR21_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU6054879.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            36158..37084
                     /gene="yidC"
                     /locus_tag="VVR21_000979"
     CDS             36158..37084
                     /gene="yidC"
                     /locus_tag="VVR21_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6054880.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(37159..37953)
                     /gene="pflA"
                     /locus_tag="VVR21_000980"
     CDS             complement(37159..37953)
                     /gene="pflA"
                     /locus_tag="VVR21_000980"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU6054881.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(38079..39329)
                     /locus_tag="VVR21_000981"
     CDS             complement(38079..39329)
                     /locus_tag="VVR21_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU6054882.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTSD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(39396..40223)
                     /gene="purR"
                     /locus_tag="VVR21_000982"
     CDS             complement(39396..40223)
                     /gene="purR"
                     /locus_tag="VVR21_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU6054883.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(40490..41431)
                     /locus_tag="VVR21_000983"
     CDS             complement(40490..41431)
                     /locus_tag="VVR21_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU6054884.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(41421..42677)
                     /locus_tag="VVR21_000984"
     CDS             complement(41421..42677)
                     /locus_tag="VVR21_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU6054885.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(42679..43341)
                     /locus_tag="VVR21_000985"
     CDS             complement(42679..43341)
                     /locus_tag="VVR21_000985"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU6054886.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(43304..43960)
                     /locus_tag="VVR21_000986"
     CDS             complement(43304..43960)
                     /locus_tag="VVR21_000986"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU6054887.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(43971..44849)
                     /gene="rsgA"
                     /locus_tag="VVR21_000987"
     CDS             complement(43971..44849)
                     /gene="rsgA"
                     /locus_tag="VVR21_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU6054888.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(44851..45723)
                     /gene="rsmA"
                     /locus_tag="VVR21_000988"
     CDS             complement(44851..45723)
                     /gene="rsmA"
                     /locus_tag="VVR21_000988"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU6054889.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(45974..46267)
                     /locus_tag="VVR21_000989"
     CDS             complement(45974..46267)
                     /locus_tag="VVR21_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054890.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQILVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(46260..46901)
                     /locus_tag="VVR21_000990"
     CDS             complement(46260..46901)
                     /locus_tag="VVR21_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054891.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLEKQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(46903..>48114)
                     /locus_tag="VVR21_000991"
     CDS             complement(46903..>48114)
                     /locus_tag="VVR21_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6054892.1"
                     /translation="KGKLPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERA
                     SNKWSQSSDRYRLSFGWSSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFS
                     DGAEVDLDGNRLSDYTPSGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPE
                     SLREQSTYYQRLFTDYLQNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTT
                     RQYLKDPIIVVLTPQATGTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSY
                     LVKSQLFFAKVLNDKRVEFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLA
                     GMTIYELHGKYLLAQGGVLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKE
                     EAGSMAVLKGK"
BASE COUNT        14018 a        10752 c         8956 g        14388 t
ORIGIN      
        1 tgaagagatg ttagctgtat taaaaacagc ttatcaaaaa agtcagacaa gctggtaaaa
       61 tcttggctga cagtggttat caagggctca tgaagatata tcctcaagca caaactccac
      121 gtaaatccag caaactcaag ccgctaacaa ttgaagataa agcctgtaac catgcgctat
      181 ctaaggagag aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt
      241 caacaaccta tcgaaatcat cgtaaacgct tcggattacg aataaatttg attgctggta
      301 ttatcaatca tgaactagga ttttggtttc gcaggaagtc tattatatat gcacagacat
      361 atgaaatctt tttgagacag cagttatgat atatttatcc attcacaaca tcttctgtac
      421 caatactaca atattggtac attttgatta cacaatcgtt tcaaaaaata tgatggaagc
      481 ctgagtattt tatagtaatt cccttcctat caactagatc aaccagttga gtgttgaatg
      541 ttgaaacacc ctagcctcag caaaggacta tgatcagcat ttcctagcca ataggacgct
      601 ccaaatcacc tattctaagt ccatcactag cttggtcagt aagatacaga ctgcaaggca
      661 agactgacgt ggttgatgag attttggaag agtattacaa tcatagatta accagtagac
      721 ttgaccgtag attgaaacta gaatagtaca cctctgcttc taaaacattg ttagaaatcg
      781 atttgactgt cctgaacaat ttgtcctgtt ctcgtttcat tttactatac taaaaaacca
      841 cctgaaacaa atcaagtgac tagaggataa aaacaaagac tgggcaaaaa gttttgaaaa
      901 gcaaaaaacg cataatatca ggtcttgaaa aaccttgata ctatacgttt gattgtggga
      961 agattgactt cattttctcc tgaaattgaa gttttttcta gtttccagat ataaacgaat
     1021 tcaatatagc catctcgcta caattatttt aaccatcgag aaaatttttc agaatttcaa
     1081 aaatttcatt ttgatccaat gaaatgtcat cattttgaag aatagttgac ttcacaggct
     1141 ctaattctat cacaaagcgg tgcatgtctg cttttaccgc actacttgat gttatagccg
     1201 ataacttttc atctcctagc aaggaagctg tcaaacgggt aatgtcattc aaatgctttt
     1261 taatggactt acttaaacct tgagcacctg tagcagagcg ttccctcata tccagccaag
     1321 ctttagcctt aaaaataatt aatactcaat gaaaatcaaa gagcaaacta ggaagctagc
     1381 cgcaggctgc tcaaaacact gttttgaggt tgtagatgga agctgacgtg gtttgaagag
     1441 attttcgaag agtatagacc acaattactc aataccgaat acccctgaat ggtttctttt
     1501 tcatgcacca atatattata ataatcttca ttcaataata aggctgataa actagcatct
     1561 tggtcaaaat gtaagggaat ttctcgaccg tccttcttta atggatattc tggtaagata
     1621 ctaaatagtt caatcataga aggaaactca ggattagttg ttgtaaatcg aaaaagctgc
     1681 gctttctcat ctttctgact tccttgatac tctcccaatt ctaaaaaatg attcaaggta
     1741 gtataaaatt ccttattttt tacttcatca atgatgacca tatcataatc ttttgttgtg
     1801 cgacttttaa atccttgcga atccaatacg atagaggtag cagttccccc aatcagaaca
     1861 taatagttct gaaaatccgc aaacatttct tgaaaaataa ctttcgtatt agctggcatc
     1921 atcttctccc agatactgta atatcatatt ttctagtgct tcactctttt cctctatacg
     1981 tgggtcatca tcatctttta aggtcaaata aagagaaatc ggatctacaa attgtttatc
     2041 atgattattt ttaaaatcat tccaaaactc agatacaaaa ggacgatatt tccatatctc
     2101 tagcatcttt cattttaaaa catgctgaga aagtggcaag gataactgat tgaattttct
     2161 ctgccatatg acatagctag tattttcatc cgtttcagct aaaaaagttg aatgcgacaa
     2221 agcataagca ccaccatata gaaggttaga aacagatttt atctgcttta tatcgccatc
     2281 tggcaataaa aaggcaatcc acgttaattg ttcgctaggt gttaattcct tagggacttc
     2341 agtatcattc gcattcagta ctagtcccaa tgtagggaag aagaggtttc ccttaaagtc
     2401 tacaaacgga actctagctt gaagtaattg ctttttttca ccgtctgata acttcgaaaa
     2461 caccaaaaca acatccatat tggctttatc acccatagtg cgagcttgag taacaaatga
     2521 actcaaactc ccccttctct tttctttaat caataaaaat gattccttat gaaaagtcat
     2581 ttgagtatac tcaaaccttt ttacaaaact gattggtaaa gtcaaagtca gttcctcaat
     2641 actgacatca acataaaagg attgaaaaat tgacattatc tttttgacat tcatgttttt
     2701 tccttattct atcattttta ttatatttta tcattcggta taataaaata taagtttttt
     2761 gataaaataa ccaaaaacta ctccctatcc cctctcacac taccctacat atcgtttgac
     2821 atgcgactga tagttcagga aaacttcaag gagaactttt ctctcatcca ctatgcagga
     2881 cttactattt cacttctact cctataggct caatttgaca cttttctttt tcgaattgct
     2941 catatgcctc ctgaatagtg agttcgattt atccaaattt atttttgtct attttgatga
     3001 atacttccac gaagatagtc tgaaaatgaa tttgcaccaa ttttccttct ctttttaagc
     3061 atattattcc agatatgatt gccctcttgt tcagtaataa attacgcttt aaacgcttca
     3121 atcagtatat ctcctgttgt catatgttct aaagaaaatt cttctacata tggtttaaca
     3181 tctcttaggt tattacttcc taatatccca ttatgctttt tcgctaagaa aatagaagtc
     3241 gcttctccct taccaataat cttgttacta tcatgatttc ttgttaaatc tctatataat
     3301 gcgtattctt cagttccaat gtctatgctc acaatctcag ctgaaccctt agttaccaac
     3361 tggtctatcc tagattttaa atggggaatt gtaggtatat tgatttcatc gtacacctct
     3421 tgtggaataa caattttacc cgaatagagc ttttctaaaa gatgttcagt accaacccat
     3481 aaaaatactg aaatacaatc tgcatcaata aatacacgac tagtcaaacg acaactcccc
     3541 cctcttcata tagcccatat acaatatcat atctgaaagc atctagtaac agttcctcat
     3601 acttcccttg cgaaattctg ttattttcta aaagttgttc agttgaatta atatattatc
     3661 ctaataccgt ttccttttta ctttctgaca aaggacgata taaacttgta tcatagccta
     3721 atcttgaagc tgtctctata acactaatat ccatattttt aatttcttct gcatcaaggt
     3781 atccatcatt cctcaatcta tataacatag ctttatgact gataccataa aactgaccca
     3841 attttataat atcttctact tcaagatgag ttctattggc attttctctg atttcctcaa
     3901 ccatcctata cagtgaagat gggaaaatta aaaaataaga agcaaactga tccgcttttc
     3961 tttcagtttc atctccttca ccaatcaaga taagactgac tgaactcttc ttcacctcat
     4021 cataataaag atgatacagt tcatgtgcta aagaaaatct ttaccttcct aatgacatgt
     4081 ctgaattgac tgcaatgaga ctgaactgag ttcctttata acagactccg ctaatattct
     4141 ttccgagtcc ataaaatacc agcgtcaaat tttctatctt ttgtaccaat ttaaaaatat
     4201 ctatcggcga ttcaccatca gctcccaact tttttctaag atttggagct ttattactta
     4261 aatccattcg tgatattcct ttcacctttt tccattttgg caatcatgct ttgattcaaa
     4321 gacaaatact cagcaatctt atcttgagta agatttgaag atattctaag ttcttttatt
     4381 ctttttccaa catcacatac atttatcaca tacatttatc atattcatac acctctcata
     4441 aaaagaatag cacactcttg tcataatttt ttaaataaaa aaattatgac aaaacaagga
     4501 agcaatttat tgatgctgct taaaaatcta aaattgatga gttcctatca aaaatcgtat
     4561 cttcaacctc aaaacagtac ttaaagctat ccgactcggt ttacattgtc aaatttagat
     4621 tttatttgag cataactttc tagtttgctt tctgattttt gtttaatata gtagcaaaca
     4681 ttgaaggaaa tatctccaca aaaaaacgca tactattaag ctttttcaag acctaataat
     4741 atgcgctgtt ctgatttgaa agacattcca ttattatttt actgtaatca agccatctgg
     4801 ctctactgtg aattctggct tgtctgccag tgttccgtct ggtttgaggt agtaccagcc
     4861 tgttccgtcc gctgactgga taaaggcatt tgataccatg gcgccttctt tagcgtctaa
     4921 gtagtaccaa gtgtccttgt acttgaccca gcctgtcttc atggcacctt cttcgttgaa
     4981 atagtaccac ttatcagcaa ttttcttcca gcctgtagcc atttcgcctg agttgtcgaa
     5041 ccagtaccag ttgccgtctg tgtgcttcct ccagcggtct gcaagcatat agcctgaact
     5101 gtcaaagtag taccaagtgc cattgatttt ctcaaacttg tcttttggat aagagccgtc
     5161 tgaatgtacg taccagtagc cagtgtcatt cttctgccag cctgtttcaa tcgtcaagcc
     5221 gttctcaata tcatgcttaa actgctcacg gctaatgccc catttagcaa gatatggata
     5281 agggtcaacg tggtctgagt ggttgtttgg ttggttattc gtgcaatact cgtgcgtttt
     5341 aattccagct aaactccctg tatcaagcgt tttcggcaaa cctgcttcat ctgctagatt
     5401 gcgtaagagt tcgatataaa ggcggtagtc cgtcatgaac tcttctttag ttgaatggct
     5461 ttcaatcagt tcaaccgctg cataggtctc agcattccaa ccgcccccaa cgtcccaggc
     5521 accattatca acaggtccta cctgcatgat gcaaccgttc ccaacaatgt gcgagaaaaa
     5581 acctaattct gggtctttcc gccagtgata atccgcttca ttctgtacgg ttgaatgcgg
     5641 attcccagtt gagtgtgcgt gtacttgcct atatggttgc acgccgactt gaggcaaatc
     5701 tgttcttaat ttactcacat taatttccat attctactcc ttatcaatta aaacaactca
     5761 ttttttacaa tccagaacca gaaactcctt tatttctacc ttacaaagaa gacaatctta
     5821 gtcacgatta ggcttgtaga tagaacctca aaacgcacta ttttgacact gtaaatagga
     5881 ctgacaaggt ctgcattcta tctacaataa caccccagac taaaaagctt ttcaaaagta
     5941 tatttttaca gtctctatat gtccttttca taaatactat actttattat atcatataaa
     6001 agaagtcaaa agtctgttaa actattttca acaccaaact aaagaagaga acacaagttt
     6061 tttcgatgtt cactagagga aatggatttt attcagtaaa tccaactagg attgcacttt
     6121 ggttgccaaa attgcctttc cttcttttat caagggatga cggaatagtg agaagtacag
     6181 ttgaactgtc atggcaaccc agataagagg ttcacaaagg ataacaccct tatatcctgc
     6241 ccaaggaata atcaaaacca caaaaacgat ttttccgatt agttcaataa agctagaaac
     6301 tagaggaagg atcttctgcc ccaagccctg caagcaattg cgataaatca acaagaggct
     6361 caaaatggga taaaaggctg aactgatttg cagatagaga cttccatttt ctatcaagta
     6421 accatctgtc gaactagcca agaagaaaac caaagctgga ctggcaaaaa agaggaaaat
     6481 acaaacaaaa actgcccagg atatacttaa acgactgccg attcgaagac cttgaacaat
     6541 gcggtcaggt cgcttagctc ctagattctg agaagcaaag gtcgtcattg atgcagaaat
     6601 agcggtcata ggaagaaggg caaaggtcat aatgcgtcga gctgccgtct gggcactaat
     6661 aatcactgca ccaaatgtat taacagaaaa ctgtaaaatc acactgccga tagatacaat
     6721 tgaactcatc aagcccatag ccaaaccttg ctccaagaga tccgcgtaca agcttttgtc
     6781 ccatttgaaa tgtttaaact gtggcaagag ttctggcaca cttttacgaa tataataaaa
     6841 gcagagaacc gctgataaac cttgcgaaat aatggtagca agtcctgcgg attgaactcc
     6901 cagatgcaat tgcgtaataa aatagagatc cagaaccaca ttaaccaagg cagagaaaat
     6961 cagaaatccc agggctgcta gactgtcacc aatagaccgc aacaagcctg caaaaagatt
     7021 ataagcaaag ctgacaccta cacaggtcac aatcatagaa atatattgat aagattgagg
     7081 aagaatttct gcaggagtat ctaagtattg caagagagga tacaaaccaa gaaagcccag
     7141 caacataact agaatgctca aaagagcacc taaaatccaa gtggctgcta ctgcttcctt
     7201 gattttagtg aaattccgag ctccataata acgagcaatg acaatcccca tgccattgcc
     7261 aacaccaagt gtaaaaccta caatcaggtc aaaaatcgct gtcgtcgctc ctactgcagc
     7321 caaggattct tgaccaagaa atcgtccaac aatcaagaca tcagcagtgt tatagagctg
     7381 ttgaaaaata tttgatagca agattggaaa ggtgaagctt aagagcgagg gaagaatcgg
     7441 accatgtatc aggtccactg ttcgtttttt attcataaag ctattatatc agcttcctag
     7501 aggagcgaca agaaacagca aacttatata tagcggaatg aaataaggaa agtcaaatcg
     7561 atttttaaca atgttttaga agtagatgtg tactattcta gtttcgatct attatagttg
     7621 gttgagtttg gaatagtacg ctgtagctgc taaaacattt ctagaaatta atttgacttt
     7681 cctaataaag ttgttcatat cttatttcaa gctactatat ataatctaaa aacttgaatc
     7741 aaaaatcgaa aaagtagcgg atttctccac tgctttaaca gcttattctt caatttcgat
     7801 ttcaagttca tcgcctaagt caagcgtaac ttcttcattc actgcttctt ctttctttgg
     7861 ctcatctttt ttgttttcag tatcttgttc tgaaacttct tctccatcaa tcaagccaaa
     7921 tttagaacgg acttgcttat caatttcatc aaagatttct gggtgctctg ccaagtattt
     7981 cttagcattt tcagaacctt gcccaatttt ttcatctttg taagaatacc aagcccctgc
     8041 ttttttgata atatccaaat cgcttgcaat cttcaaaagc tcaccagtct tagaaattcc
     8101 ttctccgtac ataatttcaa ctacggcttc cttaaacggt ggagctacct tattttttac
     8161 aaccttaatc ttagtttctt taccgacatt ggtttctttt tggtcaccag ttcccttaat
     8221 ttgtgtatta ccacgaacat ccaagcggac tgaagcatag aatttcaaag cacgtccgcc
     8281 cggtgttgtt tctggatttc caaacatcac tccaactttt tcacgcaatt ggttgataaa
     8341 aatggcaatt gttttggttt tattgataga ggcgccaagt ttacgcatgg cctggctcat
     8401 catacgagcc tgcaaaccaa catggctatc tccgatatct ccatcaattt ccgcacgagg
     8461 aacaagggca gcaactgagt cgactacgac aagatcaact gcacctgagt caatcaattt
     8521 tcccgcaatc tcaagacctt gctctcctga gtctggttga gacaagagca attcgtcaat
     8581 attgacacca agggccgcag cataagctgg atcaagggca tgttccgcat cgataaaggc
     8641 agcaatccca ccttcttttt gcgcttgtgc aactgcatga agggcaaccg ttgtcttacc
     8701 agatgactct gggccataga tttcgatgat acgtccctta ggataaccac ctgagccaag
     8761 ggcaatgtca agagctaaag aacctgagct catcacttgc accttttgct ccgcacgttc
     8821 acccaaacgc atgattgatc ctttaccaaa gtctttctca atcaatttaa gagcgtcatt
     8881 caaggccttt tcacgttctg ccccaaattt ttttgaaatt tcttctaatt tttttggttt
     8941 tttcgccatt ctattctcct acattctaat gatcctcaga cctatctact attatatcaa
     9001 aagttagtca cttaataaag ccttgcgaac taggttaaag gcatgcataa ccgcaatatg
     9061 acgtacatct gctcggcttc tgcctccaat attaaccttg ataacctcag ttccttgctc
     9121 ttgcgccaag cctatgaaga ctgtcccaac tgggtgtcct tctaggctat ctggtcctgc
     9181 cactccggtc aaactaattc caaaatcaga ctgggtcttg cttcgtgcct gctcagccat
     9241 cttctgagct gtaaattcag acaccacacc atgttcttcc aaattcttgg caggaatatc
     9301 caacatcctt gatttttcct ccaagctata ggtcacaaaa ccacccttaa atatacttga
     9361 agctccagaa aaattcgcca cggtagcttg gaaaagacct gccgtcaaac tctctgcagc
     9421 cgcgatggtt ttcccttgcc ttttcagttc ttctaccaca atgctggcta aactagtttc
     9481 ttccccataa ccatagcaaa agtctcgtaa agaaattcct tcgaaagtct ggcagtccaa
     9541 gatttgattt tccaagatat ccagcgcttg attcgcctct tcttgactgc tagcctttgt
     9601 tgacagacgt agagtgactt ctcctgtctt ggcataaggg gccaaggtag gatcgatctg
     9661 attatcaatt aaatcagcca aaatcgtaac caactggctc tcgccaatcc caaagaaacg
     9721 aagaactcgg gaatacagct tgctccctgt catcaacttg ggtagaagtt ggtttaagac
     9781 catgggtttc aattcacttg gcggacctgg aaggacgaca taggtcactc cgtctacttc
     9841 taattttcct ccaacagcca gtcctgtttc gtttggcagt ggaatcgctc cttctacaat
     9901 ttgagcttgt ctttcgttat tcggtgttcg ggcatagtct ggtcgcaggg caaaaaagat
     9961 atccaacttc tcctgagcct gaggatcaaa gactaatgct ttccctaaaa atttagctag
    10021 ggtttgtttg gttaggtcgt cctcagttgg ccccaaaccg cctgtcaaaa tcaccagact
    10081 gctacgttga ctggcaatct caagcaaaga caagagacga acttcattgt ctcctacagc
    10141 cgtctgaaaa tatacatcta ccccaatctc agctagtttt tccgacaaaa actgggcatt
    10201 ggtgttgaca atctgccctg tcaaaatctc tgttccaaca gcaatgattt ctgctttcat
    10261 gtttcctcct acctatctat tcgtattttt ttgaaaaaat cgcaggaatt ttcctacgat
    10321 tgattttttt atttgtatca aaagttaatt atcttcatca ccaacaggtg ctctgccaaa
    10381 taaatcttca aataaaaccg cattggtttc aagctgagta acttcttctt gtcccaaaga
    10441 acgtcggagt atattttgca tttccaacat atgtgctctc gaaacaatct ggtaagaaac
    10501 accttgaagt atctctcctt caccctgcaa ctgctgagtt tcaatggttt taaatgaatc
    10561 tttatagcct agcaagttag ggatactttt tgcagacaaa tcaatattgg tctgcatatt
    10621 gtcactcaaa gcttttagaa tctcttgata atgaccaatg ctatttaaac tgagagcttt
    10681 ttccatgact ttttgaataa cttcacgttg acgtttttga cgaccataat ccccctcagg
    10741 atcttggtaa cgcattcgtg catagactag ggcttcttct cccccaatat gttgctcccc
    10801 aacaccgata gaaatggtat taaattcttc ttggtcactg atagaaattg ggaaacctag
    10861 gatattattg actgtaatac ctcctactgc atccactagt ttttgcaacc ctctcatatt
    10921 gaccatcaca tagcgatcaa tatggatatt catcattttt tgaatggttt ctatagcaag
    10981 ctctgctcca ccatctgcat atgctgagtt cagtttcgct tcatgagcct gaccattccc
    11041 tgattcaatg cgcgtcagaa tatcccgctc taaactcatc attgttgttt ttttcgtttt
    11101 aggattcact gtcatcaaga tcatgctatc acttctaccg acccaagttt cagttcgttc
    11161 aacatttccg gtgtccactc ccattaacag aatggttaga ggttcagtcg cttcaataac
    11221 cttggtttct tcgccgattt ttttataggt tttagctaag gtttctgtcc cttgttgata
    11281 aatagtataa gcaaaaacac ctactcctac tacagttaca gaaagtaaag ctagcaccat
    11341 tccaataatt tttttaacca tatttctact aacctatcag tttacccatc aagtaaacat
    11401 cgataaattt cccttcttct atatatgccc cacgctcttg gctaccttca atgacaaagc
    11461 catgcttttg ataaagatgg actgctgctt gattacgagt ttggacagtc agttggagac
    11521 gacgcagaat gccacttgct tgtgcccact ctatcgcttc ttctagcaac aaacttccca
    11581 agccattatt ccaatatctt tttccaatca caatgaagag atctccaata tgacggactc
    11641 tcttacgctg atcagctgta atatttacaa taccagcaat tttgccattt aagaatgcaa
    11701 gtaaggttat ctgattgtcc gaactagctt gcttgttgag gaatatttcc atctcctcac
    11761 tagtcaagag aataccatct ccgtctaggc tggtaaagtc tgtctccaaa ctcacacgat
    11821 ttaaaaaggc cactaattca gctgcatctt tgggctctgc ttccctaatg agcaattcat
    11881 actccatatt gaagctcctc taacaatttc tcagcacgca aaccctttgc ctgaaaattt
    11941 aaacggcgtc catctgcttc ttttagaatt tccaattcta aataagcatc tggcaaggca
    12001 tctcctaaga gatttcccca ctcaataaca gtcacgccgc caccaaagat aaactcatcc
    12061 aagtcgatag aatcagcatc tccttcaata cgataaacat ctaggtgata aagtggaagt
    12121 cgaccttcat actctctcac gatagtatag gtgggacttt taatcatttg agaaatctgt
    12181 aatccttttg caagtccttt agtaaaggtc gttttacctg cacccagttc tccagttaag
    12241 attaaaacat cattctttgc taatagatgg cccaaacgct cccctaaggc ttgcaactct
    12301 tcttcatttt ttgtgtacat actcttatta taccaaaaac ttttcttttg tgtctatttt
    12361 cctactaaac ttatcatcat aacatccata caaaaacagg ctttctctaa aagaaaatga
    12421 gcgtaacaat gaccaataca agatctcgga aaatatgacc ataaaaggat acttccttct
    12481 taaccgaatt tgggacaaga taggctgcaa aaaacaagcc cagtccaata taaatcagaa
    12541 gtgagacaat ggtcattgga tttcttaaga aaagaagtgt tgctaaaata gtcaccaaca
    12601 ctgtcttttt tctgtctagc atagcaagaa aatcgcgcac gtattttttc aagggtaaaa
    12661 aaatcagcaa atctagccca aataggaaaa agaaggatgg caataaaaag tcaactaatt
    12721 cttgctgcag cgtatttttg atgaacaagt tatctgacaa aacaagaaca gctcctaaca
    12781 aattaattaa gagtaacata ctgtaaaaaa gcttcaccga cttcttactg gctaggacac
    12841 tatggacttc ttgcttacgg gtataaagat aatttactcc agcacagatt cctgaaacga
    12901 aaaccatgct tccgatgaaa aaagctgtac tttgtttaaa ggacaagatg cattccttcc
    12961 ataggaaaca gctactcaaa ctgatttgaa ttaaagctaa caaaaataag attctcattg
    13021 atttcatctt ctctctccct tcctaccaat cattatacta ggagaaaaga gagaactgtt
    13081 tctaatcttc tcaaatgtct ctttaagacg ctaaacaaac actagagact aatactcaat
    13141 gaaaatcaaa gagcaaacta ggtagctagc cacaggttgc tcaaaacact gttttgagat
    13201 tgcagataga gctgacgtgg tttgaagaga ttttcgaaga atataaattt gaaatcatga
    13261 aaatccgtca aacgggtggt tgttttgtct cgcacctcac ggagcgagac ggactcagag
    13321 tcacataatt ataaggctga tagtattaat ctaactatca gccttacagg ctatttaatg
    13381 tttaagtaac actccaatat caagataaac taaacagcat ctagttcctt caaataattt
    13441 tctatcttca tcagcattaa aggattgtta taaatcttgc atagctctct tgcttctata
    13501 taataatttt tgacttgttc tctgtctaga aatttggctc cagcatttcc tacaagaata
    13561 agtagaggag ccaattggta gcttgtctgt ctttgtttac agagttcaat cgtttcaaga
    13621 gcttcttgga tggcttcatt atatttttcc tttgatacta ggtagtgagc gtagttgtaa
    13681 cgaactctga tgtagccaaa taaaaactct tgatggtcca aattttttgt ctgatacaac
    13741 tctattaaat gagagtagtt tgcctcatat tcttgttcac gacccactaa ggaatagaaa
    13801 ttagatagag tattcaacgc ctttaaataa atcagagtat ttgaagagac ttttaataat
    13861 atattttcca atgaagaaat tgcctcacac ttactgtcat attgatataa gtcaataata
    13921 gctttaatcc attcaaggta agttcggtct tctagtgtta gaaaagtact tcgttcaatc
    13981 tctattctat aaatatattc caaatcgtca taatttctat cgtctaatag tcgagcagac
    14041 aattgcttga aattagagag gttagattta atttcaattt gttcattaaa aaaataatct
    14101 aatggtactt caagtcgttg agagagtttg aacaaaaggt ctgcggaggg aatgaaatgc
    14161 cctctctcaa ttttactaat ctggctttgt tcacaaattc cttctgcaag agtttgttgg
    14221 gagagtctca actcttttct tttcaatctg aatttctctg cgagtgtatt cattaaagat
    14281 aataaacctt cctatttgct taattgcatt ataaaatttt tagttcaaaa tagcaagtta
    14341 aaggaataaa taattcttta tggtaataaa ctaaaaaaag tcaaaaatta cataaaaatg
    14401 cttggctaaa taaaatatat ctgttaaaat aaggataatg aaaaagaaaa gggtttcacg
    14461 aatgaagaaa aatcgtggaa ttcaaaaatt agctatatta gtattactag gtgtttttat
    14521 gtttagtaat acaattcctt accaacagtt tattcagaag aatagacaat tggagattcg
    14581 agtgcaatcg caaaagaagt ccaatggtct tgatgttggg aaggctgatt gatttcgtat
    14641 tactttaaaa ttcaactatt tagagaaagg tattctgatg agagcttgta acaataccag
    14701 atagatatta gtaagcttgt tagtttatag agggcagggg tatttctgcc ctctgtttta
    14761 gaataaggaa tgcactatga aaaaattatt tatactcata tccaacctgc ttgctagttt
    14821 gttctttgtt tgggtattta ccatttggac tgatacatat gtctcctatt attaccccaa
    14881 cgttgttgta catgattctt cccctgaaac aacttttcag catgttgcta cacgcttgga
    14941 aaaactagca gaagaaacag atagctttat tgcgattcaa caccaagatt ctaactcaga
    15001 aggtactaca gttttttctt atacgacctt tggggacgga aagttgcctg atgggcttca
    15061 ggaaaaaaat ctagaagatg ctcaaagtag tagtgttgaa acaaactatt ttgtattcga
    15121 tggacaccta gatattcact tgctaaggga agagctaagt caacttggct tgactaacat
    15181 gcacctgaca attccatcta aactatctac gttaatggct atctttagta acggatttca
    15241 gttaatcagt ctattgattt tcatcttaac ctttgtagca ctgactttaa ttagtcaaat
    15301 tagccaatta cggtcatcgg gcattcgcct catttcagga gagaaacggt ggtccatttt
    15361 ccttagacca gttggtgagg atttgaaagc gatagctgtt ggtttcagtt tagctggcgt
    15421 gctcgccatt cttatgcaaa aaattctgtc gcttccaacg caatccctaa tgaccatagg
    15481 agcaggcttg ctcagttata atctcatctt gttgtcgatc tccctgtttt tcgctcaact
    15541 cttcgcagtt gggataaaaa agatacacct gatgcagatt ataaaagggc aagtgcctgt
    15601 cagaggaatc attagtttga ttttaatcgg tcaactgtta gcgattatta ttgtaacgct
    15661 gggaataggg agtagcttaa agtattccca agcctggcaa cagcatcgga ttggacaaga
    15721 ggcttggagt caggaaaggc aactgattac cctatcaatc agccgtgaag gaacgagtcc
    15781 tggttttgat gaacaagctc aaaggaaact cagaacttgg tatcaattga tggatctggc
    15841 tgtttcagaa caaaaggctt tcttatctag acaccagtta attgaccgta ctttgcaaaa
    15901 tggcatggct tcctccaaaa acttgataac ctctacagaa tggcacgatt acaacccaaa
    15961 tggcaatgtc cttatcgtca caccgcaata cttggagcgt caaaacattc ctgtagatac
    16021 aactattgag caaaagatga atcaccttga tgtaggggag tttgtcttat tgctgcctga
    16081 acacctccgt tcagaggaag aacattataa atctgttttt gaagacgact taaccagtcg
    16141 catgtctagt caagatgaac gacagcaaat gactgctacg gtaggttatt tagaatcagg
    16201 tcaggatcgt tttgtgtata atacgacccc tatttcttac cagcagtttt tgaaagatcc
    16261 aatcatcatt gttataacac cccaatcaac tggtccacag tccattttgt tttggataga
    16321 cgcagtacag aactacgttc tctttaatca attgtctgat gcccaggagc ttatccagag
    16381 acaaggcatt gaaaattggg tctcagaaat gcaaacaggt taccacaact acatcacatt
    16441 attggataat atccagaggg aacgttgggt aatgctagca ggagctgtgc ttgggattgc
    16501 aacttcaatc ttgttgttta acactatgaa taggctctac tttgaagaat ttagacgtgc
    16561 catttttatc aaacgcattg caggtctcag gttcttagaa atccatcgca cttatctctt
    16621 tgctcaactg ggtgtgtttt tactgggatt tgttgcgagt gtatttcttc aggtagagat
    16681 aggagttgct ttcttagtct tgttactctt tactggtcta tctcttttac agttacatgt
    16741 ccaaatgcag aaagaaaaca agatgtccat gcttgttttg aagggaggtt aatatgattg
    16801 aacttaaaca ggtgagtaaa tcttttggag aacgagagtt attttcgaat ctttcaatga
    16861 catttgaggc tggaaaagtc tatgccttaa ttggttcaag tggtagcgga aaaacaacct
    16921 tgatgaacat gattgggaaa ttagaacctt atgatgggac gattttttac cgaggtaaag
    16981 acttggccaa ttataaatcg agtgattttt tccgtcacga attgggctac ctcttccaga
    17041 actttggctt aattgaaaac caaagtattg aagaaaacct taagctaggt ctcattggtc
    17101 aaaagttgag tcggtcggaa cagcggttga ggcagaagca ggctttagaa caggtcggcc
    17161 tggcttatct tgacctagat aagcgcatct ttgagttatc gggcggagaa tcgcaacggg
    17221 ttgccttggc aaaaattatc ttaaagaatc caccctttat tctggcagat gagccaacag
    17281 cttcaataga cccagcaacc tctcagttga ttatggagat tttgctatct cttcgagatg
    17341 ataataggct aatcattatc gcaacacata atccggcaat ttgggagatg gctgatgaag
    17401 tgttcacgat ggatcatctg aaataaaaat ccttgttttt aattgcacga tgagttactg
    17461 aaatattatc atgaatcaag aattggagtt aatttagaat tgtactttat taatattgag
    17521 gtaacttttt cttgataaag gaagaaataa tggagaggaa gttagaatga aaaaattcga
    17581 caattatatt attgagaagc cttgcgattc taattcagat aaactgcaaa aaatcttaat
    17641 aattgaaaat ttggtagatg atattttgca atttcctctc agaatcaata atagtgtagg
    17701 agagattttc ctcctacaac cgtttcaaaa gaaaactatc tttattccat gttattttga
    17761 ggaagatatt gtgaaagtca aagatgatga taaagttgag tggaatttgt tagaatttca
    17821 aaaatttaga gcatttttgg cttagtaatc tgtgttgaag gctcaaaacc tatggtaaaa
    17881 aagtcgcttt gaaaacgtat tgcctccaaa gatttagtta aataatgatt taacacaaaa
    17941 agaaattatt gaagttctgg aaagatgttg tttcagtatt gagaaaagat gggaaaaact
    18001 tgcgattttc acagagaaag gaagaaaaag tatagaaata tagtcaattg aaacaagaac
    18061 aggacaaaag aaccttttgt gccatatttt tctcctttcg ctttacaatt ggcttgaaca
    18121 cctttattgt atcgcgtttg gagttttttt ggtataacct tcgacgcgca cccgcatagt
    18181 gggtgttttt ttgtctcgca cctaacggag cgagacaaac taatagtcac ttaatcaaaa
    18241 aacgcaccat atcaaaaact aaaaagtttg atatcatgcg tcatgtctta aactaattga
    18301 ctatactttc tattcaaatg agcttttaac caattgattg agccaatcca ctcttaaaac
    18361 caaagagcaa tttctcgctt agctgactct tctgaatctg aaccatgtac aacattttgg
    18421 ataatctcat tttctccagc agcttttgca aaatcacctc gaatagtgcc tggtaaagct
    18481 tcttctggac gagttgcacc catcatggtc cgccaagttt cgattacttt gggaccagaa
    18541 atgacaccca caagaactgg acctgaagtc atgaattcac gaatcggtgg gtaaaaactc
    18601 tgaccaacca agtcctgata gtgctggtca atcaactctt ctgaaacctg tgaacgaaac
    18661 tccaattttt cgattgtaaa tccacgttgt tcgatgcgct ttaacacttc acccactagc
    18721 cctcttttta caccatctgg tttgatgata aagaatgttt gttccatacc cgtctccttt
    18781 gtcagcttct ttcttttatt ttaccacatt tcgtggaaaa atggagaaag ttttcagaag
    18841 agagaatgag agaaccctcg ggttctctca ttctctctta ttctactgtt tcttccacag
    18901 tttcaacggc agtatccaca actacttctg ttgtttcttc atttccttct tcctctactg
    18961 gaggattaag gtattcttct tcgttgacag catatggttc aaggttacgg taacgggcca
    19021 taccagtacc agctgggatg atcttaccga tgataacatt ttctttaagt ccaaggagat
    19081 ggtctttctt accacggata gctgcgtcag taaggacacg agttgtttcc tggaaggaag
    19141 ccgctgacaa gaaactgttt gtttcaagtg aggctttggt aattcccata aggactgggc
    19201 gacctgtcgc tggaactcca cctgcgataa ggacatcttt gttggcatct gtaaagtcat
    19261 tgatatccat gagggtaccc atgagaagat ctgtatcacc tggatccatg acacggactt
    19321 tacggatcat ttgacgaacc attacctcga tgtgtttgtc accgatttct accccttggc
    19381 tacggtaaac tttttgtact tcaccgagaa ggtacgtttc aactgacaag acatcacgaa
    19441 ctgcaaggag acgttttggt tggatagaac cttctgtcag agcagcacca cgcgctactt
    19501 ggcccccaac ttcgacacgc atacgagctg taaatggaac gacatattca ccttcgccag
    19561 tttcaccctt aacaaagact ttcttggtac gagttgatgc atcttcttcg atagcagtaa
    19621 cttgtccttt aacctctgta ataaccgctt cccctttagg attgcgggct tcaaagattt
    19681 cttggacacg aggaagaccc tgagtgatat cggtatttga ggcaacccca cctgtgtgga
    19741 aggtacgcat tgtaagctgt gtaccaggtt ccccgataga ttgggcagcg attgtaccaa
    19801 ctgcttcacc aacttcaacc gcatcaccag tcgccaagtt gataccgtaa cagtgacggc
    19861 agacaccgtg acgagtgtta catgtaaata cagaacggat agtcacttct tccacaccag
    19921 cattgacaat ttcacgcgcc ttgtcttctg taatcaattc atttggacca ataatcactg
    19981 caccagtttc tggatgttta acagttttct tagtgtaacg accgttgaga cgctcttcga
    20041 gagactctat catctctttt ccttctgcga tagaacggat caagagacca cggtcagttc
    20101 cacagtcgtc ctcacggatg ataacgtctt gggcaacgtc gaccaaacga cgagtcaagt
    20161 aacctgagtc ggctgtctta agggccgtat cggtcatacc tttacgagca ccgtgagttg
    20221 agaagaacat ttccaatacc gacaaacctt cgcggaagtt tgaaaggatt ggcaattcca
    20281 tgatacgtcc attcggagca gccatcagac cacgcatacc ggcaagctgt gagaagtttg
    20341 agatgttacc acgggctcca gagtccatca tcataacgat tgggttctta ggatcttgat
    20401 tagcaatcaa gcgtttctca agtttttcac gggcagcacg ccattcagct gtaacagcat
    20461 tgtaacgctc gtcgtctgtg atcataccac gacggaattg tttggtgatt tgttcgacac
    20521 gtttgtgtga ttcttcaatg atttcagcct tgtcatcaac gactgggata tcggcaatac
    20581 ccactgtcaa tcctgcaaga gttgagtggt ggtaaccgag gttcttcatg cggtcaagta
    20641 gggcagaagt ttctgtcgta cggaaacgtt tgaagatttc agcgatgata tttccgaggt
    20701 ttttcttctt gaatggaggg ttgagctcaa gattgctgat agcttccttg atatctccac
    20761 caagtggcaa gaagtattta gctggaacac cttctgtcaa gttggcattg tttggttctt
    20821 gcaagtatgg tagcccctct ggcatgatat cgttgaagag aattttacca actgttgtaa
    20881 gcaagacctt atgtctttgc tcttctgtcc aaggcttgtt gaggctgtct gttgcgatac
    20941 caacacgtga gtggaggtga acataaccat tgcggtaagc cataaccgct tcgtcacggt
    21001 ctttgaagac cattccttca ccttcgcgac cagcttcttc catggtcaag tagtagttac
    21061 ccaaaaccat gtcctgagat ggagtaacta ccggtttccc atctttcggg ttcaagatgt
    21121 gctcagcagc tagcatgagg atacgagctt ctgcttgtgc ttcttctgaa agtggtacgt
    21181 ggatggccat ttggtccccg tcaaagtcag cattgtaggc ttcacagaca agtgggtgca
    21241 agcgaagagc cttaccatca atcaagactg gctcgaaggc ttggataccc aaacggtgaa
    21301 gggtcggtgc gcggttcaaa agcactgggt gttctttaat cacttcttca aggatatccc
    21361 agatacgctc atctccgcgt tccaccaagc gtttagctgc tttgacgttt tgcacgatat
    21421 cacgggcaac gatttcacgc atgacaaatg gtttaaagag ttcaatcgcc atttcacgtg
    21481 gcacaccaca ttggtacatc ttaagagttg gaccaacggc gataacggaa cgtcctgaga
    21541 agtcaacacg tttaccgagc aagttttgac ggaagcgtcc ttgtttacct ttaagcatgt
    21601 ggctcaatga tttcaatgga cggctacctg gtcctgtgat tggacgacca cgacgaccat
    21661 tgtcaatcaa agcgtcaact gcttcttgaa gcatacgctt ctcattttga acgatgatac
    21721 ctggtgcatt taactcaagc aaacgagcca aacggttgtt acggttgata acacggcggt
    21781 aaaggtcatt caagtcagat gaggcaaaac ggccaccatc caactgcaac attggacgaa
    21841 gatctggtgg gataaccgga aggatgttaa gaatcatcca ttcaggtttg tttccagact
    21901 tgtaaaaggc atccaaaaca tccaaacgac ggatggcttt gacacgtttt tgtccagtag
    21961 ctgttttcaa ttcttctttg agttcagcaa tttctttttc aagatctact tgcttcaaaa
    22021 ggtcttggat ggcttccgca cccatcttgg caacaaatga accataacca tattcacgca
    22081 agcgctctcg gtattcgcgc tctgtcatga tagacttgtg ctcaagtggt gtatccttag
    22141 gatcaattac cacataagcc gcaaagtaga taacttcctc gagggcacga gggctcatat
    22201 caagggtcaa gcccatacgg cttggaatcc ccttgaagta ccagatgtga gatacaggag
    22261 ctttcaattc gatatgtccc atacgctcac gacgaacttt cgtacgcgtt acttcaaccc
    22321 cacagcggtc acaaacaatt cctctgtaac gaatgcgttt gtacttacca caagcacatt
    22381 cccagtcttt tgtaggacca aagatcactt catcaaagag tccttcacgt tctggtttca
    22441 aggtacggta attgattgtt tcaggttttt tgacttctcc ataagaccat gaacggactt
    22501 tacttggaga agctagggtg atttgcatac ttttaaaacg atttacatca accactattt
    22561 cttccctttc tattctaagt gaactgctta ttcctgttca gcagcttctt ctgttgcttc
    22621 cgcttttgtt gctttctcag cttcttcagc ttcaaaggct gctttagcct cttgggctgc
    22681 tttttcgcgg gctttttcaa ggtcatctac gtggatgaca tcttcgtcca ttccttcatc
    22741 caagtcgcga agttccactt cttggtcatc ttcgtctagg acacgcatgt caagaccaag
    22801 agattgcaat tctttgacaa gaactcggaa ggattctgga acacctggtt ttggaattgg
    22861 tttgcctttt gtaatagctt cataggcttt caaacgtccg ttgatatcgt ccgacttgta
    22921 agtcaagatt tcttgaagga catttgacgc accgtaggct tcaagagccc aaacctccat
    22981 ctcaccgaaa cgttgtccac caaactgagc tttacctccg agtggttgtt gggtaacagt
    23041 tgagtaaggt ccgactgaac gcgcgtgcaa tttatcgtca accatgtggt ggagtttgat
    23101 catgtacatg actccaacag aaacacggtt atcaaatggt tcacctgtac gtccatcgta
    23161 aaggattgtc ttggcatcgc tatccatacc tgcttcttta acagttgacc aaagatcttc
    23221 agaacttgct ccatcaaaga ctggtgtcgc aatgtgaata ccaagagtac gagctgccat
    23281 accaaggtga agctccataa cctgaccgat attcatacgt gatggcaccc caagtgggtt
    23341 caacatgatg tcgactggag ttccgtctgg aaggtaaggc atgtcttcta caggaacgat
    23401 acgagagaca acccctttgt ttccgtgacg tccggccatt ttatctccga ccttaatctt
    23461 acgtttttga gcgatgtaaa cacgaaccaa catgttaaca cctgattgca actcatctcc
    23521 atttacacgt gtaaagatct taacatcacg aacgacacca tcggcaccgt gtggtacacg
    23581 aagagaagta tcacgcactt cacgagactt gtctccaaag atagcgtgca agagacgttc
    23641 ttcagctgaa agatctttct cacccttagg tgttacttta cctacaagaa tatcaccttc
    23701 tttaacctca gcaccaatac ggataatccc catttcgtca aggtctttga gggcatcttc
    23761 accaacgttt ggaatttcgc gagtgatttc ttcaggccca agctttgtat cgcgcgtttc
    23821 tgattcgtat tcttcaaggt gaacagatgt gtagacatcg tccttcacca agcgttcgct
    23881 catgataacg gcatcctcga agttgtaacc ttcccaagtc atgtaggcaa cgattgggtt
    23941 ttgtccaagc gccatttctc cattttccat agaaggtccg tcagcgatga aatcgccttt
    24001 ttcaacgaca tcaccaactt ttacgagagt gcgttggttg taagcagtac ctgagtttga
    24061 acgacggaat ttttggatgt ggtaaacatc caatgaacca tcttcacgac gaacttctac
    24121 cttgtcagca tctgcgtaag taactttacc atcatactga gcaatcacag ccgcaccaga
    24181 atcgtgggct gcttggtatt ccataccagt accaacgtaa ggtgcctgag gattaatcaa
    24241 tggcacagcc tgacgttgca tattggctcc catgagggca cggttggagt catcgttttc
    24301 caagaaagga atacatgctg tcgcaacggc aactacctgt tttggtgaaa cgtccatgta
    24361 gtcaacaata ttagctggat actcttggtt gaccccttgg tgacgtccca tgacaatctt
    24421 ctcagcaaag gttccatctt cattcagacg agagttagcc tgagctacag tatattcatc
    24481 ttcttcatca gctgtcaacc aaacaatttc gttcgtgaca acacctgttt cacggtcaac
    24541 cttacggtat ggtgtttgaa caaaaccata tttgttcaag tgtccgtaag atgacaagtt
    24601 attgatcaaa ccgatgttag gtccttcagg tgtctcgatt ggacacatac gaccatagtg
    24661 agtgtagtgc acgtcacgta cttcatatcc agcacggtca cgagtcaaac caccaggtcc
    24721 taaggctgac aaacggcgtt tgtgagacaa ctcagaaagc gggttgtgtt ggtccatgaa
    24781 ctgtgacaac tgtgatgaac caaagaattc tttaactgca gctgttacag gacggatatt
    24841 gataatttgt tgtggtgtca agacttcatt gtcctgaaca gacatacgtt cacggacatt
    24901 acgttccata cgagaaagtc ccaaacgtac ttggttggca agcaattcac caaccgcacg
    24961 gatacgacga tttccaaggt ggtcgatatc atctacacgg ccaagtcctt cagccaagtt
    25021 gaggaagtag ctcatctcag caaggatatc tgcaggagtc accgtacgaa ccttgtcatc
    25081 tgggttagca ttaccaatga tcgttacgac gcgatctgga tcagttggag caacaacctt
    25141 gaatttttga agaacaacag gctcagtcac aacggctgca tcgtttggga tgtagacaat
    25201 cttgttcaag tcgccatcca aatggctttc aatgctttca atcacgctac gagtcataat
    25261 cgtaccagct tctaccaaga tttctccagt ttcagggtct accaatggct ctgcaatggt
    25321 ttggttgagc aaacgtgttt taacattgag ttttttattg attttgtaac gaccaactgc
    25381 tgccaagtca tagcgacgtg ggtcaaagaa gcgagccaca agcaagctac gtgagctttc
    25441 agctgtctta ggctcacctg gacgaaggcg ttcgtaaatt tctttcaagg cttcgtctgt
    25501 acgagagtcc attggattct tgtggatatc tttttcaaca gtgttgcgaa ccaattcgct
    25561 gtcaccaaag atatcaaaga tttcatcatc acctgagaaa ccaagagcac gaaccaaggt
    25621 tgtaaatgga atcttacgag tacggtcgat acgagtgtag gtgatatctt ttgagtcgct
    25681 ttcaagttcc aaccaagctc cacggttagg gataacagtt gaaccatagc ccaccttacc
    25741 atttttgtct actttgtcgt taaagtaaac acctggtgag cggaccaact gagaaacgat
    25801 aatacgttca ccaccattga tgatgaaagt acccatttct gtcatgattg ggaaatcacc
    25861 aaagaaaact tctttggtct tgatttcgcc tgtttcttta ttgatcaaac ggaaggttac
    25921 aaaaattggt gctgagtagc tagcatcgtg gatacgagct tcttctagcg tgtattttgg
    25981 ttccttgatt tcatatccaa caaattccaa ctccattgtg tctgtgaagt ttgaaattgg
    26041 caatacatct tcaaacactt ccttaagacc gtggtctagg aaagctttga atgagtcagt
    26101 ttgaatttca atcaaatttg gtaagtcaag aacttctttg attcttgaaa aactacgacg
    26161 ggtacgatgt ttcccgtatt gaacgtcatg tcctgccaag atgattctcc tttgtaaata
    26221 agttccaagc cttgtcaatc aggcttttct aatcgccata tggttgtaaa ccccttatca
    26281 ccgtgtcctc ttgacgaatt ttcagaatct ttaagcctct gttacaaatg ctcaaaatct
    26341 tgaaaaaaag cacaaaaaga gcagctaaat ctgacttttt cagaagattt aactgctgtg
    26401 agccttgtct ggacaatatt tcagacaaaa cctacgacaa atgattaccc atattatacc
    26461 ctatttagct agatttttca aggggtttca gtaggttttt ggtaaatttt ttcccataga
    26521 aaacttggca tcacattcga atcacgctat ggtacaaaaa actgaaaaaa ctattgactg
    26581 aaaatcattt tcaaggtata ataataaacg ttaaggcggt atagccaagt ggtaaggcac
    26641 ggctctgcaa aagcttgatc gtcggttcaa atccgtctac cgccttctat aacttgattt
    26701 atcaggtttc aaatgaacag aaagcccaat ttgaagggct ttttttattt tccctcgaat
    26761 aaatacgtat aactttaaaa acttttggag cgagtttgtg gcagagttct ttccatggca
    26821 taattccctt ttgaaatcaa ttgaaaaaag cttcgtcacg cctggtgaca aaagcctcta
    26881 gtttattctg tttcttcttc tatttcgact tctgtgattt ggacttttac cttggtaaca
    26941 cgtccattct tcactttatc attggttaag ataaactgtt tgttttggct aaccaattca
    27001 tagctgagtt tctcagtcgt tggaatagtt cccactcctg tcaaataata accagcgatg
    27061 gtatcaacgt catcactttc cagttcaaca tcaaagtaat tattgaaatc attgagggtc
    27121 atagttcctt gaacaatgta ggtatcctcg ccaatctgat gaacatctat tgctgctttg
    27181 tccgtttcat catcaatttc accaacaatt tcctctaaga ggtcttccaa agtcaccaaa
    27241 ccagccatac caccgtattc atccagcaag attgccattt gtctttgggt atttcgcagt
    27301 tcttttagca agtcatccac aaaaatagtt tcaggtacaa aaagtggatc ttgcaaaatt
    27361 ctcttccaaa caatattgtc aaaaccgtcc acaaagcctg ccttaaggag actcttggtg
    27421 tgaatgattc caattacatt gtccttatcc ccatcataaa ccgggatacg agaataattt
    27481 tgttttaaaa tactttggat aatggcttga ctatcatcct gaatatccac cataaaggca
    27541 tccgttcgag gaaccataac ctctcgtgcc atcagttcat cgagcgaaaa gacaccttgt
    27601 agcatctcaa tctcatcagc atccaatgtt tcttcactat ttgtcagcat ataggcaatt
    27661 tcatcacggg tcatcttttc atccgcatca tcgaatgaca taggagtcaa atggctcaag
    27721 aaattggtcg aagcagctaa aagccaaaca aaaggactga ctagttttcc gatcccaatg
    27781 ataaccggcg ctgtacgaat tgccaaggca tcctttagat taagagcgat tctcttagga
    27841 tataattccc caaaaacgat ggaaatatag gtcaaaaatg ccaaggatag aaaagttgcc
    27901 acggcttgtg ctgtttcgcc attcccaagc caagaggcaa tcacacgtcc tagagtatta
    27961 gttaaactcg cccctgataa gattgtaatc agggtgattc ctacctgaat ggttgataaa
    28021 aagtggttag gattttctag taccttcagc aggcggatgt agcgtctgtc tccttcttcc
    28081 gccttttgtt caactcgggc acgattaaga gaaaccatgg ccatttctgt ggctgagaaa
    28141 aaggcattta ataccgtcaa gataaacaat aaaacaaatt gtagcaacaa attctgacta
    28201 cttgggtctt ccatagttct tctcctaaaa tagtatctta tcctttatta tatcacaaaa
    28261 tttaatccaa tacatattat tttttcttac cgtaacttct caaagtaact tccatctctc
    28321 tcccaaaact ggaagttagt tttagaagtt gctatttttt cttagtacct gttctagccc
    28381 tgcttaaact agtaaaaaga actcctacat ccataagtga cataggagtt taggcttatc
    28441 ttttactgag ttacagttac ttctccagtt cggtaatcca gttgaagtcc cttttgaaca
    28501 ttgggaacta gaacattgaa ttccaattct ccatccgaag acttggcttc aatctgtgaa
    28561 gctgagggaa ctaaatcctc gtttgaagcg tagtaaaggg ttacacggta acggacacgc
    28621 ttgttttggt ccaaggcttt acgcaccttg ctttcatagt agttttgacc agtcgaatac
    28681 tcggcttgtg cctgatttgc ccaggctgtc tgaacagcaa tgtttttagg attgcttgtt
    28741 gaggcatcaa aaccatccaa accaccgatt aaggcatagc ctaacaaatg acctctatcg
    28801 actgcatggg tataagagcc ctttagattc ttgacctgat gccaacctgg aggagtccaa
    28861 gaagttgaac cattcccagt ttctttacga ttcttgtact gacgagtggc cttagacaag
    28921 agggcattag ctacggttgg aacagtttcc ttgcccactg tctttgtttt attgtcagcg
    28981 tagggcttac ttgaaacctt ggcatctaga tttgttttat taccattgac gataaaagca
    29041 cctgagccat tccactccag actccccttt atttgactct tgactgcgtc tgttaagaca
    29101 ctctctgcca atgcttgact aggagcttca gacgcttgtt ttttctgact aagattggtt
    29161 ttgggactat taggtgccga cggcatctgc ttgatataat agctccctgt agacaaaagc
    29221 aataacacta gcagtccgat tagtgtctgt cttgtttttt tgttcatatt tctccttatc
    29281 tttagaaaaa ggctggttct ccagcctaat ttcctgtaaa tttatgaatc aattcctgcc
    29341 attttgctgg agacaggata gcccatggat cttgaccctt gcccaagatt ccataaccta
    29401 ccattagacc gattcctaga gccagagtac ctaaaatcag tactatgatg actaaaagta
    29461 aacgattgat tacgtagctt gatttcttat tcatcttcat cgcttgcctc aatccgctga
    29521 atcttagcac ctagctgcgc caacttctca tggaaaccgt agtaacctct atccaagtga
    29581 accaatttac cgaccacagt ttctccctgt gctaccaaac ctgtcaaaat caaggctgca
    29641 ctggcacgaa ggtcagttga aagaacttct gctccctgca aaggctgtcc accaacaata
    29701 cgagctgtat cacggataat ctcagaatgc aagcccatgc ggcgcatctc ttctaggtgt
    29761 tggaaacgat tttcgaaaac tgtctccacc atggttgatt cgccttttgc aactgtcatc
    29821 aaggctgtaa attgagcctg catatctgtt ggaaatcctg ggtggggcaa ggttttcaca
    29881 tgaacagctt ttagattttc cagttgagaa cgaacacgaa ttccttcgtc ttcttcaatt
    29941 acttcaacac ccatttcaag taacttggca atcaagggac ggttgtgctc ccagacagcg
    30001 tctcgaatca agacatcacc accagtcatg gcagcagcta ccataaaggt tcctgcttcg
    30061 atacggtcct ggactacatt gtgagtcgta ccatgaagtt tctcaacacc agtaatggtt
    30121 atagtctctg taccagcacc tttgaccttg gctcccattt cattaaggag aatggctaag
    30181 tcaacaatct caggctcacg cgcagcattc tcaatcactg tcaccccatc agccagagtc
    30241 gctgccatca tcaagttctg cgttgcacca acacttggaa agtccatata gatatgagca
    30301 ccatgcaagc gttctgcctt ggcttcgatg taaccagctg tctgactaat cttaaccccc
    30361 atagcttcca gacctttcaa atgaagatca ataggacggc taccaatcgt acaaccacct
    30421 ggcatggata ccttggcatg acccacacgg gcaaggattg gccctaatac aacgatggag
    30481 gcgcgcatct tactgacata cttgtaaggg gcttcctcag tgatgtcgcc agtagcatcc
    30541 accttgacaa gatgagcttc ctcatcaaag tcaaccttgg cattcaaacc accaactacc
    30601 tgattcataa taaagacatc cgacaaaatc ggaacattct gcaagacggt ctttccttca
    30661 cttgctagaa tagtcgctgc caacaagggt aagactgcat tttttgctcc ctcgatcgtc
    30721 acgcttccta ccagacgatt atcgccacct tgaaccacaa ttttatccat actcgtttcc
    30781 tttactcttg attttataat aatcctctaa gcgcttcttg ccacaaatga tacaggctaa
    30841 taaagaaaga actcaggatg tagcctatga caatgctaaa aaaggctact aataaacgaa
    30901 cttttcttgt attatcatct gtcactttta aaaccttctc ccatctaaca agatccttta
    30961 aaaggtaaaa actcacataa ataaagagca tatgactact tagagtgaat aataattgaa
    31021 ccatttgact attataccat cttctctgtt tgtgcgctag tttggaaact tcactcaaaa
    31081 attagggatt gtttttcaag taatcaatcg catcttgtag ggttttaacg ggcacgattt
    31141 tcatatccgt cttgattgtt ttagccgctt ctagggctgt ttggtagttg tttttcgcgt
    31201 ccggatgcgc cttttgttct tcttcgctaa cagggttatc aggagtaaag aaaatagcag
    31261 cacctgccct agccgaagct acaaccttct tatcaatacc tccaatgtct cccacattac
    31321 catcgcggtc aatggtacct gtaccggcaa caatacgacc attacgaaga tctgggtgag
    31381 ctatttgagt atagatagct agactaaaca tgagaccagc acttgggccg ccaataccag
    31441 ctgttgaaaa gctaattggg acattgctga ttacctctgt acggtcaatc aagccgattc
    31501 caattccatt tttgccattt tccaaggtga taatctttcc ttctgcagac ttggtttgcc
    31561 catcctcttc ataggtgacc ttgacggaat cccctaattt ttgagaactg acgtaatcaa
    31621 tcaagtcttt ggaactatca aaggtctgat cattgactgc tgtgactgta tcagagatat
    31681 tgagaatccc tttaaaggtt gaattatccg tcacattcaa aacataaact ccaaagtact
    31741 tgagttcgat atccttacca gctgttttta gtccttgata cttggccata ttttgcgatg
    31801 tttgcatgta gaattgattg attcgcagaa attcaacatc ggaagaacca cctgtagtct
    31861 cctgagcact acgaatatct gtaaaaggtg tcaaccaagc ataaatcata tgagctaaag
    31921 tggcatgttg aacaccaacc gtaacgaatt gataggcacc agcttcctta tcttctgtgt
    31981 catttacttt aaggacttgg cgaatatctt ccgaaccacc tggaacctct atataataag
    32041 gcaagggcac tacaaatgcc aagaaagtca caatcaaggc cgcaatgacg tataagggcc
    32101 atctaatctt ttttttcatt tcttatttcc tccaaaatac tctcgggaac atagcaggca
    32161 atatcctgac caaacttcaa aagctctcta acgcctgatg aactgatata gagatgttca
    32221 ggtcgactat gtaaataaat agtctctata tcagaagaca gctgatgatt gtagtaatca
    32281 aaactggctt catattgcaa atccgacgca ttcctcaagc ctcgcactag gcaagtagcc
    32341 cccagtcttt ttgcgacatc gaccaccaat ttatcatgag aagacacgac tttaacattt
    32401 cccaaatgtt tcacagcctt ttctaacccc cgtttacgat tttcaagagg gagaaatcct
    32461 tgtttgtggg gattaaaaaa aatacccaca taaagcttat caaagagtct gctcgcccgt
    32521 tcaatgatat ccagatgccc atttgtcatc ggatcaaatg agcctgtgaa taagccaatc
    32581 ttatctgaca tagactgtta ccttactaat tccataaatc ttttccttcc agatacccag
    32641 acaggcaatt tcttctggaa gttcaacggc cttatccgtc tcgcacacaa ccataacatc
    32701 ttcagaaaaa agctctctct cagccatttt ttcaatatct gctacgattt gttccttggc
    32761 atagggaggg tctaagaaaa tgaggtcaaa ttccccagat acctgttcca atgccctttc
    32821 tgcatccatc ttgaggagtt gaaattttcc aacttccttg gtcatctgga tattttcagc
    32881 cacgatggtc tgagccttac ggtctcgctc caccaaaaca gcactggaca tgccacgcga
    32941 tactgcttcg atagataaac caccactacc tgcataaagg tccaagactc gtcccccttc
    33001 aaagtaggga ccaatcatgt taaaaatggc tcccctaacc ttatccgaag taggtcttgt
    33061 tgtcttgcct tctagtgtct taaggggacg tcccccatag attcctgata tgattttcat
    33121 actgtttatt ataccaaatt atagacaaaa agagaaagaa aaccgaacct tgcggttcga
    33181 ttctctacaa aatattttcg taagtatcgc ggacttcttg aggccaaaca cttgtttgca
    33241 cttctccgat gtgtctcttg cgaagtagga acatggccat acgagattgt ccaattcctc
    33301 caccgattgt caatgggaat aggccattca acaaagactt gtgccattcc aattccaagc
    33361 ggtcttcatc acctgtaatt tccacctgac gtctaagagt ttcttcatct acacgaattc
    33421 ccatagaaga caactcaaag gctccaccta aagactcatt ccagacaaga atatcaccat
    33481 ttagaccctt gtagccattc tcagactcgc ttgtccagtc atcatagtct ggtgcacgtc
    33541 catcgtgcgg tttaccatct ggcaactcgc caccgatacc aatcaaaaag acggctccaa
    33601 attctttaca aatcgcattt tcacgttctt tcggtgtcaa gtctgggtag cgttctacca
    33661 attcttctgt atggataaag gtgatttgtt ttggcaagat agactcgatg tcatagcggg
    33721 cttcaacagc tagctcagtc aggcgaatag ccttataaat cttctcaact gtttctttta
    33781 gataaacgat gttacgctta ccatttggaa taaccttctc ccagtcccac tggtcaacat
    33841 aaacagagtg ggttgcatcc aaggaatcct catctggacg aagggctttc atgtggacaa
    33901 agagaccctc tccttcacca aagccaaaac gagccaaggt gtggcgtttc catttagcaa
    33961 gtgagtgcac cacttcataa gtagcatcag ggatttggag aaccttgacc gatactggat
    34021 tttccacacc agacaggttg tcctgcattc cgtcaccgac cttactcaag ataggacctt
    34081 gaacttcgac aacttctagc ttatctttca aatactgggt aaaagtgttt ttgacaaagg
    34141 aaatttcttc ttgttgatgg ataaaacttt tcttcataga caactcctca aaaatttaat
    34201 aaacgtatta tacacctatt tccaagaaaa gaaaagagaa aatttaaaaa aaatcagtgt
    34261 cactcaaaac actgatttca tagacctttt agtcattgcg accaaagata cgtagaatac
    34321 ttaggaaaag attgataaaa tcaagataga tgctgagagc cattgacacc acccagcctg
    34381 tcgctacacg accttgtgat tgttcatagg cgaggcgaat cttttggtta tcccaagcaa
    34441 tcaaccctga aaaaaccaaa accatggcta cgctaatcat ataatcaaag aagccactag
    34501 ccaagaaaat attgactacc atagcaatca gtaaaccaat gagagctgcc atcattgctc
    34561 gaccaatccc actcaagtct ttcttggtaa aaataccaac tgccgccatg acaaagaaga
    34621 gaagggcgct cgatacaaag gcagataaaa ctgtacccgg agtatagaaa gccaccacaa
    34681 aactaagggt aaagccgttt aaaacggagt aaagtaaaaa tactggaaga gcagctggac
    34741 tatttcttga agccatgcta ctggcaacga aaaccaaagc caactccgca aaagtagcaa
    34801 tggtcaacca gagacgcccc tgcatcaaca agtaaaccaa ctgagactga aagaccgtca
    34861 acataaggcc tgataccaaa gcagatagtc cgattcccag accaacaaag gcataaacct
    34921 tagcgtaaaa ttgattgaga cctgcacggt catgtataat agtgtgattc atccttttct
    34981 ccttttctgt gaacatcttt ccttgattat aacaaaaaaa gttaaaatta gcttaaatgg
    35041 aagattaaaa taccggctgc aactgcaaca ttcaaactct cggcctgccc cttcatgcta
    35101 atatggacca actggtctgc actttcagcc ataaggggac taattccttg accctcattt
    35161 cccataacta gtacaaaatt ttctatagaa ggcagttctc tgtaatcaac agaatcttta
    35221 gatagggttg ttgctagcac tgggatagct acctttttag tttcgtcaag aagcgcttga
    35281 ctagtcatcc ggtaaatggg cagatggaaa tgactacctt gcatggaacg tagggttttg
    35341 agactgtaga tgtctgccga cttatctgaa acaatcactc ctgtaaaacc tgctgcatcc
    35401 gcagttcgaa tgatagttcc tacattacca ggatcttgca catcttccaa aaacaagaac
    35461 ttgccctgac tcaaatcagc ttgtcctact tcttcttttt gaaccacggc aacaattccc
    35521 tgtggagtct gagaatccgc caaatctagc aaaatatcct ctgaaatcca gacagtttgc
    35581 ggaaaagcag ctaactgatt tcgataattt tctagggcaa agattttctc aatcgtcact
    35641 ccagcttgga cagcttcttc aaacaagtgc cagccttcaa tcaaataggc agacttgcgg
    35701 tatttttttt ggtgtaattt cttagcattt tttaccacag aattggcttt tgaggttata
    35761 atagtcatag aaatattata acacaatcaa aggggtttgg tatgcaaaag gttagaatga
    35821 ttgcccaagg tagggtgcag ggagtcggct ttcgttgggg tgtttatagc ctggcccttg
    35881 aaatcggtgg catcacaggt cgggtatgga ataacgacga tggcacagtg gaaatcttag
    35941 cccaagcaga ctcatctgct atcatggcaa aatttatcca agaaatccga aaaggaccga
    36001 cacctttttc aaaagtaagc tacttagatg tcaaactaag caactttcct ccctactctg
    36061 attttaaaat cgcaaattag gtctccagaa ctattgtata ttttgtaaaa aaacagtaga
    36121 atagaaaggt ataattttta aagaaggaat aaaaacagtg aaatctatta aacgttttgc
    36181 actctcagct atgggagtgg ctatgttgct tgtcttgact ggctgtgtca atgtcgataa
    36241 aaccacaggt cagccaacag gatttatttg gaatacgatc ggagcgccta tggctgaagc
    36301 catcaagtac ttcgctactg ataaaggtct aggctttggt gtcgctatca ttatcgtaac
    36361 cattatcgta cgcttgatta tcttaccact tggtatctac caatcatgga aggcaacgct
    36421 tcactctgaa aagatgaacg ctctcaagca tgtccttgag ccacaccaaa cacgtctcaa
    36481 agaagcaact actcaagaag aaaaactcga agcccaacaa gccctctttg ccgctcaaaa
    36541 agagcacggc atcagcatgt ttggtggtgt aggatgtttc cctatcctcc ttcaaatgcc
    36601 tttcttctct gctatctact ttgctgccca acatactgaa ggggttgctc aagcaagcta
    36661 cctaggcatt cctctaggtt ctccaagtat gattttggtt gcctgtgctg gtgtccttta
    36721 ctatcttcaa tcgctccttt cacttcacgg agtagaagat gaaatgcaaa gagaacaaat
    36781 caagaaaatg atttacatga gcccactcat gatcgtcgtc ttctccctct tctcaccagc
    36841 tagtgtcaca ctttactggg ttgtcggtgg tttcatgatg attctccaac agtttatcgt
    36901 caactatatc gttcgtccaa aacttcgcaa aaaagtccgt gaagaactag ccaagaaccc
    36961 accaaaagca agtgctttct ctaaaccaag tggacgaaaa gacgttaccc ctgaacaacc
    37021 aactgctatc acaagcaaga aaaaacacaa aaatcgcaac gctggaaaac aacgttcgag
    37081 ataagaagaa aaaggcttag ctgatttgct aagtcttttt gcaaatcaaa agcccgatgt
    37141 ttccatcagg tttcttttct atccatgtac acgtttcata taatcttgat aactttcggt
    37201 atccatgagt tttttagcgt tcttgacgcg atctgctgtt ggtggtttga ctccttcgag
    37261 ggaatatgga attccaagtt cacgccactt gaactcaccc atggtgtgat aaggtagaat
    37321 ttcaaactta tcaacatttt tgagggtctt gacgaactta ccaagttcaa tcaagtcatc
    37381 atctctgtct gtcaatcctg gaactagcac gtggcgaatc cagacaggtt ttccaatatc
    37441 tgatagatac tgggcacaag ccaagatatt tttattagtt tggctagtga caatcttgtg
    37501 ctgttcttcg ttgatttcct tgatatccaa aagaaccaag tcagtgacag ccatgagttt
    37561 gtcaaacttc tcaaggtaac gtggtttatt acggaaagga agagcacagg tatccaaggt
    37621 acagtggatt ccttgttcct tagccttggt gaagagagca atcaggaaat caatctgcaa
    37681 gagagcttct cctccactga ctgtaatccc acccttattt ccccagaaac cacggtagcg
    37741 caaggcctct gtcaagacat catctaccgt ccgttcacgt gacttattgg actccatagc
    37801 ccaagtgtct gggttgtggc aatactggca acgcatgtga cagccctgca aaaagacaat
    37861 aaagcgaata ccaggcccat ctactgaccc aaagctttct gtcgaatgca ccattcctgt
    37921 cacttgtcca taatcaattg tttcttcaga catatcgtta ccttccttga aaacgtttta
    37981 tagttttatt atatcacgac ttgaaggaaa aacaagattt ttgcctattt tttagaaagc
    38041 aatctgtttt tcaatttcat tttcaatcta ttatcagatt attcttcaaa atcgaagcca
    38101 tataaggttg caaaatagtc ctcagggcgc tctgcacggc ggatttgacg ggctttacct
    38161 tcttcggtat agaggatttc cgcagaacgt aatttggcat tatactggta gcccattgaa
    38221 aatccgtggg cacctgtatc atgaatgacc agcaaatcac cgatttctgt atgaggcagt
    38281 tcgcgattga ctgcaaattt atcattgttt tcacagagtg aaccaaccac atctaccgct
    38341 tcagctggtc catctggatg ggtcacgttg ctaatatgat ggtaagctcc gtacatagct
    38401 ggacgcatga ggttgactgc tgaggcatcc acacctagat aggtacggta ggtttccttc
    38461 ttatgagtca ctcttgtgac tagagcaccg tgaggtgcca gcataaaacg acccaattcg
    38521 gtgaaaatct tgacctgacc aagacctgct gacgtaagaa cttcttcata caccttacga
    38581 actccctcac caatcaaggc gatatcgttc ggctcctggt ctggacgata attaacacca
    38641 ataccgccag aaagattgat aaagtctagc caaatgccca acttttcctt gatttcaaca
    38701 gccagttcaa agagctgacg agccaactct ggataataga gatgggtcac ggtattggac
    38761 gctaggaagg agtgaatccc aaaagtcttg gctccttttt ccttcaagat agcaaaggct
    38821 tcaaagagct ggtccttggt catgccaaac ttagcctccc caggattgtc cataatgtct
    38881 gtccccagtt caaaaacgcc tccaggatta taacgacaag agatgatttc tggaatgcct
    38941 gctactctct ccagatgttc aatatcttca aaggcatcca agttaatggt cgcacccaat
    39001 tcacgtgcat aggcgtattc cttgtctgac gtgttgttgg aagagaacat aatctcagaa
    39061 cccagaaagt ccagtttatg gctcatcaaa agctctacat aactagagca gtccacacca
    39121 caaccttctt cttggagaat tttcaaaata gctggagttg gagtagcctt aactgcaaaa
    39181 tattccttaa agcccttgtt ccacgaaaag gcttggttga cggctcttgc cttctcacga
    39241 atccccttct catcatacaa gtgaaaggga gtcgggaact cggcaacaat cgcttctaac
    39301 tcttctctat taataaatgg tgttttcata agcttccttc tattctattt gaaaagaaag
    39361 gctgggacaa tcgttccaac ctttagttct atctcttatt tatcttcgtc aaagatattg
    39421 ccaacctcaa catcgatggc ttggttcttg acatcaatat tggttacctt caagagtgac
    39481 ttgtagtcaa actgcttttc acgttcttct tgggcattgt ccgcaaagac cgctacacct
    39541 gccagttctg agtcgaactc gcgcaagaga ctaatcatac cgttgaccgt tccgccacct
    39601 ttcaagaagt catccacaat caagacacgg ctgcctgcct taagactacg ttttgaaagg
    39661 aacattttct cgatacggtc accacttgaa cctgaaacat agttgacgct aacagttgaa
    39721 ccttcggtaa ttttcaggtc acggcgcaca atgacaaaag agacattgag gacattggca
    39781 actgcatttg caagtggcac acccttagtt gctacggtca taaccgcgtc aattttttgg
    39841 tccataaagc ttttggcaat aatacgacca atatttttca agatggctgg tgtgctaagc
    39901 aaatcagaca gatagatata accacctggc aagatacggt cactttctga caacttggta
    39961 cgcaagtctt caaccatttc cttagcatcc tgactcgaaa tagacggtgt gaagatgaca
    40021 cctccgccag ccccagtcac tgtctggata tgaccgattt caatttcctc aaaggcgcgt
    40081 ttgataatga cgatatcttc tgagatggat gatttagcag actcatactt ttcagcaaaa
    40141 gtattgagac tagttagttt ataaggatta ttaatcaaat agttggaaat gacaaccatc
    40201 cgatcacttc ttcttaattt catttctatt tcctattcca tttttattca aaaaatcaaa
    40261 aagcaaacta aaaagctggt cgctggtggt tcaaaacact gttttgagat tgtcgataga
    40321 actgacaaac cctgtaatat acctgcatat atacatacga caaggcgata ctaccctagt
    40381 ttgaagagat tttcgaagag tattcatttt tgtcttttac ttattatacc atattcacat
    40441 aaaaaaacga acattcttat cctaaaaaat gctcattttt cttaaattat caatctaaat
    40501 ctggtttata gaaggaacga ttatccatag cgaagatttt attggtcatc tctcctttat
    40561 ccaccaaagc cagagctgtt gacatcatca tcatgcttgc atccagattg tcaatcatat
    40621 ggataatctc tgcctccata atacgtggac ggactggact tccatactca agcaagccgt
    40681 ggtgactgag gatgacatga cgaagcaaaa cgacttcttc cttggtatca tcgatgccga
    40741 gttccataac tgtcttggta atttcgctat caatgagagc gatatgtcca agaagattac
    40801 ctcgcactgt gtactctgtc tggtctggcc ccgtcaactc gataacctta gctaagtcat
    40861 gcagcataat ccccgcatag agcaggctct tattgagctg aggataaact tcgctaatag
    40921 cgtctgccaa acgtaccatg gtcgccgtat gataagccaa ccccgtttca aaggcatggt
    40981 ggttggtctt ggcagctgga taggagtaga attccttatc atacttggtg tagagatttc
    41041 ggacaatccg ttgccagaca ggattttcaa ttttgaaaat catttgcgac atgtagtcac
    41101 gaatttcctt gacatcaact ggtgacttga ccttgaaatc ggctgggtca ttgggttcac
    41161 cagcttgagg caggcggaga gtaatttgat tgacttgagg ggtattgtta taaacttctc
    41221 ggcgtccttt catgtggaca accttacctg cggtaaaggc ctcaatgtta tgaggttggg
    41281 catcccagag cttcccatca atctcgccac tatcatcttg gaaggtaaag gctaggtagt
    41341 ttttcccagc tcgagtttgc ctcaggtcag ctgatttgat taggtaaaag ccttcaaata
    41401 gctcatcttt tttcatgtga ctaatcttca tattcttcct cattttcttg aaaatggagt
    41461 agatcaagcg caggctcacc ttctgacaac tcaatgtgac ggagcgtccg ctcgatagct
    41521 atggtacgac ggtttaataa ttcatcaata ttgccagagg catgttggag atgtttttgt
    41581 gccttgacca gaataccacc aaacttgcca aactcggtct tgacactggc aagagtcttg
    41641 ctgatatggt cggcactctt ttggatatta agggtcttga aaccaactga tagggagtta
    41701 agaagggctg atagggtact tggtcctgca acgataatct gttcttcccg tctcaaatca
    41761 tcaaagaaga ccggattgcg cacaatctct gaataaagac cttctgtcgg aacaaacaag
    41821 attccaaaat tggttgtccg aggcggtgct atgtacttgc tcttgatatc cttggcaaag
    41881 cgcttgacgc ttgctaggag tgacttacga cagcgttcaa tctcatcctt gtcacctgtc
    41941 tcataggctt cttccaagcg gtaataatct gccagtggaa acttagagtc aattggcaga
    42001 tagacgtatt cttggtcgcc ttgtccgggt aacttgatgg catactccac tcgttcacta
    42061 gagttttcaa ccgttgcgta ttctcgttcg tactgggcag gtgtcatgat gtcttcaata
    42121 atttgcccca gttgcaattc tcccagaata cctcgcgtct tggttccaga gagaaccttg
    42181 ttaagagctc cgacatcacg ggcaactgtc tgcatttctc caaggccacg attgacagac
    42241 tccagttgtt tagaaactgt ttcaaaggaa gcctgtaagc gtgtctgcaa ggtcttttct
    42301 agtttttcct cgaccgtctg gcgcatttgt tccaaacgtt gctcatttga ttcctgcaag
    42361 gcttggagac gttggtctgt cttatctcta gtttggagga gattatctgt catttcttga
    42421 cggacttggg tcaggccttg gtgcaattca atccgcactt cttgcaaacg gtcgctgaca
    42481 gccacttcca aatctttttg gtctaactgg ctggcttgtc tggcttggtc aaagcggtaa
    42541 tccaactggt ctgacaaatg atctgcctga tcctccaagc tcttacttaa gtgtttctcc
    42601 tgcctatcct gcctttgcca aatcagaaag agaccagcta ggttggcaat taataataga
    42661 ataagtaaac tttccatcct acctcctgtc cttgctatgc agtacgacca cataaccatc
    42721 tgggcaagtt accgacactt ccctatctat atattcgtta gaagcgtaca cttttttaaa
    42781 gaaaaaattc tcctctgtca actcatactt agctccaaga atagtcagct ggctatcccg
    42841 aactggcata aaggctagat agtcgtagtc tgaacgaggt tctagctgac tggtcccttc
    42901 tgaacaatag gcaatcaaat tttgcccatc ctcaatttct atttgacgca tatagggtgc
    42961 caacttagga ttgctaggta gaaagacatt ggccaacata tggtcaatac ggccacccaa
    43021 ggcaccgaaa atagtgacct gagcctgagg attttgttca aagatggtta agagagccaa
    43081 ttccagatct gtatcatcct tttctggtcg ggcttggaca aaatactggg cacgtttttg
    43141 aatcacctgt cgctcttctt ccgtcacaga atcaaaatct ccgactgcta gagcaagagg
    43201 taagtcttct tccaagaccc agagcgagcc tcgatccacc ccaacaaaag catcaaaatc
    43261 tgtccgataa tgaccgcggt ttccgcctgc aaaaactgca accctagtcc agttgttttc
    43321 tgagagtttg tactcgctca ttgacttctc ccttaaagac ataggaacct gctacaaaaa
    43381 cagtcgcacc agcttctttg gcttgagcaa tagtttggtc atcaatccca ccatccactt
    43441 cgatttcaaa gttcaaacct ttttcctcac gaagagcaac caactcacga accttatcca
    43501 tggtttctgg cagaaaggct tgcccaccaa aacctggatt aaccgtcatg actaaaactt
    43561 ggtcaactag atgaaggacg tgcttgatgg cttcaactgg tgtgccagga ttgataacga
    43621 ctgaaggctt aactccgagt gaacgaattt tttggagggc gccatgaata tgaggtgttg
    43681 cttctacatg gatactgatg atgtctgcac ctgcacgcgc aaaatcttcc agatgatgct
    43741 cagggtttga caccatcaag tggcaatcga aaaccatctt actatgagga cgaaggctct
    43801 cgaccacacc tgcaccaaaa ctgatttgcg gtacaaaatg actgtccatg atatcgatat
    43861 gggcatattc tgccccagtt gcttctagac gtttgatttc acgttcaaag ttggcataat
    43921 ctgctgccag aattgacgga gcaatcttgt attgagacat aggtttctcc ttattttgga
    43981 atttttttgc tgactttttt ataggtttct ctacgatttt caatttcact aaggaattgc
    44041 aggtaattgt caaaacggaa ggttgcaata acaccctctt caacagctgg tttgacggca
    44101 caagacggct catgggtatg ggtacaagta cggaacttac aatctcggct aacagtagca
    44161 atctctggga aagcctgatt gaggtcttca gcccttgata cttcatagtc caaggatgaa
    44221 aatcctggtg tatctgcgat tttacccccg ttgagattgt aaaaactaac agctcgagtg
    44281 gtatggcgac cgcgacctag actgtctgaa atttctcccg tttcaagatt gaggtctggt
    44341 gcgattttat tgagaagagt tgacttccca acacctgtct gccccataaa gaccgtaacc
    44401 ttgcctgtta acaaagacag gagttcctct ttactggtca caaagtcata gccgatgtca
    44461 ccataggtct gctggtaaaa atccagttct cccctatctt ccaacaaatc cattttggaa
    44521 atatagacaa tgggatggat gcccttgtgc tccaaaagaa ccaagaaacg atccagcaaa
    44581 ttgctgttaa aatcaggttc cttgacggac atgattacta cagcttgatc gatattgaca
    44641 ataggcggac gaaccagact gtttttccgt tcgtgaattt tgaggatata gccttctgaa
    44701 ttttcctcgg cagagaaatc tacccagtcc ccaacataag gggtatggcc ttttttacgg
    44761 aaattcccac gcgcgcgtgt ttgataaacc tggccatcac tctccacata gtagaaacct
    44821 gccaaggctt taatgatttg tccctgcatc ttagagtcct tgccctttaa gtgcgtctgc
    44881 tagaccggca aattctgcca agctgagagc ttccccacgc acacttggtg acaagcctgc
    44941 ctggtccaaa gccttggtca gcttgtcctt gacctcttca gtcttaccaa agtaacctgt
    45001 caagttattc cacaaggtct tgcggcgatg ggtaaaacta gccttggaaa ccttaaagaa
    45061 aaagttctca tcttctactg ctacggctgg ctctggacga cgcaccattt tcaagatggc
    45121 tgaatccaca tttggtgctg gcacaaagac cgtacgaggc acgataaagg caaccttggc
    45181 tgtcatgtaa tactgcacgg cgatagacaa gctaccgtaa gccttggtgt taggctgggc
    45241 tgaaatgcgg tccgctactt ctttctgcat catgaccaca aactcacaaa aaggaatgcc
    45301 actctcaatc aagtgcatga gaataggcgt cgtgatgtag taaggcaaat tagccactac
    45361 cttgattggc aggttaggat ttttaaaatt ttggatatgt tgcgccaaat caaccttgag
    45421 aatatcttcg ttaactacag tcacattatc aaaatcacgc agggtatctg ccaaaattgg
    45481 caccaaacgg tggtcaatct caaaagccat gacttgggct gcacgctcag ccagaaactc
    45541 cgtcaaggca ccaatacctg gcccgatttc gatgacattg acctggtcat caatttcagc
    45601 cgtatccaca attttttgaa ggatattggt atccgtcaga aaattttgcc cgaaggactt
    45661 tttaaaggta aaaccgtgac gctccagcac tgccttggtc acgctataat ctgcaattct
    45721 catctattct cttttctatt atctgttact actattgtaa cacattcccc ttgtattttg
    45781 ggaatgaaaa tcataccaaa aaactatctt tcctcatgaa gaaagatagt cttggaaatc
    45841 tttaaaagtg gccttaacag ttctctcgaa acatgcgttc atactcttcg aaaatctctt
    45901 caaaccacgt cagcttcacc ttgccgtact caagtacagc ctgcggctag cttcctagtt
    45961 tgctctttga ttttcattga gtatcaaaaa aatcagcttc ttgataactt ctattttcgg
    46021 gtagggtcaa atccacatcc tcctccacat catccactgt cagttcaacc gtttgaggta
    46081 aatttttcaa acgataatgc ttttgccttt gcccttcaat actagcaaaa tcaagcaaat
    46141 agccatgcac taggatttga accaaaagga gatgattggt catattttcc atgatgagga
    46201 tatcttctaa accacctctg gcactaggat aatcagatac cctgcgaata cggatttttt
    46261 cacacatgag caagtttcct catatcaatg atttcatcag ccttattcca gactagggga
    46321 ttatgggtcg caatgatgat aattcgattt tcatctttca aatccaccaa gagattcata
    46381 acctcctctg aattttcagg atcaagagct gctgttggtt catctgccaa aatcaagggt
    46441 ggatttttca aaatagtctt agcaagggca actcgttggg cctctccccc agataaagta
    46501 tagatttttt gttctaaatc caaataccct agattaactt tttctaaagc ccccacttgc
    46561 ttttccaaac gttctacttt tgagattttc tgaccaacaa aacccaaatc caaattttct
    46621 ttgattgatt ggttttctaa gaggccgaaa ttttgaaaga gatagcccat ctggtctcga
    46681 aaatactcac gagtgggaat ggtttttaaa tctttcccct gatagagaac ccttccacca
    46741 tctatctttt ctagctttcc caagatattc agcagcgtcg tctttccgct tccactcttt
    46801 ccgattaagg cataaacctt gcccttctcc agcttgagat tcaaaccaga gaaaatcgcg
    46861 cggtcattaa atttcttttc caatccttga atatcaatca tcttattttc ctttcaatac
    46921 tgccatgcta ccagcttctt cttttttgtc ctgccttact aaaatcaaga gggcgttaag
    46981 cgtaaacaaa gctacaacta gagcgctaat caaaccatct cttgtcaaaa tactagatag
    47041 gactaggcca agcaagagaa ctcctccttg cgccagtaaa tacttgccat gaagctcata
    47101 gattgtcata ccagcaagac gtttaatcat aagctcccgt ctgaactgct caaaatagag
    47161 aagattcatg gaatcaaata acaagatagc cgtagacagg gtcaaaatcg tcccaataag
    47221 gagagagtaa aactctaccc gtttgtcatt tagtaccttg gcaaaaaata gctggctttt
    47281 taccaagtaa gaaaccttgt gatacagacc ttgctctttt agagctgtga tgctgtctcc
    47341 atatcgatct agtttcaagg cactattagc cgtagttccc cacaacatcc ctgcaacagg
    47401 tcttgttcca gtcgcttgcg gcgttagaac tacaataatc ggatctttta ggtactggcg
    47461 tgttgtcttg tacccatcat tatagaggaa acgttcctgt cctgtttctg taaaagctag
    47521 acttacctgt gggaggtagt atttctgact cgtcacttct acactttcag atgaaaagtt
    47581 ttgcaggtaa tctgtaaaca atctttggta gtaggtagac tgctctcgca agctctcagg
    47641 caagattagc ccaaactctc cctcagacaa gttttgcatc ttgtccataa actctgaaga
    47701 aacggtaatc ttttcttcta tcagatagcg tggtgagaca tagataacat tccctgacgg
    47761 tgtgtagtca ctgagacgat tgccatctag gtccacttct gctccatctg agaaattgtc
    47821 aacattgctc ataatataaa aagagtctgt attggctaac cgttcttcag taaatgtctg
    47881 ccactcacga ttatccttac gcgttccttc ttcatcggca aatgcactag accaaccaaa
    47941 ggatagacgg taacggtctg aggactggct ccatttattg ctagctctct ccatttcctg
    48001 catttcacgg tagtggggta ggagagctgt cgcactcgat ccgaccacca atacagctaa
    48061 gagttgcccc accatcatca atgtcatcat acgtttgaga gggagtttcc cttt
//
LOCUS       DAVHSI010000016        45999 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.016, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000016 DAVHSI010000000
VERSION     DAVHSI010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.016"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..209
                     /gene="tnpB"
                     /locus_tag="VVR21_000992"
     CDS             <1..209
                     /gene="tnpB"
                     /locus_tag="VVR21_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6054893.1"
                     /translation="AYVVKTHFELDSFSGQVFLFCGGRKDRFKALYWDGQGFWLLYKR
                     FENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(382..690)
                     /locus_tag="VVR21_000993"
                     /pseudo
     CDS             complement(382..690)
                     /locus_tag="VVR21_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            681..1079
                     /locus_tag="VVR21_000994"
     CDS             681..1079
                     /locus_tag="VVR21_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6054894.1"
                     /translation="MKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEIANWHIKASQYYLEPLYNLLRERLLTQSLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(1276..2196)
                     /gene="cysK"
                     /locus_tag="VVR21_000995"
     CDS             complement(1276..2196)
                     /gene="cysK"
                     /locus_tag="VVR21_000995"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU6054895.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(2481..3116)
                     /locus_tag="VVR21_000996"
     CDS             complement(2481..3116)
                     /locus_tag="VVR21_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU6054896.1"
                     /translation="MEFRTIKEDDQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            3172..4470
                     /locus_tag="VVR21_000997"
     CDS             3172..4470
                     /locus_tag="VVR21_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6054897.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            4467..5129
                     /locus_tag="VVR21_000998"
     CDS             4467..5129
                     /locus_tag="VVR21_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU6054898.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            5208..5756
                     /gene="raiA"
                     /locus_tag="VVR21_000999"
     CDS             5208..5756
                     /gene="raiA"
                     /locus_tag="VVR21_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU6054899.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRLKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QITNVIYRREDGEIGLLEVKES"
     gene            5892..7865
                     /locus_tag="VVR21_001000"
     CDS             5892..7865
                     /locus_tag="VVR21_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU6054900.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLIEIVLNEIKEKEKEE"
     gene            7862..8314
                     /gene="rplI"
                     /locus_tag="VVR21_001001"
     CDS             7862..8314
                     /gene="rplI"
                     /locus_tag="VVR21_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU6054901.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            8357..9709
                     /gene="dnaB"
                     /locus_tag="VVR21_001002"
     CDS             8357..9709
                     /gene="dnaB"
                     /locus_tag="VVR21_001002"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU6054902.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9711..9977
                     /locus_tag="VVR21_001003"
     CDS             9711..9977
                     /locus_tag="VVR21_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054903.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            10066..11184
                     /gene="cbpD"
                     /locus_tag="VVR21_001004"
     CDS             10066..11184
                     /gene="cbpD"
                     /locus_tag="VVR21_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU6054904.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     VKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSHSSSTV
                     GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAM
                     KTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      11267..11369
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11440..11730
                     /locus_tag="VVR21_001005"
     CDS             11440..11730
                     /locus_tag="VVR21_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU6054905.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11693..12451
                     /locus_tag="VVR21_001006"
     CDS             11693..12451
                     /locus_tag="VVR21_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6054906.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            12489..13496
                     /locus_tag="VVR21_001007"
     CDS             12489..13496
                     /locus_tag="VVR21_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6054907.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13496..14224
                     /locus_tag="VVR21_001008"
     CDS             13496..14224
                     /locus_tag="VVR21_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6054908.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            14343..14801
                     /locus_tag="VVR21_001009"
     CDS             14343..14801
                     /locus_tag="VVR21_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU6054909.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            14803..17235
                     /locus_tag="VVR21_001010"
     CDS             14803..17235
                     /locus_tag="VVR21_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6054910.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMAHMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKANHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17877..18530
                     /gene="rr06"
                     /locus_tag="VVR21_001011"
     CDS             17877..18530
                     /gene="rr06"
                     /locus_tag="VVR21_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU6054911.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMILDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            18527..19858
                     /gene="hk06"
                     /locus_tag="VVR21_001012"
     CDS             18527..19858
                     /gene="hk06"
                     /locus_tag="VVR21_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU6054912.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            19941..20468
                     /locus_tag="VVR21_001013"
     CDS             19941..20468
                     /locus_tag="VVR21_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU6054913.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            20547..22535
                     /gene="cbpA"
                     /locus_tag="VVR21_001014"
     CDS             20547..22535
                     /gene="cbpA"
                     /locus_tag="VVR21_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HEU6054914.1"
                     /translation="MFASKNERKVHYSIRKFSIGVASVAVASLFMGSVVHATENEGTT
                     QVATSSNKANKSQTEHMKAAKQVDEYIKKMLQLDRRKHTQNVGLLTKLGAIKTEYLHG
                     LSVSKEKSEAELPSKIKAELDAAFENFKKDTLKPGEKVAEAKKKVEEAELELVKEEAK
                     EPRDEEKIKQAKEKVESKKAEATRLENIKTDRKKAEEEAKRKADAKLKEANVATSDQG
                     NPKGRGKRGVPGELATPDKKENDAKSSDSSVGEETLPSSSLKSGKKVTEAEKKVEEAE
                     KKAKDQKEEDRRNYPTNTYKTLDLEIAESDVKVKEAELELVKEEAKEPRDEEKIKQAK
                     EKVESKKAEATRLEKIKTDRKKAEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPK
                     PEKPAEQPKAEKTDDQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQEN
                     GMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGAMATGWLQ
                     NNGSWYYLNSNGAMATGWLQYNGSWYYLNANGDMATGWLQNNGSWYYLNANGAMATGW
                     AKVNSSWYYLNANGAMATGWAKVNSSWYYLNANGDMATGWVKDGDTWYYLEASGAMKA
                     SQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(22765..23745)
                     /gene="dusB"
                     /locus_tag="VVR21_001015"
     CDS             complement(22765..23745)
                     /gene="dusB"
                     /locus_tag="VVR21_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU6054915.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(23732..24604)
                     /gene="hslO"
                     /locus_tag="VVR21_001016"
     CDS             complement(23732..24604)
                     /gene="hslO"
                     /locus_tag="VVR21_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU6054916.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            24769..26196
                     /locus_tag="VVR21_001017"
     CDS             24769..26196
                     /locus_tag="VVR21_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6054917.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRNLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLVDLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            26355..27863
                     /gene="glpK"
                     /locus_tag="VVR21_001018"
     CDS             26355..27863
                     /gene="glpK"
                     /locus_tag="VVR21_001018"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU6054918.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTTIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            27905..29731
                     /gene="glpO"
                     /locus_tag="VVR21_001019"
     CDS             27905..29731
                     /gene="glpO"
                     /locus_tag="VVR21_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU6054919.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            29801..30505
                     /locus_tag="VVR21_001020"
     CDS             29801..30505
                     /locus_tag="VVR21_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6054920.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            30802..31005
                     /locus_tag="VVR21_001021"
     CDS             30802..31005
                     /locus_tag="VVR21_001021"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054921.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(31092..31598)
                     /locus_tag="VVR21_001022"
     CDS             complement(31092..31598)
                     /locus_tag="VVR21_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054922.1"
                     /translation="MRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMA
                     YQKNEIDLNISFRSYDPNVWNYVNTIHGNKQANTFANFMTGAGISYMIGRIGALLGGP
                     WGAIIGGAYFGIQAYQSYLDSQSPYPYYITSTYIHVVQRKWKFITEYYRNSNYTGYVK
                     TVTTYVNF"
     gene            32775..34052
                     /gene="ltrA"
                     /locus_tag="VVR21_001023"
     CDS             32775..34052
                     /gene="ltrA"
                     /locus_tag="VVR21_001023"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEU6054923.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            34508..35686
                     /locus_tag="VVR21_001024"
     CDS             34508..35686
                     /locus_tag="VVR21_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6054924.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            36010..36141
                     /locus_tag="VVR21_001025"
     CDS             36010..36141
                     /locus_tag="VVR21_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU6054925.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            36162..37712
                     /gene="dltA"
                     /locus_tag="VVR21_001026"
     CDS             36162..37712
                     /gene="dltA"
                     /locus_tag="VVR21_001026"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU6054926.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKSDSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GQPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMIPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            37709..38953
                     /gene="dltB"
                     /locus_tag="VVR21_001027"
     CDS             37709..38953
                     /gene="dltB"
                     /locus_tag="VVR21_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU6054927.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            38967..39206
                     /gene="dltC"
                     /locus_tag="VVR21_001028"
     CDS             38967..39206
                     /gene="dltC"
                     /locus_tag="VVR21_001028"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU6054928.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            39199..40467
                     /gene="dltD"
                     /locus_tag="VVR21_001029"
     CDS             39199..40467
                     /gene="dltD"
                     /locus_tag="VVR21_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU6054929.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            40622..41062
                     /gene="adcR"
                     /locus_tag="VVR21_001030"
     CDS             40622..41062
                     /gene="adcR"
                     /locus_tag="VVR21_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU6054930.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            41062..41766
                     /locus_tag="VVR21_001031"
     CDS             41062..41766
                     /locus_tag="VVR21_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU6054931.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            41759..42565
                     /locus_tag="VVR21_001032"
     CDS             41759..42565
                     /locus_tag="VVR21_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU6054932.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAVVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            42575..44080
                     /gene="adcA"
                     /locus_tag="VVR21_001033"
     CDS             42575..44080
                     /gene="adcA"
                     /locus_tag="VVR21_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU6054933.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(45208..45981)
                     /locus_tag="VVR21_001034"
     CDS             complement(45208..45981)
                     /locus_tag="VVR21_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6054934.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
BASE COUNT        13958 a         8228 c        10220 g        13593 t
ORIGIN      
        1 tagcctatgt agttaaaacc cactttgaat tggattcttt ctccggtcaa gtctttctct
       61 tttgtggtgg acgtaaagac cgctttaaag ccctttactg ggatggtcaa ggattttggc
      121 tactatataa acgctttgag aacggaaaac tgacttggct aagtacagaa aaggatgtca
      181 aagctctcgc acctgaacaa gtagactagc ttatgaaggg cttttctatc actccaaaaa
      241 tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt agaaatcgat
      301 ttgtcctgtt cttatttcat tttactataa atccatcaga aagtcgtgat ttctattgaa
      361 atgaggactt tctttttatg ctcatctgtt ttcaaaaagc attctagtcc atctccgatt
      421 aacgatggac tttatcacct ccttctccag tccttgtata acatcttgga gttgattcat
      481 gacatcttcc aaagtttgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca
      541 cacttgttca atggggttca tctctggtgt gtatggagga ataaaggtaa aaccaatatt
      601 agtcggaatc tttaaggtac ttgatttatg ccatatagca ttgtccataa cgagtaaaag
      661 ataatcatct ggataagctt gtgaaagctc ctattcctaa agcccctttg gcgcatagcc
      721 ttggctcagc ttctattatc gctcacacca tccatcagaa gtttaatctg aaggtaccca
      781 attatcgcca agaagaagat tgggctaaga tgggtttacc aatcacacgt aaggaaattg
      841 ctaattggca tatcaaggcg agtcaatact atttggagcc cctttataac ctcttgcgag
      901 agagactatt gacgcagtcc ttacttcatg cggatgaaac ttcttatagg gtgctagaga
      961 gtgatagtca gctgacttac tattggactt ttttgtctgg gaaagctgag aaacaaggga
     1021 ttacgcttta ccatcatgtc ctaatcgatt tgttcatatc ttatttcaat ccattataaa
     1081 tagtgagaaa tatttatcct atcttctaga atgtcttcca aacgtggaaa ctctcgtaaa
     1141 caaagaggtt ttagaggcct atttaccatg gactaaagtt gtacaagaaa agtgcaaata
     1201 agaaatctcc agattaggaa ctatccgtga gttctctagt ctggagattt ttcaatatac
     1261 ttcgttattg gatggttaca attcataaag tgctgtagag agataacgtt caccgttatc
     1321 tggtgctagg gcaaggactt ttttacctgt acctaatttt ttggcaacct cgatggctcc
     1381 gtagatagct gcagctgagg aaatccctac aaggaagcct tcttttccac caatttcacg
     1441 tccgagtgca agagcgtcat ctgatgttac acgaacgata ccatcatagg ctttagtatc
     1501 aagtgtatca ggaataaatc cagctgagat accttgaatt ttgtgaggac caggtttttc
     1561 accagataga atagcagatt catctgcttc tactgcaaaa acttgaatgt tagaattttc
     1621 tgatttgagt gcatgagaaa caccagaaat cgttccaccg gtacctactc cagcaacaaa
     1681 ggcatctaat ccatctttac cgaaagcagc tagtatctca gctcctgttg ttctttcgtg
     1741 tacttctgga ttagctggat tgtcaaattg aagaggaagg aaaccatcac gttcagcagc
     1801 gatttcttga gccttagcaa tagcaccttt cattccctcg ctaccaggag ttaggacgag
     1861 ttcagcacca taagcttgga taattttacg tcgttctaca ctcatagttt caggcataac
     1921 gatgacgact ttataccctt tagcagcacc tacccatgaa agtccaatac cagtgtttcc
     1981 acttgttgct tcaacaatag tagaaccagg tttcagaata ccatcttgtt cagctttttc
     2041 aatcatgcta agggcaatac ggtcttttac agatgaacca ggattaaatg cttcaagctt
     2101 tatatagacg tctgcagcac cttctggcac gatgttgtta agtttaacaa tcggtgtttg
     2161 accgattaat tcagtaatgt tgttataaat agacatacga atacctcttt gtataagata
     2221 tctttagtat aacgctatcc ataccatttg taaaatatag aaatcctatc gaagcgatag
     2281 gatttctata tatcatagat caaagtcatt aattttcaag tgattgcgtt cagctaattc
     2341 tagtaaatag gtgtgaagga aaacgatatc aggtttcgtt tgaattgctt cattttctag
     2401 tatattttgg tacgcatctt tttattttgc tcgctaaagt agttgtgaga atgtcaacga
     2461 aacgctgtat tattcattgt ttacactaag tttacaggaa cttcaacctc tcgtaaacct
     2521 tggtcagtta aagtgacttt tccattaaaa aactccacaa gtgcagcttt aatagtttct
     2581 ttttcttctt tatcaacata aatcatcgta tcgacttgat ctgtaaagtt tgtatccagc
     2641 tccatgagat catgttcttt aaggaagtta ctgtactctt ggtactgagc ataagacatt
     2701 tgaatagcaa tgccagcctg ttcttttatt tcaataatac caatttcttt gacagctaag
     2761 gcgacactgc cggcgtaagc acgaattagt cctccagcgc ctagtttaat accaccaaag
     2821 tagcgtgtca cgaccacaca gacattggtg agattgtgat tttctagtac cccaagcatg
     2881 ggaacaccag cagtaccact aggctcacca tcatcacttg tacgtttaat ttcactacgt
     2941 tctccaataa taaaggcaga gcagttatgt gtcgctttgt agtgttcttt tttgatggca
     3001 gtaatgaagt cacgagcctc ttcttcgcta taaacacgct tggcatggca gataaagcga
     3061 gattttttga tttcttcttg gacttggtcg tcctctttaa ttgttctaaa ttccatgatt
     3121 taattgtact aaaaaatcat ctaaagtgct agtttttacg aataaagaag tatgaaagta
     3181 aatttagatt atctcggtcg tttatttact gagaatgaat taacagaaga agaacgtcag
     3241 ttggcggaga aacttccagc aatgagaaag gagaagggga aacttttctg tcaacgttgt
     3301 aatagtacta ttctagaaga atggtatttg cccatcggtg cttactattg tcgagagtgc
     3361 ttgctgatga agcgagtcag aagtgatcaa actttatact attttccgca ggaggatttt
     3421 ccgaagcaag atgttctcaa atggcgcggc caattaactc cttttcaaga gaaggtgtca
     3481 gagggactgc ttcaagcagt agacaagcaa aagccaacct tagttcatgc ggtaacagga
     3541 gctggaaaga cagaaatgat ttatcaagta gtggctaaag tgatcaatgc gggtggtgca
     3601 gtgtgtttgg ctagtcctcg catagatgtt tgtttggagc tgtataagcg cctgcaacag
     3661 gatttttctt gcgggatagc tttgctacat ggagaatcgg aaccttattt tcgaacacca
     3721 ctagttgttg caacaaccca tcagttattg aagttttatc aagcttttga tttgctgata
     3781 gtggatgaag tagatgcttt tccttatgtt gataatccca cgctttacca tgctgtcaag
     3841 aatagtgtaa aggagaatgg attgagaatc tttttaacag cgacttcgac caatgagtta
     3901 gataaaaagg tccgtttagg agaactaaaa agactgaatt taccgagacg gtttcatgga
     3961 aatccgttga ttattccaaa accaatttgg ttatcggatt ttaatcgcta cttagacaag
     4021 aatcgtttgt caccaaagtt aaagtcctat attgagaagc agagaaagac agcttatccg
     4081 ttactcattt ttgcttcaga aattaagaaa ggggagcagt tagaagaaat cttacaggag
     4141 caatttccaa atgagaaaat tggctttgta tcttctgtaa cagaggatcg attagagcaa
     4201 gtacaagctt ttcgagatgg agaactgaca atacttatca gtacgacaat cttggagcgt
     4261 ggagttacct tcccttgtgt ggatgttttc gtagtagagg ccaatcatcg tttgtttacc
     4321 aagtctagtt tgattcagat tggtggacga gttggacgaa gcatggatag accgacagga
     4381 gatttgcttt tcttccatga tgggttaaat gcttcaatca agaaggcgat taaggaaatt
     4441 cagatgatga ataaggaggc tggtctatga agtgcttgtt atgtgggcag actatgaaga
     4501 ctgttttaac ttttagtagt ctcttacttc tgaggaatga tgactcttgt ctttgttcag
     4561 actgtgattc tacttttgaa agaattgggg aagagaactg tccaaattgt atgaaaacag
     4621 agttgtcaac aaagtgtcaa gattgtcaac tttggtgtaa agagggagtt gaagtcagtc
     4681 atagagcgat ttttacttac aatcaagcta tgaaggattt tttcagtcgg tataagtttg
     4741 atggagactt cctgttaaga aaagttttcg cttcattttt aagtgaggag ttgaaaaagt
     4801 acaaagagta tcaatttgtt gtaattcccc taagtcctga tagatatgct aatagaggat
     4861 ttaatcaggt tgagggcttg gtagaggcag caggctttga gtatctggat ttattagaga
     4921 aaagagaaga gagagccagt tcttctaaaa atcgttcaga gcgcttgggg acagaacttc
     4981 ctttctttat taaaagtgga gtcactattc ctaaaaaaat cctacttata gatgatatct
     5041 atactacagg agcaactata aatcgtgtta agaaactgtt ggaagaagct ggtgctaagg
     5101 atgtaaaaac attttccctt gtaagatgag gaaaaatttg caaaaataga atgaaagcgt
     5161 tataataaaa tcataaaaac aaaaatgttt agaaagaagg tactcatatg attaaatata
     5221 gtatccgtgg tgaaaaccta gaagtaacag aagcaattcg tgattatgta gtttctaaac
     5281 tcgaaaagat cgaaaagtac ttccaaccag aacaagagtt ggatgcccga attaacttaa
     5341 aagtttatcg tgaaaaaacg gctaaagtgg aagtaacgat tccgcttgga tctattactc
     5401 tccgcgcaga agatgtatct caagatatgt atggttcaat tgaccttgta actgataaaa
     5461 ttgaacgtca gattcgtaaa aataaaacaa aaatcgagcg taaaaataaa aataaggtag
     5521 caactggtca attatttaca gatgctttgg tggaagattc aaatgttgtc cagtctaaag
     5581 ttgttcgttt aaaacaaatt gatttaaaac caatggattt ggaagaagca attctacaaa
     5641 tggatttatt ggggcatgat ttctttatct atgtggatgt tgaagatcag ataaccaatg
     5701 tgatttatcg tcgtgaggat ggcgaaattg gtttgttaga ggttaaagaa tcttaatttc
     5761 aatatgtgta aaggtaggtt tactgaattg taaactacct ttttcttata attgatagaa
     5821 ttactgatta cacttttaaa aagtcgcttt ttgaggggta ttatggtata atgggtgcca
     5881 agaggttttg aatgaaaaaa ttttatgtaa gtccaatttt tcctattcta gtaggattga
     5941 ttgcgtttgg agtcttatcc actttcatta tttttgttaa taataatctg ttgacggttt
     6001 taattttgtt tctttttgta ggaggctatg tttttttatt taagaaactg agagtgcatt
     6061 atacaaggag tgatgtagaa cagatacagt atgtaaacca ccaagcggaa gaaagtttga
     6121 catctctatt ggaacaaatg cctgtaggtg ttatgaaatt gaatttatct tctggagagg
     6181 ttgagtggtt taatccctat gctgaattga ttttgaccaa ggaagatggt gattttgatt
     6241 tagaagctgt tcaaacgatt atcaaggctt cagtaggaaa tccgtctact tatgccaagc
     6301 ttggtgagaa gcgttatgct gttcatatgg atgcttcttc cggtgttttg tattttgtag
     6361 atgtatccag ggaacaagcc ataacagatg aattggtaac aagtcgacca gtgattggga
     6421 ttgtctctgt ggataattat gatgatttgg aggatgcaac ttctgagtca gatattagtc
     6481 aaatcaatag ttttgtagct aattttatat cagagttttc agaaaaatac atgatgtttt
     6541 ctcgtcgggt aagtatggat cgattttatc tatttactga ctacacggtg cttgagggct
     6601 tgatgaatga taaattttct gttattgatg ctttcagaga agagtcgaaa cagagacagt
     6661 tgcccttgac cttaagtatg ggattttctt atggcgatgg aaatcatgat gagataggga
     6721 aagttgcttt gctcaatttg aacttggctg aagtacgtgg tggcgaccag gtggttgtta
     6781 aggaaaacga cgaaacgaaa aatccagttt attttggtgg tgggtctgct gcttcaatca
     6841 agcgtacacg gactcgtacg cgcgctatga tgacagctat ttcagataag attcggagtg
     6901 tagatcaggt ttttgtagtc ggtcacaaaa atttagacat ggatgctttg ggctctgctg
     6961 taggtatgca gttgttcgcc agcaatgtga ttgaaaatag ctatgctctt tatgatgaag
     7021 aacaaatgtc tccagatatt gaacgagctg tttcattcat agaaaaagaa ggagttacga
     7081 agttgttgtc tgttaaggat gcaatgggga tggtgaccaa tcgttctttg ttgattcttg
     7141 tagaccattc aaagacagcc ttaacattat caaaagaatt ttatgattta tttacccaaa
     7201 ccattgttat tgaccaccat agaagggatc aggattttcc agataatgcg gttattactt
     7261 atatcgaaag tggtgcaagt agtgccagtg agttggtaac ggaattgatt cagttccaga
     7321 attctaagaa aaatcgtttg agtcgtatgc aagcaagtgt tttgatggct ggtatgatgt
     7381 tggatactaa aaatttcacc tcgcgagtaa ctagtcggac atttgatgtt gctagctatc
     7441 tcagaacgcg cggaagtgat agtattgcta tccaggaaat cgctgcgaca gattttgaag
     7501 aatatcgtga ggtcaatgaa cttattttac aggggtgtaa attaggttca gatgtactaa
     7561 tagcagaggc taaggacacg aaatgctatg atacagttgt tattagtaag gcagcagatg
     7621 ccatgttagc catgtcaggt attgaagcga gttttgttct tgcgaagaat acacaaggat
     7681 ttatctctat ctcagctcga agtcgtagta aactgaatgt acaacggatt atggaagagt
     7741 taggcggtgg aggccacttt aatttggcag cagctcaaat taaagatgta accttgtcag
     7801 aagcaggtga aaaactgata gaaattgtat taaatgaaat aaaggaaaag gagaaagaag
     7861 aatgaaagta atctttttag cagatgttaa aggaaaaggt aaaaaaggcg aaattaagga
     7921 agtaccaaca gggtatgcgc aaaactttct tatcaaaaag aatctagcca aagaagcgac
     7981 tgctcaagct gtaggtgaac ttcgtggtaa acaaaaatcg gaagaaaaag ctcacgctga
     8041 gatgattgca gaaggaaaag caattaaagc acaacttgaa gcagaagaaa ctgttgtaga
     8101 atttgttgaa aaagttggtc cagatggtcg tacctttggt tctattacca ataagaagat
     8161 tgcagaagaa ttgcaaaagc aatttggaat taagattgat aaacgtcata ttcaagtaca
     8221 agctccgatt cgagcggttg gtttgattga tgtgccagtg aaaatctatc aagatatcac
     8281 aagtgtaatc aatcttcgtg tgaaagaagg ataagtttac actttcttga caagattgta
     8341 aaagaaggga agtctgatgg cagaagtaga agagttacga gtacaacctc aagatatctt
     8401 agctgagcaa tccgttttag gggctatctt tattgatgag agtaaacttg tttttgtgcg
     8461 agaatacatt gagtctcggg acttttttaa gtatgcccat cgtttgattt tccaagccat
     8521 ggtcgattta tccgatcgtg gtgatgccat agatgcaaca acggttcgta ctatccttga
     8581 taatcaaggt gatttacaga atattggtgg cttgtcttac ttggttgaga ttgttaattc
     8641 tgtgccaact tctgctaatg cggagtatta tgctaagatt gttgcagaaa aagcaatgct
     8701 acgtcgttta attgccaagt tgacagagtc tgtcaaccaa gcttacgaag cgtcacaacc
     8761 agctgatgaa attattgctc aggcagaaaa agggttgatt gatgtcagtg aaaatgcaaa
     8821 tcgaagcggg tttaagaaca ttcgagatgt gttgaatctc aactttggaa atctggaagc
     8881 tcgctcgcaa caaacgaccg atattacagg tattgcgaca ggttatcgtg atttggatca
     8941 tatgacaaca ggacttcatg aggaggagtt gattatctta gcagctcgtc cagcagttgg
     9001 taagacagca tttgccttga atatcgctca gaacattggg actaagttgg acaaaacggt
     9061 tgctattttt tcactcgaaa tgggtgcgga aagcttggta gatcgtatgt tagctgcaga
     9121 aggcttggtg gagtcacatt ctatccgtac agggcaattg acagatgagg agtggcaaaa
     9181 atatactatt gctcagggta atctagctaa cgccagtatc tatatcgatg atacgccagg
     9241 tattcggatt acagagattc gttctcgttc tcgtaaattg gctcaagaaa ctggaaatct
     9301 tggtttgatt ttgatagact atttgcaact tatcacggga actggtcgag aaaatcgtca
     9361 acaagaagtt tctgaaattt ctcgtcagtt gaaaatacta gccaaggaat tgaaggttcc
     9421 agtaatcgct ctgagtcagc tttctcgtgg tgtagaacaa cgtcaggaca agagaccagt
     9481 cttgtctgat attcgtgaat ctgggtctat tgagcaggac gctgatatcg tagcttttct
     9541 ctatcgcgat gactactatg aacgtggtgg tgaagaagag gagggtatcc caaataataa
     9601 ggtggaagtt attatcgaga aaaaccgtag tggagctcgt ggaacagtgg aattgatttt
     9661 ccaaaaagaa tacaataaat tttcaagtat ctcaaagagg gaggcataag atgtcagatg
     9721 catttacaga tgtagccaag atgaaaaaaa tcaaagaaga aatcaaggca catgagggac
     9781 aagtcgtaga aatgactttg gagaatggtc gtaagcgcca aaaaaataga ttgggtaagc
     9841 taattgaagt ttatccatct ctatttattg tggagtttgg ggatgtggaa ggagataaac
     9901 aagttaatgt ttacgttgaa tcctttactt actcagatat tcttacagaa aagaatttga
     9961 ttcattatct tgactaaagt gagaaatttt ctcacttttt cttttttctc cgaataattt
    10021 aggtgaaggc aatcatcgct ttatattatt tttcaaggag gaagaatgaa aattttaccg
    10081 tttatagcaa gaggaacaag ttattacttg aagatgtcag ttaaaaagct tgttcctttt
    10141 ttagtagtag gattgatgct agcagctggt gatagtgtct atgcctattc cagaggaaat
    10201 ggatcgattg cgcgtgggga tgattatcct gcttattata aaaatgggag ccaggagatt
    10261 gatcagtggc gcatgtattc tcgtcagtgt acttcttttg tagcctttcg tttgagtaat
    10321 gtcaatggtt ttgaaatgcc ggcagcttat ggaaatgcga atgaatgggg acatcgtgct
    10381 cgtcgggaag gttatcgtgt agataataca ccgacgattg gttccattac ttggtctact
    10441 gcaggaactt atggtcatgt tgcctgggtg tcaaatgtaa tgggagatca gattgagatt
    10501 gaggaatata actatggtta tacagaatcc tataataaac gagttgtaaa agcaaacacg
    10561 atgacaggat ttattcattt taaagatttg gatggtggca gtgttgggaa tagtcaatcc
    10621 tcagcttcaa caggcggaac tcattatttt aagaccaagt ctgctatcaa aactgaaccc
    10681 ctagttagtg caactgtgat tgattactat tatcctgggg agaaggttca ttatgatcag
    10741 atacttgaaa aagacggcta caagtggttg agttatacgg cttataacgg aagtcgtcgc
    10801 tatatacagc tagagggagt gacttcttca caaaattatc agaatcaatc aggaaacatc
    10861 tctagctatg gatcccatag tagttcaact gtcggttgga agaaaataaa tggtagttgg
    10921 tatcatttca aatcaaatgg ttctaaatca acaggatggc tgaaagacgg ttctagctgg
    10981 tattatttga aattatctgg tgaaatgcag acaggatggt taaaggagaa tggctcgtgg
    11041 tattatctgg gtagttcagg ggcaatgaaa acaggctggt accaggtctc tggtaagtgg
    11101 tattattctt actcttcagg cgccttagct gttaatacga cggtggatgg ctacagagta
    11161 aacagtgatg gagaacgagt atagaaaatt ggagtaggag aaatttcctg ctcttttctg
    11221 taagcagttt ccttgacatt tttcttattt tgcgctatca tatatacata taatatatgg
    11281 gagtctgtgt acagtctgag aggaagtgtt aaacttcgac cgcacctgat ctgggtaatg
    11341 ccagcggagg gaacgatact tagtctaatt ttgcaccttt tccatgtatg gtaaaggttt
    11401 ttcttttttt aaaaaggaaa acgagaagag gaggttctta tgaaagcaag cattgccttg
    11461 caagttttac ccctagtaca ggggattgat cggatagctg ttattgatca ggtcattgct
    11521 tatctgcaaa ctcaagaagt gacgatggta gtgacaccat ttgaaacggt cttggaaggg
    11581 gagtttgatg agcttatgcg cattctaaaa gaagcgctgg aagtggcagg gcaggaggca
    11641 gacaatgtct ttgccaatgt caaaataaat gtaggagaga ttttaagtat tgatgagaaa
    11701 cttgagaagt atactgagac gacacattag tctattgggc tttctcggag tattgtcaat
    11761 ctggcagtta gcaggttttc ttaaacttct ccccaagttt atcctgccga cacctcttga
    11821 aattctccag ccctttgttc gtgacagaga atttctctgg caccatagct gggcgacctt
    11881 gagagtggct ttactggggc tgattttggg agttttgatt gcctgtctta tggctgtgct
    11941 catggatagt ttgacttggc tcaatgacct gatttaccct atgatggtgg tcattcagac
    12001 cattccgacc attgccatag ctcctatcct ggtcttgtgg ctaggttatg ggattttgcc
    12061 caagattgtc ttgattatct taacaacaac ctttcccatc atcgttagta ttttggacgg
    12121 ttttaggcat tgtgacaagg atatgctgac tttgtttagt ctgatgcgag caaacccttg
    12181 gcaaatcctg tggcatttta aaatcccggt tagcctgcct tacttttatg caggtctgag
    12241 ggtcagtgtc tcctacgcct ttatcacaac tgtggtatct gagtggttgg gaggttttga
    12301 aggtcttggt gtttatatga ttcagtctaa aaaactgttt cagtatgata ccatgtttgc
    12361 cattattatt ctggtgtcga ttatcagtct tttgggtatg aagctggtcg atatcagtga
    12421 aaaatatgtg attaaatgga aacgtactta aaatagagcg tttttgaaaa agaaaagagg
    12481 aaatcaaaat gaagaaaaca tggaaagtgt ttttaacgct tgtaacagct cttgtagctg
    12541 ttgtgcttgt ggcctgtggt caaggaactg cttctaaaga caacaaagag gcagaactta
    12601 agaaggttga ctttatccta gactggacac caaataccaa ccacacaggg ctttatgttg
    12661 ccaaggaaaa aggttatttc aaagaagctg gagtggatgt tgatttgaaa ttgccaccag
    12721 aagaaagttc ttctgacttg gttatcaacg gaaaggcacc atttgcagtg tatttccaag
    12781 actacatggc taagaaattg gaaaaaggag caggaatcac tgccgttgca gctattgttg
    12841 aacacaatac atcaggaatc atctctcgta aatctgataa tgtaagcagt ccaaaagact
    12901 tggttggtaa gaaatatggg acatggaatg acccaactga acttgctatg ttgaaaacct
    12961 tggtagaatc tcaaggtgga gactttgaga aggttgaaaa agtaccaaat aacgactcaa
    13021 actcaatcac accgattgcc aatggcgtct ttgatactgc ttggatttac tacggttggg
    13081 atggtatcct tgctaaatct caaggtgtag atgctaactt catgtacttg aaagactatg
    13141 tcaaggagtt tgactactat tcaccagtta tcatcgcaaa caacgactat ctgaaagata
    13201 acaaagaaga agctcgcaaa gtcatccaag ccatcaaaaa aggctaccaa tatgccatgg
    13261 aacatccaga agaagctgca gatattctca tcaagaatgc acctgaactc aaggaaaaac
    13321 gtgactttgt catcgaatct caaaaatact tgtcaaaaga atacgcaagc gacaaggaaa
    13381 aatggggtca atttgacgca gctcgctgga atgctttcta taaatgggat aaagaaaatg
    13441 gtatccttaa agaagacttg acagacaaag gcttcaccaa cgaatttgtg aaataatgac
    13501 agaaattaga ctagagcacg tcagttatgc ctatggtcag gagaggattt tagaggatat
    13561 caacctacag gtgacttcag gcgaagtggt ttccatccta ggcccaagtg gtgttggaaa
    13621 gaccaccctc tttaatctaa tcgctgggat tttagaagtt cagtcaggga gaattgtcct
    13681 tgatggtgaa gaaaatccca aggggcgcgt gagttatatg ttgcaaaagg atctgctctt
    13741 ggagcacaag acggtgcttg gaaatatcat tctgcccctc ttgattcaaa aggtggataa
    13801 ggcagaagct atttcccgag cggataaaat tcttgcgacc ttccagctga cagctgtaag
    13861 agacaagtat cctcatgaac ttagcggtgg gatgcgccag cgtgtagcct tactccggac
    13921 ctaccttttt gggcacaagc tctttctctt agatgaggcc tttagcgcct tggatgagat
    13981 gacaaagatg gaactccacg cttggtatct tgagattcac aaacagttgc agctaacaac
    14041 cctgatcatc acgcatagta ttgaggaggc cctcaatctc agcgaccgta tctatatctt
    14101 gaaaaatcgc cctgggcaga ttgtttcaga aattaaacta gattggtctg aagatgagga
    14161 caaggaagtc caaaagattg cctacaaacg tcaaatcttg gcagaattag gcttagataa
    14221 gtagaaaaat agggagttgg tgaagattat cctttaccag cgcccttttt cttttaaaaa
    14281 tgagaaaatt tcggtataat agtcaaacaa ggtcaaggtt taaagagaga ggtgggtttg
    14341 ttatgagatt taaaaataca tcggatcata ttgaggccta catcaaggcg attttagatc
    14401 aatctggtat cgtggagttg caacggagtc agttggcaga tacctttcag gttgttccta
    14461 gtcagattaa ctacgtgatc aagacacgct ttacggaaag tagaggctac ttggttgaaa
    14521 gtaagcgtgg tggcggaggc tacattcgta taggacggat tgagttttct agtcatcatg
    14581 aaatgctccg ggagctgctt tactcgattg gtgagcgagt cagtcaagaa atttatgagg
    14641 atattctcca gcttttggtt gagcaggaat tgatgaccaa gcaggagatg aatttgctag
    14701 aatcagtagc tttggatcgc gttttaggag aagaagctcc agttgttcga gcaaacatgc
    14761 tacgtcaggt catacaagag gtagatagaa aagggaagta agatgaacta ttcaaaagca
    14821 ttgaatgaat gtatcgaaag tgcctacatg gttgctggac attttggagc tcgttatcta
    14881 gagtcgtggc acttgttgat tgccatgtct aatcacagtt atagtgtagc aggggcaact
    14941 ttaaatgatt atccgtatga gatggaccgt ttagaagagg tggctttgga actgactgaa
    15001 acggactata gccaggatga aacctttacg gaattgccgt tctcccgtcg tttgcaggtt
    15061 ctttttgacg aagcagagta tgtagcgtca gtggtccatg ctaaggtgct agggacagag
    15121 cacgtcctct atgcgatttt gcatgatggc aatgccttgg caactcgtat cttggagagg
    15181 gctggttttt cttatgaaga caagaaagat caggtcaaga ttgctgctct tcgtcgaaat
    15241 ttagaagaac gggcaggctg gactcgtgaa gatctcaagg ctttacgcca acgccatcgt
    15301 acagtagctg acaagcaaaa ttctatggcc catatgatgg gcatgccgca gactcctagt
    15361 ggtggtctcg aggactatac gcatgatttg acagagcaag cgcgttctgg caagttagaa
    15421 ccagtcatcg gtcgggacaa ggaaatctca cgtatgattc aaatcttgag ccgtaagact
    15481 aagaacaacc ctgtcttggt tggggatgct ggtgtcggga aaacagctct ggcgcttggt
    15541 cttgcccagc gtattgccag tggtgacgtg cctgcggaaa tggctaagat gcgcgtgtta
    15601 gaacttgatt tgatgaatgt cgttgcaggg acacgcttcc gtggtgactt tgaagaacgc
    15661 atgaataata tcatcaagga tattgaagaa gatggccaag tcatcctctt tatcgatgaa
    15721 ctccacacca tcatgggttc tggtagcggg attgattcga ctctggatgc ggccaatatc
    15781 ttgaaaccag ccttggcgcg tggaactttg agaacggttg gtgccaccac tcaggaagaa
    15841 tatcaaaaac atatcgaaaa agatgcggca ctttctcgtc gtttcgctaa agtgacgatt
    15901 gaagaaccaa gtgtggcaga tagtatgact attttacaag gtttgaaggc gacttatgag
    15961 aaacatcacc gtgtacaaat cacagatgaa gcggttgaaa cagcggttaa gatggctcat
    16021 cgttatttaa ccagtcgtca cttgccagac tctgctatcg acctcttgga cgaagcagca
    16081 gcaacagtgc aaaataaggc aaatcatgta aaagcagacg attcagattt gagtccagct
    16141 gacaaggccc tgatggatgg caagtggaaa caggcagccc agctaatcgc aaaagaagag
    16201 gaagtacctg tctacaaaga cttggtgaca gagtctgata ttttgaccac cttgagtcgc
    16261 ttgtcaggaa tcccagttca aaaactgact caaacggatg ctaagaagta tttaaatctt
    16321 gaagcagaac tccataaacg tgtcatcggt caagatcaag ctgtttcaag tattagtcgt
    16381 gccattcgcc gtaatcagtc aggaattcgc agtcataagc gtccgattgg ttcctttatg
    16441 ttcctaggac ctacaggtgt cgggaaaact gaattagcca aggctctggc agaagttctt
    16501 tttgacgacg aatcagccct tatccgcttt gatatgagtg agtatatgga gaaatttgca
    16561 gctagtcgtc tcaacggagc tcctccaggc tatgtaggat atgaagaagg tggggagttg
    16621 acagagaagg ttcgcaataa accctattcc gttctcctct ttgatgaggt agagaaggcc
    16681 cacccagata tctttaatgt tctcttgcag gttctggatg acggtgtctt gacagatagc
    16741 aagggacgca aggtcgattt ttcaaatacc attatcatta tgacatcgaa tctaggtgcg
    16801 actgcccttc gtgatgataa gactgttggt tttggggcta aggatattcg ttttgaccag
    16861 gaaaatatgg aaaaacgcat gtttgaagaa ctgaaaaaag cttatagacc ggaattcatc
    16921 aaccgtattg atgagaaggt ggtcttccat agcctatcta gtgaccatat gcaggaagtg
    16981 gtgaagatta tggtcaagcc tttagtggca agtttggctg aaaaaggcat tgacttgaaa
    17041 ttacaagctt cagctctgaa attgttagca aatcaaggat atgacccaga gatgggagct
    17101 cgcccacttc gcagaaccct gcaaacagaa gtggaggaca agttggcaga acttcttctt
    17161 aagggagatt tagtggcagg cagcacactt aagattggtg tcaaagcagg ccagttaaaa
    17221 tttgatattg cataaaagaa taaaagtatc agcatctgac cataagtcac agtggagtga
    17281 aactcaatga aaatcaaaga gcaaactagg cagctagccg caggttgctc aaaacactgg
    17341 tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt atgaaactaa
    17401 aacctatagc ttctaaacga tccgtggttt tcaccattca acacaaaatt catatgttta
    17461 ttaccctccg tcgtatttgt cttagagcgt gtgtagtaga aaaagagcag tcttatctga
    17521 aatttttatt ctttcaaaag agacctgttt cttttttgca tgtcaaatcc gttctagctg
    17581 gtatttgaaa aatcaaacta atattcaata aaaatcaaag aacaaactag gaagctagcc
    17641 gcaggttgct caaaacactg ttttgaggtt gtagatagag ctgacgtagt ttgaagagat
    17701 tttcgaagag tataagctgc aagatgaatg attttcttgt attgacgttg ttgttgacaa
    17761 aaagtagcgg ataaatgaaa tccattccat tatcatagat gataggctgg taggaaattt
    17821 tcaaatagca tacaggaaat agatgtatgg agttctggta gtagaaaggg agagagatga
    17881 acattttagt tgcagatgac gaggaaatga ttagagaagg aattgcagca tttctgacag
    17941 aagagggtta tcatgtcatt atggctaagg atggacaaga ggtcttggaa aaatttcaag
    18001 atctccctat ccatctcatg atattggatt taatgatgcc taggaagagt ggttttgaag
    18061 tgttaaaaga aatcaatcaa aagcacgata ttcctgtcat cgtcttgagt gctctgggag
    18121 atgaaactac tcagtcacag gtatttgatc tctatgctga tgatcatgtg acaaaacctt
    18181 tttctttggt actgcttgtc aagcgtatta aggcgcttat cagacgttac tacgtcatag
    18241 aggatatttg gcgatatcag gatgtaacag tggattttac ctcttacaaa gcacattata
    18301 aaaatgaaga aattgatctc aaaccaaagg aattactggt actaaagtgt ttgattcagc
    18361 ataaaaatca agttttaagt agagagcaga tattggaaga aatttcaaaa gatgtagctg
    18421 atttaccttg tgatagggtc gttgatgtct atattcgtac tcttcgcaaa aaattagctt
    18481 tagattgtat cgtgactgtg aaaaatgttg gatataagat tagcttatga taaaaaatcc
    18541 taaattatta accaagtctt ttttaagaag ttttgcaatt ctaggtggtg ttggtctagt
    18601 cattcatata gctatttatt tgacctttcc tttttattat attcaactgg agggggaaaa
    18661 gtttaatgag agcgcaagag tgtttacgga gtatttaaag actaagacat ctgatgaaat
    18721 tccaagctta ctccagtctt attcaaagtc cttgaccata tctgctcacc ttaaaagaga
    18781 tattgtagat aagcggctcc ctcttgtgca tgacttggat attaaagatg gaaagctatc
    18841 aaattatatc gtgatgttag atatgtctgt tagtacagca gatggtaaac aggtaacagt
    18901 gcaatttgtt cacggggtgg atgtctacaa agaagcaaag aatattttgc ttttgtatct
    18961 cccatataca tttttggtta caattgcttt ttcctttgtt ttttcttatt tttatactaa
    19021 acgcttgctc aatcctcttt tttacatttc agaagtgact agtaaaatgc aagatttgga
    19081 tgacaatatt cgttttgatg aaagtaggaa agatgaagtt ggtgaagttg gaaaacagat
    19141 taatggtatg tatgagcact tgttgaaggt tattcatgag ttggaaagtc gtaatgagca
    19201 aattgtaaaa ttgcaaaatc aaaaggtttc ctttgtccgc ggagcatcac atgagttgaa
    19261 aaccccttta gccagtctta gaattatcct agagaatatg cagcataata ttggagatta
    19321 caaagatcat ccaaaatata ttgcaaagag tataaataag attgaccaga tgagccactt
    19381 attggaagaa gtactggagt cttctaaatt ccaagagtgg acagagtgtc gtgagacctt
    19441 gactgttaag ccagttttag tagatatttt atcacgttat caagaattag ctcattcaat
    19501 aggtgttaca attgaaaatc aattgacaga tgctaccagg gtcgtcatga gtcttagggc
    19561 attggataag gttttgacaa acctgattag taatgcaatt aaatattcag ataaaaatgg
    19621 gcgcgtaatc atatccgagc aagatggcta tctctctatc aaaaatacat gtgcgcctct
    19681 aagtgaccaa gaactagaac atttatttga tatattctat cattctcaaa tcgtgacaga
    19741 taaggatgaa agttccggtt tgggtcttta cattgtgaat aatattttag aaagctatca
    19801 aatggattat agttttctcc cttatgaaca cggtatggaa tttaagatta gcttgtagac
    19861 agattagttt tttattaaag ttcatatagg gttaacataa gtgtgttatt ctttgtatag
    19921 ataaaagaaa ggatactaat atggtattag cgattatttt agtaacattc tttattcgat
    19981 tgattttttt aaagcgttcg atagagaatg agaaacgaat ccttagcaat ggcgggaaag
    20041 aatttggagt tgagaataca aaacgattaa ctatggctca tattgttttt tatctctctt
    20101 gcttggttga ggcaatggtg cacaagacaa tttttgatgg catgggtatg gttggtttag
    20161 tcttgcttat tttttctatg ctgatgttaa tgttggtgat tcacttgttg ggagatattt
    20221 ggacagtgaa gcttatgctt gtcaataatc acaaatatgt agatcatatc ttgtttagga
    20281 cagtaaaaca tcctaattac tttttaaata ttcttcctga gttgattggc ttgaccttgt
    20341 tgagtcatgc ttatgtgact tttgttttag tttttccagt ttatgcagtt attttgtatc
    20401 gacgaatagc tgaagaggaa aagctattac atgaagttat aatcccaaat ggaagcataa
    20461 agagataaat acaaaattcg atttatatac agttcatatt gaagtgatat agtaaggtta
    20521 aagaaaaaat atagaaggaa ataaacatgt ttgcatcaaa aaacgaaaga aaagtacatt
    20581 attcaattcg taaatttagt attggagtag ctagtgtagc tgttgccagt ctttttatgg
    20641 gaagtgtggt tcatgcgaca gagaacgagg gaactaccca agtagccact tcttctaata
    20701 aggcaaataa aagtcagaca gaacatatga aagctgctaa acaagtcgat gaatatataa
    20761 aaaaaatgct ccaattagat agaagaaaac atacccaaaa tgtcggctta ctcacaaagt
    20821 tgggcgcaat taaaacggag tatttgcatg gattaagtgt ttcaaaagag aagtcggaag
    20881 ctgagttgcc gtcaaaaata aaagcagagt tagacgcagc ttttgagaac tttaaaaaag
    20941 atacattgaa accaggagaa aaggtagcag aagctaagaa gaaggttgaa gaagcggagc
    21001 ttgaactagt aaaagaggaa gctaaggaac ctcgagacga ggaaaaaatt aagcaagcaa
    21061 aagagaaagt tgagagtaaa aaagctgagg ctacaaggct agaaaacatc aagacagatc
    21121 gtaaaaaagc agaagaagaa gctaaacgaa aagcagatgc taagttgaag gaagctaatg
    21181 tagcgacttc agatcaaggt aacccaaagg ggcggggaaa acgaggagtt cctggagagc
    21241 tagcaacacc tgataaaaaa gaaaatgatg cgaagtcttc agattctagc gtaggtgaag
    21301 aaactcttcc aagctcatcc ctgaaatcag gaaaaaaggt aacagaagct gagaagaagg
    21361 ttgaagaagc tgagaaaaaa gccaaggatc aaaaagaaga agatcgccgt aactacccaa
    21421 ccaatactta caaaacgctt gaccttgaaa ttgctgagtc cgatgtgaaa gttaaagaag
    21481 cggagcttga actagtaaaa gaggaagcta aggaacctcg agacgaggaa aaaattaagc
    21541 aagcaaaaga gaaagttgag agtaaaaaag ctgaggctac aaggttagaa aaaatcaaga
    21601 cagatcgtaa aaaagcagaa gaagctaaac gaaaagcagc agaagaagat aaagttaaag
    21661 aaaaaccagc tgaacaacca caaccagcgc cggctcctca accagaaaaa ccagctccaa
    21721 aaccagagaa gccagctgaa caaccaaaag cagaaaaaac agatgatcaa caagctgaag
    21781 aagactatgc tcgtagatca gaagaagaat ataatcgctt gactcaacag caaccgccaa
    21841 aaactgaaaa accagcacaa ccatctactc caaaaacagg ctggaaacaa gaaaacggta
    21901 tgtggtactt ctacaatact gatggttcaa tggcaacagg atggctccaa aacaacggtt
    21961 catggtacta cctcaacagc aatggtgcta tggcaacagg ttggctccaa aacaatggat
    22021 catggtatta cctaaatgct aacggtgcta tggcaacagg atggctccaa aacaatggat
    22081 catggtacta cctcaacagc aatggcgcta tggcgacagg atggctccaa tacaatggtt
    22141 catggtacta tctcaacgct aatggtgata tggcgacagg atggctccaa aacaacggtt
    22201 catggtacta cctaaacgct aacggtgcta tggcaacagg ttgggctaaa gtcaacagtt
    22261 catggtatta cctcaacgct aacggtgcta tggcaacagg ttgggctaaa gtcaacagtt
    22321 catggtatta cctaaacgct aatggtgata tggcgacagg ttgggtgaaa gatggagata
    22381 cctggtacta tcttgaagca tcaggtgcta tgaaagcaag ccaatggttc aaagtatcag
    22441 ataaatggta ctatgtcaat ggctcaggtg cccttgcagt caacacaact gtagatggct
    22501 atggagtcaa tgccaatggt gaatgggtaa actaaaccta atataactag ttaatactga
    22561 cttcctgtaa gaacttttta aagtattccc tacaaatacc atatcctttc agtagataat
    22621 atacccttgt aggaagttta gattaaaaaa taactctgta atctctagcc ggatttatag
    22681 cgctagagac tacggagttt ttttgatgag gaaagaatgg cggcattcaa gagactcttt
    22741 aagagagtta cgggttttaa actattaagc cttctccaat tgcaagaggg cttcaatctc
    22801 tgctagggtg ctagcttgcg aaatggctcc acggagtttg gcagcgccag atgttccacg
    22861 gagatagtga ggagcgaggc cgcggaattc acgaactgcg acgttttctc ctttgaggtt
    22921 aatcaatcgt ttcaagtgtt cgtaggcgat cttcatcttg tcttcaaagg tcaaatcagg
    22981 taggatttct cctgtttcaa agtaatggtt gatttggttg aagaggtaag gatttcccat
    23041 ggcagctcgg ccaatcatga ctgcgtcagc accaacttct tcgatgcgtt gcttggcttc
    23101 ttggacagta cggatatcac cgttggcgat gaatggaatc ttggttagag cttgggcaac
    23161 cttgtaaagg gtctcaaggt ctgcgtggcc agtatacatt tgttcacggg tacggccatg
    23221 catggcgagg gcagaaacac ctgcagcctc agcagcgagg gcattttcta ctgccagaga
    23281 tgggtccgcc cagccggtac gcattttgac agtaagtggg atatcaagga cagactggac
    23341 cttgttgatg atagagtaga tcttgtcagg atccttgagc cacatagctc cagcttcgtt
    23401 cttcacgatt ttgttgacag ggcagcccat gttgatatcg acgatatcgg tcttggtgtt
    23461 ttcttggatg aattctgctg cgcgtgctag gctgtcttca tcgctaccaa aaagttggat
    23521 agagacaggg ttttcgccct catcgatatg aagcatgtgc agggtttttt cgttgttgta
    23581 ttggattccc ttgtcagaga ccatttccat tacaacgagt ccagctccga gctcttttgc
    23641 gatggtacga aaggctgagt tggtcacgcc agccataggc gctaaaacgg tacgattggg
    23701 aatctcaata ttgccaatca taaaaggtgt attaagattt gtcacgaatg agttcctcca
    23761 ggtccttttc atcaaagttg taagtagttt ggcagaattg acaagtgatt tctgccccgt
    23821 ggtcttcctc tttcatttcc tgtaagtctg agcttggaag gctggcaaga gcgttcataa
    23881 agcgttcatg gctacagtca cattggaaac ggatttcttc ttcagaaaga cgcttgtagg
    23941 cttcgtcccc gtagatagcc ttgaggaggg cttcgatatg gtcgtcgctt tcgagaagag
    24001 tagagatagc tggcatttct tggatgcgtt tttcaaagcg agcaatctct tctttcttgg
    24061 ctcctggcaa gacttgaact aggaaaccac ctgcaacctt gaccttgtct tcctcgtcca
    24121 aaaggacatt gaggccgacc gctgaaggcg tttgttggct ttcagtaagg taaaaggcaa
    24181 ggtcttcacc gatttctcca gagatgaggg gagttataga gttgtaagga tttccagtac
    24241 cgtagtctgt gataacgagg aattgaccat ttccaacaaa aggtccgact aggacttcac
    24301 cagtcgcagt ctttttgatg tcaacaccag gattttgaac atagcctttg acgttcccct
    24361 tggtatcagc gacggtgata atagcaccta gagagctaga tcccaacacc ttaactgtaa
    24421 gtttggtatt tcctttttca ttggctgcga gaatctggct ggcgataaga gttcgaccaa
    24481 gcgctacagt tgagctagct tgggtttgat gtttttcttg agcagtgcgg acggtttcag
    24541 tgctatcaag gacaaaagca cgaaaggctc cgctttctga tatagtttta ataattttat
    24601 ccatagctac tattttagca taaaaatgcc caaaggggga gccgtgtgtt tactgatttt
    24661 caggataatg gaccaggaaa tcagcatgaa aataaaaaga gaaacagatt atttcagcat
    24721 ttgtaagatt tatgctatgc ttaaggtaga aaatgaaagg ggtaacaaat gtatttagga
    24781 gatttgatgg agaaagccga gtgtggtcaa ttttcaatcc tttcctttct attacaagag
    24841 tctcagacga ccgtcaaggc tgtaatggaa gaaacaggat tttcaaaagc aaccctaacc
    24901 aaatatgtca ccctgctcaa tgacaaggct ttggatagtg gcttagagct ggctattcac
    24961 tcagaagatg aaaatctgcg tctgtctatc ggtgcagcta ccaaggggag agatattcgg
    25021 aacttgtttt tggatagtgc tgttaaatac cagattttgg tttatcttct ctaccaccaa
    25081 cagtttttag cccatcagct ggctcaagaa ttggtgatta gcgaggctac gcttggtcgt
    25141 cacttggctg gtttaaatca gattttgtca gaatttgatt tatccatcca aaatggacgt
    25201 tggcgaggtc cagagcatca gattcgctat ttctatttct gtcttttccg aaaggtctgg
    25261 tcgagtcagg aatgggaagg tcacatgcag aaaccagaga gaaaacagga gattgccaat
    25321 ttagaggaaa tctgcggtgc aagtttgtct gccgggcaga aattggactt ggttctctgg
    25381 gctcacatca gtcaacaacg tcttcgggtc aatgcttgtc agtttcaagt catagaagag
    25441 aaaatgcgag ggtattttga caatatcttt tatcttcgtt tgctgagaaa ggttccgtcc
    25501 ttttttgctg ggcaacatat tccactagga gttgaggatg gtgagatgat gatattcttc
    25561 tcttttctcc tatctcatcg cattcttcct cttcatacta tggagtatat tcttggtttt
    25621 ggagggcagt tggtagattt actgacgcaa ttgattcaag aaatgaagaa ggaggaacta
    25681 ttgggggatt atacagaaga ccatgtcacc tatgaactca gtcagctttg tgctcaagtc
    25741 tatctctata agggctatat tttacaggac cgttacaagt accagttaga gaatcgtcat
    25801 ccatatttac tgatggaaca tgattttaaa gagacagcag aggagatttt tcatgctcta
    25861 cctgcttttc aacaggggac agatttagat aagaagattc tctgggaatg gctccagtta
    25921 atcgaatata tggctgaaaa cggtggtcag catatgcgga ttggtctgga tttgacatct
    25981 ggttttcttg tcttttcaag gatggcagcc attttgaaac ggtatttgga atacaatcgt
    26041 tttattacca ttgaagctta tgaccctagt cggcattatg atttgctggt taccaataac
    26101 ccgattcata agaaggaaca gacaccagtc tattatttaa aaaatgactt ggatatggag
    26161 gatttggtag cgattcgcca gttattattc acttaaaagg cttggttaat ccaggtcttt
    26221 tttgtgaaat tcacacaatc tcctcgcatt tttttaaaaa ttaaaaaaag ttgataaaca
    26281 agaaagcgct ttattttgta tactagtaag tgtaaagagg aaacacctca agatctttat
    26341 caggaggaca gtacatgtca caagaaaaat acatcatggc cattgaccag ggaactacaa
    26401 gttctcgtgc catcattttc aacaaaaaag gggaaaaggt tagctcgagt caaaaagagt
    26461 ttacccagat tttccctcaa gcaggttggg ttgagcacaa tgccaatgaa atttggaact
    26521 ctgttcagtc agttattgcg ggtgctttca tcgaaagtgg tgtcaagcca aatcaaatcg
    26581 aggcaatcgg gattaccaac caacgtgaaa caacggttgt ctgggataag aaaacaggac
    26641 ttcctatcta caatgctatc gtttggcagt cacgccagac agcacctttg gctgagcaac
    26701 taaaaagcca aggttatgtg gaaaaattcc atgaaaagac tggtttgatt attgatgctt
    26761 acttctctgc taccaaggtt cgttggattt tggatcatgt agaaggtgct caagagcgag
    26821 cagaaaaagg ggaattgctc tttggtacta tcgatacttg gttggtttgg aaattgactg
    26881 acggtgcggc tcacgtgact gactactcaa atgcagctcg taccatgctt tataacatta
    26941 aagaactcaa atgggatgat gagattttgg aaatccttaa cattccgaag gctatacttc
    27001 cagaagttcg ttctaactcc gaaatctacg gcaagacagc tccattccat ttctacggtg
    27061 gagaggtgcc aatctcaggt atggctgggg accaacaagc agccctcttt ggacagttgg
    27121 cttttgagcc aggtatggtt aagaatactt atggaacagg ctctttcatc atcatgaata
    27181 ctggggaaga gatgcagttg tctgaaaaca acctcttgac aaccattggt tacggaatca
    27241 acggtaaggt ttattatgcc ttggaaggtt ctatcttcat cgcaggaagt gctattcagt
    27301 ggcttcgtga cggtcttcgc atggttgaaa attcaccaga atctgaaaaa tacgctcgtg
    27361 attctcacaa caacgatgaa gtttatgtcg ttccagcctt tacaggtcta ggcgctccat
    27421 actggaacca aaatgctcgt ggttccgtct ttggtttgac tcgtggaaca agcaaagaag
    27481 actttatcaa ggcgactttg caatcgattg cttatcaagt gcgtgacatc atcgacacca
    27541 tgcaagtgga tactcagacc accattcaag tactgaaggt ggatggtggt gcagccatga
    27601 acaacttcct catgcagttc caggcggata ttttaggcat tgatattgca cgtgctaaaa
    27661 acttggaaac aacagctcta ggagcggcct tcctagcagg tttgtcagta gggtactgga
    27721 aagacttgga cgagttgaaa ctcttgaacg agacaggaga actctttgag ccatctatga
    27781 acgaatctcg caaggaacaa ctctacaagg gttggaagaa ggctgtgaaa gcaactcaag
    27841 tctttgcgga agtagacgac taatactggc agaataaagc gatttattta gaaagtgtgt
    27901 aaatatggaa ttttcaaaga aaacacgtga attgtcaatt aaaaaaatgc aggaacgcac
    27961 cctggacctc ttgattatcg gtggaggaat cacaggagct ggtgtagcct tgcaggcggc
    28021 agctagcggt cttgagactg gtttgattga aatgcaagac tttgcagaag gaacatctag
    28081 tcgttcaaca aaattggttc acggaggtct tcgctacctc aaacaatttg acgtagaagt
    28141 ggtctcagat acggtttctg aacgtgcagt ggttcaacaa atcgctccac acattccaaa
    28201 atcagatcca atgctcttac cagtttacga tgaagatgga gcaaccttta gcctcttccg
    28261 tcttaaagta gccatggact tgtacgacct cttggcaggt gttagcaaca caccaactgc
    28321 gaacaaggtt ttgagcaagg atcaagtctt ggaacgccag ccaaacttga agaaggaagg
    28381 cttggtagga ggtggagtgt atcttgactt ccgtaacaac gatgcgcgtc tcgtgattga
    28441 aaacatcaaa cgtgccaacc aagacggtgc cctcattgcc aaccacgtga aggcagaagg
    28501 cttccttttt gacgaaagtg gcaagattac aggtgttgta gctcgtgatc tcttgacaga
    28561 ccaagtattt gaaatcaagg cccgtctggt tattaataca acaggtcctt ggagtgataa
    28621 agtacgtaat ttgtctaata agggaacgca attctcacaa atgcgcccaa ctaagggagt
    28681 tcacttggta gtagattcaa gcaaaatcaa ggtttcacag ccagtttact ttgacacagg
    28741 tttgggtgac ggtcgtatgg tctttgttct cccacgtgaa aacaagactt actttggtac
    28801 aactgataca gactacacag gtgatttgga gcatccaaaa gtaactcaag aagatgtaga
    28861 ttatctactt ggcattgtca acaaccgctt tccagaatcc aacatcacca ttgatgatat
    28921 cgaaagcagc tgggcaggtc ttcgtccatt gattgcaggg aacagtgcct ctgactataa
    28981 tggtggaaat aacggtacca tcagtgatga aagctttgac aacttgattg cgactgttga
    29041 atcttatctc tccaaagaaa aaacacgtga agatgttgag tctgctgtca gcaagcttga
    29101 aagtagcaca tctgagaaat atttggatcc atctgcagtt tctcgtgggt ctagcttgga
    29161 ccgtgatgac aatggtcttt tgactcttgc tggcggtaaa atcacagact accgtaagat
    29221 ggctgaagga gctatggagc gcgtggttga catcctcaaa gcagaatttg accgtagctt
    29281 taaattgatc aattctaaaa cttaccctgt ttcaggtgga gaattgaacc cagcaaatgt
    29341 ggattcagaa atcgaagcct ttgcgcaact tggagtatca cgtggtttgg atagcaagga
    29401 agctcactat ctggcaaatc tttacggttc aaatgcaccg aaagtctttg cacttgctca
    29461 cagcttggaa caagcgccag gactcagctt ggcagatact ttgtcccttc actatgcaat
    29521 gcgcaacgag ttggctctta gcccagttga cttccttctt cgtcgtacca accatatgct
    29581 ctttatgcgt gatagcttgg atagcatcgt tgagccagtt ttggatgaaa tgggacgatt
    29641 ctatgactgg acagaagaag aaaaagcaac ttaccgtgct gatgtcgaag cagctctcgc
    29701 taacaacgat ttagcagaat taaaaaatta agaaaaaata aaagaggtgg agggcagcat
    29761 tccttgtcgc tcgtcccttc tttttaatgg agacagaaag atgatgaatg aattatttgg
    29821 agaatttcta gggactttaa tcctgattct tctaggaaat ggtgttgttg caggtgtggt
    29881 tcttcctaaa accaagagca atagctcagg ttggattgtg attactatgg gttgggggat
    29941 tgcagttgcg gttgcagtat ttgtatctgg caagctcagt ccagctcatt taaatccagc
    30001 tgtgacaatt ggtgtagctt taaaaggtga cttgccttgg gcttccgttt tgccttatat
    30061 cttagcccag ttcgcagggg ctatgctggg tcagattttg gtttggttgc aattcaaacc
    30121 tcactatgag gcagaagaaa atgcaggcaa tatcctggca accttcagta ctggaccagc
    30181 catcaaggat actgtatcaa acttgattag cgaaatcctt ggaacctttg ttttggtgtt
    30241 gacaatcttt gctttgggtc tttacgattt tcaggcaggt atcggaacct ttgcagtggg
    30301 taccttgatt gtcggtatcg gtctatcgct aggtgggaca acaggttatg ccttgaaccc
    30361 agctcgtgac cttggacctc gtatcatgca cagcatcttg ccaattccaa acaagggaga
    30421 cggagactgg tcttacgctt ggattcctgt tgtaggccct gttatcggag cagccttggc
    30481 agtgcttgta ttctcacttt tctagtttat actcttcgaa aatcaaattc aaaccacgtc
    30541 agcgtcgcct taccgtactc aagtacagct tgcggctatc ttcctagttt gctctttgat
    30601 tttcattgag tattagaaaa caattatgtt gatagagctt gggcaagagc ccaatttcag
    30661 caaaaaatga agtaaatctt ctcataataa aacgcatcat atcaagcacg aaaattccac
    30721 gaggtcaact acagtcagaa agctgaacaa caagccaaaa cgcccaaaaa aggcggcaaa
    30781 aagcaagcac ctgcaagcaa cgtgccgaaa tggtcaaatc ctgattatgt caacgaatta
    30841 gacccaaaaa tcgttgatat gctagtagaa tttcacaagt cacaaggcac tttggaaact
    30901 cccgaggcgc aagcagaaat cgcccaaaaa cgtgaagaaa tcgagcaaag gagagctgag
    30961 cttgaggata aaaaacaaga gcttttgaac cgcttgaaca aatagagttt cgcaagtatt
    31021 atgcttacaa attacttgag caattaacta aaatataaac cctgccttta tatctaggca
    31081 gggtttatat tttagaaatt cacgtaggtt gttacggttt ttacataccc agtatagttt
    31141 gagtttctat agtattcagt gataaacttc cattttcttt gaacaacatg gatataagta
    31201 cttgttatgt agtatggata tgggctttgt gaatccaagt aagactgata agcttgtata
    31261 ccaaaatatg ctccaccaat tattgcaccc catggacccc ccaataaagc acctatccta
    31321 ccaatcatat aactgattcc agcaccagtc atgaagttag cgaatgtgtt agcttgttta
    31381 ttcccatgta ttgtgttgac gtaattccaa acattaggat cgtatgatct aaaagatata
    31441 tttaggtcga tttcattctt ttgataagcc atataaaatg ccccattgat atagacgccg
    31501 tcagcacgtc gttcaatagt gtctacactt ccatctggat tgacaacctc aagaacttca
    31561 tcgcttaaaa tatttacttg cgtatctccg aaccgcactg atgagccatt ctcaaactga
    31621 gcctcaccag atctttagag tttgccgata agctatcatc agcaaaaaca acaagcgacg
    31681 gggaaatgct agacatacag aaaacagaca taactagcaa acacatgcat ttaaacatct
    31741 tagacataac ggaaactcct ttgtattttt gatttttttc aacttttatt atacaataaa
    31801 accaaataaa aagaaagcgg taacaatatg cttaatgcga aaatttttta tatattttta
    31861 tgtttgatcg ttatcgaaac tacaggcttg ttgttgttga aaagaggtct cgaaatgggt
    31921 tatttagaca cagaagctat tatcctcgca gttttttcat ttgcttttta caacctatgt
    31981 tcattcgctt gggtctgctc tacaataaaa aataaataga cgtattttca aaaaaaaaaa
    32041 aatgcatatt tatcttagca aaacgacgat ttaaatcgtc gtttttttgt agtacgacgg
    32101 gcatgtcgta tatctgaggt gtaagtcctc ggtgggcacc tgctaccggt gaacccaata
    32161 gcgattccca agcctgacta tcgtgaggta gcagggagag gaagggatag cgaaatcgtg
    32221 gctctacgaa caggaacgtg atagtaaggc gtatatagcg gataaggagg cttcaaactc
    32281 taaagtccaa aaaggtagtc gtaacctata tgtgtaaatc acgagagtaa ttgaattcgg
    32341 actaaggttt gtgtgaaaaa gataaatctt tctagagtct aaagactctg cgtcagattt
    32401 cctattttca ctgtaacctt ttaacgtcct catatcttgt ataaacgagg aaagatgtac
    32461 gacttatccc gtgaggtttc atgagcgctg aaagcgtagt aacaacgaat catgagaagt
    32521 cagccgagcc catagtagtg aggaaacttc tgtagtggaa gtggagcgaa ggggtgaata
    32581 ctcaaacagt ctggggagag actgtttgag gtctgtcgct agaaagagaa aacgacagat
    32641 cgaagtaatc ctacttcact tgtgtctgta aaatgagtgg tctgatagaa ctggactttg
    32701 acacgtaatg actagatgaa ggttcaccaa tataagatgt ccctcaggca ccaaaacaag
    32761 aaaggaatac gcacatgtca aaactgctag ataagatatt atcacgcgaa aatatgctgg
    32821 aagcctacaa tcaagtaaaa tccaataaag gctcagctgg gattgatgga atgactatcg
    32881 aagagatgga taattatctc agacaaaact ggcgcttgac taaggaactg ataaaacaga
    32941 gaaaatataa gcctcaacca gttcttaaag ttgagatacc taaaccagac ggaggcatcc
    33001 gtcaactagg aattccaaca gttatggata gaatgattca acaggccatt gtccaagtca
    33061 tgagccccat ttgtgaaccc catttctcag atacgagtta tggtttcaga ccaaataggt
    33121 catgtgaaaa agccatcatg aagctcttag aatacttaaa tgacggctat gagtggatag
    33181 tggatataga cctagagaaa tttttcgata cagttcctca agatagattg atgtccttag
    33241 tacataacat tatcgaagac ggagatacgg aatccttgat tcgtaagtat cttcattcag
    33301 gtgttatcat taatggtcaa cgttataaaa cactagttgg tacaccacag ggaggaaatt
    33361 tatctcctct cttatccaat atcatgctta atgaattgga caaggaatta gaaaagaggg
    33421 gacttcgatt tgtgcgctac gcagatgatt gtgtgattac ggtcggaagc gaggcagcct
    33481 ctaagcgtgt gatgtattca gtcagtcgtt ttattgagaa acggctaggt ttgaaagtaa
    33541 acatgaccaa gactaagatt accagaccaa gagagttgaa atatctaggt tttgggttct
    33601 ggaaatcatc agatggttgg aaaagccgtc cacatcaaga tagtgttcgg agatttaagt
    33661 ttaaattgaa gaaactaaca cagaggaaat ggagtataga cctaacaaga cgtattgagc
    33721 aactgaattt gtctattcga ggatggataa actatttctc attgggaaat atgaaaagta
    33781 tagtcgccag catagatgag cgcttgcgta ctcgcctacg agtgattatc tggaagcaat
    33841 ggaagaagaa atcgagacga ttatggggat tgcttaagtt aggagttcct aaatggatag
    33901 cagataaggt atctggctgg ggcgaccatt atcaattagt agctcagaag tcggtactta
    33961 aacgtgctat atcaaaacca gtcctggaaa aacgtggact ggtttcgtgt ttggattatt
    34021 accttgaacg acatgcgtta aaagttagtt gaaccgccgt atgccgaacg gcacgtacgg
    34081 tggtgtgaga ggggctagag attatcccct actcgattaa ctcccctgaa atttatttta
    34141 attatgcaaa tttcacgtat ttttgatgct gagacgacga tcctgggaac ttttcagata
    34201 tttttttgac tatctaaatc tatcattaga aaagcttaga gcgccaaagg atttgagcgt
    34261 ttttctgatt tttaagactt tttccagtct ctttttcgat tgaagatgta attattctac
    34321 taactaacta acttcttagt actagccaac aacgataatc ataattcctc ctaaaattag
    34381 gaataataaa ggcaatagtt tttgtttttt catgtaaaaa acctcacttt tgttttctgc
    34441 tattttatgc taaaatatta aaaatcaaat ttaattccaa agtttgtaac taaaggggga
    34501 gcgctacatg tctaattcat ttgtcaagtt gttagtctct caattatttg caaatttagc
    34561 agatattttc tttagagtaa caatcattgc taacatatac attatttcaa aatcagtaat
    34621 tgccacatca ctagttccta tcttaatagg aatatcctct tttgttgcga gtcttttagt
    34681 tccgttggtt actaaaaggt tagcgctaaa tagggtttta tctttatctc aatttggaaa
    34741 gactatatta ttggcgatac tggtaggaat gtttaccgta atgcaatccg tagcgccttt
    34801 ggtgacctat ctatttgttg ttgcaatttc catactagat ggttttgcag cacccgtttc
    34861 ctatgctatt gtgccacgct atgcgaccga tttgggtaag gctaattcag ccttatcaat
    34921 gactggtgaa gctgttcaat tgataggttg gggattaggt ggactcttgt ttgcaacaat
    34981 tggtctgtta cctaccacgt ttatcatttt agtcttgtat atcatttcta gctttctgat
    35041 gttatttctt cctaacgctg aagtggaggt gttagagtca gaaactaatc ttgaaatttt
    35101 gctcaaaggt tggaagttag ttgctagaaa tcctagatta agactttttg tatcagcaaa
    35161 tttattggaa attttttcaa atacgatttg ggtttcttcc attatacttg tttttgtaac
    35221 ggagttatta aataaaacgg aaagttactg gggatattct aatacagcat actctattgg
    35281 tattataatt agtggcttaa ttgcttttag gctatctgaa aagttccttg ctgctaaatg
    35341 ggaaagtatt ctttttcctc ttgtagctat ggcaatagtg acactgacta ttctatattt
    35401 tccaaacgca cagatgtttt tattattttc agctttagtt ggtatgttat cgcaactaaa
    35461 agaagttcct gaaagtgtat ttcttcagga aacagtagag gaaaatcatt tagttaatgt
    35521 ctattccgtt cttgaagtga tttctacatt agcattttca gtatttgttt tgctaatgag
    35581 ctatattact gagagttttg gtattagcat cagtttttgg ctatcagcca tttgtctgat
    35641 gatagaagct attttaattt atatcagacg agattatttt aaatgagaga gtggttaaaa
    35701 agtctttaaa aatcagaaaa gcgcatagta tcaggtgttg aaaaaacttg atattgtgtg
    35761 ttttattatg ggaagattta cttcattgtc tcctgaaatg gagttttgaa gcaggatcac
    35821 tctatttgaa aatatacata gaaaaaccgc ataatcctta aaataagctg aaatctattg
    35881 gaaacatacg gtaaacaatt gaaaagatac tatataaagt ggtacaatgg tagaaaaata
    35941 agctagtaag aatcactctt attttagcga attttagcga aaaattacag aaatgaatgg
    36001 tttttcttga tgaaacagag aaaagaattg tacctctttc ttggtcggac agccttgtat
    36061 tttcttatct ttctagggct gctttacttc tttagctatc ttggtcaggg tcaaggaagc
    36121 tttatctata atgaatttta acttgaagga gaatccctat tgtgtcaaat aaaccaatag
    36181 cagatatgat tgaaaccatt gagcattttg ctcagacaca gcctagctat cctgtctata
    36241 atgttttggg gcaggaacac acttatggcg atttaaagtc tgattcggat agtttggctg
    36301 cagtcattga ccaactaggc ttgcctgaga agtctcctgt ggttgttttt ggtggccaag
    36361 aatatgaaat gttggcaacc tttgtagcgc tgactaagtc aggtcatgcc tacattccaa
    36421 ttgatagcca ttcggccttg gagcgagttt cagctatttt agaagtagca gagccaagct
    36481 tgattattgc catttcagcc tttcccttgg agcaggtttc tacaccaatg ataaatctag
    36541 ctcaggttca agaagccttt gcccaaggga acaactatga aatcacgcat ccagtcaagg
    36601 gagatgataa ttactacatt atctttactt ctggtacgac tggtcagcct aagggagtgc
    36661 agatttcaca tgataatctc ctcagcttta caaactggat gattacggat aaggaatttg
    36721 cgacaccgag tcgtccgcaa atgctggcac agccacctta ttcttttgac ttgtctgtca
    36781 tgtattgggc accgaccttg gcacttggtg gtacgctttt cactcttcct tcagtcatca
    36841 ctcaggactt taagcaactc tttgcggcta tcttttcatt gccaatcgct atctggacat
    36901 caacaccatc ctttgcagat atggccatgt tgtctgaata cttcaacagt gagaaaatgc
    36961 ctggaatcac gcatttctac tttgatggtg aagaattgac ggtcaaaaca gctcaaaaac
    37021 tgcgcgagcg tttcccaaat gcccgtatca tcaatgctta cggcccaaca gaagcgacag
    37081 tagctctgtc agcagttgcc gtgacagacg agatgttagc gactctcaaa cgcctaccaa
    37141 tcggctatac caaggctgat tctccaacct ttatcattga cgaggaagga aataaactgc
    37201 caaatggtga gcagggagaa atcattgttt ctgggccagc tgtttcaaaa ggttatatga
    37261 acaatcctga aaaaacagca gaagccttct ttgagtttga agatctgcca gcctatcaca
    37321 caggcgatgt gggaaccatg acagatgagg gcttgcttct ctacggcgga cgcatggact
    37381 tccagattaa gtttaacggt taccgcattg agttagaaga tgtctctcaa aacctcaaca
    37441 agtctcgctt tatcgaatct gctgtcgcag taccgcgcta taacaaggac cacaaggtac
    37501 aaaatctatt ggcttatgtc atcttaaaag acagtgttcg tgagcagttt gagcgagata
    37561 tcgatattac caaggccatc aaggaagacc tgacagacat catgatgtcc tacatgatac
    37621 catctaaatt cctttaccga gacagtttgc cactgactcc aaatggaaag attgacatca
    37681 aaggattgat taacgaggtg aataagagat gatggagttt tttcaacagc ttcctcattt
    37741 agagccatat ggcaatcctc agtattttgt ttatgtgatt gctgcaacct tgcccatctt
    37801 tataggtctc tttttcaaga aacgctttgc ctggtatgaa gtgttggtaa gtctcttctt
    37861 tattgtcacc atgttggtgg gtggaaagac caatcaacta gctgccttgg gtatttacct
    37921 ttgctgggaa atattgctcc tgcttttcta caagcattat cgaaaaagca aggatggcaa
    37981 gtgggtcttc tacttagtta gttttctgtc cctacttccg attatctttg tcaaggtgca
    38041 accagctatc aatggaacgc agtctttgct tgggttcttg ggaatttctt acctgacctt
    38101 tcgttcggtt gggattatca tcgagctgag agatggagtg attaaggatt ttaccctctg
    38161 ggaattcctc cgtttccttc tcttcatgcc aactttctcg agtggtccaa tcgatcgctt
    38221 taagcgattt aatgaaaatt atcaggccat tcctgagcga gatgagttga tggatatgct
    38281 ggatgaatct gtccgctata tcatgcgggg ctttttgtat aagtttatcc tagctcatgt
    38341 tttaggagag accttactac ctcctctgaa gaatttagcc ttgcagtcag gtggcttctt
    38401 taatctctat gccttggcag ttatgtatac ttttggtctg gagctcttct ttgactttgc
    38461 aggttattct atgtttgctt tggccatctc aaacttgatg ggaatccgta gccctatcaa
    38521 ctttaacaag ccctttttat caagggattt aaaggagttt tggaatcgct ggcatatgag
    38581 tctgtccttc tggttccgtg actttgtctt tatgcgaatg gtgatggtgt taaccagaaa
    38641 gaaagtcttt aaaaatcgta atgtaacctc aagcatggcc tacattgtaa atatgctgat
    38701 tatgggattt tggcatggcg tgacctggta ctatatcgcc tatggactct ttcatggact
    38761 aggtttggtc atcaatgatg cctgggttcg caagaaaaaa acgctcaata aggaacggaa
    38821 aaaagcaggg aaggctgccc tacctgagaa tcgctggatt cagttgcttg gcatggttgt
    38881 cactttccat gttgtcatgt tgtcattctt aatcttttct ggattcttga ataatctatg
    38941 gtttaaaaaa taaaaggaaa taaaatatgg atatcaaatc agaagttatt gaaattattg
    39001 atgagttgtt tatggaagat gtttctgaca tgatggatga agatcttttt gatgcaggtg
    39061 tcttggatag tatgggaacg gttgagttga ttgtggagat tgagaaccgt tttgacattc
    39121 gtgtccctgt aacagagttt ggtcgtgacg actggaatac agctaataaa atcatagctg
    39181 gtattgtgga gctacaaaat gcttaaacgc ttatggatga tcttcggacc ggtcttgatc
    39241 gctggtttgt tggtttttct gctcattttc ttttatccta ctgagatgca tcataatcta
    39301 ggagctgaaa agcgttcagc agtggctact actatcgata gttttaagga gcgaagtcaa
    39361 aaagtcagag cactatctga tccaaatgtg cgttttgttc ccttctttgg ctctagtgaa
    39421 tggcttcgtt ttgacggtgc tcatcctgcg gtattagctg agaaatacaa tcgttcctac
    39481 cgtccttatc ttttaggaca ggggggagct gcatcgctta accaatattt tggaatgcaa
    39541 cagatgttac cacagctgga gaataaacaa gttgtgtatg ttatctcacc tcagtggttc
    39601 agtaaaaatg gctatgatcc agcagccttc cagcagtatt ttaatggaga ccagttgact
    39661 agttttctga aacatcaatc tggggatcag gctagtcaat atgcagcgac tcgcttactg
    39721 caacagttcc caaacgtagc tatgaaggac ctggttcaga agttggcaag taaaggagaa
    39781 ttgtcgacag cagacaatga aatgattgaa ttattggctc gttttaatga acgccaagcc
    39841 tccttttttg gtcagttttc ggttagaggc tatgttaact acgataagca tgtagctaag
    39901 tatttaaaaa tcttgccaga ccagttttct tatcaagcaa tagaagatgt tgtcaaagca
    39961 gatgctgaaa aaaatacttc caataatgag atgggaatgg aaaattattt ctataatgag
    40021 cagatcaaga aggatttgaa gaaattaaag gattctcaga aaagctttac ctatctcaag
    40081 tcgccagagt ataatgactt gcagttggtt ttaacacagt tttctaaatc taaggtaaac
    40141 ccgattttta tcattccacc tgttaataaa aaatggatgg actatgctgg tctacgagag
    40201 gatatgtacc aacaaacggt gcagaagatt cgctaccagt tagaaagtca aggttttacc
    40261 aatatagcag atttttctaa ggacggcggg gagcctttct ttatgaagga caccattcac
    40321 cttggttggt tgggttggtt ggcttttgac aaggcagttg atcctttcct atccaatccc
    40381 acaccagctc cgacttacca tctgaatgag cgctttttca gcaaagattg ggcgacttat
    40441 gatggagatg tcaaagaatt tcaatagata atataatata gaagagttca agaatgaaac
    40501 tagttttcac gttttttctt gactcttttt ttgcttgtga tataattaac tggtaaacaa
    40561 aatgtcaaag aatagtattt ttctcttaaa aaagagaagt ctaaaaggaa aggagtcaga
    40621 tatgagacag ctagcaaagg atatcaatgc ttttttgaat gaggtgattt tgcaggcgga
    40681 aaatcagcat gaaatcctaa taggtcattg cactagcgag gtggccctga ccaatactca
    40741 ggagcatatc cttatgctct tgtcagagga atctttaaca aattcagaat tggcccgtcg
    40801 tctcaatgtc agtcaggcgg cagttaccaa ggccattaag tctttggtca aggaagggat
    40861 gttggaaaca tctaaagatt ctaaagatgc gcgtgtgatt ttttatcagt tgactgactt
    40921 ggctcgtcca atcgctgagg agcaccacca tcaccatgag catacacttt taacctatga
    40981 acaagtggcg actcagttta ctccaaatga acaaaaagtg attcagcggt ttttgactgc
    41041 tttagtagga gaaatcaaat aatgagatat attacggtag aggatttgtc cttctattat
    41101 gataaggagc ctgttcttga acatatcaat tattgtgttg atagtgggga atttgttacc
    41161 ttgactgggg aaaatggagc ggctaagacg acgctcatca aggctagtct tggaattctg
    41221 caaccacgca ttggaaaggt ggctatttca aagacaaata cgcaaggtaa gaaattgaga
    41281 atagcctatc ttcctcaaca aattgccagt tttaatgctg gttttccaag tacggtctat
    41341 gaatttgtca agtcgggtcg ctatccgaga aaaggctggt tccgtcgttt gaatgctcat
    41401 gatgaggagc atatcaaggc cagtctggac tcagttggca tgtgggaaca tcgagacaaa
    41461 cgcttgggtt ctctatctgg gggacaaaag cagcgagcgg tgattgcgcg tatgtttgct
    41521 tctgaccctg atgtgtttat cctagacgag ccgacaacgg ggatggatgc aggaagtaaa
    41581 aatgaatttt acgaactcat gcaccacagc gcccatcatc atggcaaggc tgttttgatg
    41641 attacccatg accctgaaga agttaaggat tatgcggatc gcaatattca tctagtccgt
    41701 aaccaagact cgccatggcg ttgtttcaat gttcatgaga atggccagga ggtgggccat
    41761 gcttagttta ttatcttacg actttataca gcgcgccttt ttggcggtta ttgctatgag
    41821 tcttttctca ccggtattgg gaaccttcct catcttgcgt cgtcagagtt tgatgagtga
    41881 tacccttagc cacgtctcac tttcaggtgt agcctttggt ctggttttgg ggatttctcc
    41941 aactgtttct actattgcca ttgtcttgat tgcggcggtc tttctggagt atctccgtac
    42001 ggtttacaag agctttatgg aaatcgggac agctatcctc atgtcaacag gtctggctgt
    42061 ttctctgatt gtcatgagca agggtaaaag ctcgagttca atgagtttgg accaatatct
    42121 ctttggttcg atcgtgacta tcagtgaaga acaggtcatt tccctctttg tcattgcggt
    42181 ggttgttttg attttgacct ttctctttct tcgtcctatg tatatcttaa cttttgacga
    42241 agatacggcc tttgtggatg gcttgccagt tcgtaccatg tccattcttt ttaacatggt
    42301 gacaggggtg gctattgccc ttatgattcc tgcagcagga gctcttctgg tatcgaccat
    42361 tatggtcttg ccagctagta ttgccctgcg tctggggaaa aactttaaat cggttatgct
    42421 gcttgccagt gcgattggct ttttgggaat ggtagcagga ctttacattt cctactatgc
    42481 agaaacacct gcaagtgcaa gtattaccat tatttttgta actgtcttta tactaatcag
    42541 tttagtaaga cgttttatca aataggagac gaacgtgaaa aaaattagct tattactagc
    42601 cagtctatgt gccttgtttt tagtggcttg ttccaatcaa aaacaggcag atggtaaact
    42661 caatatcgtg acaacctttt accctgtcta tgaatttacc aagcaagtcg caggagatac
    42721 ggctaatgta gaactcctaa tcggtgctgg gacagaacct catgaatacg aaccatctgc
    42781 caaggcagtt gccaaaatcc aagatgcaga taccttcgtt tatgaaaatg aaaacatgga
    42841 aacatgggta cctaaattgc tagatacctt ggataagaaa aaagtgaaaa ccatcaaggc
    42901 gacaggcgat atgttgctct tgccaggtgg cgaggaagaa gagggagacc atgaccatgg
    42961 agaagaaggt catcaccatg agtttgaccc ccatgtttgg ttatcaccag ttcgtgccat
    43021 taaactagta gagcacattc gtgacagctt gtcagcagat tatcctgata aaaaagagac
    43081 ctttgagaag aatgcagctg cctatatcga aaaattgcaa gccttggata aggcttacgc
    43141 agaaggcttg tctcaagcaa aacaaaagag ctttgtgact caacacgcag cctttaacta
    43201 tcttgccttg gactatggac tcaaacaagt cgcaatctca ggactttctc cagatgcaga
    43261 gccatcagct gctcgcttgg cagaattgac agagtatgtc aagaaaaata aaatcgccta
    43321 tatctatttt gaagaaaatg cctcacaagc ccttgctaac acactttcaa aagaagcagg
    43381 tgtcaaaact gatgtcctca atcctttaga aagtctgaca gaagaggaca ccaaggctgg
    43441 agaaaactac atttccgtga tggagaaaaa cctcaaggct ttgaaacaaa caacagacca
    43501 agaaggccca gcaatcgaac ctgaaaaggc agaggatacc aagacagtcc aaaatggtta
    43561 cttcgaggat gcagctgtca aggaccgcac cttgagtgac tatgcaggta actggcaatc
    43621 agtttatcct ttccttgaag acggcacgtt tgaccaagtc tttgactaca aggctaagtt
    43681 gactggtaag atgacccagg ctgagtacaa ggcttactat acaaaaggct atcatacaga
    43741 tgtgactaag attaacatta ctgataatac tatggaattt gttcaaggtg gacaaagcaa
    43801 gaaatacact tacaagtatg tcggtaagaa aattttgact tacaagaaag gcaatcgtgg
    43861 cgtgcgtttc ctctttgaag ccacagatgc tgacgctgga caattcaagt atgttcagtt
    43921 tagtgaccac aatatcgccc cagttaaggc agaacatttc catatctttt ttggaggcac
    43981 aagccaagaa gccctctttg aagaaatgga caactggcca acctactacc cagataacct
    44041 atctggccaa gaaatcgccc aagaaatgtt ggcgcattga tgagaaatcg actagttcat
    44101 aagagctagt cggttttttg atactagatg gctaacttca ttatagacct ttcagaacta
    44161 aggaacttta aaaaaataaa taaaactctt gaaatattag gacttatatg ctagaatgta
    44221 gttagtgtat aaggttcatt agaacaccaa agcccctaac tagtgccata gttaagggct
    44281 tttttgacgt atcttagcga tttaacgggt gtttataggc tagtcagtcg gtctacttct
    44341 taccatctag ccatttgcag acgaaataca agataattcc agctataaca tctgctataa
    44401 tagtaagagc aagctctggt ataaggctca ttagtttcac ctcctctcac gaacccatag
    44461 gaacgtaatc ggtaaccgat gacaaaagta ttataccaca ctaaatttag atcatcaacc
    44521 tcacttaatg cttgaactat tgtagattat atgctaaaat gtagttaatt gataaggttc
    44581 attagaacac caaagcccct aactatggcc gtagttaagg gcttttttga cgtatcttag
    44641 cgatttaatg ggtgtttata ggctagtcag tcggtctact ccttactatc tagccatctg
    44701 cagacgaaat acaagataat tccagctata acatccgcta taatagtaag agcgagctct
    44761 atgataaggc tcattagttt cacctcctct cacgaaccca taggaacgta atcggtaacc
    44821 gatgacaaaa atagtatacc acaatacatt tagatcatca aggtcactta attcttgaaa
    44881 tatagggtct aggcgacaaa gtctttaaaa tcagaaaaac gcataatatc aggtgtgcaa
    44941 aaacttgata ctatgcgttt tattgtggga aggtttactc cattttctcc tgaaattgag
    45001 tttttgtcca gcctctgttt ttagggttgc taagaaaata atgtcatgtg gtgaatattt
    45061 gtaaatcagt cagcagacag aacgatactc ttcgaaaatc tcttcacatc atgtcagctt
    45121 cgtctttccg tgtccatggg ggacttgact tcatcagttt tcaaatctgt actttgagca
    45181 agctgagact agcttcctat ttgattttca ttgaatatca gaaacccatt ctccatcaaa
    45241 taattcgact gcgtctaata atttttggtc tggcacggtg tcagaaataa aggttgtgta
    45301 tttggagagg ggattaattt taaaaaatcc agtcttgtaa aatttagaac tatcaatcag
    45361 taagatagtt tcatgggctt tgtcaataat attctttttt gaaatagctt ggctgagaga
    45421 agcttcataa acatattggt catcaatacc tcttgctgaa caaaatgcta aatcgatatt
    45481 aaaatgatct aataaagaat tttccttatc gtaattgacc acggaacagg attgatgttt
    45541 gacctcgcca gatgtgataa agattttgga gctatcttta acagtttcag atagggtttg
    45601 tgcagtatgt aaaccatttg taaaaataat caaattatca agttcagaaa gatagggaca
    45661 aagttcgtag acagtagtac tggaatccag ataaacacac ataccagacc gaataaagtc
    45721 tttagcgaga ctagcgatta gtcttttttg cctagtactt tctccttccc gtatttgatg
    45781 agaaagttca attgtgttca tagaggacag ggtcacgtat ccgtgctttc ttttgataag
    45841 accttgattt tctaagaaaa ttaaatcacg acgtaaggta cttgtgctgg agaaagtgat
    45901 ttctgccagc tcttttacgg caattctttt tttcttttta ataatttcaa tcaattcaag
    45961 tacacgttca tcttttatca taagctcctc ctaatttat
//
LOCUS       DAVHSI010000017        42149 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.017, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000017 DAVHSI010000000
VERSION     DAVHSI010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.017"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..630)
                     /locus_tag="VVR21_001035"
     CDS             complement(<1..630)
                     /locus_tag="VVR21_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054935.1"
                     /translation="MRINDFHNILELIKQDVLQSEAEYLKLLKVVGNNQKYDFRSQLS
                     IYDKNPEATACAKFDYWREHFNRTVMRGQKGIPILEDYGTYKKVDYIFDISQTVSKNR
                     DVNEVNLWRFDKEAHRDVLKEMIKAEGYEESESTLENIFSLSRLYGDEKIDSLMNELR
                     ISDEDRISFTKFARDSVSYAVASRFKLDYPMDKELLKENFAMLDSISLMS"
     gene            complement(717..2144)
                     /locus_tag="VVR21_001036"
     CDS             complement(717..2144)
                     /locus_tag="VVR21_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEU6054936.1"
                     /translation="MTIDEIKKLIQNGEKIDVEFKESRNALTKDVFDTVCSFNNRNGG
                     HILLGVNDKRDIVGVSEDKVDKIIKEFTTSINNSQKMYPPLYLLPEVFELDSKKVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHAELVYKLYARKQGSYFVNKVYPNLDIEFL
                     DTDVIDKAKRMAVARNKNHVWENMSYEELLRSANLILTDPETKHEGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIAFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDEKIMIENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTRLYSGVDPLFEEGDIFRTIIPLKKIA
                     TQKVGGSGVAQDVAHSVAQDVAHDKIALAEFIKEKIRGNNKITRKAIADEAGVSVKTI
                     ERTIKEMDNLQYVGSGSNGHWELNE"
     gene            complement(2164..2343)
                     /locus_tag="VVR21_001037"
     CDS             complement(2164..2343)
                     /locus_tag="VVR21_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEU6054937.1"
                     /translation="MKDTFMDTAKVMSKGQVTIPKRIRELLDLQNGDYVTFVVNKDKV
                     QIQNSKTFIEENIDK"
     gene            complement(2427..4133)
                     /locus_tag="VVR21_001038"
     CDS             complement(2427..4133)
                     /locus_tag="VVR21_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEU6054938.1"
                     /translation="MNLVIAEKPSVAISIAKVIGATKKKDGYYEGNGYKVSWCVGHLI
                     KMANPESYDEKYAKWNMADLPIIPKEYKYEIAKSTKKQFTILKKLMNDKDIDIVINAC
                     DAGREGEAIFRLVYNQANCKKRMKRLWISSMEDSAIKEGFDNLKDGSSYDNLFESAQA
                     RAIADWLVGMNLSRLYSCLYKQNYSVGRVQTPTLAMIVKRDGEIANFKKEKYFTVELS
                     LNGFTLSTDRIDDEITAEQLLNLVGDKIEITDVIQKEKITKPELPFDLTTLQRECNKY
                     FGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMIVSTVNNILGKNDFDTERIKTVF
                     NSKKVTDHHAIIPTASSMNENLTSLPESELKVYELILNKLHASVGYPLIENTTKIVAE
                     FDGFEFTSSGKVIVDDGFTKYLNEYAKKKNEDTVLPDVKIGYSLDIKDKEIKEKYTQP
                     AKHFTEDLLLKAMELAGNDALEKGVEVERKGLGTPATRAGIIENLIFKGFVERDKKNL
                     IATHKGISLVTIVADTFKSAETTAKWEMELSDIAQGQSSEENFLEAIENEIKEVVSTY
                     TK"
     gene            complement(4231..6417)
                     /locus_tag="VVR21_001039"
     CDS             complement(4231..6417)
                     /locus_tag="VVR21_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEU6054939.1"
                     /translation="MKTSLKNKRITAIVVAFTLLMVGVLGVLKVGAKTVFASNEPPEK
                     YETYYELKFEDHTSDDTFRGFYHLGKGNKEGQPLNFKFSLSKSFEEKGGVVVDKYNET
                     FTNENMDKVNQLDDLRYMTKKPYPYYRIHNIGTGAFTSIVSPRDKDNYYIGDITENAE
                     ERTVKGKKANVIVYTCPVLQLNRNIEKVTVDYEGEFKEETKNSIIGRVKEANPNINNV
                     KEIKIVKDKLIIETWNRFHTGVPYLELPLEDLYKRVANASAQTDNKDTKDEESQTKSE
                     VKIKYQYQDGNVYKEYSASFDKNQMIDASDLEMLPDNMSFNDDFVSYTVKGDGSDSII
                     RIVKKLESNAQTQTEKPKTEDKGIQTELSKDDISKMEKESKELQEKLDKLNQEIKDKD
                     KLSDKQKEKIKDLEEKIDKLKEKLEKGKDDKDLSADIKKEIEKLTEKIKELEKKTNEV
                     GKATVTHNPTVTPISPISGMKTGTGNFPQTSVSDTGKGSSSQDNTGKITKDTNIGKNN
                     DKEKEVRYPNKLTPKQPANNSSQDSSMDGSSKNVNTNKGVASAPSKARGTVTENKDNA
                     NKDYPIHHNDSKDNKETDMYSADARQFVTFTTKNGKTFHLIINHDEDSENVMLLTEVS
                     EDDLLNMVEKKEAPKQEITKEEPEKEEPKPVKKEESSNMGTYLILILVVAGALGAGYY
                     FKVVKKKEDKELEGFEEEDDDFFSEAEESENEVDETETEDKEDELE"
     gene            complement(6395..6631)
                     /locus_tag="VVR21_001040"
     CDS             complement(6395..6631)
                     /locus_tag="VVR21_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6054940.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITISDLMAKVNREKAEVKKEKTNENQFEK"
     gene            complement(6644..8776)
                     /locus_tag="VVR21_001041"
     CDS             complement(6644..8776)
                     /locus_tag="VVR21_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6054941.1"
                     /translation="MGKKLKKDFKERQRARIEKERLQSNSSIEPEENKLKHNDDYRGK
                     IVHDKDRFQDKVHEKVSKRSAETELNGKTSKRNARYRSPETGSVSQEEIGKADYDTEV
                     KDGKIYDPLGKDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLQHKVEDTKGFSKSQKA
                     QKKNYKRKNYSDKLYTRKKDKEAKEEKADSKKSGKEAILDREKKNRLSKEQERAFKNK
                     TSKVSALSGLAKGSETVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKNYSDKKKAK
                     KGYDLTNKDYKIRKRKSKLEFRDAKEELKKTQEYQKANNFKRFQKRKQMKDSIKRKNK
                     SRLRDRIKEGLIGSLKSSKEVILRKAKGLMIIFIGLIILGTFFINFAGTGMTGFMNST
                     SSVLTTSYLSKPNVLSEINENFSEMEKELQSEVDNVEENYPGYDEYILNNTEYIGHNV
                     HELLSYITSRCGEVKNASEVSSVLNELFKSMYDLEYKEEVEIRYRTVTETYTDEDGNE
                     YTESHEEPYEYKKLIVTLHKKEMDSIIRKVFANYPDNLKHYEALFLAQGNMGEAFGNS
                     DLIASNGGIGGGKEYEASTEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGG
                     NACDMYRNYTFTSDKSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGRI
                     RVTTLDDWIASFCQHHPVGFGFPPNVNR"
     gene            complement(8781..11210)
                     /locus_tag="VVR21_001042"
     CDS             complement(8781..11210)
                     /locus_tag="VVR21_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6054942.1"
                     /translation="MKDKRKIQQLKLEQNQKKLRSQKQDLKQNKGKSKKDRGGLLDLI
                     FRKEPKRYTVEDTIPYLRLLKSGICQIDEKHFNKSIAFEDINYQLALEEDRDLIFNQF
                     ANFLNSFDPSVSIEFSYINQLGRNEEMKSAIQIPDKKDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLEIDILSSLKSMGVRAESLNGEERLKILHD
                     VLNPNKTFEFSYKDLKKKESTKTYIAPDEFNFTPSRYFKFGKFIGAASHFQILASELS
                     DRMLAEFLDIDDNINISFHIKAIEQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVTIIFMNFARTIQRLDNTISQISSIANKH
                     NCKLKRLDHSQEQGLISVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSANSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILTTDDDVIICDPEG
                     EYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYEKYFENPKPCNMPILQNLYDMLKNQEEKVGKKLATEMEIY
                     VTGSLNVFNHQSNVDLNKQLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISQPQLKYVTNSNAGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(11122..11511)
                     /locus_tag="VVR21_001043"
     CDS             complement(11122..11511)
                     /locus_tag="VVR21_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU6054943.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLIGIPIYLFMR
                     KVVPNDIAVIFLIVSTLPIFFITLFEKDGLSFEKYFKYIYLHKFYQPQKRVRKEVYLE
                     RQKKNSAAKVRTKPKEVKKSKTGLKAK"
     gene            complement(11515..11778)
                     /locus_tag="VVR21_001044"
     CDS             complement(11515..11778)
                     /locus_tag="VVR21_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6054944.1"
                     /translation="MNKRKTVLIAVAVGTGILAVMDRIRLHIKENDLEERTKDIGRCH
                     NDFCLMQERYNRSTDEQIASIQEEIGSVYEHIEELSKGKEDGR"
     gene            complement(11796..12659)
                     /locus_tag="VVR21_001045"
     CDS             complement(11796..12659)
                     /locus_tag="VVR21_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054945.1"
                     /translation="MFGIFDKIEEFFKDLLLGGIQANLESMFLDINDKVGAIATDVGK
                     TPMGWNGQVFSFIKSINDSVIIPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFQFSMAVFDVAQHMVNKAAGVINTSAVISGDQIVTMVEGLKDKG
                     LGELVMILFETSLIKVAIQVISIVIMLVVYGRMFEIYVYSSVSAIPFATMGNKEWGQI
                     GTNYIKGLFAIGLQGLFLMVCLGIYAVLVKTIQITDIHTSTFTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            complement(12679..12894)
                     /locus_tag="VVR21_001046"
     CDS             complement(12679..12894)
                     /locus_tag="VVR21_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEU6054946.1"
                     /translation="MEFFTQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLK"
     gene            complement(12898..13209)
                     /locus_tag="VVR21_001047"
     CDS             complement(12898..13209)
                     /locus_tag="VVR21_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU6054947.1"
                     /translation="MKQEMININANLLAEPTFSSFDKEGETVEVVNFTLVKKYGKGKE
                     YINCAAYGEKSETAKAFEKGDLIHIFGYFKKREKDGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(13375..15159)
                     /locus_tag="VVR21_001048"
     CDS             complement(13375..15159)
                     /locus_tag="VVR21_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU6054948.1"
                     /translation="MIDKILKDIKGLFKVQDKSKFFKQNIPYLAFFYVGNIFSHHVRA
                     YTGGDVIDKIFQGILELNTMSFIPSIHPIDILMGVEVAVLIKFIVYTKGKNAKKFRQG
                     KEYGSARWGTRKDIEPYVDEKFQNNILLTQTERLTMNGRPANPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYCVTDPKGTIVIECGKMLEDNGYEIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGEGEKAGEDFWVKAEKLYYTALIGYIFYEAPREEK
                     NFATLLDMIDASEVREDDETYMNPIDRLFEALEKKEPTHFAVKQYKKYKLAAGKTAKS
                     ILISCGARLAPFDIQELRDLMKEDELELDTLGDRKTALFVIISDTDDTFNFVVSIMYS
                     QLFNLLCDKADDEYGGRLPVHVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQA
                     QSQLKAIYKDNADTIVGNCDSTLFLGGKEKTTLKELSETLGKETIDLYNTSETRSNAN
                     SYGLNYQKTGKELMSQDEITVMDGSKCIFQLRGVRPFLSDKFDITKHKNYKLLEDFNK
                     KNAFDIEEYIKRKGKAKLNRETVITRVQ"
     gene            complement(15156..15641)
                     /locus_tag="VVR21_001049"
     CDS             complement(15156..15641)
                     /locus_tag="VVR21_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEU6054949.1"
                     /translation="MINEEIARKTLNMEVKAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKESGKYSVF
                     FQAKDMKVMDKAFKHALSESEKKTERKESIHKNIEKFKEMAKNALSKDKVKNKQKEQS
                     L"
     gene            complement(15638..16489)
                     /locus_tag="VVR21_001050"
     CDS             complement(15638..16489)
                     /locus_tag="VVR21_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6054950.1"
                     /translation="MIKELEKVMIEDVEYSFNPEKEYIKDGHAYCKVCHERKDGKALE
                     FFGKQMIFKTACKCDRDREVKEKERQKQLEIERLKSICFTSIIQWSYTFENYQGKENQ
                     SLIIAKNFVKDYELMKKENIGLLFYGTVGSGKTYLACSIANALIEQYQISVKIRNFSQ
                     IINELQKGGFDIDKNAYIESLVNTSVLILDDLGIERDTSYAKEQVYNIVNNRYLKHKP
                     TIFTTNLSYSQIENCTESVEYQRIYSRIIEMCIPVMVLGENYRKVIQEEKLKRNKERL
                     LTGGERT"
     gene            complement(16486..17256)
                     /locus_tag="VVR21_001051"
     CDS             complement(16486..17256)
                     /locus_tag="VVR21_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6054951.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWVDKEGRVFIYFTVEEIMRRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNVIYVKDFMSIIAVKENDFQKSKNLTSEVRDFNLRSKENELQEVQNVDSNYI
                     ENNKSKYSKREYSFGKSGLGTFQNVFLKDEDIGELQIIMAGELDNYIERLSTYLQSTG
                     KTYKDHKATILSWFYKDQGSKKKTNIPTWEEYNKGVHL"
     gene            complement(17347..17628)
                     /locus_tag="VVR21_001052"
     CDS             complement(17347..17628)
                     /locus_tag="VVR21_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054952.1"
                     /translation="MRWIIKIILFPISLVLSILTAFLTFLLGIGTALLYLLMMFCIFG
                     AIASFLQKEVTIGIEALIIGFLVSPYGIPMVGATVIAFLQGINEAIKSI"
     gene            complement(17793..19151)
                     /gene="rlmD"
                     /locus_tag="VVR21_001053"
     CDS             complement(17793..19151)
                     /gene="rlmD"
                     /locus_tag="VVR21_001053"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6054953.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVECIALIQR
                     VK"
     gene            complement(19225..20199)
                     /locus_tag="VVR21_001054"
     CDS             complement(19225..20199)
                     /locus_tag="VVR21_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU6054954.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVYAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKTLSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(20273..20887)
                     /gene="pmp23"
                     /locus_tag="VVR21_001055"
     CDS             complement(20273..20887)
                     /gene="pmp23"
                     /locus_tag="VVR21_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU6054955.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(20887..21861)
                     /locus_tag="VVR21_001056"
     CDS             complement(20887..21861)
                     /locus_tag="VVR21_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU6054956.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(21869..23125)
                     /locus_tag="VVR21_001057"
     CDS             complement(21869..23125)
                     /locus_tag="VVR21_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU6054957.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITAREFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(23187..23618)
                     /locus_tag="VVR21_001058"
     CDS             complement(23187..23618)
                     /locus_tag="VVR21_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054958.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(23620..24222)
                     /locus_tag="VVR21_001059"
     CDS             complement(23620..24222)
                     /locus_tag="VVR21_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU6054959.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(24206..25045)
                     /gene="prmC"
                     /locus_tag="VVR21_001060"
     CDS             complement(24206..25045)
                     /gene="prmC"
                     /locus_tag="VVR21_001060"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU6054960.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADISQEALDLARENAKNQNLQ
                     IFLKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDATDYLKDSGKIYLEIGYKQGQCVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(25045..26124)
                     /gene="prfA"
                     /locus_tag="VVR21_001061"
     CDS             complement(25045..26124)
                     /gene="prfA"
                     /locus_tag="VVR21_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU6054961.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(26134..26613)
                     /locus_tag="VVR21_001062"
     CDS             complement(26134..26613)
                     /locus_tag="VVR21_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6054962.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(26603..27202)
                     /locus_tag="VVR21_001063"
     CDS             complement(26603..27202)
                     /locus_tag="VVR21_001063"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU6054963.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            27325..27507
                     /locus_tag="VVR21_001064"
     CDS             27325..27507
                     /locus_tag="VVR21_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU6054964.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            27644..29017
                     /gene="mnmE"
                     /locus_tag="VVR21_001065"
     CDS             27644..29017
                     /gene="mnmE"
                     /locus_tag="VVR21_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU6054965.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(29064..29999)
                     /gene="dapA"
                     /locus_tag="VVR21_001066"
     CDS             complement(29064..29999)
                     /gene="dapA"
                     /locus_tag="VVR21_001066"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU6054966.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(30055..31131)
                     /locus_tag="VVR21_001067"
     CDS             complement(30055..31131)
                     /locus_tag="VVR21_001067"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU6054967.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(31473..31545)
                     /locus_tag="VVR21_001068"
     tRNA            complement(31473..31545)
                     /locus_tag="VVR21_001068"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31510..31512),aa:Thr,seq:ggt)
     gene            complement(31645..32154)
                     /locus_tag="VVR21_001069"
     CDS             complement(31645..32154)
                     /locus_tag="VVR21_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU6054968.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(32152..32248)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            32277..32708
                     /locus_tag="VVR21_001070"
     CDS             32277..32708
                     /locus_tag="VVR21_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU6054969.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            32790..33167
                     /gene="mscL"
                     /locus_tag="VVR21_001071"
     CDS             32790..33167
                     /gene="mscL"
                     /locus_tag="VVR21_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU6054970.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(33209..34303)
                     /gene="hemH"
                     /locus_tag="VVR21_001072"
     CDS             complement(33209..34303)
                     /gene="hemH"
                     /locus_tag="VVR21_001072"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU6054971.1"
                     /translation="MKKAILMMTFGSPEETTFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITHQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKIIFSAHSVPIFALDFGDPYIDQIFENSKLVVEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTAHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            34457..35680
                     /gene="pepT"
                     /locus_tag="VVR21_001073"
     CDS             34457..35680
                     /gene="pepT"
                     /locus_tag="VVR21_001073"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU6054972.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(35716..36345)
                     /locus_tag="VVR21_001074"
     CDS             complement(35716..36345)
                     /locus_tag="VVR21_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054973.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            36310..36531
                     /locus_tag="VVR21_001075"
     CDS             36310..36531
                     /locus_tag="VVR21_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054974.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(36802..37813)
                     /locus_tag="VVR21_001076"
                     /pseudo
     CDS             complement(36802..37813)
                     /locus_tag="VVR21_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(38039..41158)
                     /gene="phtE"
                     /locus_tag="VVR21_001077"
     CDS             complement(38039..41158)
                     /gene="phtE"
                     /locus_tag="VVR21_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU6054975.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(41368..>42149)
                     /gene="phtD"
                     /locus_tag="VVR21_001078"
     CDS             complement(41368..>42149)
                     /gene="phtD"
                     /locus_tag="VVR21_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU6054976.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPS
                     ADNLYKPSTDTEDTEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNA
                     VETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT        11557 a         8892 c         7042 g        14658 t
ORIGIN      
        1 gctcataaga gaaatgctgt caagcattgc aaagttttcc tttaacagct ccttatccat
       61 tggatagtct aacttaaatc ttgaagctac tgcataactt accgagtccc ttgcaaactt
      121 ggtaaaggat attctgtcct catcagatat tctaagttca ttcatcaagc tatctatttt
      181 ttcatctccg taaagcctac ttaaagaaaa gatattttct aaggtgcttt cactttcttc
      241 atagccttca gcttttatca tttcttttaa tacatctcta tgagcttctt tatcaaatct
      301 ccaaagattt acctcattga catctctgtt tttggaaact gtctgactaa tatcaaagat
      361 atagtccacc tttttgtatg tgccatagtc ctctaaaatg ggaataccct tttgacctcg
      421 catgacagtt cggttaaagt gttctctcca gtagtcaaac ttggcacaag ctgtcgcttc
      481 aggattttta tcataaatac ttaactgact tctaaaatcg tacttctgat tgttcccgac
      541 aacttttaag agcttcagat actctgcttc actctgcaga acatcttgtt ttatcagctc
      601 caaaatgtta tgaaaatcat ttattcgcat gtttacctcc ttcttttttt acaaacaaaa
      661 aaggcggtta gattttactc taatcacctt taaattctgt gtgctacaac ttactgctat
      721 tcattcagtt cccaatgacc attacttcca cttcctacat attgtagatt atccatttct
      781 ttaatggttc tttctatagt ctttacacta actccagctt catctgcaat tgcttttctt
      841 gtaatcttgt tgtttcctct tattttttct tttataaact ctgcaagagc tatcttatcg
      901 tgagcgacat cctgagcgac actgtgagcg acatcctgag cgacaccgct tcctccaact
      961 ttttgagtcg ctattttctt caaaggaata atcgttctaa atatatctcc ctcctcaaac
     1021 agaggatcaa cacctgaata tagccttgta tatttatagg tgtttctcat acctgaacca
     1081 agctcatcag caagtcctat ttctctaaat acttttgaaa tagccggatt tttaggaaaa
     1141 ggttcaaact tttgtaaatc caatgctccc atgccatgag ctaagttact gttttcaatc
     1201 ataatcttct catcgtcaat aatcattttt gcagggaaac cacttgaata atctctgtga
     1261 gccaatgtat tagaaacaat ttctctaagt attctatccc ttgcattgac atttacaatt
     1321 ccgtctaaga caaataagtc attcaaatgc ttctgtccaa acgcaataag cctatcgtag
     1381 ctatcaatca gatttgttat gacaacatct ctatcgtcat acctatcctt gttttcaact
     1441 ctaaatattg catcagtttt atgctgtggg agaactgaca taatagagtt gtcttttcca
     1501 aataacaaaa ttgccgctaa tgtaatgccc tcatgctttg tttcaggatc tgtcagaatg
     1561 agatttgcac ttcggagcag ttcctcataa ctcatatttt cccagacatg atttttattt
     1621 cttgctactg ccattctctt ggctttatca ataacatcag tatcaagaaa ttctatatcg
     1681 aggtttggat acaccttatt cacaaaatag cttccctgtt tcctcgcata tagcttataa
     1741 acaagttctg catggtctgt gatattgatg tctccttcat aagacctgtc ccatattctt
     1801 ccgttatgcc tgcatacctg ataaccttca ggtactcgga tataaatcac ttttttactg
     1861 tcaagctcaa atacttccgg taataaataa agtggtgggt acatcttctg cgaattgttg
     1921 atagatgttg taaattcttt aataatcttg tcaactttat cttcactaac accaacaata
     1981 tctcttttat catttacacc aagtaaaata tgtcctccat ttctattgtt gaaagagcat
     2041 actgtatcaa agacatcttt ggttagagca ttcctcgatt ctttaaattc aacatctatc
     2101 ttttctccat tttgaattaa cttttttatt tcatctatag tcatctttgt tgtttcacca
     2161 cctttattta tcaatgtttt cttcaataaa agtcttggag ttttgaattt gcactttatc
     2221 tttattgact acaaaagtaa cataatctcc attttgtaag tccaaaagtt ctcttatcct
     2281 ttttggaata gtaacctgcc cttttgacat aacttttgca gtatccataa atgtatcttt
     2341 catacctgtt tcctttctcc ctacttttcc tacaaaagat tatatcattt ttagggcatt
     2401 ttttccacct tgaaattagt ggcatcttac ttggtataag tggaaaccac ttcttttatc
     2461 tcattttcaa tcgcttctaa aaagttttcc tctgaagatt gcccctgtgc aatatccgat
     2521 aactccattt cccactttgc tgttgtttct gctgatttaa aagtatcggc tacaatcgtt
     2581 acaaggctga ttcccttatg tgtagcaata aggttctttt tatctctttc tacaaatccc
     2641 ttgaaaatca gattttcaat aatccctgct cttgttgcag gtgttccaag tccttttcgc
     2701 tcaacttcta cacctttttc caatgcgtca tttcctgcaa gctccatcgc ctttaggaga
     2761 agatcttccg taaaatgctt agctggttga gtgtattttt cttttatctc tttatcttta
     2821 atatcaagac tataaccaat ctttacatcc ggaagcactg tatcttcatt tttctttttc
     2881 gcatattcgt ttaggtattt ggtaaagcca tcatctacaa tcacctttcc actacttgta
     2941 aattcaaatc catcaaattc agccacaatc ttcgttgtat tctcaattaa aggatagcct
     3001 acacttgcat gtagcttatt taaaataagt tcatatacct tcaattcact ttccggaaga
     3061 gaagttaagt tctcattcat actgcttgct gtcggtataa tcgcatgatg gtctgtaacc
     3121 tttttagaat taaataccgt cttgatacgc tctgtgtcaa aatcattctt tcctaaaatg
     3181 ttattaaccg tacttacaat catatcttcc gtaaggcatc tgctgtctgt tcttggatag
     3241 gtaatcagtt tcttttcgta aagactttga gcataatcaa gtgtctgctt agctgagtat
     3301 ccaaaatatt tattgcactc tctttgaagc gtcgtcaggt caaatggcag ctcaggcttt
     3361 gttatctttt ccttttgaat aacatcggta atttctatct tatcgcctac taaatttaag
     3421 agctgttccg ctgttatttc atcatcaatt ctatctgttg atagtgtaaa gccattaagg
     3481 cttaattcca ctgtaaaata tttttctttc ttgaaattgg ctatctcacc atctcttttt
     3541 acaatcattg caagggtagg tgtctgcact ctgcccacac tgtaattttg cttgtataga
     3601 cacgaataca gtctgcttaa attcattccc acaagccaat ctgctattgc tcttgcttgt
     3661 gcagactcaa atagattatc gtaagaactt ccatctttta ggttatcaaa gccctctttt
     3721 atggcactat cttccattga tgaaatccaa agacgcttca ttctcttttt acaatttgcc
     3781 tgattatata caagcctgaa gatggcttct ccttcacgcc ctgcatcgca ggcatttatc
     3841 acgatgtcta tatccttatc attcatcagc tttttaagaa tcgtaaattg tttctttgta
     3901 gactttgcaa tctcatactt atattccttt ggaataatcg gtaaatccgc catattccac
     3961 ttagcatact tttcatcata gctttccgga tttgccattt taattaaatg tccaacacac
     4021 cagcttacct tatatccgtt tccttcataa tatccgtctt tcttctttgt tgctccgatc
     4081 acttttgcaa tagaaattgc aacacttggc ttttcagcaa ttactaaatt catctatttt
     4141 ttcctcctgt ttttcaaaat aatagggcgg aagatgttac tctcccgccc tgtcttttgc
     4201 accaaatatt gtatagtttt gggtgcaaat ttattccaat tcatcttctt tatcttctgt
     4261 ttctgtttca tctacttcat tttcactttc ttctgcctct gaaaagaaat catcatcttc
     4321 ctcctcaaag ccttcaagct ccttatcttc ttttttctta acgaccttga aataatatcc
     4381 tgcacctaat gctcctgcta ctacaagaat gagaattaag taggttccca tattgctgct
     4441 ttcttctttt tttactggct taggttcttc tttttcaggt tcttcctttg taatttcctg
     4501 ttttggagct tctttctttt caaccatatt aagaagatca tcttcggata cttctgttag
     4561 gagcatgaca ttttcgctat cctcatcgtg attgatgatt aaatgaaagg tcttgccatt
     4621 cttagtagta aaggtaacaa actgtcttgc atccgctgaa tacatatccg tttctttatt
     4681 atctttactg tcattatggt gtattggata atccttgttc gcattatcct tattttccgt
     4741 aacagttcct cttgcctttg atggtgctga cgcaactcct ttattggtat ttacattctt
     4801 acttgaacca tccatagagg aatcctgact gctgttattg gcaggctgtt tcggtgtcag
     4861 cttattggga taacgaactt ctttttcttt gtcattattc ttaccaatat ttgtgtcctt
     4921 tgtaatcttt cctgtattat cctgtgatga tgagccttta cccgtatcac ttacagatgt
     4981 ttgaggaaag tttcctgttc ctgttttcat tccggagata gggctgattg gtgttacagt
     5041 aggattatgc gtaactgtag ccttgccaac ctcattcgtc tttttctcaa gctccttaat
     5101 tttctcagtt agcttctcaa tctccttttt aatatccgcc gataaatcct tatcgtcttt
     5161 gcccttttca agtttttcct tcagcttatc tattttttcc tcaaggtctt tgattttctc
     5221 cttttgcttg tcgcttaatt tatccttgtc cttaatctcc tgatttagct tatcaagttt
     5281 ttcctgaagt tccttagatt ccttttccat tttggaaatg tcatctttgc taagctctgt
     5341 ttgaattccc ttatcttcag tttttggctt ttctgtctgc gtctgagcat tactttctaa
     5401 cttctttaca attcggataa tactatcgct tccatcacct tttactgtgt agcttacaaa
     5461 atcgtcatta aaactcatat tatccggaag catttcaaga tcagacgcat caatcatctg
     5521 atttttgtca aaggaagctg aatactcctt atatacattt ccgtcctgat attgatattt
     5581 gatctttact tcactttttg tctgactttc ctcatcctta gtatccttat tgtctgtttg
     5641 agctgacgca ttcgctaccc tcttatataa atcctctaaa ggtaattcaa ggtagggtac
     5701 accagtatga aatctattcc atgtttcaat aatcagcttg tccttaacaa tcttaatttc
     5761 ttttacattg ttgatattgg gatttgcttc ttttactctg ccaataatag aattctttgt
     5821 ttcctcttta aactctccct catagtcaac agttactttc tcaatatttc tatttaactg
     5881 tagaacaggg caggtataga caatgacatt tgctttcttt ccttttacgg ttcgttcttc
     5941 tgcattttct gtaatatctc caatatagta attatcctta tctcttggag aaacgatact
     6001 tgtaaaagca cctgtcccta tattatgaat tcgataatat ggatagggtt tctttgtcat
     6061 atatcttaga tcatctaact gatttacctt gtccatattt tcattggtaa aggtttcatt
     6121 atacttatcg acaactacac cgcccttttc ttcaaaggat tttgataagg aaaatttaaa
     6181 gttcaatggc tgaccttcct tatttccttt tccgagatga taaaatcctc taaaggtgtc
     6241 atctgaagta tgatcctcaa atttcagttc ataatatgtt tcatattttt caggcggttc
     6301 atttgatgca aatactgtct ttgcaccaac ttttaacacc cctaaaactc caaccattag
     6361 cagggtaaaa gctacaacaa tggctgtaat tcttttattt ttcaaactgg ttttcatttg
     6421 ttttctcctt tttcacttct gctttttctc tgtttacttt tgccattaaa tcactgattg
     6481 taatgttgtt ctttctgcaa atggcaataa tttcttcgtt ttcaagttct tcctcacgaa
     6541 tgaacaaagg ctccaattct tcatcaatca gagccttttt atcttttaat ttctttattc
     6601 tgttttttac tgctgtaagt tcttttttca aattgtgtcc tccttatctg tttacatttg
     6661 gcggaaagcc gaagcctact ggatgatgct gacaaaaaga tgctatccaa tcatctaaag
     6721 ttgttactct gattcgaccg atattatcta ttactttgcc atcgcctata taaatgccta
     6781 catgaccata agtaagtcct gctgtacttc cgctgctact actttccacc gcaacaagca
     6841 ttcccacctt gagttttgat ttgtccgatg taaaggtgta gtttcgatac atatcacagg
     6901 catttccgcc aatatatcca agtcctgcat tttgatagac ctgtgatacc cacatggcac
     6961 accagcctgc ccccggagat ggcgtaatgt atgcagcatt tacaatcttc ttttgaactt
     7021 ccgtagaagc ctcatactct tttccgcctc cgatacctcc attggaagca ataaggtcgc
     7081 tattaccaaa ggcttctccc atattgcctt gagcaaggaa tagggcttca tagtgcttca
     7141 gattgtcagg atagtttgca aaaacctttc tgataatgct atccatctct tttttatgaa
     7201 gcgttacaat cagtttcttg tactcgtaag gttcttcatg gctttcggta tattcatttc
     7261 catcttcatc ggtataagtt tctgtaactg tcctatatct gatttccact tcttccttat
     7321 actcaaggtc atacatggac ttaaaaagct catttaatac ggagcttact tccgatgcat
     7381 tctttacttc cccgcacctt gatgtaatgt aggataaaag ctcgtggaca ttatgaccga
     7441 tgtactctgt gttatttagg atgtactcat catatccggg ataattttct tctacattgt
     7501 caacctcact ttgaagctcc ttttccatct ccgaaaaatt ctcattgatt tcacttagga
     7561 catttggctt tgacaaatag cttgttgtaa gaacagaact tgtggagttc ataaagcctg
     7621 tcattcctgt tcctgcaaag ttgataaaga aagttcccaa aataataaga cctatgaaaa
     7681 taatcataag tcccttcgct tttcttaata taacttcctt tgaactttta agacttccta
     7741 taagcccttc cttaatgcga tctctaagcc ttgacttatt cttcctttta atggaatctt
     7801 tcatctgctt tcgcttctga aatcgcttaa agttatttgc tttttgatac tcctgtgtct
     7861 ttttcagctc ctctttggca tctcgaaact caagtttgga ttttctcttt ctgattttat
     7921 agtccttatt cgtaaggtca tatccttttt ttgctttttt cttatccgag tagttcttaa
     7981 tgccatgaat gagctttgag cttgtatctg ctgtcttctc tcctgcctct accccttgat
     8041 tttcatcgct tccatgagat aggtaatctc ttacggtttc acttccttta gcaagtcctg
     8101 ataaagcgga cactttagaa gtcttattct taaaggctct ttcctgttct ttagaaagcc
     8161 tgtttttctt ttctctatca agaatggctt cttttccgct ttttttacta tccgcctttt
     8221 cctctttggc ttctttatcc ttttttctgg tatagagctt atcagaatag ttttttctct
     8281 tataattttt cttttgagct ttttggcttt ttgaaaagcc ttttgtatct tctactttat
     8341 gttgcagatt atcctctaca tcataggttg actcaaaata gtcgctgtcc ctaaagtcat
     8401 tgtcatatct gtctatgatt ccgtcattgt cgaggtcttt tcctaaagga tcatagattt
     8461 ttccatcctt aacctcagta tcataatccg ctttcccgat ttcttcctga cttacacttc
     8521 ctgtttcagg acttctatac cttgcatttc ttttagaagt ttttccgttt aattcagttt
     8581 ctgcacttct cttactgacc ttttcatgaa ccttatcttg aaatctgtct ttgtcatgga
     8641 cgattttccc tctgtaatca tcgttatgct ttagcttatt ttcttcaggc tctatgctgc
     8701 tattactttg cagcctttcc ttttcaatcc ttgccctttg cctttcctta aagtcctttt
     8761 tcagtttctt tcccataagc ctacctcact tcttcaggct tggttgtcat tttctgataa
     8821 aggattgtgt ctttcgggaa tttatcaagg aaagggacaa tggtatttcc aaagaacaaa
     8881 agtccttctc ctgcattgga attggttaca tattttagct gtggctgtga gattttaagt
     8941 ttccttgcta aaatctctct atctcctgaa gcctgattaa gcattaaaac aaagtccgta
     9001 ttatcaaaga tattttcaat ttccttgctc ataagtaagt ctttgacatt ttgtgtaatg
     9061 cctgtcggga ttcctcccca cttacgaaat cttttccaaa tttctacgga ataggaagct
     9121 gtctgctcat cttttaacaa taagtgaaac tcgtcgatat agtaccttgt agccttattt
     9181 cctctgtttt gcgatacctt attccacacc tgatcctgaa taacaagcat tccgattttt
     9241 ttaagctgtg agcctaactc cttaatatca aaacaaagta gctgcttatt taagtccaca
     9301 ttggactgat ggttaaatac atttaaggat cctgttacat aaatctccat ttccgttgcc
     9361 agctttttac cgactttttc ttcctgattt ttgagcatat catacaggtt ttgaagaatc
     9421 ggcatattac aaggctttgg attttcaaaa tacttttcat aaatcttagg aaggcatctg
     9481 tctataaccg acttttcttc tgctgtaaga ccactaccgc caactactaa ttcaagcatc
     9541 gacataatga agtttgcttt atctttcagt ggtgcgtccc catcgccata gttcatattt
     9601 atatctaaag gattaaggta gtcttttgac ttactgctga cctttattac ttctccttta
     9661 aactgacgaa caaggtttcc gtactcgcct tccggatcgc agataataac gtcatcatcc
     9721 gttgtaagaa tggcatttgc catttctctt tttgcactaa aggatttacc acttcccgga
     9781 gttccgagaa ttaaaccgtt cgggtttttc aatttctttc tatcagccat aatcaggtta
     9841 tggcttaggg catttagtcc ataatacaaa ctgttcgccg aatttatgaa aagctcctct
     9901 gtggtaaaag gcataaatac tgccgtagat gatgaggtta gtcctctgtc aatttcaatc
     9961 ttatttaccc caagtggaag tacactgatt aagccctgct cctgtgagtg atcaagtctt
    10021 tttaacttgc aattatgctt attggcaatg gagctgattt gagaaatggt attgtccagc
    10081 ctttgaattg tccttgcaaa gttcataaag atgatggtta cgacaaacat acgctcatct
    10141 cttgtctgaa ggtcttttaa gaggcttttt acatcttccc cataggtgat taaatcactt
    10201 ggaagaatgt ccatatcata accgcttctt acagcctttt tattctcctc aatcttcatc
    10261 ttgtcaatat cggtattttt tctttttacc atcttgatgg cttccgactg ttcgattgcc
    10321 ttgatatgaa aagagatatt gatgttatcg tctatatcca aaaactctgc aagcatacgg
    10381 tctgaaagct cacttgcaag gatttgaaaa tgacttgctg ctccgataaa tttcccaaac
    10441 ttaaaatacc ttgacggtgt aaagttaaat tcatcaggag caatatatgt ctttgtgctt
    10501 tctttcttct ttaagtcctt atatgaaaat tcaaaggtct tattgggatt taaaacatca
    10561 tgaagtatct tcagcctttc ttctccgttt agactttctg ctcttactcc catactttta
    10621 agacttgata atatatctat ctccagtctt tcaagttttg atgttgcctg ctctaaatta
    10681 tccgcttcca ctgtaaaggt tacatacttt gattttttca gtccgttatt tccctttaca
    10741 atctggcttt tcagcatttc tctaaactca aggcgaatat cgtcaaaacc gtccttttta
    10801 tccggtattt gaatggctga tttcatttct tcatttctgc caagctgatt aatatatgaa
    10861 aactctatgc tgacacttgg atcaaaggaa ttaagaaaat ttgcaaactg attaaaaatc
    10921 aaatctctat cttcttctaa ggcaagctga tagtttatat cctcaaaggc aatactctta
    10981 ttaaaatgct tttcatcaat ctgacatatc ccgcttttta agagtctaag atagggaatg
    11041 gtatcttcaa cagtgtatct tttcggttct ttcctaaaga taaggtcaag taatccgccc
    11101 ctatcttttt tagactttcc cttattttgc tttaagtcct gtttttgact tcttaacttc
    11161 ttttggtttt gttctaactt tagctgctga atttttcttt tgtctttcaa gataaacctc
    11221 ctttctcact cttttttgtg gctgataaaa tttgtgaagg taaatatact taaaatattt
    11281 ctcaaagcta agtccgtcct tttcaaaaag agttatgaaa aatataggga gagtggacac
    11341 aatgagaaag atgactgcta tatcatttgg aacgaccttt cgcataaata aatagattgg
    11401 tattccaata agtcctgcaa tcgtaaaacc tataagctgt cttttcgtca aattgaatgc
    11461 aacctttgtt tttaccttct ttaagtcttt tgggataggt acatacgcca taacttacct
    11521 cccatcttct tttccctttg aaagctcctc tatatgctca tatacggagc cgatttcttc
    11581 ctgaatactt gcaatctgtt catctgtact tctgttatat ctttcctgca ttagacaaaa
    11641 atcattgtgg cagcgaccga tgtcttttgt tctttcttcc aaatcattct ctttgatgtg
    11701 aagcctgatt ctatccatca ctgccaaaat acctgttcca actgctaccg ctatcaatac
    11761 tgtttttctt ttgttcatca tatctatcct ttcttttagt gtgcatttaa tacgcttttg
    11821 gccagtgttc cgctctttag catcattaac cccagcaaaa ccgcatatcc aagtatcgta
    11881 aaggtacttg tgtgtatatc tgttatttgt attgtcttaa ctaatactgc gtatattcca
    11941 agacaaacca ttaaaaagag tccttgtaat cctatggcaa ataagccttt gatatagttt
    12001 gttccgattt gtccccactc tttgtttccc attgtggcaa aaggaatggc tgaaacggat
    12061 gagtaaacat aaatctcaaa cattctgccg tataccacaa gcataatcac aatggaaatg
    12121 acctgtattg ccacctttat gagcgaggtt tcaaagagta tcatgacaag ctctccaaga
    12181 cctttatctt ttaagccttc taccatcgtt acaatctgat ctccagagat aacggcagag
    12241 gtgttaatta cccctgccgc tttatttacc atgtgctgtg ccacatcaaa gactgccata
    12301 gaaaactgaa aagcatggga cactaaccat acggcaatcc acatctttat gatgtatttg
    12361 aaaaattcaa aggtatccgt atcgtgcata ttgttctttt gcataaccat attgataagc
    12421 tcgatacaaa ggactgccgt tatgattagc cctgcaatgg ggataatgac agagtcgtta
    12481 atgcttttga taaaactaaa aacctgtcca ttccacccca tcggtgtctt tcccacatcc
    12541 gttgcaatcg caccaacttt atcgttgatg tcaagaaaca tggactctaa gtttgcttgg
    12601 ataccgccca gtagaagatc tttgaaaaac tcctctatct tgtcgaatat cccaaacatt
    12661 taatttctcc ttttcttctt acttgagtac atttgcaaga agcggaatca gctttaatcc
    12721 gataaggaca ataccgcctc ctgccataag ctgcttaatg ccctgagatt ttgcacccgg
    12781 attgtcatta ccataacctt ccatcaggtt aataacgccc catgctccaa gtcctgcacc
    12841 tactgccata actaaaatct ttaatacatt tactgcctgt gtaaaaaatt ccataattta
    12901 ttcctcctcg ttttcttctt tcttttcaat tttgttgtat gacttcacaa caaagttttt
    12961 gtaagtcttt ccatcttttt cacgcttctt aaagtatcca aagatatgga tcaaatcacc
    13021 tttttcaaag gcttttgctg tttctgactt ttcaccatag gctgcacaat tgatatattc
    13081 cttgcctttc ccatactttt ttacaagcgt aaagtttaca acttcaaccg tttctccctc
    13141 tttgtcaaaa cttgaaaaag ttggttctgc caataagttg gcattgatgt taatcatttc
    13201 ttgcttcatt aaaaatttct ccttttcttt tcaataaaaa aagcgatcgg agtttttctt
    13261 ttccaatcgc tgatactctt gctatttagt tttccttagt gggacttctt atccttacca
    13321 tctttcctcc tgattttgag taataaaaaa gcagcaaatc tatgttcttt agacttactg
    13381 cactcttgta ataaccgttt ctctatttaa ttttgctttc ccttttctct tgatatattc
    13441 ctcaatatca aaggcatttt tcttattaaa atcttcaagt aacttgtaat tcttatgctt
    13501 tgtaatatca aatttatctg ataaaaacgg tcttacacct ctaagctgaa agatacattt
    13561 actgccatcc ataaccgtta tctcatcttg actcatcagc tcttttcctg tcttttggta
    13621 attgagtcca taactattag cattggagcg tgtttcagaa gtgttatata gatctatcgt
    13681 ttcctttcca agcgtttctg atagctcttt taatgtggtc ttttcctttc cacctaaaaa
    13741 caatgtacta tcacagttgc ccacgattgt gtcagcatta tccttatata tcgcctttaa
    13801 ctgagattgt gcttgcaaaa taatgcttgc agatatttct cttgaacgga ttgtcgctat
    13861 taacttctca aactttggaa ttaagccgat atttgcaaac tcatcaagaa ggcatcttac
    13921 atgaacaggt aatcttcctc catactcatc atctgcctta tcacaaagta gattaaataa
    13981 ctgtgagtac atgatagata ccacaaagtt aaaagtatca tctgtatcag atataatgac
    14041 aaaaagtgct gtctttctat ctccaagagt atcaagctca agttcatctt ctttcatcaa
    14101 gtccctaagt tcctgaatat caaaaggagc aagtcttgca ccacatgaaa taagaataga
    14161 cttcgccgtt tttccagcag caagtttgta tttcttatat tgctttaccg caaagtgcgt
    14221 aggctctttc ttttccaatg cttcaaatag tctatcaatg ggattcatat atgtttcatc
    14281 atcttccctg acttctgaag catctatcat atccagtagt gtcgcaaagt tcttttcttc
    14341 tcttggagct tcataaaaaa tataacctat caaagccgta tagtagagtt tctcggcttt
    14401 cacccaaaaa tcctcacctg ccttttcccc ttcaccctta gtgtttgcaa tgattgtctg
    14461 cactaatttg aggatgtctt tttcacttct gagataggca aagggattgt acttcatact
    14521 ctttttgaag ttgatggtat ttaagatttt tatctcatag ccattatctt caagcatctt
    14581 gccacactca atgactatcg ttcctttagg atctgtaaca caatatgacg agtgcatttg
    14641 cattaggttt ggctttacat aaaatctcgt ctttccggag ccagaaccac caataacaag
    14701 tacattctta tttcttgcat actttggatt tgccggtctg ccattcatgg ttaatcgctc
    14761 tgtttgagta agcaagatat tgttttggaa cttttcatcc acatacggct ctatatcttt
    14821 tctcgttccc catcgggctg aaccatactc tttcccctgt ctgaactttt ttgcattttt
    14881 acctttggta tagacaataa atttaattaa aactgccact tccacgccca ttaaaatatc
    14941 tattggatga atgctcggaa taaagctcat ggtattaagc tctaatattc cttgaaatat
    15001 tttatctatt acatcgccac ctgtataggc tcttacatgg tgagagaaga tgtttccaac
    15061 atagaaaaat gcaagatagg gaatattctg cttgaaaaac tttgacttat cttgcacctt
    15121 aaataagcct ttgatgtctt ttagtatctt atctatcata ggctctgctc cttttgttta
    15181 ttcttgactt tatctttaga aagagcgttc tttgccattt ccttgaactt ctcaatattc
    15241 ttgtggatag attcttttct ttccgttttc ttttctgatt ccgaaagagc gtgtttaaag
    15301 gctttatcca tgactttcat gtcttttgcc tgaaagaata cggagtattt accgctttct
    15361 ttatctttca tcaccgaaaa ctttacccca taccgattaa gttccttttt cagttccttc
    15421 agctctgctt cttctaccgg aatttcttca agctgtccct ttttaaccat atcttttagc
    15481 tttacttcat ttccgttagc attaaccagc ttttccagtc ctccaagttt ttcagcctct
    15541 ttcatcagtt tctttaataa gttcagaatt agctttcctg ttactttagc agctttcact
    15601 tccatgttaa gcgtttttct tgcgatttct tcattgatca agttctctca cctccagtca
    15661 gtaatctttc tttattcctc tttaattttt cttcctgaat aactttcctg taattttctc
    15721 cgagtaccat cacaggaata cacatctcga taattcttga gtaaattctt tggtattcca
    15781 cactctccgt acagttttca atttggctgt atgaaagatt tgtggtaaag attgttggct
    15841 tatgctttaa gtacctgtta ttgacaatgt tatatacctg ctctttggca tagcttgtat
    15901 ctctttcaat tcctaaatca tctaagatga gaacggaagt gtttacaagg gattcgatat
    15961 atgcgttttt atcaatgtca aatcctcctt tttgcagttc gttgattatc tgtgaaaagt
    16021 ttctaatctt aacgcttatc tgatactgtt caatcagtgc attggcaata gagcaggcaa
    16081 gataggtctt tccgcttcca actgttccat agaacagaag tccgatattt tcctttttca
    16141 tcaattcata atcttttaca aaattctttg cgatgataag actctgattt tcttttccct
    16201 gatagttttc aaaggtatat gaccactgaa taatagatgt gaagcagata ctttttaatc
    16261 tctcgatttc aagctgcttt tgtctttctt tttcttttac ttctctatct ctatcgcatt
    16321 tacaagctgt cttaaatatc atctgctttc cgaaaaattc taatgctttt ccatcttttc
    16381 tttcatggca cactttacag taggcgtgtc cgtctttgat gtattctttt tcaggattga
    16441 agctgtattc cacatcttct atcatcactt tttctaattc tttaatcata aatgtactcc
    16501 cttgttatat tcctcccatg tagggatatt ggtttttttc ttacttccct gatctttata
    16561 aaaccaagaa aggattgttg ctttatggtc tttatatgtc tttccggtac tttgaagata
    16621 ggttgatagt ctttcaatgt agttatcaag ctctcctgcc attattattt gtaattctcc
    16681 tatgtcttcg tcctttaaaa agacattttg aaatgttcca agtccgcttt tcccaaaact
    16741 atattctctc ttactatact tactcttatt attctctata tagttagagt caacattttg
    16801 aacttcctga agttcatttt ctttacttct gaggttaaaa tctcttactt ctgaagttaa
    16861 gttttttgac ttctgaaagt cattttcttt taccgctatt atgctcataa aatctttaac
    16921 ataaatgaca ttcggcttac caagtccaag ccttactctt tcaatcagtc ctattccttt
    16981 tttgctgtct aactcgtcca atgtttttat ggcagtaggc tttgagatat ttcttcttct
    17041 cataatttct tcaacagtaa aatagataaa tactctgcct tccttgtcca cccagttatt
    17101 cttaaaggac attcctgtgc gtttcaaaag catggagtat agaataatgg cttcagcaga
    17161 cagtccctta aattcttctc cgtctactaa tatttcaggc actttcagaa agttaaatcg
    17221 ctctgcttct ctgttataga aatagtcaaa gtccatgcaa gatcacctcc ctccttaaaa
    17281 atttgcaaag aaaaagacga tagttttttc atctatcgcc tttggtaacc atttttatga
    17341 aattttttag attgatttta ttgcctcatt gataccttgt aaaaaagcta taacagttgc
    17401 accaaccatc ggtattccgt atggactaac taagaatcca ataatcaatg cttctattcc
    17461 gatggtaact tctttttgca gaaaagatgc aattgctcca aatatacaaa acatcatcag
    17521 caaatatagt agggctgttc cgataccaag tagaaatgtc agaaatgctg tgaggatact
    17581 taacaccaag ctaattggga ataagattat ttttattatc catctcataa tttcttattc
    17641 ctcactttca aaaacattct ttgtatctcc acacaccata tcaatgcaaa cattcacatc
    17701 catataattt tttaagactt tttttcgtcc tccctctccg tcttctacaa atacataatg
    17761 cttgtaaaac tgcttaaaat gcagtatttt cactatttca ctctttgtat caacgctatg
    17821 cactccacat gatgcgtttg aggaaataga tccaccggct ggactttctt caattcatat
    17881 cccaattctt ggtagagttt gatatcacgc gccatggttg ctacattgca ggagatatag
    17941 gcgatgcgat cggctcctgt ttgggcgctt gctttgataa agctttctgt caagcccttg
    18001 cgtggaggat caaccaagat aacggttggt tgaatcccat ctttaagcca attcttcata
    18061 gcattttcag ctgtgtcaca gacataatgg gcgtttgaaa tattgttcag ctgagcattt
    18121 tttttactat tctcaaccgc ttctggaatc agttcaacac cgtagacttc tttgacatgc
    18181 ttggcgactg ataaaccaat ggttccaata ccagaataag catcaataac cacgtcatct
    18241 ttttttaact ctgcaaagtc aatggctgtt tgatagagtt tctccgccat ttcagtattg
    18301 acttggtaaa aggctgggcc agcgatttgg aagtcatttc ccaacatctg gtccgtaata
    18361 tagtcttgac cataaagagt gcgccactcc ttaccaaaaa tcgcattggt attctggtcg
    18421 ttgatatttt gcatgacaga cacaatctct gggaactgct tgataacttg ttcaatcaat
    18481 tggtcaacac gaaaaacttt tggacgagtt gtcaccaaaa cgaccatgat ttgtcctgaa
    18541 tagtgaccac gacgcaccac aagattccga atcaatccag actgttcctt ttcgtcataa
    18601 ggttttaaat caaaacgacg gagcaggtct cgaagagcta ctacgacttg gtcaatgaca
    18661 ggatcctgga taaagaaatc ttcaaggggc atgaggttgt gcgaattctt acggaaaaat
    18721 cctgtttcca agacaccatt cactcgacga acgggcacct gcgccttatt gcgatacttg
    18781 actggatgtt ccataccaag cgtttcagca acttctacat ctgcaattcc agcaatcttg
    18841 tagagactgt ccttgacttg cttggtttta aacttgagct gttctggata agaaaggtgt
    18901 cctaaatccg cgattcctga acgcaggtaa gccaaatcta gatcttgatt acggtgtggt
    18961 gactggacaa ggtatttttc aacttttcca aagccaatct ttttattgac cttgaggaca
    19021 cgcatgagaa ttttttcact cggtaaagca ttctctacaa aaaagaccaa accatctacc
    19081 ttggcaactc ctgccccttc atgggtcaaa tcaacaattt caacttctac aatatcattt
    19141 ttctttaaca ttcttttctc tttctattgg ccgacaaaaa agacggcaac gttacggtta
    19201 ccatccatta taccatgaaa tttcttaaga accaaaactc ttgaagaagt tgacaagggc
    19261 ttgccagagg gagcttaaga agttaccacc gtcctctagc gccttatccg catcaaagtt
    19321 aaggttgata tttttaaaac tgtcgccagc ttgtgatacg atgctttgtt taaggtcatt
    19381 tagggtttta gtgaaatctg cattgctgag gatatcactc tttgagagat tcaaggcaaa
    19441 attgatgatg atattgatct ggtttcctgt tatgacctga tcaagtttgt aattttttaa
    19501 ggtatcttca acaatcttgc ggatatcttc ttctgtcaga tttcccttgc tttctttagc
    19561 tttggcgagt cctgacttga tatcagctag ggcaacgttt aatttattag catcatagcc
    19621 tgatttgtcc ttgttttcag cattgatatc tgacaaagtc tttagctctt cttgagccaa
    19681 atctttattg gcttgcggca ccttggctcc attagcttct agcgaatagt agatcccagc
    19741 caaagcactc tcacctgtaa ctggaatggg tgctgctaca gtgattttgg cgtgttccac
    19801 acccaaagtt acggctgcat ttcggtacat atcctgagtt accttagtga tgttttcagg
    19861 tgtttcaatc ttgacctcaa gtggcgattt gtcacctagc ttttgaatct tggctgatga
    19921 atacaactgt aagctagagt cattggccac attcatgatt ttagaataaa catcaggtgt
    19981 catggtcttg agttctttgg tatctgttga ggcattgtag cccagttttt taagagtttg
    20041 atttttttgg tcttcagata gggaagaacc taggacatat tcaggttgga cataggtttc
    20101 atcgataact ttttgaacat ctgttgctgc atagacgcta ttcatagctg ttactgccca
    20161 caagatcgca gcgctagtca gaaagagttt ctttctcata gggaatttcc tcctttactt
    20221 ctttagagta atatatctat cttaaagaaa acttataaca aaaacacctg gtctagccag
    20281 atgttgaaaa gagagtgaaa catttgatga tgtaaaggtt aagtcgtacc tgtctagaat
    20341 aataatagtt tcctccattt acatagagtt cagcaccgtg aaaaatggaa atgggatgaa
    20401 tataactata agtctttcca gtcgtattac caagcaaggg ggcaacagtc tcacgagagt
    20461 actgtttggc tagagccaag gtattttcct tgccattttg ggcgataaaa tcgatatagg
    20521 caggtccaaa attataggct tgaacagctg tccagatatc tacacccttc ttctgcgcca
    20581 gatagagatt gcctgtcaga gtttgaatgc cttgccgaat gctagaggca ttatcattga
    20641 tggtgttggt ggaaccactt gcagactcac tagactgcat aacatcgcct tcttttcctt
    20701 ttgtttcagt ataaatcata gcaagcacaa gctcttcgtt tgctggggtg tctttttcac
    20761 tcaatatttc tcgcaccatg ggttgatagg tcatgacttg tttgacatct tgatgaacgc
    20821 ggtaagcttt atagccagca aaaaggaaga ctgctagtac aagcactctt cgaattcgtt
    20881 taaacattat ttactttgga tatcctcgat atttttgatt aagatagagt aggttccatt
    20941 ttcgttttgg ataaactcaa cagactcggc gtcttgatag acgttattgg gaacgatgag
    21001 ctcaattcca tttgataagg agagtttttg gttttcaaat ttctttaatt ggcgactggc
    21061 atcaatttca tcaaattgaa caggttctgg tacggcttct ttgacttggt caataaagct
    21121 caaacgagcc gtcagattgt tgtcaaaaag gtcattagcc aatttctcag gtgacaattc
    21181 attgctttct tctaggttgt tgaaaatcgc tgatttgacc ttggattgaa attgaaaatc
    21241 atctgtgtta aaagattcag caattctctg ggctgttttt tccagttcct tgatagattt
    21301 tttaggagaa atcttaggag cgacagcaag aagattatct gaaaaatagt tcaaaaaagt
    21361 cccgttgtac ttgattcgtt tttcaatcag gtgatacttg cgactctgaa gattgaccac
    21421 caaggcctcg tcagcacccg ttccaaatcc aggcaggtta ttctgagtca gcttgattgg
    21481 attatcaact tctcctccga ggtgggtcaa ggtctcccgc agggcaattc gcaagaaagc
    21541 gaaatgttct acaccttctt tagaaaattg aacaaaaatc aagtcattgg tcttgagatt
    21601 ttcagaaatg ctaaactcct ctttccagag attagccagc gttactgatg tctccaacaa
    21661 atcgtctgta atatgattga agaagggatt ttcttcttcg aaaatcccag tcttggcttc
    21721 atctgaatac acatgttcaa tttttttacg taggtattct tcgatttttg gagtaatatt
    21781 gagaaactta tctgctaaga acagctcggt atcatccgga ctgaactggt gaataatggc
    21841 tttcttaata taaatgtcca taaaagtttt attcctcgta taatgggaag gcatctgtca
    21901 attctttgac tgcacttctc acttcttcta atacagcctc attttctgaa ttcttaaggg
    21961 ttttaatgat gagttcagcc actttgcgac tttcttcttc accaaattca cgtgcagtaa
    22021 tagctgctgc tccgatacga atcccacttg tcttgaatgg tgacaaggtt tcgtaaggga
    22081 ttgaattttt atttagggta atattgactt catccagcaa gttttgagca acttttccgt
    22141 tttctacaac cttagtcaca tcaacaagga agagatggtt ttcagttcca cctgaaataa
    22201 tacggaaatc agggtcttgc aagaagacat ctgccatagc cttgctgttc ttaattacat
    22261 tggcagcata ttccttgaag gctggatcca aaacttcttt gaaggaaact gccttagccg
    22321 ccacaacatg ctctaaagga ccgccctgaa tacctgggaa aatagctgaa ttgatttttt
    22381 tagcaagttc ttcgtcattg gtcaaaatca aaccaccacg aggtccacga agggttttgt
    22441 gggtcgttgt tgttgtgata tgagcgtatg gaactgggct tggatgaagg ccagccgcaa
    22501 ccaagccagc gatatgggcc atgtccacca tgagcttcgc accgacagca tctgcgattt
    22561 cacggaattt tgaaaaatcg ataatttgag aataggctga agcaccagct acaatcagtt
    22621 ttggttttac ttcttgggct tgtttcaaga tagcatcaaa gtctaagagt tccgttttag
    22681 gatcaacact ataagaaaca aagttgtagg tttgaccaga gaagctaaca ggagccccat
    22741 gagtcaaatg accacctgat gccaaatcca ttcccataac cgtatcacct ggctcaatca
    22801 aggacatgta agccgcacag ttagcttggc ttcctgaatg tggttgaaca ttggcaaatt
    22861 tagcaccgaa aatttctttt gcgcgttcaa tagcaagagt ctctacaacg tctactacat
    22921 cagttccacc ataataacgg cgtcctgggt aaccctcggc atatttattt gtcaagatag
    22981 acccttgagc tgccataaca gccttggaaa ctacgttttc cgaagcaatt aactcgatat
    23041 tattttgttg gcgttcttct tctttggcaa tagcattcca gagatcagca tcatatgctt
    23101 taaaatcatc tttgtcaaaa atcataggtc ttctccttta ttgtgtgact agtccattag
    23161 tttgatttta caataagaaa atcaaactaa cagatgcgaa taaaccgttt ctgcatttta
    23221 tcacaagtat agccaacttt ttcataaaat gcatgagcac ccagacgatg attggcagaa
    23281 tttaagcgga taaacccata accacatctt tttgcttctt cttccaaccc ttgtagtaaa
    23341 cttttaccaa taccttgacc ttgcgcttga ggtgaaactg ctaaagctaa gatattaaat
    23401 cctgctttgg aatagagtga ttcgtaaact tcagcgtgga catatccaag taagacatga
    23461 ttagctgcat cctcatagcc aagtaggaaa tgatgggaat cctgagacag tctagctagt
    23521 tggctagccg tttcctctgg actaaaagta taacccaaag cctcttggtt gatgtcacat
    23581 atcgctttca catctgtttc ttgcaaatct cttagcattt caagcctcct caaaagaaat
    23641 ctctggcaac cgagcaagaa tatcttctcg tttaattgcg ccttggcgta agattttcac
    23701 cttgtctcca gacaaatcca caatagttga atcctgtcca gttagaaaag catcgtcttc
    23761 cagacccaga acctcttggt caaaatcctt cagaatttgt tcaaaggtta caccacttgc
    23821 ctgacctgag atattggcag acggcccaat caagggacct gtctctcgaa ttaaatccag
    23881 tgtgataggg tgactgggca tccgaaatcc aatagttgca aggtcagaat ttacccaata
    23941 gggaactcgg tcattggctt cgagaataat ggtcaaggga cctggcaaaa aggtctctac
    24001 aagtttttgt agataagctg gctgattctt tgaaaagtgc aagatgtcct cgaaagaggc
    24061 gatattgaga ttgagtgcct tatctctagg acgacgtttg agttggtaaa catggtcaac
    24121 tgctttttca tctaaggcct tggaaaaaag accataaaca gtctctgtag gtagaacgac
    24181 agctccaccc ttttccaact cttgtctaat cctgtccatc atcaaccaca accatcctat
    24241 tttgaccaaa ttggtctttg agtgttcgaa ctcttttttc aggaagatgt tttctaaaaa
    24301 gttcgggaac acattgacct tgcttgtatc caatttcaag gtaaatctta ccactatctt
    24361 tgagatagtc tgttgcatct tccgcaattc tacggtaaat agctaggcca tcctcgtctg
    24421 caaagagagc tagatgaggc tccgaataca agacattcaa gcctacctct gactcatctt
    24481 cacgagagat atagggtgga ttggaaacaa ttatatcata tttttcagaa atttctgtaa
    24541 aacagtcaga tttttttaaa aatatttgaa gattttgatt tttagcattt tctctagcta
    24601 aatctaaggc ctcttgagaa atatctgctg ctgtcactga ccaatctggt ctattttttg
    24661 ctagagcgag agcaatagct ccactacctg ttccaatatc cagaactgag agattcgtct
    24721 caagattttc agttagaata agctccacta actcctctgt ttctggacga ggaatcaaaa
    24781 cccgttcatc cacctttaaa tgcattccat aaaaatctgc ctgtccaatg atgtactgag
    24841 ctggcttgtg agctgctagt tgctggtaaa tatcttctac aaattgtttt tcttcctctg
    24901 ttgtcacctc ctgctggagg gcaaaaataa agtctgtaaa agatagattt ttcagactac
    24961 gatagacaaa agagaggctt tccgcttcct ctccttgtct tatcaactct tcttcaaaat
    25021 ttgaaaataa ttgagctaat ttcattattt gtttaattct tctagttttt gtgtttggtc
    25081 ataaagcacc aaggcatcca caacttcgtc caatttacca gacaaaatcg tatctagttt
    25141 ttggagggtc aagccgatac ggtggtctgt gacacggttt tgtgggaagt tataagttcg
    25201 gatccgttct gaacggtcac cagtaccgat tgtcgactta cgctcagcgt cttgttcatc
    25261 ctgagcaatc tgagcaaagt ggtcagcgac gcgtgcacgg ataatcttca tagccttctc
    25321 gcggttcttc tgctgggtac gttcttcctg catctcaacc ttgatattgg ttggcaagtg
    25381 aacgatacga acggcagtcg caaccttatt gacgttctgt ccaccagcac cagaggcgtg
    25441 atagatgtcg acacgaaggt cttttggatc aatgtcgtat tcaacctctt caacttctgg
    25501 cataacaaga actgtcgctg tcgaagtatg aacacggcct tggctttctg tcacaggaac
    25561 acgttgcaca cggtgggcac ctgattcata cttaagctta gagtatacag actgacctga
    25621 aaccatagca accacttctt taaaaccacc gacaccattc atagaggctt ccatgacttc
    25681 aaagcgccaa ccttgggctt ccgcatactt ttggtacata gttagcaaat ctccagcgaa
    25741 aagtgccgct tcgtctccac cagctgctcc acggatttca aggatgatat tcttgtcatc
    25801 gtttggatcc tttggaagga gcaaaatttt cagtttttct tcatattctt ctttttcagc
    25861 cttggcatct ttgagttctt gcttggccat ttcttccaag tccgcatctc cgcctgattc
    25921 cttaatcatc tcttcggcat cgacgatatt ttgaaggact tgtttatact cacggtaggc
    25981 tattacggtg tcacgattgg aagcttcttc ttttgaaagc tccataaaac gcttggtgtc
    26041 tgaaacgaca tcagggtcac tcagcaattc tcctagttct tcataacggt cttctacagc
    26101 ttgtagttga tcatagatgt tcattttttc tccttatttc tcaattgtta aatcatagat
    26161 tgctactact tcattctcgg atatttcccc agtttcttta aatccataac tgaggtaaca
    26221 aaatcttgcc tgttcatttt ctggttcata agacaaccaa agtttattgc ttaaacctgc
    26281 tggcgctgtt cgaacatagt ctagtacttt atccataatt ggtttaaaat atccttgatt
    26341 ttgaaaattc ttatcaatca taaaacgaaa tagtaaataa tttccactac taattccgat
    26401 ctttttatca taagctatca tcacaaaacc tataattgca tcattatcat aaactgccaa
    26461 tgtagctaca aaatctccat ttttagtgta gacgtatgct tcagctaaac taattgcgtt
    26521 ggttgcaatg aattgttttt gatattcctt gacatccaaa tttaaaacat caaaataatt
    26581 ttccattgta acatctctta gttcaattgt catagttttg ctccttgtta gaggttatca
    26641 ttggcgtaaa ataatgttta cggcaaactg agatataggt ttcgttacca ccaatctgga
    26701 tctgttctcc atcgtaaacg ggcagtccat cctgtgttcg caacaccatg gtcgcctttt
    26761 tcttgcaata ctgacagatg gtcttgattt cgtcaatctt gtctgctaaa agcaagagat
    26821 atttggaacc ttcgaacaat tcattgcgaa agtcattttt caagccaaaa gccatgacgg
    26881 gtatgtctaa ctcgtccaca acacgagcta ggtcgtaaac atggtggcgt ttaagaaact
    26941 gggcttcatc gaccaaaaca cagtaaggtt tttctggtag gtctcggata tagccaaaga
    27001 tatccgttgt ttcctcaatc gcaagggcag ggcgtttcat gccaattcga ctcgacacat
    27061 agccaacacc gtcacgcgta tccagagccg aggtcataat gacaacacct tttccttgct
    27121 cctcgtagtt ataggccact ttgagaatct caatcgtttt accagagttc atggtcccat
    27181 aacgatagta caactgtgcc atgtttcttg cttcacgtcc atttctaaat ttttgctaca
    27241 ttctagtata tcataatttt cttaagcttt aaacggcaaa atgtggtaaa atggaagaaa
    27301 tcaaaactag tggaggaagc tattatgcca tttgtacgca tcgatttatt tgaaggacgc
    27361 acgctcgagc aaaagaaagc tcttgctaag gaagtaacgg aagcagttgt ccgcaacact
    27421 ggagcccctc aatctgctgt ccatgtcatc atcaacgaca tgccagaagg aacttacttc
    27481 ccacaagggg aaatgcgtac taaataagct agcttaagca gaattgctta ggctttttca
    27541 atctccaagt agcattcatt gaagaaatat cctaaatttg ttacaatttg aaaagaaact
    27601 tggagaattt ccaagaaaag agctattaat taaaggaaac attatgatta cacgtgaatt
    27661 tgataccatc gctgctatct ctactccact aggtgaaggg gctattggta ttgtccgcct
    27721 gagcggaaca gacagttttg ctattgcgca aaagattttt aaaggaaaag acttgaacaa
    27781 ggttgccagc cacactctca actacggtca cattattgat cctctgactg gtaaagtcat
    27841 ggacgaggtt atggttgggg ctatgaagtc tccaaagacc ttcactcgtg aggatattat
    27901 cgagattaac acccacggtg ggattgcggt gaccaatgaa attctccagc tagctattcg
    27961 tgaaggggct cggttggcag aacctggtga atttaccaaa cgtgcttttt taaacggtcg
    28021 cgtagacttg acacaggcag aggctgtgat ggatatcatc cgtgccaaga ctgacaaggc
    28081 catgaacatt gcggtcaaac aattagacgg ctccctttct gacctcatta acaatacccg
    28141 tcaagaaatc ctcaatacac ttgcccaagt tgaggtcaat atcgactatc ctgaatatga
    28201 tgatgttgag gaagctacta ctgccgttgt tcgtgagaag actatggagt ttgagcaatt
    28261 gctaaccaat cttcttagaa cagcccgtcg cggcaaaatc cttcgtgaag gaatttcaac
    28321 agctatcatc ggacgtccca acgttgggaa atccagcctt ctcaacaacc tcttgcgtga
    28381 ggacaaggct atcgtaacag atatcgctgg gacaacacga gatgtcatcg aagagtacgt
    28441 caacatcaat ggtgtacctc tcaaattgat tgatacagcc ggtattcgtg aaacagatga
    28501 catagtggaa caaatcggtg ttgagcgttc gaaaaaagcc ctcaaggaag ccgacttggt
    28561 tctactagtg ctaaatgcca gtgaaccact gactgcgcaa gacagacaac ttcttgaaat
    28621 tagccaagat accaatcgca ttattctact taataaaacc gacctgccag aaacgattga
    28681 aacttcgaaa ctacctgaag acgttatccg tatttcagtc cttaaaaacc aaaacatcga
    28741 caagattgaa gagcgaatca acaacctctt ctttgaaaat gctggcttgg tcgagcaaga
    28801 tgctacctac ttgtcaaacg cccgtcacat ttccctgatt gaaaaagcag ttgaaagcct
    28861 acaagccgtt aatcaaggtc ttgagctggg gatgccagtt gatttgcttc aagttgactt
    28921 gactcgtact tgggaaatcc tcggagaaat cactggggat gctgctccag atgaacttat
    28981 tacccaactc tttagccaat tctgtttagg aaaataagaa aaatccatga tccttcattc
    29041 ggtcatggat tttattgtct ttattagtaa tctggtctta agacccctgt tacagttgcc
    29101 ttagttgctt cgtagtcgcc atctacgaca accttgataa tgcgtttggc atcttcttct
    29161 ggtgctggaa caagaggtag acgagtgggt ccagcttcaa atcccatata gttaagaatt
    29221 gccttaactg gagcaggact tggataagag aagagagcat taaccttagg aatgaattta
    29281 cgctgaattg ctgcggcttt cttcatatcg ctttctgcaa tggcagtaaa catctcgtgc
    29341 atttcatccc catttgtatg agaggcaaca gaaataaccc catccgcccc aaggttcatg
    29401 gcatggaaag catctccatc ctcacctgta taaatcaaga actcttcagg cttgtgctca
    29461 atcaagtaag ccatattagc caagctagta cattctttga caccgataat atttggatgg
    29521 tcagccaagc gaagcatggt ttctggagtc aattcgacaa ctacacgccc tggaatgtta
    29581 tagataataa ttggtaggtc agaagcatct gcaatagtct taaagtgctg atacatccct
    29641 tcttgagaag gtttgttgta gtaaggaaca atagcaagcc cagctgcgaa accaccaaat
    29701 tccgctactt ctttgacaaa ctcaatagaa tcacgcgtat cattagtacc tacacccgca
    29761 atcaaaggaa cgcgtccatt gacaaccttt tgtacagccg caaacaactc caactcctca
    29821 tcgtgggtca aagttggact ctcagcagtc gttcctgcga gaagaattcc atccgtatga
    29881 tgggccaata aatgctcaat caaggctgga atagcatcaa agttaatgga accatcctca
    29941 tggaaggggg taataaaggc tgtaatgatt ttacattctt ttaaatcttg ataagacacg
    30001 aaaacacctc tctatttcaa agaaggagtt catctgaact cctaaacgat atgactattt
    30061 taattcaaat ttcaattcgg ctgttggacg aaccaatcca cgttcatgaa gagtttcagc
    30121 aatctgaact gagttccaag cagcaccttt gagaaggtta tctgaaacaa cccacatgtg
    30181 aattcctttt tctgcatcca agtctttacg gatacgacca acaaaggtat cacgcgaacc
    30241 aactgcattg atagcttgag gatagatttg atgagctaca tcatcttcaa gaacagcacc
    30301 tgggaaggct gcgatagctg cttttacttc ttcgattgga gccacttctt ttgtttcgat
    30361 ataaacagac tcagagtgag ctgacaagac tggaatacgc acacatgttg cagatactgc
    30421 aatgctatca tcttccataa ttttcttagt ttccttggtc atcttcatct cttcgtacgt
    30481 gtaatcatta tcagtgaaaa catcaatttg tggaagagcg ttaaaggcga taggataatg
    30541 tttcttgtca ccacctgaag gcaaaatttc cgcatgcaaa tcacatggtt tcacaccatc
    30601 attcaagact tcacgaagtt cacgttgtgt ctcaagaatt gctcccatac cagcacctga
    30661 aacggcttga taagttgaaa caatgatacg gtccaagccc catttttggc gaaccggctc
    30721 aagagccacc atcatttgga ttgttgaaca attagggcag gcaatgattc cgttgtgagc
    30781 atcaagtgca tgagcattga cctctggaac aaccaaagga acatctggat tttgacggaa
    30841 ataagatgta ttatctacta ctaccacgcc agcttttact gcgtatggtg catacttagc
    30901 tgatgtagaa ctacctgctg aaaagagagc aatatcaact ccttcaaaag ctgtttcagt
    30961 cgtttcttca attgtaatat cttgatcttt aaatttcaat gacttacctg ctgaacgtgc
    31021 agaagcaagg taacggattt tatcgattgg aagtgttgat tcttccaaca tttttatcat
    31081 ctgagcaccg acagcacctg tcgcgccgac tacagcaact gtatatccca taaataacct
    31141 ctttcggaat tttctaaaaa tttctataat agaagtatta tactactttt tccatgaatt
    31201 gcaaagcttt ttcatcattt tttggaaaat aaaaatccca gtcgctagac tagggactaa
    31261 gaggcatctt catgtgatga gcaggttcac acaactcatc aaggtccgct cctgcgttat
    31321 gacctcctta tgctcaatag tagtccgaag actacctatc gactcatcgc atattctata
    31381 ttactagaga tacttgattt tgtcaataag aaattttttc gatcgagtat aacaaaaaac
    31441 tctcgtattc aagagtttcc ctatacatat catgctaatt gccgggattg aaccggcgac
    31501 ctcatcctta ccatggatgc gctctgccaa ctgagctaaa tcagcttact taagaagtat
    31561 actatattca gaaaaacttg tcaagtttcc ttagaaattt tccataggaa aaagccaggt
    31621 aagaactacc tagcttatct tcttctattt acttaaatca attcgacgac caattttacc
    31681 aataataatc gctccaataa tcaatgaagc aaattcaccg attcctgttg taaaccaagt
    31741 aaggaagaat ggtaattctg ctacaatatt taactctgca gcgatagtaa acatggaaat
    31801 tgaaaagagg attgaaaaga agaaatgatc ttttcgaatc aatccattaa agaggtaatc
    31861 cttgctatat tttgcaaaaa gccaaacacc taaactgagg aatactaagg ttgaaccacc
    31921 accaacaaag acatctagca gtccgaagct aaagaaatta gcaatcatac aaccgatggt
    31981 aactccgatg atgtacttag gattgtaaaa agccataaag ttcatcattt ctgaaatacg
    32041 aaactgataa gcaccatagc tgatggcatt taggggcggt gtgacagtca aaacgacgta
    32101 gatagcagcg acgattgcaa tatctgcaac atcacgaata gttaattttt tcatcttttc
    32161 tcctttggcg gttatccgcg tgtaatatgc ttggtgaaag aagctaagca ccaagggttg
    32221 attcattcaa ccttactagt atagcacaat agcctgcttt atgctatact taaagcatga
    32281 aaaaacctat tcaaaaattt tttaacaatg aaatcttagc ctatctcttt tttggccttg
    32341 cgacaactct agtttcgatt ctctcacgac tagtcattta tcaactaagt catcaggaac
    32401 tcctggctac tgccctagca aatattatcg gtatcctatt tgcctttatc acaaatgata
    32461 cgattgtatt taagcaaaaa aagaaaaata gacttatccg tttagtgaaa ttttctcttg
    32521 ctcgcctttc tacttttctg ttagacttgt ttttaacttt tctctttgta acccaatttc
    32581 ctcacattat agggcaattc gtaactgaaa acattgataa gataaatgct attgaaacaa
    32641 taattgcaca aatattcatt attatcatca attatatctt gagcaaggcc tatattttta
    32701 gaaaataatg ctccatttat gagcctttta attgccttct ataatgattt aggatacaat
    32761 gaaacacgaa acattgaaag gaaaacagta tgttaaaaaa tctaaaatcg ttcttgcttc
    32821 gaggaaatgt tattgacctt gctgtcggtg ttgtcattgc ctctgctttt ggtgctatcg
    32881 ttacttcact tgtaaacgac attatcactc ctcttatttt aaatcccgct ttgaaagctg
    32941 ctaaagttga acgtatcgct caactttctt ggcatggagt cggctatggt aacttcttaa
    33001 gtgctattat caattttatc tttgtgggta ccgccctctt ctttattatc aagggcattg
    33061 aaaaagcaca gaaactgact ggcataaaga aagaaaaaac tgccgaaaaa aaaccaaccg
    33121 aattggaagt ccttcaagaa ataaaagctc tccttgagaa aaaataatcg attaaaagga
    33181 tctagcgcaa agctaaatcc ttttttcttt actctttggg taacttgcct gctttttcaa
    33241 gcattttttt gataagataa ggcatcttaa cattctcccg cccttttttc tcaatcagtt
    33301 ttttcacaaa ttctggcatt tgtaaatctt cagattcagc taaaatgttt ttcgtctcgt
    33361 ctgaaggaac taactcatca aaggtctctt cttctgggag aaattcctta aactcttgat
    33421 tttcattgac tctaactgta ttgaccaaag catcaatcaa acgagaatct gtatttggca
    33481 ttggtggacg atggtagttt accccaaatt cctggcataa gtcataacat tctacatcat
    33541 tgtcaaacaa gacctcaata tgctcactga tgaaactaat aggtacaaaa atataatggt
    33601 ctggatgtgc tgtctgttct ctgagatact ccaaaacatc tggtttaatc catggaatac
    33661 caatatcact ctcactctgc caagtgttgg tatattgttc tgaactcaag cccagttttt
    33721 caacgactag cttgctattt tcgaaaattt ggtctatata aggatcacca aagtccaagg
    33781 caaaaatagg cacactatgg gctgaaaaga tgattttaaa gctgtcttgc tttacttctt
    33841 cttttaaaat cttagcaatt tcatctgccc aatagtttaa gagcgcttct tcctgatacc
    33901 agtccttaat gaccaaaaat tgaatttgtt tgctttctaa aaatttttca tagcccatga
    33961 cagagtagaa agaataatgg ggctccaaaa tcaagcaaat acactgttca attccgtctg
    34021 cttccatttg accgatcaca tctggaataa agggactgga aaacttatta gcaaagtaga
    34081 cactgtattc attccccagc ctagcttcta ccaaggcaac ctcttgatgg gtaatttttt
    34141 gcagaggcgt gcctccaatt cgtacataat tatcatagag agtctgaatc tcgtggtctt
    34201 ggggtctcac cccacgacga atatttgtga aaaaatcagc tacaccttca aaggtagtct
    34261 cttctggtga accgaaggtc atcattaaaa ttgctttttt catgactgct tccttgtgat
    34321 gtttttatca agtttatttt atcattaatt catcgataag taaacgctaa catagggaca
    34381 ttctcaatct tctgtctttt gtttttctct tctttctatg atacaatgga aaaaataaat
    34441 tcaaaaggag ttttttatga cttatccaaa tctcttggac cgcttcttaa cctacgttaa
    34501 ggtcaacacg cgctctgatg aacactctac tactactcca agtacacaga gtcaggttga
    34561 cttcgcaaca aatgtcctaa ttcctgaaat gaaacgtgtt ggactgcaaa atgtttacta
    34621 tctaccgaat ggttttgcta ttggaacctt gccagccaac gatccgtctt taacacgtaa
    34681 gattggtttt atatcgcaca tggatactgc tgattttaat gctgaaggag tcaatccaca
    34741 ggtaattgaa aactacgatg gtggtgtgat tgaactaggg aattctggtt tcaaactcga
    34801 tccagctgac ttcaagagtc ttgaaaaata tccaggacaa acgctcatca caacagatgg
    34861 aacaagcttg ctaggtgctg atgacaagtc aggaattgct gaaattatga cagccattga
    34921 atatctaact gctcatcctg aaattaagca ctgtgagatt cgtgttggtt ttggtccaga
    34981 tgaagaaatc ggtgttggtg ccaataaatt tgatgcagaa gattttgatg tggattttgc
    35041 ctacactgtt gatggtggtc cactaggtga acttcagtac gagactttct cagccgctgg
    35101 tgctgaattg catttccaag gtcgtaatgt ccaccctggt actgccaaag ggcagatggt
    35161 caatgccctt cagctagcaa ttgattttca taatcaactt ccagaaaatg accgacctga
    35221 gttaactgaa ggttaccaag gtttttacca tctaatggat gtgacaggta gtgttgagga
    35281 ggcgcgtgca agctacatca ttcgtgattt tgaaaaagat gcctttgaag cgcgtaaagc
    35341 atccatgcaa tctatcgctg ataagatgaa tgaagaactt gggagcgacc gtgtcactct
    35401 caacttgaca gaccagtact acaatatgaa agaagtcatt gaaaaagata tgactccaat
    35461 taccattgct aaagccgtta tggaagatct aggtatcacg cctattatcg aaccaatccg
    35521 gggtggaaca gacggctcta agatttcctt tatgggaatc ccaactccga atatctttgc
    35581 aggtggcgaa aatatgcacg gacgttttga atacgttagc cttcagacta tggaacgtgc
    35641 agttgatacc atcattggca tcgtagctta taaaggctaa aaagacgagg tagctcagct
    35701 acttcgcctt tctttttatt ctactggttt ttcttgattt ccagtagttg tagaagattc
    35761 tgttgtttca ttttctgaag ttgattcagc aggtttagaa tctcttgtat tgcttggttt
    35821 gttttcgtcg ctagcagttt caatgttaga ttctgcagtt gcgtttggtt ggttctcagc
    35881 actggtgtta tcaccatttg cttcagcatt tcttgctgga cttgtttctt cacttgcgct
    35941 agcttttgac tggatttgat gattcaaaac tagaatagct tttgtcgatt caagtaaagc
    36001 tgttttgtct ttactcttag cagaaagttg atctaataat gcatccacct tatcaaagtc
    36061 cgcatcagat ccattattac tttctaaata agagtgaagc gacatgagaa tatcgtagag
    36121 tttttgatag agtacaagtg tctgaggatc ttgctcagca ttttcctttt cttgttgaag
    36181 ggcgctagcg atacgagtca agacatcttt tacctgactg tttacttcat ccaagtctgc
    36241 atcagccttg tttgtggcag cttttagatt ttctacttct tctgccaagg attgtctgat
    36301 tccttcttca tggatttgtt ccaagagttg atttgccttg ctcaaaagac tttctacttc
    36361 ttccttgcta tctgtcgcag attattggtt gctatctacc atgtactcct aaaacaggag
    36421 agttataatc caagattaca aggccttaca gaaataagaa atccagataa gacaatgttc
    36481 gtccaagacg ctattcgctt cgcacagcag cacggattca atatgcttta attttaaagt
    36541 ttaggtgtca agacctcttt ttagtgtgcc caaaatttag agaagtaatc aatcaactaa
    36601 cttttatttt tttcaaactt tcagtaaact gacctaaagc taactcaatc tgtctttgta
    36661 gatgcttctg ctatcagcta gaagttgatc tacttttgcc aagactgcct tctcatcaaa
    36721 agttccaggt tgatagttgg attgcaggga tggaatcttg tttttcaaag ccgcttcata
    36781 tcccttagtt tgaaccttga tgtagtgatt gtggtcgcca tgaggaatca caaaaccttc
    36841 tgaatcttca cttataattc gattggcatc aaaaccatga ccatcttctt cctcatgatg
    36901 gacatgtagt gacggattac ttaatacaga actagaagaa cttcctacct cttccgtgtt
    36961 agagtgtgat gggggattgt taagagatga cttaggaata tagtgatagt gatccccatg
    37021 tcttactata taagcatcac ctgtatctct gacaatatca ttagggttaa agacatatgt
    37081 ggctgctaat tcacctgccg acaagtcact ctcaggaatg aaatgatagt gaccaccatg
    37141 tggtactata gtagattgaa atagaatatg agcaaattga taaggggatt ttaaagtaat
    37201 ttctaacaat gatttagaaa ctatgatgtg ctattctaaa ttcaactcac tatatataac
    37261 catcatcggt agtataacgt ccctgtaatt ttgctacaga tacttctgca ctagctcctt
    37321 tatcgtcttt accatgttct tgtttttggc gattgatttc atcttttgtt cgtacatttt
    37381 ctgcatgagc ttgatcttta aggtaaacat aatactttcc atctacctta ataatatatc
    37441 ctcccttaac ctaactgacg atatcttgat ctttcggctg atagttgggg gctttcatta
    37501 atagctcttc actaaagagc gcatcaaaag gaactttacc attatagtag tgataatgat
    37561 cgccatgaga agttacataa ccttgatctg taatcttaat aacaatttgt tttgcttgaa
    37621 ttccttcttt ttgactaacc tagtctggag tcaaattttc agtcttctta gtgtctttat
    37681 tactgtttac atatgaaaca cgatttttat ctgtattggc ctgttagcta tgttggttca
    37741 gagcataaac acacagactt aaggaaagga taacaacaga tccagctgct atatatttct
    37801 ttttaaattt cataattacc tcatttctat aattatttat atgatgtctt cattattaaa
    37861 tgattaaata aattaattaa ccaattaatt aactagtaaa tattccacct ctttttaagt
    37921 tgtatgtcaa gaaattttat atattaataa taaaatgaaa ttctcccaaa gtcagagttt
    37981 tatttctaac ttttgagaga acttcatttt tgattcagac tttttctact gctattcctt
    38041 acgctatgag atcagataaa ttctttttta tcacttctcc acttggcaat cttaattcaa
    38101 tcgttccatc catattgaat ataacactat ctaagcctaa tccgtaacta gctgtaaatt
    38161 tttctaattt ttcttgtaca ggatctactg ctggagcttc ctctaatgct ggatctaaca
    38221 tagggtcact ccccacattc ccttctggat tcaacattcc attatccgtt gagttttctg
    38281 gttttacagg tttttcgttt ggtgcctctg gtaaagaatc tgctggttta ttttctgttg
    38341 gttggttctc aactgttcca gtagatactt ttccattttc agatggttta ttttcaccat
    38401 ttccttgagg tgcttctcct gtaaaatctg ccatattctt tttaatgact tctcccgatg
    38461 gtaaatataa ttcaattgtt ccgtccatat taaacaagac attttctagc ttcatcccat
    38521 aactttcagc aaattttgct actttttctt gtacaggatc cactgtagga acttcttcta
    38581 acgttgaatt actagtacta ttcccagttt cagaaagttt ttctttttct accttctcac
    38641 tagtctttgg ttcttctacc ttttcatcaa gttttgagtt ttcttgtgct ttattccttt
    38701 taaattgtgg tagaatactt ggtttatcag tttgattttc tttttccaag ataggtactt
    38761 ccacaatata agtcgattga ttgtccaaat aagcatttgc catgaaggtt acaggaattt
    38821 tatttccggc cgttctggtt gttccttggt ttaatttcgg aatcggtaat ttgatttcac
    38881 caactttata gttattttct aaataagcat ttccatgaaa ttcatcaaac actctgacta
    38941 aagcatcagt tcctttaggc actgcaaatt gagggttcac tcttaaataa gtatcccctg
    39001 catggaaagg atagaaaatc gtttgactgg ccattttgta agctaaagag gttggaactg
    39061 taaatgtacc atcataactt acttctggat aatcttttga agcgatagta tacttaaatg
    39121 tttgtcctgg taaataaggt tgatctaatt caaagtttgc aatattccct actccttctc
    39181 caaatacttt accagatact ttctccaata cttttccatc tggtgttatt aattttacta
    39241 gcatattgat acctaatttt ttctccaatt caggcggaaa actaaaagaa acgcgttttt
    39301 gaccattggc tagagtaaag ttttgattat taaacgtact attttttaac aaattaacaa
    39361 cattcgttaa ttcttctcca gtataaactt tattcccttc ttttttagca actccttctt
    39421 cgggtttaaa cagttcatag ttactgtgag aatgaccaat tccaaccggt ttatgttcat
    39481 caatcggatc tgcatgatgg tgatctccat gcggataaat aatcgcattt ttttctttat
    39541 tcacgacaat actttcacgt ttgacaccat attgtttcat aatgccagca attttttctt
    39601 cgattttttt atctaaatct ttcatttctt tggcattact tggataatcc tgttcatgag
    39661 atgacaaaga atctaatcca ttatgactag ttttaacttc ctctaaatgt ttttgcgcag
    39721 ccttaatttg ctcttctgtc aagtccttct tgaagaaata atgattgtgg tctccgtgac
    39781 tcatgacaaa acctgattca tcttcagcga taatacgatt agcatcaaat ccgtatccat
    39841 cttcttcatg tttctcatgt gaagttcctg gattgattgg aagagatgga gaaggtgttg
    39901 ctagactatt gtttggaaga gtcggttgcc caatttgatt tgattttgga atgtaatgga
    39961 aatgatcacc atgtcttaca atataagctg tagccgtttc ttcaacgata tcttttggat
    40021 taaaaatata accatcagat gctgaagaga gctccttact tgtcgttaaa gaagaaggat
    40081 tgcttgaaag actgcctaga ctagacacta cttcattagg ttttgcattt gtagaaactg
    40141 tagaaccagt tccactgata ggcaccattc tagcaatctt ttcttctaag gcagaaagct
    40201 tgctgtaagg aataaagtgg taatggtcgc catgcggaat cgcaactcca tttggtgtac
    40261 gactgataat cttagcaggg tcaaagacca ggccatctga ttcactgtaa cgttgggcgc
    40321 taggtgaatc atagagttcc ttcaaaagac tctggagatt ttcagattta tttgctggct
    40381 tgctagttga tccttttgct acagattgcg tgttattgtc actagctgtt gaagaatagc
    40441 ttaactgact cggttgcata ttttttccag ccagatgtgc tttagctgct gctaattcac
    40501 tagcagataa atcgcttttg ggaatgtagt gatagtgacc tccatgagga acgatataag
    40561 cattacccgt atcttcgata atatcagctg gattaaagac ataaccatca tttgtcgtat
    40621 atcgtccctg agaccttgct acagcaacat tagagttaac cttctcatta tctttgacat
    40681 gttcttgttt ttgacgattg atttcatctt tagttcgaac attatcagca tgagctgcat
    40741 ctttcaggta gacataatat tttccatcga ccttgatgat ataaccaccc ttgacttcat
    40801 tgacaatatc agcgtcttta agttgatagt ttggatcctt catcaagagt tcttcactaa
    40861 agagggcatc ataaggaact ttcccattat agtaatgata gtggtcaccg tgtgacgtta
    40921 catagccctg atctgtaatt ttgattacaa tttgctcggc ctgaattcct tctttctggc
    40981 taacctggtc tggtgtcaag ttttcacttt tctgacttga ctggctgcca tctacataag
    41041 agacacgatt attgtcctta ttttcctgcg aacgatgctg gtttagtgca taggcacata
    41101 gactcaagga tacgataaca gctgatccag ctgctatata ttttttacta aatttcataa
    41161 atccctcatt tcaataaatg atgaagtttt ttctcaactt cttttacttt attaaatagt
    41221 tttctaaacc ggttatttaa ccatttaatt aaccagtaaa tagtttacta tttaaaatta
    41281 cttttgtcaa gtttctgtta cgtttttcta aaaaagagaa gtaacacgaa aggttacttc
    41341 tccatagaat atgctccatt cattttacta ctgtatagga gccggttgac ttttttttaa
    41401 caaagccaag agactatcta cttctgctga aatagtgtta ttatctttcg ttccgagaag
    41461 aagactactt tttagaccag tcaatgtctc cacagcattt tgtctaatac tagaatctgt
    41521 tactttttct agcaaggcct ccgcctctgc tatcttagcg ttaataacag aatgctctac
    41581 ttgaggaatt tcagcctcat ctgtagtatc ttcagcttct tcctctgtat cttccgtatc
    41641 agtgcttggt ttataaagat tatctgctga aggatttaaa ccagcgtgat tctctttttc
    41701 atcagattca gggtgagttg gctcacttac ttcatcatgt tccttatctt cctcaggttt
    41761 ttctgtctga ggtttctcct cgtttggttt ttccgtttga ttggtatcag cttgaccatt
    41821 tttgtttctt tgaacatggt cgctagcgtt accaaaacca ttatctgaat gcggacgttc
    41881 gtttggatgt tcgacatagt acttgacagt cgccaaaaga tcctcaagag tatacccctt
    41941 aggtgcctca taaaggcctt cgtcaaacca ctcaaatttg atgttatggt aatgatcata
    42001 atgaggtatg attaaactac cgtttttgac ttctacagta tattgaagat tgtaaggcat
    42061 acgatcaagt ggcaccttct tagctgcttt cacgcggttg tagatagctt ctgctccttt
    42121 tgcctcagta tttcctgaat cctgatggt
//
LOCUS       DAVHSI010000018        33415 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.018, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000018 DAVHSI010000000
VERSION     DAVHSI010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.018"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            184..360
                     /locus_tag="VVR21_001079"
     CDS             184..360
                     /locus_tag="VVR21_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054977.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            762..2975
                     /locus_tag="VVR21_001080"
     CDS             762..2975
                     /locus_tag="VVR21_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU6054978.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFRKAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSDKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(3197..3673)
                     /locus_tag="VVR21_001081"
     CDS             complement(3197..3673)
                     /locus_tag="VVR21_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU6054979.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            3896..7099
                     /locus_tag="VVR21_001082"
     CDS             3896..7099
                     /locus_tag="VVR21_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU6054980.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQRWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKHGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            7478..7863
                     /gene="tnpA"
                     /locus_tag="VVR21_001083"
                     /pseudo
     CDS             7478..7863
                     /gene="tnpA"
                     /locus_tag="VVR21_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(8242..8871)
                     /locus_tag="VVR21_001084"
     CDS             complement(8242..8871)
                     /locus_tag="VVR21_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU6054981.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(8881..9882)
                     /locus_tag="VVR21_001085"
     CDS             complement(8881..9882)
                     /locus_tag="VVR21_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU6054982.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(9913..10554)
                     /locus_tag="VVR21_001086"
     CDS             complement(9913..10554)
                     /locus_tag="VVR21_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU6054983.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(10573..11388)
                     /locus_tag="VVR21_001087"
     CDS             complement(10573..11388)
                     /locus_tag="VVR21_001087"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU6054984.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            11659..12093
                     /locus_tag="VVR21_001088"
     CDS             11659..12093
                     /locus_tag="VVR21_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6054985.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            12105..13295
                     /locus_tag="VVR21_001089"
     CDS             12105..13295
                     /locus_tag="VVR21_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU6054986.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            13306..13797
                     /locus_tag="VVR21_001090"
     CDS             13306..13797
                     /locus_tag="VVR21_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU6054987.1"
                     /translation="MTMPNIMMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELNQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            13812..14591
                     /locus_tag="VVR21_001091"
     CDS             13812..14591
                     /locus_tag="VVR21_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU6054988.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            14578..15396
                     /locus_tag="VVR21_001092"
     CDS             14578..15396
                     /locus_tag="VVR21_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU6054989.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            15396..15689
                     /locus_tag="VVR21_001093"
     CDS             15396..15689
                     /locus_tag="VVR21_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6054990.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            15711..17612
                     /locus_tag="VVR21_001094"
     CDS             15711..17612
                     /locus_tag="VVR21_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU6054991.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            17672..18673
                     /locus_tag="VVR21_001095"
     CDS             17672..18673
                     /locus_tag="VVR21_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6054992.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(18783..19118)
                     /locus_tag="VVR21_001096"
     CDS             complement(18783..19118)
                     /locus_tag="VVR21_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054993.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(19129..19371)
                     /locus_tag="VVR21_001097"
     CDS             complement(19129..19371)
                     /locus_tag="VVR21_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6054994.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(19382..19924)
                     /locus_tag="VVR21_001098"
     CDS             complement(19382..19924)
                     /locus_tag="VVR21_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU6054995.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(19940..20134)
                     /locus_tag="VVR21_001099"
     CDS             complement(19940..20134)
                     /locus_tag="VVR21_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6054996.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            20300..21250
                     /gene="rsmH"
                     /locus_tag="VVR21_001100"
     CDS             20300..21250
                     /gene="rsmH"
                     /locus_tag="VVR21_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU6054997.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            21262..21579
                     /gene="ftsL"
                     /locus_tag="VVR21_001101"
     CDS             21262..21579
                     /gene="ftsL"
                     /locus_tag="VVR21_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU6054998.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            21583..23835
                     /gene="pbpX"
                     /locus_tag="VVR21_001102"
     CDS             21583..23835
                     /gene="pbpX"
                     /locus_tag="VVR21_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU6054999.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGVQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            23837..24817
                     /locus_tag="VVR21_001103"
     CDS             23837..24817
                     /locus_tag="VVR21_001103"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU6055000.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            25426..27531
                     /locus_tag="VVR21_001104"
     CDS             25426..27531
                     /locus_tag="VVR21_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU6055001.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEAF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGATGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            27983..28318
                     /locus_tag="VVR21_001105"
                     /pseudo
     CDS             27983..28318
                     /locus_tag="VVR21_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(28385..28867)
                     /locus_tag="VVR21_001106"
     CDS             complement(28385..28867)
                     /locus_tag="VVR21_001106"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU6055002.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(28962..30446)
                     /locus_tag="VVR21_001107"
     CDS             complement(28962..30446)
                     /locus_tag="VVR21_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU6055003.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            30599..32206
                     /locus_tag="VVR21_001108"
     CDS             30599..32206
                     /locus_tag="VVR21_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU6055004.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENKKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTDQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            32365..32538
                     /locus_tag="VVR21_001109"
     CDS             32365..32538
                     /locus_tag="VVR21_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU6055005.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACGQSGSDTKTYSSTFGGNPTTF
                     NYLLDYYADNTVN"
     gene            complement(32531..33381)
                     /locus_tag="VVR21_001110"
                     /pseudo
     CDS             complement(32531..33381)
                     /locus_tag="VVR21_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10253 a         5912 c         7430 g         9820 t
ORIGIN      
        1 aagtaaagta tgttatcgta gaatacgata caatagtaaa aaagcaaaaa gaatgcgttt
       61 tatatttggg tttgaggctt ataaaatagg ataagcgtgc tgaaaactta gatatgacaa
      121 acaaaataaa atttttaaaa gctacagaga aacatggtat aatgtatcta aaggaggtag
      181 catatgtcct tagatataga taaagaaaag atgacaatca tgggaatagc ttttgaaaac
      241 cgatccgttt ttaagagtgt ttggtatgct ttaagtacaa atatgattga aggatggcga
      301 cctacggtta gtgatgttga aaaattacga gatgaagctc ttgctctggg gatgacttaa
      361 tgaagcgcaa ctgttatgag tcttatgact atgttgatcc ggataattta tataccgatc
      421 cgggttcttc agttctaaga aataagcagg aaggaaaaaa gcacgcgagc ttgaatatcg
      481 tatgattgct agtaagagtt tgaaattatt tatcaatcct atcttagtta atagtttaaa
      541 agtagtttgt ttcacaactg cataagctta gaaaagttga aaagtgataa ctctttaata
      601 aactcttggt ttgttaaaag atattttgtc cactacattt ttttcaattg actattgttt
      661 gtcatagata taacagatag aacattgcat tcagaataat gaaaaacgca tcaaaaatgg
      721 tgcgttctgt ttttatgcta ccataaaagg aggaaaacaa attgaaaatt tttaagggag
      781 agttttatcg aatctctgta ttaacagaca agctagtaag gttagaatac tctcaaactg
      841 gaagttttga ggatagaacg acacaactta tctataatag agattttggc caaatttcgt
      901 tagattatat cgagacatca aacgtactag atattatgac ggactatttt catctgcact
      961 ttaataaagg agaatttaac gccgaaaatt tatttataga attaaaagga aattttgccg
     1021 tatatggtag tcgctggtat tttggtgaat ctattgaaac gttaaaagga acagctcgga
     1081 ctctggataa ggcagatgga gcaatctcgt tagaagatgg aattattagc cgaaatggta
     1141 tagccttatt ggatgattct caaggattta tttgggatga acaatctggt tatattgaga
     1201 gagaaaatca aattgacctg tatttctttg cctatgggca tgattataga ggagcaatca
     1261 gagattttta ccatttgact ggttcaacac ccttgttgcc aagatatgct ttaggcaatt
     1321 ggtggagtag atattggcct tatacgtcgg atgaatactt ggatttaata gacagatttg
     1381 aaacagagaa aattccatta tctatcggtg tgttagatat ggattggcat ataactgaca
     1441 ttccagctcg ctttggaagt ggctggacag gatatagttg gaatagaaac ttaataccaa
     1501 atccagaaca gttattgcaa caacttcatg atagaaagct aaaactctcc ttaaatgtcc
     1561 atcctgctga tgggatacgg gcttatgaag aagcttatcc tcaaatcgca aaacggttgg
     1621 ggttaaatgt agaactagaa gaacctgcta tttttgattt ttttaatccc tcttttagga
     1681 aagcctactt taaagatgtt cattatgaac tagaaaagca gggagtagat ttttggtgga
     1741 ttgactggca acaagggaca caaggtatgc tagatccact ttggctttta aaccattatc
     1801 actatcagga tagttgtaaa aatgcagaag gtggtttgat tttatcaaga tatgcaggtc
     1861 ctggtagtca ccgctaccct gttggttttt caggggatac tattattagt tggaattcct
     1921 taagatttca accctatttt acagcgacag catctaatat cggttatagt tggtggagtc
     1981 atgatatcgg tggacatatg ttgggggatt atgacgaaga gctacaaact agatggctac
     2041 agtttggtgt ttttagtccg attactcgat tacatagttc tagaagtcct tttaatagta
     2101 aagaaccttg gtttttttca gaaacaacat ctaagattat gaagaaatac cttcgtttga
     2161 gacatcagat gattccctat ctatatacca tgaatgtaaa gacacatgag gaaggtgccc
     2221 cattaatcag tccaatctat tatttctatc cagagaatga tgagagctat aatgttccaa
     2281 accaatactt ttttggaaca gaactgatgg tggctcccat tgtagaaaag atggatttga
     2341 cattccaatc tgcaaaagta gatgtatggt tccctgaagg tgaatggtat gacttttttt
     2401 cagataaaaa atacacaggt ggtgtgaagt taagtgttta tagggacatc tcgactacgc
     2461 ctgtgtttgc aaaaagtggt gcaatcattc ccttggttgg ttctgagata ggtatgggtg
     2521 ttgatttacc tgaggttgta gattggtatg tattcccagg gaaacaacat tcttttgaaa
     2581 tgcttgaaga tcaaaatggt caaagatata aaacaagatt atcaatcgat tgggaaatgg
     2641 gaatggtaga gttagcatta caaggagatt ctagtatcgt tccaagcaat agaaaacata
     2701 gaattcattt taaaggaacg aatgtgtcta taattgaatt gccaaataag aatgatacag
     2761 ctaaatttga atggaaagat aataaaagga catctttaaa tgacgaagtt tttagactac
     2821 taaagacagc ttctcttcca tatgaattaa aagatagatt gttaaatcaa ttcatcaatg
     2881 cgaaaaactc tcatgactta atgaatatct tgcatcatca ggataaggaa ttgagagggc
     2941 gtttgttgga aatgatattt actagccaaa actaattgat ataattagaa agtcatttgt
     3001 ttagtgtata tgaagattct gtatggtatt cgttatcact ggtcacattg aaaatgtgaa
     3061 ataagcacct acaacataga ctttacaaca cttcatgttt catatcatgg ggtgtttttc
     3121 tatttaagtc aaagccaatc aaaaactctc actattcatc aggttaaagg aaacctaatc
     3181 atagtgagat tgtgaattat agtagagttt gtatcgcctc ttcaatttgt tttgggtctg
     3241 tttttgaaga aaagcgttca aagacttgcc catctcgacc gatgagaaac ttagcgaaat
     3301 tccattcgat tcgttttcct agtgggccag atttctggtc ttgtaaccag acatagagag
     3361 ggtctgcttc cttaccgttg accttaatct tggcaaaacg tgggaaggtg gtttgaaaat
     3421 gtaggctaca gaaggcgttg atttcctctg cgctgccggg tgcttgtccc ataaactgat
     3481 tgcaagggaa atccaatatt tcgaagcctt gatcttgata gcgttcatag agttcttgaa
     3541 gtccctggta ctggggcgtt aaaccacatc cagtagcagt gttgacaatc aagagaactt
     3601 tgccacgata gctatccaag ggagttgctt ggttgttttg gttcaaaacg gaaaaatcat
     3661 aaagtgaagt catgagggcc tcttttcttt ttctacattg taacagtttt tacttttttc
     3721 gtcgagtcgg atggaagata ttgttgaaga ataagccttc aatatgatag aaaccgttta
     3781 caaataactt taaaaatggt atgatttaat taaaccggtt tacttagttg ctataaatct
     3841 ctaatttgag atttagttcc tattgatttt acaatatgtt tattggagtg tatacatgca
     3901 aacaaaaaca aagaagctca ttgtgagttt gtcttcactt gttttatcag gatttttatt
     3961 aaaccattat atgacagttg gagcggaaga aacgactacg aataccattc agcaaagcca
     4021 gaaggaagtt cagtatcagc aaagggatac aaaaaattta gttgaaaatg gtgattttgg
     4081 tcagacggag gacggaagca gtccgtggac aggaagcaaa gctcagaggt ggtcagcttg
     4141 ggtagaccag aagaatagtt ctgcagatgc ctcaactcga gtcattgagg ctaaggatgg
     4201 ggctatcact atctcaagcc ctgagaaatt aagggcagcg gttcaccgta tggttcctat
     4261 tgaagctaag aaaaagtata aactgcgttt caagattaaa acagatcata aagtcgggat
     4321 tgccaaagtt cgtatcattg aggaaagtgg taaggacaag cgattgtgga attctgcaac
     4381 gacgtcagga acaaaggact ggcagaccat tgaagcagac tatagcccga ctttagatgt
     4441 tgataaaatc aagctggagt tattctatga aacaggaact gggactgttt cctttaagga
     4501 tattgagctg gtagaggtag cagaccagct ttctgaggat tctcaaacag ataaacagct
     4561 tgaggaaaag attgatttac caattggaaa aaaacatgtt ttttctcttg cggactatac
     4621 ttataaggta gaaaatcctg acgttgcttc agtcaaaaat ggaattttag aacctcttaa
     4681 ggaagggaca accaatgtca ttgtcagtaa agatggcaag gaagtgaaaa agattccttt
     4741 gaagattcta gcctctgtta aggatgcata cacagaccgt ttggatgact ggaatggcat
     4801 cattgctggg aatcaatact atgattctaa aaatgaacag atggccaaat taaaccagga
     4861 attggaagga aaggtagctg atagcctatc tagtatttca agtcaggcgg accgcaccta
     4921 tttgtgggaa aaattttcaa attataaaat gtctgcaaat ctgactgcca cttatcggaa
     4981 attggaggag atggccaagc aagtgaccaa tccttcttct cgttattatc aagatgaaac
     5041 tgtcgttcga acagtcaggg attccatgga atggatgcat aaacatgtct acaatagtga
     5101 aaagagcatt gttgggaact ggtgggatta tgaaatcggt acacctcgtg ccatcaacaa
     5161 taccttgtct ctgatgaaag aatacttctc tgatgaggaa attaaaaaat atacagatgt
     5221 gattgaaaaa tttgtaccag atcccgaaca tttccgaaag acgactgata acccattcaa
     5281 ggctctaggt ggaaacttag ttgatatggg aagggtaaaa gtaatagctg gtttactgcg
     5341 taaggatgat caagaaattt cttctaccat tcgctcgatt gagcaagtgt tcaagttggt
     5401 agaccaaggt gaaggttttt atcaagatgg atcctatatc gaccatacca atgttgccta
     5461 tacgggtgct tatgggaatg ttttgattga tggcctgtct caactgttgc cagtcattca
     5521 aaagaccaag aatccaatcg ataaagataa aatgcaaacc atgtaccact ggattgataa
     5581 atcgtttgct cctttgctgg tgaatggaga gctgatggat atgagtcgtg gacgctcgat
     5641 cagtcgtgca aatagcgagg ggcacgtggc cgcagtagaa gtactaagag ggattcaccg
     5701 aatagcggat atgtctgaag gagaaaccaa acaacgtttg cagagtcttg tgaagaccat
     5761 tgttcaatcg gatagttatt atgatgtctt taagaatttg aagacttata aggatatcag
     5821 tttgatgcaa tccttgttaa gtgatgcagg agtcgcaagt gttccaagaa caagttacct
     5881 atctgccttt aacaagatgg ataaaacagc catgtacaat gcagagaaag ggtttggatt
     5941 tggcttgtca ctcttttcca gtcgtacctt gaattacgaa cacatgaaca aggaaaataa
     6001 acatggttgg tatacgagtg atgggatgtt ctatctttac aatggcgatt tgagtcacta
     6061 tagcgatggc tactggccaa cagttaatcc atataagatg cctggtacaa cagagacgga
     6121 tgctaagaga gcggatagcg atacaggtaa agttctaccg tctgctttcg ttggaacgag
     6181 caaactagat gatgccaatg cgacagcaac catggatttc accaactgga atcaaacatt
     6241 gactgctcat aagagctggt ttatgctgaa ggataagatc gcctttttag gaagcaatat
     6301 ccaaaacact tcaacagata ctgctgcaac tacaattgac cagagaaaac tggaatcaag
     6361 taatccatat aaagtctatg tcaatgataa agaagcctcc cttacagaac aagaaaagga
     6421 ttatcctgaa acccaaagtg tctttttaga atcgtccgat tcgaaaaaga atattggtta
     6481 ctttttcttt aagaagagtt caatcagtat gagtaaggct ttgcaaaagg gagcctggaa
     6541 ggatatcaat gaaggacagt cagacaagga agttgaaaat gaatttctta cgattagtca
     6601 ggctcataag caaaatggag attcttatgg ctatatgctc atccctaacg tgggtcgtgc
     6661 caccttcaat caaatgataa aagagttaga aagtagcctc atcgaaaata acgaaaccct
     6721 tcagtctgtt tatgatgcca aacaaggagt ttggggcatt gtgaaatatg atgattctgt
     6781 ctctactatt tccaaccaat tccaagtttt gaaacgtgga gtctatacca ttcgaaaaga
     6841 aggggatgaa tataagattg cctactataa tcctgaaacc caggaatcag ctccagatca
     6901 ggaagtcttt aaaaagctag agcaagcagc tcagccacaa gtacagaatt caaaagaaaa
     6961 ggaaaaatct gaagaggaaa agaaccattc ggatcaaaag aatctccctc agacaggaga
     7021 aggtcagtca atcttggcaa gtctagggtt cttgctactt ggggcgtttt atttattccg
     7081 tagaggaaag aacaactaat ttgttcatca tctagatgaa ttacatgaaa ctgtggaaaa
     7141 tagaaaaaat ccgaagaagg ccaaatatct tcggattttt cttttaaaaa agataagttg
     7201 atacttatct tttttacttc attatgtgac tatagcgttt tgaaactaga ataggacgtc
     7261 ataactgcta aaagatttct ataaattcat ttgattttcc taatcaattt gttcgtatcc
     7321 tatttcactc cactatatta gtccgtctcg ctccgtgagg tgcgagacaa aacaaccacc
     7381 cgctatgcgg gtgcgcgtcg aaggttatac caaaaaaact ccaaacgcga tacaataaag
     7441 gtgttcaatc cacttgtaaa gcgaaaggag aaaaaatatg gcacaaaagg ctcatagttt
     7501 atctcacaca aagtggaggt gttctatcac attgtgttca cccctaagta tagacgaaaa
     7561 gtcatctata atcaatatag aagtagttta ggcgaaatat ttcatcgctt gtgtagttat
     7621 aaaggtgttg aaatgatcga gggtcactta atgccagacc atgtacacat gttagtcagt
     7681 attccactaa ggctaagtgt ttcgagtttc atgggttatt taaaaggcaa aagtgcactc
     7741 atgatgtttg acaaacacgc caatctcaag tacaagtttg ggaatcggca tttctgggcg
     7801 gaaggttatt atgtaagtcc agtagggctt aatgaagcca caattaagaa atatagtcaa
     7861 gattaaagaa attatccagt ggatgatttc ttcacgagta tgaaaatttg agaactagta
     7921 aagtatgata tatagtaaaa tgaaataaga acaggacaaa atcgatcagg acagtcaaat
     7981 cgatttttaa caatgtttta gaagtagagg tgtactattc cagtttcaat ctactatagc
     8041 actagataaa ttgagtgtaa aagaatatga ggatcccttt agggatagtg gtaagtaata
     8101 ccaaagtctc ttaaagaggc aagtgacgag tcaagagcaa taaggcttga acaacgtgaa
     8161 agccagcgtc tttaggcgct ggctgatgat ttgggcttat agctctgaga taaaccaccc
     8221 gttagacggg tagttatgat tttatctgag tgtaacatac tgttgggcaa tctcgctgat
     8281 gcggtcaaag ttgccttggg aagcgagttt attgagttcg ccaccaattc caacggcatc
     8341 tgcaccagca gcgaaccatt gagggatgtt gtttaggccg actcctccgg ttaccattac
     8401 ggaaacttgt gggatcggtg ccttgactgc agagatatat gctggactga gagtactacc
     8461 tgggaagagt ttgatgattt cactaccggc ttcaagtgca gtcgtgatct ctgtgagggt
     8521 aatacagcct ggaatgtacg gtgtgctgta gagattgcac attttcgcag tttcagcatg
     8581 gaaagatgga gaaacaacgt aatttgctcc agctagaatg gcatctctag cagttacggc
     8641 atcaagcaca gtacctgcac cgatacaaac actctgatcg tcctgataca agtctacaag
     8701 ttccttgatg atttgtcctg catactgatt ggtataggcg atttcaatag ctttgatacc
     8761 gcccttgata caagcaatcg aggcttgtag tccttcttcc tttgtatttc ctcgaatgac
     8821 agcgacaatt ttctgttttt ttagttcaat aatcgtatct gatttggtca tgtaattctc
     8881 ctaacgaatg atatcttgtg catttgccag taaattttca atactagttg cggaagtgga
     8941 gagatggtct cctggaagag tgcatttgag agttgcgctc gcaactgcaa agtcaatggt
     9001 agtttttagg gaggaatgat ggagtagttg gtaaagggca ccagatataa aggcatcccc
     9061 gctaccaatt cgttgataga ctgcagtttt tagttggaca gactcttcaa atcgttcttc
     9121 cagagcatag gcttgataga catttttgtc ttgctcatca ctagatcgga gggtatggaa
     9181 aatagccttg aaaccatagg tttcttttaa aagtcgcatg cgattttcca cctcttctag
     9241 gctagcactg tctcttggaa acatctctag attttggtca tcaatcatga gaggatcaat
     9301 accgaagcaa tagtcagtaa aacgtgcaaa cttagaaaat tcatacttgg cttctagggc
     9361 tgaaatcatc tttgttctca gattgagatc cattgaaacg acaattcctc ggcgcttggc
     9421 ttcttccaag agtaggagaa ggatcgcacg gacctcttga ccgatagcta tggtgattcc
     9481 actaaaatga aaatggctaa tcccctgaaa gagagaatcc atatctagca tgtttggccg
     9541 aatctggctg atactcgtat gcttacgatc gtagaaaact tcactttgac gacaaccaaa
     9601 gccgttctcc aaatagtaga ggccgattcg atcgccaagc cgacagattg aactggtatc
     9661 gatttggtgc tgtttcaaga atgtgagaaa acgatctcca atctcgttgg cagggagtgc
     9721 ggtaaagact ttcgttgaga tacccagggc ttgcaaatta caagcgatgt taatttctga
     9781 tccgccaaaa taagtcgaac tggcaacatg atcgccgata ctggtggcat ctaatggtga
     9841 gattcgaatt aatggttcgc caaacagtaa tattttcgtc atccattagt tcctttctgg
     9901 tttagaatag ctttacttgg ctaatacttc tttcaaataa gcagcgactt catcatcttg
     9961 gcagttttca aagaagtatt cttggaagta tttgccagag atggtgtctt tgaggaagtc
    10021 ttggtcgatt gttttaagga tggtcatcaa atcattgtgg gtgatttgtt tcacctcgtt
    10081 taagatacga gcgttgcgtt gttcagggat tacacgttct cttgggtagc caccgcccat
    10141 ttcttcagca aataagcgtt caaacatcaa tttgagggtc agttctgccc cccagccaaa
    10201 tcctttggca taagggatag acaaggcgtt accaccattg atttgagaat aaaggtaagc
    10261 gtcagttggg tccactgcta gaccacagac aacaccaggg aagctgttta aagcaagcat
    10321 agcccctaca cccgtaccac agccggtaac aacaaagtca actgcctttg tatttaaaag
    10381 gatggcagcc attagtccgt tctgcacata agttaattga ctttctcctt cttctccacg
    10441 cataccatag ttaaataatt ggtagtcttt tttatctgtc gcttctttta gactatcgta
    10501 aataatgtga ttcttgctag cttgactatt ttcattgatt aatgcgattt tcataagatc
    10561 ttctttctat ttttactcag gttgttttcc gatgtaggct aagataccgc catctacata
    10621 taggatgtgg ccattgacaa aattgctggc atcactagcg agaaagacag cagggcccat
    10681 caaatcttca ggatttcccc aacgtgcagc aggtgttttt gcaatgatga actggtcaaa
    10741 tgggtggcga gaaccatctt cttgcaactc acgaagaggt gctgtttgag gagtggcaat
    10801 ataacctggt ccaattccgt tacattggat attggctcca ccgtattcag acgcaatgtt
    10861 gcgggtcaac attttcaagc cccctttagc agcagcataa gcgctaactg tttcacgtcc
    10921 cagttcgctc atcatcgaac aaatattgat aatctttcca tgccctttct ttatcataga
    10981 aggaataact gcctttgaaa cgataaatgg tgcgtttaag tcaatatcga tgaccttacg
    11041 gaaatcagcg gcgctcattt cgcacattgg aactcggcgg ataataccag cgttattaac
    11101 gaggatgtca atgacaccaa cctcttgttc gatttgcttg accatggctt ggataccgtc
    11161 ctcgtctgtc acgtcacaga catatccatg ggcttcgatg ccaacttcac gataagcttc
    11221 aatcccttta ttgaccagat cttgattgat atcgttaaag acaatagtag cgccggcttc
    11281 agcgtaggat ttggcaatag caaatccaat tccataagaa gcgccggtga tgagagcaat
    11341 ttttcctttt aaagaaaact gctcaattga gaatgatgta tttgtcattt gatacttcct
    11401 ttcaaatttg ttaagacttc tctataatca aattatattc tagtaaaccg gttttgtcaa
    11461 taaataaata tttttattta taaaaagatt tattttcctt aaaaatggaa tattttgaaa
    11521 tttctgtcta ttaaaatgat taaaaagata atgaaagcgc taatattttt taaaaaaaac
    11581 tattgacaag ataaaaataa aggattacaa tggggaatat aaagtaaacc ggtaaaccta
    11641 aacaagaaag gagaaaagat gaaaattgta cttgtagggc atggacattt tgctacaggg
    11701 atttatagtt ctttacaatt gattgcaggc aatcaagaaa atgtggaggc gattgacttt
    11761 gtggaaggaa tgtcagcaga tgaactcaag caaaaaatct tacttgcaat ttcaaatgaa
    11821 gaagaagttt taatcctaag tgatctcttg ggaggatcgc cattcaaggt ttcttctacc
    11881 ataatgggag aaaatccagc caaaacaatg aatgttctct cgggtttgaa cttagccatg
    11941 ttaatggaag cagtctttgc tagaatggct catagctttg atgaggttgt taataaatca
    12001 gtagtggcgg cccagggcgg agtcgtaaat ggtaaagaat tgttttcaac ggatgcagag
    12061 gaagaggaag aagatttcga atcgggtatt taaagggtaa aagaatgata aaaaaggtta
    12121 cgattgaaaa aataaaatcg cctgagcgct tcttagaagt accacttctg acgaaagaag
    12181 aagtcggcca ggcaatcgat aaggttattc ggcagttaga actcaacctt gactatttca
    12241 aggaagattt cccgacgcca gctacctttg ataatgtcta tccaatcatg gataacacgg
    12301 aatggaccaa tggtttctgg acaggagaac tgtggttggc ttatgaatac agtcaacagg
    12361 atgcatttaa aaacatcgct cataaaaatg ttctttcttt cctggatcgt gtcaataaga
    12421 gagtagaatt ggctcaccat gatctcggct tcttgtacac accgtcttgt atggctgaat
    12481 ataagataaa tggagatgga gaggctagag aagcagcctt gaaagctgca gataagttga
    12541 ttgaacgcta tcaagaaaaa ggtggtttta ttcaagcttg gggagacttg ggcaagaaag
    12601 agcattaccg tttgattatc gattgcttgc tcaatatcca actcttattc tttgcttatc
    12661 aagaaacagg cgatcaaaaa tactacgata ttgcagaaag ccatttctat gcttcagcta
    12721 ataatgtaat ccgtgatgac gcttcgtcct tccacacctt ctattttgat cctgagacag
    12781 gtcaaccctt taaaggtgta acgagacaag ggtatagtga tgattcatgc tgggcacgtg
    12841 gtcagtcatg gggagtttat ggtattcctt tgacttatcg tcacttaaaa gacgagtcct
    12901 gctttgactt gtttaagggt gtgaccaatt atttcttgaa tcgtctacca aaagatcatg
    12961 tgtcctattg ggatttgatt tttaatgatg gtagtgatca atcacgagat tcttcagcaa
    13021 cagctatcgc cgtctgtggg attcatgaaa tgctaaaaca tctcccagag gtggatgctg
    13081 acaaagatat ttataaacat gctatgcatg ccatgcttcg ttccttgatc gaacattatg
    13141 caaatgatca atttacccct ggtgggacaa gtctcctcca cggtgtgtac tcatggcatt
    13201 caggtaaagg agtggatgaa ggcaatatct ggggtgacta ctattaccta gaagccctta
    13261 tccgtttcta caaagactgg aacctatatt ggtaggagga gaaatatgac aatgccaaat
    13321 attatgatga cccgtatcga tgaacggttg attcatggac aaggacaact ttgggtaaaa
    13381 tacctaggtt gtaatacggt cattgttgcc aatgacgaag taagcacgga caagatgcaa
    13441 caaactctga tgaaaacagt tgtgccagac tcagttgcca tgcgtttctt ccctttgcaa
    13501 aaggtgattg atatcattca caaggctaat cctgctcaaa cgatctttat cgttgtaaag
    13561 gatgtgaagg acgctttaac cttggtagaa ggtggtgtcc ctatcaaaga aatcaatatt
    13621 gggaacattc acaatgctac tggtaaagag caagtgacac gctccatctt cctgggtgaa
    13681 gaggacaagg cggccctcaa ggaattgaac caaactcatc aagtaacatt taatacgaaa
    13741 acaactccaa caggaaatga tggagctgtt caagtcaaca ttatggacta tatttaaaag
    13801 aggagatcgt tatgtcgatt aatgtatttc aagcgatttt aattggatta tggacagctt
    13861 tctgttttag tggaatgctg ttaggaattt acaccaatag atgtattgtt ctgtcatttg
    13921 gtgtcggaat tattctaggt gatctgccta ctgctcttgc aatgggagct attggtgaat
    13981 tggcttatat gggattcggt gttggtgctg gaggtactgt tccaccaaac ccaatcggac
    14041 ctggtatctt tggtaccttg atggctatca ctagtgctgg taaagtcagt ccagaagcgg
    14101 ctcttgccct ctctactccg attgctgtgg cgattcaatt cttacaaact ttcgcctaca
    14161 ctgtacgtgc tggtgcgcct gaaacggcga tgaagcactt gaaaaaccat aatttgaaga
    14221 aattcaagtt cactctaaat gcaacaattt ggttgtttgc ctttattgga tttaccttgg
    14281 gttgcttggg tgccctttca atggatacct tgttgaaact cgtagactac attccaccgg
    14341 tattgcttac aggtttgaca gttgctggta aaatgctccc agctatcggt tttgcgatga
    14401 tcttgtcagt gatggctaag aaagagttga ttccctttgt cttgttggga tatgtttgtg
    14461 cagcttatct aaacatccca acaattggta ttgcaattgt aggtactatc tttgctttga
    14521 ttgaatttta taacaagcca aaaacagcgg atcatgtggt agaggaggaa gcacacgatg
    14581 actggatcta acaaattaac aaaacgtgat tatcttaaaa cgtctttgcg ggcattcttt
    14641 tgtcaaaatg gatttaacta tagtaactat caagggttgg gatatgccaa tgtgatgtat
    14701 cctgctttga aaaaacacta tggagaggat caggaaggtt tctaccaagc cttggaagaa
    14761 aactgtgaat tctataatac caacccacac ttcctgcctt ttattaccag cttgcatctt
    14821 gtaatgttgg aaaatggccg tccggcaaaa gaaacacgta gtatcaagat ggccttgatg
    14881 ggaccattgg caggtattgg ggattctctt tctcaattct gtttagctcc attgttctca
    14941 accatcgcag cttcgtttgc tcaagaaggc ttggttgtcg gtccaatctt gttcttcctt
    15001 gcgatgaata cgattttaac agcgattaaa ttgtcaactg gtctgtatgg atacaaacta
    15061 ggaacaactg tgattgataa actaagcgaa cagatggcaa cgatttctcg tattgccaat
    15121 attatcggtg taaccgtaat tgctggtttg gcagcgacat ctgttaagat tatggtgccg
    15181 attacctttg ctgcagggga agttaaagca gacgctaaac aaagtatcgt aagtattcag
    15241 ggaatgcttg ataaggttgc tccagctctt ctaccagccc tatttacact tttagtttac
    15301 tacttgatca aagaaaagaa atggacaaca tataaactcg ttattttaac agttatcatc
    15361 ggaattatcg gaagctggct taagattata gcttaatgga tacaacattg ttttatggaa
    15421 tagtgattgt cttggcagtg agtccccttt tactgtcaag ctttcattct attcgtcagc
    15481 aaaagttgct tcgcaaacag atggagcaac gacaagagta tttagcttct ttaacatctg
    15541 gtgatgaagt gttgttattg tctggaattc atggaaaaat catttctatc caagatgact
    15601 tggtctcctt gcagattgca aaaggtgtgg tcatctatgt agaaaaggaa agtgtaatgg
    15661 gaaagacaaa agaactgctt tttaagtagt tctttttctg gtaatagata atgaaagaag
    15721 aaagaagaca attttttgaa agaatcgatg gaaaccaatg tcgtgattat atcttgtcgc
    15781 actgttcaaa agactatgag aaagtcaaga gttcccttga acgcttgatg gacaatcgtt
    15841 ttatgtttga tagtccttgg gatatggagc cttgttcaaa aatccatcaa atccagccga
    15901 tggtatggga tcaagtattt gaagatgatc cagaatgggc ttatatgctc aatcgacaag
    15961 aatatctctt gcagtttatg atagggtatg tggtagaagg agataaggac tatattcaaa
    16021 agtgcaagtt ctttctattt gattggattg agcaggtgag agaattttct cctcaatcct
    16081 tgatgactag aaccttggat acgggtattc gttcctttac ttggttgaaa ctactcttgc
    16141 ttctcttgaa atttgacttg ctagaggaga aagaactaga gaaaattttg gtcagtctag
    16201 aaaagcagat tgactttatg aaaagctact atcgcgccaa gtacaccctt agtaactggg
    16261 ggattttaca aacaattccg atgcttgcta tctatcattt cttttcagat aagatggacc
    16321 tagaagaagc ttaccatttt gcttcagagg agttgaaaca gcaaattgag acacagattt
    16381 taggagatgg aagccagttt gaacagtcga ttctctatca tgtagaggtt tataaagcct
    16441 tgctggattt gtgtctcttg cttccagact tgcaagatag ttaccaagag ttgctggaaa
    16501 agatggcgac ctatattcaa atgatgacag gcttagatgg acggactttg gcttttggtg
    16561 atagcgattc tacagaaacg acagaaatgt tgagcctgtc tgctgtggtt ttgaacaagg
    16621 aagaccttct taacggtctg gatgttaaag ttgatttgct tagcctcttg ttcctggggc
    16681 gagaaaaggt caagcgactg caggaatttg aaaggagagc ttggcagcct aagtccatga
    16741 tctttgaaga ctctggacat gtctgcatta aggatgaaca tcgttatcta tttttcaaaa
    16801 atggtccgct aggaagtgcc catagccata gtgacgagaa tagtttttgc ttacagtatc
    16861 aaggccaacc tattttcata gatgctgggc gttattctta tcgggagata tatgaacgtt
    16921 atctcttaaa gagtgcttgg agtcattcga cctgcattgt agatgggaaa gctccggaaa
    16981 gaatcacggg atcctgggaa tatgaatact atcctcactc cctgttttgt caccataaag
    17041 aaagggaggg agtgcattat attgaggggg cttattggtc agcagaacct gatttgcctt
    17101 atcttcacaa gagaaaaatc ctcatgttgg tagaggatgt ctggctcttg gtagatgaca
    17161 tcaggtgtca aggtcagcat gaggcgttga ttcagtttat ccttgacaag gatgtgacct
    17221 atcaagatgg gaaaatcaat cagttgagac tatggagtga agttgatttt gatttggaag
    17281 ataccatcat ttctcctaaa tacaatgagc ttgaaagaag tagcaaactc accaagcgcc
    17341 aattctttga gaatcagatg ctggattata ccatcattgc gcatgagagt tttgaaatca
    17401 tccgtcattc tgtctaccag acagatgatc gtgaagtgga aaatgctctg gcttttgaag
    17461 tgaaaaatga cgaaacagac aagctgattc tgttattaag cgaggatatt ggtgtaggtg
    17521 aaaaattgtg cctcgttgac ggaacaaaaa tgcgtggaaa atgtctagta tatgataaaa
    17581 taaatgagag aatgattcgc ttgcagtgct agaaataggc attttgaata gtgaacatgt
    17641 tataataagt attagtagga ggtgttttag attggagaag aaactgacca taaaagacat
    17701 tgcggaaatg gctcagacct cgaaaacaac cgtgtcattt tacctaaacg ggaaatatga
    17761 aaaaatgtcc caagagacac gtgaaaagat tgaaaaagtt attcatgaaa caaattacaa
    17821 accgagcatt gttgcgcgta gcttaaactc caaacgaaca aaattaatcg gtgttttgat
    17881 cggtgatatt accaacagtt tctcaaacca aattgttaag ggaattgagg atatcgccag
    17941 ccagaatggc taccaggtaa tgataggaaa tagtaattac agccaagaga gtgaggaccg
    18001 gtatattgaa agcatgcttc tcttgggagt agacggcttt attattcagc cgacctctaa
    18061 tttccgaaaa tattctcgta tcatcgatga gaaaaagaag aaaatggtct tttttgatag
    18121 tcagctctat gaacaccgga ctagctgggt taaaaccaat aactatgatg ccgtttatga
    18181 catgacccag tcctgtatcg aaaaaggtta tgagcatttt ctcttgatta cagcggatac
    18241 gagtcgtttg agtactcgga ttgagcgggc aagtggtttt gtggatgctt taacagatgc
    18301 taatatgcgt cacgccagtc taaccattga agataagcat acgaatttgg aacaaattaa
    18361 agaattttta caaaaagaaa tcgatcccga tgaaaaaact ctggtattta tccctaactg
    18421 ttgggcccta cctctagtct ttaccgttat caaagagttg aattataact tgccgcaagt
    18481 tgggttgatt ggttttgaca atacggagtg gacttgcttt tcttctccaa gtgtttcgac
    18541 gctggttcag ccctcctttg aggaaggaca acaggctaca aagattttga ttgaccagat
    18601 tgaaggccgc aatcaagaag aaaggcaaca agtcttggat tgtagtgtga attggaaaga
    18661 gtcgactttc taaaatgaag gaaaatgact tgcaatctct gttaagaaat aaaataatcc
    18721 cacctagaac aagctaggtg ggattatttg cctatgaaat gagaaattat gggagcaagc
    18781 tcctaaatca actgtttttg atctacttct ttaactactt gataaaagtt atagaagtag
    18841 gccaaacttg aaatgatggt tacgactagg aatattgaaa atttccattg gacagggttg
    18901 gttaaaagtt gtggaaagga tatgaggaga aagaagaggg ctgcgttgag gacaggtatc
    18961 cgttttgatt gtattttctc aagtccttta ttgagcgcag gaagaaagag gagtaggagt
    19021 agtaaaactg tatgagaaac agctcctgaa ataagggcaa agaaaaggaa aatactgata
    19081 aaaacatgaa tgatcagtag tctagctagt gatttcataa ggtacctcct aatcctggtc
    19141 ttttttagct cttgcaatac gaagtgagtc gacaatatgt atcatcactc cgaaaaagaa
    19201 agctcccagt atagttttaa aaatatgttt tgtatttaga agagaactga taaaatttgg
    19261 attttcactt gttagggtat caatgagtgg aattataaaa aatatcactg ttccataaat
    19321 cgaacctgct ttcagaccag gataacgtaa ctgtctcttt tcttttttca tgagtttcct
    19381 cctaatcctc atcttgattt ttcttagttt ttgcaatgcg acgggagatg aggaactgta
    19441 tgctcgctcc gaagaaaata gaaccgagaa tgcttgatac accatttctt atagtgagaa
    19501 gagaatgaaa atagtcctga ccttcatcta tgagtatact gagaagagga gttataaaaa
    19561 acatccatag accaaagaac aaacctgctt tcagacctgg gtagtgtagt tgcttgcttt
    19621 ctttctcatt cagcatatct ggttcaatga ctgtgatgcc tgtttttttc atttggtagg
    19681 tgacatagcc agaagcgatg agggcaatca ctaaaatcag agggggatag attagagcca
    19741 cttcttgagg gtatttatag gctagaagga gtggaataat atttccgaaa atcatcagat
    19801 aaaagaggac gataaagact tggttcccaa tactatcggc ctcacgccgt ttgtattcgt
    19861 caaggggacc agaaataccg tatgtgcgtt tgatcagttt ttcagtgaag gtttcttttt
    19921 tcatgagttt gctccttttt taaaaatctt cctcccaaaa gagactgttg aggtcagttt
    19981 ggaggctgcg ggcgagattg agacagagtt ccaaggttgg attgtacttg tcgttttcaa
    20041 tcatattgat agtctgtctc gagacaccga tatccttggc gagttcgagc tgggaaatac
    20101 ccaattcctt gcgaaattct ttcacacgat tcatctggtc tcctttctga tttatgtcgt
    20161 atatatttga ctatattata gtcttttaaa cataaagtgt caagtatttt tgacatattt
    20221 tttgaagaaa tagtagtctc cttgtcctat ttgtctgaca agtgcaagct ggtcggattt
    20281 gtggtaaaat agataagata tgacaaaaga atttcatcat gtaacggtct tactccacga
    20341 aacgattgat atgcttgacg taaaacctga cggtatctac gttgatgcga ctttgggtgg
    20401 agcaggccat agcgagtatt tattaagtaa attaagtgaa aaaggccatc tctatgcctt
    20461 tgaccaggat cagaatgcca ttgacaatgc gcaaaaacgc ttggcacctt acattgagaa
    20521 gggaatggtg acctttatca aggacaactt ccgtcattta caggcacgtt tgcgcgaagc
    20581 tggtgttcag gaaattgatg gaatttgtta tgacttggga gtgtctagtc ctcaattgga
    20641 ccagcgtgag cgtggttttt cttataaaaa ggatgcgcca ctggacatgc ggatgaatca
    20701 ggatgctagt ctgacagcct atgaagtggt gaacaattat gactatcatg acttggttcg
    20761 tattttcttc aagtatggag aggataaatt ctctaaacag attgcgcgta agattgagca
    20821 agcgcgtgaa gtgaagccga ttgagacaac gactgagtta gcagagatta tcaagttggt
    20881 caaacctgcc aaggaactca agaagaaggg tcatcctgct aagcagattt tccaggctat
    20941 tcgaattgaa gtcaatgatg aactgggggc ggcagatgag tccatccagc aggctatgga
    21001 tatgttggct ctggatggta gaatttcagt gattaccttt cattccttag aagaccgctt
    21061 gaccaagcaa ttgttcaagg aagcttcaac agttgaagtt ccaaaaggct tgcctttcat
    21121 cccagatgat ctcaagccca agatggaatt ggtgtcccgt aagccaatct tgccaagtgc
    21181 ggaagagtta gaagccaata accgctcgca ctcagccaag ttgcgcgtgg ccagaaaaat
    21241 tcacaagtaa gagggaaaaa gatggcagaa aaaatggaaa aaacaggtca aatactacag
    21301 atgcaactta aacggttttc gcgtgtggaa aaagcttttt acttttccat tgctgtaacc
    21361 actcttattg tagccattag tattattttt atgcagacca agctcttgca agtgcagaat
    21421 gatttgacaa aaatcaatgc gcagatagag gaaaagaaaa ccgaattgga cgatgccaag
    21481 caagaggtca atgaactatt acgtgcagaa cgtttgaaag aaattgccaa ttcacacgat
    21541 ttgcaattaa acaatgaaaa tattagaata gcggagtaag atatgaagtg gacaaaaaga
    21601 gtaatccgtt atgcgaccaa aaatcggaaa tcgccggctg aaaacagacg cagagttgga
    21661 aaaagtctga gtttattatc tgtctttgtt tttgccattt ttttagtcaa ttttgcggtc
    21721 attattggga caggcactcg ctttggaacg gatttagcga aggaagctaa gaaggttcat
    21781 caaactaccc gtacagttcc tgccaaacgt gggactattt atgaccgaaa tggagtcccg
    21841 attgctgagg atgcaacctc ctataatgtc tatgcggtca ttgatgagaa ctataagtca
    21901 gcaacgggta agattcttta cgtagaaaaa acacaattta acaaggttgc agaggtcttt
    21961 cataagtatc tggacatgga agaatcctat gtaagagagc aactctcgca acctaatctc
    22021 aagcaagttt cctttggagc aaagggaaat gggattacct atgccaatat gatgtctatc
    22081 aaaaaagaat tggaagctgc agaggtcaag gggattgatt ttacaaccag tcccaatcgt
    22141 agttacccaa acggacaatt tgcttctagt tttatcggcc tagctcagct ccatgaaaat
    22201 gaagatggaa gcaagagctt gctgggaacc tctggaatgg agagttcctt gaacagtatt
    22261 cttgcaggga cagacggcat tattacctat gaaaaggatc gtctgggtaa tattgtaccc
    22321 ggaacagaac aagtttccca acgaacgatg gacggtaagg atgtttatac aaccatttcc
    22381 agccccctcc agtcctttat ggaaacccag atggatgctt ttcaagagaa ggtaaaagga
    22441 aagtacatga cagcgacttt ggtcagtgct aaaacagggg aaattctggc aacaacgcaa
    22501 cggccgacct ttgatgcaga tacaaaagaa ggcattacag aggactttgt ttggcgtgat
    22561 atcctttacc aaagtaacta tgagccaggt tccactatga aagtgatgat gttggctgct
    22621 gctattgata ataatacctt tccaggagga gaagtcttta atagtagtga gttaaaaatt
    22681 gcagatgcca cgattcgaga ttgggacgtt aatgaaggat tgactggtgg cagaatgatg
    22741 actttttctc aaggttttgc acactcaagt aacgttggga tgaccctcct tgagcaaaag
    22801 atgggagatg ctacctggct tgattatctt aatcgtttta aatttggagt tccgacccgt
    22861 ttcggtttga cggatgagta tgctggtcag cttcctgcgg ataatattgt caacattgcg
    22921 caaagctcat ttggacaagg gatttcagtg acccagacgc aaatgattcg tgcctttaca
    22981 gctattgcta atgacggtgt catgctggag cctaaattta ttagtgccat ttatgatcca
    23041 aatgatcaaa ctgctcggaa atctcaaaaa gaaattgtgg gaaatcctgt ttctaaagat
    23101 gcagctagtc taactcggac taacatggtt ttggtaggga cggatccggt ttatggaacc
    23161 atgtataacc acagcacagg caagccaact gtaactgttc ctgggcaaaa tgtagccctc
    23221 aagtctggta cggctcagat tgctgacgag aaaaatggtg gttatctagt cgggttaacc
    23281 gactatattt tctcggctgt atcgatgagt ccggctgaaa atcctgattt tatcttgtat
    23341 gtgacggtcc aacaacctga acattattca ggtgttcagt tgggagaatt tgccaatcct
    23401 atcttggagc gggcttcagc tatgaaagac tctctcaatc ttcaaacaac agctaaggct
    23461 ttggagcaag taagtcaaca aagtccttat cctatgccca gtgtcaagga tatttcacct
    23521 ggtgatttag cagaagaatt gcgtcgcaat cttgtacaac ccatcgttgt gggaacagga
    23581 acgaagatta aaaacagttc tgctgaagaa gggaagaatc ttgccccgaa tcagcaagtc
    23641 ctcatcttat ctgataaagc agaggaggtt ccagatatgt atggttggac aaaggagact
    23701 gctgagaccc ttgctaagtg gctcaatata gaacttgaat ttcaaggctc gggctctact
    23761 gtgcagaagc aagatgttcg tgctaacaca gctatcaagg acattaaaaa aattacatta
    23821 actttaggag actaatatgt ttatttccat cagtgctgga attgtgacat ttttactaac
    23881 tttagtagga attccggcct ttatccaatt ttatagaaag gcgcaaatta caggccagca
    23941 gatgcatgag gatgtcaaac agcatcaggc aaaagctggg actcctacaa tgggaggttt
    24001 ggttttcttg attacttctg ttttggttgc tttctttttc gccctattta gtagccaatt
    24061 cagcaataat atgggaatga ttttgttcat cttggtcttg tatggcttgg tcggattttt
    24121 agatgacttt ctcaaggtct ttcgtaaaat caatgagggg cttaatccta agcaaaaatt
    24181 agctcttcag cttctaggtg gagttatctt ctatcttttc tatgagcgcg gtggcgatat
    24241 gctttctgtc tttggttatc aagtgcatct agggattttc tatattgtct tcgctctttt
    24301 ctggctagtc ggtttttcaa acgcagtaaa cttgacagac ggtgttgacg gtttagctag
    24361 tatttccgtt gtgattagtt tgtctgccta tggagttatt gcctatgtgc aaggtcagat
    24421 ggatattctt ctagtgattc ttgccatgat tggtggtttg ctcagttttt tcatctttaa
    24481 ccataagcct gctaaggtct ttatgggtga tgtgggaagt ttggccctag gtgggatgct
    24541 ggcagctatc tctatggctc tccaccaaga atggactctc ttgattatcg gaattgtata
    24601 tgtttttgaa acaacttctg ttatgatgca agtcagttat ttcaaactga caggtggtaa
    24661 acgtattttc cgtatgacgc ctgtacatca ccattttgag cttgggggat tgtctggtaa
    24721 aggaaatcct tggagcgagt ggaaggttga cttcttcttt tggggagttg ggcttctagc
    24781 aagtctcctg acccttgcaa ttttgtattt gatgtaagaa tggcaccctg atgtttcagg
    24841 gtgtttttgt gtttaaatac acaatgaaaa tcaaagaaca aactagaaag ctaactttag
    24901 gctgctcaaa atatagtaga ttgaaactag aatagtacac ctctacttct aaaacatttt
    24961 tagaaatcga tttgactgtc ctgattgatt tgtcctgttc ttatttcatt ttattataca
    25021 gttttgagat ggttgataga actgacgaag tcagctcaaa acacggtttt gaggttgtag
    25081 ataaggagaa gctgatgtag tttgaagagg ttttcgaaga gtgtaaaaaa atattggtca
    25141 gttaaagtca aaacccttga ccttttctga ccaatgtagt atattatgaa cgtaaggtaa
    25201 atgaaagcct tactagaaca cttatttaaa gtaaaataga aagaggtggg tctatgtttc
    25261 atctagaaat cttcagaagt aaagatagtc tactcctgct tgaaaaagaa aaaccagaaa
    25321 tagtacgtag ggtagcgatc tagctagtct aaatttttta aaacaatggt caaagatagt
    25381 caatatcagt aatcataact aagtaaacaa aaagaggtaa agaatatgaa taacaacttt
    25441 aataatttta ataacatgga tgatttattt aaccaattga tgggtggtat gcgaggatac
    25501 agttctgaaa atcgccgtta cttaattaat ggacgcgaag tcacacctga ggcatttgct
    25561 cactatcgtg cgactggtca attaccagga aatgcagaaa ctgatgtgca aatgccccaa
    25621 caggcatcag gtatgaaaca agacggtgtc cttgcaaaac taggtcgaaa cttaacagca
    25681 gaagcgcgtg agggcaagtt ggatcctgtt atcggacgaa acaaggaaat tcaagaaaca
    25741 tctgaaatcc tctcacgccg caccaagaac aatcctgttt tggtcggaga tgcaggtgtt
    25801 ggtaagacag cagttgtcga aggtctagcg caagccattg tgaacggaga tgttcctgct
    25861 gctatcaaga acaaggaaat tatttctatt gatatctcag gtcttgaggc tggtactcaa
    25921 taccgtggta gctttgaaga aaatgtccaa aacttagtca atgaagtgaa agaagcaggg
    25981 aatattatcc tcttctttga tgaaattcac caaattcttg gtgctggtag cactggtgga
    26041 gacagtggtt ctaaaggact tgcggatatt ctcaagccag ctctctctcg tggagaattg
    26101 acagtgattg gggcaacaac tcaagacgaa taccgtaaca ccatcttgaa gaatgctgct
    26161 cttgctcgtc gtttcaacga agtgaaggtc aatgctcctt cagcagagaa tacttttaaa
    26221 attcttcaag gcattcgtga cctctatcaa caacaccaca atgtcatctt gccagacgaa
    26281 gtcttgaaag cagcggtgga ttattctgtt caatacattc ctcaacgtag cttgccagat
    26341 aaggctattg accttgtcga tgtaacggct gctcacttgg cggctcaaca tccagtaaca
    26401 gatgtgcatg ctgttgaacg agaaatcgaa acggaaaaag acaagcaaga aaaagcagtt
    26461 gaagcagaag attttgaagc agctctaaac tataaaacac gcattgcaga attggaaagg
    26521 aaaatcgaaa accacacaga agatatgaaa gtgactgcaa gtgtcaatga tgtggctgaa
    26581 tctgtggaac gaatgacagg tatcccagta tcgcaaatgg gagcttcaga tatcgaacgt
    26641 ttgaaagata tggctcatcg cttgcaagac aaggtgattg gtcaagataa ggccgtagaa
    26701 gttgtagctc gtgctatccg tcgtaaccgt gctggttttg atgaaggaaa tcgcccaata
    26761 ggcagcttcc tctttgtagg ggctactggg gttggtaaga cggagcttgc taagcaattg
    26821 gcactcgata tgtttggaac ccaggatgcg attatccgtt tggatatgtc tgaatacagt
    26881 gaccgcacag ctgtttctaa gctaattggt acaacagcag gctatgtggg ttatgatgac
    26941 aatagcaata ccttaacaga acgtgttcgt cgcaatccat actctatcat tctcttggat
    27001 gaaattgaaa aggctgatcc tcaagttatt acccttctcc tccaagttct agatgatggt
    27061 cgtttgacag atggtcaagg aaatacagta aacttcaaga acactgtcat tattgcgacc
    27121 tcaaatgctg gatttggcta tgaagccaac ttgacagaag atgcggataa accagaattg
    27181 atggaccgtt tgaaaccctt cttccgtcca gaattcctca accgctttaa tgcagtcatc
    27241 gagttctcgc acttgactaa ggaagacctt tctaagattg tagatttgat gttggctgaa
    27301 gttaaccaaa ccttggctaa gaaagacatt gacttggtag ttagtcaagc ggctaaagat
    27361 tatatcacag aagaaggtta cgacgaagtc atgggggttc gtcctctccg tcgcgtggtt
    27421 gaacaagaaa ttcgtgataa ggtgacagac ttccacttag atcatttaga tgctaaacat
    27481 ctggaagcag atatggaaga tggcgttttg gttattcgtg agaaagccta agatagaatt
    27541 ttgaggataa aaaagaagga gccagctgaa aaaaactggt tccttttgag gtacgacggg
    27601 catgtcgtac agtgggttga aactagaata gtacacatct acttctaaaa tattgttaga
    27661 aatcgatttg actgtcctga ttgatttgtc ctgttcttat ttcattttac tatatatctg
    27721 aggtgtaagt cctcggtggg tacctgctac cggtgctccc aatagtgatt cccaagcctg
    27781 actatcgtga ggtagcggat taaaacggtc tggggataga ccgttttaag tctgacgctg
    27841 gaaataagaa tcgtcagagg aagggatagc gaaatcgtgg ctctacgaat aggaacgtga
    27901 taataaggcg tatatagcgg ataaggggcc tcaaactcta aagttcaaaa aggtagtcgt
    27961 agcctatatg tgtaaatcac gagagcaact gaatttgtct gttcgaggat ggataaacta
    28021 tttctcattg ggaaatatga aaagtatagt cactagcata gatgagcgct tgcatactcg
    28081 cctacgagtg attatctgga agcaatggaa gaaaaaatcg agacgattat ggggattgct
    28141 taagttaggg gttcctaaat ggatagcaga taaggtatct ggctggggcg accattatca
    28201 attagtagct cagaagtcgg tacttaaacg tgctatatca aaaccagtcc tggaaaaacg
    28261 tggactggtt tcgtgtttgg attattacct tgaacgacat gcgttaaaag ttagttgaac
    28321 cgccgtatgc cgaacggcac gtacggtggt gtgagagggg ctagagatta tcccctactc
    28381 gattttaaat cacatgacgt tcaaaggcat catctgaaat cccttgttcc aagatgagtt
    28441 ttgcccattc tttagcagag aagaggctgt ggtccttgta gtttccgcaa gattcgatgg
    28501 ttgtccctgg gacatcttcc caagtagtag tttcagcgat ttccttgagc gaatccttga
    28561 taacagctgc gattttagca ctggtgtgac gtccccacat aatcatgtgg aagcctgtgc
    28621 ggcaaccaaa tggtgaacag tcaatcatgc cgtcaatgcg ggtacggatg agtttggcta
    28681 agaggtgctc gatagtgtga agaccggcag tagggataga gtcttcgttt ggttgcacca
    28741 agcgaatatc ataattggag atgatgtctc cttttggtcc tgtttcttcc ccaatcaagc
    28801 gaacataggg tgctttgaca atggtgtggt caagttcaaa actttcgaca ataacttctt
    28861 ttgacatggt aaatcctttc agttttcttc tctcattata tcataaaggt tgctcctgag
    28921 acagagagaa aacctctccg aggctggaga ggttgaaatc tttacttacg atataagcgg
    28981 tcgtattggt agtatgggtc aaaggttacg ttgataccca gtttacgaag gacattcttg
    29041 tcttcatcag tcaagatgat ggttgagtgg gcttcgcttc ctttgaggtt gccgagttct
    29101 tccatagcgc gggcagcatc aggattttct gtagctgtga tagcaagtgc aatcaggatt
    29161 tcatttgaat gaaggcgtgg attgcggcta ccgagatgat cgattttaag accttggatt
    29221 ggcttaacaa cttcaggctc gattagtttt acttctttag cgatgtcagc tgattttttg
    29281 atggcgttga tcaaggcagc ggctgtaggc ccaaagagtt ctgagttctt accagtgacg
    29341 atttccccat ttggcaattc aaaggctagg gctggtccac cagtttcttc tgctttttgg
    29401 cgcgcaacga cagcaacctt acgatctgca ggtgtgatac cgaggtcgtt catgagcaac
    29461 tcaattttct tgacggcagc ttcgccaact ttttcagctt tgaagtcaag aactgtttga
    29521 tagtaacggc ggatgatttc ttgtttagaa gcttcgacag cagcctcgtc atctgtaata
    29581 gcgaaaccaa ccatgttgac acccatatct gtcggtgaag cgtatggtga ttttccgaga
    29641 atacgttcca acatgcgttt gagcactggg aagatttcga tatcacggtt gtagttgaca
    29701 gtggtttctc cataggtttg aagatggaag gggtcaatca tgttgacatc atcaaggtca
    29761 gctgtggcag cttcataagc caagttaact ggatgatgaa ggggaagatt ccaaacaggg
    29821 aaggtttcaa atttagcgta gccagatttg atgccattga tttggtcgtg gtacatattg
    29881 gacatacacg ttgccaattt tccagaaccg ggtccaggag cggttacgac aatcaagttg
    29941 cgactggttt tgatgtagtc gtttttgccc atgccttctg gggaaatgat gtgatccata
    30001 tccgtaggat atcctttgat tggataatga agataagaat caattccgtt tttctcaagt
    30061 tggttgcgga aggcatctgc agcgggttgg ccagcgtatt gtgtaatgac aacggaacca
    30121 acaaaaatcc ctaattcatt gaatttgtca atcaaacgaa gaacttcttg gtcataagaa
    30181 atgcctaagt cgccacgtgc tttggaatgt tcaatgttgc tagcattaat ggcaatcaca
    30241 acctcaacct gctctttcaa ttcttgcaag agcttgattt tgttgtcagg ttcataacca
    30301 ggaaggacac gagcagcgtg gaaatcttct aacattttac cgccaaactc taagtagagc
    30361 ttgccgtcaa attggttaat gcgctccaaa atatggtcgc gttgtaaatt caaatactgt
    30421 tcagaactaa aagcttgttt tttcattttt ttacctctgg actctattat aataaaaaat
    30481 tggaagttag gaaactacgg agctaaaaaa gaaattaaaa agattaagca aacgcttgca
    30541 caaaatttta aaaagtgcta tcatatacta tagattatta aaataatgag gtaaacagat
    30601 gcaagaaaaa tggtggcata atgccgtagt ctatcaagtc tatccaaaga gttttatgga
    30661 tagtaatgga gatggagttg gtgatttgcc aggtattacc agtaagttgg actatctagc
    30721 taagctagga atcacagcga tttggctttc tcccgtttat gacagcccta tggatgataa
    30781 tggctacgat attgctgatt atcaagcgat tgcaacgatt tttggaacca tggaggatat
    30841 ggatcaactg attgcggaag ctaagaagcg tgacattcgt atcatcatgg acttggtggt
    30901 taatcatacc tcagatgaac atgcttggtt tgtcgaagct tgtgaaaata ctgacagccc
    30961 tgagcgagac tactatatct ggcgcgatga acccaatgac ctagattcta tctttagtgg
    31021 gtctgcttgg gaatacgatg aaaagtcagg tcaatactat ctccactttt tcagcaagaa
    31081 acagccggat ctcaactggg aaaataaaaa acttcgccag aaaatttatg agatgatgaa
    31141 cttctggatt gataaaggta ttggtggttt ccgtatggat gttattgaca tgattggcaa
    31201 aattcctgac gagaaggtag tcaataatgg tcctatgctc catccctatc tcaaggaaat
    31261 gaatcaggcg acctttggag ataaggatct cttgacagta ggggagactt ggggagcaac
    31321 gccagagatt gccaagctct actctgatcc aaaggggcaa gaattgtcta tggtcttcca
    31381 gtttgaacat atcggtcttc agtatcagga aggtcagcct aaatggcact atcaaaaaga
    31441 gctgaatatc gctaagttaa aagaaatctt caacaaatgg cagacagagt taggagttga
    31501 ggacggctgg aattccctct tctggaacaa ccatgacctc cctcgtattg tctcaatctg
    31561 gggaaatgac caagaatacc gcgaaaaatc tgccaaagcc tttgcaatct tacttcatct
    31621 catgagagga actccttata tctaccaagg tgaggagatt gggatgacca actatccgtt
    31681 tgaaacacta gatcaagtag aagatattga atccctcaac tatgcgcgtg aggctcttga
    31741 aaaaggtgtt ccgattgaag aaatcatgga cagtatccgt gttattggac gtgacaatgc
    31801 ccgtacccct atgcaatggg acgagagcaa aaacgctggt ttttcaacag atcaaccttg
    31861 gttggcagtt aatccaaatt acgagatgat caacgtccaa gaagcgctgg caaatccaga
    31921 ttctattttc tatacctatc agaaactggt ccaaattcgc aaggagaata gctggttaat
    31981 tcgagctgac tttgaattgc ttgatacggc tgataaggtc tttgcttata tacgtaagga
    32041 tggcgaccgt cgcttcctag ttgtggctaa cttgtccaat gaagagcaag acttgacagt
    32101 agaaggaaaa gtcaaatctg tcttgattga aaacacccta gctcaagaag tctttgaaaa
    32161 acaaatctta gttccatggg atgctttctg tgtggaatta ctataaatat tttttgcaga
    32221 aaaatttaaa attgaaatca tataaaaaca agggaggact gtataaaagg cggaaatcct
    32281 ttgtttttta taaccaaggt ttataaactt tcattctcga aattcaatta actttacaaa
    32341 ttcccactat taaggagaaa gaagatgaac ataaagaagc gtgtccttag tgcaggcctg
    32401 acttttgcat ctgctttgct tttagctgct tgcggccaat caggttcaga tacaaaaact
    32461 tactcatcaa cctttggtgg aaatccaact acatttaact atctattaga ctattacgct
    32521 gataatacag tcaattgaaa caagaacaag acaaaagagc ttcgtaaaag gtattgcaac
    32581 ttggtaatac ctttttgagg ttctttttga tatgagccca tgttttctca ataggattgt
    32641 actcaggtga gtagggagga agaggtaaaa gtttatgccc aaactcttcg cataaaagtt
    32701 ctaacttccc cattctatgg aatcttgcat tatccataat aataaccgat ggtgtggtta
    32761 atgttggtaa gagaaacttc tgaaaccaag cttcaaaaaa gtcgctcgtc atcgtctctt
    32821 cgtaagtcat tggagcgatt aactcaccat tcatttgtta gacctgcaac caaagaaatc
    32881 ctctgatatc ttcttccaga tactttgcct cttattaact gactttttaa tgagcgacca
    32941 tattctcgat aaaaataagt atcgaatcct gtttcatcaa tctaaacagg tgataggtgc
    33001 tttaaactat taaaattctt aagaaataag gctacttttt ctgggtcttg ttcatagtag
    33061 gtgtggttct ttttttcgag tgtagcccat agctttgagc gcatagtgga tggtagttgg
    33121 atgacagcca aattcagaag ctatttcagt caaataagcg tctggattgt cagtaagata
    33181 gtttttaagt ctatctctat caacctttct tggttttgtt ccttttactt ggtggtttag
    33241 ctctcttgtt ttctctttta gctttaacca gccataaatg gtattacgtg agatttggaa
    33301 aacgtgtgat gcttctgtta tactacctgt tcgctcacaa taagagagaa cttttttacg
    33361 aaaatctatt gaatatgcca taagaagatt ataccgcatt gtctactata ttata
//
LOCUS       DAVHSI010000019        32862 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.019, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000019 DAVHSI010000000
VERSION     DAVHSI010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32862
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.019"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            62..358
                     /locus_tag="VVR21_001111"
     CDS             62..358
                     /locus_tag="VVR21_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU6055006.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDLVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            479..1423
                     /gene="manA"
                     /locus_tag="VVR21_001112"
     CDS             479..1423
                     /gene="manA"
                     /locus_tag="VVR21_001112"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU6055007.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1414..2919)
                     /locus_tag="VVR21_001113"
     CDS             complement(1414..2919)
                     /locus_tag="VVR21_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEU6055008.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGDFLLIFLISTILIDFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSISLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKDLSNELRPFLFYG"
     gene            3136..3440
                     /locus_tag="VVR21_001114"
                     /pseudo
     CDS             3136..3440
                     /locus_tag="VVR21_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819367.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family DNA-binding protein"
     gene            complement(3469..3924)
                     /locus_tag="VVR21_001115"
     CDS             complement(3469..3924)
                     /locus_tag="VVR21_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6055009.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(3944..5119)
                     /locus_tag="VVR21_001116"
     CDS             complement(3944..5119)
                     /locus_tag="VVR21_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU6055010.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5178..6023)
                     /locus_tag="VVR21_001117"
     CDS             complement(5178..6023)
                     /locus_tag="VVR21_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU6055011.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAENIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6148..6705
                     /locus_tag="VVR21_001118"
     CDS             6148..6705
                     /locus_tag="VVR21_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6055012.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            6724..7191
                     /locus_tag="VVR21_001119"
     CDS             6724..7191
                     /locus_tag="VVR21_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU6055013.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7280..7909
                     /gene="upp"
                     /locus_tag="VVR21_001120"
     CDS             7280..7909
                     /gene="upp"
                     /locus_tag="VVR21_001120"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU6055014.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8083..8673
                     /gene="clpP"
                     /locus_tag="VVR21_001121"
     CDS             8083..8673
                     /gene="clpP"
                     /locus_tag="VVR21_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU6055015.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            8752..9000
                     /locus_tag="VVR21_001122"
     CDS             8752..9000
                     /locus_tag="VVR21_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU6055016.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9101..10261
                     /locus_tag="VVR21_001123"
     CDS             9101..10261
                     /locus_tag="VVR21_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU6055017.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10529..11398
                     /locus_tag="VVR21_001124"
     CDS             10529..11398
                     /locus_tag="VVR21_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6055018.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSNAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11402..12358
                     /locus_tag="VVR21_001125"
     CDS             11402..12358
                     /locus_tag="VVR21_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU6055019.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12358..13122
                     /locus_tag="VVR21_001126"
     CDS             12358..13122
                     /locus_tag="VVR21_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055020.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13122..13832
                     /locus_tag="VVR21_001127"
     CDS             13122..13832
                     /locus_tag="VVR21_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055021.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14191..14847
                     /locus_tag="VVR21_001128"
     CDS             14191..14847
                     /locus_tag="VVR21_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6055022.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            14955..16050
                     /gene="prfB"
                     /locus_tag="VVR21_001129"
     CDS             join(14955..15026,15028..16050)
                     /gene="prfB"
                     /locus_tag="VVR21_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU6055023.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16068..16760
                     /gene="ftsE"
                     /locus_tag="VVR21_001130"
     CDS             16068..16760
                     /gene="ftsE"
                     /locus_tag="VVR21_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU6055024.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            16753..17679
                     /locus_tag="VVR21_001131"
     CDS             16753..17679
                     /locus_tag="VVR21_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055025.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            17965..20145
                     /locus_tag="VVR21_001132"
     CDS             17965..20145
                     /locus_tag="VVR21_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU6055026.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIVVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20197..21012
                     /locus_tag="VVR21_001133"
     CDS             20197..21012
                     /locus_tag="VVR21_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU6055027.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            21152..22495
                     /locus_tag="VVR21_001134"
     CDS             21152..22495
                     /locus_tag="VVR21_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6055028.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLSGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRADRKAKRQTF"
     gene            22710..23900
                     /locus_tag="VVR21_001135"
     CDS             22710..23900
                     /locus_tag="VVR21_001135"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU6055029.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24453..25388
                     /locus_tag="VVR21_001136"
     CDS             24453..25388
                     /locus_tag="VVR21_001136"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU6055030.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25422..26459
                     /locus_tag="VVR21_001137"
     CDS             25422..26459
                     /locus_tag="VVR21_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU6055031.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            26632..27237
                     /locus_tag="VVR21_001138"
     CDS             26632..27237
                     /locus_tag="VVR21_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU6055032.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQNTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27393..27923
                     /locus_tag="VVR21_001139"
     CDS             27393..27923
                     /locus_tag="VVR21_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU6055033.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            27944..29029
                     /gene="rlmN"
                     /locus_tag="VVR21_001140"
     CDS             27944..29029
                     /gene="rlmN"
                     /locus_tag="VVR21_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU6055034.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            29029..29511
                     /locus_tag="VVR21_001141"
     CDS             29029..29511
                     /locus_tag="VVR21_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU6055035.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29513..31054
                     /locus_tag="VVR21_001142"
     CDS             29513..31054
                     /locus_tag="VVR21_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6055036.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31110..31913)
                     /locus_tag="VVR21_001143"
     CDS             complement(31110..31913)
                     /locus_tag="VVR21_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU6055037.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(31996..32208)
                     /locus_tag="VVR21_001144"
     CDS             complement(31996..32208)
                     /locus_tag="VVR21_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055038.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
BASE COUNT         9949 a         6132 c         7170 g         9611 t
ORIGIN      
        1 actattatat aatgcttttt gattttagtt tagtattatc gtagaaaatg gactcggtgc
       61 tatggataca ccggatgaga atggttatgt agcagataac tatcggatta cttacttaga
      121 ggcccacatc aaggccatgc gagatgccat ttaccaagac ggggttgact tgcttggtta
      181 tacgacttgg ggctgtatcg atctggtttc agctggcaca ggggaaatga ataagcgcta
      241 tggctttatc tatgtagatc gagataatgt aggaaacgga gctctcaaac gtagcaagaa
      301 gaagtccttc tattggtaca aggatgtcat tgatagcaat ggtgcaagca tcgggtagag
      361 cacatttgtt tactattttt ataaaatctt ctccctgctt tataagatgt aaaaaagagt
      421 tcaattcgaa ctcttttttt gctataatga ggggagaaaa atcagacagg agatcgacat
      481 gtcagaacca ttatttttac aatcagttat gcaagaaaaa atctggggtg gagccaagct
      541 acgtgatgag tttggctacg acatcccaag tgaaaaaatc ggagaatatt gggccatctc
      601 agcccatcca aatggagtct ctaaagttgc caatggtcgt tacgagggaa cagatcttgc
      661 tactttgtat gcggaacacc gtgaattatt tggcaatcgt ccagaacctg tatttccact
      721 tttgaccaag atcctcgatg ccaacgactg gctcagtgtc caagttcacc cagacgatgc
      781 ttatggactc gagcatgaag gcgaactcgg aaaaacagaa tgctggtaca tcatcgctgc
      841 ggatgaaggt tcagagatta tctacggtca caatgccaag tcaaaagaag aactccgcca
      901 gcaaatcgag gataagaact gggatgcgct gttgacaaaa gtgccagtta aagcaggaga
      961 tttcttctat gtaccaagcg gtaccatgca cgctatcggg gcgggtatct tgattcttga
     1021 aacccagcag tctagcgata ccacttaccg tgtctatgac tttgaccgta aggatgacaa
     1081 gggcaattta cgtgaacttc accttgaaaa atctatcgat gtcttgaaca ttggtgaacc
     1141 cgcaaatagc cgtccagtga caatcaaagc agatgatcta cgttccactc tccttgtatc
     1201 caatgatttc ttcgcagttt acaaatggga aattactgga aaagttaact ttgaaaagac
     1261 agctgactac agcttgttga gtgtcttggc tggtcaaggt caactaactg ttgacgggaa
     1321 aaactatcca atccaaaaag ggagacactt tatcctacca agtgatgttg aagcttggac
     1381 tctggaaggg caagatttag aattaattgt tagtcatcca taaaaaagaa agggcctgag
     1441 ttcattactc aagtcctttt gattacataa attgggcgat gaagaccacg atgatgattg
     1501 gaatgacgga acgaagaaac gaagaaggaa gagccagact tggaacagtc cttgtttcca
     1561 tgctctttca tcgagatgga gttcctccat tgcaagagcc tttttaaaga tatagcctgt
     1621 aaaaagtgaa aggtagagag ctccaaatgg catgaggaga ttggaaacca agaagtccat
     1681 agcgtcaaag aaggtcttac caaaaatgtg aacatccgcc atgacaccgt aagatagggc
     1741 tgaaggaatg ccaaagacaa aggtcaaaat tcctaaaata acactccatt tggcacgttt
     1801 gctgttatcc tggttggtga tattgcccac attgatctcc agcatcacga cagaagaagt
     1861 gacagtcgca aagaggaaga ggacgtagaa aatggttcca aaaggcatct tgtcaaagag
     1921 ttgaggcaag acgataaaga gcaagctcgg tcccccttca gactggatat tgaaggggga
     1981 tcgagcttgg aaaatggcta gacctgccat gatggatatc gagatattca tggctacgat
     2041 ggagattcct gactggacta gattggtttt cttgtccaag taagaagcat aggtcaacat
     2101 gactgtaacc cctagtgaga gggcaaagaa agattgtccc agagcataga ggagaccagc
     2161 gctagtcagt tttgaaaagt ctggtttgag gaagtaaaga accccttcca tggcatttgg
     2221 caaactgata gagcgaccga tgataacaac aaagatgata aagagcaggg gcatcatgac
     2281 tttcgaagct ctttcaatcc ctttttgaac cccacgtgat acaataaaga tatttaataa
     2341 gataaaggct gcttgagcta ctagggcaat ggctggattt gaaatgattg aagtaaataa
     2401 ctgagcataa tcacccgttc caccaagttg gaacaatttc ccaaactcaa tacctagata
     2461 gactagaatc catcctccga taacactgta aaaagataag aggataaaga gggcaaaggc
     2521 gccaatccaa ccgataaagt tgtacttgtt attcttgccc agttttccaa aggttttgat
     2581 agcggaaacg ccagcactac ggccaagggc aaactcagcc agcaggagag ggaaatcgat
     2641 taaaatagtg gaaatgagaa agattagtaa aaagtctcca ccgccattag cagcagtcat
     2701 gtagggaaac ttccaaacgg aaccaagccc gatgaccgag ccagcagatg ctagaataaa
     2761 gccaagtttc gacccccatt gtgatttttc tgacatagtt aaactctgat ctcctttttc
     2821 aaaataagaa aaagctactt gagttgtcaa atagccttct gtttgattga tagacttgac
     2881 tatcctatta tgttttctaa ggtctgtcaa gaaaaccatt ttcaagtttt cacacctttc
     2941 tcaaaaacgc ttgactctga cctaagggga ggggttatac tatcattgta aggaggaaat
     3001 catgtaccat ataaaagaag ctgcgcagct ttcaggtgtc tctgtcaaga ccctgccctg
     3061 catcactatg acaagatagg actcttggtc cccttaaagt cggaaaacgg ctatcgaacc
     3121 tatagtcaag aggatttgga acgccttcag gtcattcttt actacaaata tctaggcttt
     3181 tctttagaga aaatagaaga gctgttaaag gaagaaagga cagatttatt gccccattta
     3241 actaggcagt tggactatct aactcgcgaa aggcaacatc tggatacctt gatttccacc
     3301 ttgcaaaaaa ctattcaaga acaaaaaaag gttacgtcta caacccagag tttaaggaaa
     3361 acattgacaa gtttggttct gaaacagccc agtacacgtc agatgccatt gcggcttacg
     3421 ttcagacaaa tgcagaataa ataggctagg aatttcctag cctatttttt acttcaaatc
     3481 ataaagccag tcgtcaccgt ttttgtagta aaagaattca ctgagatctt cttctagaaa
     3541 cacacgaagc atatcagaca tatcatcggt tgcaagtttt agatgagaaa gattttcaaa
     3601 gtcctcccac caaactttcc cttcgtctga agactggagt tcaccagtaa agtgttctgt
     3661 cttgtaaaaa aggacgacat aacgataatc cttgtcgtca taccagtttt tgataccaca
     3721 gagttggggt ttggaaatga tcagaccagt ttcttctttc acttcacgaa tgacagcatc
     3781 gacaaaggat tcgccacgtt caacatgacc accaggaaaa gtaatgccag gccagtcggg
     3841 actaactcgg tcttggacca ggaccttatc tccgttttta atcatacaca tgttaacaaa
     3901 ttcgactgcc tctcttctgt tcattcttca caacctttaa tctttaatca taatgcagac
     3961 ttcccgccac ccagccggta cagagggcag aagtgatgtt aaaaccaccc gtgtgggcat
     4021 tgatatccat aacttcgcct gcaaagtgga ggccaggtac cagcttactt tcaagggttt
     4081 taggattgat ttccttgaga ctgactccac ccttggtaac aaaggacttt gcaagggaca
     4141 tttttccagt tacaggaatt ttaagttctt taatggactg gacaagttgt tctcgttcct
     4201 tttcagtcag ttgtttgact ttttcaggat atccttgtac aaaaaattcg gccaagcgtt
     4261 ctggtaacaa ggtttttaaa gcgtttttca aggatttttc ccgattttct tctagaaatg
     4321 taaccaagtc cttctcagaa agttgaggca aaacatcgag tgagagaacc tccccacctt
     4381 tgacaaagct agacatgcgt agggcagcag gacctgacaa accaaagtgg gtaaagagta
     4441 aatcatgagt gatgacatgc ttaccataac ttagggtcac atcgtccaga gaaatccctt
     4501 gtaaggcttt atgtggaaaa tctgttaata aaggactttc agcagcctca agatcggtga
     4561 tggtatgctt aaaatggcga gcaatctcgt gaccaaaacc agtcgaacca gtcgaaggat
     4621 aagacttacc acctgttgtg acaatgagtt tctcacaagt gaaggtttga tccgctgact
     4681 taaggacaaa ctggtcatct acttttttaa cagaaacgat ttctatttga gtagcaactt
     4741 gaccacctag ttcggtgatt ttcttttcca aagcttcgat aatagtccga gacttgtcac
     4801 tggctggaaa gacgcgtccg tggtcttcga ccttaagttt aacaccattt tctgtaaaaa
     4861 agttgatgat gtcatgatta tcgaactggg agaaaacact gtaaagaaag cgtccgtttc
     4921 caggaattcc agctagcagg ttgtctaagc taccattgtt ggtcacattg caacgtcccc
     4981 caccagtccc agctaatttt tttccaagtt tccgattttt ttcgatgagg agggttttct
     5041 gtccataaaa gctactggaa atcgtagcca tcataccagc aggtccccca ccgatgacaa
     5101 tagtatcaaa atgtttcata gctctattgt accacaaaaa aacaagagat gatggtcaca
     5161 tcttgtcaag aatgcaatta atcaatttca tagcccatca gcaaaccgcc ctcttctgca
     5221 tagaaactgc agagaccaga ggttggtaga attttaatat ccgcttgtgg gaaggtttca
     5281 cggattcgct ctgagagctg ttgacaacat ttttcgttat tgcgttgggc catgacaata
     5341 cggccaccag catatccagc ttttactaac tcatcatagg cagcttgaac tgatttcttt
     5401 gatccccttg ctttttgtag caattcgaga gttccagttt cactagcttt tccgaccata
     5461 cgaatgttga gaaggccaac gaccgtaccg ataagcttgc tcaaacggcc gttcttcacc
     5521 aagttatcga ctttggctag gacaaagagc aacttagttt tttcttgata ggcggtgata
     5581 gcttcaacca cttcttcaaa agacaagcct tggtcaatca agtcattcaa tttttctacg
     5641 agtaggtcaa cttcaccacc agcagataaa ctatcaatca catgaatctt agtgtcagga
     5701 tggtcttcca gataaatatt ctttgctagt tgagcactat tgtgactgcc agaaagggta
     5761 cctgtgatgg ttactaggaa aatgttttcg gcaccttcaa atgctcgcaa atagtcatct
     5821 gggcttggac aagctgattt tgaagcttct gcagttgcat acatggtttc catcatttgg
     5881 tcaatatcga gactggcgtc atcaacaaag acctgatcag ctacttgaat ggttaagggg
     5941 acacttacaa aggttgtgtt aatagctggt gttggcagtt gacgataatc acaaccagag
     6001 tcagcaataa tcttccaagt catagaaatt ctccatcttt gtcagttata cattgacaaa
     6061 ggttctgtct ttttttacaa ttatatcatg aaaactcttg aaacaaaagc atcatccgtc
     6121 tgttgtgaca agtagaaaga aaatgttatg tctgaacgta gaatctctga aaagtctctt
     6181 gaaaatctca gaaaatcaaa ccaagaatcc aatttattaa ccagagaagc cattgaaaca
     6241 gccctcttgc aactcttgga aaaaaaggag ctgaccaaga ttagtatttc tgaattggtc
     6301 aaacgtgcag gtgtttcgcg tgcggccttt tatcgcaatt atgactccaa agaggaaatt
     6361 ttagagagcg tctttaaacg aactgtccac aatattatgg aacagctgca tcattacgat
     6421 ttaaagacag acctttattt ggtttgggtt caccttttcc gggaggccag aaaggaagct
     6481 agagtgattc aattggcctt ggattaccat ctggaaaaaa tctttgtcca agccatgcag
     6541 gaatttctag aaaaatacca tgggaaatca aaaggtgtca gctcttatct tcattccttc
     6601 tggagctcag ccatcgtctc tgtccttcta aaatggatca aggatggcat gaaggtacca
     6661 gctgaaaaga ttgcagattt aggtttacca ttttttaaaa aatagagaaa aaggagaaaa
     6721 gagatgactg aaaaaagact ggcctgggat gagtattttg cagcccaagc tctactaatt
     6781 gcgaatcgtt ccacttgtaa acgtgctaaa gtgggcgcga ttctggtaaa agataataag
     6841 gttatttcca ctggttacaa tggttcggtg tcagggactg agcattgtat tgatcacgaa
     6901 tgtttggtca ttgaaggcca ctgcgttcgc acccttcacg ctgaggtcaa tgctatcctt
     6961 caaggtgctg agcgtggtgt tcccaaaggc tttacagcct atgtaaccca ttttccttgt
     7021 ctcaactgta caaaacaatt gcttcaggtc ggctgcaagc gcgtggttta tatcaaccag
     7081 taccgaatgg acgactacgc ccaatacctt tatcaagaaa aagggacaga attgacccat
     7141 ttaccacttg agacagtaca gacagctctt aaagaggctg atctaatgta aaaattatca
     7201 aaaataaatg gtttagaaag atttttaaac cgttttttgg tataataaga agaataaatt
     7261 gaaagaagga attccaaaaa tgggaaaaat tgaagttatt aatcacccac tgattcaaca
     7321 caaattgtca attttgcgtc gtacagatac ttctacaaaa gcttttcgtg agctagtaga
     7381 tgagattgca atgttgatgg ggtatgaagt acttcgtgat cttccactag aagatgtgga
     7441 aatcgaaaca ccaattacaa aaacagttca aaaacaattg gcaggtaaga aattggccat
     7501 cgtcccaatc ttgcgtgcag gtatcgggat ggttgatggt ctcttgagct tggttccagc
     7561 tgctaaagtt ggccacatcg gtatgtaccg tgatgaagaa acacttcaac cagttgaata
     7621 cttggtgaaa ttgcctgagg acattgacca acgtcaaatt tttgtagtag acccaatgtt
     7681 ggcaacaggt ggctcagcaa tcttggctgt tgattctctt aaaaaacgtg gcgcatcaaa
     7741 tatcaaattt gtctgccttg tatctgctcc agagggtgta aaagcccttc aagaagctca
     7801 tccagatgta gaaatcttta cagcagcctt ggatgaacgt ttgaatgaac acggttatat
     7861 cgttccaggt cttggagatg ctggagaccg cttgttcggt acaaaataag atcgaaaaga
     7921 agaatgactt ggaaaagtat ttctagtcac gaaaggaggt tgggtttttg tttctgtcta
     7981 atgaaagcag agcaaaaatt tgaccttttt tgaccaagat attataatag tcttatcttc
     8041 agtcatttga ccaacaaaat taaaactcaa aaggagaaat gaatgattcc tgtagttatt
     8101 gaacaaacaa gccgtggaga acgttcttac gatatttact cacgtcttct caaagaccgc
     8161 atcattatgc tgacaggtcc ggttgaagac aatatggcta actctgttat tgcccaattg
     8221 cttttcttgg atgcccaaga tagtacgaaa gatatttacc tttatgtcaa tacaccaggt
     8281 ggttctgttt cagctggttt ggcaatcgta gataccatga actttatcaa ggcagatgtc
     8341 caaaccattg ttatgggaat ggctgcatct atggggactg tcatcgcatc aagtggagca
     8401 aaaggcaaac gtttcatgct tccaaatgct gaatacatga ttcaccaacc aatgggcggt
     8461 acaggtggtg gtacccaaca aactgatatg gctatcgctg cagaacactt gctcaaaact
     8521 cgtaatacct tggaaaaaat cttggctgaa aattcaggtc agtcaatgga aaaagtccat
     8581 gcagatgcag aacgtgataa ctggatgagc gcccaggaaa cacttgaata tggctttatt
     8641 gatgaaatta tggccaacaa ttcattgaac taatgatgat agaaggcaaa ctcgactggg
     8701 tttgcttttt ttggtataat agggagagat ttcttagaaa gaggatttat catgtttgaa
     8761 aaagtcaatc gctctggctt gattatctat ctttactata atcgtgatgc caaaaaactg
     8821 caggattatg gagatattac ctatcattcc aagaaacatc gttacttaca actctatgtt
     8881 ccaactcaag aagtggagca attggtcgga cgcttgagca aggaaaaatt tattaaaaaa
     8941 gttagggttt gtcatatcca agagttggaa acaccctttg tgggcaatct ttatcgatag
     9001 gaaaacgtta tcatcgaaaa agttcaagga aaacattgac aattttctga taattcggta
     9061 tattcttaac agactattta agaaataagg agacaaaaag atgaagaaaa aatttgccct
     9121 atcgtttgtg gcgcttgcaa gtgtagcact tcttgcagcc tgtggagaag tgaagtctgg
     9181 agcagtcaac actgctggta actcagtaga ggaaaagaca attaaaatcg ggtttaactt
     9241 tgaagaatca ggttctttag ctgcatacgg aacagctgaa caaaaaggtg cccaattggc
     9301 tgttgatgaa atcaatgccg caggtggtat cgatggaaaa caaatcgaag tagtcgataa
     9361 agataataag tctgaaacag ctgaggctgc ttcagttaca actaaccttg taacccaatc
     9421 taaagtatca gcagtcgtag gacctgcgac atctggtgcg actgcagctg cggtagcgaa
     9481 cgctacaaaa gcaggtgttc ccttgatctc accaagtgcg actcaagatg gattgactaa
     9541 aggtcaagat tacctcttta ttggaacttt ccaagatagc ttccaaggaa aaattatctc
     9601 aaactatgtt tctgaaaaat taaatgctaa gaaagttgtt ctttacactg acaatgccag
     9661 tgactatgct aaagggattg ccaaatcttt ccgcgagtca tacaagggtg aaatcgttgc
     9721 agatgaaact ttcgtagcag gtgacacaga ctttcaagca gcccttacaa aaatgaaagg
     9781 gaaagacttt gatgctatcg ttgttcctgg ttactataat gaggctggta agattgtaaa
     9841 ccaagcgcgt ggcatgggaa ttgacaaacc aatcgttggt ggtgatggat tcaacggtga
     9901 ggagtttgta caacaagcaa ctgctgaaaa agcatcaaac atctacttta tctcaggctt
     9961 ctcaactact gtagaagttt cagctaaagc taaagccttc cttgacgctt accgtgctaa
    10021 gtacaatgaa gagccttcaa catttgcagc cttggcttat gattcagttc accttgtagc
    10081 aaacgcagca aaaggtgcta aaaattcagg tgaaatcaag gataaccttg ctaaaacaaa
    10141 agattttgaa ggtgtaactg gtcaaacaag cttcgatgca gaccacaaca cagtcaaaac
    10201 tgcttacatg atgaccatga acaatggtaa agttgaagca gcagaagttg taaaaccata
    10261 atagaaaaat gttgaaatag ggaatgagcc tttgactcac tccctgtttc gatatttaat
    10321 actcttcgaa aatctcttca aactgcgtca acgtcgcctt ggattatata tgtgactgac
    10381 ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag caacctgtgg ctagtttcct
    10441 agtttgctct ttgattttca ttgagtataa gaacctatca aaaagtgagg gaaacccctc
    10501 ggaattataa atagaaagag tgaatcttat gctccaacaa ctcgtaaatg gtttgattct
    10561 aggtagtgtt tacgcgctgt tagccctagg atataccatg gtttacggaa ttatcaagct
    10621 catcaacttc gcccatggtg atatttatat gatgggagcc tttatcggtt atttcttgat
    10681 caattctttc caaatgaatt tctttgtagc gcttattgta gctatgctag cgacagctat
    10741 tcttggtgtc gtgattgagt ttcttgctta ccgacctttg cgccactcta ctcgtattgc
    10801 tgttttgatt acggctattg gggtttcttt cctattggag tatggaatgg tctatctggt
    10861 tggtgccaat acccgtgcct tccctcaagc gattcaaaca gttcgatatg atttgggacc
    10921 aattagctta acaaatgtgc agttaatgat tttggccatt tccttgattt tgatgatttt
    10981 gttacaagtc attgtccaaa agactaagat ggggaaagcc atgcgtgcag tatcagtaga
    11041 tagcaacgcg gcgcaattga tggggatcaa tgtaaaccgt acgattagct ttaccttcgc
    11101 tttgggttct gctcttgcgg gtgcggctgg tgttctgatt gctctttatt ataactctct
    11161 tgagcctttg atgggggtta ctccaggtct taaatctttc gttgccgcag tacttggtgg
    11221 tatcggaatt attcctggtg cggctcttgg tggctttgtg attggtctat tggaaacctt
    11281 tgcgacagcc tttgggatgt cagatttccg tgatgccatt gtttatggaa tcttgttgtt
    11341 gatcttgatt gtccgcccag ctggtatcct tggtaagaat gtgaaagaga aggtgtaaac
    11401 gatgaaggaa aatttaaaag ttaatattct atggttactc cttttgttag ctggctatag
    11461 cttgattagt gtactggttt cagtcggagt acttaatcta ttctatgtac agattttaca
    11521 acaaattgga attaatatta ttttggctgt tggtctcaac ttaatcgttg gtttttcagg
    11581 acaattttca cttggtcatg ctggtttcat ggcgattggt gcctatgcag cagctattat
    11641 tggttctaaa tcaccaacct acggtgcctt ctttggagct atgcttgtag gggctttgct
    11701 ttcaggagca gttgccttac ttgtcggcat tccaaccttg cgcttgaagg gggactatct
    11761 tgcggtagca actctgggtg tttctgaaat tatccgtatc tttatcatca atggtggaag
    11821 tcttacaaat ggtgcggcag gtatcttagg gattcctaac tttacaactt ggcaaatggt
    11881 ttacttcttt gtcgtgatta caaccattgc aaccttgaac ttcttgcgta gcccaattgg
    11941 tcgttcaacc ctctctgttc gtgaagatga aatcgctgct gagtcagttg gggttaatac
    12001 gactaaaatt aaaatcatcg cttttgtctt tggtgccatt actgcaagta ttgctgggtc
    12061 acttcaggca ggatttatcg ggtctgttgt accgaaagat tacaccttca tcaactcaat
    12121 caacgttttg attattgttg tatttggtgg actcggttcc attacaggtg cgattgtttc
    12181 ggctattgtt ctgggaattt tgaatatgct tctccaagat gttgctagtg tgcgtatgat
    12241 tatttacgct ttggccttgg tattggtaat gattttcaga ccaggtggac tccttggaac
    12301 gtgggaactg agcctatcac gtttctttaa aaaatctaag aaggaggaac aaaactaatg
    12361 gcattacttg aagtaaaaca gttaaccaaa cattttggtg gtctaacagc tgttggagat
    12421 gtgactcttg aattgaacga aggggaactg gttggattaa tcggtccaaa cggagctggg
    12481 aaaaccaccc ttttcaacct tttgaccggt gtttatgaac caagcgaggg aacagtaacc
    12541 ctagatggtc accttttgaa tgggaaatca ccttataaga ttgcctcttt gggacttgga
    12601 cgtactttcc aaaatatccg tctctttaaa gatttaacag ttttagataa tgttttgatt
    12661 gcttttggaa accatcacaa acagcatgtt tttactagtt tcttacgctt accagctttt
    12721 tacaagagtg aaaaagaatt aaaggctaaa gctttggaat tgttgaaaat ctttgattta
    12781 gatggtgatg cagagactct tgctaaaaat ctttcctacg gacaacaacg tcgtttggaa
    12841 attgttcgtg cccttgctac ggaacctaaa attctcttct tagatgaacc agcagcaggt
    12901 atgaacccac aggaaacagc cgaattgact gagttaattc gtcgtatcaa agatgaattt
    12961 aagattacaa tcatgttgat tgaacacgat atgaatctgg tcatggaagt aacagaacgt
    13021 atctacgtac ttgaatatgg ccgtttaatt gctcaaggaa ctccagacga aattaagacc
    13081 aataaacgcg ttatcgaagc ttatctagga ggtgaagcct aatgtctatg ttaaaagttg
    13141 aaaatctttc tgtgcattac ggtatgatcc aagcagtccg tgatgtaagc tttgaagtta
    13201 atgaaggaga agttgtttcc cttatcggtg ccaacggtgc aggtaagaca actattcttc
    13261 gcaccttgtc aggtttggtt cgaccaagtt caggaaagat tgaattttta ggtcaagaaa
    13321 tccaaaaaat accagctcag aaaatcgtgg caggtggtct ttcacaagtt ccagaaggac
    13381 gccacgtctt tcctggcttg actgttatgg aaaatcttga aatgggagct ttcttaaaga
    13441 aaaatcgtga agaaaatcaa gctaacttga agaaggtttt ctcacgcttt cctcgtcttg
    13501 aagaacgtaa gaaccaagat gcagctactc tttcaggagg ggaacaacaa atgcttgcca
    13561 tgggacgcgc tcttatgtca acaccaaaac ttcttctttt agatgaacca tcaatgggac
    13621 ttgccccaat cttcatccaa gagatttttg atatcattca agatattcag aagcaaggaa
    13681 caaccgtcct cttgattgaa caaaatgcca ataaagcact tgcaatctct gaccgaggat
    13741 atgtattgga aacaggaaaa atcgtcctat caggaacagg aaaagaactc gcttcatcag
    13801 aagaagtcag aaaagcatat ctaggtggct aaaacaatcc agtggattgt tttagtcggc
    13861 agatgaagat tacgaagtaa tcatcaatat agtccggggg ccctttttag tcggtggatg
    13921 aagattgcga agcaatcatc aaatccagag gattgtttta gccggtagat tgagattgca
    13981 aacaaatctg catctacatt gaaagcttaa tttctaataa ttgaaaaaat cgaatgaaaa
    14041 gtttcttacc ttcattcaca gagctcgatt ttagagctct ttttgctagc ttattcatac
    14101 ttttctaaat tttgaaaaag aaatgtaagc gtttgataga tttgcaaaaa gattgtataa
    14161 tagggataag aatagaaaag gagaagtctc atggcagtta aagattttat gacccgcaag
    14221 gtagtttata ttagtccaga tacaacagta tctcatgcag cagatttgat gagagagcaa
    14281 gaattgcatc gcttgcctgt tatcgaaaat gatcaattgg ttggtttggt gactgaggga
    14341 accattgcac aagcaagtcc atctaaagca acaagtcttt ctatctatga gatgaattat
    14401 cttctgaata agacaaaagt aaaagatgtc atgattcgcg atgttgtcac tgtctcaggc
    14461 tatgctagtc tagaagatgc aacttatctg atgttgaaaa ataagattgg tattctccct
    14521 gtcgtagata accatcaagt atacggagtt attactgacc gtgacgtttt ccaagccttt
    14581 cttgaaattg caggttatgg cgaagaaggg attcgtgtac gctttgttac agaagatgaa
    14641 gttggtgttc ttggaaaaat tgtttctttg attgtagaag aaaatttgaa tatctcccat
    14701 acagtcaata ttccgcgtaa ggatggtaag gtgattatcg aagtgcaaat cgatgaatca
    14761 attgatttac cagccttgag agaaaaattt gaagcaaatg gtattcaagt ggaagaaatc
    14821 gctcgcactt cagcaaaagt cttgtaagaa gggaagtcca aaggcttctt ttttcatgaa
    14881 aaggggatta gagcaaaaga tggaaagaaa tgataaaata tgctataatg aaataatgta
    14941 aaaaaggagt atttatggac atttcagtaa ttcgtcagaa aattgacgca aatcgtgaaa
    15001 aattagcttc tttcaggggg tctctttgac ctcgaagggc tagaggaaga gattgccatc
    15061 ttggaaaaca agatgacaga acctgatttt tggaacgata atattgcggc ccaaaaaacg
    15121 tcgcaagaat tgaatgaatt aaaaaacact tacaatacct tccataagat ggaagagttg
    15181 caggatgaag tcgaaatttt attggatttt ttggctgaag acgagtcagt gcatgatgaa
    15241 ctggtagcgc aattagccga acttgataag ataatgacca gctacgagat gactctactc
    15301 ttgtcagaac cttatgacca caacaatgcc atcttggaaa tccatccagg ttctggtggt
    15361 actgaggcgc aggactgggg tgatatgttg cttcgtatgt atactcgtta tggtaatgct
    15421 aaaggcttta aagtggaagt gttggattac caagcaggtg atgaggctgg tattaagtcg
    15481 gtaactttat catttgaagg gcctaatgcc tatggtctcc tcaagtcaga aatgggtgtt
    15541 caccgcttag tgcgaatctc accatttgac tctgccaaac gtcgccatac ctctttcaca
    15601 tctgtagaag tgatgccaga attggatgat actattgaag tggaaatccg tgaagatgat
    15661 atcaagatgg ataccttccg ttcaggtggt gccggtggac aaaacgtcaa taaggtttca
    15721 acaggtgtac gtttaaccca cattccaact ggaattgttg tccaatcaac agtggatcgt
    15781 acccagtatg gaaatagaga tcgtgccatg aagatgttgc aggctaagct ctatcaaatg
    15841 gagcaagata agaaggctgc ggaggtagat tctctcaaag gtgagaaaaa ggagatcact
    15901 tggggaagcc aaatccgttc ttatgtcttc acgccttata ctatggtaaa agatcaccga
    15961 actagctttg aggttgctca ggtagataag gttatggatg gggacctaga tggttttatc
    16021 gatgcttatc tcaagtggcg aattagctaa gatagaaagg aactcacatg tcaattattg
    16081 aaatgagaga tgtcgttaaa aaatacgaca acggaacgac tgctctacgc ggtgtttcgg
    16141 tcagcgttca accgggggaa tttgcttaca tcgtaggacc ttcaggagca gggaagtcaa
    16201 cttttattcg ttctctgtat cgtgaagtaa aaatcgataa aggaagtcta tcagttgctg
    16261 gttttaatct ggttaagatc aaaaagaaag atgtcccgct tctacgtcgt agtgttgggg
    16321 ttgtcttcca agattataaa ttgttaccaa agaaaactgt ctatgaaaat attgcttacg
    16381 ctatggaagt aatcggggaa aatcgccgta atatcaaaag acgagtgatg gaagttttgg
    16441 acttggttgg attgaagcat aaggttcgtt ctttcccaaa tgaactctca ggtggggagc
    16501 aacagcgaat tgcgattgcg cgtgcaattg taaataatcc caaagtattg atagctgatg
    16561 agccaacagg aaatctggat ccggataatt catgggaaat tatgaatctc ttggaacgga
    16621 ttaacctaca aggaacaact attttgatgg cgactcataa tagccagatt gtaaatacct
    16681 tgcgccaccg tgtcattgcc attgaaaatg gccgtgtcgt tcgtgacgaa tcaaaaggag
    16741 agtatggata cgatgattag tagatttttt cgccatttat ttgaagcctt aaaaagtttg
    16801 aaacgaaatg gttggatgac agtagctgct gtcagttcag tcatgattac tttgaccttg
    16861 gtggcaatat ttgcatctgt tattttcaat acagcgaaac tagctacaga tattgaaaat
    16921 aatgtccgtg tagtagttta tatccgaaag gatgtggaag ataatagtca gacaattgaa
    16981 aaagaaggtc aaactgttac aaataatgac taccacaagg tatatgattc tttgaagaac
    17041 atgtctacgg ttaaaagtgt taccttttca agtaaagaag aacaatatga aaaattaacc
    17101 gagataatgg gagataactg gaaaatcttt gaaggagatg ccaatcctct ctatgatgcc
    17161 tatattgtag aggcaaacac tccaaatgat gtaaaaacta tagccgaaga tgctaaaaaa
    17221 attgaaggtg tctctgaggt tcaagatggc ggtgccaata cagaaagact cttcaagtta
    17281 gcttcattta tccgtgtttg gggactaggg attgctgctt tgttaatttt tatcgcagtt
    17341 tttttgattt caaataccat tcgtattacc attatttccc gcagtcgcga aattcaaatc
    17401 atgcgcttgg tcggagctaa aaacagttat atccgtggac cgttcttgtt agaaggagcc
    17461 tttatcggtt tattgggagc tatcgcacca tctgttttgg tctttattgt ttatcaaatt
    17521 gtttaccaat ctgtcaacaa atcgttggta gggcaaaatc tatccatgat tagtccagat
    17581 ttatttagtc cgttgatgat tgccctacta tttgtgattg gggttttcat tggttcattg
    17641 ggatcaggaa tatccatgcg ccgattcttg aagatttagg taaaatagct gcttttatga
    17701 ggagattgca aaatctcctt ttttgctaca agagtttttg aaaagagatg cgcagaagaa
    17761 aagagcttcc aaagaagtcc cccagagaag acttcttgat ggctaatttg aacttgaaat
    17821 ttggcgcact agaaattttt tagaaaaaag tgtaattttt ttataaaagc ctttacaaaa
    17881 aaaattaaag tggtataatt aaatcataga aagtgcaaac gttttcgtaa aacgtttgcc
    17941 taaataaaaa taaaggagat ttgaatgatg aaagatacat tcaaaaatgt cttgtctttc
    18001 gaattttggc aaaaattcgg taaggctttg atggtagtta tcgtggttat gccggctgct
    18061 ggtttgatga tttcaatcgg taagtctatc gtgatgatta acccaacctt tgcaccactt
    18121 gtcatcacag gtggaattct tgagcaaatc ggttgggggg ttatcggtaa ccttcacatt
    18181 ttgtttgccc tagccattgg aggaagctgg gctaaagaac gtgctggtgg tgctttcgcc
    18241 gctggtcttg ccttcatctt gattaaccgt atcactggta caatctttgg tgtatcaggc
    18301 gatatgttga aaaatccaga tgctatggta actactttct ttggtggttc aatcaaagtt
    18361 gctgattact ttatcagtgt tcttgaagct ccagccttga acatgggggt attcgtaggg
    18421 attatctcag gttttgtagg ggcaactgct tacaacaaat actacaactt ccgtaaactt
    18481 cctgatgcac tttcattctt caacgggaaa cgtttcgtac catttgtagt tattcttcgt
    18541 tcagcaatcg ctgcaattct acttgctgct ttctggccag tagttcaaac aggtatcaat
    18601 aatttcggta tctggattgc caactcacaa gaaactgctc caattcttgc accattcttg
    18661 tatggtactt tggaacgttt gctcttgcca tttggtcttc accacatgtt gactatccca
    18721 atgaactaca cagctcttgg tggtacttat gacattttaa ctggtgcagc taaaggtact
    18781 caagtattcg gtcaagaccc actatggctt gcatgggtaa cagaccttgt aaaccttaaa
    18841 ggtactgatg ctagtcaata tcaacacttg ttagatacag tacatccagc tcgtttcaaa
    18901 gttggacaaa tgatcggttc attcggtatc ttgatgggtg tgattgttgc tatctaccgt
    18961 aatgttgatg ctgacaagaa acataaatac aaaggtatga tgattgcaac agctcttgca
    19021 acattcttga caggggttac tgaaccaatc gaatacatgt tcatgttcat cgcaacacct
    19081 atgtatcttg tttactcact tgttcaaggt gctgccttcg ctatggctga cgtcgtaaac
    19141 ctacgtatgc actcattcgg ttcaatcgag ttcttgactc gtacacctat tgcaatcagt
    19201 gctggtattg gtatggatat cgttaacttc gtttgggtaa ctgttctctt tgctgtaatc
    19261 atgtacttta tcgcaaactt catgattcaa aaattcaact acgcaactcc agggcgcaac
    19321 ggaaactacg aaactgctga aggttcagaa gaaaccagca gcgaagtgaa agttgcagca
    19381 ggctctcaag ctgtaaacat tatcaacctt cttggtggac gtgtaaacat cgttgatgtt
    19441 gatgcatgta tgactcgtct tcgtgtaact gttaaagatg cagataaagt aggaaatgca
    19501 gagcaatgga aagcagaagg agctatgggt cttgtgatga aaggacaagg ggttcaagct
    19561 atctacggtc caaaagctga cattttgaaa tctgatatcc aagatatcct tgattcaggt
    19621 gaaatcattc ctgaaactct tccaagccaa atgactgaag cacaacaaaa cactgttcac
    19681 ttcaaagatc ttactgagga agtttactca gtagcagacg gtcaagttgt tgctttggaa
    19741 caagtaaagg atccagtatt tgctcaaaaa atgatgggtg atggatttgc agtagaacct
    19801 gcaaatggaa acattgtatc tccagtttca ggtactgtgt caagcatctt cccaacaaaa
    19861 catgcttttg gtattgtgac ggaagcaggt cttgaagtat tggttcacat tggtttggac
    19921 acagtaagtc ttgaaggtaa accatttaca gttcatgttg ctgaaggaca aaaagttgca
    19981 gcaggagatc tccttgtcac agctgacttg gatgctatcc gtgcagcagg acgtgaaact
    20041 tcaacagtag ttgtcttcac aaatggtgat gcaattaaat cagttaagtt agaaaaaaca
    20101 ggttctcttg cagctaaaac agcagttgct aaagtagaat tgtaatatac ttgaggttgg
    20161 aagctgtatt ccaacctctt attttgggag aaaagaatga aatttttaac actcaatact
    20221 cacagttgga tggagaaaga agcagaggaa aaattccaga ttttgcttga agatattctt
    20281 gaaaaggact atgatttgat ttgttttcaa gaaatcaatc aggagatgac ctcgtcagag
    20341 gtggaggtta atgaccttta tcaagctttg ccagcagctg agcctattca ccaagaccat
    20401 tatgttagac tcttggttga aaagttgtct gagcaaggga aaaattacta ctggacctgg
    20461 gcctataacc atatcggcta taaccgctac cacgaaggtg tggctatctt gtctaaaaca
    20521 cctattgaag ccagagaaat tttggtttca gatgtggatg atccaacaga ctatcatact
    20581 cgccgtgttg ccctagctga aactgtagtc gatggcaagg agctagcagt tgccagtgtt
    20641 catctctctt ggtgggataa aggtttccaa gaagaatggg cacgatttga ggctgtcttg
    20701 aaaaaattga acaagccact tttactagct ggagatttca acaatccggc tggacaggaa
    20761 ggttaccaag ctattttagc tagtccatta ggcttacaag acgcatttga agttgctcaa
    20821 gagaaaagtg gtagctatac tgttccgcct gaaattgatg gctggaaagg gaacactgaa
    20881 ccccttcgaa tcgattatgt ctttactacc aaagagttag cggtggaaaa tttacatgtc
    20941 gtatttgatg gtaacaagag tccacaagtg agtgatcact atggcttgaa tgctatgtta
    21001 aactggaaat aataactgaa aagaggttgg aactataaaa ttccagcctt ttcttactag
    21061 agaagctact ggaaatagcc taaataagtg agactactgt aatggaataa aatatggtat
    21121 aattgataag atagatagaa tcgaggatgt tatgtcattt acgaaatttc aatttaaaaa
    21181 ctatattaga gaagccttgg aggagttaaa atttacaact ccaacagagg tgcaagacaa
    21241 gttgattcct attgttttgg caggtcgtga cctagtagga gaatcaaaaa caggttcagg
    21301 taagactcat actttcttgt taccgatttt ccagcaatta gatgaagcta gcgatagtgt
    21361 acaagcagtg attactgcac cgagtcgtga gttggctact caaatttacc aagtagcgcg
    21421 tcagatttca gctcactcag atgtcgaagt tcgtgtggtt aattatgtgg gtggtacgga
    21481 taaggctcgc cagattgaga aattggcaag caatcagcct catattgtta ttggaacacc
    21541 aggccgtatc tacgacttgg ttaaatctgg tgatttagct attcataaag ccaagacatt
    21601 tgttgttgat gaagcagata tgaccttgga tatgggattc ttggaaactg ttgataagat
    21661 tgctggcagt cttccaaaag acttgcaatt catggtcttc tcagcgacta tcccacaaaa
    21721 actgcaacca ttcttgaaaa aatacttatc caatcctgtt atggagaaaa ttaagaccaa
    21781 aacggttatt tctgacacca ttgataattg gttgatttcg accaagggac atgataagaa
    21841 tgctcaaatt taccagttga ctcagttgat gcagccgtat ttggcaatga tttttgttaa
    21901 cactaaaacg cgtgctgatg aattgcattc atatctgact gctcaaggct tgaaggttgc
    21961 aaaaatccat ggagatattg cccctcgtga acgcaagcga atcatgaatc aggtgcaaaa
    22021 tctggatttt gagtatattg tcgcaacaga tttggcagcg cgtgggattg acattgaagg
    22081 tgtcagccat gtcatcaatg atgccattcc gcaagactta tctttttttg ttcatcgtgt
    22141 tggtcgtact ggacgaaatg gcctatcagg tacagctatt accctttatc agccaagtga
    22201 tgactcggat atccgtgagt tggagaaatt gggaatcaag tttagtccta agatggtcaa
    22261 agacggggaa tttcaagata cctatgaccg tgatcgtcgt gccaaccgtg agaaaaaaca
    22321 agataaactt gatatcgaaa tgattggttt ggttaaaaag aaaaagaaaa aagtcaaacc
    22381 gggttataag aagaaaattc aatgggcggt tgatgaaaag cgccgtaaaa ccaagcgtgc
    22441 tgaaaatcgc gctcgcggtc gtgcagatcg taaagctaaa cgccaaacat tttaatagaa
    22501 attgttggag tactgagctc caactttttt atttatgaga acgaactatc taaaccgaaa
    22561 cactacatta aagactgcaa attgcgatta aaaatggtat aatgataaag ttatatagtc
    22621 ccgataagat ggtaggtatt tattacgaag agttttccta tcagtacttt gtaactctat
    22681 aacaatattt tttaaggggg gacattttta tgtcagaacg taaattattc acgtctgaat
    22741 ctgtatctga ggggcatccg gataagattg cagaccaaat ttcagatgcg attttggatg
    22801 ctattttagc aaaggatcca gaggcgcatg ttgctgctga aacagctgta tatactggtt
    22861 ctgtccacgt ttttggtgaa atttctacaa atgcctatgt ggatattaac cgtgtggttc
    22921 gtgataccat tgcagagatt ggttatacca atacagaata tggattttct gctgagacgg
    22981 tgggagtaca cccatctttg gtggaacaat ctcctgacat cgctcaaggt gttaacgaag
    23041 ccttggaggt tcgtggaaat gctgatcaag atccactgga cttgattgga gcaggtgacc
    23101 aagggctcat gtttggattt gcagtagatg aaacagaaga gcttatgcca ttgccaattg
    23161 cactcagtca taaattggtt cgtcgtctgg cagaacttcg taagtctgga gaaattagct
    23221 atctccgtcc agatgcaaaa tcacaagtta cagttgagta cgatgaaaat gaccgtccgg
    23281 tacgtgtaga tacagtcgtt atttctactc agcatgatcc agaggccact aatgaacaaa
    23341 tccatcaaga tgtgattgac aaggtcatca aagaagttat tccatcttct tatcttgatg
    23401 ataagacaaa attctttatc aatccgacag gtcgttttgt aatcggtggt cctcaagggg
    23461 actcaggttt gactggtcgt aagattattg tagatactta tggtggctac tctcgtcatg
    23521 gtggtggtgc cttctctggt aaagatgcga ctaaggtgga tcgttcagcc tcttatgcgg
    23581 ctcgctatat tgccaagaat atcgttgcag caggccttgc taagaaggca gaagtgcagt
    23641 tggcctatgc tatcggtgtt gcgcaacctg tttctgttcg tatcgatact ttcggtacag
    23701 gaacagtagc tgaaagtcaa cttgaaaaag cggctcgtca aatctttgac cttcgccctg
    23761 cagggattat ccaaatgctg gacctcaagc gtccaattta ccgtcaaaca tcggcttacg
    23821 gtcacatggg acgtacagat attgatcttc catgggaacg tttggataag gtagatgctt
    23881 tgaaagaagc agtaaaataa gattttaaga ggggaacgtc ctctcttttt tatagttttt
    23941 aactatactg ggatactgtt ctgaaaatcc attttgcgaa agtagagatt tacatgtata
    24001 gtagattgaa actagaatag tacacctcaa cttctaaaac attgttagca atcaatttga
    24061 ctgtcctgat cgatttctcc tgttcttgtt tcattttact atatttcttt aaaaatgata
    24121 aaggttaaga tttctcctcg taatagataa tcttgaggat atttcaatcc aaagttttat
    24181 tcgttatcac ttgactattg caaggttttc tagagcaaca gagtcatgga atggactcat
    24241 ggttgagatt tctccttgtt gcttggactt cattcaaaag tctgttaccc aagccttgtt
    24301 caaacttcta atacactagc tgtttccata gcatgacttc tgtactagac tttcttttcc
    24361 aaataaatag atagaaccac agaatctagt aaacctagaa ttaaaattat ggtataatat
    24421 tagcaataaa agaaatctgg aggattagaa tcatggtatc aacgaaaaca caaattgctg
    24481 gttttgagtt tgacaattgc ttgatgaatg cagcaggtgt ggcttgtatg acgatagagg
    24541 agttagaaga ggtcaaaaac tcagcggcag gaacctttgt tactaagaca gcgaccttgg
    24601 acttccgtca ggggaatcct gagccacgct accaagatgt tccacttggt tccatcaact
    24661 ctatgggctt gccaaataat ggcttagact attatttgga ttatctttta gatttgcagg
    24721 aaaaagagtc gaaccgaact ttcttcttat ctctggtcgg catgtctcca gaggaaaccc
    24781 atactatttt gaaaaaagtc caagagagtg attttcgtgg tctgactgag ctaaatcttt
    24841 cctgtccaaa tgttccaggt aaacctcaga ttgcctatga ttttgagaca acagaccgga
    24901 ttttggcaga agtgtttgct tacttcacca aacctcttgg aattaaattg ccaccttatt
    24961 ttgatattgt tcactttgat caagcggcag ctattttcaa caaatatccg ctcaagtttg
    25021 tcaactgcgt taactctatc ggaaacggcc tctatataga agacgaatct gtcgttattc
    25081 ggcctaagaa tggttttggt ggaattggtg gagaatacat caaaccgact gctttagcca
    25141 atgttcacgc cttttatcaa cgtttaaatc ctcaaatcca aattatcgga acaggtggcg
    25201 ttctgactgg tcgagatgcc tttgaacaca tcctctgtgg agcaagtatg gtgcaggtgg
    25261 gaacgaccct tcacaaagaa ggcgtcagtg cttttgaccg cattaccaat gaactgaaag
    25321 caatcatggt ggaaaaaggc tacgagagct tagaagattt ccgtgggaaa ttgcgctata
    25381 ttgactaaat taaatcgaaa aatctgaaga aaggagagac gatgctagcc attgaagaaa
    25441 gtcagaagtt gactttatca aatttaccga gcctgagcct atttacaggg acagatcagg
    25501 gtcagtttga agtgatgaag agtcaagtgt tgaaacagat tgggtatgat tctgctgacc
    25561 tcaactttgc ctactttgat atgaaagaag tagtttacaa ggatgtggaa ctggagttgg
    25621 tcagccttcc tttctttgcg gatgagaaaa tcgtgatatt agattatttt atggatatca
    25681 cgactgctaa gaaacgcttt ttgacagatg atgagcttaa gtcatttgag gaataccttg
    25741 acaatccttc tccaacaacc aagttgataa tctttgcaga aggaaagctg gatagcaaaa
    25801 gacggttagt caaattactt aagcgtgatg ccaaggcctt cgatgcagta gaagtaaaag
    25861 aacaagaatt gcgccagtac ttccaaaagt ggagtcagaa acaaggtctg cagtttacca
    25921 atcattcttt tgaaaatctc ctcatcaagt cggggtttca atttagcgaa atccagaaaa
    25981 atcttctctt tttacagtcc tataaggcgg attctgttat cgaggaagag gatattgtta
    26041 acgcaattcc caagaccttg caggacaata tttttgattt aactcagttt attctgacta
    26101 aaaagatgga tcaggcgcgc gatttggtga gagacttgac cttgcaaggg gaagatgaaa
    26161 tcaaactgat tgcagtcatg ctgggacaat ttcggacttt tactcaggtg aagattttgg
    26221 cggagtctgg ccaaacagaa tcgcagattg caagtagttt aggtagttat ctgggacgta
    26281 acccaaatcc ttatcaaatc aagtttgcat taagagattc gagaggactt tctttgagct
    26341 ttctgaagca agctatttcc tatttgattg agacagacta tcagattaag acaggtcttt
    26401 atgaaaaagg tttccttttt gaaaaggcac tcttacagat tgctagtcag gtcaattgac
    26461 atttgttgaa actacaaccc gcgtcaggat tatcttgtcg tgggtttctt gctgatttgc
    26521 ttattttatt agaaagtatg tcagtgattt ccttatctat aagcaaaaaa cttgaaaaaa
    26581 gtgaatgttt gcgttatcat tttcatatag aaagaaaaag aggtattaca gatggctatt
    26641 atcttaccag aacttccata tgcatacgac gctttggaac catacatcga tgcggaaaca
    26701 atgcatttgc accatgacaa acaccatcaa acttatgtca acaatgccaa tgcagcttta
    26761 gaaaaacacc ctgaaatcgg tgaagacctt gaagccttgc ttgctgatgt agaatctatc
    26821 ccagctgata tccgtcaagc acttatcaac aatggtggcg gacacttgaa ccacgctctt
    26881 ttctgggaat tgatgactcc cgagaaaaca gctccttcag cagaactggc agcagcaatc
    26941 gatgcaacat ttggttcatt tgaagaattc caagcagcct tcactgcagc agcaacaact
    27001 cgttttggtt caggttgggc atggttggtt gtcaacaaag aagggaaact tgaagtgact
    27061 tcaacagcaa accaaaacac accaatctca gaaggtaaaa aaccaatctt gggcttggac
    27121 gtttgggaac atgcttacta cgtgaaatac cgcaacgtgc gtcctgacta tatcaaagct
    27181 ttcttttcag taatcaactg gaataaagta gatgaattgt acgcagctgc taaataatga
    27241 tagttggagg gaagaattgt tcttctcttt ttaggttata agattctggt ctgacaaaat
    27301 cgtcagactt ttttcatttt tatgagaaac gtgctaactg ctagaaatta tggtagaata
    27361 aagtattaag taatcgtgga aaaaggatat ctatgcgaaa agaaattgca cctgaattat
    27421 acaactataa caagtttcct ggtccggagt tccatttaca cggggacaag gtcgaaacgg
    27481 aagggatagc tttttccttg gttgaaaata tcaaggatgc ctttgatgtg acgactttta
    27541 atcagcgttt ttcagaagtc ttaaccaagt ttgattatat cgtgggggac tggagcaacg
    27601 aacagcttcg cctacgaggt ttttacaagg atgaccgaac agaagaaaaa cttgaaaaaa
    27661 tcagtcgttt acaagactac cttttagagt attgtagtta tggttgtgcc tattttgtct
    27721 tagaaaatga agcccctaag cgagcatcat ttgacaagaa aatgcgtaag acggaagaag
    27781 aaacaccttc tagaaaagga aagaaaccga ctcaaactaa acgaaagtcg aatgcagata
    27841 agaaaaatag acgtcgtcag aaagaccagc attctcagaa agaggacaag ggacaacgtc
    27901 attttgtcat tcgtcagaag tgagtagaga ataaggagaa gaaatgaaac cctcaattca
    27961 tagtttggca catcaaacca tgcaggaatg ggtattggag cagggagaaa agaaattccg
    28021 tgcagatcaa atctgggaat ggctctaccg taaacgtgtg cagtcatttg aagaaatgac
    28081 caacctttcc aaggatttga ttgctaagct caatgaccag tttgtggtca atcccttgaa
    28141 acaacgtatt gtgcaagagt ctgctgatgg tacagtcaaa tatctctttg aattgcctga
    28201 cggtatgtta attgagactg tactcatgcg tcaacactat ggtttatctg tctgtgtgac
    28261 cactcaggtc ggctgtaata tcggttgtac cttctgtgcc tctggtttga ttaagaagca
    28321 acgtgacctc aataacggtg aaatcgtagc gcaaatcatg ctggttcaga aatactttgc
    28381 tgagcgtggt caggatgaac gcgtcagcca tatcgttgtc atgggaatcg gtgagccctt
    28441 tgataattac aacaatgtct tgaatttctt tcgtactatc aatgatgata aaggaatggc
    28501 tatcggtgct cgtcacatca tgatttcaac ctcaggtttg gctcataaaa ttcgtgactt
    28561 tgctgatgaa ggggttcagg tcaatcttgc cgtgtctctt cacgcaccca acaatgaact
    28621 tcgttcaagt atcatgaaaa ttaaccgtgc ctttccgatt gaaaaactct ttgctgctat
    28681 tgaatactat attgagacaa caaaccgtcg tgtaaccttt gaatatatca tgcttaatga
    28741 agtcaacgac ggtgtagaac aagccttgga attggctgaa ttgctcaaga acatcaagaa
    28801 attgtcttat gtaaacttga ttccttataa cccagttagt gagcatgacc aatatagccg
    28861 tagtcccaaa gagcgcgtgt tggctttcta tgatacgctt aagaaaaaag gggtcaactg
    28921 tgtggttcgt caagagcatg gtacagatat tgacgcagct tgtggacaat tgcgctctaa
    28981 cacaatgaaa cgtgaccgcc agaaggcagt cgcagcggta aatccttaat gatgaagaag
    29041 acttataatc atattttggt ctggggagtc attttctata gcatttgcat tgtctatttt
    29101 tgctttactc ctcaagaaca atctaccgtg ggagtgggaa ctccaggtat tcagcatctt
    29161 ggacgcctgg tttttctttt gactcctttc aattctctct ggaaactggg cgaagtgagt
    29221 gacattggac aattatgttg gattttttta caaaatgtcc tcaatgtctt cttatttttt
    29281 cctctgattt tccaactcct ttatctattt ccaaatttgc ggaaaacaaa aaaggtcctt
    29341 ctttttagtt ttcttgtgag tcttggaatc gagtgtacgc aattaatctt ggactttttc
    29401 tttgatttca atcgcgtctt tgagattgat gatttgtgga ccaatacttt gggtggctat
    29461 ctggcttggc tcctttataa acgattacat aaaaacaaga taaggaatta aaatgagtat
    29521 tttagaagtt aaaaatctga gtcacggttt tggtgaccgt gcaatttttg aagatgtgtc
    29581 cttccgtctc ctcaagggag aacatatcgg cctggtcggt gccaatggtg aaggaaaatc
    29641 aacctttatg agtatcgtga ctggtaaaat gctgccagat gaaggaaagg ttgagtggtc
    29701 caaatatgtg acggctggtt acttggatca gcactctgtc cttgctgaaa gacagtcggt
    29761 gcgtgatgtt ctccgtacgg cttttgatga gcttttcaaa gctgaagctc gtatcaatga
    29821 cctctatatg aaaatggctg aagacggcgc ggatgttgat gctctcatgg aagaagtagg
    29881 agaacttcaa gaccgtctgg agagtcgtga tttctatacc ttggatgcta agattgacga
    29941 agtagcgcgt gctcttggtg ttatggactt tggcatggat acggatgtaa cttctttgtc
    30001 aggtgggcaa agaaccaagg tgcttttggc aaaacttctc cttgaaaagc ctgatatttt
    30061 gctgttggac gagccgacca actacttgga tgctgagcat attgattggc tcaagcgcta
    30121 tctccaaaac tatgagaatg cctttgttct catttcgcac gatattccat tcctcaatga
    30181 cgttatcaat attgtctatc atgtggaaaa tcaacagctg acgcgttact ctggtgacta
    30241 ctaccagttc caagaagttt atgctatgaa gaaatctcag ctagaggcag cctacgaacg
    30301 ccagcagaaa gagattgcag acctcaagga ctttgtggct cgtaataaag cccgtgttgc
    30361 aactcgtaat atggctatgt ctcgtcaaaa gaaattggat aagatggata ttatcgaact
    30421 ccaaagtgag aaaccaaaac catcctttga tttcaaacca gctcgtacac cagggcgctt
    30481 tatcttccaa gccaagaact tgcaaattgg ttacgaccgt cctcttacta agcctttaaa
    30541 tcttaccttc gaacgcaatc aaaaggttgc gattattggt gctaatggta ttggaaaaac
    30601 aactctcttg aagagtctct tgggcattat ctcgccaatc gctggggaag tggagcgtgg
    30661 agattattta gaacttggtt attttgagca ggaagtagaa ggcggtaatc gccaaactcc
    30721 tcttgaagct gtctggaatg cctttcctgc ccttaatcaa gcagaagtcc gtgcagccct
    30781 tgcccgttgt ggtttgacaa ccaaacatat tgaaagccag attcaagtat tatcaggggg
    30841 agagcaagcc aaggttcgtt tctgtctctt gatgaatcgt gaaaacaacg ttttagtgct
    30901 ggacgagccg accaaccatt tggatgtgga tgcaaaggat gagctcaaac gcgctctcaa
    30961 agaatatagg ggatctatcc ttatggtctg ccacgagcca gacttttatg aaggctggat
    31021 agaccaaata tgggatttta ataatttaac ttaagaatga gagtaaaaga aatacagtac
    31081 cgaatgtgga tactgtattt ttttggtttt taagatttaa aatcgtagtc tttcaccact
    31141 tcgatgctgt cgattgtgat agcagtagtt ggcttgtctt tttcatcttt ttcggcctta
    31201 gcaatcttat ccacaacatc cataccgtca atcacttgac caaagactgg gtgtttgcca
    31261 tctagactag ggtttccacc ttctttgtag gcttcgataa ttttctgtgg atacttgctt
    31321 gtagggagtt tagaagaggt atctgtagag ttttggttga tgaagaactg gctgccattg
    31381 gtgtttggtt gaccagtatt agccatagca agagcaccgc ggatgttata caaataagga
    31441 gtaatctcgt tcttgaaacc agttcctttg tctttagtct tatccttgtc atgccagatg
    31501 gactgaccac ctgtaccgtc cccttttgga tctccagttt ggaccataaa gccatcgatg
    31561 acacggtgga aggtaatacc gttatagtag ccttctttgg cgtgagtgag gaaattttca
    31621 accgctagag gagcgagttt agggaagagt ttaatgcgaa tatcaccttg gcttgtgtgg
    31681 agaatcactt cggcttcatc ttcagcaact tccttagata gttgtgggaa attggcgttt
    31741 tcgtttgtta aagcatcgtt taactccttg gcagattggg cagctacttt ggaactttct
    31801 tcagcagcaa gactggaatc aacataatca tcaccacgca gactgcgttg gacgctgcta
    31861 cacccagcta gggctacagt agacagtaaa agaagggttg ctagtttttt cattctgatc
    31921 ctctcaaaaa ttcatttata ccattgtacc ctaaaaggaa gtggatttca aatattagta
    31981 gtttacagaa ctggcttaga taatagttgg gatttcatca tcatcttgaa aatcttcaac
    32041 ttcttcccca gtaaatggtt tctgaaaaga acttagtata aaacgggcaa ttggttcaac
    32101 aattaggaaa tttagaggaa gagctgcaat aaagtttacg aaccaggcgc ttagataggt
    32161 attgggtgtg atagcaatgc cattgtaaaa aagtccatag aaggacatga aagtgaccag
    32221 ctaattcttc ttctgaaaaa tgctcatgaa gggcttgatc caggtcgcaa gatttcattt
    32281 tagaaagtcc agtaactccc ttcttcttca ggatattctt tttcatggta ttatttagat
    32341 ggtcaagtga gtcaaaagaa gtttcgacaa gagcataccc tttttctacc agagttttta
    32401 gatgtttagg ggcatcaata ccataagtgt actcaaagta ttttggaaac cagatcttaa
    32461 gaaagctcgt aaagctagcc agttctctaa acgctaagaa ctagctacaa cacagcattt
    32521 acaacacttc atggttcaca ccatggggtg ttttttaatg attttaagca aaattcacac
    32581 ttaattgaaa gttatttaaa ttagatgaaa atttattttt tgaaaaagtg ggaaaacatt
    32641 gattctaagc gaattttgaa tcatattcga atgggagttt ttaaaatcat gtttcagtgg
    32701 taaaagtacc aaactggatt ctccatagta aaatgatatc tcctgctagt gaatcatcta
    32761 ctaataagtc catatttcgc ttgggaacgg gcttgggact tagaagccaa gtatccaact
    32821 ctcgttcagg cgatatgaag ggtttgactt ggtgttcttt at
//
LOCUS       DAVHSI010000020        32518 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.020, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000020 DAVHSI010000000
VERSION     DAVHSI010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.020"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(216..1778)
                     /gene="guaA"
                     /locus_tag="VVR21_001145"
     CDS             complement(216..1778)
                     /gene="guaA"
                     /locus_tag="VVR21_001145"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU6055039.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            1920..2618
                     /locus_tag="VVR21_001146"
     CDS             1920..2618
                     /locus_tag="VVR21_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6055040.1"
                     /translation="MLPAYMKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2661..3557)
                     /locus_tag="VVR21_001147"
     CDS             complement(2661..3557)
                     /locus_tag="VVR21_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU6055041.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMILTYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(3566..4501)
                     /locus_tag="VVR21_001148"
     CDS             complement(3566..4501)
                     /locus_tag="VVR21_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU6055042.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4498..5223)
                     /locus_tag="VVR21_001149"
     CDS             complement(4498..5223)
                     /locus_tag="VVR21_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU6055043.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(5307..5942)
                     /locus_tag="VVR21_001150"
     CDS             complement(5307..5942)
                     /locus_tag="VVR21_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU6055044.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(5944..6771)
                     /locus_tag="VVR21_001151"
     CDS             complement(5944..6771)
                     /locus_tag="VVR21_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6055045.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGLKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6793..7129)
                     /locus_tag="VVR21_001152"
                     /pseudo
     CDS             complement(6793..7129)
                     /locus_tag="VVR21_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(7130..7858)
                     /locus_tag="VVR21_001153"
                     /pseudo
     CDS             complement(7130..7858)
                     /locus_tag="VVR21_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8371..8982
                     /locus_tag="VVR21_001154"
     CDS             8371..8982
                     /locus_tag="VVR21_001154"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU6055046.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9027..9755
                     /gene="rlmB"
                     /locus_tag="VVR21_001155"
     CDS             9027..9755
                     /gene="rlmB"
                     /locus_tag="VVR21_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU6055047.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9794..10705)
                     /gene="trxB"
                     /locus_tag="VVR21_001156"
     CDS             complement(9794..10705)
                     /gene="trxB"
                     /locus_tag="VVR21_001156"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU6055048.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10771..10995)
                     /locus_tag="VVR21_001157"
     CDS             complement(10771..10995)
                     /locus_tag="VVR21_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU6055049.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11073..11816)
                     /locus_tag="VVR21_001158"
     CDS             complement(11073..11816)
                     /locus_tag="VVR21_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6055050.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11816..12616)
                     /locus_tag="VVR21_001159"
     CDS             complement(11816..12616)
                     /locus_tag="VVR21_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6055051.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12774..13130)
                     /locus_tag="VVR21_001160"
     CDS             complement(12774..13130)
                     /locus_tag="VVR21_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU6055052.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13124..13654)
                     /locus_tag="VVR21_001161"
     CDS             complement(13124..13654)
                     /locus_tag="VVR21_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU6055053.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(13654..14148)
                     /locus_tag="VVR21_001162"
     CDS             complement(13654..14148)
                     /locus_tag="VVR21_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055054.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14283..14729
                     /locus_tag="VVR21_001163"
     CDS             14283..14729
                     /locus_tag="VVR21_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU6055055.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14726..15373
                     /locus_tag="VVR21_001164"
     CDS             14726..15373
                     /locus_tag="VVR21_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU6055056.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLVIIPAII
                     NQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(15394..15975)
                     /gene="pdxT"
                     /locus_tag="VVR21_001165"
     CDS             complement(15394..15975)
                     /gene="pdxT"
                     /locus_tag="VVR21_001165"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU6055057.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(15976..16851)
                     /gene="pdxS"
                     /locus_tag="VVR21_001166"
     CDS             complement(15976..16851)
                     /gene="pdxS"
                     /locus_tag="VVR21_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU6055058.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17003..18382)
                     /locus_tag="VVR21_001167"
     CDS             complement(17003..18382)
                     /locus_tag="VVR21_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU6055059.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            18676..19599
                     /locus_tag="VVR21_001168"
     CDS             18676..19599
                     /locus_tag="VVR21_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU6055060.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19659..20264
                     /locus_tag="VVR21_001169"
     CDS             19659..20264
                     /locus_tag="VVR21_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6055061.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAKIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20283..21527
                     /locus_tag="VVR21_001170"
     CDS             20283..21527
                     /locus_tag="VVR21_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU6055062.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLMGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(21644..21901)
                     /locus_tag="VVR21_001171"
     CDS             complement(21644..21901)
                     /locus_tag="VVR21_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU6055063.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(21943..23979)
                     /locus_tag="VVR21_001172"
     CDS             complement(21943..23979)
                     /locus_tag="VVR21_001172"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU6055064.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHDVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKADLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24239..25156)
                     /gene="glyQ"
                     /locus_tag="VVR21_001173"
     CDS             complement(24239..25156)
                     /gene="glyQ"
                     /locus_tag="VVR21_001173"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU6055065.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(25524..26285)
                     /locus_tag="VVR21_001174"
     CDS             complement(25524..26285)
                     /locus_tag="VVR21_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6055066.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26558..27400)
                     /locus_tag="VVR21_001175"
     CDS             complement(26558..27400)
                     /locus_tag="VVR21_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU6055067.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(27514..28905)
                     /locus_tag="VVR21_001176"
     CDS             complement(27514..28905)
                     /locus_tag="VVR21_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU6055068.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29140..29517)
                     /locus_tag="VVR21_001177"
     CDS             complement(29140..29517)
                     /locus_tag="VVR21_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU6055069.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            29750..30727
                     /locus_tag="VVR21_001178"
     CDS             29750..30727
                     /locus_tag="VVR21_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU6055070.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSEEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGLLFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            30724..31806
                     /locus_tag="VVR21_001179"
     CDS             30724..31806
                     /locus_tag="VVR21_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6055071.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(31870..32518)
                     /locus_tag="VVR21_001180"
                     /pseudo
     CDS             complement(31870..32518)
                     /locus_tag="VVR21_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         9625 a         7298 c         5836 g         9759 t
ORIGIN      
        1 tattagaaag ttggctctct aattaaatta attctcatta tatatatcaa aagaccgcag
       61 cttgaaaact acggtctaat tttttgtcca aatgtaaacc acttggaact attattcaat
      121 ttattctttt tagtaaatgt tcccgtttta atcccagtta cagtttttaa tcctctgtaa
      181 ccgttgattt tacaaagctt ttaatttttt tgcgattatt cccactcaac tgttgcaggt
      241 ggtttacttg taatatcgta gacgatacgg ttaacatgat ccacttcatt tacgatacgt
      301 actgagattt tttgaagtac ttcccatgga attttggcaa aatcagcagt cataccatcg
      361 atagaagtga tagcacggat tgcaatcgtg tagtcatacg tacgaccgtc acccataaca
      421 ccgactgaac gaacgcctgt gttaacagtg aagtattgcc aaatatcgcg gtcaagtcca
      481 gctttagcga tttcttcacg aagaatagcg tctgattcac gaacggtttc aagtttctct
      541 tcagtgattt cacccatgac acggatagca agtcctggtc ctgggaatgg ttggcgccat
      601 acgatatggt ctggcatacc aagctctgta ccaagagcac gaacttcatc cttgtaaaga
      661 gtattgagtg gttcaatcaa ttcaaactgc atatcttctg gaagaccacc cacgttgtgg
      721 tgtgacttga tagtttgagc tgtatccgta ccagactcga taacatctgt atataaagta
      781 ccttgagcaa ggaatttcac atctttgagc ttgcttgctt cgtcatcgaa tacatagaca
      841 aactcgttac cgatgatttt acgtttttgt tcagggtcag aaacgccagc aagtttgtca
      901 aggaaacgtt tagcagcgtc tgctttgacg atattcaaac caaacttacc accgagcatg
      961 tccataactt gatcagcttc gcctttacga agaagaccgt ggtctacgaa gatacagatc
     1021 aattgatcgc caatcgcttt ttggagaaga accccaacga cagatgagtc aacaccacct
     1081 gatagaccaa gaaggacacg tttatcaccg acggtttcac gaattttttt gatctgcatg
     1141 tcaatgaaat tatccattga ccagtcacct ttagccttac aaatgttaag ggcaaagtta
     1201 cgaaggatat catttccgta tacagaatga cgaacttctg ggtggaattg gataccgtaa
     1261 atgtgtttat ctgggttttc gatggctgcg tatgggcagt cagctgatgt acctgtacga
     1321 acaaagtcag caggaatctc agtaaccgca tcaccatggc tcatcaaaac agtctgttca
     1381 tcaggtgttg attcaaaaag cgctgatggt gtgtgtgtta gggttgattg accgtattca
     1441 cgatttccag catcacctgc aggaacaact tttcctccaa gtttatgggt caataactgc
     1501 ataccataac agattcccaa aattggaatt ccgagttcga agatttctgg gtcaatatca
     1561 aatgaaccat cttcatatac agaatttgga ccacctgata gaataattcc tacaggattg
     1621 acttcacgaa cttcagcagc tgaaatttta tggcttttta gttctgaaaa aacaccaatc
     1681 tcacggatac ggcgtgaaat cagctggttg tactggctac catagtccaa tacgatgatt
     1741 ttttctacat cttgcaaatc agttgaaatg ttgctcatct ttttcctttc tcaaaagaaa
     1801 tatcttttcc caatattcta tcacaaataa gggcgaatta ccaactaaac aaggcgaagt
     1861 ttgacttttt ctagtttatt gaggtacaat agagaaaaga tagaaatgaa gtgaaaaata
     1921 tgctacctgc ttatatgaaa atccatgatc agataaaaaa ggatattgac gagtaccgtt
     1981 gggctattgg tgagaggctt cccagtgaaa gagatctagc tgagcagttt gcggtcagtc
     2041 gcatgaccct ccgccaagcc gtatctctat tagtcgaaga aggcgtctta gagcgccgtg
     2101 taggaagcgg cacctttgtt tccagtactc gagtacaaga aaagatgcga gggacaacca
     2161 gttttactga aattgtcaaa tcccaaggta aagttccctc tagccagctc atttcctaca
     2221 aaaaaaccat tcccaatgag caagaagttg ccaagctagg aatttttcca acggacaata
     2281 ttatccgaat ggagcgggtc cgctatgccg accaagttcc cctagtttat gaagttgctt
     2341 ctattcctga aaaattcatt aaggacttta aaaaagaaga aatcaccagt catttcttcc
     2401 aaaccttgca aaaacatggc tatcgtatcg gcaaatctca acagaccatc tatgctcgcc
     2461 ttgctaaaga aaagattgcc cactatttgg aagttgaaaa aggacatgct attcttggat
     2521 tgacccaggt ttcctaccta gaagatggta ctgcttttga atacgtaaaa agtcaatatg
     2581 taggcgaacg ctttgaattt tatcttgaaa ataattagat taccacgcaa aaactctctg
     2641 tcacggacaa agagtctttt ttatttttct aagaataaat ctttcaaaga aatcaaagtt
     2701 acagcaaaca atatcattgc cataccaata aaatcaatgg gataaaattg ttcattcatt
     2761 attaagaagg caaagaaaac cgccgatatt ggctcaattg aagccaacaa gcttgacttg
     2821 accggtccta tcagactggc tcctttaagg aaagctgtat aggcaaagac agtcccgata
     2881 aggataatgc ctgcaaacgc aaggagaaaa tcaagactag tcgggatatc ggcctgtaga
     2941 acccctgtaa aaggaagggc gaccaaacct gctatgacca ttcccacacc aatgaccaag
     3001 ctgctccccc actttttaat caaggctatg ggtaaaatga tatacagagc ataagtcaag
     3061 gcagaaaaga gaccccagaa caggccagca ggtgtcatgg ataactggtc caactgccca
     3121 tgtgttgcga tcaggaaggt tcctccgatg gcgaatatga tggaaactat ctctcccagt
     3181 gtcggtgcca ccctatcctt gatacagcta taaattaaaa ttccgacagg acaaacatac
     3241 tgaagcaccg tcgctgttcc cgcattggtc tcctgaatag cagacagata ggcgaattgg
     3301 ttgagaaaaa gaccaatcag agcaaaaata agaagagaca gcaaactctt tctatccttt
     3361 aaaaagacca gtattttatc ctttgcagta gcataagtca agatcatgag aattccacca
     3421 gcgattaaaa gacgcaagtt ggtcaagacc agagccgaaa ttccgtgtgc cattaggtat
     3481 tggccactcg ttcctgacaa cccccaagca ataccagcca caactgttag taaagtccct
     3541 tttaaactat ttgacatgtc tctccttact cttctttacg aatcaagttc atcacttgat
     3601 tgcggtctaa tatccattga gctctctcgt ccttttcata ggtacgattc gataggaaaa
     3661 tagtggcttc ttgcttctga cgattccaca tgataaaggt acctgtatag cccgtatggt
     3721 ctagccaatc tccttccaaa ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa
     3781 aattttgatt taagtctctt gcaaaatcat ctgctaaata gtgttctaaa aagatttgta
     3841 aatcctttat agtcgaaaat aaaccagcac tcccagcatg tctacccagg agacgagcct
     3901 tgggatcatg cactatgcct gcctctacac ctctaactgt tggaacagca agctcaactg
     3961 gcccaaactt ggtttccgtc attccccaag gtttccagac ttgatccttt aaaatcacat
     4021 ccaaatcttg attaaaaatt ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg
     4081 aataaagaaa ggctggctga cttcgtctgt tgagatgaaa catcgcttcc tttaattcag
     4141 gggctgttaa aagatcacga ttaggaataa aaggatcaag gtctgttgca tgagtcaaga
     4201 gctggcgaat agtgatgtct ggataatcac tctcaggtaa aaaatctatt accagtctat
     4261 caatatctaa ttgacctatt tcccacaaga aggtacaaac tgtgccaacc ccaacaacct
     4321 tgctgacact agctaggtca taaactagtc ctgcctcagt ctgcaagcca tgctctgggt
     4381 cactctggcc taaatagaac tctgtccatt gattgtcctt aaaatacgca aaagaggctc
     4441 cgggataaat tcctgcctcg atttgttctt ctattttttt aataatcttg gtccacttca
     4501 tacttcttca aaccacaatt caacattatt tctatcttta caaaggaaga atttttcaga
     4561 cttaggaata aaatattcag tagactcaaa cttctggcga agacttgcta tgtctaattc
     4621 attgaccaag aacttgagca tagataagtc ccaggtaacc gtattgtcca cagtcaaatc
     4681 ctgcccctga gctggaataa aatcaaggga tgccccaatt tcagatgatt ccaagaaact
     4741 ttcgatatca gttgggagat gtaattccat agaaatctca aatttactta aagaaattga
     4801 tgccaaatct gtttgaaatt caggcttttc tcctacttct actagacttg ctctgtcatc
     4861 ttccgcatga atcaaaatca aatcatcttc tggtgagaaa atttcaaaag cgtagccatt
     4921 ttgaccttta tataatcgat gaatcgaatc tgttttagat aagattcctt caatttctaa
     4981 gggattttcc accttgacaa tcaatctagc tagttttttt cttccctcta ccttacgagt
     5041 acgcatactg ggagcttctt ctaaaaccag cttttcaaga cccgtttggt cacctagtga
     5101 cagaaaggcc gattcttcta acaaggcctt cattccaagg gtttcaatat aaaatgtttc
     5161 atttaatttt ctattattag cttttaaagt aggaataatc cgtacaatct gatttacatt
     5221 cataaattcc tccgtcactt tttattttaa aggattttag aattttttac aagatattat
     5281 gctcaaattt aacattattt agctatttag taaagatagt ctttcaaggc ttttgacaaa
     5341 gcctgataac cagcaatact gaggtgcagt ccatcagttg tatattcttt tttgagttgg
     5401 cctgcttggt ctgtcaaaca atcaaatact ggcacaaatt ccacctgcat ataggcagat
     5461 gcaagctctt gataggcttg attccagttc tgaatttttt cattcgagcg gatatagact
     5521 gcctgctggt acttctctcc ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc
     5581 aatggataat cgcgagcaac ggattgaatg atagcttcga gattattgag agcctcattc
     5641 acaggaacat cctttccgat atcatttgtc ccaatcagaa gaaaaatttt atctactgct
     5701 ccaccatata gatgagcatc aaggttctct agtaacagtc ctgtctgata gccacgaatt
     5761 cctcgattga caatcgtctt tgaagtccca aatagctcct gtagaggata atactcgaca
     5821 atggaatccc caataaaaag aatgtttggt tctacaacag aaatgtgatt taggtgacga
     5881 tatttggttt gaattttttc ttgttccttt aggagccaat tttctaataa ctgtactgcc
     5941 acttcattct cctttttcta accagttttc caagacttga taaactcctc cttggctgtt
     6001 ggctggtgct agagcagtcg ccacagcttt ggctttctca tcagcatttt ccatcgcata
     6061 ggcaattcca gccatttcaa gcatttcaac atcattttca ctatcaccaa aagccatgat
     6121 ttcttgggat ttcaagtccc agcgcttgag taattcctcc aagccccatg ctttatgaat
     6181 cccagcttgg aggatatcaa tgcaaccata gccactggat acagctcgga cacggccatc
     6241 aaagagagca ttgatttctt ccaaaaccga actcaaacgt tcctcaccaa caaccatgct
     6301 catcttgagc acaccaccaa agaggtcaga tgttaattca tccacaaatt gcatccgttg
     6361 gtagaatttt tcaatcattt ctggagtcat aaaactttca agatctgtaa aaatcgtacc
     6421 ttccttgaca aaatcaccct tcagccccgt tacaacaaac tggtcctgac acgctcgacc
     6481 cttgaaatga gccaaagcct tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa
     6541 ttcattgttt tcaaaaatac gagcgccatt agcaacaacc agaaccactc gatccaccaa
     6601 gggactcagt agttgtctca tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat
     6661 gcccctttga tccaactgat ctaaaatctt ttccaatcgt gggagatcaa gctgacccct
     6721 agcatccagc aaggtcccat ccatatctgt cgcaattacc ttaatcatca tttactttcc
     6781 tctggattca agctaatacc acttcaatcc cacatgttca ttcatttctt tataggctgt
     6841 atcaattcgt tccttagtcg cttcatctaa ctggtcacga tgactgccac ccctctataa
     6901 aatcttccaa aatataagtt tggtaatgat acaagggata tccttctggt gaaaaggttc
     6961 cctttggtgt tcgattgacc caagtaggat gagctttagc tgttccgata gttgtttttc
     7021 catccttctt cttgatggtg acatccatga gaacaccacg ttcagtccac ttagcattct
     7081 cttcatctcc catagattca attcgttgat tggaaatgaa gttccccatt taatagataa
     7141 tgagtttctt atctccatct ttttcaaccg tttcagatgg ttcaacaacg tgaggatgcc
     7201 ctccaaagat aatatccgct cccaaatcga tcatcttgtg ataaagagct ttttgttctt
     7261 cagttggttc caatcgatac tcaacaccca tctgaagcat gataatggtg atatctgctt
     7321 ccttctctgc ccgttcaatt tcaaccttca tcttatcttc gtttaaatct gaaagataac
     7381 gattatagtc ttcctgagaa atatactgct caattccatt gaaaccatag gaataggcta
     7441 acaatgcaac cttgatacca ttcacttcct taatgaccag cggagcctga tcacgtggtt
     7501 cgtgcgtata aactccgatt ggagtgattc cagctttctc aataatatcg gccgttgaaa
     7561 taactccctc aatttgcgaa tccaaaatat gattatgagc taaatccagc acatgataac
     7621 ctgcctcctt aatagcatcc ataacttcaa caggagcatt aaagagaaga taacccgcta
     7681 aataatgatc cttattaatg gttccttcaa aatcaccaat agctaaatct gctgcttagt
     7741 ccccttgctt gagccaagga gtcacatact caaaattttc atgaaagtca taggtaccgt
     7801 cttctttttt agctgaaaag aaaagtccat cgtggtagag caaatccccg tgggccataa
     7861 ttctggcagt tttttcctct tcctactcct gagacttttg cttagtcccc tcttgagaaa
     7921 tagtatctcg tttttgacta gtcaagggat tccttggaag ctttcaaaca acaagaccaa
     7981 gcccattgat aaaccaactg ctagcaagag tatcgccaca aatcccttat tgctccactt
     8041 gcgataactc ctaaaaagtt taccaagccc ttcataaaac gaaaagctaa accaccctga
     8101 tttcgatttt gtcttctttg tatcttcgtt ctccctactt tcttatgcaa gccttttctt
     8161 tttattatat cacagataag tatttctttc tcaattgaat tgaacttccc atctattttc
     8221 tataaatcct aaatgccata atgctttcaa ttcttgtcat tttgtgatat catgtagagg
     8281 aaatgaacta atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta
     8341 actgcactaa acataatata aggagagaaa atgtctgcaa tagaacgtat tacaaaagct
     8401 gctcacttaa ttgatatgaa cgatattatc cgtgaaggga atcctactct acgcacggtt
     8461 gctgaggaag tcactttccc cctatctgac caggaaatca tcctaggcga aaagatgatg
     8521 caattcctta aacattccca agatcctgtc atggctgaaa aaatgggact ccgcggtggt
     8581 gttggactgg ctgctcccca gttagatatc tcaaaacgca ttatcgctgt tttggtacct
     8641 aatattgttg aagaaggcga aactccacag gaagcctacg atttggaagc cattatgtac
     8701 aatccaaaaa tcgtctctca ctctgttcaa gatgctgctc ttggcgaagg agaaggttgc
     8761 ctgtctgttg accgtaacgt gcctggctat gttgttcgcc atgcccgcgt tactgttgac
     8821 tactttgaca aagatggaga aaaacaccgt atcaaactca aaggctacaa ctccattgtt
     8881 gttcagcatg aaattgacca cattaacggt atcatgtttt acgatcgcat caatgaaaaa
     8941 gacccatttg cagttaaaga tggtttactg attcttgaat aaagaaaatc ccgttgcaag
     9001 acggggtttt gtgttataat agaggcatga aaacaaatga tattgtctat ggtgtccacg
     9061 ccgttaccga agccctcctt gcaaatacag gaaacaaact ctacctccaa gaagatctcc
     9121 gaggtaagaa tgttgagaaa gtcaaggaac tagctacaga aaagaaggtg tccatttctt
     9181 ggacatcaaa aaaatctctc tctgagatga ctgaaggtgc tgttcatcaa ggttttgttc
     9241 tacgagtgtc tgaatttgcc tatagcgagc tagattacat ccttgcaaaa acacgccaag
     9301 aagaaaatcc acttctattg attctagatg gtctaaccga tccccataat ctgggttcta
     9361 tcttgcgaac agccgatgcg accaatgttt caggtgtcat cattcccaag caccgtactg
     9421 tcggagtaac tcctgtcgtt gccaaaacag ccacaggtgc tattgaacac gttccaattg
     9481 cccgagtgac caacctcagt caaaccttag ataaacttaa ggatgaaggt ttctggacct
     9541 ttggaacgga tatgaacggt actccttgcc acaagtggaa tacaaaaggg aaaatcgccc
     9601 tcatcattgg aaatgaagga aaaggtatct ctagcaacat caaaaaacaa gtcgatgaga
     9661 tgattaccat tccgatgaat ggacatgttc aaagccttaa tgccagtgtt gctgcggcca
     9721 ttctcatgta cgaagttttc cgaaatagac tataaaaaag tttccagtca tctgattgga
     9781 aactttttta tgattaacta tgttctgtaa tgaatttata ggcttcttga ccagcgatag
     9841 ctccatctcc aaccgctgtt gttacttggc gaaggtcttt caagcgaaca tctccaactg
     9901 caaagatacc gtcgactgca gttttcatgt ggttatctgt cacaatccat cctgcctgat
     9961 cttggatatt caattcttta acaaaatcgc taagagggtc caaaccaaca tagataaaga
    10021 caccaccgaa ggcttgttct gtcacttgac ctgttttcac attttcaaat acgactgatt
    10081 ctactcggtt ttcacccttg atttccctta ctacagaatc ccagataaag ctgatttttt
    10141 cattcgcaaa ggcgcgatct tgtaaaacct tttgggcacg aagttggtca cgacggtgaa
    10201 caatggtaac agtcttagca aaacgagtca agaagagggc ttcttcaaca gctgaatctc
    10261 caccaccaac taccaataaa tcttggtcac ggaagaaagc accatcacac acagcacagt
    10321 aagaaacacc acgactgttc agttcttctt ctccaggcac tcccaaagga cggtgtttag
    10381 aaccagttgc tacgataact gtacgtgttt catatgtttg gtcatcagtc atcactttct
    10441 taaaatcacc atggtcttcg acattttcaa cataaccata aatgtgctca acaccaagat
    10501 tttcaagtgg ttcaaacatc ttttcagcca attcaggtcc actaatatta gcgtatcctg
    10561 ggtaattttc gatatcagat gtattattca tctgaccacc tggcagacca ccttcaatca
    10621 aagctacttt tagattgctt cgagcagcat acaaggccgc agtcatccct gcaggtccag
    10681 caccgataat aatagtatcg tacatataga ttccttcttt cttgttgtaa ctatctttat
    10741 tctaactctt tcttgtcaat cacgcaagga ttatgccttg aaaacaagaa ttaaactcat
    10801 aaccgcaaag gataatactg ggacaaccaa gactccaatc ataatcatat catagagatg
    10861 ggcttggcga gccctggctg tcttatcaac tcccgacatg gctctcagac caatccaaat
    10921 ccctaaaaaa atcagaacaa ggatggtggt caagatcaaa ctctcgaaat ataaagaaaa
    10981 tagttgcagt agcatgattt ctctcatttc tatctttttt aaagagtaaa ctcagctagt
    11041 ccaactaact gagttttcct ttatctatta tatcaaatat aagtccgttt gtaactagcg
    11101 aagaattctt ttgtccgctc ttctttaggg gtgtggataa tctcatccgg agttccagac
    11161 tcgatgattt tccccttatc taagaagaga atcttatccg caacttgggc tacaaaggac
    11221 atgtcatgac tgaccaaaat catggtctga cctgacttag cagcatctgc aatagacttt
    11281 tctacttcac cgaccaattc tgggtcaagg gctgaagttg gttcgtctaa gagcaaaaca
    11341 tctggtttca tagcaagcgc acgcgctagg gcaacccgtt gcttctgtcc acctgataaa
    11401 tggcgaggat aatggttttc acggtccgaa agcccaacct tagccaactc ttccttggca
    11461 atcttagtcg cttcttggtc agataatttc ttgacaacaa ccaagccttc tttcacatta
    11521 tcaagtgctg ttcggcgttc aaataaatta aactgttgga aaaccataga caacttacgg
    11581 cgtagggcaa ggatttcttc ttgagtgatt ttagaaaaat caactgaaaa accatcaatc
    11641 tgaatagagc cactgtcagg tgtttcaaga taattgagac tgcgaagaaa ggttgatttt
    11701 ccagctcctg aagaaccaat caaggctaca acttcccctt tttgaatatc caagtccaga
    11761 tgatccaaga cagtctgtcc tgaaaaggat ttgcttaaat tcgaaatctt aatcattaac
    11821 gaaggtctcc tttcacatct gtttgcactg tatcaggtgc agaaatagcc atttttctct
    11881 cgatgaaacg accgaggctt tcaattccga tattgactac ccaataaaca agggcaacgg
    11941 agatgaagcg ttcaaaatag cgataatcag ctccacctag aatctgagct tgggcaaaga
    12001 cttccacaac acccgcacta aaagctagag atgttccctt ggtcaaaccg atgagggaat
    12061 taatcaaggt tggagtagct accaccgctg cattaggaat aatcactcgt cgataaactt
    12121 gcgctcgggt catacccaga ctgcgtgccg cctcaatctc accaggatta actgagagaa
    12181 tggctgcacg aatggtttca ctagcataag ctgcctcatt aaaggcaaag gcgacaatcg
    12241 caaaagctgc agctggaatc gcattgatat tgagaccagt tccccattgc tgattgaggg
    12301 ctttcaaagc caaagggatt ccgtagtagg tcaacatgag ttgcaccaaa atcggtgtcc
    12361 cttttaagaa actaacaaag aaggcctgca agggatataa aatcttgaca cgattgatct
    12421 tcacaatggc aaaaagaagc gccaaaacca agccaaaaag ggcaccacca attgtcaaca
    12481 taattgttgt tggaagttgt tggacaattc tagggattcc atcaaagacc gaacgtaggc
    12541 taaacagctt gccatccgga atcaattgca tcaagttttg gtaccaatct gatgctaaaa
    12601 tcgttgtaac attcataaaa acatcctctt ctgataatga ttcattctac catgcttctg
    12661 ccgtcaatga aattatttgc tacggtcaga tacagacttt gtctacctac tagtttatca
    12721 tactttgaaa cagggaagtt atatatttta tctatcaaag agatagataa aaactatttc
    12781 agtcccagtt cttcataaga ttttcgataa ccgatttgct taacggttcc attttctact
    12841 aaaatgggcc gttttaacaa cataccgtca cttgctagca actcagccgc ttcttggttt
    12901 gacaaacttc ctaccttatc ttttagccct aattcacggt atttgatacc actggtgttg
    12961 aaaaattgct tcaattcaaa tcctgaggtt tctagccaat tcaaaatgac ttcttggcta
    13021 ggtgtttctt ccacgatatg gacggcttta tagtccacac ctaattgatt taattcttgt
    13081 tttgcttttt tacaagttga acatttggga tattcgataa attctaacat gtgcttctcc
    13141 ttctattgtt tctatcttta aaatctactc cttcatgctc caagagccaa gctttctttt
    13201 ccactcctgc agcataacct gtcagacgct tgcctgctcc caacacacga tgacaaggta
    13261 ctaggataga ccaaggattg cgtcccactg ctccaccaat tgcttgagca gaagccactt
    13321 gcaggtcttg agcaatttgt ccataggtca ctgtctgacc ataaggaatg ccctgtaaat
    13381 agtcccaaac tctcttttca aaattcgttc cgattggcgc caagagcaag ttggataaat
    13441 cctgaggctt gcctttaaag taatcatcta agcaagcaat aactgggtct aaaataggat
    13501 gactaacaac ttcttctatc gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct
    13561 gaacccaaat tccatacaaa taatggtcat cagctacaag tgatagaata ccaattggtg
    13621 aggagtagag tatttttaca tacttctttt gcattatttc tttaattttt gataggccaa
    13681 gcgttcgcca tctactggca ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg
    13741 ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa tcaagataat caaaaccttc
    13801 aatcaagccc tctaagaagg tttgagcaac tccttttccc tgcacatctg ctgccacagc
    13861 aatacggtga aagactagat actctgactc tccagcttgc cagtttccct cataaatagc
    13921 ttcataggcc tcctctggac tcttggtcac agcagcatag gctagcagtt ctccctcttc
    13981 caaggctacg taggcttgcc ctgagataat atcatcgata ataacatctg catttggata
    14041 gccattttgc cactggtcac taccagcatc tgctaaacat tttttggcat cctccatcac
    14101 ctgcatgatg gcatctactt catttggaaa agctaaacga atttccatct tttttcctca
    14161 tttctgacta gtttctccca tcatagcata atttaagtat ttctacaagc agttaaaact
    14221 tgactttgtg tttttgttat tttataatct agttatcaaa actatataaa aaggagttga
    14281 aaatgaaaac taccttttcc tacccaaaat gggcagaaat tccaaacatt gacctctatc
    14341 tggaccaggt tttgctctat gtcaatcagg tctgcgcccc tatctctcct aataaagaca
    14401 agggcctaac agcatctatg gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg
    14461 acaaaaaaaa ataccaacgc caacagattg cccgtttgat tgctatcaca accctcaagt
    14521 ctgtattttc tattcaagaa atagcccaga cacttaatac tctacaaact caagcaagtt
    14581 cagaccaact ctacgatgct tttgtggact acatgaacca aggaattgac ccagctaacc
    14641 ctattatcca aaccagctgc caaaccgtta aactctatca tcaaactcta gacttaatcg
    14701 atcatactca agaggaggta atccaatgaa cactagtctt aaactcagca aacaactcag
    14761 ttttggagag gagattgcta atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat
    14821 cttgctgcct atttcatcca tctatagtta tgaagcacac ggatttttat cctctatcgg
    14881 cgtttccatt ttcgtcatca gtctctttct catgttccta tcatccacca tttatcactc
    14941 tatggcctat ggttcgaccc acaaatatgt tttgcgaatc attgaccatt ctatgattta
    15001 cgttgccatt gccggctcat acacgcccgt tgtcttgacc ttgatgaata actggtttgg
    15061 ctatctgatt attgtcatcc aatggggaac gaccatcttt ggtattctct ataaaatctt
    15121 tgctaaaaag gtcaatgaga aatttagcct tgctctttac ctgattatgg gctggttggt
    15181 tctggttatc attcctgcca ttatcaatca aacgacaccc gttttctgga gtctcatggt
    15241 aactggcgga ctctgttata cagttggagc tggattttat gccaagaaaa aaccttattt
    15301 ccacatgatt tggcatctct ttatcctagc tgcgtccgta ctccaataca tcgctattgt
    15361 ttattacatg taaaaaagtt gagaaattca atctcaactt ttttctttac acatattgat
    15421 aaagtactgg tgcaagcgca catcatcagt caattctgga tgaaaagaac ttaccaacat
    15481 atttttttct tgggctgcaa caatttgatt gttcactgtt gctagaattt ctacaccctc
    15541 accaacacta ctgataatcg gaccacggat aaaggtcatt ggaatcttgc caactccctt
    15601 acattctgct tccgtgtaga aacttcctaa ttggcgccca taagcattac gctcgaccac
    15661 catatccata gttcctagat gactctcttt ctgagaagtg atttccttag ccaacaaaat
    15721 taagcccgca caggtcccaa acactggtaa gccagataga atggcttctc ggatgggaag
    15781 tagcatgttc tggtcacgta agagcttgcc catggttgta gactcaccac caggcaaaat
    15841 caaacccgac aagtcactct gatcttgctg aaaatcatct agatttctga gttctacact
    15901 ctcgacacct aattgatcta gcacttttgc atgttctgca aaggcccctt gcaaggccaa
    15961 tattccgatt ttcatctatt ttcctcgttc agccatgaga atttggattt cattttcatt
    16021 aataccaacc atggcttctc ctaaatcttc agagatttga gctaggattt gaggattacg
    16081 gaagttagtc acagccttaa caatggcact cgctcgttta acaggatctc ctgacttgaa
    16141 aatacctgaa ccgacaaaga ccccctctgc ccctaattgc atcattaacg cagcatctgc
    16201 tggcgttgca acacctccag cagcgaaatt tacaactggc aattttccat gttcatgaac
    16261 atattggacc aattctacag ggacttgcaa atccttggca gcaacataaa gctcgtcctc
    16321 acgtaagttt tgaatgcggc gaatttcctg attcatcata cgcatatgac gaacagcttg
    16381 gacgatatcc cctgtccctg gttctccttt ggtacgaatc atggaagcac cttcagcgat
    16441 acgacgcaag gcttcaccca aatccttagc accacagaca aaaggaactt ggaattcttt
    16501 cttatccaca tggaaacggt catcagctgg agatagaact tcactctcgt cgatataatc
    16561 aatttcaata gcctctaaaa tctgagcttc aacaaaatgc ccgattctga ccttagccat
    16621 tactggaata ctaaccgctt cttggatttc cttaatcatc tttgggtcgc tcatgcggga
    16681 aactcctcca gctgcacgaa tatcagccgg aattcgttcc aaggccatca cagctgccgc
    16741 accagcagct tctgcgatac gagcctgttc aggattctgt acatccataa taacaccacc
    16801 cttgagcatc tgtgccaagt ttttatttag ttcataacga ttttcagtca tttgttttat
    16861 cctcatcatt tgtattggta gctacctttt cattttaagt cagaacagaa tgaagcacaa
    16921 gataaaaaaa ctataattgt atggggacag attggctaaa aactatctga ccttaactta
    16981 aggccagata gctcattcat ttttattttt cagccgtaag ggcagccatt gtgatgtagt
    17041 tgtatggttt gttgaagtgt ggcaagaaga agaggtctgt caatgccaat ttatcaattg
    17101 tcacatgctc ttggatagca agtgagaaca tgtggattcc catgctaatt gcaatatcat
    17161 gtgaaaccat ttgggcacca agaatttcac ggctatcttt gtcaaagaca atcttaattg
    17221 ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg aagatcgtta aagcctgttt
    17281 cagttgcgtt gtaaccagca gctttcgctt tttcaagagt caaaccagtt gaaaccatgt
    17341 gaagaccgta gattgagata ccatttgaac cttgaacacc gattccttcc aattcatgtc
    17401 cacaagcatt gtaggcacca acgataccag tgcgaacagc atttgaagca agagcgatat
    17461 agcttgtatc tttacgagca ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc
    17521 ctgggataga tgtttcttgt ttcttgtcta caaggaaggc accgttgcgg aagagttcga
    17581 tcttaccatc tgcaagggct gtgtttggac gaaaaccaac tgcaaggata accatatcca
    17641 cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt accgtcacct tcgattgctt
    17701 taacagtttg acctagagcc aagcggatgt tgtgatcttc caagttcttc gccatcattt
    17761 gtgtgaagtc tttgtcatag taaccgttca agacagtatc aacgatatca acaaggacaa
    17821 cttcttttcc aagacgttca aaggcttcag caagttcaac accgatgtaa ccaccaccaa
    17881 caacggcgat acggtcgagg tgttggctct tgtcagaaag tttattgata acttcttcag
    17941 cattttggta caatttcacg aattgtacgt tttcaagagt tgctttaaac tcgcggtttc
    18001 ctttaacaat ttcaacacct tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa
    18061 tcaatttttc gtatgattct ttgtgctctt ttccttcaac ttccgctgta actactttgt
    18121 tatcatagtc gattgaaaga acaggtgagt tcatgtaaac tttagcacct ttagcttcca
    18181 atttttcttt atcagaatag aacaagcctt cagcaccgtc aatttgttca ccaatccaaa
    18241 gagccattcc acatcctagg aaagagatgt tagagttttg gtcaaataca acaatttcgt
    18301 tctcatttcc aaaattatcc aacatggtat taatacatgc tgtaccagcg tggttagcac
    18361 cgactacaac gattttactc ataaaaattt cctgccttca ttctaaattt accttactag
    18421 tataccattt accgttagcg tttacaaggg gggtactatt atttcagcat tttttatcaa
    18481 aaataattcc ccatttatcc tgttttcaag cctcatgaat tttatgagca tatttcttga
    18541 ctttttccaa attttgtttg tgaaaattct aactttatgg tattataata acatgaaaat
    18601 gaaatgtaag ggcttcaatt tagatgatta tttgatatta caacttattt tctataagag
    18661 aaaggagttg gtagcttgac tcttcgttca cattctgaac ggctaatggg gactactatc
    18721 actatttcat tagtggatga gcaagccgat atctttctcc aaaaatcctt tgacttgctc
    18781 aaagaacttg aataccgctt caacgccaat agtcaagaat ctgagttgat ggaaatcaat
    18841 tatcaagcag gaatatcccc cgtcacggtt catccagacc tgtttgagct gatttcactt
    18901 gggttagagc atagcctagc gctctctagc cacctcaata tcagcattgg tcccttaatt
    18961 caaacctggc gtatcggttt ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg
    19021 gtgctgcctc taatcaatcc tcatggtatc gagttagatt cttctacttc tactgtgttt
    19081 ttaaaacaga aaggaatgaa gattgatcta ggttgtttag ccaaaggata cagtgcggat
    19141 aaggttgccc aatttcttag gaaagagggg gtgacttctg ccttgatcaa tctgggaggg
    19201 aatatcctga ccattggaaa aaatcaggca agaggggata acccatggca aatcgggatt
    19261 caagacccag ccaatcctag gggaaatcat ttaatgacca tccctgttgt caataaatct
    19321 gtcgtgactt caggcattta tgaacgtcac ctgaccgtcg atggacaaga ttaccatcac
    19381 atttttgaca gtcaaacagg atatcctgtt gaaacggaac tagcgagtct aacaatcatc
    19441 tctgataaat cagtcgatgg cgaaatctgg acgactcgac tctttggaga aagacctgct
    19501 tctatcctct ggcaagtcga aagtttggag ggtatcgaag tcatcctcat cgataaagaa
    19561 ggccacctaa gctgttcttc aggaattcct actctataga gacaactgtt tcaatggaat
    19621 tttaaaattg tattatgtaa aaagagaaag gaaatctcat gttaaaactt attgctattg
    19681 ttggaacaaa ttcaaaacgt tctacaaacc gtcaattgct tcaatacatg caaaaacact
    19741 ttgctgacaa agctaaaatt gaacttgttg aaatcaaggc cattcctgtc ttcaacaaac
    19801 cagctgacaa gcaagtacct gctgaaatat tggaaattgc tgctaaaatc gaagaggcag
    19861 atggcgttat tatcggtact cctgagtatg atcactctat tccagctgtt ttgatgagcg
    19921 ctcttgcttg gttgtcttat ggtatttacc cacttttgaa caaaccaatc atgattacag
    19981 gtgcttctta cggtacgctt ggttcatctc gtgcccaatt gcaacttcgt caaatcttga
    20041 atgctcctga aatcaaggca aatgttcttc cagatgaatt cttgctctca cactctcttc
    20101 aagcatttaa cccaagtggc gacttggttg accttgatgt tatcaagaaa ttggatgcca
    20161 tctttgatga cttccgtatc tttgtaaaaa tcacagaaaa attacgtaat gcacaagaat
    20221 tacttcgcaa agatgctgaa gactttgact gggaaaattt gtaagatagg agaccaaaaa
    20281 gaatgaaatt tgttggactt gttggatcaa actacgatca atcatataac cgtaagctct
    20341 tggaatttat ccgtcgctac ttcaaactca aatttgaatt agaagttctt gaaattgacg
    20401 aagttccaat gtttaaccaa gatgaaaaat gggatgaaag tttccaatta cgttatttat
    20461 ataacaaaat tactcgtgca gatggtgtta tcattgctac tcctgagcat aaccacacta
    20521 tctcagcttc actcaaatct gtacttgaat ggctttcata cgaagttcat ccatttgaaa
    20581 acaagcctgt tatgattgtg ggtgcatcat actatgacca aggaacatca cgtgctcaag
    20641 ttcaccttcg taaaatcctt gatgctccag gtgttaatgc ctacacgctt ccaggtaacg
    20701 aattccttct tggtaaagct aaggaagctt ttgataacaa cggaaatatc accaacgaag
    20761 gcactgttaa attccttgaa acttgcttag ataactttgt taaatacgta ggagtcgttt
    20821 cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt ggattgtgga aaaccaatcg
    20881 ctacaaccat cacagaagtt gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa
    20941 tcactggtgc tgtttctggt gatacctatg tcaaattgga ccacggtatc ctaacagtta
    21001 accaaattga tatgttcttg aaagctatgc catttgaatt gacatacgct gacgacaaca
    21061 accaattcct ctactacaac aacgctcacc aagatccaga cactatgttc gctaaacgtg
    21121 taccacctca atcaggtagc cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta
    21181 tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta
    21241 cgatcgttcc aggttctcct gcaggtgtta tcaacactca caactaccaa gcaatgtact
    21301 atcctgatgg atcatacgct ggtatcaatg aaatcgtctt taacttccaa ccatggcttg
    21361 actggtacct aaaagagact ggtcaacgtt tgatgggtgg tagcggacca tttgctcctg
    21421 ctgccggagg tcatggagac gccgatgcta cttctggcgc ttctgattca ggggatgctg
    21481 gaggccacgg tggtgacgca gacgctacag ccggtgcaag ttactaatga tagtttttag
    21541 gaaccattat ggttcctttt ttagcgaaaa aagactagca aacacaaact gctagtctct
    21601 ttgttatcgt ttcatctatc tttgttaaaa gaaagagtac atattatgaa tttgggtcat
    21661 caagactacg gccatgtaat cctttttcac gttgtacttg gcgtagtttt tctggtgtaa
    21721 catcgtttcc ttcttcgtcc acaattttga ttccttcaat gtggtgacga acagcgcggc
    21781 gataaccttc gatgtactcc tcacgtagtt tggcttgttc cactttttct tctggtgtta
    21841 agccttctgt ttttttcttt ttagcaagct cattgatacg agcaattttt ttcggatcca
    21901 tttcttctcc tttgtaataa gataaagtcc gtttatcaaa ttttatttag tgttaatttg
    21961 gttaaaacaa gcaaacttag ctgctttctt ggttagttgt gacaagattg ccaaacgatt
    22021 ttgacggaca gcctgatctt cagccattac catagtattt tcaaagaaag catcaatgac
    22081 tgggctaagc gcaaagagtt gtttcaattg ctgacttgca ggtcctgata aaacgagtgt
    22141 ttctactgct tctgccaaag ctttttcttg gtcattctca aatagtgctg aatcaactgt
    22201 agcaacccct tctgccttct cagccaggtt aaaggcacga gaaagtgatt caacagatgg
    22261 tttaaaatct tcttccttgc ttacttctac gagagcactt gctgcttcca acatatctgc
    22321 cacaacaaag tttgaacctg caagaactgc ttccttgata tcttttggag tagagcccat
    22381 catcttatca acacgagcct tgataaagtc cataacctct gctttatttt cataagtcaa
    22441 actgtcaaat ttcaatgcat aaaggctatc aatcagctca tccatagcaa tgtgccaacc
    22501 aaaggcatcc aagatacgaa ccacaccttg agttgcacga cgaagggcat aagggtcatt
    22561 agaacctgat ggaatcaatc ctactgagaa gaaactcaaa atcgtatcca atttgtctgc
    22621 aatggctaga actgcgccga ccttgctctc tggaagttct ccttcagctg atgtaggcat
    22681 gtagtgttca cgaatagcag ctgccaccgc tggagtttca ccagcaagaa gggtgtattt
    22741 ttcacccata attccttgga gttcgtcaaa ttcaccaacc atacctgtca ataagtcaaa
    22801 cttgtaaatg gctgctgcac gagcaaggtc aactgtttca tccactgaca aatcagcttt
    22861 ttctgccaaa agtacagtga tttgacctgt acgaatcatg tgttcacgaa gggaaccaat
    22921 cttctcatgg aaggtgacat tgtttaattt ttcaacaaga tctgaaatca ccaatttttg
    22981 gtcttcacgc cagaagaatt ctccgtcttc caagcgggct accaagactt tttcatttcc
    23041 tttaatgaca tttttcaaac gctctgcgtt tccgttacga acagaaatga agtttggcaa
    23101 gagttttcca tcttgatcac gaacaacaaa gtaacgctgg tgttccttca tagaagtcac
    23161 caagacttct tctggaactt caaggtattt agcatcaaaa cttcccatga aggcagttgg
    23221 gtattcaacc aaattcaaga cttcattcag caaatccgca tcaatttcga tacgtacatc
    23281 atgttttgcc tcaatttcct tgatttggtc aacaatcatt tgctcacgtt cacatggatc
    23341 tgcgattaca aactgcttac gaaggtcttc ttcatagctc aatgctgact gaattttggt
    23401 ttctttcccc aagaaacgat ggccacggct cacacgactt cccttgatat caaggaaatc
    23461 caagtcaaac tcttgctcat ccaagagaac agttaaagtg tgaacagggc ggatgtattc
    23521 aaagctattt cccgcccagt gcatgctgac agggaaagtc aatgacttca atacatccac
    23581 aatgcctgga acaatggctt caactgcttg accaatttct tccttagtga catagacata
    23641 ttcttcaccc ttgatttcac ggaattcgat atcttcaaca gtcaagcctt ttccacggac
    23701 aaatccttga gctgctttgg tgaagtttcc atcactatcc aaggcaattt tctttgctgg
    23761 tcccttgaaa tcttctgtca aatcagactg tttgtctgat aaaccagtca cacgaacagc
    23821 caaacgacgt ggtgttgaga aggtttgaat ggcttcaaaa gacaggcgtt ttcccttgag
    23881 gaaggctgcc attttttcgc ctagttgttt ttcacttggt gtgacaacat aggctggtaa
    23941 ttcttcaaga ccgagttcta ctaataagtt ttttgtcatg ttttttcctt tacattttct
    24001 tcaatctttt ttgatatgca ccttaggtac tggggacgtc gctaactaac tctgtgagtc
    24061 tgtatggaaa tccaatgcta aatttatcaa gatttccaac aatctcatca aagtggattt
    24121 agctgactga tttttgaacc taaggtttca aaaatcccca cctaacagta cggcggtgca
    24181 tatccctcta gcaagtcttc gacttgcctc taacgatttt agagtacagt attactcact
    24241 attctgcgtc ttctgctaaa agtttaactc gtgtttcttc atccaaaagt gggtaaccta
    24301 ggcgtttgcg ttctgcaaca aaggttttgg ctacaacacg ggccaagtta cggatacgag
    24361 cgatatagcc tgcacgctct gttacagata cggcaccacg cgcgtcaagc agattaaagg
    24421 tatgtgaaca tttgagaaca tagtcatagg cagggtgtac caagccttct tctaatgcac
    24481 gaccagcttc tttttcaaac ttatcaaagt tttcaagcaa catttcttgg tccgaaattt
    24541 caaatgaata ttttgagtgc tcatactcag gctggataaa gatttctccg tattttacac
    24601 catcagccca ctcgatatca tagacagagt ctacttcttg aatgtaagaa gccaagcgct
    24661 ccaaaccata ggtaacttcc gcagtcacag ggccagttgc caatccaccg acttgttgga
    24721 aataagtgaa ctgagtgatt tccattccgt caagccaaac ttcccaacca agaccagctg
    24781 aaccagttga tgggttttcc cagttgtcct caacaaaacg aatatcgtgc tccaaaggat
    24841 tgattcccaa tttttccaaa gactcaaggt aaagttcttg gatatttgat ggagaaggct
    24901 tcatgaccac ctggaattgg tggtgttggt agagacggtt agggttttcc ccataacgac
    24961 cgtcagcagg acgacgtgat ggctctacat aagctgcatt ccatggctca ggtccgatag
    25021 cacgaaggaa agtgtaagga ctcattgttc ccgcaccttt ttcattatca taagcctgca
    25081 taagcataca accttggtca ttccaaaatt gttgcaaagt aaggatgatt tcctggaaag
    25141 tcaatttctt agacattgtt tactcctttt tatataaatt acttgcgaca tgaggctgcc
    25201 tcgtcgatca tacgaggcaa gacgagttag tactgcgtct agctcaggca ctctagtgct
    25261 gagcgtgggg cagtccgact gtaaggaggt ttctgccact gatgcagtga aatgttaatt
    25321 tctcagacat tgaatactcc ttaataaaaa ataatttctt gcgacacgag tctgcctcgt
    25381 cgattatacg aggcaagacg agttagtact gcgtctagct cagcacccta gtgctgagcg
    25441 tggagcagtc cgactgtaag gaggtttctg ccactgacgc agtgaaatgt caatttctta
    25501 gacattgttt actcctttag tttttatatt tctttttcaa ttaatttctg ctgaacaaac
    25561 caatctaaca agggaaaagt tttttctgta tttgcccata aatgataaga atctaagacc
    25621 gcttgtacac tacctaaatt ttctaccaac ttatctactg tcaaaaagct gcgccagtat
    25681 tcataaaaaa tacttgcata gttcttatca taagtcgaag aaccaaaatc attcaatgaa
    25741 tgccaaccat acttcttctg aaaaagttct acgagagatt gattacaaat tttttccgct
    25801 tgaaattcct cttctgtcaa gaaatacttg cgactaatat attcaaccat cccctcttcg
    25861 aaccagatat aagagtcata accatcaaaa tcatctaaaa aatgctccga ccaatgagct
    25921 aactcatgtc ctacaatctg taagaggaaa ttttcagata aagaatgata gtgactttct
    25981 attgcttgag tttgctgaga acactcgtag tccatcaatt gatacaaata caactctttc
    26041 caaacagcta aatcaggcgc cataaccatt cgtctattat ttgtataggc tggaacagcg
    26101 ctttccctaa taatctgtgt agcagcatta aaatctgacc aaataacggc ttgcggtaaa
    26161 tcacagactg caagttcatt ctttaaaaaa gattgataat ctttcaactt ttcagtattt
    26221 cttactacaa aatcacgaaa tgtagctagt tgactatcgt cttttacaag ataaaggttg
    26281 tccacggctc tcctttcttt cacacaatag actgaataag caaaagaacc acatctgaca
    26341 atcctaggtt gatttaacct aggggcgtca gaaacgcggt tccaccctaa tttattactt
    26401 cattgttttt gaaaatacta cagaaagcgc cagctcatta ttttgcccta cttggctccc
    26461 actatcccaa gctcgcttga agaacgccat aagactttct ttcttgctga ctattatatc
    26521 aaaaattaga ataatgtaca attcttttta tgattttcta gaaatccaca tcatcaactc
    26581 gtggagcacc cgattgaaca gcaatcgttt ttaaggtttc tctctcctca tgactcagtt
    26641 caattccaaa gcaatcaaga ttagcttgaa tacgagaggt tgtgacagat tttggaagtg
    26701 gtaaaaatcc ttctgccaag ctccaggcca aggctatctg agcaatcgat tttccgtgat
    26761 ttgctgcgat ttcttgcact tgcttgctat caaatagttc tccctgacca aaaggccccc
    26821 aagcttccaa taaaattccc ttttcacgac agtaagctac gacttgatct tgatacacac
    26881 ctggcgccaa gcgaacttga ttgaccgcag gaacgatagt tgcagtttca agcaaggcat
    26941 ccaaatgatg gggaagaaaa ttgctaacgc cgatagcacg gattttccct tcttgataga
    27001 ggtcttccat cgctctccaa acttccgcat tgcgagtttt ccatgcgtca ttttctctga
    27061 gcggttttgg gttcggccaa tgaatcaaat acaaatccaa ataatccaag cccagttttt
    27121 ctatagattt ttccaaagct tgacgagttt gctcataggt ttgctgacta ttccaaagct
    27181 tggtagttac gaacatttct tcacgtggaa ctccgctatc tttgattgct tgaccaacac
    27241 tttcttcatt ctgataaatc gccgccgtat caatatgacg ataaccagcc ttcaaggctt
    27301 ctaacactgc acgataggct tcttctccat ccttagcctt aaaagttcca aatcccaata
    27361 ctggaatttc tactccatta tttaattgat aggtattcat atgcttctcc ttctatttta
    27421 ttcatcaatt atagcataaa acatttttta agtagtacta tcttctgtaa aaaataagtc
    27481 tgtcaaatat ctaacagacc tattttttct tgcttattca tcacgactat agtacagctc
    27541 atgagctttt aggcgagtat tgagcatctc tggtatggtc acaaaggtat aaccttgatt
    27601 tttcaaatac tcaatgaccc ttggcaaggc attgactgtc ggactgtgaa tatcatgcat
    27661 caaaacgata gagccgttag ctacttgatg ctgaatttct gtcaaaatag atgcttcatt
    27721 tttactcttc cagtccagac tatccacatc ccacatgata aagctcaaat ccaagctatt
    27781 gcgaatatca tctgtaatag caccataagg tggacgcatg agtttagaac tagaacccag
    27841 cactttagtt agcacatcct cagtatcagt aatctgcttt ttagcttcat caagagagag
    27901 ttgcgagaga atcggatggc tccaactatg gtttccaaca acatgacctt cagattttat
    27961 cctcttcacc aagtcctcat tcccagaaac atttttccca agcacaaaga aagtcgcttt
    28021 aatatcatat ttagctaggg tctctaatac ctgcggggtc gttgctggat ttggaccatc
    28081 atcaaaggtt agagcgacaa ctttttgata tttcttatca aagtaagatt ggtacaaggc
    28141 cgcatctttt tcgagtaagt acgaagattg gataacatca aagaaagcag atactggcaa
    28201 ggctatctct tctaaatttt caaccacagg acttggataa aggataatct gactatcctt
    28261 gtaatcaaaa ttccatgcag acaagtcttg gtcagagaag ttttttacaa tctgctcact
    28321 ctggtcttgc tctatttttt tatcctctat gaaggaggtc aactctttta tcagctgttc
    28381 cttagcctta ctagcatctg aaaacagttg gtcaagtgta aaaggttgcc catcttctgt
    28441 taagtgaacc tttcctagac tggtcttttc agtctcttca accttaaaag caactaaatc
    28501 atagatttgt ttggtcacat tacgattaac gactcccttt aaacctgact cttcttgctc
    28561 tgtatagtag aaaacaagat tgtccttact ttctagcttg tccttaacat cttgatttat
    28621 caactcccta acagaggaaa tcactttctc cccttggaga ggataatagg caatcacttc
    28681 ggcttgcccc tgacgaaaat gctccttctg atttccctca ctcaattgat catctttctc
    28741 ttttttgagc gattcaatct tttgctcaaa acttttttgc tggtagatct taaaagcaat
    28801 aaatccgcct aataggcaaa tagaaattgc taaaatacca atcaaagcca ataatacatg
    28861 tctcgttttc ccgtgtctgc cacgtcctag tctactttta ttcatattta tatcataaca
    28921 aatttgagca ataatttcaa tgatacaatt tggcaatcca caattcctct agcaagccaa
    28981 agcatcttac atcaactcca acatccgtat ctgtagagat tatgtagttt tctatctatg
    29041 gaatttctag tagattgaag ctagaatagt agacctatac ttctaaaaca ttgttagaaa
    29101 tcgatttgat tgtcctgatc gatttgtcct gttctcattt cattttacta taaaactatg
    29161 aaaagctagg tcatctgaga agtaattact atcgacaatt gcgatagcgt atactggtgc
    29221 gatttgtttg tagctctggt gggtatcacc ttcacgttgg cgaatttttt ctaggttttg
    29281 attaacctga ctgcacagat aagcccatag gcgattgatg aaaaaattct gatgatgaac
    29341 ctgaatttcg atgataactt ggattccatt atctaactcc gccaagacgt ctatactagt
    29401 atagaaatcc tgcgctgagt agggcatgga aggcaagacg tgaatgttac ttccctccaa
    29461 aatcgtcaca ttttttgctg gcaagtccag catatcgcgg ataaattgac aaatcattag
    29521 ttgggctgat acccggatgt ctgagaatcc tccttttcct ccttctatta tagcacattt
    29581 ttaaatctag gtttgctaga ttctatgctt ctatctattt attcggaaaa gaaagctttt
    29641 cttcagaaga aagctaatag cttatttgaa attttctcct ctctgttgga tagtcccgtc
    29701 tatctatgtt ataatgaaag aaggatttaa aatcggaaaa ggagtattta tgctaaaatt
    29761 aggtgtcatc ggaactggcg ctatcagcca tcatttcata gaagcagccc ataccagtga
    29821 agaataccaa ctggtcgcaa tctattctag aaaactagaa actgcagcaa cctttgcttc
    29881 tcgctatcag aatatccaac tattcgatca attagaagtc ttcttcaaat cttcttttga
    29941 tttagtctat atcgccagtc caaactcctt acattttgct caggcaaaag ctgccttgtc
    30001 tgctggtaaa catgttattc tcgaaaagcc agctgtcact caaccacaag aatggtttga
    30061 tttgattcaa acagctgaaa aaaataactg ttttatcttt gaagcagctc gtaattacca
    30121 cgagaaagcc tttactacta tcaaaaactt tttagcagat aagcaagtgt taggagcaga
    30181 tttcaactat gccaaatact cttccaagat gcctgacttg ttgactggac aaacaccaaa
    30241 tgtcttttca aaccgttttg ctggtggagc cctcatggat ttggggattt atcccctcta
    30301 tgctgctgtt cgtctttttg gaaaagccaa tgacgcgact taccatgctc aacagcttga
    30361 taatagcatt gacctaaatg gagatggtct cctcttctac ccagactatc aagttcacat
    30421 caaggctgga aaaaacatca cttccaatct tccttgcgag atttatacaa cagatggaac
    30481 cttgactctc aacacgattg agcatattcg ctcagctatt tttaccgacc accaaggaaa
    30541 tcaagtccag cttcctatcc aacaggctcc tcatacgatg actgaggaag tcgctgcatt
    30601 tgcacacatg atccagcaac cagatctgaa tctctaccaa acttggctgt atgatgcagg
    30661 ctctgttcat gagctactat ataccatgcg ccagactgct ggcattagat ttgaggcaga
    30721 aaaatgaaaa ccaaactacc gactgaatgg caagaactga gtgaccaact cggtttccaa
    30781 gaattcaccc ccattcaaac tcaactattt gagccccttc ttgctggaga aaacctccta
    30841 ggagtgagcc aaaccggaac tggtaagacc ctagcgtatc tcctaccaag tcttctcaga
    30901 ctacaaaaga aaaaagccca acaactcttg attctagcac caaatacgga acttgctgga
    30961 cagatttttg atgtatgtaa aacgtgggca gaagctatcg gattgactgc tcaactcttc
    31021 ctttcaggtt caagtcagaa acgacaaatt gaacgtctta aaaaggggcc agaaattctg
    31081 attggaactc ctggccgtat ctttgaactc attaaactta aaaaaatcaa gatgatgaat
    31141 gtggaaacca tcatcctgga tgaatttgac caattactag atgattctca gattcacttt
    31201 gtagaaaaaa tcactcacta cgcacctcgt gaccaccaac tggtctacat gagtgccacg
    31261 accaagtttg accaagaaaa gattgtaccg aatacacgca ctattgatct ctctgatcaa
    31321 aaattggaca atatccagca tttctacatg caggtagacc aacgtcatcg agtggatatg
    31381 ctacgaaaac tggctcatgt agaggatttc cgtggtctag tcttcttcaa tagcctgtca
    31441 gaccttggga atgccgagga aaaactacag tatcgtgata tattggctgt ttccctcgct
    31501 agtgatgtta atgttaaatt tagaaaaatc atcttagaaa agtttaaaga taaccaacta
    31561 accctgcttc ttgcaactga ccttttggct cgtggaattg atatcgatag cctagaatgt
    31621 gtcgtaaact ttgatattcc tagagatagc gaaacctaca cacaccgtgc tggccgtact
    31681 ggtcgtatgg gcaaagaagg ttatgttatc actctcgtca ctcatccaga agaaatcaaa
    31741 aaacttaaaa agtttgcaag tatccgagaa attgtcctaa aaaaccaaga actctatatc
    31801 aaataaagcc ccattgctct atacacatcc agtgtatgaa gcttttttat aagcaattca
    31861 attttatact catctgcttt caaaaagcat tctagtccat ttccgattaa caatggactt
    31921 tatcacctcc ttctccagtt cttatatgac atcttggagt tgattcatga catcttccaa
    31981 agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat
    32041 ggggttcatc tctggtgtgt atggaggaat aaatgcaaag ccaatattag tcggaatctt
    32101 taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaaaat aatcatatgg
    32161 ataagcttgt gaaagctctt ctaaaaagac gttcatccac tcagtattac atccaccagc
    32221 tattaagaaa aatgattcgc ctgtatgggc atcaacagct ccataacaat agcgaaattc
    32281 tcgtatatag tgactatgga catgtggacc tactcctatt ggagaccaac aagatcccag
    32341 tttactgatt ctaccgaaac cagcctcatc ttggtacatc aagcgaacct tacgaaaacg
    32401 tctactatat ttaaatcgct ttcttgcctt cttgaattga gattttattt ttagacgcga
    32461 caatggtttg agcgtctgtt ttcctaggat gttctggacg tggcataata tttcgcca
//
LOCUS       DAVHSI010000021        31244 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.021, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000021 DAVHSI010000000
VERSION     DAVHSI010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31244
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.021"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..7991
                     /locus_tag="VVR21_001181"
     CDS             <1..7991
                     /locus_tag="VVR21_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6055072.1"
                     /translation="VEENVLRRDDQERISENERIFRNGEYGRDNRENQREYTESVGGR
                     DGLYEGISESDIRSDETGLSFKQRGAEQLRDVSGSIQGEETDRASDGYAETSNRIYES
                     REAETDGSLGDRGREPSAVQSDDFSPQRDDNQGNSGNLKENTDKEIREADKASFSLPE
                     NRSGQIKLTIPLTQNDIDSILVNGGNHEGERLPIIAEFSKGKTVEELGEYLKDTFRGG
                     NGLFLNGAEVSSWYSDKGIHLAYGTSAREDMTQILSWSDAVRRINELLENGEFATNVE
                     LLEAHDYERDRVSESLWYLYHDLSEEGKAQGYFDFMERGGEFPKETRQLSEALKNPDY
                     LKNVISEYSRFLAGYKENRDVLRFHYHKVDSLYQKLQELELTRKEYTSNLIEPPKVQG
                     FITEDEVLATISRGSGFDRGKERIIKFFKENHTLQEKANFLKDEYGIGGGSHAVSGAK
                     GSDEWHDAKGLKLQKNHCNDVFLTWSNVAKHIDELLSKNIYLEENKIESKTAIEEQKE
                     PSYYSKGDPYNLMTDEMLEKVPELYAQEDVALADKQVHAAYIIPFRSNWTWYMTEYDR
                     ESKDAFGLVLGIEPEWGYFNLEELKELNAQRLILEDFPKTFRELRDSELKKQMDEQEL
                     HNVFNGELSFEENIADLEAPEEVEESIQAEPFQATLLDYLKEKEEVELNEKEDRSSDE
                     FAVKEDDTVYFNHEEYKVREISKNPITGRNDLWLDPARQGNHQIPIVAFTDNEDLLRQ
                     VSLERPDFIIGDEVKYKGKDYTITRFDDMGNNLKTVTIKDNTEYLGGMITGSDVIPYR
                     KESEIGKIFENLTYAKPEKTFEEAEIKKNQAHNFKITEETLPSKLFPSERLNNNLEAI
                     SMLNRVESGERELDITAQEVLAKYVGWGGLADVFDESKDGQWKEARAFLKENLSSSEY
                     EAARESTLTSFYTPKTVIDGVYKTLSGMGFKQGNILEPSMGIGNFIGNLPDEMNQSKF
                     YGVELDSVSGRIGKLLYPESDIQVKGLEETGFSNNFFDVAIGNVPFGEYKVNDREYNR
                     NNFLIHDYFFAKSIDKVRNGGVIAFITSSGTMDKKDESVRRYLAARTEFIGAIRLPND
                     TFKGVAGTEVTSDIIFLKKRDSVLERDEDWIHLAEDENGLSYNKYFVDHPEQVLGSMR
                     EVSGRFGKTLTCEPIAYLGTEINMASLKERIEIAGERISKEAKYEEIELLDDEITSIP
                     ATDDVKNFSYTLIDDEVYYRENSLFIKKEVSDKNKEKIKDYLELNAALKDVIYKQKED
                     FNEEEIKASQEKLNEVYDNFSKKHGFVNNLSNTRALKEDSNFPLVSSIEILDEEENFK
                     AKGDIFSKRTITKAKIIDHVDTSLEALVLSVSEKGYVDFDYMGSLTGKDRPTLIEELR
                     GEIYLNIREEQNFYRPLSFNLEDGDLPFACANGSNSYKYGYVTKDEYLSGNIRDKIVI
                     VDSYLSKLRQTERELPHLGYEENGKEKELISYEMNRLEYQKTELTKVLPKELEASEIN
                     VRLGATWIPIKDIEKFIFETLKTPGYAKWDIKVKFSNLTSEWNVEGKSKDRGNDLAEM
                     TFGTNRVNAYKLIEDALNLKETKVFDQIVNPDGSKTSVLNKKETMLAGQKQELLKEEF
                     KNWIFNDQERRNRLVKLYNERFNSIRNREYDGSNLSFEGMNTEIDLRPHQRNAIARSL
                     YGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHLTGQIGREFMQLYPSA
                     NIMVADKKDFEPKNRKRFIGKIATGEYDAVVIGHTQFEKIPMSKEYQEKHIQDQIDEI
                     VNYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKLNDDFKKDDVITFEELGVDKLFVDE
                     AHGFKNLYLYTKMRNVAGIGQSEAFKSSDMFMKCRYMDEMTGGKGVVFATGTPVSNSM
                     TELYTMQRYLQYESLKKNNLEHFDSWASTFGETQSSFELSPEGTGYRVKTRFSKFYNL
                     PELMSMFKEVADIQTADMLNLPTPEANYEVIKTEPSEEQKEILKSLSERADDVRNRVV
                     EPDVDNMLKITNDGKKLALDQRLINPLLPDNPDSKVNVCVKNVFAIWDKTKENRSTQL
                     LFSDMSTPKGDGEFNIYDDIREKLVSMGIPKEEIAFIHEANSDKQKDELFAKVRKGEV
                     RILMGSTQKMGAGTNVQNKLIAMHDLDVPWRPADLEQRAGRIVRQGNENEKVNIYRYV
                     TENTFDSYLWQTIENKQKFISQIMTSKTPVRVAEDVDESSLNYAEIKALATGDPKIKE
                     KMDLDNEVTKLKMLEANYKSNRYRLEDKVAKNYPEEIARTEKLIEAVKKDIASVEPKA
                     EGEEKFTSITIAGEKITDKKLAGERLLEAISKVKINESKVIGRYRNMDLEVSYNFFTN
                     EHNFSLNGAAKHSGELGTSVDGNITRLDNALEKMPEKLNRLEEKLISTKEQLENAKEE
                     LKKPFEKADELKTKVLRLAELNKLLDMGEVEEKRNDNPLVEDVKRAIIDFCNREYEEN
                     HSYDEFNTLYPDLKHIGIAYTNTPDERHGIQYELNLEEKTWTQYIDDTPIKTESFDYE
                     SKGENEALRNMKNEMEMSSFSDLVYVDSEDLKAATGLEIDDEGNFYDPLSKDLDNDGI
                     PDRYDNDFKDSDYFESTYDVEDNLHSKEETAQKSEDKPSILGQIRAYQNESKTEEKQK
                     TKEQEFLR"
     gene            8034..8693
                     /locus_tag="VVR21_001182"
     CDS             8034..8693
                     /locus_tag="VVR21_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6055073.1"
                     /translation="MDYKTMRNQIEDMVNDNHKDFVKAIISLEKGINNESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLVNIVGNIVGEVDVVEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNIRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQAEDKEKPKEKKEANKEAE
                     R"
     gene            complement(8767..10098)
                     /locus_tag="VVR21_001183"
     CDS             complement(8767..10098)
                     /locus_tag="VVR21_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU6055074.1"
                     /translation="MAITKIHPIKSTLNLAISYIVNGEKTDEQILVSTHKCHQETAHT
                     QFLRTRNDAGTNGTVLARHLIQSFLPGETSPEIAHQIGLELCKKILKDEYEFVLSTHI
                     DKGHIHNHIIFNNVNMVTGKCYQSNKKSYHQIRYQSDKLCKDNNLSVIDEFYESYKRK
                     YKTNGKSWYENEQAKRGSSWKSKLQFDIDRLIKQSKDWEEFLKKMAELGYEIKHGKHI
                     AFKPKDKQKFTRAKTIGEDYTEERLRERITENQSIKAPPVKKRIGNVINMNTNAKVKE
                     SKGYEYWATKHNLNTMAESVVFIREHGIKSVKQLDECIKKSAEERQNLQDKIKKIDKD
                     MQLLSDTMEQVHTVKKYRAYYKEYKANPSDKAFFEEHKSEITRYETDLAKLKKSYSKL
                     PDSKDILDKLDKLQEKKNTLMQEYSSTKSTMDELYQIRKNYGIYMGKEMER"
     gene            complement(10104..10454)
                     /gene="mobC"
                     /locus_tag="VVR21_001184"
     CDS             complement(10104..10454)
                     /gene="mobC"
                     /locus_tag="VVR21_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEU6055075.1"
                     /translation="MANRMRNERLEIKLTEEEKALFEEKRKLAKCKNMSHFIRKCVLE
                     KEIYQVDLEPFRDLQGLLSNATNNINQIAKRVNSTGIIYKDDINDMKKQIEHFSKELW
                     QIHSLLLNRTSGGD"
     gene            10794..11384
                     /locus_tag="VVR21_001185"
     CDS             10794..11384
                     /locus_tag="VVR21_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU6055076.1"
                     /translation="MKEEKQKVGQIRKKEIREAAKKCFLNKGFQLTTMEDVITEVGMS
                     RGGVYHHYGNTNEMFKDLMLDGNDYRNNLINEYLKNNRGKDKYQQMGDILVDKSLADT
                     ELMRLYTLLLQAKKYNQDLEKLYQELKLNTTNELSLIAKQLGIKADIFGDGFLVNYIN
                     AMILSSEVLCARNSFSQHKKYIKETMVNYIVDIDKR"
     gene            11396..11983
                     /locus_tag="VVR21_001186"
     CDS             11396..11983
                     /locus_tag="VVR21_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6055077.1"
                     /translation="MSKRLEVKDLINIGLFSVLGFVFMMIGSFLGMVPVLMPVVPFAQ
                     GVLVGPVNMLYSTKIKKRGMVFIQSLLIALVYVAMGHGPWALLTAVIAGIIAEVILKS
                     GEYTDVNKARLAFSVAPLCTLGNWLPIFISRNEYVKQMLERGYKQEFIDKMLSVMPNW
                     IIVVMAIGGIIGAYIGCSIGMAFLKKHFKKAGMEK"
     gene            12004..12705
                     /locus_tag="VVR21_001187"
     CDS             12004..12705
                     /locus_tag="VVR21_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6055078.1"
                     /translation="MTIKLDFRTKLFMTIVLSYVMVLGNIQVKYFLQALIISVIPIVL
                     LINTKHTRVAIIGMATLVFVYGADRFLMKLEYSPLVAILLILVMVVKKILPAFLMGKY
                     TILTSNVGESIYSLKKMKCPDEIAIPLTVMVRFFYAARIDYSQIKKAMRLRGLTLKKL
                     IKNPILLFEYRLVPLLMCLSKTADDLTVSAMTKGLAVNQKRTSISESRIGGIDCIFFV
                     IMVWAIYLYIRGKYA"
     gene            12698..13255
                     /locus_tag="VVR21_001188"
                     /pseudo
     CDS             12698..13255
                     /locus_tag="VVR21_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844950.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            13588..13902
                     /locus_tag="VVR21_001189"
     CDS             13588..13902
                     /locus_tag="VVR21_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6055079.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            13918..14304
                     /locus_tag="VVR21_001190"
     CDS             13918..14304
                     /locus_tag="VVR21_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6055080.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            14333..15718
                     /locus_tag="VVR21_001191"
     CDS             14333..15718
                     /locus_tag="VVR21_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6055081.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            15721..15873
                     /locus_tag="VVR21_001192"
     CDS             15721..15873
                     /locus_tag="VVR21_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6055082.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            15896..17101
                     /locus_tag="VVR21_001193"
     CDS             15896..17101
                     /locus_tag="VVR21_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6055083.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            17144..17365
                     /locus_tag="VVR21_001194"
     CDS             17144..17365
                     /locus_tag="VVR21_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055084.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            17482..17979
                     /locus_tag="VVR21_001195"
     CDS             17482..17979
                     /locus_tag="VVR21_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6055085.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            17954..18460
                     /locus_tag="VVR21_001196"
     CDS             17954..18460
                     /locus_tag="VVR21_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6055086.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            18444..20891
                     /locus_tag="VVR21_001197"
     CDS             18444..20891
                     /locus_tag="VVR21_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6055087.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            20894..23071
                     /locus_tag="VVR21_001198"
     CDS             20894..23071
                     /locus_tag="VVR21_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6055088.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYDPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            23068..24069
                     /locus_tag="VVR21_001199"
     CDS             23068..24069
                     /locus_tag="VVR21_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6055089.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            24066..24998
                     /locus_tag="VVR21_001200"
     CDS             24066..24998
                     /locus_tag="VVR21_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6055090.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            25243..25359
                     /locus_tag="VVR21_001201"
     CDS             25243..25359
                     /locus_tag="VVR21_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6055091.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            25375..27294
                     /gene="tet(M)"
                     /locus_tag="VVR21_001202"
     CDS             25375..27294
                     /gene="tet(M)"
                     /locus_tag="VVR21_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU6055092.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDYLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            27413..27580
                     /locus_tag="VVR21_001203"
     CDS             27413..27580
                     /locus_tag="VVR21_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU6055093.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(27640..27993)
                     /locus_tag="VVR21_001204"
     CDS             complement(27640..27993)
                     /locus_tag="VVR21_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6055094.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            28498..28920
                     /locus_tag="VVR21_001205"
     CDS             28498..28920
                     /locus_tag="VVR21_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6055095.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            28917..29147
                     /locus_tag="VVR21_001206"
     CDS             28917..29147
                     /locus_tag="VVR21_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6055096.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            29608..29811
                     /locus_tag="VVR21_001207"
     CDS             29608..29811
                     /locus_tag="VVR21_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEU6055097.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            29893..31110
                     /locus_tag="VVR21_001208"
     CDS             29893..31110
                     /locus_tag="VVR21_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6055098.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT        10613 a         5168 c         6528 g         8935 t
ORIGIN      
        1 aggtagaaga aaatgtactt cgacgagatg atcaggaaag aattagtgaa aacgagcgaa
       61 ttttccgaaa tggagagtac ggacgagata atagagaaaa tcaaagagaa tacactgaat
      121 cagttggagg aagagatgga ctttatgagg gaatatccga atccgacata cgcagtgatg
      181 agactggatt atctttcaaa cagcgaggag cagagcaact tcgagatgtt agtggatcta
      241 tacaaggaga agaaactgat agggcatctg atggatacgc agaaacaagc aatagaattt
      301 atgagagcag agaagccgaa actgatggca gcttgggaga tagaggacga gagccatccg
      361 cagtacaaag cgatgatttc agccctcaaa gagatgacaa tcaaggaaat agtggaaatc
      421 taaaagaaaa tacggataaa gagataagag aagctgacaa ggcttctttt tctttacccg
      481 aaaacagatc aggacagatt aaacttacaa tacctcttac acaaaatgat attgacagta
      541 ttcttgtaaa cggtggaaac catgagggcg aaagacttcc tatcattgct gaattttcca
      601 aagggaaaac agtagaagaa ttaggagaat accttaaaga tacctttaga ggcggaaacg
      661 gtttatttct taatggagca gaagtatctt cctggtattc ggataaaggt attcatttag
      721 cttatggaac ttctgcaaga gaagatatga cgcaaatttt aagctggagt gatgctgtaa
      781 gaagaatcaa tgagcttttg gaaaatggag agtttgccac aaatgtagag cttttggaag
      841 cacatgacta tgaaagagat agagtttcag aatccttatg gtatttatat cacgatttaa
      901 gtgaagaagg gaaagcacag ggatattttg actttatgga aagaggaggt gagtttccta
      961 aagaaacaag acagttatcg gaagctctta aaaatcctga ctatctaaaa aatgttattt
     1021 ccgagtacag ccgtttttta gcaggataca aagaaaatag agatgtacta aggtttcatt
     1081 atcacaaggt agatagcctt tatcaaaaat tgcaggagct tgaacttaca agaaaggaat
     1141 atacttctaa ccttatcgaa cctccaaagg tacaaggctt tattacagaa gatgaagtcc
     1201 ttgctacgat ttcaagagga agcggctttg atagaggaaa agagcgaatt attaagtttt
     1261 tcaaagaaaa tcataccttg caggaaaaag cgaatttctt aaaagatgag tatggaatcg
     1321 gtggaggttc tcatgctgtt tcaggagcaa agggaagtga tgaatggcat gatgcaaagg
     1381 gactgaaatt acagaagaat cattgtaacg atgtttttct tacatggtca aatgtagcaa
     1441 agcatataga tgagctgctt tctaaaaata tttatcttga agagaataaa attgaaagca
     1501 agacagcgat agaagaacaa aaagagccaa gttattactc taaaggcgat ccatataatc
     1561 taatgactga tgaaatgctt gagaaagttc ctgaacttta tgcacaagag gatgtagctt
     1621 tagcggataa acaggttcat gcagcatata tcattccatt tagaagtaac tggacttggt
     1681 atatgacgga atatgacagg gaaagtaaag acgcttttgg acttgtgctt ggaatagagc
     1741 ctgaatgggg atattttaat cttgaagagc taaaggaact aaatgcacaa aggctcattt
     1801 tagaggattt tccaaagacc tttagagaac ttagagacag tgagcttaaa aagcagatgg
     1861 atgagcagga gcttcacaat gtatttaacg gagaacttag ctttgaggag aatattgcag
     1921 accttgaagc acctgaagaa gtagaagaaa gcatacaggc agaacctttt caggctacct
     1981 tattagatta tctaaaggaa aaagaagaag tagagcttaa tgaaaaagag gacagatctt
     2041 cagatgagtt tgcagttaaa gaagatgata ccgtctattt taatcatgag gagtacaaag
     2101 taagagagat ttccaaaaat ccaatcacag gaagaaatga tttgtggctt gatcctgcaa
     2161 ggcaaggtaa tcatcaaata ccgattgtag cctttactga taatgaggat ttattaagac
     2221 aagtaagtct tgaaagacct gactttatca taggtgatga agtgaaatat aagggaaaag
     2281 actataccat cacaagattt gatgatatgg gaaataacct aaagacagta acgattaagg
     2341 ataataccga atatcttgga ggcatgatta caggctccga tgttattcct tatcgtaagg
     2401 aaagtgagat tggtaaaatc tttgaaaatt tgacttatgc gaaacctgaa aagacttttg
     2461 aggaagcaga gataaagaaa aatcaggctc acaatttcaa gattacagaa gaaacgcttc
     2521 cttcaaagtt atttccaagt gagaggttaa acaataacct tgaagcaatc tctatgctca
     2581 acagggtgga aagtggagaa cgagagcttg atattacagc tcaggaagtt ttagcgaaat
     2641 atgttggttg gggtggactt gctgatgtct ttgatgaaag taaggatgga cagtggaaag
     2701 aggcaagagc cttcttaaag gaaaatctat cgtcatcaga atatgaagct gcaagagaat
     2761 caaccttaac gagcttttac acaccgaaaa ccgttataga tggcgtatat aagacgcttt
     2821 caggtatggg atttaaacag ggaaatatcc ttgaaccgtc aatgggtatc gggaacttta
     2881 tcggtaattt acctgatgaa atgaatcagt caaagtttta tggagtagag cttgattcgg
     2941 taagcggtcg tattggaaag ctgctatacc ctgaaagtga tatacaggta aagggacttg
     3001 aagaaacggg attttccaat aacttcttcg atgtagcaat cggaaatgtt ccatttggag
     3061 agtataaggt aaatgacagg gaatacaatc gtaataactt tcttatccac gattatttct
     3121 ttgccaagtc cattgataag gtaagaaacg gcggtgttat cgcctttatt acatcttcag
     3181 gaacaatgga taaaaaagac gaaagtgtaa gaagatatct tgcagcaaga accgaattta
     3241 taggagcaat cagacttcca aacgatacct ttaagggtgt tgccggcaca gaagtaactt
     3301 cggatattat cttcttaaag aaaagagata gtgtattaga gcgagatgaa gattggatac
     3361 accttgcgga agatgaaaat ggactttcat ataacaaata ctttgtcgat catcctgagc
     3421 aggtgcttgg ttctatgcgt gaagttagcg gaaggtttgg gaaaacactc acttgtgagc
     3481 cgatagctta tttaggtaca gagataaaca tggcttcatt aaaggagcgt atcgagattg
     3541 caggagaaag aatttcaaaa gaagccaagt atgaagaaat agagctactt gatgatgaaa
     3601 taacttctat ccctgcaacc gatgatgtaa agaacttctc ttataccttg attgacgatg
     3661 aagtctatta cagagaaaac tcacttttta tcaaaaagga agtatcagac aagaataaag
     3721 aaaaaatcaa ggattacctt gagctgaatg ctgccttaaa agatgtgatt tacaagcaga
     3781 aagaagattt taacgaagaa gaaatcaagg cttcacagga aaaactaaat gaagtatatg
     3841 acaacttttc taaaaagcat ggctttgtca ataacctaag caataccaga gccttaaaag
     3901 aggatagcaa cttcccgctt gtttcctcca tagaaatcct tgatgaagaa gaaaatttca
     3961 aggcaaaggg agatattttc tccaaaagaa ccattacaaa agccaaaatc atagaccatg
     4021 tggatacctc tttagaagct cttgttttat cggtatctga aaaaggatat gtggactttg
     4081 actatatggg aagtcttacc ggaaaagaca gaccaacttt aattgaggag cttcgagggg
     4141 aaatctatct aaacatcaga gaagaacaaa acttttacag accactttcc tttaacttag
     4201 aagatggcga tttacctttt gcctgtgcta atggcagtaa ttcatataaa tatggctatg
     4261 taacaaaaga tgaatatttg agtggaaata tcagggataa gattgtcata gtagacagct
     4321 acttatcaaa gctaagacaa acggaaagag aacttcctca tcttggctat gaagaaaatg
     4381 gcaaagaaaa agagctgata agctatgaaa tgaaccgttt ggaatatcaa aaaacagagc
     4441 ttacaaaagt tcttccaaag gaattggaag caagtgaaat caatgtgcgt cttggtgcaa
     4501 cttggatacc tattaaagat attgagaaat ttatttttga aacgctaaaa actccgggat
     4561 atgccaaatg ggatattaag gtaaaatttt ccaaccttac aagcgaatgg aatgtagaag
     4621 gaaaaagcaa ggacagagga aatgaccttg cagaaatgac ctttggtaca aatagagtta
     4681 atgcctataa gctgattgaa gatgccttaa acctaaaaga aacaaaggta tttgaccaga
     4741 ttgtaaatcc ggatggctct aaaacttctg tcttaaataa aaaagaaacc atgcttgcag
     4801 gacaaaagca ggagttatta aaagaagaat ttaagaactg gatatttaac gatcaggaaa
     4861 gaagaaaccg tcttgtaaaa ctgtataatg agcgttttaa ctcaatccgc aacagagaat
     4921 atgacggaag caatctctct tttgagggaa tgaatacaga gattgactta agacctcatc
     4981 aaagaaatgc catagcaaga agcctttatg gaggaaatac cttgcttgcc catgtagtag
     5041 gaagtggaaa gacctttgaa atggtagctt ccgcaatgga gagtaaaagg cttggaatgt
     5101 gcagtaagtc cttgtttgtt gtaccaaatc atttaacagg gcaaatcggg cgtgagttta
     5161 tgcagctata tccatcggct aacattatgg tggctgataa gaaagatttt gagccgaaaa
     5221 acagaaagag atttattggt aagattgcca caggggaata tgatgcggtt gttatcggac
     5281 atacgcagtt tgaaaaaatc ccgatgagta aggaatatca ggaaaagcat attcaagatc
     5341 agattgatga aatcgtaaac tatgtagaag aatacaagca tgatagaaat cagaacttta
     5401 ccgtaaaaca gcttgaaaag acaaagaaaa aactggaaac aaggcttgaa aaattaaatg
     5461 atgattttaa gaaagacgat gtgattacct ttgaggagct gggagttgat aagctctttg
     5521 ttgacgaagc acatggcttt aaaaaccttt atctctatac caaaatgaga aatgttgcag
     5581 gtatagggca gtcagaagcc tttaagtcct ccgatatgtt tatgaaatgc agatatatgg
     5641 acgaaatgac aggcggcaaa ggcgtggtct ttgccacagg aacgcctgta agtaactcaa
     5701 tgaccgagct ttataccatg cagcgttatc ttcagtatga gagcttaaag aaaaataatc
     5761 tggagcattt tgactcttgg gcttccactt ttggagaaac acaatcctcc tttgaattat
     5821 cgcctgaagg tacaggatat agggtgaaaa cgagattttc aaagttctat aacttgcctg
     5881 agcttatgtc tatgtttaag gaagttgctg atattcagac ggcagatatg cttaatcttc
     5941 ctacacctga agctaactac gaggttatta agacagagcc aagtgaggaa caaaaggaaa
     6001 ttctaaagag cctctctgaa agagcagatg atgtcagaaa tagggttgta gagccagatg
     6061 ttgataatat gcttaagatt accaacgatg gtaagaaact tgccttagat cagcgtttaa
     6121 tcaatccact tcttcctgat aatcctgata gcaaggtcaa tgtatgcgtg aaaaatgtat
     6181 ttgctatttg ggataagaca aaagaaaaca ggtcaacaca gctacttttt tccgatatgt
     6241 ctactccaaa aggagatgga gaatttaaca tctatgatga tattagagaa aagctcgtat
     6301 ctatgggaat accgaaagaa gaaatcgcct ttatccatga agcgaattcc gataagcaaa
     6361 aagatgaact ctttgcaaag gtaagaaaag gcgaagttcg tatcttaatg ggttcgacac
     6421 agaagatggg tgctggtaca aatgtgcaaa ataaactaat tgcaatgcat gatttagacg
     6481 taccatggag acctgctgac ttagagcaaa gagcagggag aattgtaaga cagggaaacg
     6541 aaaatgagaa agtaaatatc tatcgttatg ttacagagaa tacatttgac agctacttat
     6601 ggcagacgat agagaataag cagaaattca tttctcagat tatgacttca aagactcctg
     6661 ttcgtgttgc ggaagatgtg gacgaaagct ctcttaacta tgcagagatt aaagctcttg
     6721 caacgggtga tccaaagatt aaagagaaga tggatttgga caacgaggtt acaaaactta
     6781 aaatgcttga agcaaactat aagtctaacc gttacagatt agaggataaa gtggcgaaaa
     6841 actatcctga agaaatcgca agaacggaaa agctcataga agctgttaag aaagatatag
     6901 caagtgtaga acctaaagcg gaaggtgagg aaaagtttac ttctattact attgcaggag
     6961 aaaagattac cgataagaaa ttagccggag aaagactgct tgaagcaatt tcaaaggtta
     7021 aaatcaatga aagcaaggtt ataggaaggt atagaaatat ggatttagag gtaagctata
     7081 acttctttac caatgagcat aactttagct taaacggtgc tgcaaagcat tcaggagagc
     7141 ttggaacaag tgtggacggt aacattacaa gacttgataa cgctcttgag aaaatgcctg
     7201 agaaattaaa taggcttgaa gaaaaactta tcagcacaaa ggaacaactt gaaaatgcca
     7261 aagaagaact caaaaagcct tttgaaaaag ctgatgagct gaaaactaag gtattaagac
     7321 ttgcagaact gaataagctc cttgatatgg gagaagtgga agaaaagaga aatgacaatc
     7381 cacttgtaga agatgtaaaa agggcaatca ttgacttctg taacagagag tacgaagaaa
     7441 atcacagcta tgatgaattt aataccttgt atcctgactt aaagcatatc gggatcgcct
     7501 ataccaatac accagatgaa aggcatggga ttcagtatga actgaactta gaggagaaaa
     7561 cttggacaca gtacattgat gatactccta tcaaaacaga gagctttgat tacgagagta
     7621 aaggagaaaa tgaagctcta aggaatatga aaaatgaaat ggaaatgtcc tcttttagtg
     7681 atttagtcta tgttgattct gaagatttaa aagcagcaac agggcttgaa attgatgatg
     7741 aaggcaactt ctatgatccg ctttccaaag acctcgataa tgacggtatt cctgacagat
     7801 atgacaatga ctttaaggac agtgattatt ttgagtcaac ttatgatgtg gaggacaatc
     7861 ttcatagcaa agaagaaacc gcacaaaaat ctgaggataa gccatctatt ttaggacaga
     7921 taagagctta tcaaaatgaa agcaaaactg aagaaaagca aaaaacaaaa gaacaggaat
     7981 ttttaagata aggggagggt aacctccctt ttgccatgaa aggagataaa aacatggatt
     8041 acaaaacaat gagaaatcaa atagaagata tggtaaatga taaccacaag gactttgtaa
     8101 aggcgattat aagcctagaa aaaggtatca acaatgaaag tgctttagat aagctctatg
     8161 acgcttatat ggacaatgac agccttaatt tgctgcatga ggaatttgac tatatgattg
     8221 aggatttaag agaacagggg cagataaaag acctgcctta tgttcaggaa gaaaaggata
     8281 accttgtaaa tattgtagga aatatcgttg gagaggtcga tgtagttgaa agggaaaata
     8341 aaaacggaga agcctttaag gtagcgaatt tctccgtagt atccaaagac gatgaaggga
     8401 ataaggtata tcataattgt tcggcatacg gagaaaaaag cgatattcca aaggacttta
     8461 agcagggaga ttttgttaag ctctttggac aaatcagaac atccattgat gataacggca
     8521 aggagcatag caacatcagg atactttctt caaagctact aaaggcaaag gaacaaatga
     8581 aaggacaaga agaaaagaaa gaatctgtac ttggagctat caagaaatat caggcggaag
     8641 ataaggaaaa gccaaaagaa aagaaagaag caaacaaaga agctgagaga taaatttacg
     8701 gtcggtgtgg tcttagggct gcaccgactg ttttttattt gtcttgaaaa aagaggagag
     8761 aaaaaattat ctctccatct ccttgcccat gtaaatccca tagttctttc gtatttgata
     8821 aagctcgtcc atagtagatt ttgtagaaga atactcttgc attagggtat tctttttttc
     8881 ttgcaattta tcaagtttat ctaaaatatc ttttgaatca ggcagctttg aataggattt
     8941 tttgagtttt gcaagatctg tttcgtagcg tgtgatttca gacttatgct cctcaaaaaa
     9001 tgccttatca gaaggatttg ctttatattc cttgtagtag gctcgatact ttttaacagt
     9061 atgaacttgt tccatcgtat cagaaagtag ttgcatatcc ttgtcaattt ttttgatttt
     9121 atcttgtaag ttctgtcttt cttcagcact tttcttgatg cattcatcaa gctgcttaac
     9181 ggatttaatg ccatgttctc tgatgaaaac aactgactca gccattgtat ttaagttatg
     9241 ttttgttgcc caatattcat agcctttgct ctctttcact ttggcattgg tattcatatt
     9301 gatgacattt ccaatgcgtt ttttgacagg tggggcttta attgattgat tttctgtaat
     9361 acgctctctt aatctttctt cggtataatc ctcaccaatc gtcttagccc ttgtaaattt
     9421 ctgcttatct tttggcttaa aggctatatg ttttccatgc tttatttcat aaccaagttc
     9481 cgccattttc tttagaaatt cttcccaatc tttagactgt tttatcaaac gatcaatgtc
     9541 aaattgaagc ttgctcttcc aagaactgcc acgctttgcc tgttcatttt cataccatga
     9601 cttgccattt gttttgtact ttctcttata gctctcgtag aactcatcaa tcacagaaag
     9661 gttattatcc ttgcatagtt tatcgctttg atacctgatt tggtggtagc ttttcttgtt
     9721 ggattgatag cacttgccag ttaccatatt tacattattg aagatgatat gattgtggat
     9781 atgcccttta tctatatggg tagataagac aaattcgtac tcatccttta atatcttttt
     9841 acatagttca agaccgattt gatgtgcaat ttcaggactt gtttctcccg gtaaaaagga
     9901 ttgaataagg tgtctggcaa gaacagttcc gtttgttcct gcatcatttc gtgttcttaa
     9961 aaattgggta tgagcagttt cctgatggca tttatgagtg cttactaaga tttgctcgtc
    10021 tgttttttct ccattaacaa tatatgaaat ggcaagatta agggttgatt ttatgggatg
    10081 tatttttgta atagccataa aatttaatca cctccagaag ttctgttaag aagcagtgaa
    10141 tgtatctgcc acaactcttt tgagaaatgt tcaatctgct ttttcatatc gtttatatca
    10201 tctttgtaga ttatgccggt cgaatttaca cgctttgcaa tctgatttat gttgtttgta
    10261 gcgttggaaa gcaagccctg taaatctcta aatggctcta aatccacttg atatatttcc
    10321 ttttctaaaa cgcacttgcg aatgaaatgg ctcatatttt tgcatttcgc aagttttctt
    10381 ttctcctcaa aaagagcctt ttcttcttca gttaatttaa tttcaagtct ttcatttcgc
    10441 attctatttg ccataggtaa atcctccttt gaatgtattt cgggtcttag ggtacaccct
    10501 aacaagttaa aaattgataa aaaaagaagc agatcccaaa gggctgcttc atcaattttt
    10561 tcgtaagtgt ccgtacactt actgtgcttg ctacaaaaga atgaattaga tagcaagcat
    10621 taagcatcta ttaactttta gataatttta caataaaatt tgctgaaagt caaagctata
    10681 aagaagattg ttattcaaac ttaaaagtta gttgacatta actatcattt atgataaaat
    10741 aaaattcgac agtagtgtcg gtttttatta cgatatgaaa tgaggtcttt gttttgaaag
    10801 aagaaaaaca aaaagttgga caaattagaa aaaaagagat tcgagaagct gcaaagaaat
    10861 gctttctaaa taaagggttt caacttacaa caatggaaga tgttatcaca gaggtaggaa
    10921 tgagtagagg aggtgtctat catcattatg gtaatacaaa cgaaatgttt aaagacttaa
    10981 tgcttgatgg taatgattat agaaacaact tgataaatga gtatttaaaa aacaatcgag
    11041 gaaaagataa atatcagcaa atgggtgata ttttggttga taagtcgctg gctgatacag
    11101 aattgatgag attgtataca ctccttttac aagcaaaaaa atataatcag gatttggaaa
    11161 aattgtatca agaattgaaa cttaatacga ctaatgagct aagtttaatc gccaagcagc
    11221 ttggaattaa ggcagatata tttggtgacg gttttttagt gaattatatc aatgcgatga
    11281 tattaagttc tgaagttctc tgtgcaagaa attctttttc acaacataaa aaatatataa
    11341 aagaaacaat ggtaaattac attgttgata ttgacaagag atagggaggt ttaaaatgag
    11401 taaacgatta gaagtaaagg atttaatcaa cataggatta ttttctgtat taggttttgt
    11461 atttatgatg attggatcat ttttaggaat ggttccagtt ttaatgccgg ttgttccatt
    11521 tgcacaggga gttttagtag gacctgtaaa tatgctgtat tccacaaaga ttaaaaaaag
    11581 aggaatggtg tttattcaat cattacttat tgcattagta tatgttgcta tgggacatgg
    11641 accttgggca ttattgaccg ctgttattgc tggtattatt gctgaagtta ttttgaaatc
    11701 aggagaatat acggatgtta ataaggcaag attagcattt tctgttgctc cactttgcac
    11761 attaggaaat tggttgccaa tttttatatc aagaaatgaa tatgtcaagc agatgttaga
    11821 gcgaggatat aaacaagaat ttattgataa gatgcttagt gtaatgccga attggattat
    11881 tgtcgtaatg gcaataggtg gaattatagg agcatatatt ggttgtagta taggtatggc
    11941 tttcctaaaa aaacatttta aaaaggctgg tatggaaaaa taaggattca taaggagtta
    12001 aggatgacaa tcaaacttga ttttcgtaca aaacttttta tgacaatagt tctttcatat
    12061 gtgatggttt taggcaatat tcaagtaaag tatttcttgc aagcccttat aatatccgta
    12121 attccgatag tgcttttaat aaatacaaaa catacaagag tagctattat tgggatggct
    12181 actcttgtgt tcgtttatgg tgctgataga tttttaatga aattagaata cagtcccttg
    12241 gtagcgattt tactgatatt agtaatggtt gttaagaaaa tacttcccgc atttttaatg
    12301 gggaaatata ccatactcac atcaaatgta ggggaaagta tttattcatt gaaaaaaatg
    12361 aaatgtcccg atgaaatagc aataccattg actgtgatgg ttcgtttctt ttatgccgca
    12421 aggattgatt atagccagat aaaaaaagcc atgcgtttga gaggactaac gcttaaaaag
    12481 ttaataaaaa atccaattct attatttgaa tatagattag tgccactatt gatgtgtttg
    12541 tctaagacgg cagatgattt aacagtatcc gcaatgacaa aagggttagc tgttaatcaa
    12601 aagcgaacaa gtattagtga atcacgcatt ggtggcattg attgcatatt ttttgtgata
    12661 atggtatggg caatctattt atatataagg ggtaagtatg cttagtttac aaaatttagt
    12721 attaaagttt gatggagaaa gcatattaga aaatgtaaat ctaaatttca aacccggaga
    12781 ggtaactgtt ataacgggac actcaggtac ggggaaaagt agtttgttaa aagtaataaa
    12841 cggcattatt cccgaatatg attgtggaga tgtaaaagga gatgttttat acaaggacaa
    12901 atctttatta gggatgagta tattagaacg atccaagttt atatctacag tgtttcaaaa
    12961 tcctaaaaca cagttttatt gtatcaattc cacagatgaa ttggcttttc aattagaaaa
    13021 tagatgtata gaaagaaatt taattttaga taaaatacac tattattcag atgttttagg
    13081 tagtaaagat ttgttagaca agaatatttt tgaactgtcc ggtggagaga agcagttaat
    13141 tgctataact gctagtggaa tttcagaaaa tgaaattatt cttttagatg aaccatcttc
    13201 atctttggat tatgaatcaa ttaagaactt aaaaagagct attattgagc taaaaatagc
    13261 ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa ggtcaaaacc
    13321 actcaattta ctactaattt actacttatg aatgagcttt gatacgacga tttatccttg
    13381 aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg tagacacttc
    13441 aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt atgaaaacaa
    13501 aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat tcattcagcc
    13561 aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc caacatggaa
    13621 aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg aagaatcaac
    13681 ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca aagagcagat
    13741 gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt tgaggaacgt
    13801 gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac tcgtggtttt
    13861 acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag aggaaaaatg
    13921 atgagattag caaatggcat tgtattagat aaagacacga cttttggaga attgaaattc
    13981 tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc agatgaaatc
    14041 aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca agtaagtatt
    14101 cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact tatcaatccc
    14161 attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg gtatatcaag
    14221 gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc acaagcaaag
    14281 aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc gcatgaaaca
    14341 gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta cgatagcgtc
    14401 actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa tccagcagat
    14461 caactggcag gattttaacc tatcacaagc agataagatt gacattccct atttaattat
    14521 cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca aacgggttcg
    14581 ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga tacttgaaaa
    14641 caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata gtgctggtcg
    14701 tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa atggcttgat
    14761 acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac acttggaaaa
    14821 gaaattagag agtggcttgt actgtgagct gacggataaa gagttaaagg attcctatgt
    14881 ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg aagtagaagc
    14941 taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata agctccctca
    15001 tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga cactgattga
    15061 agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg ctgatcttgc
    15121 ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc tttcttgcat
    15181 tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga tgaagaacta
    15241 taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa tctttgatga
    15301 atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta tgaataagct
    15361 gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg cttgtcaacg
    15421 tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca gagtggcttt
    15481 aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac aaaaggattt
    15541 cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg tcatatcaga
    15601 gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta aaaagttatc
    15661 caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg tggactgatc
    15721 ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct aacagggggg
    15781 tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta caagggattt
    15841 acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt tttgattgga
    15901 gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac gcttggctta
    15961 tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt atctaagcga
    16021 tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt gggaagctct
    16081 ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa gaattcgctt
    16141 tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac tgtcctattt
    16201 tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag gcgacatatt
    16261 cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag gtcgtgggtg
    16321 cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt tctttatgga
    16381 cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg ataagacagg
    16441 gattttaaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta tctccgtctt
    16501 ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa aggaatgtat
    16561 gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta tctatgaaaa
    16621 ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag taaaaaaccg
    16681 ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt tactcgtcta
    16741 tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt ttgtagataa
    16801 agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt ggtttattgg
    16861 gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct tccaaaggac
    16921 gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta aacttgatga
    16981 aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga cagaccgaca
    17041 caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa caaaaaaata
    17101 actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt ttggacaaaa
    17161 cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa tcgttgtgat
    17221 tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt taattattgc
    17281 gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt tactagagct
    17341 attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat aagtggtttt
    17401 cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt ttgaatctct
    17461 acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa tttaggcaaa
    17521 tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt tgaggaagtc
    17581 aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga ctacgagtta
    17641 ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg ggaaatggta
    17701 tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca tttttcaagc
    17761 attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg tgatgatatg
    17821 tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt accagctagt
    17881 cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc aggaacgttt
    17941 atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta cattactact
    18001 ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt atgaaaggat
    18061 tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa aggtactgta
    18121 ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt
    18181 cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca tgatagaggg
    18241 agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac
    18301 ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacc
    18361 aaagctgacc tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat
    18421 tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa aacaatctcg
    18481 tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac aattactcat
    18541 ttctaagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt atcgcacaaa
    18601 atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata cgttctgcac
    18661 aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat gacaaaatcg
    18721 accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac taccgtttct
    18781 ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg
    18841 aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg atgggcgatt
    18901 ttgttagtat gagtaatgat gaaatcctgc gttttcagaa gatggaaaag ctcttagaaa
    18961 ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc ggctatctga
    19021 ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac catctatcaa
    19081 agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag cctactcgct
    19141 gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa accgtctatg
    19201 tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc tctgaaatct
    19261 tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat gtggaaattg
    19321 tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg
    19381 ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa gctctggaaa
    19441 gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac aagctgtctt
    19501 atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt aatgaagtga
    19561 aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat atgctcggct
    19621 tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt caatacgtga
    19681 cctctgattt cctcgctggt ttaggttttg gtgctactca aatgctgggg gaaaatgagg
    19741 ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg
    19801 ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt gttggttcgc
    19861 tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg ctttatgggg
    19921 cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa accttgccag
    19981 agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac aaaggcttac
    20041 ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct attgatattc
    20101 tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc cttagaaaag
    20161 ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt gaggaattac
    20221 gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt tttacagact
    20281 atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc agcttagaaa
    20341 aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa acttcctttg
    20401 aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt agtacctttg
    20461 ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta gacgaagcat
    20521 ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt cgggctggtc
    20581 gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc ttagatgaaa
    20641 aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt aacgagatta
    20701 aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag aagcgattgc
    20761 gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc ggtgtgatac
    20821 agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca cctgtgcgaa
    20881 aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact ggacgctgaa
    20941 acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca tttttctttt
    21001 agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg tcaatgtggc
    21061 aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg tggataatag
    21121 ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca tgtatggact
    21181 atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg cgacaggtta
    21241 cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt ccattggtaa
    21301 gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg gtttctatgt
    21361 tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata cgggactgat
    21421 aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg tgtttatcct
    21481 atcggcttcc tttattgcct acgatcccga ctacattaaa aaaatcaatg acttttcatc
    21541 agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc attccgatag
    21601 tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac aggttcagca
    21661 accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta ttgaccgtgt
    21721 ggaaagcctg ctctccacca gcccagattc caacaatggc gaagatagag aaaaaattgt
    21781 tgcggaagaa attgaagaca gaagcaatac caatctaacc attacaaaga ccattaaccg
    21841 tttaggtaca gtcttcttcc tatttgtctt caatattggg atttccatat ttgtattcct
    21901 attaacagga atcatgattt tctcgcaggt actttttatc atctatgcta tgtttctgcc
    21961 tgtgagcttt attttaagca tgattccatc atttgatggt atgtcaaaac gagccataac
    22021 aaagctcttt aataccattt tgacacgagc tggaatcaca ttgattatta cgacagcatt
    22081 tagtatttca accatgctct ataccttatc ggctggttat ccgttctttt tgattgcttt
    22141 tctacagatt gtgacctttg caggaatcta cttcaagctg ggcgatttaa tgagtatgtt
    22201 ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa aacctcgtat
    22261 gcttatgcac gctcacatgc accgtctaca gcggaaactt ggacgttcca tgactactct
    22321 aggggctggg tctgccattg ttacaggtaa aaaaggacag tcgggttcgg ggagttctgc
    22381 aaggacacaa gcagatcact cccgaccaga cggaaaggaa aaatcaacac ttggaaaacg
    22441 tatcggtcaa accatcggta cagtagctga taccaaagac agaatggtag acactgctag
    22501 tggtttgaaa gaacaggtta aagatttgcc gaccaatgca agatatgcag tatatcaagg
    22561 aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt agtatttctc aaaccaaagc
    22621 ggacagagcc agtggacgca aggaacagca ggaacaaagg cgaaaaacca ttgcgaagcg
    22681 tcgctctgaa atggaacagg tcaaacagaa aaaacagcct gcttcttctg ttcatgaaag
    22741 accgactaca agacaagaac aatatcatga tgaacagacc tcaaaacagt ctaatattca
    22801 gacttcatat aaggaatctc aacaagccaa acaagagcgt ccagcagtta agtccgattt
    22861 ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg ttcaaaagcc
    22921 agcaacttca accactacag cagatagaac ttcacaacgt ccaatcacaa aagaacgtcc
    22981 gtctactgtt caaagagtac cactacaaaa tacaagaagt agaccaccaa tcaaaaccgc
    23041 caccattaag aaagtcggta agaaaccatg aagttgaaaa ctttagtgat tggtggttct
    23101 ggattattct tgatggtctt ctcactgctt ctgtttgttg ccattttatt ttcagatgaa
    23161 caggacagcg gaatttccaa tattcattat ggaggtgtga atgtttccgc agaagtgctg
    23221 gctcataagc ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga atatgtcaac
    23281 atacttcttg cgattataca ggtggaatcg ggcggtactg cggaagatgt tatgcagtcc
    23341 tcggaatccc tcggtcttcc acctaattca ttgagtacag aagaatccat taagcaaggt
    23401 gtgaagtatt tcagtgaatt attagccagt agcgaaaggc tcagtgtaga tttagaatcg
    23461 gttatccagt cctacaatta tggtggtggt ttcttagggt atgtggctaa tcgtggaaat
    23521 aaatatacct ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg cgaaaaagtg
    23581 tcttacccca atcccatagc catacctatc aatgggggct ggcgatacaa ctatggcaat
    23641 atgttttatg tgcaactggt aacgcagtat cttgtcacaa cagagtttga tgatgatacg
    23701 gtacaagcca tcatggacga agcactgaaa tatgagggct ggcgatacgt ttacggtgga
    23761 gcttccccga ctacttcttt tgattgtagc ggactgacac aatggacgta tggaaaagct
    23821 ggaattaact taccacgaac cgcacaacag caatatgatg tgacccagca tatcccacta
    23881 tcggaagcac aagctggcga tttggttttc tttcattcta cctataacgc tggctcttat
    23941 attactcatg ttgggatata ccttggcaat aaccgtatgt ttcatgcagg cgacccaatc
    24001 ggttatgccg acttaacaag cccctactgg caacagcatt tagtgggagc aggacgaatc
    24061 aaacaatgag aaaggaagat ttaatgatga aatttagaaa aaatcagaat aaagaaaaac
    24121 agataccaaa ggaaaagaaa cctcgtgtct ataaggtcaa tcctcataaa aaggttgtga
    24181 ttgccttgtg ggtactttta gggcttagtt tcagctttgc gatattcaag cactttacag
    24241 ctatagatac tcatactatt cacgaaacaa ctatcataga aaaggaatac gttgatactc
    24301 atcatgtaga aaattttgta gagaactttg cgaaagtcta ctattcatgg gagcaatccg
    24361 ataagtccat tgataatcga atggaaagtc taaaaggcta tctgacagat gaacttcaag
    24421 ctctcaatgt tgatacagta cgcaaagata ttcctgtatc gtcttctgta agaggatttc
    24481 agatatggac ggtagagcca actggcgaca atgagtttaa tgtaacctac agtgtagacc
    24541 agctcattac agagggagaa aatacaaaga ccgtccactc tgcttatata gtgagtgtct
    24601 atgtagatgg ttctggaaat atggtactgg ttaagaatcc gaccattacc aacataccta
    24661 agaaatcaag ttataaacca aaagccattg aaagtgaggg gacggttgat tccattacaa
    24721 ccaatgaaat caatgagttt ttaacgacgt tcttcaagct ctatcctaca gcgacagcca
    24781 gtgaactttc ctactatgtg aatgacggga tattaaaacc aatcggaaaa gagtacatct
    24841 ttcaagaact ggtaaatcct attcacaatc gtaaggataa tcaagtcacg gtatcgctga
    24901 cagtggagta tatcgaccag cagaccaaag caacgcaggt atctcaattt gatttggtac
    24961 ttgaaaagaa cgggagtaat tggaagatta tagaataaca aatattggta cattattaca
    25021 gctattttgt aatcacgtac tctctttgat aaaaaattgg agattccttt acaaatatgc
    25081 tcttacgtgc tattatttaa gtatctattt aaaaggagtt aataaatatg cggcaaggta
    25141 ttcttaaata aactgtcaat ttgatagtgg gaacaaataa ttggatgtcc ttttttagga
    25201 gggcttagtt ttttgtaccc agtttaagaa tacctttatc atgtgattct aaagtatccg
    25261 gagaatatct gtatgctttg tatgcctatg gttatgcata aaaatcccag tgataaaagt
    25321 atttatcact gggattttta tgcccttttg ggtttttgaa tggaggaaaa tcacatgaaa
    25381 attattaata ttggagtttt agctcatgtt gatgcaggaa aaactacctt aacagaaagc
    25441 ttattatata acagtggagc gattacagaa ttaggaagcg tggacaaagg tacaacgagg
    25501 acggataata cgcttttaga acgtcagaga ggaattacaa ttcagacagg aataacctct
    25561 tttcagtggg aaaatacgaa ggtgaacatc atagacacgc caggacatat ggatttctta
    25621 gcagaagtat atcgttcatt atcagtttta gatggggcaa ttctactgat ttctgcaaaa
    25681 gatggcgtac aagcacaaac tcgtatatta tttcatgcac ttaggaaaat ggggattccc
    25741 acaatctttt ttatcaataa gattgaccaa aatggaattg atttatcaac ggtttatcag
    25801 gatattaaag agaaactttc tgccgaaatt gtaatcaaac agaaggtaga actgtatcct
    25861 aatatgtgtg tgacgaactt taccgaatct gaacaatggg atacggtaat agagggaaac
    25921 gattaccttt tagagaaata tatgtccggt aaatcattag aagcattgga actcgaacaa
    25981 gaggaaagca taagatttca gaattgttct ctgttccctc tttatcatgg aagtgcaaaa
    26041 agtaatatag ggattgataa ccttatagaa gttattacta ataaatttta ttcatcaaca
    26101 catcgaggtc cgtctgaact ttgcggaaat gttttcaaaa ttgaatatac aaaaaaaaga
    26161 caacgtcttg catatatacg cctttatagt ggagtactac atttacgaga ttcggttaga
    26221 gtatcagaaa aagaaaaaat aaaagttaca gaaatgtata cttcaataaa tggtgaatta
    26281 tgtaagattg atagagctta ttctggagaa attgttattt tgcaaaatga gtttttgaag
    26341 ttaaatagtg ttcttggaga tacaaaacta ttgccacaga gaaaaaagat tgaaaatccg
    26401 caccctctac tacaaacaac tgttgaaccg agtaaacctg aacagagaga aatgttgctt
    26461 gatgcccttt tggaaatctc agatagtgat ccgcttctac gatattacgt ggattctacg
    26521 acacatgaaa ttatactttc tttcttaggg aaagtacaaa tggaagtgat tagtgcactg
    26581 ttgcaagaaa agtatcatgt ggagatagaa ctaaaagagc ctacagtcat ttatatggag
    26641 agaccgttaa aaaatgcaga atataccatt cacatcgaag tgccgccaaa tcctttctgg
    26701 gcttccattg gtttatctgt atcaccgctt ccgttgggaa gtggaatgca gtatgagagc
    26761 tcggtttctc ttggatactt aaatcaatcg tttcaaaatg cagttatgga ggggatacgc
    26821 tatggctgtg aacaaggatt gtatggttgg aatgtgacgg actgtaaaat ctgttttaag
    26881 tatggcttat actatagccc tgttagtacc ccagcagatt ttcggatgct tgctcctatt
    26941 gtattggaac aagtcttaaa aaaagctgga acagaattgt tagagccata tcttagtttt
    27001 aaaatttatg cgccacagga atatctttca cgagcataca acgatgctcc taaatattgt
    27061 gcgaacatcg tagacactca attgaaaaat aatgaggtca ttcttagtgg agaaatccct
    27121 gctcggtgta ttcaagaata tcgtagtgat ttaactttct ttacaaatgg acgtagtgtt
    27181 tgtttaacag agttaaaagg gtaccatgtt actaccggtg aacctgtttg ccagccccgt
    27241 cgtccaaata gtcggataga taaagtacga tatatgttca ataaaataac ttagtgtatt
    27301 ttatgttgtt atataaatat ggtttcttgt taaataagat gaaatatttt ttaataaaga
    27361 tttgaattaa agtgtaaagg aggagatagt tattataaac tacaagtgga tattgtgtcc
    27421 tgtatgtgga aataaaacac gattaaagat aagggaagat actgaattaa aaaaattccc
    27481 cctctattgt ccgaaatgca gacaagaaaa tttaattgaa ataaagcagt tcaaagtaac
    27541 tgtgattaca gagccagacg caaagacgca gagccgataa aatgagatta atacaatctc
    27601 attttatcgg ctctttccgt tatgtatgga ttcttttaat tagtcttcga tgtttcttgc
    27661 ttcgttgata ccgctggcta aagattccat taaggatagt tctttgtctg taaagctatc
    27721 catgtatttc tctatctgta atcgtcgggt gctttttacc aagttattag caggtaagaa
    27781 aaattcatca acggaaacat gaagtaacga tacaaggtca taaagaactt gtatgctggg
    27841 gtgttgccct ttattttcaa tattagttaa gtaccgtggg tcaatttcaa tcaatgctcc
    27901 cacttgttca cgagttaaac ctcgtttcaa tcgagcttct ttaatggcta aaccaaaggc
    27961 tctaaaatca tatttatctt cttttttacg catagtagac cacctctata cattttattg
    28021 ttcctactga attaaaaaca ggtatagaaa aacgtgttat atggtttata ggtttatatt
    28081 taataaaaag cactactaaa cgccaataaa aaaaaccgtt atatggtagt gctatttacg
    28141 ctgttaaaat attgtatatt acttccaaat ggcggtttgt tggaggtcaa cgtcgccatg
    28201 aagtacatca tatacaataa atttccttac attgggttct tgtcaaaaaa agtcgtctat
    28261 ctgcaataga taagtacgtc caccaatgtg gttttataaa tcatatagat agaataacag
    28321 aagcatgtaa acagagaaat aaatctgttt atatgctttt ttggctattc agaacttttt
    28381 tacaaagttt atttatcagt aatgcaacaa atcccccttt cacattggga ctaagagtga
    28441 aaggagataa acgagcaagg ctcacttcct ttcctagaca gaaagggggt gagaaacatg
    28501 aaaccatctt cttttcagac cacaatagaa aatcagtttg actatatctg taaacgtgct
    28561 atggaagacg agcgaaagaa ttatatgctt tatctttcaa ggattgcaaa gcgtgaggtg
    28621 tccttttcgg atgttggcga ttatcttgtt agccagtttg cgacaacaga taactattca
    28681 actgactttc agatttttac actcaatggg ttatcagtag gcgttgaaaa tgatttgttg
    28741 agtgaagcat tacgtgagtt gccagacaag aaacgtgaaa ttctactgct gttttacttt
    28801 atggacatga gcgattcaga aattgcagac ctgttgaaat tgaaccgttc tactgtctat
    28861 cggcatagaa ccagtggact agccttaatt aaaaagttta tggaggaatt tgaagaatga
    28921 aaacacaata tcctatgatt ccctttcctc tcattgtaaa ggcaacagat ggcgataccg
    28981 aagcgattaa ccagattcta catcattaca gagggtacat aacgaagcgt tccctacgac
    29041 ttatgaaaga tgaatatggc aatcaaagta tggtcgttga tgaagtctta cgtggaagaa
    29101 tggaaaccag actgattaca aagattttgt catttgaaat taagtaatat cctctctcct
    29161 ttcgtggaag cgtgctaaac cattccacgc ttcccgaaca gggaggtttg ttattccacc
    29221 aaagcatatt gagctttcaa tgtgttttga taggctaacg agccattgtt ctttgaaaac
    29281 tgaataaaag taatcgaata cgtttcgata agaaaagagc caacggaact aaccgccatg
    29341 acctatctta taaagatagc gagcgattca tgttagtgat ccgagaagca atctttagca
    29401 ggattgcctg caacgacatt cttatcgtga taatgatact cccatacagt caatagtccg
    29461 agcgtgataa aaccgtcgca ggcaatgagt atggctacat gagaaccatg caggggtgga
    29521 actcccgtga gctttgctaa agctgttcga ttgctggtaa aacaactttt atgaaatcca
    29581 aataagtgat ttggaaagga ggattttatg aagcagactg acattcctat ttgggaacgt
    29641 tataccctaa ccattgaaga agcgtcaaaa tattttcgta ttggcgaaaa caagctacga
    29701 cgcttggcag aggaaaataa aaatgcaaat tggctgatta tgaatggcaa tcgtattcag
    29761 attaaacgaa aacaatttga aaaaattata gatacattgg acgcaatcta gcgtcgccaa
    29821 agggtcttgt atatgataaa atagtattaa gtcgtatcaa ggctctttcc ataaaggaaa
    29881 ggagcaaatg ccatgtcaga aaaaagacgt gacaataaag gtcgaatctt aaagactgga
    29941 gagagccaac gaaaagacgg aagatactta tacaaatata tagattcatt tggagaaccg
    30001 caatttgttt actcgtggaa acttgtggct acagaccgag taccagcagg aaagcgtgat
    30061 tgtatctcac ttagagagaa aatcgcagag ttacagaaag acattcatga tggtattgat
    30121 gttgtaggaa agaaaatgac actctgccag ctttacgcaa aacagaacgc tcaaagacca
    30181 aaggttagaa aaaacactga aactggacgc aaatatctta tggatatttt gaagaaagac
    30241 aagttaggtg taagaagtat tgacagtatt aagccatcag acgctaaaga atgggctatt
    30301 agaatgagtg aaaatggtta tgcttatcaa accatcaata actacaaacg ttctttaaag
    30361 gcttcattct atattgctat acaagatgat tgtgttcgga agaatccatt tgactttcaa
    30421 ctgaaagcag ttcttgatga tgatactgtc cctaagaccg tactaacaga agaacaggaa
    30481 gaaaaactgt tagcctttgc aaaagctgat aaaacctaca gcaaaaatta tgatgaaatt
    30541 ctgatactct taaaaacagg tcttcgtatt tcagagtttg gtggtttgac acttccagat
    30601 ttagattttg agaatcgtct tgtcaatata gaccatcagc tattgagaga tactgaaatt
    30661 gggtactaca ttgaaacacc aaagaccaaa agtggcgaac gtcaagttcc tatggttgaa
    30721 gaagcctatc aagcatttaa gcgagtgtta gcgaatcgaa agaatgataa gcgtgttgag
    30781 attgatggat atagtgattt tctctttctt aatagaaaga actatccaaa agtggcaagt
    30841 gattacaacg gcatgatgaa aggtcttgtt aagaaataca ataagtataa cgaggataaa
    30901 ttgccacaca tcactccaca tagtttgcga catacattct gtaccaacta tgcaaatgca
    30961 ggaatgaatc caaaggcatt acagtacatt atgggacatg ctaatatagc catgacgctg
    31021 aactattacg cacatgcaac attcgattct gcaatggcag aaatgaaacg cttgaataaa
    31081 gagaagcaac aggagcgtct tgttgcttag tagtacaaat gaatttacta cttatttacc
    31141 acttctgaca gctaagacat gaggaaatat gcaaagaaac gtgaagtatc ttcctacagt
    31201 aaaaatactc gaaagcacat agaataaggc tttacgagca ttta
//
LOCUS       DAVHSI010000022        29930 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.022, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000022 DAVHSI010000000
VERSION     DAVHSI010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29930
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.022"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..745
                     /locus_tag="VVR21_001209"
     CDS             <1..745
                     /locus_tag="VVR21_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF389 domain-containing protein"
                     /protein_id="HEU6055099.1"
                     /translation="LSPISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNI
                     VPGVAIATALMPPLCTVGYAIASANPKFIIGSSYLFLINCSFIVIATYIGVRLMMVKK
                     HYFKDNEEDSKMRRILLLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNIL
                     KKTYSKKTHTLKLTISGNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEEL
                     VEYFFQYIKDKEAKEKEKANKFDTESEEQ"
     gene            912..2999
                     /gene="topA"
                     /locus_tag="VVR21_001210"
     CDS             912..2999
                     /gene="topA"
                     /locus_tag="VVR21_001210"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU6055100.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGNVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3105..3464
                     /locus_tag="VVR21_001211"
     CDS             3105..3464
                     /locus_tag="VVR21_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU6055101.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            3557..4189
                     /locus_tag="VVR21_001212"
     CDS             3557..4189
                     /locus_tag="VVR21_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU6055102.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQLEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            4233..4889
                     /locus_tag="VVR21_001213"
     CDS             4233..4889
                     /locus_tag="VVR21_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU6055103.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            4908..5540
                     /locus_tag="VVR21_001214"
     CDS             4908..5540
                     /locus_tag="VVR21_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU6055104.1"
                     /translation="MNFQLAEYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            5568..6002
                     /locus_tag="VVR21_001215"
     CDS             5568..6002
                     /locus_tag="VVR21_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU6055105.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6014..7051
                     /gene="leuB"
                     /locus_tag="VVR21_001216"
     CDS             6014..7051
                     /gene="leuB"
                     /locus_tag="VVR21_001216"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU6055106.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7048..7317
                     /locus_tag="VVR21_001217"
     CDS             7048..7317
                     /locus_tag="VVR21_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU6055107.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            7321..7680
                     /gene="leuD"
                     /locus_tag="VVR21_001218"
     CDS             7321..7680
                     /gene="leuD"
                     /locus_tag="VVR21_001218"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU6055108.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            7842..8466
                     /locus_tag="VVR21_001219"
                     /pseudo
     CDS             7842..8466
                     /locus_tag="VVR21_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            8629..10560
                     /locus_tag="VVR21_001220"
     CDS             8629..10560
                     /locus_tag="VVR21_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU6055109.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKV
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLGKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            10547..11863
                     /locus_tag="VVR21_001221"
     CDS             10547..11863
                     /locus_tag="VVR21_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU6055110.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12038..13024
                     /locus_tag="VVR21_001222"
     CDS             12038..13024
                     /locus_tag="VVR21_001222"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU6055111.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13088..13159
                     /locus_tag="VVR21_001223"
     tRNA            13088..13159
                     /locus_tag="VVR21_001223"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13121..13123,aa:Arg,seq:ccg)
     gene            13342..14040
                     /locus_tag="VVR21_001224"
     CDS             13342..14040
                     /locus_tag="VVR21_001224"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU6055112.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14031..17570
                     /gene="smc"
                     /locus_tag="VVR21_001225"
     CDS             14031..17570
                     /gene="smc"
                     /locus_tag="VVR21_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU6055113.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRSI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEVQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLDSEEVALKTLQDEMARLIESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEKELNRLSDGDWQADKEKCQERLATIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            17567..18361
                     /locus_tag="VVR21_001226"
     CDS             17567..18361
                     /locus_tag="VVR21_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6055114.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            18361..19179
                     /locus_tag="VVR21_001227"
     CDS             18361..19179
                     /locus_tag="VVR21_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6055115.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19183..20460
                     /gene="ftsY"
                     /locus_tag="VVR21_001228"
     CDS             19183..20460
                     /gene="ftsY"
                     /locus_tag="VVR21_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU6055116.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVNPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(20504..21991)
                     /locus_tag="VVR21_001229"
     CDS             complement(20504..21991)
                     /locus_tag="VVR21_001229"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU6055117.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDDKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGVPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(22140..22880)
                     /locus_tag="VVR21_001230"
     CDS             complement(22140..22880)
                     /locus_tag="VVR21_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6055118.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(22880..25045)
                     /locus_tag="VVR21_001231"
     CDS             complement(22880..25045)
                     /locus_tag="VVR21_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU6055119.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            25217..26170
                     /locus_tag="VVR21_001232"
     CDS             25217..26170
                     /locus_tag="VVR21_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6055120.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLMDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLDQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVTMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            26247..28235
                     /gene="uvrB"
                     /locus_tag="VVR21_001233"
     CDS             26247..28235
                     /gene="uvrB"
                     /locus_tag="VVR21_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU6055121.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            28245..28808
                     /locus_tag="VVR21_001234"
     CDS             28245..28808
                     /locus_tag="VVR21_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055122.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYKINGNS"
     gene            28774..29283
                     /locus_tag="VVR21_001235"
     CDS             28774..29283
                     /locus_tag="VVR21_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055123.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIDDVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            29336..29800
                     /locus_tag="VVR21_001236"
                     /pseudo
     CDS             29336..29800
                     /locus_tag="VVR21_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091533.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
BASE COUNT         9242 a         5334 c         6665 g         8689 t
ORIGIN      
        1 tctttctccc atttcgtatg ctagttcgga gattgttgct agaacctctc cgactatttg
       61 ggatgttctc attgcttttg taggagggat agcaggtatt attggtgcta ggaaaaaaga
      121 gaccaataat attgttcctg gtgttgctat tgcaaccgcc ttgatgcctc ctctttgtac
      181 agtaggttat gctattgctt ctgctaatcc aaaatttatc ataggctcct cttacctatt
      241 cctcatcaat tgtagcttta ttgtcattgc gacttatata ggtgttaggt tgatgatggt
      301 taagaaacat tattttaaag ataatgaaga agactctaaa atgcgtagga ttttgcttct
      361 agttgctgtt ttgctgatga ttccgagttt tatttctgca acgactttag tgagagaaac
      421 gttgaaaaaa gagtccctta agaaatttat atcagagcag tttcaggggt ataatatttt
      481 gaaaaaaacc tattctaaaa agactcatac cctaaagcta accatttcag gaaattattt
      541 gacagaagaa gaactcgata tgatttcaag taagagaggt gactatggtt taagtgatgt
      601 ttctgttcaa gtttcacaat tgtctgattc agaacaactt agtaaggaag agctggtgga
      661 gtatttcttc cagtatatca aggataagga agcaaaagaa aaggagaagg ccaataaatt
      721 tgatacagag tctgaggagc aataatttct tgagaatagc tggtttctct cgtgagtctt
      781 ctatgtatat caaaggaaga ctgaggtttt aagtataaaa cttttcttct attatagtag
      841 ctaagtcttg acagggttca aaaaatggtt tacactttat aaagtttatt actttgaaaa
      901 ggtgtgatac tgtggctacg gcaacaaaaa agaaaaaatc aacagttaaa aaaaatctag
      961 tcatcgtgga gtcgcctgct aaggccaaga cgattgaaaa atatctaggc agaaactaca
     1021 aggttttagc cagtgttggg catatccgtg atttgaagaa atccagtatg tccgtcgata
     1081 ttgaaaataa ttatgaaccg caatatatta atatccgagg aaaaggccct cttatcaatg
     1141 acttgaaaaa agaagctaaa aaagctaata aagtttttct cgcgagtgac ccggaccgtg
     1201 aaggagaagc gatttcttgg catttggccc atattctcaa cttggatgaa aatgatgcca
     1261 accgtgtggt cttcaatgaa atcaccaagg atgcagtcaa aaatgctttt aaagaacctc
     1321 gtaagatcga tatggacttg gtcgatgccc aacaagctcg tcggatcttg gaccgcttgg
     1381 tagggtattc gatttcgcct attttgtgga agaaggtcaa gaagggcttg tcagcaggtc
     1441 gcgttcagtc cattgccctt aaactcatca ttgaccgtga aaatgaaatc aatgccttcc
     1501 agccagaaga atactggaca gttgatgctg tctttaaaaa gggaaccaaa caatttcatg
     1561 cttccttcta tggagtagat ggtaaaaaga tgaaactgac cagcaatgac gaagtcaagg
     1621 aagtcttgtc tcgtctgacg agtaaagact tttcagtaga tcaggtggat aagaaagagc
     1681 gcaagcgcaa tgctccttta ccctatacca cttcatctat gcagatggat gctgccaata
     1741 aaatcaattt ccgtactcga aaaaccatga tggttgccca acagctctat gaaggaatta
     1801 atatcggttc tggtgttcaa ggtttgatta cctatatgcg taccgattcg actcgtatca
     1861 gtcctgtagc gcaaaatgag gcggcaagct tcattacgga tcgttttggt agtaagtatt
     1921 ctaagcacgg tagcaaggtc aaaaacgcat caggtgctca ggatgcccat gaggctattc
     1981 gtccgtcaag tgtctttaat acaccagaaa gcatcgctaa gtatctggac aaggatcagc
     2041 tcaagctata tacccttatc tggaatcgtt ttgtggctag ccagatgaca gcggccgttt
     2101 ttgataccat ggctgttaaa ttgtctcaaa aaggggttca atttgctgcc aatggtagtc
     2161 aggttaagtt tgatggttat cttgccattt ataatgattc tgacaagaat aagatgttac
     2221 cggacatggt tgttggaaat gtggtcaaac aggtcaatag caaaccagag caacatttca
     2281 cccaaccgcc tgcccgttat tctgaagcaa cactgattaa aaccttggag gaaaatgggg
     2341 ttggacgtcc atcaacctac gcgccaacca ttgaaaccat tcagaaacgt tattatgttc
     2401 gcctggcagc caaacgtttt gaaccgacag agttgggaga aattgtcaat aagctcatcg
     2461 ttgaatattt cccagatatc gtaaacgtga ccttcacagc tgaaatggaa ggtaaactgg
     2521 atgatgtcga agttggaaaa gagcagtggc gacgggtcat tgatgccttt tacaaaccat
     2581 tctctaaaga agttgccaag gctgaagaag aaatggaaaa aatccagatt aaggatgaac
     2641 cagctggatt tgactgtgaa gtgtgtggca gtccaatggt cattaaactt ggtcgttttg
     2701 gtaaattcta cgcttgtagc aatttcccag attgccgtca tacccaagca atcgtgaaag
     2761 agattggtgt tgagtgtcca agctgtcatc agggacaaat tattgagcga aaaaccaagc
     2821 gtaatcgcct attctatggt tgcaatcgct atccagaatg tgaatttacc tcttgggaca
     2881 agcctgttgg tcgtgactgt ccaaaatgtg gcaacttcct catggagaaa aaagtccgtg
     2941 gtggtggcaa gcaggttgtt tgtagcaaag gcgactacga ggaagaaaag attaaataag
     3001 aggaggggcc cgaaagtaaa tttcaggctc cttttggtta gaacttgaca aaatacatca
     3061 ttttatgcga aactagaaga agattatttt aactaggaga agttatgcgt cttatctatc
     3121 tgataattgg ttttttatca ctggccttgg ctattgttgg ggttgtttta cccttgttgc
     3181 cgacaacgcc tttccttttg ttgtctattg cttgtttctc cagaagttcc aagcgtttcg
     3241 aagactggct ttatcatacc aagctctatc aaacatatgt agctgatttt cgcgagacta
     3301 agtctattac gcgtgaacga aagaaaaaaa tcatcgtctc tatctacgtc ttgatgggaa
     3361 tttctattta ttttgcacct cttttaccag tcaaaatcgg tctgggtgct ttgaccatct
     3421 ttatcactta ttatctcttc aaggtcattc cagacaaaga atagttaaaa cagtagttat
     3481 ttgccttgat aaaattgaaa gcatattcat aacaatatga tataataaat ttgaagtaat
     3541 attcaaggag aatcaaatga tttacgaatt ttgtgctgaa aatgtgactt tacttgaaaa
     3601 agcgatgcag gctggagctc gtcggattga actctgtgat aatctagcag ttggtgggac
     3661 aacacccagc tatggagtga ctaaggcagc ggttgaactg gcagctaact acgatacaac
     3721 catcatgacc atgattcggc cacgtggtgg tgactttgtc tataatgacc tagaaattgc
     3781 tatcatgcta gaagacattc gtttgactgc tcaggctgga agtcaagggg ttgtatttgg
     3841 aactttaact gctgataaaa agttggataa gcctaatctg gaaaagttaa ttgctgcatc
     3901 aaaaggaatg gaaattgtct ttcacatggc ctttgatgaa ctaagtgatg aagatcaact
     3961 ggaagctatt gactggctca gtcaagccgg tgtcactcgt atcctaactc gtgctggtgt
     4021 gtctggcgac tccttagaaa aacgttttgt tcactatcac agaattttgg agtacgctaa
     4081 aggtaaaatt gaaattctac caggtggggg gattgacctt gaaaaccgtc aaacctttat
     4141 tgaccaggtg ggggtaacac aattgcatgg tactaaggtt gttttttaaa aaatagaaag
     4201 gaactgctag ccttgggtag cagttttcac ttatgtttga aatttttaaa tcctatcaat
     4261 ttaatcaaga aaaggctcat gattatggtt ttatagaaaa tagcgaagtc tggacatata
     4321 gttgccagat tttgcaaggt gactttgtca tgactgtgtc catcactgct gataatgtga
     4381 actttcaagt ctttgaccaa gagactggtg acctctatcc tcacgttcat atggaaagca
     4441 tgaggggaag ttttgtcgga aatgtccgtg aggcttgtct ggagattctt taccagattc
     4501 ggaaggcttg ttttgatgtg caagatttta tctgtcatca gactaagcgt atcatgactc
     4561 aagttcagga aaagtatgga aaccagttgg agtatctgtg ggaaaaatcg cctgatacag
     4621 ctgtattgcg ccatgaaggc aatcaaaagt ggtatgccgt cttgatgaaa atctcttgga
     4681 ataagctgga aaagggcaga gaaggacaag tggaagcagt caacctcaag catgaccaag
     4741 tagctaattt gctttcacaa aaggggattt atccagcctt ccatatgagc aagcgctact
     4801 ggattagtgt gtcccttgat gatactttat cagatgaaga agtactggaa ttgatagaaa
     4861 aaagttggaa cttaacctct aaaaaatgaa atattttaat aattttcatg aactttcaat
     4921 tagctgaata ttctttactg aagaaatttt cagaaaatat aggatttacc acaccagagg
     4981 aatgtggtgc catcttcaaa tacctgattg agaatgtcaa gacggatcgt cagatcatct
     5041 attcgcctca ctgtcatgat gacctcggaa tggcagtggc aaatagcctt gctgctgtca
     5101 agaatggtgc aggacgtgtt gaagggacta tcaatggtat tagggagcga gctgaaaatg
     5161 ctgctttgga agaaattgca gtggctctca atattcgcca agattactac caagtagaaa
     5221 ccagtattgt cctaaatgag accatcaata cgtcagaaat ggtttctcgc ttctctggta
     5281 ttccagttcc taaaaacaaa gccgtcgttg gtggcaatac cttctcccac gaatctggta
     5341 ttcaccaaga tggagtcctt aaaaatcctc tcacttatga gatcatcaca cctgaattgg
     5401 ttggtgttaa gattccgctt ggaaaattat ctggtcgcca tgcttttgtt gagaaactga
     5461 gagaattggc cctagatttt acagaagagg atatcaaacc actctttgct aagttcaagg
     5521 cactggccga taagaagtaa gaaatcacag atgcagatac tcgagctttg gtagctggaa
     5581 ccatggttga aaatccagaa ggcttccact ttgatgattt acaacttcaa actcatgcag
     5641 ataatgacat tgaagcgctc gttagcctag ccaatatgga tggtgagaaa gtcgaattta
     5701 atgcgacagg gcaaggttcc gttgaagcaa tctttaatgc tatcgataag ttctttaacc
     5761 aatctgttcg tttggtgtcc tacactatcg atgcggtaac agatggaatc gatacccagg
     5821 atcgggtttt ggtcactgtt gaaaacagag atacagaaac catctttaat gcagcagggc
     5881 ttgattttga tgtgttgaag gcttctgcta ttgtctatat aaacgctaat acctttgttc
     5941 aaaaagagaa tgcaggtgag atgggacgca gtgtttctta ccacgatatg cctagtgtgt
     6001 aaaggagaag gctatggcaa agaaaatagt agctctagca ggagacggaa ttggcccaga
     6061 aatcatggag gttggtttag aagttctgga ggctctagct gaaaaaacag gttttgacta
     6121 tgagattgac agacgaccgt tcggaggtgc agatattgat gcagcaggac ctcccttacc
     6181 tgatgaaacc cttaaggcaa gtagggaagc agatgctatc ctactagcag ctatcggtag
     6241 tcctcagtat gatggagcag tggttcgccc tgaacagggc ctgatggctc tccgtaagga
     6301 actcaatctt tacgctaata ttcgtcctgt aaaaatcttt gacagtctca agcatttgtc
     6361 accactcaaa ctggaacgaa ttgctggtgt agactttgtc gtggtgcgtg aattgacagg
     6421 cgggatttac tttggagatc atattcttga agagcgcaat gcgcgtgata tcaacgacta
     6481 tagctatgag gaagtggagc ggattattcg caaagccttt gaaattgcaa gaaatcgcag
     6541 aaaaatcctt actagtatcg ataagcaaaa tgttctagcg acctcaaaac tatggcggaa
     6601 agtagctgag gaagtcgcac aggatttccc agatgtaacc ttggaacacc agctggtaga
     6661 ctcagctgct atgcttatga ttaccaatcc tgctaagttt gatgttattg taacggagaa
     6721 tctttttgga gatattttat ctgatgaatc aagcgtctta tctggtacac ttgaggttat
     6781 gccatcagcc agtcattctg aaaatggacc aagtctctat gaacctattc acggttcagc
     6841 acctgatatt gcaggtcaag gaattgccaa tcctacttcc atgattttat cagttgccat
     6901 gatgttgaga gatagtttcg gacgttatga ggatgcagag cgtatcaaac gtgctgttga
     6961 gacaagtctg gcggcaggaa ttttaacgag agatatagga ggtcaggctt caacaaagga
     7021 aatgacggaa gctattattg caaggttatg aagttagacg aaaaaattac tctagtcctt
     7081 ttgatttgga atgtcatcat tttcttgatt tatggcattg acaaattcaa ggcaagaaga
     7141 agagcttggc gcatcccaga gaaaatctta ctcattttag cccttacttg tggtggtttt
     7201 ggggcctggt tagctggaat tacttttcac cacaagactc gaaaatggta ctttaaaaca
     7261 gtttggtttc ttgggatggt gaccacacta gtagccttat attttatttg gaggtaatgg
     7321 atggcagggt cttcgaggga acacgctgct tgggctctag cggactatgg ttttaaggtc
     7381 gtgattgcag gatctttcgg tgacattcat tacaataatg aactcaataa tggcctgttg
     7441 ccaatcgttc agcctagaga ggttagagag aaattagccc agctaaaacc aaccgaccag
     7501 gtaactgtgg acttggaaca acaaaaaatc atctcaccag ttgaagaatt caccttcgag
     7561 atagatagcg agtggaaaca taaactccta aatagtttgg atgatatcgg tattaccttg
     7621 cagtatgaag agttgattgc tgcttatgaa aaacaacgac cagcctactg gcaggattag
     7681 aaaaaataga aaaggaaata tagtaaactg aaataagatg taaacaaatg aattagagct
     7741 taacatccat ttccagcaat tttttagaaa ctacagtgga ctattctgga ttcaacacat
     7801 tataaaatta tgacaaaaca cattcacaag aaggctacga cattttaaaa ggtgagggcg
     7861 gatgtatcgt ttgccctact aaagttggtt acattatcat gaccagcaac aaggcaggac
     7921 ttgagcgtaa gttcgcagcc aaagaacgta agcgtaacaa accaggtgtt gttctctgcg
     7981 gtagcatgga tgaactttgc gctttagcgc aactcaaccc agaaattgaa gcattctact
     8041 aaaaacattg ggatgaagat attcttcttg gttgtatcct tccttggaaa ccagaagcct
     8101 ttgaaaaact caaagcatac ggggatggcc gtgaagaact tatgactgat gtacgtggta
     8161 ctagctgttt tgttatcaag tttggaaaag caggtgaaca attggctgcc aagctttggg
     8221 aagaaggtaa aatggtctac gcctcatatg cttcaatgac aaaacgattg aaactcgcta
     8281 tgagagcaag gtgtaatggt gtctatggtc gataaggacg gcaaactcat cccagaacaa
     8341 ggaggagcac gttcaacctc accagcacca gttgtgatcc gtaaagggct tgacattgat
     8401 aaaatcatga tgcacctgtc agatactttt aactcatggg actaccgtca ggttgagtat
     8461 tattaggata gagaagaagt ctagtgttaa ggacattaca gctcataata ctaggctttt
     8521 ttatagaaat tcttttcttt ttctatagga tatggtattc tatgtagaaa atatatgtta
     8581 ataagtaatg ccaatattta aacatcatta gtaaaaggag ttagattgat gaataaaaga
     8641 aaagttagtt tagaagattt ttataaatgg tatagtctaa ataaagaaga gttattaaat
     8701 aaggcaactg ttggtgaaaa gtttaatgat aaattaaaag aagagtttct ccaggaatgg
     8761 cctttggata ggattttaac aatgtcaatc gatgaatatg taataggaaa gggacagcaa
     8821 aataagtctt tatgctacgc tcttgagaag ggaaaataca aaaatctatt tcttggaatt
     8881 tctggtggct cagcttcaaa atttggtatt tattggaata aaaaaacaaa caaatataaa
     8941 gatcaagcta ataatgagat ttcagagttg gatcagcgat tttcaaaatt aaaatcagat
     9001 ttgtatgaaa ttatcaaaga aggtattcgt tttaactttg aaaatcctat ttttgatatg
     9061 aaaagatcaa caaatgaatt tattggtcgt tctgctatgg tgacaaaatt actttgtatc
     9121 tattctgagg gagatccttt ctttggtgta aatattaata gtcagaaaga attttggaac
     9181 cactttgttt ctcagacaaa tcaaggtgga ccttatctgc aaaatcataa aataattgaa
     9241 ctggtgtcca aaacttatcc tgagttggag ccatcgaaag taggaactat gctttttgag
     9301 tattctaagc tttttatgga aaataaggaa gacaatagta caatggattc atcaaacaat
     9361 tttcgtcatc aattaactca atctctatta aagtctccaa accttatcct tcgtggtgct
     9421 cctggcacag gaaagactta tcttgctaaa gaaattgcca aagaattaac ggatggcaac
     9481 gaagaccaaa tcggatttgt acaatttcac ccatcatatg attatacgga ttttgtagaa
     9541 ggtttaagac cagtatcaaa tggggatgga gctattgagt ttaggctaca ggacggtatt
     9601 tttaaagatt tttgtcagaa agcaaaagaa acccaattga ttggaggaca agataatttt
     9661 gatgaggctt gggattctta cttagaatat ataaatgttg ctgaagaaaa agaatatata
     9721 acaaaaacat cttacttatc tgttaatagt agacaaaatt tgtcagtaaa ttatgatagt
     9781 ggtgttccag gatggtcact acctagcaaa tatgtttacg agttgtataa agataaaaat
     9841 tataataagc aagaatacta caaaagtggt ggaaaaactg tcctagaaac attgagaaag
     9901 agatttggtt tgaaagacta tgtttcccca acagaaattg atactgataa gaaattcgtc
     9961 ttcatcatcg atgaaatcaa tcgtggggag atttctaaga tttttggcga actctttttc
    10021 tctatcgacc ctggctatcg tggtgaaaaa ggaagtgttt ctacccaata tgcaaatcta
    10081 cacgaaactg atgaaaagtt ctatatcccc gaaaatgttt acatcatcgg aactatgaat
    10141 gatattgatc gttcagtgga tacctttgat tttgctatgc gtcgtcgttt tcgttttgtt
    10201 gaagttactg ccgagggtca agttggcatg ttgggtaaag agctgaatat ccatgcagaa
    10261 gaagcaaaaa ttcgtctaag aaacttgaac gctgctatcg aaaatgttca ggaattaaac
    10321 agtcattatc atattggacc aagttatttt cttaagttga aggatgtaga ttttgactat
    10381 gaattactct ggtctgatta tattaagcct ctcctagaag actacttgcg aggttcttat
    10441 gatgaggttg aaactttgga aactttgaaa aaagcatttg aactgacaaa taatgagcaa
    10501 aaagatcagg cagtagctga tgacaatgaa ggtgatgaaa acgatgatgc ggattactga
    10561 taatcaacac aagattatta aagaaaaatt tgttgaagaa tatcctaaac taagcaatct
    10621 tcttttagac agaaccttgg aaagtctatc ccaagatgaa cgtattttca tttttccaaa
    10681 tgatttgact catactcctg atttggataa ggaccaaaag atttttgaaa cagtcaatca
    10741 gaaaatcaag acagggaacg tgattggttt tcttggatat ggtcaggaaa gattaacgat
    10801 ttcctcacga ttttctgatg agagtaatga ccattttttg cattatctct taaacaaggt
    10861 tcttcatatc aatctcacta gtttagatgt tgctttgtct cgtgaagaga ggctttatca
    10921 acttttggtg tatctctttc ccaagtatct acaagctgct attcgaaaag gtctttataa
    10981 ggaatatcat cgattttctc ataacgacag tcatgttaag ggagtgattg atgtaagaag
    11041 ccatctcaag aaaaatcttc ctttcacggg aaatattgcc tacgcaacga gagagttcac
    11101 ctatgataat cccctcatgc agttggtccg tcacactatt gaatacatta agaatcagaa
    11161 aagcattggt caaggggtac tagataatct ctcaactagt cgtgaaaacg tatctgaaat
    11221 cgtgcgtgta acgccctctt ataaactagc tgatcgtgct aagattattc ggggaaatca
    11281 atctaaacct atacgtcatg catactttca cgagtacaga aacttacaag aactttgtct
    11341 gatgatccta aaccaagaaa agcacggttt agggtatcaa gatcaaaaaa tctatggtat
    11401 tctctttgat gttgcctggc tttgggaaga gtatgtttac accttgttgc caaaaggttt
    11461 tgtacatccc agaaataagg ataagacgga tggaatttca gtattttctg ttgggaaacg
    11521 aaaagtatat ccagattttt atgacagaga acgaaagatt gttctagatg caaaatataa
    11581 aaaactggaa ttgactgaaa aaggaatcaa ccgtgaggac ttattccagc tgatttccta
    11641 ttcttatatt ttaaaagctg agaaggctgg actgattttt cctagtatgg agcagtcagt
    11701 aaatagtgaa ataggaaaag tagctggcta tggagctcaa ttgaagaagt ggtctattcg
    11761 aatccctcag aatgcctcat tctatagtac attttgtaaa atgatggaaa attcagaaga
    11821 aaattttaaa gcgattattg atgaagaagt ggggagaaaa taatttcccc tctttctttt
    11881 atttttaaca caagtaaaac ccgaacgata tattttaatt cataaaataa tttgacaaaa
    11941 actgtacttt ggtttataat aaattaagga aacgtcggaa aaggcgtagt gatgcaagag
    12001 cataggtagg tcattacaaa agaaacgaga catcgatatg ttaaatgaat ttccaatttt
    12061 tgattacgaa gatattcaat tgattccaaa taaatgtgtc attaaaagcc gtgcagaagc
    12121 ggatacaagt gtcactttag gaaatcacac ctttaaacta cctgttgtgc cagcgaatat
    12181 gcagacgatt ttggatgaaa atgtagcaga gcaactggct aaaggtggtt acttctacat
    12241 tatgcaccgt tttgatgagg caggacgcat tccttttatt aaacgaatgc acgatcaagg
    12301 gctcattgct tctatctctg tcggtgttaa ggattatgag tatgattttg ttagccagct
    12361 caaggctgat gctcctgagt atatcactat tgatattgct catggtcatg cggatagcgt
    12421 gatttctatg attcaacaca tcaagaaaga attgccagat acctttgtca ttgctggaaa
    12481 tgtgggaaca ccagaagctg tgcgtgaatt ggaaaatgct ggtgcggatg ctactaaggt
    12541 cggaatcggt cctggtaagg tttgtatcac caaggttaag actggttttg gtacaggtgg
    12601 ttggcagttg gctgctctac gctggtgtgc caaggctgcg cgtaaaccga ttatcgctga
    12661 tggaggaatt cgtactcacg gtgatattgc taagtctatc cgcttcggtg ctagcatgat
    12721 catgattggt tccctctttg caggacacat tgaaagtcca gggaaaacga ttgaagtcga
    12781 tggtgaacag ttcaaagaat attatggttc agcctcacaa tatcaaaaag gtgcttacaa
    12841 aaatgtggaa ggcaaacgta tcttgcttcc tgctaaaggt catctgcaag acactttaac
    12901 tgagatggaa caagaccttc aaagtgctat ttcttatgca ggtggacgtc aggttgctga
    12961 ccttaaacac gttgattatg tgatcgtgaa aaactccatc tggaatgggg atgcttccca
    13021 ctaagacggg gtctttgacc aaaaaacttg ttattagagc aaatttctgt tataataaaa
    13081 caagtttcca cccttagtgt aatggatatc acgtaagatt ccggttcttg agatgggggt
    13141 tcgattccct cagggtggat gtaaacatcc taaaaagcct ttaatagggc ttttttcttt
    13201 atcctgaccc aaatttgccg ctaaaactga gaatctctgt ctaaagaatt cccaaatgct
    13261 ttccagtccc gttttagagt gactcagggg gctttttttg atataataaa aaggactatt
    13321 atcagttaga aagaggttgg tatgaaagaa ttacaaactg tactaaagaa ccattttgca
    13381 atcgaattta cagacaaaaa gttactggaa actgccttta ctcatacgag ttatgccaat
    13441 gagcaccgcc tcttaaaaat ttcacacaat gaacgcttgg aatttttagg agacgctgtt
    13501 ctacagttat tgatttcaga atatctatat aaaaaatatc ctaaaaagcc tgaaggtgac
    13561 ctatcaaaac tccgtgctat gattgtccgt gaggagagtt tagctggttt tgcgcgtgat
    13621 tgccagtttg accagtttat caagttgggt aaaggggaag aaaaatctgg tggtcgcaat
    13681 cgtgacacca ttcttggtga tgcctttgaa gcctttcttg gtgcccttct tttggataag
    13741 gatgtggcca aggtcaagga atttatctat caagtcatga ttcctaaggt tgaagcaggc
    13801 gagtttgaga tgattacaga ctataaaacc catctccaag agttgcttca ggtcaatggt
    13861 gatgtggcta ttcgttatca ggtgatttct gaaacagggc ctgctcacga taaggtcttt
    13921 gatgtagaag ttcttgttga aggtaagagc atcggtcaag gccaaggtcg ttctaagaaa
    13981 ttagcagagc aggaagctgc caaaaatgcc gttgagaagg ggctggattc atgtatttaa
    14041 aggaaatcga aattcagggg ttcaagtctt ttgctgataa gaccaaggtc gtttttgacc
    14101 aaggtgtgac ggcagttgtt ggacccaatg gatctggaaa gtccaatatt acagaaagtc
    14161 tgcgttgggc tttgggggag tctagtgtca agagtctccg tgggggcaag atgccggatg
    14221 tcatctttgc tggaaccgaa agtcgcaaac cgctcaatta tgcttctgta gttgtgactc
    14281 tggataatca tgacggattt atcaaggatg caggtcaaga aatcagggtg gaacgccata
    14341 tctatcgtag tggagatagc gaatacaaga ttgacggcaa gaaagtccgt ctgcgtgata
    14401 ttcatgacct cttcttggat actggattgg gacgagattc cttctctatt atttcccaag
    14461 ggaaggttga ggagattttt aattccaagc ctgaggaacg acgatctatt tttgaagaag
    14521 ctgctggagt tttaaaatac aagactcgca gaaaagaaac cgagagtaaa ctgcagcaaa
    14581 ctcaggataa tctggaccgc ttagaggaca ttatctacga gttggataat caaatcaagc
    14641 ctcttgagaa gcaagctgag aatgcccgta agtttttaga cttggaagga caacgtaagg
    14701 ctatttattt agacgttctg gttgctcaaa tcaaggaaaa taaggctgaa ctagagtcga
    14761 cagaagaaga gttggctcag gttcaagaac tcttgatgag ttattaccaa aagcgtgaaa
    14821 aattagaaga agaaaatcaa actcttaaaa agcaacgcca agatttacag gctgaaatgg
    14881 ccaaagacca aggcagtttg atggacttga ctagtctgat tagtgattta gaaagaaaat
    14941 tagccctatc gaaactggag tccgagcaag tggccttgaa tcaacaggag gtacaagctc
    15001 gtttggctgc tttggaggat aagagaaatt cactcagcaa agaaaagtct gataaagaaa
    15061 gctctttagc tctgttagag ggaaatctag tccaaaataa tcaaaaactc aatcgtttag
    15121 aagctgaatt gctggctttc tcagacgatc ctgatcagat gattgagctc ttacgtgaac
    15181 gctttgtagc tcttttacaa gaagaagcgg atgtctcaaa ccagttgacc cgtattgaga
    15241 atgagttgga aaatagtcgt cagctttctc aaaaacaagc agatcaacta gaaaagctga
    15301 aagagcaatt ggctatagct aaagagaagg ctagtcagca aaaggaagag cttgaaactg
    15361 ccaaggagca ggttcagaaa ttattggctg actaccaagc tattgccaag gagcaagagg
    15421 agcagaaaac ttcctatcaa gctcaacaaa gccaactctt tgaccgtctg gataatctca
    15481 aaaacaagca ggccagagct caaagtttgg aaaatatcct gagaaatcat agtaactttt
    15541 atgcaggtgt taagagtgtt ctccaagaaa aagatcgcct aggtgggatt attggtgcag
    15601 tcagtgagca tctgaccttt gatatgcatt atcaaactgc cctagaaatt gcacttggag
    15661 cgagtagtca gcacattatt gtagaagatg agaatgcggc aaccaaagcc attgatttcc
    15721 tcaaacgaaa cagagccggt cgtgcaacct ttcttccttt gaccactatt aaggcgcgta
    15781 cgatttctag tcagaaccaa gatgctatcg ctgtaagccc aggtttcctt gggatggcag
    15841 atgagttagt tactttcgat actagactgg aagccatttt caagaacttg ctagctacga
    15901 cggctatctt tgataccgta gaacatgcgc gtgaagctgc tcgacaagtt cgttatcagg
    15961 ttcgcatggt gacattggat gggacagagc ttcgtacagg tggttcctat gcaggtggag
    16021 ccaatcgtca gaacaacagc atcttcatca agccagaact ggagcaatta caaaaagaaa
    16081 ttgctgaaga agaagcaagc ttggattcag aagaagtggc tttgaagacc ttgcaagatg
    16141 agatggccag attgatcgag tcattagaag ctattaaatc tcaaggagag caggcacgta
    16201 ttcaggagca aggcttgttc ctcgcttatc agcaaactag tcagcaagtt gaagagctag
    16261 aaactctttg gaaactccaa gaaaaggaat taaatcgtct ttctgatgga gattggcaag
    16321 cagacaagga aaaatgccaa gaacgccttg ctactatcgc cagtgacaag caaaatctgg
    16381 aagctgagat tgaagagatt aagtctaaca aaaatgccat ccaagaacgc tatcaaaact
    16441 tgcaggaaga gctagcgcaa gctcgtttgc ttaagacaga actgcaaggg caaaaacgtt
    16501 atgaagttgc tgatattgaa cgcttaggca aggaattgga caatcttaat atcgaacaag
    16561 aagaaatcca gcgcatgctc caagaaaaag ttgacaatct tgagaaggtt gatacagaat
    16621 tgctcagtca acaggcggaa gaatccaaaa ctcagaaaac aaatctccaa caaggtttga
    16681 ttcgcaagca gtttgagttg gatgatatag aaggtcaact ggatgatatt gccagtcact
    16741 tggatcaagc tcgccagcag aatgaggagt ggattcgcaa gcaaacacgt gctgaagcca
    16801 agaaagaaaa ggtcagcgag cgcttgcgcc atctacaaag tcaattaaca gaccagtacc
    16861 agattagcta tactgaagct ctagaaaaag cgcatgaatt ggaaaacctc aatctggcag
    16921 agcaagaagt taaggattta gagaaggcta ttcgctcact gggtcctgtc aatatagaag
    16981 ctattgacca gtacgaagaa gttcacaacc gtctggactt tctaaatagt cagcgagatg
    17041 atattttgtc agcgaaaaat ctgctccttg aaaccattac agagatgaat gatgaggtca
    17101 aggaacgctt taaatcaacc tttgaagcta ttcgtgagtc ctttaaagtg accttcaagc
    17161 agatgtttgg cggaggtcag gcagacttga tattgactga gggcgacctt ttaacagctg
    17221 gtgtggagat ttctgttcaa cctccaggta agaaaatcca gtcgcttaac ctcatgagtg
    17281 gtggtgaaaa agctctatcg gctcttgcct tgcttttctc cattattcgt gtcaagacca
    17341 ttccttttgt catcttggat gaggtagagg ctgcgctaga cgaagccaat gttaaacgtt
    17401 tcggggatta tctcaaccgc tttgataagg acagtcaatt tattgtcgta acccaccgta
    17461 aggggaccat ggcagcggcc gattctatct atggagtgac catgcaagaa tcgggtgttt
    17521 caaagattgt ttcagttaag ttaaaagatt tagaaagtat tgaaggatga caattaaact
    17581 agtagcaacg gatatggacg gaaccttcct agatgggaat ggacgctttg atatggatcg
    17641 tctcaagtct ctcttggctt cctacaagga aaaagggatt tactttgcgg tggcttcggg
    17701 tcggggattt ctgtctctgg aaaaattatt tgctggtgtt cgtgatgaca ttattttcat
    17761 cgcggaaaat ggcagtttgg tagagtatca aggtcaggac ttgtatgaag cgactatgtc
    17821 tcgtgacttt tatctggcaa cttttgaaaa gctgaaaacg tcaccttatg tagatatcaa
    17881 taaactgctc ttgacgggta agaagggttc atatgttcta gatacggttg atgagaccta
    17941 tttgaaagtg agtcagcatt ataatgaaaa tatccaaaaa gtagcgagtt tggaagatat
    18001 cacagatgac attttcaaat ttacaaccaa cttcacagaa gaaacgctgg aagctggtga
    18061 agcttgggtc aatgataatg tccctggtgt caaggctatg acaactggct ttgaatctat
    18121 tgatattgtt ctggactatg tcgataaggg tgtagctatt gttgaattag ctaaaaaact
    18181 tggtatcaca atggatcagg tcatggcttt tggagacaat cttaatgact tacatatgat
    18241 gcaggttgtg ggacatcctg tagctcctga aaatgcacga cctgaaattt tagaattagc
    18301 aaagactgtg attggtcacc ataaggaacg gtcggttata gcttatatgg agggcttata
    18361 atggcagata taaaattgat tgcattggac ttggacggga ccttgctgac tactgataaa
    18421 aggctgacgg atcgtaccaa ggaaaccttg aaagctgcgc gtgatcgtgg tatcaaggtc
    18481 gtattgacaa ctggtcgtcc cttaaaagcc atggatttct ttctccatga gttagggact
    18541 gacggtcagg aagatgagta taccattact tttaatggtg gattagttca gaaaaataca
    18601 ggagaaatcc ttgataaaac agtcttttca tatgatgatg tggcacgttt gtatgaagaa
    18661 acagagaaat tatcactgcc tcttgatgcc atctcagaag gaacagttta tcaaatccaa
    18721 tcggaccaag aaagtcttta tgccaaattc aatccagctt tgacctttgt tccagtggac
    18781 tttgaagact tatctagtca aatgacctac aacaaatgcg tgactgcctt tgctcaagaa
    18841 cccttggatg cagccattca gaagatttct ccagaattgt ttgaccaata tgaaatcttt
    18901 aaatcacgtg aaatgttgct agaatggtca ccaaagaatg ttcataaagc aacaggtttg
    18961 gcaaaactaa tcagccatct tggaatcgac caaagtcaag tgatggcttg tggtgacgag
    19021 gccaatgacc tctctatgat tgaatgggca ggtcttggtg ttgctatgca aaacgctgtt
    19081 cctgaagtaa aggcagccgc aaatgtagtg acgccgatga ccaacgatga ggaagctgtc
    19141 gcctgggcta tcgaagaata tgtgctaaag gagaactaag atatgggatt gtttgaccgt
    19201 ctattcggaa aaaaagaaga acctaaaatc gaagaagttg taaaagaagc tctggaaaat
    19261 cttgatttgt ctgaagatgt taatcctacc ttcacagaag ttgaggaagt ttctcaggaa
    19321 gaagcagagg ttgaaattgt tgaacaagct gtgttccaag aagaggaaat ccaagacaca
    19381 gttgaagaaa gtctggattt agagccagtt atagaagttt ctcaaaaaga agtcaaagaa
    19441 tttccacact cagaagaagg gaatactgag tttctagaga ctgtagaaga aaataattct
    19501 gaaattcttg aagcagaaag gcctcaaaca gaagaaactg ttcaggaaaa atatgaccgc
    19561 agtcttaaga aaactcgcac aggtttcggt gcccgcttga atgccttctt tgctaacttc
    19621 cgctctgttg acgaagaatt tttcgaggaa ctggaagaac tgttgattat gagtgatgtt
    19681 ggtgtccaag tcgcttctaa cttaacggag gaactacgtt acgaagccaa gcttgaaaat
    19741 gccaagaaac ctgatgcact tcgtcgtgtc atcattgaga aattggttga gctttatgaa
    19801 aaggatggta gctacgatga aagcatccac ttccaagata acttgacagt tatgctcttt
    19861 gttggtgtga atggtgttgg gaaaacaact tctatcggaa aactagctca ccgctacaaa
    19921 cgagctggta agaaggtcat gctggttgca gcagatacct tccgtgcggg tgcagtagct
    19981 cagctagctg aatggggccg acgagtagat gttccagtag taactggacc tgaaaaagct
    20041 gatccagcca gcgtggtctt tgatggtatg gaacgtgccg tggctgaagg tatcgatatt
    20101 ctcatgattg atactgctgg tcgtctgcaa aataaggata accttatggc tgagttggaa
    20161 aagattggtc gtattatcaa acgtgttgtg ccagaagcac cacatgaaac cttcttggcg
    20221 cttgatgcat caacaggtca aaatgcccta gtacaggcca aagaattttc gaaaatcaca
    20281 cctttaacgg gaattgtttt gactaagatt gatggaactg ctcgaggagg tgtggttcta
    20341 gccattcgtg aagaactcaa tattcctgta aaattgattg gttttggtga aaaaatcgat
    20401 gatattggag agtttaactc agaaaacttt atgaaaggtc tcttggaagg cttaatctaa
    20461 tcagaagcaa aaatcctgca aggtacaaac ttgcaggatt tttttattct aagcgaccat
    20521 cttgacgata ggcgatatct ggttgccaag tccatttggc accgaatttt tcaagtaggt
    20581 caaagctggc ttgaggtccc atgcttccag ctttatagtc atgaagtggg acaccatttt
    20641 cagcccagag cttttcaata cgatcaatca acttccatga cgcaccaact tcatcccagt
    20701 ggctaaagtt agttgagttg ttatttagga catcataaat caatttttcg tatggttctg
    20761 gagaagcacc agttgcagtc gcgtctgtac gataatcaag tgagttagga gccaagttaa
    20821 attcttctcc tacttgcttc ccatttaggc taagagagaa gccttctgtt ggttgaatat
    20881 agatggtcaa aatatttgga gcaagtggtt ctccaaagat agaatccatt tgtttaaaga
    20941 cgatgttgac atgagttcct ttttcagtca gtcgtttacc tgtacggaaa aagaaaggaa
    21001 cactacggaa tcgatcgctg tctacaaaga aggcaccaga tgtaaaggtt tcagttgttg
    21061 attctggatt cacatttggc tcgctacgat aagagatgta tttcatgcca tcaatcttac
    21121 cagagcggta ttgcccacgg ataaagtgtt ctttgagttc ttcatcagtt ggatgataga
    21181 ggtttttaaa gaccttaatc ttttcagcac gaatctcgtc ttttgtgaag cttgctggtt
    21241 tgtccatggc gagaagcgaa agaagttgta gagtgtggtt ttggaccatg tcacggaggg
    21301 caccggattg gtcatagtag ccaccacgtt cttctacacc caagcgctcc gcaaaggtaa
    21361 tttgaacatt gtcgataaaa tccttgttcc aaacgttttc aaaaatcaag tttgcaaagc
    21421 gaactgcaaa gatgctttgg atcatttcct taccaagata atggtcgata cggaaaattt
    21481 gttcttcgtc aaatgttgct aggagttcgt cattcaactt gcttgcagtt gcgtaatctg
    21541 taccaaatgg tttttcaacg atcaagcgct caaaaccttt gtcatcgaca atgttttcag
    21601 atttgaggtg tttggcaatg gttccaaaga actgaggtgc catagacaag aagaagagct
    21661 tattgtgttc agcttggtat ttttcattaa gctcagcttg taattgacgc aaagcaatat
    21721 aatgttccga atcattgaca tcatggcttt gatagtagaa gtggctagca aattcttggg
    21781 cttgctcggt actatctgcc aaatcaagga tggactcgac aactacagat tcaaaatatt
    21841 ccttactcca aggtctacgg gcagttccaa taacggcaaa gtgcttggaa agattgccgg
    21901 attgatatag tctaaaaagg gaagggtaga gcttgcgttt agccaggtct ccactcgcac
    21961 cgaaaattgt aacaataacc ttagatgaca tctagctacc taatttctat ttttattcct
    22021 agtcttgcta ggtatgagga aacctcattt cataaactta attctaacat aattttccga
    22081 aaaatcaaaa attccaatac gaggtagaaa aactgcaagg aaatccttac agtttgagtt
    22141 tagacgttta agaccttatc taagaactct ttcagacgag ggtgttgtgg gttatcaaag
    22201 atttggtcag gtgttccgtc ttcaaggaac tcgccatctg cagtaaagat aacgcggttg
    22261 gcaacctgac gagcaaatcc catctcatgg gttacgataa tcatggtcat gccttgctca
    22321 gccaattcct tcataacgtt aagtacgtct ccaaccatct cagggtcaag ggcagaagtt
    22381 ggttcatcga agagcatgat gtctggattc attgctaggc cacgagcgat ggccacacgt
    22441 tgtttttgac cacctgatag gctatctgga ttggcattag ctttatctgc tagtccaacc
    22501 ttttcaagca actccattcc caatttctca gcttcttcct tagtcatcaa cttgtgctca
    22561 ataggagcaa aggtgatgtt gtccaataca gacatatgag ggaagaggtt gaagtgttgg
    22621 aataccatgc cgatattttc acggacgtgg tcaacattgg ttgttttttc agttaaatca
    22681 tagccgttca cagtgatgtg accgctagtg acttcttcta aaagattgag gctacggagg
    22741 aaagttgact taccagaacc tgaaggaccg atgatacaaa caacatctcc ttcatagaac
    22801 ttagtcgtaa ttccttttag gacttcattt tttccatagt gcttgtgtaa atcatttaca
    22861 tcaattttta attttgccat taacgaatcc tcttttctaa gcgtttcgct agtctagtca
    22921 aaagtgtgat aattacaaga tagaagatag caaggattgc atacatcttg aaactttggt
    22981 agttacgagc aatgataatc ttaccagttt ggaagagttc aaccaaaccg atagcagata
    23041 cgatagttgt atctttaaga gcgataacga attggttgac aaagtttggc aacatcaatt
    23101 tagttgcttg tggcaagata atcttacgca tggtttttcc ataagagata cccaagcttc
    23161 ggctggcttc catttggcca actggaacgg cctgaatacc accacgaacg atttcagcga
    23221 tataagcagc cgcattgagt gagagggcaa ttgttccagc tacaaagtcg ttaattgggc
    23281 tttgttggcc tgtgatagac tcgatgaagt ttggaattcc ccagaagatg aaggctgcaa
    23341 gaatcatcaa tggaatacca cgaataacgt caacgaaaat ctcagagatg acgcgaagag
    23401 atttgtatgg gctaacgcta aacataccga agataattcc gatgacaatg gcaatagcaa
    23461 atgagataag agctagagca agagtgatac caagaccgct aaggagttgt ttgtagttgt
    23521 tttgaagcaa gccccagagc gttgtttcgt caacagtact tgttgaagca gttgaagatt
    23581 cgctagctag gtatttgtca agaatctttt ggaattcacc gtttgcttta aggtttgcaa
    23641 gtccgttgtt gaacatttca atcagttctg gatttgctcc ttttttaacg gcaaaggctg
    23701 tttcaccgat tggagttcca gagattggag ttttcaattt ttgaccttgg ctgatagaat
    23761 atttgagaac aggttcatca tccataacgg catcaatggc accagtgttt aaactgtcat
    23821 acattgaaga accatcagca aaggttttga ttttgtagcc gtatttgctt tgattttctg
    23881 ttaggaaggt ttgagaagca gttccgtttt taacaccgac tgtctttcct tttagatctt
    23941 cataagaagc aatattgctt gattctttga caccaagaat ggtattagca gtgtagtatg
    24001 attctgagaa gtcaaaagtt gccttacgag catctgtgac agacatacca gcgatgatac
    24061 catcggcttg accagcttgg acagcactga tagcagcatc aaaaccaggg ttggtgattt
    24121 caatttcaaa accttggtct ttagcgattg ccttaatcaa ttccatatca ataccagtgt
    24181 attggttgct tgaattttgg aaaacaaaag gtgcaaaaga agaatcgctg gcaatgatat
    24241 atttagcctt aacaggaata gcttttaatc ctgcgagagt agttgtagtt ggcactgctg
    24301 aagatgatga agcagtccat ttcttgataa ttttatcaag actaccatct tttttcattt
    24361 cagacaaggc ttggttaaat tcagtaacca ggtgctcgta tttacttcct tttttcacac
    24421 cgaaagcaaa acttcctaca gcttcaccat ccatttcaat atggaggtct tgaccttggt
    24481 taatggcata ttcgataaca ggtttgtcat ccatcatggc atcgatggca ccagcactca
    24541 agctgttgtt cattaaatca ccagtgtcaa atgttttaat agtaaagccg tatttatctt
    24601 tgattgtttc aaggaaacgt tgagcggcag ttccgttttt aacaccaacg gttttgccag
    24661 ttaattggtc gtacttgcta attttgtgtg actttgtagt agcaatgaca acttttgtat
    24721 catagtaagt atcagacatg gtgaagactt tttcacgttc tttagtcttt gtcatccctg
    24781 ccatgatagc gtcggcttgc ccagcttgaa ccgcattgac cgctgcgtca aatccaggat
    24841 aggacatctg aatgttccag cctttaatct cagcgacttt gttaataatg tcaacatcaa
    24901 ttcctttata agtttgatct gaatctttaa actcaaaagg tgcataggcg gtatcagaaa
    24961 caatcttaat cgtttctgct ttggcaatac ctaatgagaa aattgggaat aaaattagca
    25021 aaaatgctag aaattttttc ttcattttta gtctcctttt ccgaatattc tctcattata
    25081 tcagaaaaag taaaaaaagg caaattttta tattttcgtg tcagaaaata taacattgat
    25141 ttttcctttt ctttcttgaa ttgctattaa aaagtgctat aataatagta tatatagaag
    25201 aaaagaggac ggggatatga agaacaaaag aatatttaaa gacttccaag cttcaaaaat
    25261 gaatttaaac atttacacaa gccccttgtt agcctttgtt tttgtcttca taggagagtt
    25321 tgtggcttat actttatatg gtattagttt gttagctctc atcgggcttg ctagaaattt
    25381 tggagaggct ggtcaaaatc ttgcaagcta cttgcagacc ttgcatcaga gcttgatgga
    25441 taaaacaagt gactttcgtt taattttagg attactggcc tttggtttta ttcttaacac
    25501 tgtgttcaga tggacaagaa aagttgagaa aagacctatt cgaaccttgg gattttatag
    25561 agagaatttc ctcagcaatc ttctgaaagg atttagtcta ggcctggcac tttttcttct
    25621 gaccttgtta ggtttagtgg tcttagatca atatcgtttg gaatccattc acttgaatcc
    25681 ttattctctt gcctttgtcg tctttactat cccattttgg attttacagg ggacagcaga
    25741 agaagtggtg gcccgtgctt ggctacttcc tcaattggcc tcaagaacca atctaaaact
    25801 agctattctt atatctagcc tgttctttac cctgcttcat atgggcaatt ctggcctcac
    25861 ccctctatct ctagtaaatc tctttttatt cggagttacc atggctcttt accttctcaa
    25921 aactgataca gtttggggtg ttgcaggtat tcatggtgct tggaattttg ctcagggtaa
    25981 tctctttggg attttagtta gtggtcaacc gtcaggaacg tctctgatga cctttttacc
    26041 acaaggcaat caagattggc tatcaggtgg ttcttttggc atagaaggtt ccattatgac
    26101 aagtctggta ttactactgc tgattgtcta tcttgctaat aaattaaaga aagaaaatga
    26161 aaggatgtga cttcggtccg tccttttctt cgtgaaaata ctataagtat gctaaaatag
    26221 gaatagcaca tggagagagg attcttatga tcaatcacat tacagataat caatttaaac
    26281 tagtatcaaa atatcaacca tcaggagatc aaccccaagc tatcgagcag ttggtggata
    26341 acattgaggg gggagaaaaa gctcagattc tgatgggggc gactggaaca gggaagacct
    26401 atactatgag tcaggtcatt tctaaagtca ataaaccaac tctggttatt gcccacaata
    26461 aaactctggc tggtcagctc tatggggagt ttaaggaatt tttccctgaa aatgcagttg
    26521 agtatttcgt atcctactat gattattacc agccagaggc ctatgtccct tctagcgata
    26581 cctatattga gaaggatagt tctgtcaatg acgagattga caagcttcgc cactcagcta
    26641 cctcagccct tttggagcgt aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg
    26701 gtttgggttc gcccaaggaa tacgctgata gtgtcgttag tctccgtcct ggtctagaga
    26761 tttctcgtga taaactcttg aatgacttgg tcgatattca gtttgaacgt aatgatattg
    26821 atttccaacg cggaagattt cgcgttcgtg gggatgtggt agagattttc ccagcttccc
    26881 gagatgaaca tgcctttcga gtagaatttt ttggagacga aattgaccgt attcgtgaag
    26941 ttgaggctct gacaggtcag gtgctgggag aagtggatca tttagcgatt ttcccagcga
    27001 cacactttgt gaccaatgac gaccatatgg aagttgccgt tgccaagatt caagcagaat
    27061 tagaagagca gttagctgtc tttgagaagg aaggtaaatt gcttgaagcc cagcgcttga
    27121 aacaacggac agagtacgat atcgaaatgc tgcgcgagat gggctataca aatggggttg
    27181 aaaattattc tcgccacatg gatggacgta gtgaaggtga gcctccttat acgcttctcg
    27241 acttcttccc agatgatttt ttgattatga ttgacgagag tcatatgact atgggacaaa
    27301 taaaaggcat gtacaatgga gaccgttcgc gtaaggaaat gctagtaaat tatggtttcc
    27361 gtttaccgtc tgccttggac aatcgtcctc tccgtcgtga ggagtttgaa agccatgtgc
    27421 atcagattgt ttacgtatca gcgacacctg gtgactatga aaatgaacag actgagacgg
    27481 tgattgagca aatcattcga ccgacagggc ttttggatcc tgaggtggaa gtccgtccga
    27541 ctatgggaca gattgatgat ctcttaggtg aaatcaatgc ccgtgttgaa aagaatgaac
    27601 gaacctttat caccaccttg accaagaaaa tggcagagga cttgaccgac tatttcaagg
    27661 aaatgggcat caaggtcaag tacatgcact cggatatcaa gaccttggaa cggacggaga
    27721 ttatccgtga tctccgcttg ggtgtctttg atgtcttggt tggaatcaat ctccttcgtg
    27781 aagggattga cgttcctgag gttagcttgg ttgccattct cgatgctgac aaggaaggtt
    27841 tccttcgtaa cgagcgtgga ctcatccaga ctattgggcg tgccgcccgt aacagtgaag
    27901 gtcatgtcat catgtatgca gatacggtta cccagtctat gcaacgtgct atcgatgaaa
    27961 ctgcccgccg tcggaaaatt cagatggcct ataatgaaga gcatggtatc gtaccacaga
    28021 caatcaagaa agaaatccgt gacctgattg ccgtgaccaa ggcagttgct aaggaagagg
    28081 acaaggaagt cgacatcaat agcctcaaca aacaagagcg caaagaactc gtcaagaaac
    28141 tagaaaaaca aatgcaagaa gccgtcgaag tgcttgactt tgaactggcg gctcagatcc
    28201 gtgatatgat gttggaagtc aaggccttgg attaggggaa tagtatgatt tatttaagaa
    28261 agttaaagag agaagatttg atgtctttat gggaaatggc ttattcacaa cttaatccag
    28321 tttggaaaca gtatgatgct ccctattatg atgattatca gtatttttca aattttaaag
    28381 aattcgaact acaaaaatca gaatccattt taagcaactc aaatcgcctt ggtatttttg
    28441 ttgatgataa actagttggg actgtttcgc gttattgggt atgtaaacaa acaagatgga
    28501 tggaattggg aattggtatt tatgataaaa aattctggaa cactggtatt gggaaagttg
    28561 ctatgttgca gtggatagat aggacgtttc aggattactt ggagttggag catctgggtt
    28621 tgacaacttg gtcagggaat cttggtatga tgaaacttgc tgaaaaatta agaatgaaaa
    28681 aagaagctca tattccaaaa gttcgttatt atcaaggtaa atattttgat agtattaaat
    28741 atggtatttt gagagaagac tgggagaaaa taaatgacgg ttattataaa atcaatggaa
    28801 actcctgaag agatagaagg taaatccctc gttcactggc aaacgtggag agaggcttat
    28861 gatgaccttt tgcctgcaga atttcaggag acaatgacat tagaaagatg tcgattcttt
    28921 agtcaaaagt atccagaaaa tacattgatt gcgatagatg acgtgaaggt agttggtttt
    28981 atcagttatg gaaactttcg tgatgagact attcaagctg gtgaaattat tgctttatat
    29041 gttttaaaag actattacgg aaaaggcata gcacaaaagt taatgaaagc agctttgact
    29101 gctctgaatc atttttctga aattttctta tgggtattga aagataacaa gcgagccatt
    29161 gctttctatc aaaaaatggg ttttactttt gatggacaag aaaagatact tgaacttgga
    29221 aagcctataa aggaaaaacg aatggtattc tattctaaaa taattttaaa aagtagaagc
    29281 taatggcact ggtaccaagt ctgaaaattt aataaattag aaagcgagta aatttatgtc
    29341 ccgttcccaa ttaacgattt taacaaccat ttgtctgatt gaagacctcg aaacgcagcg
    29401 cgtggtgatg cagtatcgct ctcctgcaac caatcgctag tctggttatg cctttcctgg
    29461 aggtcatgta gaaaatggcg agtctttcgc agagtctgtc attcgtgaaa tctatgaaga
    29521 aacagggttg actatccaaa atcctcaact tgtcggcatt aaaaattggc cactagatac
    29581 aggtgggcgc tatattgtca tttgttataa ggcgactgag ttctctggta cccttcaatc
    29641 ttcagaagag ggagaagttt cttgggtgca aaaagaccag attccaaact tgaatctggc
    29701 ctatgatatg ctaccattga tggaaatgat ggaagctccc gacaagtcag agtttttcta
    29761 ccctcgccgt acagatctaa ctttcccatc tttgagatag cccttcacaa gatagacatg
    29821 agtacgcctt tctttgttgt tttaataaac gctctactcc attactccat atataaccaa
    29881 tatacaacaa atagttggga acaaactgtg gtagatgtcg aacgtcttcg
//
LOCUS       DAVHSI010000023        29258 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.023, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000023 DAVHSI010000000
VERSION     DAVHSI010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.023"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            148..606
                     /locus_tag="VVR21_001237"
     CDS             148..606
                     /locus_tag="VVR21_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6055124.1"
                     /translation="MYKMMLQPDLIRLDCSVSKHTELFQMVGKELEEKGYVTNQYLEA
                     LLEREQRFPTGLKTRFLNIALPHTDPEVIKEPFIFVVRNDKDLNMLQMGDNSDTPCQN
                     FLFLGIKDPKSQVGLLAKLMEIFSQEEFVQNFAQIKDGSEMYELLNQQLS"
     gene            634..936
                     /locus_tag="VVR21_001238"
     CDS             634..936
                     /locus_tag="VVR21_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6055125.1"
                     /translation="MARKLIVACGSGVATSTTIAEKIKTRFEDDGIDYPVEAVDYKSI
                     LNELPQASIYVYIAMPEQEVLDEAERLGVDVYPGVPFLTGMGADNVYEQIVESTNK"
     gene            968..2317
                     /locus_tag="VVR21_001239"
     CDS             968..2317
                     /locus_tag="VVR21_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU6055126.1"
                     /translation="MEIFQNVIQWILNLGSAIFVPLIIFVLGLMVGMNIKKAFISAIT
                     LGVAFTGMGMIIGFMSNAVSPASEALAINTGISLPALDLGWTGAASIVWSWGYAFAFF
                     AVQIIINIIMLSFNWTKTLNVDMWNVWGKALTGYLVYYVSGQLWAGFLVAGLQVVLEL
                     KLGDMFQKHIEDLTGIPLVTVTHGMILSAVFMLPVNKLMDKIPFLNKKADTNALRKKL
                     GIFSENSVMGFIIGVLLGFAGAYSVSNSLNLGIQVATAMALFPMVSKLFMQALSPLAE
                     SMSEFMKKRFNDREVFIGMDWPLLAGRSEVWVTLILMVPFFIGYSLILPGNAVLPIAG
                     VLNYSIAVGGLLLTGGNLARMMILGIIYLPLCLYSATYFAPILTGLANKTGAVEVEAG
                     KLITWSSLESPELRILFAESFNGNILAIGGAVAFLLLFVWLYKTMVTQEVPSKRYEN"
     gene            2307..2552
                     /locus_tag="VVR21_001240"
     CDS             2307..2552
                     /locus_tag="VVR21_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055127.1"
                     /translation="MKTSKTLWYSLLFVALVLFLLGLNSGQYLYNFLAIIISFIVYKY
                     GYSDLFREYDEKQRAKRETSEKIYHALREGKKKEENK"
     gene            2549..3301
                     /locus_tag="VVR21_001241"
     CDS             2549..3301
                     /locus_tag="VVR21_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEU6055128.1"
                     /translation="MTSGKILFEQERRAMAEAIELTFYRKNTNTAGGNFSFKTTDVNG
                     KEYIIMTPSMMSETYHGKVSAAQVLVLDLETQEVVAGEGKPTREINLHFACYETNPDI
                     KCVFHAHAPNAMFWATSHLDMPNLSEATQKVEYIKVLDFAPNTTPELAEIVRQELLEF
                     GNKLPKEYLLDSHGILVLTPGADGEEALNKALQIIDTVEWNAEIAYKQTIFQKLGILD
                     GYYSKGRKIGDIDDLINHRPIWNQEKKDEGFE"
     gene            complement(3411..4412)
                     /gene="galR"
                     /locus_tag="VVR21_001242"
     CDS             complement(3411..4412)
                     /gene="galR"
                     /locus_tag="VVR21_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU6055129.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTKLTLRESTLP"
     gene            4577..5755
                     /locus_tag="VVR21_001243"
     CDS             4577..5755
                     /locus_tag="VVR21_001243"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU6055130.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            5774..7255
                     /locus_tag="VVR21_001244"
     CDS             5774..7255
                     /locus_tag="VVR21_001244"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU6055131.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWETYVHYPE
                     QAIQDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            7325..7729
                     /locus_tag="VVR21_001245"
     CDS             7325..7729
                     /locus_tag="VVR21_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU6055132.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            7886..8740
                     /locus_tag="VVR21_001246"
     CDS             7886..8740
                     /locus_tag="VVR21_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEU6055133.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            8766..9536
                     /locus_tag="VVR21_001247"
     CDS             8766..9536
                     /locus_tag="VVR21_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU6055134.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            9523..10389
                     /locus_tag="VVR21_001248"
     CDS             9523..10389
                     /locus_tag="VVR21_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEU6055135.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(10476..11738)
                     /locus_tag="VVR21_001249"
     CDS             complement(10476..11738)
                     /locus_tag="VVR21_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU6055136.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIAAALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(11738..12319)
                     /locus_tag="VVR21_001250"
     CDS             complement(11738..12319)
                     /locus_tag="VVR21_001250"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU6055137.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(12719..12814)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(13197..13436)
                     /locus_tag="VVR21_001251"
     CDS             complement(13197..13436)
                     /locus_tag="VVR21_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6055138.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(13436..13579)
                     /locus_tag="VVR21_001252"
     CDS             complement(13436..13579)
                     /locus_tag="VVR21_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU6055139.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(13591..14418)
                     /gene="xth"
                     /locus_tag="VVR21_001253"
     CDS             complement(13591..14418)
                     /gene="xth"
                     /locus_tag="VVR21_001253"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU6055140.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            14552..15006
                     /locus_tag="VVR21_001254"
                     /pseudo
     CDS             14552..15006
                     /locus_tag="VVR21_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            15078..15455
                     /locus_tag="VVR21_001255"
     CDS             15078..15455
                     /locus_tag="VVR21_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU6055141.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVALKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            15661..17406
                     /locus_tag="VVR21_001256"
     CDS             15661..17406
                     /locus_tag="VVR21_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6055142.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYTIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKEMRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMAGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            17396..19147
                     /locus_tag="VVR21_001257"
     CDS             17396..19147
                     /locus_tag="VVR21_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055143.1"
                     /translation="MQNKQEQWAVLKRLMSYLKSYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYELLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            19321..20013
                     /locus_tag="VVR21_001258"
     CDS             19321..20013
                     /locus_tag="VVR21_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6055144.1"
                     /translation="MLKWEDLPVEMKSSEVEFYYQLVSKRKGSLIFKRCLALVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVMDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMLATLLL
                     PAGITSPASINYKDEDTIISQMTEKGLSADQAYVEHVLPEKMRYNLAYLREFSFLGDI
                     KIMFQTVFEVLK"
     gene            20056..21282
                     /locus_tag="VVR21_001259"
     CDS             20056..21282
                     /locus_tag="VVR21_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU6055145.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILHVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTLEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVENKRDLFVASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPAID
                     DEEMYKEFQILSLHGQTEDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            22412..24499
                     /gene="pfbA"
                     /locus_tag="VVR21_001260"
     CDS             22412..24499
                     /gene="pfbA"
                     /locus_tag="VVR21_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU6055146.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSLSVNSISSNGTIRSNSQLDNRTVESTVTS
                     TNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAIQDAIDAAAQGLGG
                     GNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIVFMTGLFTDDGAQV
                     EWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNSNNVTIKNVTFKDS
                     YQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEPLTRKGFPYALNDD
                     GKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKILNNHFDNMMYAGVR
                     FTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLLDLNKQVVIAENIF
                     NIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNIELLRVSDNLVVSE
                     NSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKEPVIRDSDGNFNIV
                     TENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNREFNSSKDNRQMNDKIDN
                     KQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKIMELFLTVTGIGLL
                     LTLKGLKYYGKDK"
     gene            24483..24779
                     /locus_tag="VVR21_001261"
     CDS             24483..24779
                     /locus_tag="VVR21_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055147.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            25014..25328
                     /locus_tag="VVR21_001262"
                     /pseudo
     CDS             25014..25328
                     /locus_tag="VVR21_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            25505..26164
                     /locus_tag="VVR21_001263"
     CDS             25505..26164
                     /locus_tag="VVR21_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU6055148.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPIITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            26189..27256
                     /locus_tag="VVR21_001264"
     CDS             26189..27256
                     /locus_tag="VVR21_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6055149.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDAKEMPKDWT
                     ELASKYKGQYSIYGLTGGTGRAIYASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESTVVKVLDKENAIQYGMIWGSGALVGQKEQNVVFKVMSPEIGVPFVTEQTMILS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            27359..28369
                     /locus_tag="VVR21_001265"
     CDS             27359..28369
                     /locus_tag="VVR21_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055150.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            28381..>29258
                     /locus_tag="VVR21_001266"
     CDS             28381..>29258
                     /locus_tag="VVR21_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6055151.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKP"
BASE COUNT         9156 a         5056 c         6204 g         8842 t
ORIGIN      
        1 gtttataaca aaaaatatca aaagataaca aaaaataaca attaaagcat tgacttttta
       61 aatgaaaacg cttataatta cattataaca aaaaataaca gaatgttaac aataaattta
      121 acgttttttt aaaaaaggag ttgtgatatg tataaaatga tgttgcaacc ggatttgata
      181 cggttggact gtagtgtatc gaagcataca gaactattcc aaatggttgg aaaggagttg
      241 gaagaaaagg gatatgtaac aaatcaatac ttggaggctc tattagaaag ggaacagcgt
      301 tttcctacag gcttaaaaac acgattttta aatatcgcac ttccccacac agatccagaa
      361 gtcatcaagg agccatttat ttttgttgtt cgcaatgata aagacttaaa tatgttgcaa
      421 atgggtgata actctgatac tccttgtcaa aactttctgt tcttaggtat aaaagatcct
      481 aagagccagg ttggtctctt agctaaacta atggaaattt tttctcaaga agaatttgta
      541 caaaacttcg ctcaaataaa agatgggtcg gaaatgtatg aattattaaa tcaacaacta
      601 tcataaacaa aagcctaaaa aggagaataa aaaatggcaa gaaaattaat cgtagcatgt
      661 ggaagtggtg tagcaaccag tacaacaatt gctgaaaaaa tcaaaacacg ctttgaagat
      721 gacggtatcg actatcctgt agaagcagta gattacaaat cgatcttaaa tgaactacca
      781 caagcaagta tctacgtcta tattgctatg ccagaacaag aagttttgga tgaagccgag
      841 agactggggg tagatgttta tccaggtgtt ccattcttaa ctggaatggg tgcggataac
      901 gtatatgagc aaattgttga gtctacaaat aaataaaata taaaaataaa ttaaggagaa
      961 aaaggttatg gaaatctttc aaaatgttat tcagtggatt ttgaatttag gatctgcgat
     1021 ttttgtacca ttgataattt tcgttttagg tttaatggtt ggtatgaata ttaaaaaagc
     1081 ctttatttca gccattactc tcggggttgc ctttacaggt atgggaatga tcattggatt
     1141 tatgtcaaat gcggtgtcgc cagcttctga ggctctagct ataaatacag gaatttctct
     1201 cccagctctt gacttgggtt ggactggtgc ggcaagtatt gtatggtcat ggggttatgc
     1261 cttcgcattc tttgctgtac aaatcattat caatattatt atgctcagtt tcaactggac
     1321 aaagactctt aatgtggata tgtggaatgt ttggggtaaa gccttaacag gatatcttgt
     1381 ttactatgtc agcggtcagt tgtgggctgg tttccttgtg gcgggattac aagttgtgtt
     1441 agagctaaag cttggagaca tgttccaaaa acatattgag gatttaactg gtattccgct
     1501 ggtaactgtt acacatggta tgattctttc cgcggtattc atgttgcctg ttaacaaatt
     1561 gatggacaaa attccattct tgaataaaaa agctgataca aatgctcttc gtaaaaaatt
     1621 gggtatcttc tctgaaaact ctgtaatggg attcattatt ggtgtgcttc tcggatttgc
     1681 aggtgcctat tctgtatcta attccttaaa tttgggtatc caagttgcga ctgcgatggc
     1741 gctattccca atggtaagta aactcttcat gcaggccctt tcaccactgg ctgaatctat
     1801 gagcgaattc atgaagaaac gctttaatga ccgtgaagta tttattggaa tggactggcc
     1861 attgttagca ggtcgctcag aagtttgggt aacgttaatc ttgatggtac cattctttat
     1921 tggctattct cttatcttgc caggaaatgc agtgctccca attgcaggtg tcttgaacta
     1981 ctctatcgct gtaggcggac tattgctgac aggtggtaac ttggcacgta tgatgattct
     2041 aggtattatt tatcttccgc tttgtctcta cagtgctact tatttcgcac caatcttgac
     2101 agggttggcc aataagaccg gagcagtcga agttgaagct ggtaaattga ttacttggtc
     2161 atcacttgaa tcgccagaat tgcggattct cttcgcagaa agctttaatg gtaatatttt
     2221 agccatcgga ggggcggttg ctttcctatt actttttgta tggttgtaca aaacaatggt
     2281 aacacaagaa gtaccgtcaa aacgttatga aaactagtaa aactctttgg tacagtctct
     2341 tatttgtagc tcttgtctta tttttgctag gtttaaatag tggccaatat ctttacaatt
     2401 ttttagcgat tatcatcagt tttatcgtct ataaatatgg ctacagtgac ttatttagag
     2461 aatatgatga gaaacaacgt gcgaagagag agacatctga aaaaatctat catgctttac
     2521 gagaaggaaa aaagaaagag gaaaataaat gacaagtggt aaaattttat ttgaacaaga
     2581 aagacgcgct atggctgaag ccatcgaact gactttctat cgcaaaaaca ccaatactgc
     2641 tggaggaaat ttctccttta aaacgacaga tgttaatggt aaagaataca tcattatgac
     2701 accgtccatg atgtctgaaa cctatcacgg gaaagtatcg gctgctcaag tgttggtgct
     2761 ggatttagaa actcaagaag tggttgctgg agaaggcaaa ccgacacgcg aaatcaacct
     2821 tcactttgct tgctatgaaa ccaacccaga tatcaaatgt gttttccatg ctcatgcacc
     2881 aaatgcaatg ttttgggcaa ctagccactt agatatgcca aacttatctg aagctactca
     2941 aaaagttgag tatatcaaag ttttggattt tgccccaaat actacacctg aactggctga
     3001 aattgtacgt caagaactcc tagagtttgg caacaaattg ccaaaagaat acttactaga
     3061 cagtcatggt attttggtat tgacaccggg tgctgatgga gaagaggctt tgaataaagc
     3121 ccttcagatt attgatacag ttgaatggaa tgctgaaatt gcatacaagc agacaatctt
     3181 ccaaaagtta ggaattttgg atggttacta ttctaaaggt cgtaaaattg gagatattga
     3241 tgatttaatc aatcatcgtc caatttggaa tcaagaaaag aaagacgaag gtttcgaata
     3301 aactatttgg gaggaggata ggcacgtgct atcttccttt ttaaaaaaga aatcctaatg
     3361 gatatttgag aatctctatt aggatttttg gtcttattat attagttgag ttatggcaga
     3421 gtactttctc ttaacgtcag tttggttccc aacatggtca ggctaggtat tttccgaccg
     3481 tggagtactt ccttgttaag aatatccata cctgctcgcc ccatttcttc agtataaact
     3541 gtaatactag agaggggagg atagacctgt ttggtcagac tggtgtcgtt gaatgaaatg
     3601 aggctgacgc gatctggcag gctgattcca gcttcttgga gggcacggag ggcaccgata
     3661 gctaaactat cgctggctgc gaaaaatgct ggcggaagtt ggtctcccaa gctctgaatg
     3721 gcctccttca ttaagtcata gccagactgg gcagtaaatc ttccttgaaa gaccagttca
     3781 tcatgataga ttcccctcgc ttgactgtag tttttgaagt tttctagacg cttgtcctga
     3841 atgatttctt cttggtctgt tgtttcctca agccctgtta gaatcccgat gcggtccatc
     3901 ccttgactga ggaaataatc gacaacctgt ttcatagcag tgtaaaaatc cgtgataata
     3961 caggtatgtc ccagggaaag tgtatcgctg tctagaaata caagaggctt ttggtattct
     4021 tcaaaggcag aaatctgagc tcgactaaac tttccgatgc agagaatccc aatcacttcc
     4081 tcgcttaagg taaaaggatg gtcattaaaa tagcgcaaga tatcatagtc caactcttgg
     4141 gctctttttt ctattcctag gcgaatctgg tagtagtaga ggtcgtctag ctccccttgt
     4201 tcgctgaccc attggataat ggcaatcttt tgcttgggtt tgtgggactc gcctgtcttg
     4261 aggtgcttgg tgtagcccag ctcttcagca acggttaaaa tacggtgtct ggtttcttct
     4321 gtaacagata ggctctggtc gcggttgagg acacgggata cggtcgcgat tgagacagag
     4381 gctagctgtg caatgtcttt taaggtagcc ataaatcctc cttgattagg ttagtatatc
     4441 atatttttct tctttttact gatattttag taaaatttta gtaaaaagga ttgaccttgg
     4501 gaaattcctt ggatacaata gaaagaaaac gattacacgt taagatggct taacggacag
     4561 tcaaaggaga attcatatgg cacaacatct tactactgaa gtccttcgca aagactttct
     4621 tgctgttttt ggtcaagaag cagaccaaac cttcttttca ccaggccgta ttaatttgat
     4681 tggtgaacac acagactaca acggtgggca cgtttttcct gctgctattt ccttgggaac
     4741 ttacggtgca gctcgtaagc gtgacgacca agtcttgcgt ttctactcag ctaactttga
     4801 ggacaagggc attatcgaag tgcctctcgc tgacctcaag tttgaaaaag agcacaactg
     4861 gaccaattat ccaaaagggg ttcttcattt cttgcaagaa gctgggcacg tgattgacaa
     4921 aggttttgat ttttatgttt atgggaatat cccaaatggt gctggcttgt cttcttcagc
     4981 atccttggag ctcttgacag gagtcgtggc agagcatctc tttgatttaa aactagaccg
     5041 tttggatttg gttaaaatcg gaaaacaaac agaaaataac tttatcggag tcaactctgg
     5101 tatcatggac cagtttgcta ttggtatggg ggctgaccaa cgtgctattt acttagatac
     5161 caatacttta gaatacgact tggtgccact tgatttgaag gacaatgtcg ttgttatcat
     5221 gaacaccaac aaacgccgtg aattggcgga ctctaaatac aatgaacgtc gtgctgagtg
     5281 tgaaaaagca gtggaagaat tgcaagttgc cttggatatt cagaccctgg gtgaattgga
     5341 cgagtgggcc gttgaccaat atagctattt gattaaagat gaaaatcgtt tgaaacgtgc
     5401 tcgccatgct gtgcttgaaa accaacgtac ccttaaagct caagcagccc ttcaagcagg
     5461 tgatttggaa acatttggtc gtttgatgaa tgcgtcacac gtttctctgg agcatgatta
     5521 tgaagtaact ggtttggaat tggatactct tgttcacaca gcttgggcac aagaaggagt
     5581 tctcggtgct cgtatgacag gggctggttt tggtggctgt gctattgcct tggttcaaaa
     5641 agatactgtt gaggccttta aggaagctgt aggcaaacac tacgaggaag tagttggata
     5701 cgctccaagc ttctatatcg ctgaagttgc aggtggcact cgcgtccttg actagtcaaa
     5761 aggaggctct atagtgatct tagtagataa atttgtaaca catgtcattt ctgaaagttc
     5821 atttgaggaa atggatcgaa tctacctgac caaccgtgtt ttggcacgag tgggagaagg
     5881 tgttttggaa gttgagacca atctggataa attgattgac ctcaaggacc agctagttga
     5941 ggaagccgtt cgattagaga cgattgagga tagtcagact gcgcgtgaaa tccttggtac
     6001 tgaactgatg gacttggtga ctccttgtcc gagtcaggtc aatcgtgact tctgggaaac
     6061 ctatgtccac tatcctgagc aagcgataca ggatttttat caactcagtc agaaaaatga
     6121 ctacatcaaa ctcaaggcca ttgctaaaaa tatcgcttat cgtgttccat ctgattatgg
     6181 agaacttgaa attaccatca atctctctaa gcctgaaaag gatccgaaag agattgcggc
     6241 agccaagttg gtgcaagcta gtaattatcc tcagtgtcaa ctttgtttag agaatgaggg
     6301 ttaccatggt cgggtcaacc acccagctcg cagcaaccac cggattatcc gttttgaaat
     6361 ggttggtcag gaatggggtt tccagtattc gccctatgct tactttaatg agcattgtat
     6421 ctttttagat ggccagcatc gtcccatggc cattagtcgt cagagttttg aacgtctgtt
     6481 ggctatcgta gagcagtttc caggatattt tgctggatct aatgccgacc tgccgattgt
     6541 ggggggctct attctaactc atgatcatta tcagggaggc cgtcacgtat ttcctatgga
     6601 attggctccc ttgcaaaaga ccttccgatt tgctggtttt gagcaggtca aggctggaat
     6661 tatcaagtgg ccaatgtctg tcctacgctt gacttcggat tccaaagagg atttgattaa
     6721 cttagctgat aagattttcc aggaatggcg tcagtattca gattctagtg tgcagatttt
     6781 agcagagaca gacgggacac cgcatcacac catcacacca atagcgcgta agcgtgatgg
     6841 acagtttgag ttggacttgg tcttgcgaga caatcagact tcagcagagc atcctgatgg
     6901 catctatcat ccccacaagg atgtccaaca tatcaagaag gaaaatatcg gcttgattga
     6961 ggtcatgggc ttggcaatct tgccaccacg tctgaaagaa gaagtagagc aagtcgctag
     7021 ctatcttgta ggagaagctg ttacagttgc cgattatcat caggagtggg cagaccaact
     7081 caaatcccaa catccagacc taacggataa agaaaaagcc cttgcaatcg tcaaggactc
     7141 tgtgggtgct atctttgcgc gtgtacttga ggatgcagga gtctacaagc agacagaaca
     7201 agggcagaca gcctttatgc gctttgtgga acatgtcgga attttactag actaggagct
     7261 ttctccttgc acagtcctat aaaaagtagt atcatagtgt catttgaaat atcaggagga
     7321 aacgatgaaa gactttcatt ttgacgctat atctgccttt gaaaattacg aaattgaaaa
     7381 aatgagagat ggtcacgttg tggtgacgac caaagtagtg aactcgtcgc tcaactacta
     7441 tggcaatgcc catggtggct atctattcac actatgtgac caaatcagtg gtttggtggt
     7501 tatctcgctg ggacttgatg gggtgacact ccaatcctct atcaactacc ttaaggcagg
     7561 aaaactcgac gatgtattga ccattaaagg agaatgtgtc catcaaggtc gtacaacctg
     7621 tgtgatggat gtggatatca ccaatcaaga gggcagaaat gtctgcaaag caacctttac
     7681 tatgtttgtc acaggccaaa ggtctgagga aagacgggta aggatataaa gagtaattta
     7741 atagagtgag gtgaattttg gaatttataa gatttgcctt actcattttt ttatattgat
     7801 atgatttaat tctaaaatag aaaatttagt aatgtggtag aaaatacaag agttgtgttt
     7861 taatttctat ggtataatta aaagcatgaa gataaaagaa ataaagaaag ttactttaca
     7921 accgttcacg aaatggacag gtggtaaaag acaattattg cctgttatta gagaattaat
     7981 gcctaaaacc tataacaggt atttcgaacc ttttgttgga ggtggagctt tattttttga
     8041 tttggctcct aaagatgcag ttattaatga ttttaacgct gaactaataa attgctatca
     8101 acaaattaag gacaatcctc aagaattgat tgaaattttg aaagttcatc aggaatataa
     8161 ttcaaaagaa tattatttag atttacgttc tgcagatcgt gatgaaagaa tagatatgat
     8221 gtccgaagta caaagagctg cacgtattct atatatgttg agagtgaact ttaatggtct
     8281 atatcgtgtg aattctaaga accaatttaa tgttccatat ggacgttata agaatcctaa
     8341 aattgttgat gaggaattga tatctgctat ttcagtttat ctaaataaca atcaactaga
     8401 aattaaagtg ggagattttg aaaaggcaat tgtagatgtt cgaacaggag attttgtgta
     8461 ttttgaccct ccatatattc cattgtctga gacgagtgca tttacgtctt atactcatga
     8521 gggattctct tttgcagatc aagtaagatt aagagatgcc tttaagagat tgagtgatac
     8581 aggagcttat gttatgttat caaattcttc tagtgcttta gtagaggagt tgtataagga
     8641 ttttaatata cattatgttg aagctacccg aactaatgga gcaaaatctt caagtcgagg
     8701 aaaaatttct gaaattatag tcacaaatta tgaaaaataa cgaatataag tatggaggtg
     8761 ttcttatgac aaaaccatac tacaataaaa ataagatgat tcttgttcat tcagatacgt
     8821 tcaagttctt atcaaaaatg aaaccagaaa gtatggatat gatttttgct gatccacctt
     8881 attttttaag taatggtgga atatctaatt ctgggggaca agttgtttct gttgataaag
     8941 gagattggga taaaatttct tcattcgaag aaaaacatga gtttaatcgt aaatggattc
     9001 gcctagcaaa agaagttctg aagcctaatg ggacggtatg gatttcaggt agtttgcaca
     9061 acatatactc agttggaatg gcattagaac aagaaggttt taaaattctg aataatatta
     9121 cttggcagaa aacaaaccct gcccccaatt tatcttgtcg ttattttacc cattctactg
     9181 aaaccatttt atgggccaga aaaaatgata aaaaagctcg tcattactac aattatgatt
     9241 taatgaaaga attgaatgat ggaaaacaaa tgaaagatgt ctggacgggt tctttaacaa
     9301 agaaagttga aaaatgggct gggaaacatc caactcaaaa accagagtat ttgttagaac
     9361 gcattatttt agcctctact aaagagggtg actatattct agacccattt gttggtagtg
     9421 gcactacggg tgttgttgcg aagcggttag gtagaagatt tataggtatc gatgctgaaa
     9481 aagaatattt aaaaattgca aggaagaggt tggaggcaga aaatgaaaca aactagaaat
     9541 tttgatgagt ggttgtcaac gatgaccgac acagtagctg actggactta ttatacagat
     9601 tttcccaagg tttataaaaa tgtatctagt ataaaagttg ctctaaatat tatgaatagt
     9661 cttattggta gtaaaaatat acaagaggat tttttagact tatatcaaaa ttatccagaa
     9721 attttgaaag ttgtgcctct acttattgct aaacgtttga gagatacgat tattgttaag
     9781 gatccgataa aagatttcta ttttgatttt agtaaacgaa actatagtat tgaagaatat
     9841 actatgtttt tggaaaaatc aggtatattt gatttattgc aaaatcattt agtatcaaat
     9901 ttagttgact acgttacagg tgttgaggtt ggtatggata ctaatgggcg caaaaatcgg
     9961 actggagatg cgatggaaaa tattgttcaa agttatcttg aagctgaagg gtatatttta
    10021 ggagagaatt tatttaaaga gattgaacaa aatgaaatag aggaaatttt ttctgtcgat
    10081 ttatctgcta ttacgaatga tgggaatact gtgaaacgtt ttgattttgt cataaaaaat
    10141 gaacaagtgc tttatctgat tgaggttaat ttttattcag gaagtggttc aaaattaaat
    10201 gagacggcta gatcttacaa aatgattgct gaagaaatta aagctattcc taatgttgag
    10261 tttatgtgga ttactgatgg acaaggttgg tataaggcta agaataattt acgagaaaca
    10321 tttgatattt taccattctt atataatatt aacgatttgg aacataatat tttaaagaat
    10381 ttgaaatagg tccaattcaa ttagatggga attgggattg attgtattta taatcaattt
    10441 gtgataaaca aaaaagaggc tcgcacctct ttttcttatt tctttttatg atttaatacg
    10501 gcattgagga caatggcgag taggctggct acgacgattc cgtttgagaa gaacatttgg
    10561 aaggctgtcg gcatgctgac aaagagatta ctgttgttga gaccgacacc tgcagcgatt
    10621 gaaacagctg cgataaggaa gttgtgttca ttgttagcaa agtcaactcg ggctaggatt
    10681 tgcatccctt gaatagatac aaaaccaaac atcaccagca tggcaccgcc gaggacggag
    10741 cttggaatga tttgggcaag ggcaccaaac ttaggaagca gtccaaggag aaccaggaaa
    10801 ccagctgcgt agtagattgg caggcgtttt ttgatgcctg acaatttaac caaaccaacg
    10861 ttttgtgaaa atccggtgta agggaaggtg ttaaagattc ctccgagaag tacggccaaa
    10921 ccttctgcgc ggtaaccgtt gcgaaggcgc gtgctgtcga ttggatcttt tgtgatatca
    10981 gacaaggcta gataaacacc agttgactca accatagaca ccgttgcgat gatacacatc
    11041 atgacaatag atgagatttc aaaggttggc atcccaaagt agagtggagt tgggacatgg
    11101 acaagtggag ctaccgcaac aggagagaag tccaccaagc ccatagtagc agcaatggca
    11161 gttccaacaa ccagaccaat caaaatagag atagacttga taaatccttt ggtaaagatg
    11221 ttgatcaaga ggataatcag aacagtaata gctgaaagca agagactttg accagttggc
    11281 tctggaacgt tatttcccat atttccaata gcgacaggga tcaaggttaa accaatcgtg
    11341 gtaataacag atcctgttac gatagagggg aagagattgg ccacttttga gaagatgcct
    11401 gaaacaagaa ccacgtaaat cccagatgcg ataagggcac caaacatagc gccactacca
    11461 tggctttgcc caatcataat caagggagcg accgactgga atgcaactcc aagaacgact
    11521 gggagtccaa tcccaaagta tttgttgagt tggagttgga ggaaggttgc caccccacac
    11581 atgaagatat ctgtagaaat caggtaggtc aactgctcag ctgaatagcc aagggctgcc
    11641 gcaatcatga tgggaaccag gatagatcct gagtacatgg ctagtaagtg ctgcaagcca
    11701 agaacggctg cttgcgagtg tttttcttga gtttgcatta gagatctgcc tccttaaata
    11761 cgacctgacc attttcaaaa cgatccaaac gagcaagtga taggacaggg tagcctgctt
    11821 tttcaagcaa atcacggcca tcttggaagg atttctcaat cacgataccg atagcttgga
    11881 ctgtggcacc ggcctgttcg atgatttgaa tcaagccttt agcagcttgg ccattagcaa
    11941 ggaaatcgtc gataatcaaa accttatctt ctggtgagag gaattttcca gcgatagaaa
    12001 cggtgctggt cacctgtttg gtaaaggagt agacttgagc agttaagatg ccttcgttca
    12061 tggtgatgtt cttagctttt ttggcgaaaa tcatgggaac gtttaaggct tcagctgtaa
    12121 aaacggctgg ggcaataccc gacgcttcaa tggttacgac cttggtaatg ccagtagcag
    12181 caaatttttc cgcaaaaacc ttaccaatct ctcgcatcaa gctaaagtca acttggtggg
    12241 ttaaaaagga atctaccttg aggatgttat cacccaagat atgcccatcc ttgaggatgc
    12301 gctcttctaa taatttcata agacctccta aagtctaaaa gttaatttac ttgttgttta
    12361 aatatttcta tagtgatccc ttttgctaat actatatatt tgataaaact attacgagcg
    12421 aagcgagtct tatcaaatat ttcccgttgt agtggtatca tagacaatga tcttgttatt
    12481 gtctatgacg ggatttttga gagtaaaata gttcggggaa ctattttagc ctaagcctag
    12541 aaatgaaaga gctaggggct caaaaattag ggatgaaatt ccctggattc ctgaaattat
    12601 tcacaggata atttcacctc tcgtccgcac taattaaggg aaatattaaa aatattcaaa
    12661 aaagacctac ttaatctcta agtaagtccc ctaaatagac atggcaaaaa cggccatatc
    12721 tcactgctga cttacttatt gttaggtgtt ccggcacctt gtagaaacgt cgtgccaatt
    12781 cacgacataa acaagtaaaa cgatattcaa ttttaaatag gcttgagcca atgtttttat
    12841 tttacactaa ataactttag aaatcaacta ttttgttagt gttttggttt aaaaaacgaa
    12901 caaacagaag agagggtgaa caaaaactcc gttgtaagct aacatttata ctaaatgaaa
    12961 atcaaagagc aaactaggaa gctatccaca acctcaaaac actgttttga ggttgtggat
    13021 agaattgaca gagtcagtat catataccta cggtaaggcg atgttgacgt ggcttgaaga
    13081 gattttcgaa gagtattaga agatttttcc atcataaaag gcatactatc aagtttttag
    13141 acacctgaca atatgccttt ttctaacttt aaagactttt cccaattttt attattctac
    13201 tcgctaaatc ttaaaaaata gccatctgga tccaaaactg caaatttatg aggatagata
    13261 tagggatcac tgacacgaaa ctttcttttg gtcaagggac gataaatagg atagtttgcc
    13321 tccatcactt tttgatagag ttttggaaca tcctttatgc caaaggagag attgactcca
    13381 cgaccaaagg ggtaggtcag ttcagctagt tgatcctttg ttccctcctc taacattagt
    13441 tgacactctt caagagaaag agaaagtttt cttctggacg ttggtattca atcctaaaac
    13501 ccagtaaacc acagtagaag gaccgggact gttcgatatt cgatacaaga aactcgggaa
    13561 tgaccgcatt gtagtccata tagaaaatcc ttacaagtca atttccaaga caatcggtgt
    13621 atggtcttgg cgagcacctg agtcaatcat atcagattta gtgaccttgt cagcgatacg
    13681 gttacttgtg agccagtagt cgattctcca gcctgtattg ttgattttag aagttttgct
    13741 gcgttgtgcc caccaagtgt agcgttcagg aacatcgcca tgaacatggc ggaaggtatc
    13801 agtaaatcca gttgccaata ggttggtaaa tccagcacgt tcctcgtcag taaatccagg
    13861 tgaacggcgg ttgctagcag gatttgcaag gtcgatttca ttgtgggcta cgttgtagtc
    13921 accggtcgca aggactggtt tttctttgtc tagttcagcc aaatactccg catatttgac
    13981 atcccagact tggcgttctt ccaagcgttt aagaccatcg ccagcatttg gtgtgtaaac
    14041 ttgggtcacg aaaaatgcat caaattctag agtgatgatg cggccttcca agtccatggt
    14101 agaaggggca ccgatttctg ggaaagtgac agtgggtgta agttctttct tataaaggaa
    14161 catggttcca gcatagcctt tacgggcagg ctcttgggaa gagcgccacg tgttttcgta
    14221 gcctgggaag agttcttcta aaatttccac gtgtttcttt gtaggtcctt tggcagaaag
    14281 cttggtttct tggatagcaa tgatatcagc attttcagcg accaaggttt gtaggacttc
    14341 ttgggacaat ttggcacgag ctgagtcact agttagggca gcgtttaggg aatcaatatt
    14401 ccatgagata agtttcataa agttaccttt ttcattcaga ttatagattt tattatacca
    14461 aaaaaagatc tatttcccca acgtatggtt tgaaaaatta ctctctttcg tttataatta
    14521 agaatgattt tatgaaaggg agtgaaaata catgaaattc tactcttatg actatgtact
    14581 cagccaaatc ggtcagcaaa atggtatcat ggttggcttt gggattgttc tattagctgt
    14641 gacagttttt ttgctttcaa ggcataccat gataaaaagg aaccgaattt cgtgagttgg
    14701 tcatgatttc agctctggcc ttatttagct ctgcttttgg tcagcatcac gacttatcaa
    14761 aacaatcaag tttctaacaa taaatttcaa acttcacttc atttcatcga ggttgtttcc
    14821 aaagatttgg gagtagacaa gtcagaagtc tatgttaata cttccacaaa cacagatggc
    14881 gcacttatca aagtgggaga tcgctattat cgtgccctaa acggaagtga gccagacaag
    14941 tacctgttag agaaagtcga attgtataag acagacgcaa ttgaactggt ggatgtgaac
    15001 aaatgacact taattatatc gaaattttaa tcaaactggt cttgactctc aaatagctca
    15061 acaacaatgt tcactttgtg aaacgtttga ttgatggtaa gccaactctc cttatcaaaa
    15121 atgggaatat tgacccagaa gcctgtcgtt cagttggttt gtctgcatcg gatgtagccc
    15181 tcaaacttcg tagccaaggg attttccaga tgaagcaagt caaacgagct gtgcaagagc
    15241 aaaatggaca acttatcgtt gtgcaaatgg gagatgaaaa tcctaagtat ccagttgtga
    15301 ctgacggtgt gattcaagta gatgtcttgg aatcgattgg tcgtagcgaa gagtggttgc
    15361 ttgataacct cagtaaacaa gggcatgaca atgtagccaa tatctttatt gctgaatatg
    15421 acaagggtgc tgttacagtc gtaacttatg aataagaaaa acctggggtc ttgtactctt
    15481 cgaaaatctc ttcaaaccgc gtcaacgtcg ccttgccgta tgtaggttac tgacttcgtc
    15541 agttctatct acaacctcaa agcagtgctt tgagcagcct gcggctagtt tcctagtttg
    15601 ctctttgatt ttcattgagt attggcctca ggtttccatt tgcaatcaga aagggatttt
    15661 atgtccatta ttcaaaaact ctggtggttt ttcaagttag aaaaacgccg ttatctagtc
    15721 ggaattgtgg ccctggtctt ggtttccgtc ctcaatctca ttcctcctat ggttatgggg
    15781 cgagtcattg atgccatcac atcggggcaa ttaacccagc aggacctcct tcttagccta
    15841 ttttacttgc tacttgcagc ctttggtatg tactatttgc gctatgtgtg gcgtatgtat
    15901 atccttggga cctcttattg cttgggacag atcatgcggt ctcgcttgtt taagcatttc
    15961 acaaaaatgt cgtcagcctt ttatcaaacc tatcggacgg gtgatctgat ggcacacgca
    16021 accaatgata tcaatgcctt gactcgttta gcaggtggcg gtgtcatgtc tgcggtggat
    16081 gcctctatca cggctctggt gactttgttg accatgctct ttagcatctc atggcagatg
    16141 actcttgttg ccattctccc cctacctttc atggcctatg cgactagtcg cctagggaga
    16201 aagactcata aggcctttgg cgaatcccaa gctgcttttt ctgaactcaa taacaaggta
    16261 caggagtccg tatcaggtat caaagtgacc aagtctttcg gttatcaggc agacgagttg
    16321 aagtcttttc aggcagtcaa tgaattaacc ttccaaaaga acctgcaaac catgaaatat
    16381 gatagtctct ttgaccctat ggttctcttg tttgttggtt cgtcctatgt tttaacgctt
    16441 ttggttggct ccttgatggt tcaggaaggg cagattacag ttggtaatct agtcaccttt
    16501 atcagctatt tggatatgct ggtctggcct cttatggcca tcggcttcct ctttaatact
    16561 actcagcgag ggaaggtttc ttaccagcgg attgaaaatc ttttgtctca ggaatctcct
    16621 gtacaagacc ctgagtttcc tctggatggt attgaaaatg ggcgtttgga gtataccatt
    16681 gacagctttg cttttgaaaa tgaggaaaca ctgacggata ttcactttag tttggcaaaa
    16741 gggcaaacac tgggcttggt tgggcagaca ggctctggga aaacgtcctt aatcaagctc
    16801 ctcttgcgtg aatacgatgt ggataagggt gccatttatc taaacggtca cgatattcgg
    16861 gactatcgtc tgacagacct tcgcagtctc atgggctatg ttcctcagga ccagtttctc
    16921 tttgcaactt caatcctaga caatatccgc tttggcaatc ctaacttgcc cctttcagcg
    16981 gtcgaggaag ctactaagct agcccgagtt taccaagata ttgtagacat gcctcaagga
    17041 tttgatacgc tgattggtga aaaaggagtc agtctttctg gtggtcaaaa gcaacggttg
    17101 gctatgagtc gggctatgat tttagaccct gatatcttga ttttggatga ttccttatcc
    17161 gccgtagatg ccaagacaga gtatgcgatt atcgacaacc tcaaggagat gcgaaaggac
    17221 aagacaacca ttatcactgc ccatcgcctc agtgctgttg tccatgcaga ttttatttta
    17281 gttctacaaa atggtcaaat tatcgaacga ggcaggcacg aagacttgct agcgatggct
    17341 ggctggtatg cccaaaccta ccagtctcag cagttggaaa tgaaaggaga agaagatgca
    17401 gaataagcaa gaacagtggg ctgtattgaa gcgcttgatg tcttatctca agtcttatgg
    17461 actcctgacc tttttggcac tcagttttct cctagcgacg acggtcatta aaagtgtcat
    17521 acccctcgtg gcttcccact ttatcgacca gtatctcagc aatcttaacc aactagccgt
    17581 taccgttttg ctggtctact atggtctcta catcctacaa actgtagttc agtatgtcgg
    17641 caatcttctc tttgcgcgcg tgtcttacag tattgttagg gatattcgtc gggatgcctt
    17701 tgccaatatg gagaaactgg gcatgtctta ctttgacaag acgccagcag gttctatcgt
    17761 ttctcgtttg accaacgata ccgagacgat tagtgatatg ttttctggga ttttatctag
    17821 ctttatctca gcagttttca tctttctgac aactctttat accatgttgg tattggattt
    17881 tcgtttgaca gcattagtct tgctctttct ccccttgatt ttccttttgg tcaatctcta
    17941 tcggaaaaaa tcagtgaaaa tcattgagaa aaccagaagt ctcttgtcag atatcaatag
    18001 taagctggca gagaatatcg agggaatcag gattattcag gcctttaatc aagagaagcg
    18061 cctgcaggca gaatttgatg aaatcaacca agaacacttg gtctacgcca accgttctgt
    18121 agccttggat gccctctttt tgagacctgc catgagtttg ctgaaacttc taggctatgc
    18181 agtcttgatg gcctactttg gctaccgtgg tttttctatc gggataacgg tcgggaccat
    18241 gtatgccttt atccagtaca tcaaccgcct ttttgacccc ttgattgagg tgacgcaaaa
    18301 cttttcaact ctgcaaacgg ctatggtttc tgcaggtcgt gtctttgccc tgatagacga
    18361 gaggacctat gaacttcttc aagaaaatgg gcaagccaaa gtccaagaag gcaatatccg
    18421 ttttgaacat gtgtgtttct catatgacgg taaacatccg attctggatg acatttcttt
    18481 ctctgttaat aagggtgaaa ccattgcctt tgtaggtcat acaggttcag ggaaatcgtc
    18541 tattatcaat gtcctcatgc gcttttatga attccagtca gggagagttc tcttggatga
    18601 tgtggatatc agggatttca gtcaagaaga gctgagaaaa aacatcggtt tggtcttgca
    18661 ggaacccttc ctctatcatg ggactattaa gtccaatatc gccatgtacc aagaaatcag
    18721 tgatgagcag gttcaggctg cggcagcctt tgtggatgca gattccttta ttcaagaact
    18781 tcctcagggg tacgactccc ctgtttccga gcgtggttcg agcttctcta ctgggcaacg
    18841 ccagcttctt gcctttgcta gaacagtcgc cagccagcct aaaatcctga ttttggatga
    18901 agcgacagcc aatattgact ctgaaacaga aagcttggtt caagcttctc tggcgaagat
    18961 gagacagggc cgaacaacta ttgctatcgc tcaccgcctt tctactattc aagacgccaa
    19021 ctgcatctat gtcttggata agggacgcat tatcgagagt ggaacccatg aggaactctt
    19081 gactctggga ggaacctatc acaagatgta tagtttgcag gcaggggcca tggcctatac
    19141 tctttgaaaa tctctttaaa ccatgtcagc tttatctgca atctcaaagc tgtactttga
    19201 ttttcattga gtactagaag gaaatccttc aaattacaga tttctttcac cgcattttcc
    19261 attttgtggt ataatgaaaa atgttgacaa atagtataat aaaaacaaag gagaaaccgc
    19321 atgctgaaat gggaagactt gcctgtggaa atgaaatcaa gcgaggttga gttttactac
    19381 cagcttgtct ctaaaaggaa ggggtcgctg attttcaagc gttgcttggc cttggttttg
    19441 gccttggtct tactggttct gacctctccc atctttctca tcttgagcat ttggatcaag
    19501 ttggatagca aggggccagt gatttacaag caagagcgtg tgacccagta caaccgtcgg
    19561 ttcaagattt ggaagttccg taccatggtg atggatgcgg ataaaaaagg aagtctggtg
    19621 acttctgcta acgatagccg cattaccaag gttggaaatt tcatccgacg tgttcgtttg
    19681 gacgaactgc ctcagttggt caatgtcctt aaaggtgaga tgtcctttgt cggtacacga
    19741 cctgaagtgc cacgttatac agagcagtac agccctgaaa tgctggcaac cttgctcttg
    19801 ccagcaggga ttacctctcc agccagcatc aactacaagg atgaggacac catcatcagt
    19861 caaatgacgg agaaaggtct gtcagctgat caggcctatg tggagcatgt tcttcctgaa
    19921 aagatgcgct ataacctcgc ctatctccga gagtttagtt tccttgggga catcaaaatc
    19981 atgtttcaaa ccgtgtttga ggtactaaaa taaagtagtc ataagaaaat gagtacagat
    20041 aaaaggagaa aagcaatgcc aaattacaat attccatttt caccgcctga tatcacagaa
    20101 gcagaaattg ctgaagtagc ggataccctg cgttctggtt ggatcacaac aggtcctaaa
    20161 acaaaagaac tggagcgccg cttgtctctt tacacacaga cacctaagac tgtctgtctc
    20221 aactctgcga cagccgctct ggagttgatt ttacacgttt tggaagtggg acctggtgat
    20281 gaagtcatcg ttccagccat gacctatacc gcttcatgta gtgtcataac tcacgtggga
    20341 gcaactcctg tcatggtgga tatccaagca gatacgcttg agatggacta tgacctgctg
    20401 gagcaagcca tcactgaaaa gacaaaggtg attatcccag tagagcttgc agggattgtt
    20461 tgtgactatg accgtttgtt ccaagttgtg gaaaacaaac gtgacttgtt tgttgcttca
    20521 agcaagtggc aaaaagcctt taaccgtatc gtaattgtct ctgatagtgc ccacgctttg
    20581 ggatctactt ataaaggaca accttctggt tctatcgctg actttacttc cttctcattc
    20641 cacgccgtta agaactttac aacggccgaa ggtggaagtg cgacttggaa ggccaatcca
    20701 gcgattgatg acgaagagat gtacaaggaa ttccaaatcc tttcccttca cgggcaaact
    20761 gaggacgctc ttgccaagat gcaactgggg tcatgggaat acgatatcgt tacaccagcc
    20821 tataagtgca acatgaccga tatcatggct tcacttggtt tggtacaatt ggaccgctat
    20881 ccaagtttgt tgcaacgccg taaggacatt gtggaccgct atgatagtgg ttttgcaggt
    20941 tctcgcatcc atcctttggc acacaagact gaaactgtcg aatcttcacg ccacctctac
    21001 atcacccgtg tagaaggagc aagcctagaa gaacgcaacc tcatcatcca agaattggct
    21061 aaagcaggaa ttgcaagtaa tgttcactac aaaccgcttc ctctcttgac agcctataag
    21121 aatcttggat ttgatatgac gaactatcct aaggcctatg ccttctttga gaatgaaatt
    21181 accctccctc ttcatactaa attaagcgat gaagaagtag actatatcat tgagactttc
    21241 aaaacagttt ctgaaaaagt gctaacttta tcaaaaaaat gacaaactac agtcaagcga
    21301 aagtgatcct gtccctaaaa agtctaattg agtgtaaaaa ctgttgtttt caattgataa
    21361 tagtttacac ctgtagttga ggcctctctc tcctcagaga gagaattttt ataggatttt
    21421 cctttcttgt gggagtcccg tggtttgaaa taagatgtga gcaatttggt gtagcattta
    21481 gaatccttac tagacatcat ttagaaaatc tagtgtcttg ttctagtttt taattcaccc
    21541 tattttttga aagacgtgag tttccatgag tgagattgtg gaaactcgcg tctttttttg
    21601 ttttcagaat attgttcaaa gttttgtgcc tgtctttcat gttctagtca ttcttttgca
    21661 tgatagaatt tatagcatat tgatattata ataatacaaa tattctatat gtttagtgat
    21721 gcttgctata catcattaga tctcccgcga gacaatctat aaaacacttg tctacgatta
    21781 cctatatgcc ctattccagt attttagaag cactgcatct atttttatcg aggttaaatc
    21841 tagcttttat agaaggtcta tttaagaaat atattgtagt gttttagttt caatccgcca
    21901 tatgagcgat attcaggtaa atatccctgg caaatgcttg tatgacaaga tatttgttct
    21961 ttcatttata atttacaaca tatcaacaaa tttaaatata gtaaatggga tattttatat
    22021 tcaagctaag aaagatagca tcacttttga atggaaggct aaagagcaaa ctaggaagtt
    22081 ggccatagat agctcaaaac cctgctttga ggttgtagat atagtaaaat gaaataagaa
    22141 taggacaaat cgatcgggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
    22201 tactattata gtttcagtct actatagaac tgaccaagtc agtaacctag acttagggca
    22261 aggcggcact gacctagttt gaagagattt ccgaagagta taaattttaa tattttcttg
    22321 tgttattcct tgacaattca atttggaaaa tatatgataa agataatgac agcggtgtca
    22381 ttctatctgt tttaagaaaa gtaataatca attgttaaaa atagtaaaaa aattggaggt
    22441 tctgatgaaa tattttgttc ctaatgaggt attcagtatt cgtaaattaa aggtggggac
    22501 ttgctcggta ctattggcaa tttcaatttt gggaagccaa ggtattttat cggatgaagt
    22561 tgttactagt tcttcaccga tggctacaaa agagtcttct aatgcaatta ctaatgattt
    22621 agataattcg ttaagtgtta atagtatcag ctctaatggt actattcgtt ccaattcaca
    22681 attagacaac agaacagttg aatctacagt aacatctact aatgaaaata agagttataa
    22741 ggaagatgtt ataagtgaca gaattatcaa aaaagaattt gaagatactg ctttaagtgt
    22801 aaaagattat ggtgcggtag gtgatgggat tcatgatgat cgacaagcaa ttcaagatgc
    22861 aatagatgct gcagctcaag ggctaggtgg aggaaatgta tattttcctg aaggaactta
    22921 tttagtaaaa gaaattgttt ttttaaaaag tcatacacac ttagaattga atgagaaagc
    22981 tacaattcta aatggtataa atattaagaa tcacccttcc attgttttta tgacaggttt
    23041 atttacggat gatggtgcgc aagtagaatg gggcccaaca gaagatatta gttattctgg
    23101 tggtacgatt gatatgaacg gtgctttgaa tgaagaagga actaaagcaa aaaatctacc
    23161 acttataaat tcttcaggtg catttgctat tgggaattca aataacgtaa ctataaaaaa
    23221 tgtaacattc aaggatagtt atcaagggca tgctattcaa attgcaggtt cgaaaaatgt
    23281 attagttgat aattctcgtt ttcttgggca agccttaccc aaaacgatga aggatgggca
    23341 aatcataagt aaggagagca ttcagattga accattaact agaaaaggtt ttccttatgc
    23401 cttgaatgat gatgggaaaa aatctgaaaa tgtgactatt caaaattcct attttggcaa
    23461 aagtgataaa tctggggaat tagtaacagc aattggcaca cactatcaaa cattgtcgac
    23521 acagaacccc tctaatatta aaattttaaa taatcatttt gacaacatga tgtatgcagg
    23581 tgtacgtttt acaggattca ctgatgtatt aatcaaagga aatcgctttg ataagaaagt
    23641 taaaggagag agtgtacatt atcgagaaag cggagcagct ttagtaaatg cttatagcta
    23701 taaaaacact aaagacctat tagatttaaa taaacaggtg gttatcgcag aaaatatatt
    23761 taatattgcc gatcctaaaa caaaagcgat acgagttgca aaagatagtg cagaatattt
    23821 aggaaaagta tcagatatta ctgtaacaaa aaatgtaatt aataataatt ctaaggaaac
    23881 agaacaacca aatattgaat tattacgagt tagtgataat ttagtagtct cagagaatag
    23941 tatattcggg ggtaaagaag gaattgttat tgaggattca aagggtaaaa taaccgtttt
    24001 aaataaccaa ttttataatt tatccggtaa gtatatatca ttcatcaaat ctaatgcaaa
    24061 tgggaaagaa cctgttatac gtgatagcga tggtaatttc aatattgtaa cggagaatgg
    24121 gctttacaaa attgtaacaa ataatttaag tgataaaaac gaaaaagaaa aaaacaaaga
    24181 ggaaaaacaa tctaattcaa ataatgtaat tgatagtaac cagaagaaca gagagtttaa
    24241 ctcaagtaaa gataatagac aaatgaatga caagatcgac aataaacaag ataataagac
    24301 agaagaagta aactataaaa tagttggaga tggcagagaa actgaaaatc atattaataa
    24361 atctaaagaa atagtagatg taaaacaaaa attaccaaag actggttcga acaagattat
    24421 ggaactattc ttaacagtga caggaattgg tttacttttg acactaaaag ggttgaagta
    24481 ttatggtaaa gataaataaa atttgttcga tacaaggaag ttccgtagaa aatgaggata
    24541 ttgtaggttc acaaaatcag tatttttgga ttattggtgg agctacagat ttatataatt
    24601 ctaaagagga gataggttat tcagtctcag aagttgtaca tattttatca gaaagtttgt
    24661 cggttaattg taaagaatca aaaactctta aacaaatatt tgaaactgct ttactcgagg
    24721 ttaaagatga aatcggttta aactcatatg aattaacaga gtatagtaaa atgaaataat
    24781 aataggacaa atcaatcagg acagtcaaat cgatttctaa caatgtttta gaagtagatg
    24841 tgtactattc tagtttcaat atactatatt atcgcttacc aatatttgct aaactttcag
    24901 aaaaaagttg gagtatatga tgctaggtga ctgcgtcatg ttagtaaacg aaatggaaat
    24961 aactgatcat agagtagata acttatttga aaaagggaaa aatgagataa aagatccatg
    25021 tagtagattt agcaatagga catataaaag ctttagaaaa agtatctgaa aaaacagatg
    25081 tttatatcta taacctaggc tcgggagaag gcactagtgt attacaactt gtaaatacat
    25141 ttgaaagtgt taataagatc cctattcctt ataaaatagt tccaagacgt tcaggagacg
    25201 ttgcaacttg ttatgcaaat gcagacaaag catataagga attaaattgg aggacaacaa
    25261 aatcgattga agacatgtgt agagatacat ggaattggca atcaaaaaat cccaatgact
    25321 ataattgatg atactgtcta tatgagtgct gtattttgga aaaattactt aaccttttaa
    25381 tgaaatgcat atttaatgaa agataaataa aaaaagtttg acagcgcttg acaaaggaaa
    25441 cggtttcatt gtataatgta aacatggtga caccgatgtc aaatataaaa aagaaggtct
    25501 ttatatgaaa aacttaacaa aaattaagtt caaagaaaat ggggaattta atcatttccc
    25561 tgggaataca gttgtagcaa atctttatac taaacaagat ttgatggaag ttgttgatat
    25621 tattcaatca cgttatagag aattaccatt tatcgataag tttactttaa ctccaaggaa
    25681 ttctattcac atgactgtaa ttgaattgtt gtgccatgaa aatcgtgaaa cggagttttg
    25741 gagcagtaat cttcctctag atacaccttt acaggaaata catgattact ttgctaaaca
    25801 acttgaaatt tttccattgt tggatgaaga aattcatatg cgtataactg aaatgggaaa
    25861 acaaaacata ctagttgaac ctgcagatga agcttctgca aagagattag aagaaattcg
    25921 tacttatgtc tcagaaaaag caggtgtttg tttccctaat catgatagat atcaattcca
    25981 tatttcaatt gggtatcttc ggattcctct aaccgaagag gaggaagaag agtttactaa
    26041 agtcagagca gaattaactg aaattttatt agagaagatt ccaattatta ctgtaaaccg
    26101 tattgactat actgtatttg aagatatgag acaatttgtt ccatatcacg aaaaatttaa
    26161 ataaaataat aaaaaaggag aacttatcat gaaaaaaatg aaagtttggt ctactgtact
    26221 tgcaacggga gttgctctta ctacacttgc tgcttgctct ggaggttcaa attctacgac
    26281 tgcttcttca tctgaagaaa aagctgataa aagtcaagaa ttagtaatct attcgaactc
    26341 agtctcaaat ggtcgtggtg attggttaac tgctaaagca aaagaagctg gttttaatat
    26401 aaaaatggtt gatattgctg gcgctcaatt agcagaccgt gttattgctg agaagaataa
    26461 tgcagttgca gatatggtat ttggaattgg tgctgttgac tcaaataaaa ttagagatca
    26521 aaaattacta gtacagtaca agcctaaatg gttagataaa attgatcaat ctttatcaga
    26581 taaagataat tattataacc cagttattgt tcaacccttg gtattgattg gagctcctga
    26641 tgcaaaagaa atgccaaaag actggacaga gttagctagt aaatataagg gacaatattc
    26701 catttatggc ttaactggtg ggactggacg cgccatttac gcaagtattc tagttcgtta
    26761 tcttgatgaa aaaggtgatt taggagtatc ggaaaagggc tgggaagttg caaaagaata
    26821 ctttgcaaat gcctatacac tacaaaaagg tgaaagcaca gttgttaaag tattagacaa
    26881 agaaaacgct atccaatacg gtatgatctg gggttctgga gcgttagtcg gacaaaaaga
    26941 acaaaatgtt gtttttaaag tgatgtctcc tgaaattggg gttccatttg taactgagca
    27001 aacaatgatt ttgagtacaa gtaagaagca agcattggct aaagaattta ttgattggtt
    27061 tggtcaatct gaaattcaag tagagtacag taaaaacttt ggctctatcc ctgccaataa
    27121 agatgccctc aaagagctac cagaagatac taagaaattt gttgatcaag tgaaaccaca
    27181 aaatattgac tgggaagctg ttggaaagca tttggatgaa tgggtagaaa aagctgaatt
    27241 agaatacgta caataagaaa taagagttat tatttatgtc caagtctctc tattatttct
    27301 aaatttatgg aagaaataaa gagaggcttt tggtttagta atagagggag ttagtgagat
    27361 gattaaattt gataatattc aaattaaata tggtgatttt gttgcaattg ataatctgaa
    27421 tttagatata catgaagggg aattctttac atttcttggg ccttcaggat gtggtaaatc
    27481 aactactttg agagcattag taggtttttt agatccatca tcaggaagta ttgaagttaa
    27541 tggaacagat gtcactcatt tggaacctga aaagcgtgga attggtattg tatttcaatc
    27601 ttatgcgcta tttccaacta tgactgtttt tgataatatt gcatttggtt taaaagttaa
    27661 gaaggtagct ccagatgtta ttaaagctaa agtatcagca gtggcagcaa aaattaagat
    27721 ctctgatcaa cagttacagc gtaatgtatc agaattatct gggggtcaac aacaaagggt
    27781 agcattggct cgtgctctgg ttcttgaacc taaaattctt tgtctagatg aaccattgtc
    27841 aaaccttgac gcaaaattac gtgtagattt gagaaaagag ttgaaaagac ttcaaaaaga
    27901 gttaggtatt actactttat atgttactca tgatcaagag gaagccttga ctttatctga
    27961 tagaattgca gtctttaaca atggatacat cgaacaggtc ggtacaccag tagagattta
    28021 tcataattct caaactgaat ttgtatgtga ttttattgga gatattaatg ttttgaccga
    28081 tgaaacagtc cacgaagtat tattgaaaaa tacaagcgtt ttcttagagg ataaaaaagg
    28141 atacattcga ttagagaaag ttcgattcaa tcgtgaaact gaacaagatt ttattctaaa
    28201 agggacaatt attgatgttg agttttctgg agttacaatt cactatacaa taaaagtttc
    28261 tgaaagtcag attcttaatg taacaagtat tgatagtcag gctgctatta gatctgtcgg
    28321 agaaagtgtg gaattattta tcacaccatc agacgttctg caattttaag gaggtgcagt
    28381 atgcgtcata aattaaattt aaaagattgg cttattcgtt tagggttaat ctggttctta
    28441 gtaacattta ttatttatcc aaactttgat ctagtagtga atgtatttgt aaaaggagga
    28501 gaattttccc ttgatgctgt acatcgtgtt ctaaaatctc agagggcact tcagagtatt
    28561 atgaacagtt ttaagttagc attttcactt attattacag ttaatgtcgt aggtattctt
    28621 tgtgttctat ttacagagta ctttgatatt aaaggtgcta aaattttaaa attaggttat
    28681 atgacctctt taatttatgg aggagtggtt ttagcgactg gatataaatt tgtctatggt
    28741 ccttatggat tgattacaaa atttttacaa aatgttatcc cttctttaga ctctaactgg
    28801 tttattgggt atggtgcagt cttattcatt atgacatttt caggaactgc taatcataca
    28861 ttgtttttaa caaatacaat tcgaagcgtt gactatcaca ctattgaggc tgctcgaaat
    28921 atgggagcaa aaccatttac tgttttccga aaagtagtgt taccaacctt aattccaact
    28981 ctatttgcac ttactattat ggtttttctt agtggtttat ctgcagtagc agcacccatg
    29041 attgttggtg gtaaagaatt tcaaactata aatccaatga ttattacatt tgcagggatg
    29101 gggaattctc gtgatttagc tgccttactt gcaattattt taggtattgc aactacaatt
    29161 ttgcttacta tcatgaataa gatagaaaaa ggtggaaatt atatttctat ctctaagact
    29221 aaagcgcctc taaaaaaaca aaaaattgcg tctaagcc
//
LOCUS       DAVHSI010000024        29054 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.024, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000024 DAVHSI010000000
VERSION     DAVHSI010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.024"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..551
                     /locus_tag="VVR21_001267"
     CDS             <1..551
                     /locus_tag="VVR21_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU6055152.1"
                     /translation="KCDGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSP
                     VLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYRHDSYHRFL
                     ESKGIQASMSRKGNSQDNGRMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYN
                     NKRIKVKLKGLSPVQYRTKSFE"
     gene            complement(679..1701)
                     /gene="cbpF"
                     /locus_tag="VVR21_001268"
                     /pseudo
     CDS             complement(679..1701)
                     /gene="cbpF"
                     /locus_tag="VVR21_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(1720..2545)
                     /gene="cbpG"
                     /locus_tag="VVR21_001269"
                     /pseudo
     CDS             complement(1720..2545)
                     /gene="cbpG"
                     /locus_tag="VVR21_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(2626..2865)
                     /locus_tag="VVR21_001270"
     CDS             complement(2626..2865)
                     /locus_tag="VVR21_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055153.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3015..3281)
                     /locus_tag="VVR21_001271"
                     /pseudo
     CDS             complement(3015..3281)
                     /locus_tag="VVR21_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3306..3617)
                     /locus_tag="VVR21_001272"
     CDS             complement(3306..3617)
                     /locus_tag="VVR21_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU6055154.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(3542..3773)
                     /locus_tag="VVR21_001273"
                     /pseudo
     CDS             complement(3542..3773)
                     /locus_tag="VVR21_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3774..4406)
                     /locus_tag="VVR21_001274"
     CDS             complement(3774..4406)
                     /locus_tag="VVR21_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055155.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(4420..5415)
                     /locus_tag="VVR21_001275"
     CDS             complement(4420..5415)
                     /locus_tag="VVR21_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6055156.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSLTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5412..6110)
                     /locus_tag="VVR21_001276"
     CDS             complement(5412..6110)
                     /locus_tag="VVR21_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU6055157.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EIVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6188..7198)
                     /locus_tag="VVR21_001277"
     CDS             complement(6188..7198)
                     /locus_tag="VVR21_001277"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU6055158.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7182..8189)
                     /locus_tag="VVR21_001278"
     CDS             complement(7182..8189)
                     /locus_tag="VVR21_001278"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU6055159.1"
                     /translation="MIAVKTCGKLYLAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDVYTPLLRQ
                     LKEASQDLQTVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8176..9129)
                     /gene="mvaD"
                     /locus_tag="VVR21_001279"
     CDS             complement(8176..9129)
                     /gene="mvaD"
                     /locus_tag="VVR21_001279"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU6055160.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(9111..9989)
                     /gene="mvk"
                     /locus_tag="VVR21_001280"
     CDS             complement(9111..9989)
                     /gene="mvk"
                     /locus_tag="VVR21_001280"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU6055161.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10111..10440)
                     /locus_tag="VVR21_001281"
     CDS             complement(10111..10440)
                     /locus_tag="VVR21_001281"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055162.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYFVN
                     YNGEWVQ"
     gene            11103..11441
                     /locus_tag="VVR21_001282"
     CDS             11103..11441
                     /locus_tag="VVR21_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEU6055163.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            11341..11811
                     /locus_tag="VVR21_001283"
     CDS             11341..11811
                     /locus_tag="VVR21_001283"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055164.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            11970..13202
                     /locus_tag="VVR21_001284"
     CDS             11970..13202
                     /locus_tag="VVR21_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6055165.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLASIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(13320..14276)
                     /gene="cbpC"
                     /locus_tag="VVR21_001285"
     CDS             complement(13320..14276)
                     /gene="cbpC"
                     /locus_tag="VVR21_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU6055166.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLNTSN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYYVNYNGEWVR"
     gene            complement(14374..15063)
                     /locus_tag="VVR21_001286"
     CDS             complement(14374..15063)
                     /locus_tag="VVR21_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055167.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(15075..16499)
                     /gene="gndA"
                     /locus_tag="VVR21_001287"
     CDS             complement(15075..16499)
                     /gene="gndA"
                     /locus_tag="VVR21_001287"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU6055168.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFAYIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(16575..17969)
                     /gene="mapZ"
                     /locus_tag="VVR21_001288"
     CDS             complement(16575..17969)
                     /gene="mapZ"
                     /locus_tag="VVR21_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU6055169.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(17981..19138)
                     /locus_tag="VVR21_001289"
     CDS             complement(17981..19138)
                     /locus_tag="VVR21_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU6055170.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(19223..19603)
                     /gene="rnpB"
                     /locus_tag="VVR21_001290"
     ncRNA           complement(19223..19603)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VVR21_001290"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(19624..19953)
                     /gene="gpsB"
                     /locus_tag="VVR21_001291"
     CDS             complement(19624..19953)
                     /gene="gpsB"
                     /locus_tag="VVR21_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU6055171.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(20023..20550)
                     /locus_tag="VVR21_001292"
     CDS             complement(20023..20550)
                     /locus_tag="VVR21_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU6055172.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            20616..21212
                     /gene="recU"
                     /locus_tag="VVR21_001293"
     CDS             20616..21212
                     /gene="recU"
                     /locus_tag="VVR21_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU6055173.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            21209..23368
                     /locus_tag="VVR21_001294"
     CDS             21209..23368
                     /locus_tag="VVR21_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEU6055174.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(23535..28838)
                     /locus_tag="VVR21_001295"
     CDS             complement(23535..28838)
                     /locus_tag="VVR21_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6055175.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVEEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVVAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLPTDKEKMYYFNTQTGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKVQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
BASE COUNT         8401 a         6622 c         5206 g         8825 t
ORIGIN      
        1 taaaatgtga cggcaagaag gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa
       61 caatggaaaa gtgctacaca gatgtgacag aatttgccat tccagcaagt actcaaaagc
      121 tttacttatc accagtttta gatggcttta atagcgaaat tatcgcctat aatctttcaa
      181 cttcacccaa cttagaacaa gtacaaacaa tgttggaaca ggcattcaca gaaaagcact
      241 atgagaatac gattctccat agtgaccaag gctggcaata ccgacacgat tcttatcatc
      301 ggttcctaga gagtaaggga attcaagcat ctatgtcacg caagggaaac agccaagaca
      361 acggtaggat ggaatctttc tttgggattc tgaaatcgga aatgttttac ggttatgaga
      421 agtcgtttca gtcgcttaag caattggaac aagctattgt agactatatt gattactaca
      481 acaacaagag aattaaggta aaactaaaag gacttagtcc tgtgcagtac agaactaaat
      541 cctttgaata aattatttgt ctaacttttt gggggcagta cattgttaac ttgatactat
      601 gcgttttttg attgtgaaga cttttatcca cctattatac aaagtcaagt atccatcaca
      661 gtttacaatt agccttcatt acttaaccca ttcaccatta tagtttaagt agtaaccacc
      721 tactgtggta ttaacagcta aagcacctga atcataggca tagtaccagt taccattgac
      781 ttggaaccag cctgttttca tatctccatt acttgcattt agatagtacc aagtcgaacc
      841 ttcctgatac caaccagttg ccatagctcc tgatgaacgg agatagtacc atttgttccc
      901 aaggttttgc caaccagttt tcatatcgcc attttcagca tctaaatagt accaagttga
      961 accatcttga taccagccag ttgccatagc tcctgatgaa cggagatagt accatttatt
     1021 accaagatgt tgccaacctg tttgcatgat gccagttgct ggatctaggt agtaccatgg
     1081 agcaggtttg agcttctctt catcataggt aagagggtaa tccttaaccc aaccacgtgc
     1141 tagctctcca accgtcaatc tgttgatgcg agaatcaaag ccaccatcct tctgcaaata
     1201 ataccagtcc ccatcatcat aaacccaacc agtttttaaa gtatgataac tacgctgatc
     1261 ttcaaaataa tagattcgtt tctctgctgg gctatcatat tcttccccat gatgtttgtt
     1321 ggtatttgta gcagtttttg cttctaaaac ttgcttgcca acaaattatt gtaatacacc
     1381 atcttgacca aaataaaacc aatctggtct aagagcaatc tctattcttg gagaaggacc
     1441 aatcgtaacc cccttgtgtg gagcaggtat atattgccag ccgacaacca tctctccgga
     1501 taaaggatca aaataatagt atttcccatc tatcactctc cagtaggttt cttttagatc
     1561 cccctttttg tagtaggttc taccattttc ttggacaaac tgccatcctt cagaatcatc
     1621 tgcaaatact gtactggtcc ctagcaaacc gaagaaaaat gtggctagta cgacttgcat
     1681 cattttttta aaaagcttca ttttatatat cctccaacat caaatccact caccagatga
     1741 agcgaagtta taaactttac catcgatagt ttggctacct gtaaccattg ctctatttga
     1801 attgagataa taccattttc catttacttt ttgccaatct gtaagcatct taccggaact
     1861 gtctaaataa taccaagtat catttatctc ctgccaaccc gtttgtttat catgttgtct
     1921 ataatagtac caactaccat ttattttctt ccatccttca agagagtaac ctttaagaac
     1981 cgaataaata aataaatggc aaatttcgtt catttaattt aactgcactg ttaatttgat
     2041 tagctccatc tcctaaagta tgcactccta ctacgcggtg actagcatca taaactgcag
     2101 atccactaga cccctctaaa gtatcaactt ggtaatccaa gaacatgcca tcatcactta
     2161 aaacttgttt tttatctgta tacatttgat gaattttaaa attatatgat agatagcctg
     2221 tgatagtcac agttattcct gtcaaatttt tttgactagt aggaagaccc aaagtcccta
     2281 attttgcacc aatgggctct tctagaatta ataaagccaa gtcatattcc cttgcattct
     2341 tagaatttaa atttctaaat tccttcaaat aacgaacttc ctttactttg atctttccaa
     2401 atagttcttg acttggacta acagccggaa gaacataaat atcatccgct tctttcccat
     2461 agtcatgtct gtagtagttg tgagccgctg taattaacac attatcttta ataaaattcg
     2521 cacttcccct cccttctaca ttcattccat cggctactcc ataatactta gataaaacca
     2581 tagctgaagt cgaatacgga tactgtaaag tattatcaat tttaatcaaa tcatcattac
     2641 cgataatact tctgattgct tttggtagta tgaaccatac gttggtgaaa tctcagataa
     2701 tgaagaatca ttagactctg gacctttttc tagtgtctca cttacctcat attcttcacc
     2761 tgtactagaa ataacactca aagcagatac tgtcgataac tggctagcca ataaagtact
     2821 cgcaataatt gaaataccca attttttata aacagttttc ttcattatcg tatcctccta
     2881 atgtaattat agcgtactat tctaaatttc tcaatctact atagaatcaa gaaatctacc
     2941 accttcttta aataccctcc attatcacat aaacaggtaa acttttcaat taatgactgc
     3001 gcttttcaat cacgctagag gtacttgctt gcttctttga tactaagttc agccattctt
     3061 tccttgtttt tctcaataaa gcatgttacc caagtgggat tcgttttgga gtagtctcgc
     3121 agagtccagc caatggcttt attgataaaa aattctgttt ggttcaagtt atgaaggaga
     3181 atcttttcca ttaattgagt attggtcttc tcttttctta acaactggtg gtcaatagcg
     3241 acacgtctca gccagatatt atctgatagg ctccatttta tactcaatga aaatcaaaga
     3301 gcaaactagg aagctagccg cagattgctc aaaacactgt tttgaggttg cagatagagc
     3361 tgacgtggtt tgaagagatt ttcgaagaat attaagatta tttcttctag ttcagggtgt
     3421 ttatacacca aactccctac tactcgatct aggatatcta ccgtgtccca ccaggatttt
     3481 gtcacgacta actgctctag cttaggcaaa tcggtttcct ttagataaga ctgcattgct
     3541 ttcaaatagt tagcagccac atattggtat tttctaggct ccttttccca gcaagtgtct
     3601 gcaaaatccc aatcgataat ctttgttttt ttcgcttctg gaaaatattt ttatagagtt
     3661 tatttctttc aacctagaaa agaaaattga tggcgcatat aggcttccat gggccttgct
     3721 tttttagagt cttttgctgc ttctagctcc tcaagtaaat ctgctaaacc catctaaaac
     3781 tcctcttgcc ccaccaaatg gtgctgaaag gcgtagacag ccgcctgggt acgatcactg
     3841 acttcaagtt tggcaagaat gttggacacg tgggtcttga ccgtcttgag agagataaag
     3901 aggtcatctg cgatgcgctg attttcgtag cccttggcga tgagttggag aacatctcgc
     3961 tcacgcgcag tcaattcttc atgaagttcc atatgattgc ggtggtattc aaccttcttg
     4021 ctaacctctt gctcaatggc cagctcgcca gcagctacct tactgacggc atgaagcaat
     4081 tcatctgcac tagaagtctt gagcatatag cctttggcac cagcatctaa gactggcatg
     4141 attttttcat tgtccagata agaggtcaca atcaaaatct tggcttcagg ccattcttta
     4201 aggattgcta aggtcgcgtc aatcccattc atctcaggca tgacaatatc catgacaatg
     4261 acatctggac gcagttccaa ggccaagtca atcccttgag acccgttgga cgcctcaccc
     4321 acaacttcta catcgtcttg gaggtcaaag tagcttttca agcccaatcg gaccatttca
     4381 tggtcatcta ctagtaaaat tttcatcttt actcctttat cattccttat ctaacagggg
     4441 aatacggata tcaaccgcca gcccttgctt gggagctgtc aagagttgaa ctgttccagc
     4501 catatcttca acccgctcct tgatatttcg cagtccataa ctcaagtcgt ctaagctccc
     4561 taactggaaa ccaatcccat tgtccaccac cttcagttgc aattcaacat ctgtctgata
     4621 gaggtagaca tctaggcaag atgcctgggc atggcggagc gtattgctaa tcaactcttg
     4681 caggatacgg aagatatgct cctcgatttt cttaggcaat ttcgtcatat tctgcttgag
     4741 actaacccta agatcactct tgtcctcaag ctcttttaag agaatttgaa tcccttctat
     4801 caagctcttc tgctccagtt caactggtcg caaatgcaag agcaaaaccc gcaaatcctt
     4861 ctgggcagtt tctaaaatag ctgtgacact ctgcaactgg atctgcatct tttctctatc
     4921 taatttcaaa gcctgctgac tgatacccga taaaatcatg tgggccgcaa acaactcctg
     4981 actgactgta tcgtgcaaat cccgagcaat tcgcttccgt tctttctcga tgatttcctc
     5041 ttcctgagca aggctatgat tttcagcttt ttgaagagct tctgtcaaaa ggttaagttt
     5101 acctgataag gacttgaaac tggcatccaa atctggatct acaacctgaa ctacttcttg
     5161 ccctgccaat aaacgcttga gattggcctg catttttctt agagaaagct cttcgatccc
     5221 tcgccaaaac agggctaaga gacaggtcag ggacatgctg aaaaccaaca ataaaaagac
     5281 aaatttttct gttttttcga catcgtgcaa aaagatagac cagtcaaaat caagtatttc
     5341 cagcaagcta tgggagaaaa aaaagacaaa caggaaggag gtgagagcga taatgacata
     5401 ggcttgtttt ttcatcctct aaccacctcc acatcaccaa tcatagtggt caagaaaatc
     5461 ttgacactct tgttactctt gagatagtct tttgtttctt gatgatagtg ttcattgcgg
     5521 agggctcgct tgggctggtt gaaaaaagtc aaatccccat agagacagtt aacgctgaga
     5581 ctgacttcca catctacagg tacgatgatt ttggtcgttc ctaccatctt tctgaggata
     5641 atgacattgt catgattggt taagatgacc ctctccagat gaatagtgtc cttgcccatg
     5701 aagcgaaaga gattgatatc atcgaattgg caagtctggt agcttgaaaa atgatgaaga
     5761 tttccaaacc aacgattttt ctccttctta accgtcacga tctcttcaaa aaccaaattg
     5821 gtctgctctt tttcctggtt catcatcggg taaagaagaa agaggctata gataaccgca
     5881 acaaaaatag ctagaatcac aaaaggattg agcataacga tgaaaaagaa gagaatggtt
     5941 accgctacta aaagaagatt atttccctct ttaccagtgt agtagcgaat caaaagcaaa
     6001 aagaggaata gtatcagcag aaaacgcgaa aaatgctctg ataccatcaa aatcagagct
     6061 cctgtcagaa gacaggcttc gataaataaa aagattttaa attttctcat aggttcatcc
     6121 tctcccttct attttatcac aattcaaaaa agtcacctca gtctgaggat ggaaaaaaag
     6181 gcgctggtta cgcctttttc atctgatcat ttgcttcttt taattttcca taaagaagat
     6241 agtctacttt ttgtagatct gctatggtgg cacagttaag ggaacacata atcaagcgta
     6301 gatctgcttt ccagccttga acaatgccaa tcacttcttc aactgtgtag gtttcaacca
     6361 attccagaac ggttcgtgac aatcccacag ccttagcacc aaaaaccaag cacttaatca
     6421 tatccagcgg attccgaacc cctccactaa ccaagagttc gaccttatct ttccattctt
     6481 gggcattgag aagggcctgc atggtagact gaccccattg attgaggtaa tcacgctggc
     6541 cactacgacg gttttcgata taggcaaagc tggtgccacc acgacccgat aggtccactg
     6601 tacgaacacc gaattcatag gctctttcga ttgtcttggc atccattcca aagcccactt
     6661 ccttgaggac aataggaacg ggaatttgct tgctataatc tgctagatgc gattgccagc
     6721 ttctaaactt cctttctccc tcgggcatga gtaattcctg catgacattg acatgcactt
     6781 gcaatagaac aggattcatc tcttctacag tctgaagccc taactcgaca ggcttgtcca
     6841 atccaatatt ggttccaagg aggagattgg gatgactaga cttgacagaa aaagaatcat
     6901 ccgttggatt tttgagggct gcgctataag aacccgttac aaataaaata ccacaggatt
     6961 ccgccacctg agccagcttt tgattgattt ctcttccctt attacttcca ccagtcatgg
     7021 cattgatata aaaaggaaag tcccactttc gaccagcaaa ctctgtcgaa agatcgattt
     7081 catccagatt gtaaagaggc aaggaagaat gaatcagctc cacctcatca aagctattat
     7141 aggaactttt ctgctcaagg gcatagagga tatgctcgtc cttacgattt gtcgtcatgt
     7201 cctatccttt cttgatataa gagctcaatc cccagatcgg cccaacgatt ttttaaggtt
     7261 tcggttgatt gcgcatcaaa actcagggcg atgccacagt caccaccacc agcaccacta
     7321 ctcttggcaa cggtctgcaa atcttgactg gcttctttca actgtctaag caaaggcgtg
     7381 taaacatctg tactcaagcc ttctaaaagc ttgctggcta cttctacttg ctcgataact
     7441 ttttcggctt tcccctgctc caaggcttcg accaaagaaa ccaccgtttc ttttgaggaa
     7501 gttaaaaaat tttgattgat attttgcttg atttgctgga ccatgtgact cgatacagcc
     7561 acttccttgg tccatcccac taagaaatca cattctaaag ttggtttcac ttgtgagata
     7621 aaaaatcccc aatcacgctc cagaactgtc gccaagtttt cttcttctaa ccaagcagcc
     7681 accttctggc gatcaaatga ctggtagaga accaaatcct ctgccacaat acaggcaagg
     7741 tcgcccatgg aaccattgtc tcctcgcttg agcaagacag cgctagtcag cttgaacaag
     7801 agattctgat caaccgaaag attatagaga gccagtaaag ccttgacaac caagacaacg
     7861 acgctgccac tagaacctag accaaacttt ttcccttctc gttccatttt gccacagatt
     7921 tctagagaaa aaggtcttaa attctgacca cgaacagcga ggaagtctcc catcaaagca
     7981 atcgtttctt gaatcaagct atagtcagga ttgggcctta agtccactgc gaaatcaaac
     8041 atatctgaat agatacggta gctatcagaa aaagcaatct cagccctcat atagatggga
     8101 atatccttta tcaaagctaa ctgccctggc tctaaaatag catattcacc tgccaaatag
     8161 agttttccgc aagttttaac agcaatcatc ttgactcaaa tcctttgttt ttgacacaat
     8221 caagcgataa cgctgaccga aaatttctga taaatgctcc aagtctttct cctgacagaa
     8281 gaccttaaca ttgggaccag catccatggt aaagtagcag gcctctcctt tctcacgaag
     8341 ctggcgaaca aagtccatag cctcataaga ggcatccgtc agataagaaa aggctggact
     8401 agcagtcttt gtcgtagcat gcatagccag ggcatttttc tccgttaatt ctccaatctt
     8461 ggcaaaatca ttttccttga gataaatcag catatcctga tagtccttct cagactgacg
     8521 aacccagtcg tcaaaagtcg tcgaggtttc cacacaaagt ttcatcccgt cacggctaga
     8581 gattggtttt ttcttgtcct ctagcaccaa cataatcata gctagtttca agtctgtctc
     8641 tacagggtaa atttctccac tatccttatc ccaggctcct agtggtccat aaaaactccg
     8701 agaagaagag cctgaggcaa atttggcttc ctgtgccaac tgacttctat ccaatccaag
     8761 cttgaaataa gcattacaag ccttgaccag ggcggacaaa ccactagaac ttgaggacag
     8821 gcccgctgca gtaggcatat tgttttgagt atcgatacgg acaaagccct caccagctgg
     8881 acgataacgg tcaataatct tactcatctt agcatgctcg acctcatttt gtagctgacc
     8941 attgatgtaa aattcgtcag ctgttacatt ggctggtaaa ggcgacaagg tcgtctctgt
     9001 atacatattt tccaaagtta gagaaatact gctagtagca ggcaccatct ctttttcttt
     9061 tttctttccc caatatttga taatagcaat atttgcgtag gaacgtactg ttacaggctc
     9121 tctatccatg tctgaacagc tcctttctct tctaatcttt ctgctagttc ttgtgcgtgt
     9181 gtcaaattgg ttaccaaggc tatgatacaa cctcctagcc caccaccgct catcttggca
     9241 cccagagcac catggctaag agtcgtttca accaaaaagt ctgcctcagg gctactgact
     9301 ccaatttctt ttaaatgtaa atgcgcttga ctgaggattt gtcccagtcc ttcagcatct
     9361 ttttgtgaaa tcgcaacttc tgcttgctgg gttaattctc ccaaggcatg caaaaacggt
     9421 agggcatcct tgcccttatt ttgaaccact tggatggctt cacgagtatg accataaaca
     9481 cccgtatcgg caatcaccaa ataggcggat aaatccatct caagttctgt aaatcctacg
     9541 ttcttgataa agcgaatagg ttggtcactg agacaggtct tagcatccaa accactagga
     9601 ttcatatggg caatcatttc agctcgattg accaagattt ctagtacatc atgaggcaga
     9661 tcagcctgat agtagtcaaa taccgcacga atggccgcta tgctgatagc cgctgacgaa
     9721 cccatccccc gtttctcagg gatagccgag tcaatctcac aacgaatgca ggcttctgtg
     9781 atatccaaat actccagtga ggcataaacc gccatggaca aggtatcctc ctcataaagg
     9841 cgccaaggac tctctgcagg aactacctta caggtcacct ccacctccaa aagaggcagg
     9901 gaaatggcag gataaccgta aacgaccgca tgttccccta ttaaaattat cttactatgt
     9961 gcctgaccga caccaacttt ttttgtcatt ttttcctttt actagacgaa aaaacgtctt
    10021 atttttcata caagtattaa ttctttccta tctattttat tatattttca caaaaaaagc
    10081 gattgtttcc attcacaatc gcttctttca ttattgaacc cattcgccat tataattgac
    10141 aaaatagcca tctacggtcg tattcactgc caaggcacct gagctataag cgtagtacca
    10201 tctgccattg acctggaacc aacctgtcgt catagaacga cgaaagaaac tccataccgt
    10261 taagtaaaga ggaaagtcgt gagggatcat gcgccattga caacctgttt tagtgacgta
    10321 caaagtctca ttaacaagta ctcgtttcgg ccatttatag gtgcggtgtt tggagaaata
    10381 gggttcaatc ttagcccatt cttgatcgtt taaatcagta tcatatgctt tgcgtgtcat
    10441 aactctagtt taacattttt tgtgaataca agttctaaat aatcgaccac gaaaatttct
    10501 taagtggaaa acgccttatg aagtatgcta cgggaaactt atgcacttaa tttgacaatt
    10561 caagatgtaa aaatatatac tatagtagat tgaaactaga atagtacacc tctacttcta
    10621 aaacattttt agaaatcgat ttgactgtcc tgatcgattt gtcctgttat tatttcattt
    10681 tactataata tttgataagt tatcctaaaa gtgttattat gttgttgtgt tatagattga
    10741 ttgaatctaa ctaaaggatc ctattcaatt actagaacta tcacatactc aaggtcagct
    10801 cacagatgag caactatttt ggttacaatg tctactaaat ttaagtcaaa caaataattt
    10861 agtcaaaatt aaaaaaaata gaggaacata aatatgatta caaaacagaa tgtaatagtg
    10921 ttctacgatt tttactagat aaaactgtaa attctgaagg aaggatcact tcttcaacag
    10981 aatttggaaa tttcgtaagt aatttatcat tccaacacgg aatagctgga ctactgtttc
    11041 ctctaaataa attgtacccc ccagaactgg attctaaaat actctctatc atcaagaagg
    11101 cagtgacaat tagaacgaca cacacatatg aatatcaata ctcactgcta tttggtgatg
    11161 caggctatct atggttactc ctacatttat tttctatcag taaaaatcaa tactatctac
    11221 aattagcaaa cgtcaccgct aagaaattaa tagagaatta tgatactcta gaggaaatag
    11281 actttgcatt gggaaaatct ggtgtcctat tatcattaat aaaatactat caatttacca
    11341 atgacaatac tcttaaaact ttcatccaca atagtatatg gggaaattta tcattatttc
    11401 ctacaaagag atacagccaa agaaagcatt ttagactata gctttgctca tggatattgt
    11461 gaaattgcat atgctttatt tgcctattct aaagtcttag aaccttctat gttctataat
    11521 gatctccata cattccatgc tgaattaaaa aaattattag aaaaagttac ttctaatact
    11581 gaaaatttag gaaatttaca actttcttgg tgcgaaggaa tttccggaat aatcttatat
    11641 ctttgtatgt acgattgtga cggaaacaaa gatattatta gtaaatatca agaatttgtt
    11701 tttaaccatc atctaaaaat gatgacagga tattgccacg gaataactag cttactacaa
    11761 accactgtct acaatcaaaa caaattactg atgaaaaaat ccaacaggta attttagcat
    11821 gttctgaacg agatgatcac gatttactga tgtttcaagg agatagtggt aaaacagatt
    11881 tgtttgactt cggaatagga agcagggggt atattggtgt ctattaaata ataaattccc
    11941 attcgatgtg cagacataag gagaaaagta tgaaattatt ttggacaaac aacatatata
    12001 gacagttgct gctaaacagc tgtttttcat cattcggcga cagtattttc tacctcgcca
    12061 ttatcaatta tgtggctcag tacaatttcg ctccgctagc gattttactg atttccattt
    12121 cagagatggt tcccctacta tcgcaactct ttctcgggat tctaggagat tttcaagaaa
    12181 atagagtcaa acacgcactc tggattgcca aaatcaaaat cctgctctac gctattttga
    12241 cagtatttct cgtcttgtcg cccttttcat tagtttcagt cattatgatt gtcatcatca
    12301 acctcatctc tgacaccttg agctacctgt ctgcctacat gatgaacgcc ctctacatca
    12361 gtgtaattaa ggacgacctg catgatgcca tggggttcag gcagtctctg atgagggttg
    12421 tccacattgt cgccaatctg gctggcgcat tccttatcaa tgttatgagt attcaaacta
    12481 tttcccttat caacactctg acttttgtca ttgccttttt gggtctgtat gttattagac
    12541 ataccttgta tgaggttgaa aaaaggattg aaatgtcaca tacagcactg agttttaaga
    12601 aatattttca acatcttaaa cagtcgctgg ctgtgctcct gaggttaaaa gataccgtca
    12661 tactactgtt tctgacgacc agtatgattg ccatcttgga tgtgtcccct cggctgattg
    12721 ccctccgctt catccaacag acactagcac aactgagcat tgggcaactc ctcgccctgc
    12781 tctccatcat catgtcttgt ggagctatcc ttggcaatat gaccagcagt aatctattta
    12841 aaaatatccg tttcacgcac ctcttggttt tctgtgagat ttccctattg actctaataa
    12901 ctagtatcct ttgtcaagcc tatatcgtaa ttttcatgac cagtttcatc agttctacga
    12961 ttatcggcat tctcagccct cgcctacaag cagctgtctt tgcccatatc cccagtgaca
    13021 agatggggac ggtgggctct gctctgagca cagtggacat tctcgccccg tccctgctct
    13081 ccctattagc cctatccata gcatcgggcg tttcggtgca gttagcatcg atatttttgt
    13141 atcttatttt aattgctctt atcttttgtc aatggttagt caagttcaac actcataact
    13201 aacgaaaaag catgtgtaga tttcacatgc ttttaatctc cccaatagtc aggtcaagta
    13261 caacaaagtc acttctttga ttaagcgagt gttctaatat aattataagc gccctgtcat
    13321 taccgaaccc attcgccatt atagttgacg tagtagccat ctacggtcgt attcactgcc
    13381 aaagcacctg agctataagc atagtaccag ttgccattga cctggaacca acctgtcttc
    13441 atatctccat tacttgtatt taggtagtac caagttgaac catcttgata ccagccagtc
    13501 ttcatatcac catttttatt atctaagtaa taccatttgc ctcgtacata tttccaacct
    13561 gttgccatag aaccagagga gccaaaataa taccattttc cgtttacttt ttgccaatct
    13621 gtaagcatct tacctgaagc atctaggtag taccatggag caggtttgct tctatcaatg
    13681 tcaatagtaa catgaaaatc ttgagtccaa cccttagcaa cttcaccaat tggtagtgga
    13741 ttgtaagaat catcgccaaa atttcctagc ttatttaaat aataccaatg accctcttca
    13801 taaatccagc ctgtctttac agcataatta ttatcaaaat aataagttct cttttcagca
    13861 gatagaggat attgttcacc gtatactttt cctgtatttt cagacgtttt tgcctctagt
    13921 acttgtttat ctgtttgttc tagcaaagca ccatcttgtc caaaatagta ccacttctcc
    13981 tgaaggccaa tttcgaagac tggacgatta tcaaataaat catcacgata acctgttcca
    14041 ggaatttcta agtattgcca accgacaacc atctctccaa tatcaccaaa atagtaagtt
    14101 ttaccgtcta ttttatgcca atagattgct ttatgatcat cttttacata atattttcta
    14161 ttatccttat caacaaatcg gccacctgtg gtattcgcaa ataccgtatt tgtagctagc
    14221 aaaccaaaga aaaagactgc tagtagaact tgcatcattt ttttcaaaag tttcatttat
    14281 atatcctcct aaaacgattg tagcaaagac ccgactgcat gtcaatatat aaaaactcct
    14341 caaaaaagca gttacacaac tgcaactgct tttctattct tgcatggtgt aaccaacacc
    14401 acgcacggtt ttaatgtagc ttttttgtcc tttaacatca agcttgctcc gtagatagcg
    14461 gatatagaca tctacgatat ttgtctcggt cgcactttca tacttccaaa cactttccaa
    14521 caattgctca cgagtcaata ctttcttgct tcccataagt gtcgccaaaa ggtcatactc
    14581 acggcgggtc agagcaatca tctcttcacc acgataaacc gtgtgatgtt caacatctat
    14641 cctaagattg cggtaggtcc ttggaacttt catcagactg cagtgttgat caatgaagtc
    14701 ccgacctcgg aagatcgccg aaatacgcgc taccagattt tcgataagga ctggcttata
    14761 gatgtatgaa actgcaaaac gctgaacaac ttccagctct tcttgcaagt cttcccaatg
    14821 atctaaaatc atgatgactg aggcaggttt agttcggctc aatttttctg caaaatcctg
    14881 agccatcata tctcccagat taacgttcaa taaaatcaaa tcatagtctg tctgaagagc
    14941 catggagagg gctttttgcc cctcctctac cagatcaacc cgatactgct ctttctggag
    15001 ttccaaactt aaaaaatgag ctagatttcg ttctttctca agtaataaaa tccgtttccc
    15061 catggctgac ctacttattt ttcgtcatac caagagtagt ggaaggttcc ttctttgtct
    15121 ttacgttggt aagtgtgagc accaaagtag tcacgttgtg cttggatcaa gttagctgga
    15181 aggtcagctg aacggtagct atcaaagtaa gtaatagctg ctgagaaagt tggcactggc
    15241 acaccagctt gaaccgcaag agctacgata tcacgcactg cttgttgata cttagcagta
    15301 acatccaaga agtactcgtc caaaagaagg ttggcaagat ctgcatcgcg gttgtaagca
    15361 tctgtaatct tttgcaaaaa acgagaacgg atgatacagc catcacgcca gatagatgcg
    15421 atatatgcaa atggcaagtt ccagttgttt tctttagagg ctacacgcaa ttgagcaaat
    15481 ccttgtgcgt atgaaatgat ttttgagaag taaagggctt gacggatctt ttcaatcaat
    15541 tcagccttgt ctccttcaaa gttgaaggca gctggttttg gaagcacctt gctagcatat
    15601 acacgttctt ctttgtaagt tgaaatgtag cgtgcaaaca ctgactcagt aatcagtgac
    15661 aatggtacac caaggtcaag agatgattgg ctagtccatt taccagttcc cttgttacct
    15721 gcagcatcaa ggatgtagtc tacgattggt ccatcttggc cttcatcgtc tttacggctc
    15781 aagatatcag ctgtgatttc gatcaagtag ctatccaatt cacccttgtt ccactcagta
    15841 aagatttcag ccatatcctc tgcagaaaga cctagcaagt gttgcatcaa gtcataactt
    15901 tctgcgatca attgcatatc accgtactcg ataccgttgt gaaccatttt cacatagtga
    15961 ccagctccat caggaccgat ataagtcaca catggtttgc catcttctgg tgctttagct
    16021 gagatttctt caagaacatc cgcaaccaat tcgtaggcct ctttttgtcc accaggcatg
    16081 atagaaggac cttcaagagc acctttttca ccaccagaaa ctccagtacc gataaagttg
    16141 atacctgagt ttgccaattc ttcattacga cggatggtat ctttgtagaa agtatttcca
    16201 ccgtcaatca agatatcacc cttgtcaagg tgtggaagaa gggcttggat agtagcatct
    16261 gtaccaggtc cagcttgaac catcagcatg atacgacgag gtttttcgat tgagtttaca
    16321 aaactttcaa cgtcatagct tggtacaaaa ttcttttcag gatggcaagc aatcacatct
    16381 tccgtttttt ctttactacg gttgtagata gcaactgtgt aaccacgtga ttcaatatta
    16441 agggcaaggt tacgacccat tacggccata cctacgacac caaagttagc ttttgtcatt
    16501 tgacactcct cttgtttcat ttgttttatt ttatcatttt tacttttgaa aagaaagaat
    16561 tttgtaacga ctgcttagta gtccaagtca tccgcatgac cagcgccatt tccgacaaag
    16621 tagcctgtct tacagttaag ggtaaagaga taggttccat ctggcttata gaggttgtaa
    16681 taaccattgc cgttaacgat attgacacgt tcaaggatat attggtctcc agtgatatag
    16741 ccacgtgaac gtgaagtcgc tagaatttgt tccaagacac catccgcaaa atcccaggca
    16801 gagttattac tatcatcaat agcagactga ttataggcaa cacgactggc acttctttga
    16861 acagcaaccc ctgcactcga gagacccata ttgacttcac tgcgactact tctagtctca
    16921 tttgaactac ttggttttgg ctcactagtc gtatttgaac ttgcttgact tgaacttgag
    16981 ctgctagttt gacttaaact tgagctagaa gtacttgttt gctggctctt accaagactg
    17041 atagccttat ctagcacttt atcaagctcc gtatttccag ttttaatatc tgtaaattta
    17101 gcatccgatt tggctttggc attggtatcc aacacaccat ccacaatagc tgatttttca
    17161 aattgtgcat tgacatcttg aatagccttg atttgcgttg ctagactatc atatttagat
    17221 ttggcaagcg tatgttcacg actaccttcc agcttatcaa gtaaagtctt gagttgattc
    17281 agtttatcaa actggctatt tttcaaagcc gttttattgc tatctgtgta aaaggcgtca
    17341 taaagtgtat taaaatcatc cacatccgat tgattggctg tagttgattg agaagtttca
    17401 atttccttgg tcgaacgagc cacttgacgg tagacataat aagcactgac acaaataatt
    17461 actgatacaa gcgccaaaac ggtcaaaata aagccttttt tacttttctt ttctgagtcc
    17521 tcttgatcca gacgagaaag gttttgctcc tcttccactt cttcagtcat ttctgttgga
    17581 ttttcatcat ctagcaatag aggatccaag ccttgctcct catcgtccag aggcaagggt
    17641 agtaagatgt cttcagaaga tggaacttcc tccgaagaag cttctgactt ctctacagcc
    17701 tcacgcatct cttgaattaa atcatccaga ctctgagttt caacgaactc ctcttttttg
    17761 tattgacgag tcgcaaactt atccgcctca atttcatctc tgtgttgctt aacatacttg
    17821 tccaaaatgg aatcctcagg caagactcct gcttccactt cttcattttt acgaatagct
    17881 tgaccaactg ttagctcttt tgcttcatca aaatcaaatt gcggttcttg accttctttt
    17941 ttttgacgat ttcgtctttt tttactcatg agtatccttt ctattttacc tcttgccgtt
    18001 tgacacgctg accaaaatat tgatatagat ccactttcaa ggttccgttg tataacttac
    18061 gcttcttatc tgcttggcta ccatacttgc tttcaaaagc ttcatcacta gtcaggataa
    18121 atttgctcca agttttcagc ggtgcaaata cttgccccat ctcagcatag agcttggtca
    18181 cccctgcatc atctgacaaa cgttcaccat aaggcggatt ggaaatgatt actccattga
    18241 ttttatcgga acgtaaatcc tgcacgcgca tctgcttaaa agtaatgtct cctgcaacac
    18301 cagctacctg agcattggcc ttagcaattt ccaccatgcg agcatcaata tcacagccca
    18361 tgatatccag ctcaagctca cggtctactt ttttagccgc ttctgtgcgc acttcttgaa
    18421 tcaagcgatc gctgatccag ttccattcct caaatgcaaa agagcgacga agacctggcg
    18481 ccatctttct agcaatcata actgcctcaa tacagaaagt ccccgaacca caggtcggat
    18541 caatcaaagg cttgtctgga taccagttag aaagttgtaa aatggctgct gccatatttt
    18601 ccttgatagg agcgccacct ttttcggtac gataaccacg tttaaagagg ctagacccgg
    18661 tcgtatcaat catgacagtt gccacatctt tgagaataga gacctcaatc ttaaactctg
    18721 ggccattctc catcagagga accccttctg ggcgagcata gtgtttctgc aatttcttga
    18781 caacagcttt cttagaaata gcctgaacac tgggctcatt gtgaagtttg gacttaacac
    18841 atttagcttt tgaaatcggg aaccgagctc caagtggtaa ataattttcc caatccaaag
    18901 cgaaaactcc ctgaaatagc tcttcaaaag tcttagctgg gaacgttcct acgataattt
    18961 tgatacgatc tgctgcccga agccaaaggt tggtttcgat aatagctctc acgtctcctt
    19021 gaaaacgaac acgtccattt tcaacctgac aatcgtagcc caactctcgc acttcacgac
    19081 caacgacagc ctcaagccct gctgccacag ttgcaattaa attaaattct tttttcatgt
    19141 tacagtcttg caagaccttt ctatatgtcc actttaaaaa atgaggttga gaaaatttct
    19201 cagccccaac ctatatgcaa ttttctataa gccatgtttt gttccagaag tgactaggac
    19261 cacttccttc gataatcatc tgtctaccac taacagctct agctgatagc agtcagaata
    19321 ctacgttcgt ttccgcgtac tccatgcccc gaccaaaatt tgggttgcta gcttgagggg
    19381 tttaccgcgt tccactctct ctgtttccag aaagactccg tcactgtggc actttcaagc
    19441 ctactctggc ctatccaagg acttagccat ttcaactgcc gtaacgattt ctcgtcccta
    19501 ggcttatggt ttcgcctagc acaaacacta caggcatcac agcctgtgct agcatggact
    19561 ttcctcatga gaagcaattc tcctcacgcg attatccaaa aattgcacat ctcaaataac
    19621 tacttaaaaa tctgagttat ctaaaatttg tttaccaaaa acttcttttt ccaatctatt
    19681 caggcgtttc aaaatatcaa aattcgtcat agaacttgta attgccgctt caaggggttc
    19741 tgcttgaact ggtgaaggtt tcggtttacg agttaattct tccttcaaat ccgcaatttc
    19801 ctgacgaagt gacttgacca aggcagcata ggtttcatag tccttgatga catcgtctaa
    19861 aaactcgtca acttctactt tattatagcc acggacttca cgtccaaact cttgttcaaa
    19921 aatatctttc gctgaaaaaa taatacttgc catgtctctc tccattctcg cttgctagta
    19981 ttattatata aaaaaaggca aacaaaaatc aaggtcaaag cttcaatttt cggaaaaatt
    20041 ttcagcaagt tcatttaatt gatcaaatgt taatctcttt ataaaatagt cctcttgatt
    20101 tttcatcttt tggtaaaaat aagctagttt tgtttcattt tcttcatcat aaaaaagata
    20161 ggaactagtc gtgttttcca gcaaaaactg ctggtaatct cttaactgcc ccttgtgttc
    20221 atagcgagga taggcatatt tgacaaagtc tacctgctta aagcgactca gtttcatctg
    20281 attgccttca ttccaatttt ccccatgggt ttcaaaagca aaaatggtgg ccaactggaa
    20341 accgtattcg gttttcatct cctgagcaac ctctaaaacc caatattcaa aacccaaact
    20401 ccctgtaaac acaagccaag acaccccatc tgctgccata gcctctaaat ctttacgtat
    20461 cgctttttta atcaatttaa gacgaggatc cttatcagaa aataaaccca aatcaaaagc
    20521 agaatagcct aaaaccaaag ctgtagccat ttttaaccct ttctgtgcaa attatggtat
    20581 aataaagtga tgttattgta ccaataagga gaattatggt caactatcca cataaagttt
    20641 catcacaaaa aagacaaaca tctctttctc aacccaaaaa tttcgcaaat cgaggaatgt
    20701 cttttgaaaa gatgatcaat gctaccaacg actactattt gtctcagggc ttggctgtta
    20761 tacataagaa accaactcct attcaaatcg tacaagtgga ctatccacaa cgaagtcgtg
    20821 ccaagattgt tgaagcctat tttcgacaag cttcaacgac ggactattct ggcgtttata
    20881 atggatatta catcgacttt gaagtcaagg aaacaaaaca aaaacgtgcg attccgatga
    20941 aaaattttca tccacatcag attcagcata tggaacaagt ccttgcccaa caaggaatct
    21001 gctttgtcct tcttcacttt tcttctcagc aagaaaccta cttattgccg gcattcgatt
    21061 tgattcgctt ctatcatcaa gataagggac aaaaatcaat gccacttgaa tatattcgag
    21121 aatatggata tgaaatcaag gctggtgcct tccctcaaat tccttatctc aatgttatca
    21181 aagaacattt attaggtggt aaaacaagat gaacaaacca acgattctgc gcctaatcaa
    21241 gtatctgagc attagcttct taagcttggt tatcgcagcc attgtcttag gcggaggagt
    21301 ttttttctac tacgttagca aggctcctag cctatccgag agtaaactag ttgcaacaac
    21361 ttctagtaaa atctacgaca ataaaaatca actcattgct gacttgggtt ctgaacgccg
    21421 cgtcaatgcc caagctaatg atattcccac agatttggtt aaagcaatcg tttctatcga
    21481 agaccatcgc ttcttcgacc acagggggat tgataccatc cgtatcctgg gagctttctt
    21541 gcgcaatctg caaagcaatt ccctccaagg tggatcaact ctcactcaac agttgattaa
    21601 gttgacttac ttttcaactt cgacttccga ccagactatt tctcgtaagg ctcaggaagc
    21661 ttggttagcg attcagttag aacaaaaagc aaccaagcaa gaaatcttga cctactatat
    21721 aaataaggtc tacatgtcta atgggaacta tggaatgcag acagcagctc aaaactacta
    21781 tggtaaagac ctcaataatt taagtttacc tcagttagcc ttgctggctg gaatgcctca
    21841 ggcaccaaac caatatgacc cctattcaca tccagaagca gcccaagacc gccgaaactt
    21901 ggtcttatct gaaatgaaaa atcaaggcta catctctgct gaacagtatg agaaagcagt
    21961 caatacacca attactgatg gactacaaag tctcaaatca gcaagtaatt accctgctta
    22021 catggataat tacctcaagg aagtcatcaa tcaagttgaa gaagaaacag gctataacct
    22081 gctcacaact gggatggatg tctacacaaa tgtagaccaa gaagctcaaa aacatctgtg
    22141 ggatatttac aatacagacg aatacgttgc ctatccagac gatgaattgc aagtcgcttc
    22201 taccatcgtt gatgtttcta acggtaaagt cattgcccag ctaggagcac gccatcagtc
    22261 aagtaatgtt tccttcggaa ttaaccaagc agtagaaaca aaccgcgact ggggatcaac
    22321 tatgaaaccg atcacagact atgctcctgc cttggagtac ggtatctacg attcaactgc
    22381 tactatcgtt cacgatgagc cctataacta ccctgggaca aatacccctg tttataactg
    22441 ggataggggc tactttggca acatcacctt gcaatacgcc ctgcaacaat cgcgaaacgt
    22501 cccagccgtg gaaactctaa acaaggtcgg actcaaccgc gccaagactt tcctaaatgg
    22561 tctcggaatc gactacccaa gtattcacta ctcaaatgcc atttcaagta acacaaccga
    22621 atcagacaaa aaatatggag caagtagtga aaagatggct gctgcttacg ctgcctttgc
    22681 aaatggtgga acttactata aaccaatgta tatccataaa gtcgtcttta gtgatgggag
    22741 tgaaaaagag ttctctaatg tcggaactcg tgccatgaag gaaacgacag cctatatgat
    22801 gaccgacatg atgaaaacag tcttgactta tggaactgga cgaaatgcct atcttgcttg
    22861 gctccctcag gctggtaaaa caggaacctc taactataca gacgaggaaa ttgaaaacca
    22921 catcaagacc tctcaatttg tagcacctga tgaactattt gctggctata cgcgtaaata
    22981 ttcaatggct gtatggacag gctattctaa ccgtctgaca ccacttgtag gcaatggcct
    23041 tacggtcgct gccaaagttt accgctctat gatgacctat ctgtctgaag gaagcaatcc
    23101 agaggattgg aatataccag aggggctcta cagaaatgga gaattcgtat ttaaaaatgg
    23161 tgctcgttct acgtggaact cacctgctcc acaacaaccc ccatcaactg aaagttcaag
    23221 ctcatcatca gatagttcaa cttcacagtc tagctcaacc actccaagca caaataatag
    23281 tacgactacc aatcctaaca ataatacgca acaatcaaat acaacccctg atcaacaaaa
    23341 tcagaatcct caaccagcac aaccataaca tttatcaccc agatttttct gggtgatttt
    23401 gtcatagcac tattgtattt atgtgcttaa caaaagcctg agaagacatc ttctcaggct
    23461 ttttctgtac tataaacctc attggaaaag atagagactg cttccgtaat cttgttaaga
    23521 ggttttacta aatactagtc tttcttcgtt tttactacaa agagagcaga tagggctagg
    23581 ctaacacctg ctaggaagag ggctgtgtca gattgactct cacctgttgc tggcaagatt
    23641 tgttcaggtg tttctggtct agctatttct tgcttataat ctggcgtctt accttgctcg
    23701 gaagctaaag agctaagttt aaactcaggt ttctctacag ttggagcatc tggtttcgta
    23761 gcagaatctt ttaattggtt gagataatct gcaaagtatt ccaccattct ttccgtcaag
    23821 agatggttat ccgtcgcata tttcatgctt gcctgaacgc tagctacttc ctcttgattg
    23881 tctttgtctg ttaatttctg aaccttagcc aaagctgctt catagcctga caagtcaaga
    23941 ggtgtttctg ctacctgtgg acgagtaaag ataagttccg ctgcagattg gtatttatcg
    24001 ccaccatctc cgtaagtctt agtacctgta aggacaattt tcttagcctt aattgtctta
    24061 ccaaaatcaa tgtcttttgg cttattgtta tctggccaat cagttgcagt aaaggtatgc
    24121 tccttgccag actcatctgt cacaacaagt ttcacatcac gcaagttacc atttgaaccc
    24181 gatccacgtg gaacgtaacg aagtccagtg atttcagttg gttctttcaa gaccatggtt
    24241 gcaggcttgc ctacatctcc accattccaa gatgtatgcc atagactaga cacattgcca
    24301 tcaaaagcat ttgcaagacc ttcttgagcc tgagcaggag ctgtaagact tgcaaaatca
    24361 tctgctacca aagccgtttt cttctgaacc aaagcattct tcaaggcttc aatcttggca
    24421 atctctgcac gcgcttcttc cacactgata tcatcatcgg cctgactgag gttaaagacc
    24481 gcctctttca aagcatccat agactctttg gtgtagttag tcatggcaac cgttggcaag
    24541 tagttcttca gagcattttc tgtcaacatc ttacctgtta gggtaatttc ttcgatttga
    24601 agattatcca tcatgaagtc gttataacca cggaagttgg catttccacc agaatcacca
    24661 cgagtattac ttgcattgcc agttgagtag atacctaccc aagtatcccc tgtttctgca
    24721 cctgtcacaa ggaaggttgc cttcttggct ttcttagaat ctgtccaagt atttggcaat
    24781 tcatgcattt ccaagttgct tgcttgagtg ccacgacgac ctgactggaa ttctccctta
    24841 ccgactacaa aagcataggt attgtctgaa cctgcttcgt attcaaaggt tacacggtag
    24901 gtcttacctg cttcaaaacg gaagttttgc ggaatagttt ggtaaaccaa gttacgacgg
    24961 ctcactagtc catttgtctt gagtgaccaa tttccttcga taacatcatc gactttctta
    25021 ccattccaac cacgttgtgt atatggatcg tgtttttcag acaagtgagt gcggttatct
    25081 tcaacacctt caacaccacc cactacaaat gggaagatac cctgagcaac attttcaaag
    25141 tcttgcttga aggtgccttt acctgtatca tgcttgtctc cgtacatgct tgaattgttt
    25201 tcaaaggtac gaatttcatc aaagtaagtt gcttgatcac cagcttcacg actcaatgtc
    25261 agagtaacat ttgagacgtc cgatccagtt gtaaagaagg cgtacatgtt ttggaagtaa
    25321 cttgtatcgt caactgtagc attgtcacga cgtgtattgt gggcgtaggc ttttacatag
    25381 ttgagggcga gagacttatt ggtataagta gtcacttctt tttcaccagt attcacagtg
    25441 atacttgcct tggcattact acggttatcg acaccgacat aaacggcata cttggtattt
    25501 ggtttcaagc cagttaattt ctgagtgaga ctaacttttt ctttgtttcc ttgaatacga
    25561 agcatatcgt ttgccccttg agacttgaca atttctgcct tagaagcatc gcctgaaatg
    25621 gtccaatgtt tcaaggtacc gctattaaat ccttggtcat agatgtgcat gccttcactc
    25681 catgacattt caggattggt ttgtttcgaa cgatagagaa cgtatggttg atttgctaga
    25741 agatctaggg taattttacc atcttttaca gttagttcct gctcttctgt cttaccttgg
    25801 tcagttagct tgtaaaggta aaccttgctc tttgcccaat cgcttggaag ggtccaagtt
    25861 gttgcaccag tctgcgtatt gaagtagtac atcttttcct tatcagtagg aagtttctta
    25921 ccattcgcat cccagttcca aggagtcaag taagctgaac catcttggat gacacgtccg
    25981 ttgagagtta ctgtacgttc gcgatattgt gggctattga catcatttga cttacgagtt
    26041 acaactactt tattattgtc agcatctacc aattccactc gcatttctgg agtccattta
    26101 taggtgctac cgttatcggt catagtcacc ggtgtaccat tttcccattt acttacagtg
    26161 aagtgttgga agtacttagt catgacgtca tgggcaaata agttggttac atagccattg
    26221 tagtcacttc ttccttgcca gccttcaaag tctttcatgc tgtagccacc tagcagtgga
    26281 tagttggctg caccaccata acttctgtag tcccctaccc aagcatcttt ttggtggtta
    26341 cggataaagc gggtgatggc actgttgata cctttattgg tgtagccacc gtaggtcaag
    26401 tcagctgccc agtgatggaa ggtagagtcg tactcaccac catggcccca ctcgatcgca
    26461 aagcgccagc cttgtttgtt aatttcttta gcaagaacgt gggtagccca ggcaccgtta
    26521 tcacctgatt gaccattacc ccaaacgtcc acatagataa agtcgagacc gtcaccaagt
    26581 tttttcttca aatcttccca acgtgccaaa cgaccatgag ctaggtcata ggcagcatca
    26641 atgttgatac cttgatctag ccagttccaa ccatagctat aacttccatc tggattctta
    26701 cggagaattt tttcattgaa gtatttagac tcaggataag tttctgaagc gttaacgtgg
    26761 atacctagat gagctccata tttcttagcc ttctcaatta gggtcttgaa gtcttcgaca
    26821 ccaccgatac gcttaccaat atcagcatag ttcaagtgac cagagtcgtg accttcacta
    26881 ccatatcctt taaggagaac accttgccca agaccatctg tgtggagatt gattttcttg
    26941 ataccatcca aggtcataag gaatgggttt tgtgcttgag aaccaaagtt catcgcgata
    27001 cggtaagctg tgatatcctt aactttttcc caaccttgag ggttgttcat aatgctacga
    27061 taagcaatgg caccatcttg ccaatcgact ttcttgtctg cattggcatc ttcagtgata
    27121 acaaccttag cacttggaag ttccttcgtg tattctggga aaacaatgcc cttataagct
    27181 ttttcccatt gccattcaga gctgtggatt cctacatagt tggcatttcc gactgtttct
    27241 ttataagctg tcaaacgagt ccagtcattc gaaccaccac catagctatt ttgagagtta
    27301 ctccaaacac cagcagcaag cttatctgta gaaacaaatc catacatgta acccttagcc
    27361 aaatccttca ttggattggt tacatcgata tgatcatctc cgctgacatg cgtattgttt
    27421 gacatggttg ccccatcaaa cttagcacca gtttgatcac tagaaacaga gactaaagca
    27481 ttgccgagga aactaataga agaaagtagt tttctttcgt catcaatctt ttgacctgga
    27541 gtgacttgat tgtggttgac aatcttggtc acatcaaagt gcaattgatt gtccacaact
    27601 tgcaagcgta ctgtcatttc cgcattgatt aagtgagcat catcgcgaat cttcatcaag
    27661 tactctgctg ttgtctcatt gattttctta taagtgactt caggggtgat tcggtggtta
    27721 ttgataaaga cttggttgaa ctgttgcacc tgtcctggca aagtatgtcc attcaaggtg
    27781 tattccttga cacgagggaa ggcttggtca attactgcct taagtacctt agactggatc
    27841 gtatcataag tcaccttgct atcgtcaaca accggacctg tttctttctg ggcaggagta
    27901 tcatccgctt ttacgccttc ttgattgtct gttttaacgc tgacaaccgt acggtcattg
    27961 ccataagagc ccgccttgag aagaatcttc ttctcatttt taagatggtc attgaccgca
    28021 gctggtagag tcactgtgtc aaagagattg acatcgttat tgctggcatt tagctgaccg
    28081 tctgacttga gagtgataga gagacggttt gttgatcctg tttcaggagc aacaacacga
    28141 ctacctctat accaagtgct agttgttgga gatttatact cccagaacca gccatccttg
    28201 tcataaccga caaaaacatt attattggta tctttaaatt tcaggaagac accaaagcgt
    28261 gatttgccct tttcagaatc atctttgaag gttaaatcaa cagttgcatt tccattggca
    28321 tcaacggtca agcccttctt ttcaaacagg gctggtttac ctgcgttatc attttgagca
    28381 gttgaggata gttggttgta gcggacacct ttttcttctc ggatagtgac tgttcccttt
    28441 tgttcttttt tctctaccgt ttgccattca ggggttaccg tcttaggtgt ttcaggttta
    28501 gcagctgcag gtttatcctc ttttggtttt tcttcagccg gtttttcttt ttcaagtgct
    28561 aatagttctt cttctgtctt aggtccatct gtaacttctg gagaaccttg gtcttcttcc
    28621 accttaggcg cttcaaaatc acgcccatca ttctcttttg ctgttgcaag agcagtagct
    28681 aaatcagctg gtaagttcgc cgtggaacca gactgcacgc tatctgcaag aaccggactt
    28741 gtcccaaaga atgcagctcc aatcataaca gaagcaacac ctaatgaaaa tttccgaata
    28801 ctatatttac aacgtttttc aaataatcct ttattcataa acttctaaat cctttcattt
    28861 ttgggcaaac gtttacattt cctttttaaa aaatactcct tcctctgaaa gtgcaatgct
    28921 taaccctgat aaataaaaaa taattatact tttaatataa caaataataa ctgataaagc
    28981 aataggaaac aagtaaaatt aacaaaaatt ttctctattc tgacaaaaag aggctccaac
    29041 ttttgggggt cagt
//
LOCUS       DAVHSI010000025        28100 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.025, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000025 DAVHSI010000000
VERSION     DAVHSI010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28100
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.025"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..377
                     /locus_tag="VVR21_001296"
     CDS             <1..377
                     /locus_tag="VVR21_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU6055176.1"
                     /translation="FEPHTYGIFERISNGLKVNLNNFRTNKDSLWSNAQDANQAKKLP
                     QLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTNNSYDQPSLNFD
                     QKNHMVTITINSNGNLEFELHF"
     gene            392..1120
                     /locus_tag="VVR21_001297"
     CDS             392..1120
                     /locus_tag="VVR21_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEU6055177.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            1133..2899
                     /locus_tag="VVR21_001298"
     CDS             1133..2899
                     /locus_tag="VVR21_001298"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU6055178.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            3045..4196
                     /locus_tag="VVR21_001299"
     CDS             3045..4196
                     /locus_tag="VVR21_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU6055179.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            4341..5225
                     /locus_tag="VVR21_001300"
     CDS             4341..5225
                     /locus_tag="VVR21_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU6055180.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(5433..5510)
                     /locus_tag="VVR21_001301"
                     /pseudo
     CDS             complement(5433..5510)
                     /locus_tag="VVR21_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5714..5965
                     /locus_tag="VVR21_001302"
     CDS             5714..5965
                     /locus_tag="VVR21_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU6055181.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            5953..6243
                     /locus_tag="VVR21_001303"
     CDS             5953..6243
                     /locus_tag="VVR21_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055182.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(6426..6553)
                     /locus_tag="VVR21_001304"
                     /pseudo
     CDS             complement(6426..6553)
                     /locus_tag="VVR21_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(6647..7978)
                     /locus_tag="VVR21_001305"
     CDS             complement(6647..7978)
                     /locus_tag="VVR21_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU6055183.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLYGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(8000..9511)
                     /locus_tag="VVR21_001306"
     CDS             complement(8000..9511)
                     /locus_tag="VVR21_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU6055184.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(9722..10669)
                     /gene="arcC"
                     /locus_tag="VVR21_001307"
     CDS             complement(9722..10669)
                     /gene="arcC"
                     /locus_tag="VVR21_001307"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU6055185.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVIKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(10834..11850)
                     /gene="argF"
                     /locus_tag="VVR21_001308"
     CDS             complement(10834..11850)
                     /gene="argF"
                     /locus_tag="VVR21_001308"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU6055186.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(11908..13137)
                     /gene="arcA"
                     /locus_tag="VVR21_001309"
     CDS             complement(11908..13137)
                     /gene="arcA"
                     /locus_tag="VVR21_001309"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU6055187.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13893..15572
                     /locus_tag="VVR21_001310"
     CDS             13893..15572
                     /locus_tag="VVR21_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU6055188.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSLLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFVTYRNELYKEDLALGAEVS
                     GPTLSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(15612..17696)
                     /locus_tag="VVR21_001311"
     CDS             complement(15612..17696)
                     /locus_tag="VVR21_001311"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU6055189.1"
                     /translation="MKPLLETIDTRLGTTNRHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSTCKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKTCQDAPLFEITGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            17867..19147
                     /locus_tag="VVR21_001312"
     CDS             17867..19147
                     /locus_tag="VVR21_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU6055190.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            19238..21883
                     /locus_tag="VVR21_001313"
     CDS             19238..21883
                     /locus_tag="VVR21_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU6055191.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            21967..22836
                     /locus_tag="VVR21_001314"
     CDS             21967..22836
                     /locus_tag="VVR21_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU6055192.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            22830..24710
                     /locus_tag="VVR21_001315"
     CDS             22830..24710
                     /locus_tag="VVR21_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU6055193.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGSETAQFSILSSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTVNQWHTIATASTIY
                     TT"
     gene            complement(25347..26152)
                     /locus_tag="VVR21_001316"
                     /pseudo
     CDS             complement(25347..26152)
                     /locus_tag="VVR21_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(26097..26279)
                     /locus_tag="VVR21_001317"
     CDS             complement(26097..26279)
                     /locus_tag="VVR21_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6055194.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            26614..>28100
                     /gene="pcpA"
                     /locus_tag="VVR21_001318"
     CDS             26614..>28100
                     /gene="pcpA"
                     /locus_tag="VVR21_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU6055195.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYL"
BASE COUNT         8395 a         5441 c         6139 g         8125 t
ORIGIN      
        1 aatttgaacc tcatacctat ggtatttttg agagaataag taatggattg aaagtgaatt
       61 taaataattt tagaacaaat aaagattcac tatggtctaa tgctcaagat gcaaatcagg
      121 caaagaaact accacaattg accaagaaag gtgcgattaa gtggattgaa gaacattata
      181 tcaaagatac tcagtttgga gagaaaaggg ttacaaagat agtattaaga ggtatagata
      241 aacttcctac tattcattca ttatcaggaa caaataattc ctatgatcag ccatctctca
      301 attttgatca gaaaaatcat atggttacta ttaccattaa cagtaacgga aatcttgaat
      361 tcgaacttca tttttagaaa ggagtgagtt tatgtctcaa gatgaaaaat taattcgtga
      421 acagatttgt gatgtttgtc ataagatgtg gcaacttggt tgggttgctg ctaacgatgg
      481 gaatgtatct gttcgattag atgaggatac cattcttgca acacctactg gtatcagcaa
      541 aagttttatt acaccagaaa agctggtgaa gttaaatctt aaaggagaga ttttagaagc
      601 agaaggtgat tactgtcctt ctagtgaaat taaaatgcac attcggtgct acgaagaacg
      661 tgaggatgtc cgttcagttg ttcacgcgca tccaccgatt gcaacaggat ttgctcttgc
      721 acacattcct ttagatactt attcactaat tgagagcgcg attgtggtag gggcaattcc
      781 tataacgcca tttggagttc cgtctacaat ggaagtgcca gaagcaatta caccttatct
      841 gcccgatcat gatgtcatgc tattagaaaa tcatggagct ctgactgtcg gaagcgatgt
      901 cattacagca tactaccgta tggaaacttt agaattagtc gcaaagacaa ccttccacgg
      961 aagaatgtta ctttctacaa agggcattga ggagcaagaa attgctcgtc cgactttaga
     1021 acgtctattc tcaatgcgag aaaattataa ggttacaggt cgtcacccag gctaccgtaa
     1081 atataatgga gatggtagta tgaaagaaac agaaaaataa gaggaaaata gtatgattca
     1141 acatccacgt attgggattc gtccgactat tgatggtcgt cgtcaaggtg tacgcgaatc
     1201 acttgaagta caaacaatga acatggctaa aagtgtggca gatttgattt caagcacatt
     1261 gaaatatcca gatggggaac ctgtggaatg tgtgatttct ccatctacca ttggtcgtgt
     1321 tccagaggct gcagcttccc atgagttgtt taaaaaatca aatgtttgcg caacaattac
     1381 agttacacca tgctggtgtt atggtagtga aactatggat atgtctccag atattcctca
     1441 tgctatttgg ggatttaatg ggacagaacg cccaggagct gtctatcttg cagctgtact
     1501 agcttcacat gctcaaaaag ggattccagc ctttgggatt tatggtagag atgttcagga
     1561 agctaatgat acagatattc cagaagatgt caaagaaaaa cttttacgtt atgcgcgtgc
     1621 agctcttgca actggcttga tgagagacac tgcttaccta tcaatgggta gtgtttcgat
     1681 ggggattggc ggttctattg taaatccaga tttcttccaa gaatacttag gaatgcgaaa
     1741 tgaatcggta gatatgacgg agttcacgcg ccgtatggac cgtggtattt atgacccaga
     1801 agagttcgaa cgtgctatgg tttgggtaaa agaacatatc aaagaagggg ttgaccgaaa
     1861 tcgtgaggat ttgattcttt ctaaagaaga gaaagaaaaa caatgggaat ttgttattaa
     1921 gatgttcatg attggacgtg acttaatggt tggtaaccca agacttgctg aacttggttt
     1981 tgaggaagaa gcggttggtc accatgcttt agtagctggt ttccaaggtc aacgtcagtg
     2041 gacagaccat tttccaaatg gagattttat ggaaactttc ctcaatactc agtttgactg
     2101 gaatggtatt cgaaaaccat ttgtatttgc gacagagaat gattcactaa atggtgtgtc
     2161 tatgctcttt aattatctat taacaaatac tccacaaatc tttgctgatg tgcgtactta
     2221 ttggagccca gaggctgtta aacgtgtaac gggacatact ttagagggtc gtgctgcagc
     2281 tggcttctta catctaatca actctggttc ttgtacattg gatggtacag gtcaagctac
     2341 tcgagatggc aaacctgtta tgaaaccatt ctgggagttg gaagaaagtg aagtgcaggc
     2401 tatgcttgaa aatacagact tcccaccagc aaaccgcgaa tacttccgtg gaggaggatt
     2461 ctcaactcgt ttcttgacga agggggatat gccagtaaca atggtacgtc tcaatcttct
     2521 aaaaggggtt ggtccagtgc tacaaattgc agaaggttat acacttgaac ttcctgaaga
     2581 tgttcaccat actttagata atcgtacaga tccaggatgg ccaactactt ggtttgctcc
     2641 acgtttgaca ggaaaaggtg ctttcaagtc tgtctatgac gtcatgaata attggggagc
     2701 taatcacgga gccataacat atggacacat tggagcagac ttgattacct tggcttctat
     2761 gttgagaatt cctgtcaata tgcataatgt acctgaggaa gatatcttta gacctaaaaa
     2821 ttggtcctta tttggaacag aagatctaga atcagcagac tatcgtgcat gtcagttgtt
     2881 gggaccacta cataaataaa acttgtttat ataggaggtg aacttacgtc cctcctatcc
     2941 ttttaaaaag atttgttaaa caattcacaa ataattgaaa acgaatacaa aaagtaatat
     3001 aatgatgtta aatagatagc gcaaaggcgc aggaggaaaa ttatatggct acattttatg
     3061 ttccggcagt caaccttatt ggtaaaggtg ttgtaaatga agtgggtcct tatatcaagg
     3121 aacttggcta taaaaaggca cttttggtga cagataagta catcgaaggc agtgacattt
     3181 tacctaaggt tttaaaacca ctggatacag aaggaatcga atatgtcatc tttagcgatg
     3241 tagagccaaa ccctacttgt aagaatgtca cagatggggt agctgctttg caagaacatg
     3301 gatgtgattt tatcatcagt cttggtgggg gttctccaca ggatgcagct agttgtattt
     3361 ctatcatggc tacaaatggt ggaagaccac aggattatga agggcttcat aagtctgcta
     3421 aaaaaggctt gccagttgtg gctatcaata caacggcagg aacttctgca gaaatcacta
     3481 ttaactatgt gattactgat gaagaacgca aggttaagat ggtaatggtt gacaagaata
     3541 gccttgctct tatctctgtc aatgacccgg aactcatgct ttccaaacct caagccttga
     3601 ctgctgctac tggtatggat gctctgactc acgctgttga agctttggta acacctggtg
     3661 cttatgatgt aaccaagaaa ctgtctattg gtgctattga gcttatcaag gaatatcttc
     3721 ctcgtgctgt agaaaatgga catgatattg aagcgcgtga aggtatggtc aatgccatct
     3781 tccttggtgg tatgagcttt aataatgctg gtcttggtta tgttcactca atggctcacc
     3841 aactcggtgc agtatataat ttgccacatg gtgtttgctg tgccatgttg ctaccagtta
     3901 tagagcgtga aaatgctaaa cgtgtaccag aagctttccg caatgttgcc aaagccttgg
     3961 gacttcatgt agaaggtaaa tcagatcaag aatgtgccga ttatgcgatt gctgagattg
     4021 agaagctttc tgagacagta ggtattccta agaaattgac tgaacttggt attgaagaaa
     4081 aagatttcga ctttgaatac ctttctaaga atgccttgat tgatgcctgc gcaccaggaa
     4141 atccatttat gccaacctta gaagaaacga ttgcctttta taaagagtta ttttagcaag
     4201 agattagacg acaataggac aattcacctc taattattga catttcagga aaaatcgcag
     4261 taaaaacggc acagccttct ttaaatgtgc tataatacta gaaaaatact tgtggaggtt
     4321 ccattatggc aatatttttc atgatttttc tgattgtttg tgtgctccta ttggtgatag
     4381 tcacactgag tacagtttat gtggttcgtc agcagtcggt ggcgattatt gaacgctttg
     4441 ggaaatacca aaaggttgct aatagcggta ttcatattcg cttgcctttt gggattgact
     4501 cgattgcagc acggattcag ttgcgcttgt tgcaaagtga tattgtggtt gagactaaga
     4561 ccaaggacaa tgtgttcgtt atgatgaatg tagcgactca gtaccgtgtc aacgagcaga
     4621 gcgtgacaga tgcctactat aaactcatac gtccagaatc tcagattaaa tcttatatcg
     4681 aagatgctct tcgctcttct gttccaaaat taaccttgga tgaattgttt gagaaaaaag
     4741 atgagattgc ccttgaggtt caacaccaag tagcagaaga aatgaccact tacggctaca
     4801 ttatcgtgaa aaccttgatt accaaggtcg aaccggatgc agaagttaag caatccatga
     4861 atgaaatcaa tgcggcgcaa cgtaagcggg tcgcagcaca agaattggcg gaagctgaca
     4921 agattaaaat tgtcactgca gctgaagcag aagcagaaaa agaccgcctt catggtgtgg
     4981 ggattgccca acaacgtaag gcgattgtgg atggattggc agagtctatc accgaactca
     5041 aggaagccaa tgttggcatg acagaagaac aaatcatgtc tatcctcttg accaaccagt
     5101 atttggatac cttgaatacc tttgcctcta aaggaaatca aactatcttt ttaccaaata
     5161 ctccaaatgg tgtggatgat atccgaacac aaatcttgtc agcccttcgc gctgagaaga
     5221 aataatagac taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttgccgta
     5281 tagatgttac tgactttgtc agttctatct gcaacctcaa aacagtgttt tgagctgact
     5341 tcgtcagttc tatctgcaac ctcaaaacag tgttttgagc tgacttcgtc agttctatct
     5401 gcaacctcaa aacagtgttt tgagctgact tcgtcagtct tatctactac ctcaaaacgg
     5461 tgttttgagc aacctgtggc tagtttccta gtttgctctt tgattttcat tgagtacaaa
     5521 gagcttggca acaggctctt tttgtattgc gtttattaag aaaaacaaaa aacatcgata
     5581 tacatttaac taaaaattat tgtatgttat ctcccttaat taggaatgat aagggaataa
     5641 ctagaaagat ttgtgaatac aaactatttc tgatatacaa aatatacagt aataatgaat
     5701 gatgggagat gggatgaaag aatttcaatt tgagagaaag cagcgttttt ctttgaggaa
     5761 atatgcaata ggagcttgtt cggtcttgct aggaacgagt ttattttttg ctggtatggg
     5821 tgatcagcct gtacaggata cagaaacgag ttcagcacta atttcaagtc attatttgga
     5881 tgagcaggat ttatctgaaa agctgaaatc tgagttgcaa tggtttgaat tagaaaacaa
     5941 gcttttgaac ttatgggagc attaggttac tatgaaggat ttgttcctta tgtttcaaat
     6001 caatacaaaa accaagctga agaagaaggc aaaccgctat ctgataaata tattttcgaa
     6061 aaaatcttag gaaaaacata tgcagccttt aaaaaagatc aaattaatga gcgtgtcgag
     6121 aaattaggta agttaaaacc tattacaata aattacaacg gaaaatcaga agtaattgat
     6181 agtaaagaaa aattacaaga gcttatgaat aaagccgtta aagacgaagt ggctcaaata
     6241 tagtaaaatg aaataagaat aggacaaatc gttcaggaca gtcaaatcga tttctaaaaa
     6301 tgttttagaa gtagaggtgt actattctag tttcaatata ctataaaatc aggcaatacc
     6361 acggctaaaa agtttgagtt tatcgaaaca ccagtgcaaa aactgaaaaa atcgatttat
     6421 aaagctcatc tcaaagattc agatgacttt agaccagaaa catccacata aatctttttg
     6481 aaagctgttt gaagctttgt ccttgctttc ttagttcata gatctgaact ttatcttcat
     6541 aactcaattt cataataaaa caccccaaaa gttagattta ttctgtctaa cttttggggt
     6601 gcagttcatt aatcggtcga tttttttggt agaaacagtt gcctgattaa gttgcaagtc
     6661 gatagacggc ttcggcataa atatccatag cacggtacaa atcttctaga acggcacatt
     6721 catttgcctg atgttctgtc tgcttcgctc ctgggaataa ggcgccgaag gctacacaat
     6781 ttggcatggt gcgagcaaaa gtggcaccac cggatgaaat agcaggactg ttatcgccag
     6841 tcttttcttg gtagatttgc atcagtgtgc taacgagttt actgtctttt gcgacgtata
     6901 gaggcgctag atagtcaaac tcttcgtagc ggagttggta gttttgtgca catcttgtaa
     6961 gcaactctac tagttcttcc ttgtcagcta agacaggagt ccgaatgtca atacggattt
     7021 cagaacgttc atgattgatc atgagacctg cgacattaaa ggataggtga ccagaaggtt
     7081 catctgctat atcaccaaag atttgtcttc ctgtgccgtc ttgacctgct tgtgttgcaa
     7141 gaaaactgag agcagggtgt tcttggagag gagcaagaat ggtagctagt cggatgacag
     7201 cattgatacc ttgactagca tccttagcat gctttggcac tccgagaacc gttacggttt
     7261 gttcagtggt ttggtaatca taaccagctt ctttgagacc gttacaaacc tgttcataga
     7321 ggggaccttg gtagttggcc ttgtctggta caacgttaaa ggcgcctcct acttcaagct
     7381 ctagttgatc cgatccaggg ccataaagtt tgacctgtag aagccctttt tcagcatagg
     7441 tcagaggaaa agatgagtca ggtgcaaagc ccatgctggc ctgttcttcg atggtattgt
     7501 agcgtgccat gcagcgccag agggtttcct catcggtacc aaagataaag cgtacgcgct
     7561 ttttgaactg aataccttgg tccagcaagc tttttactgc atagagagct gcgagcgaag
     7621 ggcctttatc atcttggaca ccacgtccga atacccagcc gtctttgata gttgcttcaa
     7681 atggcggtgt ctgccaatct gcttcatcac ctgatggaac aacatccaaa tgacagagaa
     7741 tggccagaag ctctgctccc tgaccgattt ctgcatatcc gtaataacct ttagggtcaa
     7801 gataggtagt gaaacctatg tctcgacaaa tctctaaagt tttttctagg acatcttgga
     7861 ttgcttgtcc aaaaggtgtt ccattttctc cttcattgag tactgaagga taggaaatca
     7921 aggtttttaa tgatataaga aattcatctt taacttgatt tgttatatct attttcatgg
     7981 aatcacctca ctcactattt tataggaatg gaaggaaggt tccaaggaga agaagggcga
     8041 tggtcactac aataatagcg actacgagtt tgcccatgaa tttccaccaa gtaccaatgt
     8101 tgatacgtcc aagtgcaaga gctcccatca caataccaga tgttggtgca atcaagttca
     8161 agacacctga agcagattgg taagcagtga taatcaagct aggacggaca tttacaaatt
     8221 ctccaagtgg agccatgata cccatagttg cgctggcaag accagatgaa gatgggatca
     8281 agaatgacat aggtagatag aagatataag ttacaacgat aaagacttgt gaagatagac
     8341 cgctcaagcc ttctttaccc cagttgagga ttgtatcggt aatcataccg tcgttcatga
     8401 taacttgaat accacgagca atcgctacga tcaaggcaac actgagcaag tcagcagcac
     8461 cattcatgaa ggaagagata atcttatctt ctttaagacc ataaataaca ccaatcagga
     8521 tacccataaa ggcaaagagc attgcgcctt ctgggaagta ccaagtacct agtgcagaag
     8581 tagatgaacc gacaatatta ccaataactg gaagaccagt caaccaagca ttaaagtcat
     8641 caaaaatggt aacgccaagg tctgtccatg gaatgaagct caataccatc aagatgaatg
     8701 tcaacacaaa taagaagaga actgattttt gtttgctgct aagtgtagat tctacagatg
     8761 aagattcttc tacgttaaag tgtttcaaat cttctttgcg agtactataa accagtgact
     8821 tagtcggatc tttttgaatc ttatccgcat aacggtaaac aaaccaagta ctaagagcag
     8881 tcaaggtaac ccagaagatc agacgaagta cgataccgtc ccctgtacca actcccgcag
     8941 tcgctgaagc aatacctgtc gcaaatggat tcagagtaga tgccaaacag ccgatttgag
     9001 aaccgagcaa aataattgca acaccagtca ggctatcaaa accaacggcc atcataactg
     9061 gcacaaggag tggatagaag gccattgttt cttcacccat accataagtt gtaccaccga
     9121 gggcaaacaa aggcattagt accaaaatta acattttttc gcggccctta tacttcttca
     9181 cgatagaggc aatccctacg tcaagagcac cagttttgtt gacaatgcca aggaaaccac
     9241 caaccataag gatgaagaag gctacatcaa tcgctgcgct cgtttcttta atgagcgaac
     9301 cttcctctgg atgagtacct agcatagccc gaatcggtgc catgaggaca tcccaaatcc
     9361 cttgtggatt ttgaggctga gtctcgtaaa taccttctat aaaggccccc gcagggataa
     9421 accaagttag tactgccata atagcaatga ttatcaataa tacggtgtaa gatgaaggca
     9481 tcttaaaccc ttttttagct ttttcactca tttgtttttc ctcctgatgt ctaacaaagt
     9541 gtaaaaaacc aactactttc ttaaataaac atttaagaaa acgctttcta tttatatttg
     9601 ttttaccata ttaaagtcta aaaaactaat atcttttgaa atattgtaca tgttttcaag
     9661 aataatttct aatttgatat aaagatacta gaaatagaat acatcttatt agtaaaacaa
     9721 cttatccttt ttcaataatt gttccgcttt cagattcaat caaggcgcct agattttcaa
     9781 gggaagtaat aactgctttt ccttctggac gaccattgac aaaagcgata gctgcttcta
     9841 cttttggaag catgctacct ggtgcaaact gatcttgttt gatatattct tccagctggg
     9901 caacattcac atgttccaat ttttcctggt ttggcttgtt gtagttaaca aatacataat
     9961 ctacacctgt caaaacgatg aagaggtctg catcaaccaa ttctgccaaa cgttgggaag
    10021 cgaagtcttt atcaataacc gcttcgacac cagtcaaatg tccattgttt tctttgatga
    10081 cgggaatacc gccaccacct gcagctacga cgacttgacc attatttaaa agagtacgga
    10141 tggtttcaat ttctttgatg tcaacaggtt ttggtgaggc aacgacctta cgccagccac
    10201 ggccagcatc ttccttgaaa gtcgctccgc tcttttcggc ttctgctttt gcttcttctt
    10261 ctgaatagaa aggaccgatt ggtttactca agttaacaaa agctggatca tttttatcta
    10321 cgacaacttg cgttacaaca gaggcaacat ttttttcgat gccttcatcc aagagagcat
    10381 tttgcaaagc atttttcaac cagaaaccga tgctaccttc tgtcatagcg acaagtgagt
    10441 cgagtgggaa ggcagggttc ttttcagagt ctgatgccaa atgttggagc aagagattcc
    10501 caacttgagg tccattaccg tgagtgataa tcagatcatc tccattttta atcaatttta
    10561 caagatgctt agctgtttca actaaagctt cttgttgagc ctttgctgat gggtcagaag
    10621 aaagaatcgc atttcctccc aaagctacta caattttacg atttgccata aattctcctt
    10681 tatcacactc aatagaatgc gtttagattt caatttaatg atttttcaca tattttataa
    10741 gaaataatag attaccatta cataaaagag gaccggacta aagctattag tcgcagccct
    10801 catagctgtt ggtagacggt ttattatcta aaattatact ttaggaatat aaaggttacc
    10861 aagtgtagca gccataacag ctttgatagt gtgcatacgg ttttctgctt gatcgaagtg
    10921 gcgagcgtac ttgctgcgga agacttcgtc tgttacttcc atttcttcta caccaaattt
    10981 ttcagcaacg tctttaccat aaacagtgtg agtatcgtgg aatgctggca agcagtgtag
    11041 gaagatcaag ttttcattgc ctgctttttt aactaagtcc atattgactt ggtaaggttt
    11101 aagaagagct acacgttctg cgaatttgtc ttcttcaccc attgataccc aaacgtctgt
    11161 gtaaagaacg tctgcatctt taactgcttc atcagcatct tcagtgatga gaacatgtgc
    11221 gccactttct ttagcaaatc cttctgccaa ttcaacgatt tctttttctg ggaagagttc
    11281 ttttggtgag aagatgtgaa cattgacacc aaggatagca cctgttacga gcaagctgtt
    11341 ggcaacgttg ttacgtccat caccacagta taccaatgtc aagccttcca agcgaccgaa
    11401 gttttcttga acagtcaagt agtcagcgag catttgagtt gggtgccatt cgtcagttag
    11461 accgttccat actggaacgc ctgagaattc tgccaattct tcaaccatac gttggctgaa
    11521 tccgcggaat tcaatcccgt caaacatacg tcccaatact ttagcagtat cttcagtaga
    11581 ttctttttta cccaactgaa tatcatttgc tccgaggtat tctgggtgag caccaaggtc
    11641 gatagccgca gttgtaaagg ctgcacgagt acgagtagat gttttttcaa ataggagagc
    11701 gatattcttg ccagcaaggt agtggtgttg aatattgcgt tttttcaaat ctttcaagtg
    11761 agctgaaaga ccaataaggt attctaactc tgcacgggta aagtcttttt ctgctaagaa
    11821 gctgcgtcct tggaatactg aatttgtcat tttattattt cctctttcta ttttttacat
    11881 tttctattga cgaataccga acagcgatta cacttcttca cgttcaaatg gcatagacat
    11941 acaacgaggt ccaccacggc cccgaaccaa ttcacttccg cgaatcttaa tcaagcgaag
    12001 cccgtattct tccaaaatct tattggtcac ggtattgcgg tcataaacaa ctaccacacc
    12061 aggtgcgatg gtcaaagtgt tagaaccgtc gttccattgt tcacgcgcag ctgctacgat
    12121 attgccacca ccgcaacgaa tcaaatgaac tttttctaca ccaaggtttt gagcaagaag
    12181 ttcagctaag tcacctttct cttcaactat tttaagtttt tcgttttcgt aagtaactga
    12241 gtaaacgtga aggtcgcctt cgatttctgg gtgaatagtg aacttgtcat agtctaccat
    12301 agtgaagaca gtatccaagt gcatgaattt acggttgtta gcaaattcaa aggccaaaac
    12361 tttcttgaag ccaacatttt tcttgaagat gttgaccaaa agtttttcga tagaagctgc
    12421 gtctgtacgt tgagagatac ctactgcaag gacgtcttta gaaagaatta gctcgtctcc
    12481 accttcgata cgcgtatctt cttcacggtt gtagaccaaa tccacttttc cgccatagat
    12541 tgggtggtat ttgaagatat acttaccgta aagtgtttca cggttacgag tatctgcaaa
    12601 catgtggtta agcgatacgg cgtttccaat tgttgcaaat gggtcgcgag tgaaatagag
    12661 gtttggcatc gggtcaattg caaatggata ctctgattca actaagtcag ttagatcttt
    12721 agcttcgtca ggaatttctg gcaattcaac tttttgaatc ccagccattg ttttttcaac
    12781 caattcttgg ttgtccttga tgccgtgaag taattcacga atagcaacct tggtttgacg
    12841 atcacggatg ttggcttcgt ctaagtattc ctcgataaat tgatcgcgga tttctggaga
    12901 ggtcaatgat tcagcagcga gttgttctag gtagagaacc tcaattcctt catcgcgaag
    12961 agcttgggca aatgcatcat gttctttttg agcatcttcc aagaaaggaa tatcatcaaa
    13021 aagaagcctt tcaagatagt ccggcaataa gttttctaac tccttgcctg gacggtgtaa
    13081 cataactttt ttcagtttcc caatttctga gaagacctga attggatgtg aagacatgta
    13141 ttttcctcct taaaaatttt gacttggcac cattttgggt accgcttaca tgtatgttat
    13201 aacgcaattc ctaggtaatg tcaatggcta taatttctcg gaaaataata taaattatga
    13261 tatttagcac aattttatgt tattatacac aacataggat ggaatacata tatacaaatg
    13321 cataaacttc tattaaagag gatataaaat ttttttaaaa aatttttcaa aaaatacaca
    13381 aataaccaaa aagtgtccaa ttatcatctg gttatcactt ggatctgtat aaagagaaat
    13441 gtttgtgtga aaggataaaa agatgcaaca ttcttttgaa gatagatttt ggagaagcat
    13501 ttcttgttca attgtacaaa ttatagaatc ttttctgagt atttaggaag agataattat
    13561 cttattgacc ctctttttat tttttgttat agtcgacgag gtgatagttt agaataatca
    13621 cttattcaca atctgtggaa aagtctggag agtgaatggt cttcacacaa tgacctgaaa
    13681 gaagcctgag aataattatg gagagtagca ttctgagagg tgttagcaga accatatgac
    13741 agagctgttt gaagagggaa tattgaggag caaaatcctg agcctaccag ttggagttgg
    13801 aaagagctgg ctgttagatc atggtttatt atccacaacc tgtggataac cttgtgaaca
    13861 agagaagttg ctaaagaagg agatatataa cgatgaagaa aatcaaaccg catggaccgt
    13921 taccaagtca gactcagcta gcttatctgg gagatgaact agcagctttt atccacttcg
    13981 gtcctaatac cttttatgac caagaatggg ggactggaca ggaggatcct gagcgcttta
    14041 acccgagtca gttggatgcg cgtgagtggg ttcgtgtgct caaggaaacg ggcttcaaaa
    14101 agttgatttt ggtggtcaag caccacgatg gctttgtcct ttatccgaca gctcacacag
    14161 attattcggt taaggtcagt ccttggagga gaggaaaggg cgacttgctc cttgaagtat
    14221 cccaagctgc cacagagttt gatatggata tgggggtcta cctgtcaccg tgggatgccc
    14281 atagtctcct ctatcatgtg gaccgagaag cggactacaa tgcctattat ctggctcagc
    14341 tgaaggaaat cttatcaaat cctgcctatg gaaatggagg gaaatttgct gaggtttgga
    14401 tggatggtgc cagaggagag ggcgcgcaaa aggttaatta tgaatttgaa aaatggtttg
    14461 aaaccattcg tgacctgcag ggcaattgct tgattttttc aacagaaggc accagtatcc
    14521 gatggattgg aaatgaacga gggtatgcag gtgatccact gtggcaaaag gtgaatcctg
    14581 ataaactagg aacagaagca gagctggact atcttcagca cggggatccc tcgggcacga
    14641 ttttttcaat cggagaggca gatgtttcca tccgtccagg ctggttctac catgaggatc
    14701 aggatcctaa gtctctcgag gagttggtcg aaatctactt tcactcagta gggcgaggaa
    14761 ctccactctt gcttaatatt ccgccgaatc aagctgggct ctttgatgca aaggatattg
    14821 aacgacttta tgaatttgtg acctatcgca atgagctcta taaagaagat ttggctctgg
    14881 gagctgaggt atctggtcca actctttccg cagactttgc ttgtcgccat ttgacagacg
    14941 gccttgagac cagctcttgg gcaagcgatg cagacttgcc catccagtta gaactcgact
    15001 taggttctcc taaaactttt gatgtaattg agttgagaga agatttgaag ttaggccaac
    15061 gtatttctgc tttccatgtg caagtagagg tggatggtgt ctggcaggaa tttggcaggg
    15121 gcttcacagt tggtcataag cgcctcttgc gaggtccgct agtagaggca cagaaggtgc
    15181 gcgtgatgat taccgaggca caatctattc ctgtattgac caagatttcc ctttataaaa
    15241 ctcctggatt atcaaaaaaa gaagttgttc aggaactagc atttgcagaa aaaagcctag
    15301 ctgtggcaaa gggagagact cttcatttta ggattgaacg tagtgaaagt agctcctctt
    15361 tagaggctaa gatttcgatt caaccgggga caggtgtcca tggtgtcgcc tatcaggatg
    15421 agattcaagt ccttgcgttt caagctggtg agactgaaaa aagtctgacg ctaccaacct
    15481 tgtatttcgc aggagataaa accttggatt tctatctgaa cctaacggtg gatggtcagc
    15541 ttgtggatca acttcaagtc caagtttcat aaaagaagaa cctttgcgcg atgcaaaggt
    15601 tcttttggtt attagtgact tggtaaccag ctgagggtga aagttagttg ttcagctttt
    15661 aagaggtctt ggtgttgaat agttgatacg agtgttttgt ccagtcggca ttctttgaca
    15721 aagttaaaat ggttgtggtt ttgtttagta tggatatcca gccatttatc ttctttagcg
    15781 aggtagactc gtagatggtc aaagagaggg attccgaggt catagcttgg ttttcctgga
    15841 caggttggat aaaatccgag agctgaccag atgtaccaag cagagagact accattgtct
    15901 tcatctccag gataggcttc ccaacttggg tgaaaagctt tctgacggag cgtcttgata
    15961 agaagggcag tgtagtcagg gtaatcgctg taacggaaga gataaggaat gtggaaacta
    16021 ggctggttgg aaatggctat ttgtccaaaa ggagcagtag ccatctcgct catttcgtga
    16081 atttcgtaac catagcctgt tatttcaaag aggggagcat cttgacaggt tttcaaaaga
    16141 tagttgctaa aggtttcttt tccacccatc agttggatta agccagggat gtcgtggaga
    16201 acgcctaaag tagcttgaat ggcagagcat tcagcgtagt ctcgccccca actataagga
    16261 gagaagtcag ggtgaaagtt tccttgattg tctcgtgctc gcatgtaacc tgtctcagcg
    16321 tcaaatagct ggcggtaatt ttgtgaagca gccttgtagg tttcagcgat ttctatgttc
    16381 tctagttttt tggcacagct ggcgatacaa aagtcactat aggcatagtc tagagtatgg
    16441 ctaacacttt catggtggtc ggtagagagg taacctagtt cttggtattg ggctagtccg
    16501 tggcggccat tgattccgag agggtcggct ttgctggctg tttcgagcat ggcttggaag
    16561 agttctcctt ctaggtcggg ggccatgtcc ttgcaggtgc tatctgcgat aataccgtct
    16621 aaaagtgtac ctggcatcat acctcgttca tctggagcca gccattttgg aaggaaacca
    16681 gtatcgcggt agctattgag gaaaccttct aaaaagcgtt gatagtgctc cggtatgata
    16741 agggcaaaga gggggaaggt ggtgcggaag gtatcccaga aaccattgtt gctaaagagg
    16801 acaccaggct tgacagtacc agtagccaga tccatgtgga tggcttgccc tgactcatca
    16861 acctcataaa aagtctgtgg gaagaggaag agtctgtaga gacagtggtc aaagaaggtt
    16921 cggtcagcct ctcctgtctc tataatgtca aaacgatgga ggagattttc ccaatccgct
    16981 tgggcacttg ctttacagct atcaaaatct tcttgaggta gattgattag agcttgagaa
    17041 ggagagatga aagaagtggc tagttgcatc tcggtttgac tacttgctaa gtcaattcgc
    17101 cagtctccag cttcttggct gatagcaaga atatccgtgt tcatttgcag ggcagtgaac
    17161 atcgttagcg aatttttgtt agtttcagtt ttaccttctt gtcgcagggc aagagtccgc
    17221 ttatctactt gctctactgt cagttcatct gctgcgtgaa gatagaggga gagggctttg
    17281 ccttgctttt gcttcaaacg aatagaagca ccatagcaag tcggtgtgag ctgggtttca
    17341 atctgatagc gcagggagaa aatctttaga taatgaggtt ggaaagaggc cttatcccta
    17401 tcataggaag attggcggtg aaagaggctg tctcccccca gttgactggt gacaggtgtc
    17461 agaaggagcc aagagtagtc cccaatccaa ggactgggct ggtgagttaa tcgaatcccc
    17521 tgaaagatag gcagatgcgg atcaaaaaac caagctccat cctggtcact ggtctggggc
    17581 acaaagtaat tcatcccaaa aggcacgcct gtgtatggca gggtatttcc ccgagaaaag
    17641 gcatgcctat tggtagttcc caagcgggta tcgatggttt caagtagtgg tttcatagtc
    17701 tttcctttag ctgtttttct acattatatc agaaaaagag ggcctttaga aaaggagttt
    17761 caaaaataac tattttgtag aaaaatgact atcatttgtg tatgtatttt ctgtctcaaa
    17821 agctatatac tgaacatgaa acttgtttga aagagggaat tgcacgatga tttattcgaa
    17881 agaaattgtt agagaatggc tagatgaagt agcagagcgg gctaaggacc atccagagtg
    17941 ggtggatgtt ttcgagcgtt gctacaccga taccttggac aatacggttg aaatcttaga
    18001 agatggttca acttttgtct tgactgggga tattcctgct atgtggcttc gggattcgac
    18061 agcccaactc agaccctacc tgcatgtagc taaaagagat gccctcctgc gtcagaccat
    18121 tgcaggtttg gtcaaacgtc agatgacctt ggtactcaag gatccttatg ccaattcctt
    18181 caacatagag gaaaactgga aggggcacca cgagaccgac cacaccgacc ttaatggctg
    18241 gatttgggaa cgcaagtatg aggtggactc gctttgctat cctttgcagt tggcttatct
    18301 cctctggaaa gaaactggcg agactagtca gtttgatgag acttttgtcg cagcgactaa
    18361 ggaaattctc catctatgga cagttgaaca agaccacaag aactctcctt atcgttttgt
    18421 ccgagatacg gaccgtaagg aagacacctt ggtaaatgat ggctttggac ctgactttgc
    18481 agtgacaggt atgacttggt cagcctttcg tccgagtgat gactgttgcc agtatagtta
    18541 cttgattccg tcaaatatgt ttgctgtagt agtcttgggt tatgtgcaag aaatcttcgc
    18601 agcattaaac ctagctgata gccagagtgt tattgctgat gccaagcgtc ttcaggatga
    18661 aatccaagaa ggaatcgaaa actacgctta caccaccaac agcaagggcg aaaagattta
    18721 cgcttttgaa gtagatggcc taggaaatgc cagcattatg gatgatccaa acgtaccaag
    18781 tctactagct gcgccctatc tgggctactg ttcggtcgat gatgaagtgt atcaagctac
    18841 tcgccgtacc attctgagct ctgaaaatcc atatttctac caaggagaat acgctagcgg
    18901 tctcggaagt tctcatacct tctatcgcta tatctggcca atcgcccttt ctatccaagg
    18961 cttgacaaca agagataagg cagagaaaaa cttcttgctg gatcagctgg ttgcctgcga
    19021 tggcggtaca ggtcttatgc atgaaagctt ccacgtggat gacccaactc tctactctcg
    19081 tgaatggttc tcctgggcta acatgatgtt ctgtgagttg gtcttggatt acttggatat
    19141 tcgctaaggg gctcgcttta gctcaaccga ttcttatcag aatcacaagt ttacatttaa
    19201 aacgttaaaa tttaaattta gaatgaggtt ttacttcatg gaaaatgttg ttgtacatat
    19261 tatctcacat agtcactggg accgtgagtg gtacttgcct tttgaaagtc atcgtatgca
    19321 gttggtggaa ttgtttgaca atctctttga tctctttgaa aatgaccctg agttcaagag
    19381 tttccacttg gatggacaaa ctattgtcct tgacgactac ttacaaattc gccctgaaaa
    19441 tcgcgacaag gtccaacgct acattgacga gggcaagctt aaaattggtc ccttttacat
    19501 cttgcaggat gattatttga tttcaagtga agccaatgtc cgcaatacct tgattggtca
    19561 acaagaagct gccaaatggg gtaaatcaac ccagattggc tactttccag atacctttgg
    19621 aaatatggga caagcacctc aaattcttca aaaatcaggc attcatgtgg cggcctttgg
    19681 tcgtggtgtg aagccgattg gatttgacaa ccaagtcctt gaagatgagc agtttacatc
    19741 ccagttttca gaaatgtact ggcagggtgt ggatggtagt cgtgttttag gtattctctt
    19801 tgccaactgg tacagtaatg ggaatgaaat cccagttgac aaagatgagg ccttgacctt
    19861 ctggaaacaa aaattgtcag atgtgcgtgc ctacgcttcg accaaccaat ggttgatgat
    19921 gaacggctgt gaccaccagc ctgtacagaa aaatctgagc gaagccattc gtgtggcaaa
    19981 tgaactcttc ccggatgtaa tctttgttca tagttctttt gatgaatatg ttcaagctgt
    20041 agaaggtgcg cttcctgaac acttatcaac tgttacaggc gagttgacca gtcaggaaac
    20101 agatggctgg tacacacttg ccaacacttc ttcatcccgc atttacctaa aacaagcctt
    20161 ccaagaaaat agcaacctcc tagagcaagt ggtagaaccc ttgactatta tcactggtgg
    20221 acacaaccac aaggaccagt tgacctatgc ttggaaaaca cttttgcaga acgcgccaca
    20281 tgatagtatc tgtggctgta gcgtggacga agttcaccgc gagatggaaa cgcgttttgc
    20341 caaggtcaac caagtaggaa actttgttaa aagtaacttg ctcaacgagt ggaagggtaa
    20401 aattgctacg gataaggctc aaagtgacta tctctttact gtcattaaca caggcttgca
    20461 tgataaggtc gatactgtca gcacagtgat tgatgtggcg acttgtgatt tcaaggaatt
    20521 gcacccaaca gaaggctaca aaaagatggc tgctcttatc ttgccaagtt accgtgtgga
    20581 ggacttggat ggtcgtcctg tagaggctac aatcgaagac ctcggagcta attttgagta
    20641 cgatttacca aaagataagt tccgccaagc tcgtattgct cgacaagtgc gcgtgaccat
    20701 tccagttcac ctagcgccgc tttcttggac aaccttccaa ttgctggaag gaaaacaaga
    20761 acaccgtgag ggtatttacc aaaacggagt gattgataca ccattcgtaa cggtgagtgt
    20821 ggatgacaac atcacagtct atgacaagac aactcacgaa gcctatgaag actttatccg
    20881 ctttgaagac cgtggggaca tcggaaacga gtatatctat ttccaaccaa aaggaacaga
    20941 gccaatcttt gcagagctta agggccacga ggtcttggaa aacacagctt gctatgctaa
    21001 aatcttgctc aaacatgaat tgaccgtgcc tgtcagtgcg gatgaaaagc tagaagaaga
    21061 gcaacaaggt atcatcgagt ttatgaagcg tgaggctgga cggtcagaag aattgacaaa
    21121 cattcctctg gaaactgagt tgactgtctt cgttgacaat ccacaaatcc gcttcaagac
    21181 tcgctttact aacactgcca aggatcaccg tatccgtctc ttggtcaaga ctcataacac
    21241 gcgtccaagc aatgattctg aaagtatcta tgaggtggtg acacgaccaa acaaaccagc
    21301 tgcttcatgg gaaaaccctg aaaatcctca acaccaacaa gcttttgtca gtctgtatga
    21361 cgatgaaaaa ggggtgactg tatccaataa gggattgaat gaatacgaaa tccttgggga
    21421 taacaccatt gccgtgacca ttttgcgtgc atcaggtgag ctaggtgact ggggctactt
    21481 cccaacgcca gaagcacaat gcttgcggga gtttgaagtc gagtttgcac ttgaatgcca
    21541 ccaagcccaa gaacgcttct cagcctatcg tcgtgccaaa gccttgcaga caccgtttac
    21601 cagccttcag cttgctagac aggaaggaag cgtggttgcg actggtagcc tcttgagcca
    21661 ttctgttctc agcataccgc aagtttgtcc aacagccttt aaagtggcgg aaaatgaaga
    21721 aggctatgtc ctccgttact ataatatgag tcaagaaaat gtgcgcatat cagaacatca
    21781 acaaaccatt cttgacttac ttgagcgacc atatccagtt cattcaggac tattggctcc
    21841 acaagagatt cgtacagaat tcatcaaaaa agaagaaatt taatttcaaa aagtaaacat
    21901 caaaagaaag gaggggcgaa aaagtaagaa ctaactgctg attcgcccct ttttatggta
    21961 aaaacaatga ccattgcaac gattgatatc ggagggactg ggattaagtt tgccagtctg
    22021 actcctgatg ggaaaatact ggataagaca agtatttcaa cgcctgaaaa cttggaggat
    22081 ttactagcgt ggctagatca acgcttgtca gaacaggatt acagtgggat tgctatgagc
    22141 gttccaggtg cggtcaatca agagacaggt gtgattgatg gcttcagtgc ggtgccctac
    22201 atccatggct tttcttggta tgaggcgctt agctcttatc agctacctgt ccatctggaa
    22261 aatgatgcca actgcgttgg actcagtgaa ctactagctc atccagagct tgaaaatgca
    22321 gcctgtgtcg tgattgggac agggattggc ggagccatga ttatcaatgg tagacttcat
    22381 cgaggtcgcc acggtctggg tggagaattt ggctacatga caacccttgc ccctgctgaa
    22441 aaacttaata actggtcgca actagcatca actgggaata tggtacgata cgtgattgaa
    22501 aaatctggtc atactgattg ggacggtcgc aagatttacc aagaggccgc agctggtaat
    22561 gctctttgtc aagaagccat tgagcgcatg aaccgcaatc tggcgcaagg cttgctcaat
    22621 atccagtatc tcatcgatcc agatgtcatc agtctgggtg gctctatcag tcaaaatcca
    22681 gattttatcc aaggtgtcaa gaaggctgtt gataactttg tcgatgccta cgaagaatac
    22741 acggtcgcac cagttatcca ggcctgcacc tatcacgcag atgccaatct ctacggtgcc
    22801 cttgtcaact ggctacagga ggaaaagcaa tggtaagatt tataggactt agtcccaaac
    22861 aaacgcaagc tattgaggtt ttaaaaggtc acatttctct accagatgtg gaagtggctg
    22921 tcactcagtc tgaccaagcc tctatctcta tcgagggtga ggaaggtcac tatcaattga
    22981 cctaccgcaa acctcaccaa ctttatcgtg ccttgtcctt gttggtaaca gttctagcag
    23041 aagctgataa agtagagatt gaggaacaag cagcttatga agatttggct tatatggttg
    23101 actgttctcg aaatgcggtg ctgaatgtcg cttctgccaa gcagatgatt gagatattgg
    23161 ctctcatggg ctactcaacc tttgagctct acatggaaga cacttaccag attgaagggc
    23221 agccttactt tggctatttc cgtggagctt attcagctga ggagttgcag gaaatcgaag
    23281 cctatgccca acagtttgac atgacctttg taccatgcat ccagaccttg gcccacttgt
    23341 cggcctttgt caaatggggt gtcaaggaag tgcaggagct ccgtgatgta gaggacattc
    23401 ttctcattgg cgaagaaaag gtttatgacc tgattgatgg catgtttgcc acgttgtcta
    23461 aactgaagac tcgcaaggtc aatatcggga tggacgaagc ccacttggtt ggtttgggac
    23521 gctacctgat tttgaacggt gttgtggatc gtagtctcct catgtgccaa cacttggagc
    23581 gcgtgctgga tattgctgac aaatatggtt tccactgcca gatgtggagt gatatgttct
    23641 tcaaactcat gtcagcggat ggccagtacg accgtgatgt ggaaattcca gaggaaactc
    23701 gtgtctacct agaccgtctc aaagaccgtg tgactctggt ttactgggat tattatcagg
    23761 atagcgagga aaaatacaac cgtaatttcc gcaatcatca caagattagc catgaccttg
    23821 catttgcagg gggagcttgg aagtggattg gctttacacc tcacaaccat tttagccgtc
    23881 tagtggctat cgaggctaat aaagcctgcc gtgccaatca gattaaagaa gtcatcgtaa
    23941 cgggttgggg agacaatggt agtgaaactg cccagttctc tatcctatca agcttgcaaa
    24001 tctgggcaga actcagctat cgcaatgacc tagatagttt gtctgcgcac ttcaagacca
    24061 atactggtct aacggttgag gattttatgc agattgacct tgccaacctc ttaccagacc
    24121 taccaggcaa tctcagcggt atcaatccca accgctatgt tttttatcag gatgttcttt
    24181 gtccgatact tgaccgacac atgacacctg aacaggacaa accgcacttc gctcaggctg
    24241 ctgagacgct tgctaacatt aaagaaaaag ctggaaacta tgcttatctc tttgaaactc
    24301 aggcccagtt gaatgctatt ttaagtagca aagtagatgt gggacgacgc attcgtcagg
    24361 cctaccaagc ggatgataaa gaaagtttac aacaaatcgc cagacaagaa ttaccagaac
    24421 ttagaagcca aattgaagac ttccatgccc tctttagtca ccaatggctg aaagaaaaca
    24481 aggtctttgg tttggataca gttgacatcc gtatgggcgg actcttgcaa cgcatcaaac
    24541 gagcagaaag ccgtatcgag gtttatctgg ctggccagct tgaccgcatc gacgagctgg
    24601 aagttgaaat cctaccattt actgacttct acgcagacaa ggatttcgca gcaactacag
    24661 ttaaccagtg gcataccatt gcgacagctt cgacgattta tacgacttaa tactcttcga
    24721 aaatctcttc aaaccacgtc agcttccatc tacaacctca aaacagtgtt ttgagcagcc
    24781 tgcagctagc ttcctagttt gctctttgat tttcattgag tataaaaaca agaacatctt
    24841 gcttggcgca gggtgtttcg cgtgaaacag aagaattatc tggtttcaaa tgctacagtt
    24901 agacaaactt atgataaaat agcagaaagt gaatgtttcc taagagcaat tctatcgatg
    24961 agcaattgga ggtattatgc tacacttaaa attagtaaaa caagaaatag aagctgaaaa
    25021 gccagcatct gtagaagctt ggatcatttc cgtcaaatta aaaaaggtta ctaccgacat
    25081 atatagattc caaaaacaaa aacgttagcg gaactagcag atgtgatttt atggagtttc
    25141 gattttgtaa atgatcatgc tcatgcattt ttcatggata atgttgagtg gagtcatgca
    25201 gattcttact ttcttagctt tgttagtgac gatgttgaag aacgttacca gaacaatatc
    25261 tagattatga tggttttgac tatgaagaat ggtaaaattg aaatcagtct gtgtaggctt
    25321 agtatttcaa tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca
    25381 atcaaattca ttcgtaatcc gaagcgttta cgatgatttc gatagattgt tgaaaacatt
    25441 ttaaacgttt ttactttggc aaagatgttc tcaaccttgc ttctctcctt ggatagcgca
    25501 tggttacagg ctttatcttc agctgttagc ggcttgagtt tgctggattt acgtggagtt
    25561 tgtacttgag gatatatctt catgagtcct taataaccac tgtcagccaa gattttacca
    25621 gcttgtccga tatttctgcg actcattttg aacaacttca tatcatgaca atagttcaca
    25681 gcgataacca aagaaacaat tctcccttga cttgtgacaa tcgcctgagc cttcatagcg
    25741 tggcatttct ttttacttcc gtcacatcaa tcattaccgt gtcctcagag ctgagaggag
    25801 ttcttgaaat cgtaacacca ctttgaacaa gagttacttc aacccattgg ctccgacgga
    25861 ttaagttgct ttcgtgaata ccaaaatcgg ccgcaatttc ttcataagtg cggtattctc
    25921 gtacatattg aagagtggcc ataagaaggt cttctaggct taatttaggt tttcgtccac
    25981 cttttgcgtg tttaagttga taagctgttt ttaatacagc taacatctct ttaaaagtcg
    26041 tgcgctgaac accaacaaga cgcttaaatc gtgtatcagt taattgttta cttgcttcat
    26101 aatttcgcag ggagtctatt gactctttgg taggtgtcaa tgtttttttc atctatcccg
    26161 agaattattt tcccgccatt tgtatttgca aatgctgagt aggtttccca gaaagactct
    26221 ggaagattgt ttttagcttt tttgtattct aaatcaaccc cttcaaattt taagtccata
    26281 tttttccttt acatctgttt tttgtggttc tggtatttgt taaagttgag tgataatata
    26341 gcgaattgaa tttcgagagt ttttactcag ttaatttctt ttttaaccca ctttaatttc
    26401 ttttttaaca cgggttaaaa aagaaattaa agtgggttaa ttttccttga cttaaaattt
    26461 aaaaatgata tactgtgttt atggagagat gacaatttat aaaatgtact actctattct
    26521 actagataat gattgaataa aactttttat aacaacggct agcaaagtta taattttata
    26581 tctattagaa aataaatatg taaggaaatt taaatgaaaa aaactacaat attatcatta
    26641 actacagctg cggttatttt agcagcatat gtccctaatg aaccaatcct agcagatact
    26701 cctagttcgg aagtaatcaa agagactaaa gttggaagta ttattcaaca aaataatatc
    26761 aaatataagg ttctaactgt agaaggtaac ataggaactg ttcaagtggg taatggagtt
    26821 actcctgtag agtttgaagc tggtcaagat ggaaaaccat tcacgattcc tacaaaaatc
    26881 acagtaggtg ataaagtatt taccgttact gaagtagcta gtcaagcttt tagttattat
    26941 ccagatgaaa caggtagaat tgtctactat cctagctcta ttactatccc atcaagcata
    27001 aaaaaaatac aaaaaaaagg cttccatgga agtaaagcta aaactattat ttttgacaaa
    27061 ggcagtcagc tggagaaaat tgaagataga gcttttgatt tttctgaatt agaagagatt
    27121 gaattgcctg catctctaga atatattgga acaagtgcat tttcttttag tcaaaaattg
    27181 aaaaagctaa ccttttcctc aagttcaaaa ttagaattaa tatcacatga ggcttttgct
    27241 aatttatcaa atttagagaa actaacatta ccaaaatcgg ttaaaacatt aggaagtaat
    27301 ctatttagac tcactactag cttaaaacat gttgatgttg aagaaggaaa tgaatcgttt
    27361 gcctcagttg atggtgtttt gttttcaaaa gataaaactc aattaattta ttatccaagt
    27421 caaaaaaatg acgaaagtta taaaacgcct aaggagacaa aagaacttgc atcatattcg
    27481 tttaataaaa attcttactt gaaaaaactc gaattgaatg aaggtttaga aaaaatcggt
    27541 acttttgcat ttgcggatgc gattaaactt gaagaaatta gcttaccaaa tagtttagaa
    27601 actattgaac gtttagcctt ttacggtaat ttagaattaa aagaacttat attaccagat
    27661 aatgttaaaa attttggtaa acacgttatg aacggtttac caaaattaaa aagtttaaca
    27721 attggtaata atatcaactc attgccgtcc ttcttcctaa gtggcgtctt agattcatta
    27781 aaggaaattc atattaagaa taaaagtaca gagttttctg tgaaaaaaga tacatttgca
    27841 attcctgaaa ctgttaagtt ctatgtaaca tcagaacata taaaagatgt tcttaaatca
    27901 aatttatcta ctagtaatga tatcattgtt gaaaaagtag ataatataaa acaagaaact
    27961 gatgtagcta aacctaaaaa gaattctaat cagggagtag ttggttgggt taaagacaaa
    28021 ggtttatggt attacttaaa cgaatcaggt tcaatggcta ctggttgggt taaagacaaa
    28081 ggtttatggt attacttaaa
//
LOCUS       DAVHSI010000026        27419 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.026, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000026 DAVHSI010000000
VERSION     DAVHSI010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.026"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(55..1284)
                     /locus_tag="VVR21_001319"
     CDS             complement(55..1284)
                     /locus_tag="VVR21_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU6055196.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISHDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(1274..2440)
                     /locus_tag="VVR21_001320"
     CDS             complement(1274..2440)
                     /locus_tag="VVR21_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6055197.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            2584..3597
                     /locus_tag="VVR21_001321"
     CDS             2584..3597
                     /locus_tag="VVR21_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU6055198.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(3642..4061)
                     /locus_tag="VVR21_001322"
     CDS             complement(3642..4061)
                     /locus_tag="VVR21_001322"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU6055199.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(4072..5478)
                     /gene="atpD"
                     /locus_tag="VVR21_001323"
     CDS             complement(4072..5478)
                     /gene="atpD"
                     /locus_tag="VVR21_001323"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU6055200.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(5564..6442)
                     /locus_tag="VVR21_001324"
     CDS             complement(5564..6442)
                     /locus_tag="VVR21_001324"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU6055201.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(6458..7963)
                     /locus_tag="VVR21_001325"
     CDS             complement(6458..7963)
                     /locus_tag="VVR21_001325"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU6055202.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(7978..8514)
                     /locus_tag="VVR21_001326"
     CDS             complement(7978..8514)
                     /locus_tag="VVR21_001326"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU6055203.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(8514..9008)
                     /gene="atpF"
                     /locus_tag="VVR21_001327"
     CDS             complement(8514..9008)
                     /gene="atpF"
                     /locus_tag="VVR21_001327"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU6055204.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(9022..9738)
                     /gene="atpB"
                     /locus_tag="VVR21_001328"
     CDS             complement(9022..9738)
                     /gene="atpB"
                     /locus_tag="VVR21_001328"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU6055205.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(9773..9973)
                     /locus_tag="VVR21_001329"
     CDS             complement(9773..9973)
                     /locus_tag="VVR21_001329"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU6055206.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(10048..11001)
                     /locus_tag="VVR21_001330"
                     /pseudo
     CDS             complement(10048..11001)
                     /locus_tag="VVR21_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155340.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11469..11867)
                     /locus_tag="VVR21_001331"
     CDS             complement(11469..11867)
                     /locus_tag="VVR21_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055207.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            11989..12069
                     /locus_tag="VVR21_001332"
                     /pseudo
     CDS             11989..12069
                     /locus_tag="VVR21_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(12600..13082)
                     /gene="greA"
                     /locus_tag="VVR21_001333"
     CDS             complement(12600..13082)
                     /gene="greA"
                     /locus_tag="VVR21_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU6055208.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(13153..14808)
                     /gene="mltG"
                     /locus_tag="VVR21_001334"
     CDS             complement(13153..14808)
                     /gene="mltG"
                     /locus_tag="VVR21_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU6055209.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPAIETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(14889..15383)
                     /locus_tag="VVR21_001335"
     CDS             complement(14889..15383)
                     /locus_tag="VVR21_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055210.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(15380..15844)
                     /locus_tag="VVR21_001336"
     CDS             complement(15380..15844)
                     /locus_tag="VVR21_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055211.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(15854..17188)
                     /locus_tag="VVR21_001337"
     CDS             complement(15854..17188)
                     /locus_tag="VVR21_001337"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU6055212.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAIYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(17199..17816)
                     /locus_tag="VVR21_001338"
     CDS             complement(17199..17816)
                     /locus_tag="VVR21_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6055213.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(17864..20962)
                     /locus_tag="VVR21_001339"
     CDS             complement(17864..20962)
                     /locus_tag="VVR21_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU6055214.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDILLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFESDFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(21055..22221)
                     /locus_tag="VVR21_001340"
     CDS             complement(21055..22221)
                     /locus_tag="VVR21_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6055215.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(22229..23323)
                     /locus_tag="VVR21_001341"
     CDS             complement(22229..23323)
                     /locus_tag="VVR21_001341"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU6055216.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDTRDLIADLRQALEG"
     gene            complement(23481..24602)
                     /locus_tag="VVR21_001342"
     CDS             complement(23481..24602)
                     /locus_tag="VVR21_001342"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055217.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETSFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIY
                     SSSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKIAFVGPSGSGKSTIVRLLERFYKPLSGYILMEQSSIYDFNLKEWRSKIAWVSQNNA
                     VLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGR
                     SQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVK
                     DVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(24611..25156)
                     /locus_tag="VVR21_001343"
     CDS             complement(24611..25156)
                     /locus_tag="VVR21_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055218.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            complement(25328..27286)
                     /locus_tag="VVR21_001344"
     CDS             complement(25328..27286)
                     /locus_tag="VVR21_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6055219.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
BASE COUNT         8033 a         6025 c         5010 g         8351 t
ORIGIN      
        1 aaaaaccgta gctatcaaaa gagataaact acagttctat atgtttaaac attcttacaa
       61 tctctcaaac agttcttgca tttgcacatc atctggaacc agttttaagt aagtgtgagc
      121 atggactttt gcttcttcaa aatgtcccaa ttcacgcaag agatagatat agtgttccag
      181 aaattctgga ttgtccttca aatctcctgt caactcttga taatgctcat aagcagtatc
      241 caaatcgtcc atttcttgat aagaacgagc aatcatccac ttggtcaaaa gattttctgg
      301 ctcctcactc tgcaagtcta gaatatcctc ataacgctcc tgctccagat aaatagtggc
      361 taaacgaagc aagatttctt ctgtatcctc agcgtcttct tttgcagcaa gaagataatt
      421 ttctgcacca ctagcatcat gcaattcata agaaaattgt gaagcagcta gcaagaggcg
      481 agtttcaaag ggatttttct ctaatccttg cttagcgata cgcagggctt cttgaacttg
      541 atgttcctta tgtaaagcct gactgtaccc atactcatag ccttcaaagt catgagaaat
      601 ggtatcaagc tgcttaaagt agagggtggc tttttgatat tcttcttgat caaaataaag
      661 actggccaac tcaaaagctg ttaagtcatc gtattctaac tccagggctt tttctaaaaa
      721 ctcagtagcc gtttcaaatt tccctaactg agcataggca aagccaattc gttgataggt
      781 ggaaatgccc gtttgctcat aaatcgagcg attatctaac tgggcatagg cttgaatagc
      841 cgcttggtaa ttttccaact cactatccaa ctctgccaaa cccaatatca agagagaatc
      901 ctctgagtag gtcaaggcct ccaataattt ctcacgtgcc acatctgtca aaccttccag
      961 ctggtaaagg tctgccttca gagccaaaga cgagacatac cagtcactgt cagcttggat
     1021 ttcctcaaga taggtaaagg cttcttctat ttgaccatcc tcgctagcaa ttgcagctag
     1081 attaagatga acctctggaa aatcctctac aattttcagg taaatttcct tggcctgagg
     1141 atagaaacca atcccttcaa gataagttgc caactcatac agaagatcac ttgaatcatt
     1201 ttctaaagct ttggcgaaat aatgctcagc cttagttaaa tcttgctcct ccaaagcctg
     1261 taacatctgt tgactattgt tcactcttga cttcctcacc ctctaattca tatagaccac
     1321 tgactacctt ataccattcg aaaatggctg aaatgacaac cttagcagag gcataaaccg
     1381 gaataccaag taaaactccc cagataccaa acatagatcc tgaagttaac aaaacaaaga
     1441 gaacattaat aggatggatg tttaattgac ttcccaaaat caatggagag acaaaacggc
     1501 cttcaatagt ttgttctacg ataaagacaa tcactacttt caaaagcatg actggaccag
     1561 caatcaaacc caatactaga gcaggaagca tggctagaaa gctaccaaga taagggacca
     1621 gatttaaaat accagcagta acccccagcg taaccgcata gcgtagacca ataatcttga
     1681 agaagatgat aaacattact gctacaataa tagccactgt cacttgccct cgaacatagt
     1741 tggacaactg ttgattcaca tctgatagaa cttgtccaac aggttccttc aattttcttg
     1801 gaatgaattg ggtcaaatag ttacgcaagc ctttcccatc acgcaagaga taaaagagca
     1861 tgaaaggaac gataatcaag gcaacaatca cttgagaagc tccgctaata aaggcactca
     1921 cccagttgac tgcctgagat gaaaccttac ttgccaaaac tgtagcctgg ctagaaaaat
     1981 tggtcaaaac ttgctctaat tgaggtctga aatcatctgg caggtgctgg gctaccaatc
     2041 cattaacaat cctatctata tcttctaagt aaacaggaac gtttcttgca aaggtcaaaa
     2101 cctgacgttg cagatttgga atggcgactg ccaagcccca aatgataaag agagcgatga
     2161 taacaaagac aatagtgata gctataacac gattaacctt atgcttctcc atccaatcaa
     2221 caataggatt caacaaataa tataacaaac cagacaaaat gactggcaac atcacaactg
     2281 ctaaaaagtc taaaacaggt gaaaatagaa aactaatctt acttaaaata aaaagattca
     2341 gtcccaataa taaggttact aaaaataccg taattgcctt gttatctaaa aaccacttga
     2401 aaaaccaaga taggctaaaa tgtttctctt tttgctccat aaatacttcc tttctattgt
     2461 tctctcatta taccattttt gaaacaaaat aactcttttt taaagtgctt acatctaatt
     2521 ggatatcttt aatttacttg tttttgtgat ataatagtct tatctttaca cagaggtata
     2581 gtaatgaaag aaactgttta ttttggaact tatacacgtc gtacttctca agggatttac
     2641 aaggcagact ttgatacaga aactggtcag ctttcaaatc tagaactttt tgcagctgag
     2701 ccaagtccaa cctaccttgc ctttgaccag caccaacatt tatacactgt tggtagccaa
     2761 gacgataagg ggggaattgc agcctatcaa actgacggga ctgtgttaaa tcatgttgtt
     2821 gaagaaggag ctccccactg ttatgttgct gtcgatgaaa agcgtgattt ggtttacgca
     2881 gccaactatc acaagggaca agtccttgtt tataaacgcc aggaagatgg tagtcttcta
     2941 cttagtgata tggatcaaca cagtggccaa ggtccacatg aaaatcaagc ttccccccat
     3001 gttcactata cagatttaac acctgaccac tatctagtga cctgcgactt gggaactgac
     3061 caagtcatca cctatgacct cgatcaagaa ggaaaattat ctaagctcta tacctatcac
     3121 agcaagccag gagcaggctc acgccatatc attttccata accactataa aatcgcttat
     3181 ctcatttgtg aactcaatag tactatcgaa gttttaatct acgatggcgt tggcgaattt
     3241 gaacgtatgc aggttatttc aactttacca gaagcttacg aaggctttaa tggaaccgct
     3301 gctattcatc tctctaaaga cggtaaatac ctctacgctt ctaaccgtgg ccatgattct
     3361 atcgcagtat ataccatcct tgcggacggt agcttagagt tattagaaat cgttccaacg
     3421 catggtcaga ctccacgtga ttttgatttg acacccgacc aaaaatttct cattgttgtc
     3481 catcaagact ctgacaatgc aactgtcttt aaacgtaatt gtgacaatgg tcgtctagca
     3541 gaactctcca acgacttcca tgttcccgaa gcagtctgca tccgttttgc tccttaaaac
     3601 accataaaaa atgaacttgg tattttcaag ttcatttttt cttatagtct atttccgaca
     3661 ttaatacggt taatggcacg ttgcaaagca atcttagcac gacgttcttg gtcaatcaaa
     3721 tgtttgtctt gtgcttcttc aattgcacgt tctgcacgaa gtttggcacg ttctgcacgg
     3781 ctaatatcga tatcacgagc acgttctgca gagtcagcga cgattgtgat catatcattg
     3841 gcaatttcaa taacgccacc gtttactgca atccagttca cgtgatcttt atcatcgata
     3901 cgttttacct ttacttcatc aactgctaaa accgcaatca tattttcatg tcgtggcaag
     3961 atccccatct caccatccag agttcgaacc gatacatagc tggcatggtg atcatagacg
     4021 agaccatctg gtgtcacgat ctggacagtt aactgagcca taggtcacct cttaaaatcc
     4081 cattttttca gcttttgcaa tcacatcttc gatagaacct acaccacgga aggcatcttc
     4141 tggcaagtgg tcgtatttac catcaaggat ttccttaaag ccacgtacag tttcagcaac
     4201 tggaacataa gaacctggct gaccagtaaa ttgttccgca acgttgaagt tttgtgacaa
     4261 gaagaactgg atacgacggg cgcgagcaac caaggtcttt tcttcatcag aaagctcatc
     4321 cataccaagg atagcaatga tatcttgcaa ttcatggtaa cgttgaagga cacgttttac
     4381 ttcagcagca actgcatagt gctcttctcc aacgatttca ggtgccaagg cacgtgagct
     4441 tgaagcaagt gggtcaacgg ctgggtagat acccaattgt accaatttac gttccaagtt
     4501 tgttgttgaa tccaagtgag cgaaggctgt tgctggcgct gggtcagtat agtcatccgc
     4561 tggcacatag atagcctgga tagaggttac agaacccttc ttggttgatg tgatacgttc
     4621 ttgcaattga cccatttccg tagcaagtgt tggttggtaa ccaacggctg atggcatacg
     4681 acccaaaagg gcagatactt ctgaaccagc ctgagtgaaa cggaagatat tatcgataaa
     4741 gagaagcacg tcttggcctt ccacatcacg gaagtattca gcgattgtca aaccagtaag
     4801 ggcaacacgc atacgtgctc ctggtggctc attcatctga ccaaagacca tggctgtttt
     4861 ctcgataacg cctgattctt tcatttccca gtaaaggtca ttcccctcac gagtacgttc
     4921 cccaacacca gtaaatactg aaataccacc gtgctcttgg gcaatgttgt gaatcaattc
     4981 ttggattaag acggttttac caactccggc accaccgaaa agtccaactt taccaccttt
     5041 aaggtaaggg gcaagaaggt caataacctt gatccctgtt tcaaggattt cagaagaggt
     5101 agacaactca tcaaaagttg gagctttttt atgaattggc tgacgctctg cgtcttctgt
     5161 aaaaggagct tccaaatcaa tggtatctcc caaaacgttg aagacacgtc ccaaagtttc
     5221 tttacctact ggtacagaga ttggacgacc tgtgtccaat acttccattc cacgagtcaa
     5281 cccatctgtt gattccatgg cgatagtacg aaccatacca tctcctaact ccaaggctac
     5341 ttcaaggacg atttttgttt ttctttcgtc atttttgtag acgacaagtg cattgttaat
     5401 ctcaggaagt ttttcccctg ctgcaaacaa aacgtctaca acgggaccga taacctgagc
     5461 aattttacct gaactcatct ccttctccta ttctatataa gatactgtcg gttcctagct
     5521 caactaggtc ctaagttcat tttcatacga gctggactag agcctattct aaggcactag
     5581 cacctgctac gatttctgta atttcttgtg taatcgccgc ctgtctggca cggttatact
     5641 gaattgtcaa atcattgatg actttcttag cattatctgt cgctgtttgc atggctgtca
     5701 tacccgcagc attctcagct gtcttggcat cgataatggc accgtaaatc atactttctg
     5761 caaactgagg caacaactgc tccagaattt cttctcggct ggtttccaat tcaaaagtca
     5821 agctgtactc ttcatccgct tcatttggat ccaagtcaac aatcggaagc atttgttcca
     5881 cacgcatttg actggttagc gtattgacat ggtggttgta gcaaacataa agctcatcaa
     5941 agagttcatt ttggtacatt tcaacagttt ttgaaataat cttacgaact tgatcaaagc
     6001 taggttggtc tgccaagcca cgtaattcat aaagtggttg aataccgcga gccttaaaga
     6061 aatcagctcc catcccaccg atacagatca tttcaaaacc tttaccgtct gggtggtatt
     6121 cttctttcaa ctccataaca gctttcaaaa tagaggaatt ataacctcca accaaaccgc
     6181 ggtctgaagt gataacgata tagcctgtct tcttcacaga acggctaatc aacatcggat
     6241 tagttgaagc accagctcca ttaccatgaa ggatatctgt caaaagttta cgcactttct
     6301 gagcgtaaac ttggaagttg cgagcagctt cttcagagcg acctagctta gcagccgata
     6361 ccatttgcat ggcattagtg atttgactcg tattttttgt tgaggcgatt tttgttttaa
     6421 tatcatttag agacactgcc atctgacacc tctattctta ttggaagcta gattgattga
     6481 gaaactctgt aatcgcagca tccaagactg cttcttctgg caagtctttt gtatcacgaa
     6541 tggtttccaa aatctctgga tgttgagcat caaagaaggc atggaactct tcctcgaaac
     6601 gaacaatatc atctactgga acagtatcca agaaaccatg tgtcaaagca taaagaatgg
     6661 ttacttgttt ctcaacaggt aatggtttgt gaacaggttg tttcaagacc tcaacggtac
     6721 gacgtccacg gttcaactta gcctgtgttg ctgcgtccaa gtcagaacca aacttagtaa
     6781 aggcttctaa ctcacggtat gaagcaaggt cgatacgaag tgtaccagca accttcttca
     6841 tggctttgat ttgtgcagaa ccacctacac gagatacaga tgaacccgca tcgatggctg
     6901 gacgaatacc tgcattgaag aggccatcgc caaggaagat ttgtccatca gtgatagaaa
     6961 tcacgttggt tgcgatatag gctgagatat ctcctgcttg tgtctcgata aatggtaggg
     7021 ctgtaattga tccaccacca agttcatcag aaactttagc tgagcgctca agcaaacggc
     7081 tgtggagata gaaaacatcc cctgggaagg cttcacgacc tggaggacga cgaagcaaga
     7141 gcgatagttc acgataagct accgcttgtt ttgatagatc atcgtataca atcaaaacat
     7201 gcttaccttg atacataaat tcttccgcca tagcaacccc agtataagga gctaggaaga
     7261 gcaatggaga tggttgtgaa gcagaggctg tcacaacgat tgtgtagtcc aaggcaccgt
     7321 actgacgaag tgtttctact tgcgtacgaa ctgttgattc tttttgtcca atcgcgacgt
     7381 agatacagat catatcttga tctttttggt tcaagattgt atcaatcgca atggttgttt
     7441 tccctgtctg acggtcaccg ataatcaact cacgttgacc acgaccaatc ggtacaaggg
     7501 cgtcaatagc tttcaaacca gtttgcaatg gttctgaaac agacttacgt tgcataacac
     7561 caggagctgg tgcttctact ggacgagttt tatcagtgtg gatttctcca agaccgtcaa
     7621 ctggacgacc aagcggatcc acaacacgac caatcagact ttcacctaca gggacttcca
     7681 tgattttccc tgtacggcgg attgtatcgc cttcacggat atctgtaaag tcacctagga
     7741 tgataatacc aacgtctgtt gactccaagt tttgagccat accataagag ccgttttcaa
     7801 aattcaacaa ctctccactc atgacatttt caaggccatg agcacgcgcg ataccgtccc
     7861 cgatataggt tacaacacct gtttcagtca catcaaaatt gggtttgaaa ttttcaattt
     7921 gttgcttaat taaagcgctg atttcttgtg cgttaattgc caaaagaaca ccactttcta
     7981 tttcaaattt tctttaacaa ctttaagttg ttgtttaata ctcacatcaa ttgtcttgtg
     8041 attggcaaaa atgacaaaac caccaatgag actttcatcg atttgttctt ttacactcct
     8101 tactttcaga gacatttttt tctcaatcaa agggagcaaa cgagtcttct gttcatcagt
     8161 tagaggatga gcagacgtaa tcgtcacttc aaatcgattt gtttcttttt caagtcggtt
     8221 caagcaatct acaagcacat cataaaaaag atttgctctg tgattgtagg ccagaacctg
     8281 gataaagttt tgtaataaag gcgacacaga atcttggaaa aaagcaattg ttttttcctt
     8341 atccgactcg tctactgcca cttgttttaa aaaagaaggc agacctgttt tttcaacaac
     8401 ttgcttgatt tgagtcaagt ctgaaaagat acggtcttct tctccttttt caagtaccaa
     8461 ttggacaaaa ggcatgctgt atttttcaat tacctttact gttttcttgt ccattaagct
     8521 tctcctagct gatcgatata ctgatcaatg agtgctttat gggcatgact gtcaaggttt
     8581 tgtgagatga ttttaccagc taagctgatg gtcaaatctg cgacctcacc cttaacactc
     8641 tgtaaagctt ctactttatt ttgagcaatt tcttgattgg ctttttcttt taagtgtcct
     8701 gcttctagtt tagcatctgc taagatatta gccttacttt gctcagctgt ttcctttgca
     8761 ttttcaatga ttgtcttagc ttctttacgg ctaccagcca attcatcttc gcgtttttga
     8821 gccaatactt ctgctttttg acgggcttct tcagctctgt caatatctga agcaattttt
     8881 tcagctcttt cttcgaaaat gcctgtaata ttagaccatg caaatttttt aatcaagact
     8941 agcaaaagaa taaaagagcc agtgattaaa ataaaattac caattaattc acctactgtt
     9001 acgtgcatca gttactcctt tctattcctc ttcaatatta atcttattcc ctaaatacac
     9061 agatgtcaaa agagtaaaaa cataagcttg gatgcaggaa ataaagacag aaaatgcagt
     9121 ccaagccaaa ttagctccaa aggctactgg ataccaataa atagcttggt gggaaagaag
     9181 aagtaacaaa ctcgtcatga cctctcctgc aaagatattc ccaaaaatcc gcaaagccaa
     9241 agataagaag tttgtaaatt cttccaagat attcatcggt atgacaaaaa caggactcat
     9301 aaaagatttt atactttttt taaatccacg acgacgaacg ctttctatat gtgtcaacaa
     9361 aatgacaaga aaagataagg ttaagtcata ctgtaaatta gcggttggcg aactccacca
     9421 gttagtccca tcgatcgttt gaatctttgt cattaagcca aggttattgg caatcaccat
     9481 gaaaaggaat aaacaaagga aaaagagtga gtaatctttc atgtagcgcg aaccaatgtt
     9541 aggttctgta aatccaataa caaagtcata gacatactca agtacatttt gctttccttt
     9601 gggtttcaag gtcatattgc ggcttgccca ataaataaag acaaaaataa ctcccacaat
     9661 caacaaagtc atggctaaca tagtcagatt gaagataaca ggaccaatag agatgattgg
     9721 attaatactt tcttccatct aaaatcctcc cttttcttct cgttccatgt atttatttga
     9781 taataaatga gaagacaaga gttacaaaga aagttccttc aataaaggca acacctaaaa
     9841 acatcaaact acgaaactca gaaagcatat ctggttggcg tgctactgat ttaaacagtc
     9901 cattcatcaa taaaccttca ccgacagata cgcccataca ggcaatacat aagcctaaaa
     9961 atgttaaatt cataacaaat tctcctttaa aataaaattt acttacttag tgtagtccta
    10021 aaatttaaat ttgtcaactt ttaaccgcta ttggaagcgt ttaataaaaa ttatttccat
    10081 tttgctaaat ttcaagttca agttagccat ccagaagtct tctctgggtg acttgtagtc
    10141 caagcatttt ttaggatagt tgttaatcca cttttcgatg aatgcgactt ctttgggagt
    10201 cattttcttg gttcccttag gtaaccatct acgaatgagc ctgttgtgat tctcattagt
    10261 tcccctttcc caagaggcat agggatgtgc ataataaatg tgctcctcag aaaatacatt
    10321 agacaagcga ttgaattccg ttccattatc tgccgtgatg gaaagaatct tgtgttgttt
    10381 taagatgagt tttagagcct gattgaccac ctcagcactt ttatttggaa tcaatcggat
    10441 gatctgatgt ctactttttc gatccgtcaa gacaagcaag cagtagtttt tcgctctcgt
    10501 aagtagaacc gtatcaatct cataatgccc attctccaag cgaagattga tagcttcagg
    10561 ccgctgttcg atggattgac cagcaggttt aaagttggtg ctggcctgtt tcttaagcgc
    10621 ttttcctttt ctagggtaaa gcagatcctg cttgctttac cccaattttc catgatgaat
    10681 ccaatagtaa atggttgaaa ttcccacgtt aaccccttta gccataacca tcatttcagg
    10741 caaaaatttt tggttatgat agtggagaat cttttccttt agttccttgg tcacgcttga
    10801 tctcttgacc gagtgcttgc gattattttc ataagactgt tgagcatagt cggcagaata
    10861 aacctctttg aagcgccctt ttccaagaca ttttcggact gtcctacgct tgattttagt
    10921 gtggatagtt tgaggagctt ttccaagcag agaggcaatt tctctatttg atttcccttt
    10981 gttcgccttt tgtagtataa tggttttgca tctctgtgcc tttcttgtgt ttgtggttga
    11041 acaacaagta taacacagag gtgttttctt atgcctacaa gagctttcat tatttccatt
    11101 ttctttcgga tttcactcta ttctgaaaaa cttgtgtata tttactgaag ctagcaagtc
    11161 ttacctgtaa atttaatgaa agcaacacaa aatccgagag gggaatctcg gattaatgtc
    11221 aatttaaaaa gatagagagt ttttagttta aataaattgt tttaaaatat caacaacatc
    11281 acttcttttc ttaacctgat aagccttgat tcctaatttt ggagctacga ttatattgtc
    11341 ctcaatatcg tctagaaaga cacaatttct aggttataac tggtatttat cgatagttac
    11401 tcatatacat cagtccacct ccatacttat gtgcgagcct ctctttgtat tatacctcca
    11461 tactcacctt acagattctt ttggtaataa tatctttgcc taatgtagag atagtcttgc
    11521 aaagaaaaaa cttccttgta gccatgtttc tgataaaagt ccggtgcctg gaactgataa
    11581 gtattgacaa aggcaaaaca acaatttcga ttcttagctt cactttctgc ctgttgcaat
    11641 agttttgaac cgattccttg ccctcgcagt tcctctttta caaacaaata ctcgatttct
    11701 agccaatttc caaaagtctc tgctatcaaa cccgcaagga gattgccctt ttcatcttcg
    11761 acataaagat taagtggctc actttcagcc tcttcccttt ttgaacggtt ataaacacga
    11821 atcagattcc ctatttcttg cgatttatgt gattccttat tttccaatct aaagtataat
    11881 gaaatgaaat aaaacatgcg caaatcgatt aaggaattta atctaatttc taataatgtc
    11941 ttagaaatca aagtttacta ttttaacttc aatgcactat acatctaata ctcaatgaaa
    12001 atcaaagagc aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgga
    12061 gatagaactg acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa
    12121 gtcagctcaa aacactgttt tgaggttgta gatgaaactg acgaagtcag ctcaaaacat
    12181 ggttttgagg ttgtagatga aactgatgaa gtcagctcaa aacactgttt tgaggttgta
    12241 gatgaaactg acgaagttag ctcaaaacac tgttttgagg ttgtagatga aactgacgaa
    12301 gtcagctcaa aacatagttt tgaggttgta gatgaaactg acgaagttag ctcaaaacac
    12361 tgttttgagg ttgtagatga aactgacgaa gtcagctcaa aacatagttt tgaggttgta
    12421 gatgaaactg acgaagttag ctcaaaacac tgttttgagg ttgtaaatga aactgacaaa
    12481 gtcagtaacc atacatacgg caaggcgacg ctgacgtggt ttgaagagat tttcgaagaa
    12541 tagcaaaatg gaaaaaggag tgagtgaagc acatcgcctc cccactcctt tttctgtttt
    12601 taggctgttt tttcaacctt caagattttt acatcatagc taccaacagg cgtttcaatg
    12661 gttgctgtgt cacctgtttt cttgccaatc aaggcctgcc caattgggct ttcatttgaa
    12721 accttacctg caaaggcatc cgcaccagct gaacctacga taatataaac ttcttcttcg
    12781 tcctcaccaa tttcttggat ggtgactgtt ttaccaatcg ctacttcgtc ctgggcaact
    12841 gcgtcgctat tgacgatttc agcatagcgg atttttgttt ctaagctaga gatttgtcct
    12901 tcgacaaagg cttgttcatc cttagctgct tcgtactcac tgttttctga aagatcaccg
    12961 tatgaacggg caatcttaat gcgttctacc acttctggtc gacgaaccaa tttcaattct
    13021 tctaattctt tttcaagttt ctccttttcc tcaagggtca taggatatgt tttttctgcc
    13081 atttttctca actttcttct gataatattt tctaaagaaa attatgtgaa gtatcacata
    13141 attttagttt gtttagttta atttgctgtt gacatgttca gcgacattgc ggtcgtggtc
    13201 ttcttgattg ttagcatagt agaccttgcc ttctgtgaca tctgctacaa agtataggtt
    13261 atcgctctta gtttgattga tgcttgactc aatcgcatcc agacttggac tatcgactgg
    13321 accaggcatg agacctacat ttttataaac attataaggt gaatcaatgt tggtatcaat
    13381 cgcaacatcc tcagctagac tgatattttg ccccagtttt ccttgggcat acaagattgc
    13441 aatattactt tgaagtggca tatcacgatt caaacgattg tagaatacac ctgcaatgag
    13501 cttacgatct tctgtcttgg caccttcttt ttcgaccaag gaagcaatgg tcaacaactc
    13561 attgacagtc aagtttttag atttgatagt actatagtaa ggagataggt tcttatccat
    13621 agcagctaac atctcatcaa tcaagctctc aatagttgtg ctttccttga tagagtatgt
    13681 agctgggaaa aggtatcctt ccaaacgata acgcgcaccg ctgtctttta caggcaaact
    13741 ttccagtaaa gtaggatatt tcgctactgc ttgactgata aacgtctcat cttgaacttt
    13801 agccaagaaa gcctccgctg tcaaagactc tttgaagtca ccttgcaatt gacccacagt
    13861 ttgagcaatc tgatccaagg tataaccttc tggaattgtc aaagtcgcaa gtacaggttc
    13921 ttgcggttca tctgttccac ctttttgcaa ctctttgagt aagtcttctg tactcatact
    13981 cttttgcaaa ttgtagtaac ctgctttcaa gtcggtataa tttttatact tggcataaaa
    14041 actaaaaatc agaccatgct ttaccaaacc agctttttca agcgtcgtac cgatttcttg
    14101 aacgtttgaa ccttctggaa ttccaaccgt cacatatttc ttagaattag catcgatagg
    14161 taataaggaa tctagcacgt actggtaacc aaagtaacca cctgctgaga gcaaggcaag
    14221 gaatacaagg aatgaaatca caaaagcttt cacatgtgac ttcttctctt tcttaggctt
    14281 aacgggtttt gctccttctc tacggctacg acgtgatgta tctctgatga tatccactgt
    14341 ttctatagca ggcgtaggtg tttctggacc tgcttgttct gcttttttct ctgccgtcgt
    14401 ataggaaaca gctacccttg ttggggtttc attgtattct ctttcaagtt tcttaggtct
    14461 aacaggacct ggacctggtc ttgatccact ttcttccgct ggagaagaag gtacatcttg
    14521 acttggatga cttggaacac caggagtttc tctttgaatc tcatctgctg gagaagctgg
    14581 tacaccttga cttgggtgag taggcacggt aggagctttt ctcataatct cctctaccgt
    14641 tgacaaggaa tcagccatga gttcttcagc tgaaggttca tttgcaggag tgcgaactac
    14701 tgcctcatct tctttcagaa cttcatcata gccttttact ttttctaaat ctctcagaat
    14761 ctgctcttta aagcttaatt tctcttcttc tcttgacttt tcactcaaaa gtttttcctc
    14821 cttgttgata atccataata ttatatctta aaagtccaaa aaaagcaatc tatgatactt
    14881 ttcctaactt attttttcat ttcccagacc atatcatacc atgtttcccc tgcaaaggtt
    14941 gactgggact ggccttcgtt gacaaatcca tgtttttcat aataggcgat gagatagtca
    15001 tgacaggtta gattaatgcc atctctctca tcttcaagag caacttcttt caaggctgtc
    15061 agcaatttct gacccagtcc gagtccctgt gcctccttgg caatagacag acaggtcaca
    15121 gagatataac caccaggctc atgactatag tcttttattt cttctgtaaa agactggtct
    15181 tgcagatggc ggtgcaggcc aactggtcct tcgatataac ccatgattct tccttctttt
    15241 tcagcaacca gaaaagaggt ctgaatttct ctcaaatgtg cttcaaagac agaaggagga
    15301 atggcttctt cgaccgaaaa attttcaaat tcaagttcaa caatccgatc caaatcttct
    15361 aatcttgctt gtctgatttt cattgttcct ccagataaaa gggattaaac caaatcatac
    15421 tatagccctg gctagttgca tagagtaaag ttgcttcttc atcaacaaaa ccgttcattt
    15481 caaaatagga aagcagctca tcaggactct ccaaacgaat ccctttgtaa tccagctcaa
    15541 ctgccacctc tttcaaggct gcaagaagaa gtgttcccag gccctgtctc tgatggtcag
    15601 actcgatgac taaagaatgt acttttagac attgcggatt gtctgactgg ggacttgata
    15661 aaatatagcc taaaagttga ttttcatccc tagctagaag aaaggtatcc gcacacttac
    15721 ggatactttc ttctaaaata tgggaaagtt gctgcttttc agctggaaaa gacgaggtct
    15781 gaagtgcccc tatctcaggc aaatcagact tgcttgcctg aatgatctta attggaattt
    15841 ccatgggaac atcctattga acattgcttg tcaagttaga caagagacgc tcaaatgagt
    15901 attcataggt ttggatgtct cctgctccca taaagacgta aacagcattg tcatggtcta
    15961 ggagtggaga aacattttca acagtaatca cttggtgttt tttgttgatt ttgttggcta
    16021 ggtcttctac cttaacgtca ccatgatcta cttcacgagc cgagccataa atttgcgcta
    16081 gataaatagc atctgcttgg tttaaagcat gggcaaagtc gtccaacaag gcaatggttc
    16141 ttgtaaaggt atgcggttga aagactgcta caatttcctt gcttgggtat ttctgacgag
    16201 ccgcatccaa ggtcgcaata atttctgttg gatgatgggc aaagtcatcg ataatcactg
    16261 tatcattgac aattttctca gtgaaacgac gtttaacacc ggaaaatgtt ttcaagtgct
    16321 cacgcaccaa gttcaaatca aatcctgctg tgtaaagaag accaataacg gctgtcgcat
    16381 tcatgatatt gtgacgacca aaggttggaa tgtggaattg ccccaagttt tgtccacgga
    16441 aatgaacggt gaaggttgaa ccagttgttg aacgaagaag atcactagct acaaagtcat
    16501 tgccttcagc ttcaaaacca taataataaa ttggtgcatc agacgtaatc ttacgcaatt
    16561 cagcatcttc accatagaca aaaagaccct tggtgatttg tttggcatag tcgttaaagg
    16621 cattgaaaac atcctcgaga cttgtgaaat aatctggatg gtcaaagtca atgttggtga
    16681 taatagagta ttctgggtgg taaggcatga agtgacgctc atattcgtca gattcaaaga
    16741 caaaatattt ggcattggcc gaaccacgac ctgtcccatc tccaatcaag aagctggtat
    16801 ctgtaatgtg agacaagaca tgagacaaca tacctgtcgt tgaagttttt ccatgtgctc
    16861 ctgctactcc catgctaaca aagtcacgca taaagctacc tagaaactca tggtaacgtt
    16921 tgtagctgat accattttgg tccgcatagg caatttcgac gttgttatct ggacgaaagg
    16981 catttccagc gataatttcc atatcaccgt ctagattctt ttcatcaaaa ggaagaatgg
    17041 taattcctgc ctgctcaaga ccgcgttggg taaagtagta cttttcaaca tctgatccct
    17101 gaaccttgtg ccccatctgg tgcaacatca aggccaaggc actcatccct gatcccttaa
    17161 ttccgataaa atgatatgtc tttgacatgt tttctcccct attctgtcat tctggtcaga
    17221 ttcaactctt gggcaacccg acgttcttgt tctgtttgtt tacttttttt attgtagatt
    17281 tggctcttct ttagaaaatc ataattgttt ttctttggag caggtgctga cacttcttca
    17341 ttcttggtag ggatagaatg aacttcttcc gccaagatat aatgagactg ggtcaatttt
    17401 tggctatatt tgacaaattc accaggattt tccttttgga aaggagttgt cggttgattg
    17461 ccctgtctaa ctagactggg ctgagaatga cgtctcgcaa ggctgaaatc ctgagttaga
    17521 tagttagcag agcgtttctt tttcaagtct gcacgcgctt cttcacgcgc cacctccgca
    17581 tagctctttc cttctttttt aacccctaaa ggagcttttt taggtttccc tacttgcttt
    17641 tcaatcggtt ttactggttt ttcttcagca ataggagccc attctaaata atttttatct
    17701 cgatactcac ccttgatatt actgatcaga tcagactcat catagagatt catgactggc
    17761 atttcagtca acatgacctc gtcatctgac accaatggaa atcgttcttg tttcattttc
    17821 tatttccttt caacacttca ttatagcgta ttgtcttgat ttttcaagtg ctggcttcag
    17881 aaattcccaa aatttctcta atttctgcta gggtcagact accacgtgac tctgtgccgt
    17941 ccaatacttg tgacaccaga tgtttctttt gttcttggag ttcctgaatt ttttcttcaa
    18001 tggttccctt ggtcaccaag cgatagacct caaccgtttc ttcctgaccc atccgatggg
    18061 cacggccaat ggcttgcgct tccaccgcag gattccacca aaggtcaacc aagatcactg
    18121 tatctgcacc tgtcaggttc agaccgaccc caccagcctt gagggaaatc agaaaggcat
    18181 ctctttctcc ttgattaaag gccttggtca tgtcttgtct ttccttggct ggggttgaac
    18241 ccgtaatttt aaaggaagtc aggcccaagt ctggcagttc ttgttcaatt ttttccaaca
    18301 ttcccttgaa ctgagagaaa atcaagacac ggtgtccgcc gtctgccacc tgtaccagta
    18361 ggtctcggag actatctagt ttgccgctgg ctccctgata atcttccata aacagggcag
    18421 gagtgtcaca tatttgacgc aagcgcatca aaccagataa aatttccaca cgacttcgct
    18481 gaaattcctg ttctgacact tgagccagat ggtctcgcat ctgttgtaac tgggcaaggt
    18541 aaatagcctt ttgctggtct tccagttcat ttttataaac cacctcaatc aagtctggca
    18601 attcagtcag aacttcttct ttcttgcgtc gcatcacgaa aggcttgata aactgagcca
    18661 ctcgctctgc tggcaatttc ataaattctt tcttgcttgg caaaagtccg ggcatgacga
    18721 tttggaaaat agaccacaac tcacccagat ggttttcaat cggagttcct gacaaggcaa
    18781 agaccgacgg caccacaaat tgtctcaagg tctgggcaat cttggtctgg gcatttttca
    18841 tgacctgagc ttcatctaag aaaaggaagt caaaggccat cccctgataa agctcactgt
    18901 cctgacggaa ggtggcatag ctagtcacat agatttgatg gctctcggca agaatctcct
    18961 cacgacttgc tttcaaacca tgaacaacag ccacatccaa ctgtggagca aatttctgaa
    19021 actcatctgc ccagttgtaa atcaaacccg acggagcgag aatcaaaacc cgactttctt
    19081 ttgtcacttg actagtcaaa aaagcaatgg tctgaagggt tttcccaagt cccatatcat
    19141 cagccaaaat cccaccaaaa ccataatgat ggagcatctg caaccagcca attccctttt
    19201 cctgataatc tcgcaagtca gccttgacct gagttgcttg caaaggaaag tcctctggat
    19261 gcgtcaaatc ctgggccaga ttctggaatt cttgtgaaaa agaaacacgg tctcgccctt
    19321 caaagagatg agctaaactg taggccaagg atttccgagc ctgcaaggtc ccatctttta
    19381 attcaaattg ccccagttcc tgtagatttt ggcgaatttt cttggtttct tcatcgaaaa
    19441 agtaaacttg attagacgaa tcaatataaa aatcctgatt ggcaaccaag gcctgcatgg
    19501 cttggtcgat ttcctcctgg gcaatatctt gaaaatcaaa ctggatttcc aagagacctc
    19561 ccttggaagc aatctgcacc tgaggactcg ctaggctata aagctcttct agtttatctg
    19621 ataggtcaac atgcccgagt ttttcaaaga ctggaatgat atcatgaaaa aaatgataga
    19681 cagactccgc ttttaaggcc tgacgccaag attgaaaatc ggattcaaag cccgcagcca
    19741 aacagacttg gaaaattctt tcttctaagt ccgcgtcact tgaaaatggt aattcttcta
    19801 gctcttgtcg gctagatacc tgtctatttc cataatcaaa ctgaatttct aaacgaatcc
    19861 gattatcttc ttccctgtca aagtaaaaag agggcgcaaa agttttaatt tgtagacgtt
    19921 ctggagctga aacggtgccc atctggataa aaagagtcag acaggaggcc aatttgtctc
    19981 gatcactgct atcaaattgc aggtatttct ttccttgttg acccacaggt aacgctttaa
    20041 tttccttgag aagacgcatc tgctggtctg ttaaaaaata aacctgacct ttatggaaaa
    20101 gtactgctcc ttgataaaag acattgaccc taggactctc actgatttcc atttcaaaat
    20161 agtccgagta ttctgttact gtaaaggcaa atagattggc atcagcatgc atatcctgaa
    20221 aaagcagggt ttggtagcta tccacttgat ggtcaaattg aaaatggggc aaggccatca
    20281 gtaaattcac accctgctca aaaaaggtca gagggaaaaa gaggtgccga ccttggtttt
    20341 ggaaaaagag gtctggaacc agcccttcct ccgttagtcc gtgcaagaaa gtcaaaagtt
    20401 cttggctggc atcatcaaag gcttcccaag aaagagactc ctcataaatc ttgccaatca
    20461 tatacgactt tctctgctcg acaatcctta aaaaaagtag aatatcccga atgacatagt
    20521 atttttggct attgatttgg ccgattctca gagtccacaa gatatgattg gttcctgctt
    20581 ccacctgacc cacagctgat aactcatagg cgcattctga ttttggagat aaaattcgat
    20641 tcaaaaactt gccacccaag gtcaccttgg tttcaacggc ctctttttct tcatgacctt
    20701 cttccagact ccacaagatt tcctgaccac gctcatcatt tttcagaaaa tgctctagcg
    20761 ctgccaaatg cacacagtag cccctctttt gaaaagaatc acaggcacaa aaaaccaaat
    20821 catcctctaa actatagcgc agttcttctt ctgcaacgcg agcgtagagc cgattgttct
    20881 tttccttgat gatatcaacc ttaccagttt cataaagggc aacaccttcg atacgaattt
    20941 tccccggaat caatttagcc atattttcac ctttacctta tctttttatt ataccatatt
    21001 ttcgcctatg aaaatagcct tctaggaaga cttttctcct agaaggctgg atttttaacg
    21061 tttggcaaaa gtagccacaa tccgctgaca gacttcttgc aacagagatt tgggcatagc
    21121 tatattgatg cgggcatgga gacttccttc ctctccaaaa tccaaaccac ggttgaggat
    21181 aaccttggct tcatttctca acaactcttg caatgtttca tcagtcaggt cataagctga
    21241 aaagtcaagc caaatcaagt aggtaccttg cggtttcatg accttgattt tagtctcttt
    21301 tccaaataga tccatcacat aattgatgtg gtcttcaaag acttgcttga gttcctctag
    21361 ccaatcttta ccgtatcgat aggcagcttc tgtcgccaaa taacccaagc ctgaaatttc
    21421 atgctgatta ttggccaaca ggcgtttctg gaaagccagt ctcaacttag gattttcaat
    21481 gactgcatag gaattttttg ttccagcaat attaaatgtt ttagtggcac tgctcaagac
    21541 gatagcaaaa tttttgaagg caggattgat ggtattgaaa gactggtgtt tgtgaccaaa
    21601 gagggtcaaa tcttggtgaa tctcatccga aactaacaaa acaccgtgtt tttggcagag
    21661 ttggccaatc ttctccaaca cttctttttc ccaaacacgt ccaccaggat tgtgagggtt
    21721 gcaaagaaca tagagtttaa cctcctcttc caccaaatcc ttttcaagtt ggtcaaagtc
    21781 aatctcaaac agactatcct tttccactaa ggaattagta atcaatctac gattattcaa
    21841 cttgacactg cgagcaaagg gtgggtagac aggcgtgtta attaaaaccg cctcgccttc
    21901 ttttgtaaag gtttgaatag ctgttgagat ggctggtacc acaccctcga taaagacaag
    21961 agcctctttg tcaaagttgt aaccgtattg tgtagcttcc cacttttgaa cttccttaat
    22021 taagtcttca ctggcatagg tataaccata aaccagttgg tctgcgtaag tttgcacggc
    22081 ttggcggatt tcaggcaaga ccacaaagtc catatccgct atccaagctg gtagaacttc
    22141 actatccgtt tctgtttctt tccatttata ggtatggtgc cctaaacggt tgggcaggct
    22201 tgtaaaatca tattttccca tctttgtctt atccttctaa ggcttggcgc aaatctgcaa
    22261 tcaaatctct agtatcctca atcccaatag acaaacgcaa gaggtcatct gtcaaaccat
    22321 aagaatggcg tacttctgct ggaatatcag catgagtttg agtcgttgga taagtaataa
    22381 gactttccac tccgcccaaa ctttccgcaa aagagaagac cttgagactg ttcaaaatat
    22441 gaggaatgcg tgtttcatcg gctactttaa aggaaatcat gcctccacga ccagtgtaga
    22501 gaacttcctt aactgctgga gaatccttca aaaaggcaac cacttcttgg gcgttagctg
    22561 ttgagcgctc catacgaaga gacaaggtct tgagaccacg aagcaactgg tagctgtcaa
    22621 atggagacaa gactgcccct gttgtattga gattgtaaaa aagcttctcg tatagttcta
    22681 aactattggt cacaaccact ccagccaaga catcattatg gcctgctaga tacttggttg
    22741 ctgaatggag aacgatatct gctccatctt caatcggacg ttggtagata gggctataga
    22801 aggtattgtc caccaccact ttggcaccct tagcatgagc caattttgct agtttttcga
    22861 tatcaaattc caacatcaag ggattggttg gggtttcgat atagagaaca tccacatcct
    22921 tttctaactc ggcaatcaac tcttcttctg tattggcata ggtaaaatgg aaacgacctt
    22981 cctgctccac ttggttaaac cagcgaaaag aaccaccgta aagatcacgc actgccaaga
    23041 ccttacttcc tactggaaag acgctaaagg ccagtacaat agctgacatc cctgagctag
    23101 tcgctagggc atagtctgct gactcaatag ccgccaagac ttcctcagcc ttactacgag
    23161 ttggattttt agtgcgcgta tagtcaaacc cagtagatcg accaaactct ggatgctgat
    23221 aggtcgttga aaaatgaagt ggtgtcacca aagcacctgt tgcctcatca gacttgatcc
    23281 ctgcttgtgc taaaattgtg ttaatgtgta attccttgct catacaattc ctccaaatct
    23341 atagtaacta ttgtaccact tattttcatc aactcatttt cttcttttca agagctagtt
    23401 atagtttcaa actatataaa aagggagttt ttcctgctcc ctttaataga ctataaaatg
    23461 gtgaatctca aaagacacct tcactctatc atttgctcct gcacaaaacg agcataacgc
    23521 tcatgatttt ccagtagttc cttatgagtt cctgagccag tgattttccc ctcctctaag
    23581 aagaaaatac aatccacatc ttttaccgtt gacaaacgat gcgctataat cacaaccgtc
    23641 ttctccttta gtacagaata gaggctactg ataatcgcat actcagaatc cgcatcaaga
    23701 ttagcagtgg cttcatcaaa tataagaatt tcagcatctt ttaagtaggc tctagctatt
    23761 tgaagtcttt ggcttcgccc ccctgacaag agtcgtccgc gttcaccaac ttcagtatct
    23821 agtccctctt tcatggagcg aatctcatca cctagtgata ctaagtctag cactttcatc
    23881 aattcatcat cagttactaa gcgattcaaa ccgagacaaa gattgtcacg aatactgcca
    23941 gataagactg cattattttg tgaaacccaa gcgattttac ttctccattc ttttaagtta
    24001 aaatcatata tacttgattg ctccattaga atatatcctg aaagcggttt ataaaaccgc
    24061 tctaacaaac gcacaatcgt tgattttcct gatccagatg gtccaacaaa agcaattttt
    24121 tgccccttga aaattgaaca agtaatatcc tttaagacag gtcgattttc atcataacca
    24181 aaatagacat ggttaaaatt caacccttgt cctgataccg attttcctcc ctcaaatttt
    24241 tctttaggaa ctgcaagcaa gttctccagt gcaactgaag atcccttgct actagaataa
    24301 atagttacaa aattagctat attactaata ggattaagta attgaaagag gtaaatcaaa
    24361 aacgaaacca aggttcccac agatatatat cctgcgctga cccgataacc cccataggtt
    24421 agcatcacaa ctatagtcgc aaagataaat aagagagcaa acgaggtctc aaaagaagta
    24481 accctatctg atttcagtga attgttttgt accctttcaa tacaattatc caaaacatcc
    24541 tgtacacttt tctctgcttg gttagtctta attaattcat gttcttgaat cttttcagtc
    24601 aattgccctg ttaaatttcc tcctgtaaac gacgactata cttttcactg atattggaaa
    24661 ggggcaagat aataaacatc atacaaggaa gagtgatgaa taaaagtaga gaaagattcc
    24721 aatcaagact aaataagact acaatggaac caagtaccat aactaaactc agaataatat
    24781 ttgggaaagt cgtaattaaa aactcacgaa tgacactcgt gtcattgaca atggcagaag
    24841 tcaactcccc actttggctc ttatcaaaga aggatttctc tgcataaatc aacccctcta
    24901 tcactttttt cctgattttt gctatctttt tttcacccga ttgactaaac agatagtaac
    24961 caatagaaga aaacaaggct tgaccaataa aaatcaaaaa cgattgaaat actttggaac
    25021 ctatattttc aatagaactc ccatctatta aaccctttaa gataagggga agcaacaaag
    25081 caagtagact agacagaaca agtaagaaac tccccataat caccttagta tctactctta
    25141 ataattttaa tttcataaat actccttata atatttcaac ggataaagtc gggaataact
    25201 caatttgagg ataaaatcta ataaatcttc ctataacaaa acgcataaca tctaggattt
    25261 tatatacctg atattatgcg tttttaagca caaagacttc ttacacaaac ttatctacaa
    25321 ttagatttta tttgacatgt tttgccaatt cttcttgggc ttttttattg gattcttctt
    25381 tttctttcaa ccatttttct ctggcttttg catattcgtc tgttgtgaca atcttatctt
    25441 gtactttgag gtatttatat gattcaaccc cttttgtacc ggttaaacca taggcagcag
    25501 caaatggtac ggttcttctc aatgatggtg ttcccccacg cgaaacactt ggaagaacta
    25561 aagaactatc aatcaaccaa gcttgaatat cagcatattt ctcataacgt ttggctggat
    25621 cttgctcttt attagcttct tccaacattt gagtatagac atccagtcca actgccttag
    25681 ccttgtcatt ggcctcacca ggctctagtc caagattttg cagaaatcct ccactattag
    25741 tattaaaaat atcgagatag gttgacgggt cttgataatc aggtccccaa ccgccatgat
    25801 ataaatcata atctttctga gcagctgttt gagcaaagta gcctgaactg tcaaactcat
    25861 ctgatgttaa ttgctgaatg tcaatcacta cattatcaga acctaaaaca gattcaattg
    25921 attgtttgat agaactaact ccttgtatgc ctactttatc tgttacttcc acagtcttat
    25981 ccaagtggat tgggaattga acaccctttg cttcgagttc tttcttagct tccgcaaact
    26041 tagccttggc tttctcagga ttgtagtaag ggtcttgacc atccgcaaag ttgatacctt
    26101 gccattcctt accatagttg accatcttag aggctacaac ttcaccaaag tcttttccct
    26161 tgatactgac aaagtttgga ggaaccacta ggttacgcaa aatctttgtt gcaccttctt
    26221 tcccttcaga ctgagcccca taagatgttc tgtcaaaagc aaaattgata gcctgacgga
    26281 agtttttatt gagaactgct tcctgagtcg atttcttttc aatgtcactt gttttagaag
    26341 tataattgta agacttccta tctaggttaa aattaaagaa atatgaagtt gaattttgca
    26401 tactatagat gatattgttt ttgtattttt ctttaatccc ttcatagctg gagctgttag
    26461 gaaaaagacg agccgtagta taagcaccag ctgtaaaatt acgttccagt gattcttggt
    26521 cgctaccatc atagtaggtc aatttcacat cgtctacaaa gacattctta gcatcccagt
    26581 aattagggtt tttcttatat tcaatagcag attttgagac aagtgctttc atcaagaaag
    26641 gtccattgta caaaatacta gatggatccg ccttcccaaa atcatcccct tttgatttca
    26701 ggaaatctgc attaacagga aaaagtatcg ttgcaagtgt ttttgaattc cagtaaagtt
    26761 ctggtttaac caaagtatat tgaaccgttt ggtcatcaag tgccttgaca ccgacagttg
    26821 aaaagtcgct tgttttacca gtgatatagt catccaaacc agcaacagag tcctgcacta
    26881 gatacaaagc ttctgatttt ttatcagctg catattgcaa acctgtcaca aaatcctggg
    26941 cagttacagg cgcatattct tctccctcag aagtaaacca cttggcatcc ttacgaagtt
    27001 tgtaggtata ggtcaaaccg tcctgagaaa cagtccaatc ctctgctaat gatggaataa
    27061 tattcccata ttggtcattt tctaataacc cgtctaccaa atttgcaaca atatcggatg
    27121 ttgctgcgcg gttttctgct agatagttca aactagatgg atcacttgaa taaacatagt
    27181 tataggtttt tgatgcagtg ctagaatttc cacacgcgct caataaaact cctgtaccca
    27241 ggacaagacc tgccaaggtt agatatttgc tcttagactt tttcatttcc agaacctcct
    27301 gctttaaata tttgttttat tatacaacgt ttggtttgtt tagtcaatta tttttccaaa
    27361 aaatcgaaaa aaacctcatt tgctattttt gaaagataat tttagctatt ttgacgcta
//
LOCUS       DAVHSI010000027        26504 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.027, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000027 DAVHSI010000000
VERSION     DAVHSI010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.027"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            20..760
                     /locus_tag="VVR21_001345"
     CDS             20..760
                     /locus_tag="VVR21_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6055220.1"
                     /translation="MKINRKKEILNLLENSDVISYQELAQSLHVSTMTIRRDVSELEK
                     ENLVIKEHGGVRKVTFNTKTTDEKRLLYPEEKDYIAQLAANLIEPNSVIYLSAGTTIL
                     ALAKHLKNQHKHIITNSLFTFNWLNEHNFENILLTGGEFVSKTEEFHGEHAERLVKDF
                     LIDYAFLATNGLVDDHLTAFSSFGGRLQSIAMNQSRKVYLLADHSKFGLNDSYIYGKL
                     SQIDAIISDDKLDPETKKYYQQFTDIIN"
     gene            777..1769
                     /locus_tag="VVR21_001346"
     CDS             777..1769
                     /locus_tag="VVR21_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HEU6055221.1"
                     /translation="MILIVTLNPSIELLYFEKNFTLGAHNRFQNSTIMAAGKGINCAR
                     ALSYLGINATALTLVGGKSGEFFKQHLAQEKFHPLYIPIDGETRHSITIMHNDNIHTE
                     IVEAGPKVDQGLKSQIFDTLLQVIKEKNISIVSLNGSVHSDDRDFYNDLIQFLRENTD
                     STLKILADFSQTALQKIVNDAIHLPDFIKPNMEEFCQLTGLSVTTKQEILDYLMDKPS
                     PIPYTLVSCGEQGAIAQFNGKLYDVTAPSINLVNPTGSGDSTVAGAIYAFEQNLSDED
                     IIRYATASGTANAMENGVGVARKEIVEKLIPQVIIKEIHKSWSLGQNSSRPQKS"
     gene            complement(1798..2663)
                     /locus_tag="VVR21_001347"
                     /pseudo
     CDS             complement(1798..2663)
                     /locus_tag="VVR21_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2833..4353)
                     /locus_tag="VVR21_001348"
     CDS             complement(2833..4353)
                     /locus_tag="VVR21_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU6055222.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALMAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKPAEQVAKEFLQEQGLLKK"
     gene            complement(4346..5074)
                     /locus_tag="VVR21_001349"
     CDS             complement(4346..5074)
                     /locus_tag="VVR21_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055223.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(5089..5853)
                     /locus_tag="VVR21_001350"
     CDS             complement(5089..5853)
                     /locus_tag="VVR21_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU6055224.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPESQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(5857..6300)
                     /locus_tag="VVR21_001351"
     CDS             complement(5857..6300)
                     /locus_tag="VVR21_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6055225.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(6982..7278)
                     /locus_tag="VVR21_001352"
     CDS             complement(6982..7278)
                     /locus_tag="VVR21_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6055226.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(7300..8364)
                     /gene="pepA"
                     /locus_tag="VVR21_001353"
     CDS             complement(7300..8364)
                     /gene="pepA"
                     /locus_tag="VVR21_001353"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU6055227.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            8765..9466
                     /gene="galE"
                     /locus_tag="VVR21_001354"
     CDS             8765..9466
                     /gene="galE"
                     /locus_tag="VVR21_001354"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU6055228.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRATVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            9889..10848
                     /locus_tag="VVR21_001355"
     CDS             9889..10848
                     /locus_tag="VVR21_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055229.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTHKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            10838..11794
                     /locus_tag="VVR21_001356"
     CDS             10838..11794
                     /locus_tag="VVR21_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU6055230.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFVLLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFILANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            11791..12543
                     /locus_tag="VVR21_001357"
     CDS             11791..12543
                     /locus_tag="VVR21_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6055231.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            12639..13604
                     /locus_tag="VVR21_001358"
     CDS             12639..13604
                     /locus_tag="VVR21_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6055232.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(13829..14071)
                     /gene="yidD"
                     /locus_tag="VVR21_001359"
     CDS             complement(13829..14071)
                     /gene="yidD"
                     /locus_tag="VVR21_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU6055233.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(14071..14793)
                     /locus_tag="VVR21_001360"
     CDS             complement(14071..14793)
                     /locus_tag="VVR21_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU6055234.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(14780..15349)
                     /locus_tag="VVR21_001361"
     CDS             complement(14780..15349)
                     /locus_tag="VVR21_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU6055235.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(15368..16096)
                     /locus_tag="VVR21_001362"
     CDS             complement(15368..16096)
                     /locus_tag="VVR21_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU6055236.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(16096..16836)
                     /gene="xerD"
                     /locus_tag="VVR21_001363"
     CDS             complement(16096..16836)
                     /gene="xerD"
                     /locus_tag="VVR21_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU6055237.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(16827..17288)
                     /locus_tag="VVR21_001364"
     CDS             complement(16827..17288)
                     /locus_tag="VVR21_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU6055238.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(17285..17806)
                     /locus_tag="VVR21_001365"
     CDS             complement(17285..17806)
                     /locus_tag="VVR21_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU6055239.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(17782..18753)
                     /locus_tag="VVR21_001366"
     CDS             complement(17782..18753)
                     /locus_tag="VVR21_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU6055240.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(18750..19544)
                     /gene="racE"
                     /locus_tag="VVR21_001367"
     CDS             complement(18750..19544)
                     /gene="racE"
                     /locus_tag="VVR21_001367"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU6055241.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(19751..19999)
                     /locus_tag="VVR21_001368"
     CDS             complement(19751..19999)
                     /locus_tag="VVR21_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU6055242.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(20255..21880)
                     /gene="treC"
                     /locus_tag="VVR21_001369"
     CDS             complement(20255..21880)
                     /gene="treC"
                     /locus_tag="VVR21_001369"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU6055243.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQSTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(22058..24025)
                     /gene="treP"
                     /locus_tag="VVR21_001370"
     CDS             complement(22058..24025)
                     /gene="treP"
                     /locus_tag="VVR21_001370"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU6055244.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24210..24920
                     /gene="treR"
                     /locus_tag="VVR21_001371"
     CDS             24210..24920
                     /gene="treR"
                     /locus_tag="VVR21_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU6055245.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            25076..26411
                     /locus_tag="VVR21_001372"
                     /pseudo
     CDS             25076..26411
                     /locus_tag="VVR21_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         7780 a         6004 c         5062 g         7658 t
ORIGIN      
        1 gaggggagca acctttattt tgaaaattaa tagaaaaaaa gaaattttaa atttgcttga
       61 aaacagcgat gtcatctcct atcaggaact tgcgcaatca ttacacgtct caacaatgac
      121 cattcgaaga gatgtttcag aattagaaaa agaaaatcta gttatcaaag aacacggcgg
      181 tgttcgaaaa gtaacattca atacgaaaac aactgatgaa aagcgtctgc tttatcctga
      241 agaaaaagat tacatcgcgc aacttgctgc taatttaatt gagccaaata gtgtcatcta
      301 tcttagcgct ggaactacta ttttagcact tgctaaacat ctgaaaaatc aacataagca
      361 tattataacg aatagcttgt ttacttttaa ttggctaaat gaacacaact ttgaaaatat
      421 actcctaact ggcggagagt ttgtttcaaa aacggaagag ttccatggtg agcatgctga
      481 aagactagta aaagattttc taatcgacta tgcattctta gcaaccaatg gcctcgttga
      541 tgatcattta acagcttttt catcttttgg tggacgttta caatctattg ctatgaatca
      601 atctagaaaa gtttatttac tagctgatca ttctaaattt ggcctaaacg attcctatat
      661 ttatggaaaa cttagccaaa tagatgctat tatttcagat gacaaattag atccagaaac
      721 caagaaatat tatcagcagt ttaccgatat tattaactaa agaaaggtat ctgcccatga
      781 ttctcatcgt tacattaaat ccatctatcg aattactcta tttcgaaaaa aactttacac
      841 taggtgctca taatcgtttc caaaattcta caattatggc cgctggtaaa ggaatcaact
      901 gtgctcgtgc cctctcttat ttgggaataa atgccactgc actaacccta gtcggtggta
      961 aatctggcga gtttttcaaa caacatcttg cacaagaaaa gtttcacccc ttatatattc
     1021 ctattgacgg agagactcgt cactcaataa ccatcatgca taatgacaat attcatacgg
     1081 aaattgttga ggcgggccca aaagtggacc aaggtttaaa atcacaaatc tttgatacat
     1141 tgttacaggt tatcaaggaa aagaatatca gcatcgtctc tttaaatggc tctgtacatt
     1201 cagatgatag ggatttctat aatgatttga ttcaattctt acgtgaaaac actgattcta
     1261 cattaaaaat attagctgat ttttcacaaa ctgccctaca aaaaattgtt aacgatgcaa
     1321 tacaccttcc tgactttatc aaaccaaata tggaagaatt ttgccaatta acaggattat
     1381 ctgtcaccac taagcaagaa atattagact acttgatgga caagccttct cctatcccat
     1441 acactctagt gtcttgtgga gagcaaggag ccatcgccca gtttaacggt aagttatacg
     1501 acgtcactgc accatccatt aatttggtca atccaacagg gtcaggagac tctactgtag
     1561 caggagctat ctatgctttt gaacagaact tatcggacga ggatatcatt cgctatgcta
     1621 cagctagtgg aactgcaaat gctatggaaa atggtgtagg agtcgcaaga aaagaaattg
     1681 tggaaaaatt aatccctcaa gttattatta aagaaatcca taaatcatgg agcctgggac
     1741 aaaatagttc tcgaccacaa aaaagctaga gatttccaat tgtggaactc tagcttttta
     1801 attttgagtc gttctcttat tgtattttag gaggttattg gccataagta ccaatcccat
     1861 gtcaattctc acttgacgct tgcccctcag attacatctc ttgtgaccca aacaagcctt
     1921 tatctgccca aagacaggtt tcacatcaat cttgcgttga gcgaaaatct gtctaccttg
     1981 gggagataaa agcgcctgac attctttagc tttcaagttt tgatagcgtt cgttcatata
     2041 cagtcctttt tgaggggctg attcaggttc atcagcgtag taaaccttga tttcctgttg
     2101 aaagtctgtc tgtgttttct ggtgcttgat atggtgaaaa cgatagcacc agccatcagg
     2161 atgtatgtag ctatcctcct tgtcattata gtgccaattc gctcagtttt tagctgactc
     2221 tttataccct ctcttttgtt tcttatcaaa catggcatat ttaatcagaa ggggagtgat
     2281 ttcttcttga aaatagactt gtatctgttc ttgaagtttg gcggagaatt tctctgtcgt
     2341 tttcttccac acaaaactat acttgttggc attggcttca atcttagttc cgtcaataaa
     2401 caaacaatct aaggtcacta actcttccat ttttcaattt ttcgaccaga gaaaatccct
     2461 tgtgaatagg caaatagaag agtagataca agcattttag ggtgataaga cgggcgatca
     2521 aaggcatgat aggaggtgta gaagtgacgt tcctccaagg tattcaccac tttttcaata
     2581 gtaaagacga gatggtcttg tggtaagaag gaactgattt ctagtggtaa agttgtttga
     2641 tttgtgttat agtgaatatg catgggatag cctttttaaa tggtttatta agcaattcta
     2701 ttttaccaag actatcgtaa ccatgcaaaa aaagcaacgg caaatccgtt gctttttttg
     2761 gagataagag actattgtcc caggctcttt tgtctaggga agaaagtggc tacctctgac
     2821 attcctctcc ttttatttct tcaacaaacc ttgttcttgg agaaactcct tggctacttg
     2881 ttctgctggc ttgccttcaa caccgacttg gtagttgagc tggctcatct ggctttctgt
     2941 aatcttacca gccaatgtat taagaactct ttccaactct gggtgtttct tgagaagagc
     3001 ttctttcatg agtggagccc cttgataagg tgggaagagt tgcttgtcat cttccaagac
     3061 ctgtaaatca taacgctcca attccgcatc agtcgaatag gcatccgtga tttgaatatc
     3121 ccctgactga attgcctgat aacgaagagc tggctgcata gtcgccacat tgagattgag
     3181 accatacatt gattgcaagc ccttatttcc atcttcacgg tcgttaaact caagcgtaaa
     3241 gcctgccttc agctgccctt ccactttttt caaatccgaa atggtcttca agccatattc
     3301 ttgagcaatc tttttcggaa cagctacagc ataggtattt tgataagaca taggtttgag
     3361 ataggctaga tgatcctgct tggcaatgcc atcacgcgcc acttgataaa cctgctctgg
     3421 ctcatgactc accttgggtg atggttgaag caaactttca gtcaccgtac cggtaaattc
     3481 aggataaatg tcaatatcac cttttttcag agcttcataa aggaaacttg tcgtcccaaa
     3541 attcggttta acagtcgcag tcatgctggt attttcttca atcagcaatt tatacatatt
     3601 agccaaaatt tctggttctg ggcctatttt cccagcaata atcaagtttt ccttctcttt
     3661 ttgagccaaa agggctggac tataagacag acccagtaat aaagccatca aggcaaaacc
     3721 agagaaaatc gtccgcaatt tcgctttttc cattactttt agtaggaagt taaaggcaat
     3781 agctagcact gcagaagaaa gggccccaat caaaatcaaa ctggcattat tacggtcaat
     3841 tcccaacagg ataaaggaac ccagtccccc tgccccaatc aaggtcgcca aggtagccgt
     3901 accgataatc aagaccgctg ccgtccgaat tccagacatg ataacaggca tggcaagtgg
     3961 aatttcaaac ttcttgagac gctcccatct ggtcatccca aaggcaatcc cagcctcttg
     4021 aagactcgga tcaattccct tcagcccagt aatagtattt tgtaaaatcg gaaaaatcgc
     4081 ataaatcact agagctgtca aagccggcaa ggtcccaatt cccatcaaag ggataaagag
     4141 ccccaacaag gccagagacg ggatggtctg gaaaatacct gcaatctgca agacccagtc
     4201 ggccagcttc tcatgatagc gaagaaaaac agccaaggga atcgcaagca aaatagctag
     4261 taacaaggtc aaaagtgaca actgcaaatg ttgagatagg gctgtcaacc aatcactaaa
     4321 acgatcctga aaagttgcaa ttaaattagt catgaacact acctccaaac aagtctgcta
     4381 caaagtctgt tgcaggcgct tttaaaattg tctcgggatt cgctacctgg cgaatttctc
     4441 catcctgcaa gacagcaata cggtccgcca acttcaaggc ttcatccgta tcatgggtta
     4501 caaaaatcgt tgtcatccca aactctttat gcaattcttt tgtcagaacc tgcaactgtt
     4561 ttctcgaaat agcatccaag gccgaaaagg gttcatccat gaggaaaatc ttgggctgac
     4621 caatcatagc tcggacaata ccgacccgtt gctgttctcc accagataat tcactaggta
     4681 agcgatgccc atactcggct actggtaaac caaccttagc caaaagctct tctgttttct
     4741 tcgtaatttc ttccttgctc caccccttca tttcaggaat gagagcaata ttttccgcaa
     4801 ctgttagatt tggaaaaaga gcaatagcct gtaaaacata accagtagaa agacgaagtt
     4861 cacgctcatc atagtctttg atgcgcttcc catccatata aatatttcca tcagttggtt
     4921 ccaaaagacg gttaatcatc ttgagcatgg tcgtcttacc tgatccagaa ggccctacta
     4981 aaaccataaa ttccccatcc tcaatctgta agttgacatc tctcaagaca tccttttctg
     5041 tgtagcgcag tgctacattt ttgtattcaa tcattctttg tcctcaattt aaaacttccc
     5101 tcgattagtc aagtcttcta ccttaggcat gacttcctta ttatcccaat gctccacaat
     5161 tttcccgttc tctaaacgga agatatcgta ctgggcataa gcaacgccat caatctgagt
     5221 ctgaccatag ctaaccacat agtttccttg tcctaagagt tggaaaacaa agtcaaaagt
     5281 gacactatat tcagccacat agtttttata agcagcactt ccttgtccaa tctcatgatt
     5341 atgctgaatc aaatcgtctg ccacataatc actccactgc tctagctccc cattttggaa
     5401 aatttctgtc aagaaacggc gaaccagctt tttattttct gctttcttat ccaaatcctt
     5461 gatttcaaaa tctccaaaaa tttgatctag ttgatcattt tcaggtgttc gatagtagtc
     5521 aacgacatcc caatgctcaa caatacgacc attctcatcc gcacggaaag tatccgtcgt
     5581 cacccattga gcttctccac cattcagata ttgatgaaca tgaacaaaga ccagattgcc
     5641 atcctcaatg gtgcggacaa tcttaatctg actctctgga tgacgctcaa agaaatctgc
     5701 aaagaaggct gcaaatcctt ctttcccgtc aggaacacct gtcgaatgtt ggatataggt
     5761 atcccctaca gactgggctt gagcctcagc aactcgtccg tcttgaatgg catggatgta
     5821 taggttgtga gcatttttca cttgttgtga catattctaa acctcatttc ccttctcttt
     5881 caaattcgcc aaaattcttt cttgaaaacc ttcaaattgg tgaatttctt cctctgaaaa
     5941 tcctttgtaa aagatagtat ccaatttctg actgacacga tgccccactt ctttctggga
     6001 cttgcctaac tccgttaaaa ctaaatactt cttacgcttg tcttttccac acggactaac
     6061 aattacaagc ttttgttcct ctagcttttt tatcatagtc gttagcgtat tattcgcaag
     6121 cccagtcgca agcgcgatat ctgtcgcagt tgcgcagcca gtttcactat tccataaaac
     6181 cgctaaaatc ttgccctgtt cacccctata aagagcctca ggatcttgac tcagtaactt
     6241 ttgaaaaatc cgcccattca acaaacgaat atgatgggct agcaaatgac tatctttcat
     6301 aacacctcca atttatttcg atatcgaaat gaataaaaca attgtaacac tcatcgttct
     6361 aactgtcaac tatttcgatt tagaaataat ttttgataat tatccacacc accatactcc
     6421 ggctcaacta acttttaacg agagtttcta aactccttcg tcctccagtc tacaaaagcc
     6481 ttccattcgt actatcctat attttatgag ggaacacatt tttcctatca gaccatttat
     6541 tttaaagata gaagtaaatc ataattgctt ccatctgttc ttttatagta tattgaagtt
     6601 agactagggc actgtatctt ctaaaacatt gatagaaagc gatttgaatt tcccaatcaa
     6661 tttgttcgta tttataacat tttgaaactg gaataggacg ctatgactgc taaaatattt
     6721 ctataaattc atttgatttt cctaatcaat ttgttcatat cttatttcat cccgctataa
     6781 tttcaccttg ccctatcttt ttcgtagcac ccttcaaaca gcctatcccc taccgtttga
     6841 cgattcctca cttcgctcca cttccattac agaagtttct tcactactat agtctcggct
     6901 gacttctcat gattccttgt tactactatt tgaacgctca cgagataggt cttacaaaaa
     6961 atgctttgat ccacaatgga atcaaagcat tttaaagagt tcctcataca taagcgcaga
     7021 agtcgcagtt cctctgtact tggcttcttc tcttttgata aagcgagcca agttgagcaa
     7081 ctcaggtgct ggatgtttgg gatttaggag caattcacga ttgaccaggc ctgagagacg
     7141 aactgcctgc aattgctcat ttgtagtagg cagtttttta gtagtctcta ggagagcagc
     7201 aactaaatct tcactcaaat catgtcgagc atgattgtaa agatctttta taaggctttc
     7261 taggtttggt tctaccatcc ctaccacctc ccttatggtt taataatgtt taatcaaatc
     7321 aaccgttgaa cgatccaatt tcttcaccaa ggcttgtaag aaagcttgcg cttctaggaa
     7381 gtcatccatt gcatagaggg tttggtgaga atggatataa cgagcgcaga caccgatagt
     7441 tgttgatggg acaccaccat ttttcagatg agctgcacct gcatctgttc cgcctttacc
     7501 acagtagtat tggtacttga taccagcttc ttcagccgtt gtcaaaagga aatccttcat
     7561 ccctgggaga agcaagtgac ctggatcata gaaacgaatc aaggttccat ctccaatctt
     7621 gccttgacca ccgtagacat cacctgctgg tgagcaatca actgcgagga agacttctgg
     7681 gtcaaacttg gttgtagagg tatgagcgcc acgcagacca acttcttctt ggacgttaga
     7741 acccagatag agttcattgc cgagtttttg acctgataaa gcttcagcta gctcgcttac
     7801 catgaggaca ccgtagcggt tatcccaagc ttttgagatg atattttttt cattggctgt
     7861 caaaattgca gaactatctg gtacgatggt atcaccagga cggatgccaa aactttctgc
     7921 ctcagccttg tccgcaaaac caccatcaaa aacgatatcg gcaatggctg gcatggttgg
     7981 tccccccttt ccacgagtca aatgcggagg aacagaacct gaaatcacag gaatttcatg
     8041 accatcacga gtcaagagtt tgaaacgttg gctgctaacc accatggggt tccagccacc
     8101 gatttctacg acacggaagg taccatctgg cttgatttcg ctgaccataa aaccaacttc
     8161 gtccatatga gaagcgacca agacgcgcgg tgcatccaca gcttctgaat gtttgatacc
     8221 aaaaatacca cccaagccat ctgtcaccac ttcatccaca tgcggtgtca acttttcacg
     8281 aagataagca cggacaggcg cttcatgacc tgagactgca gcaagttctg ttacttcttt
     8341 aatttttgaa aataatgttg tcatttcagt tccttctttc tttcatccat tttaccactt
     8401 tttataggag aaggatagtg ggaaggtgga tttctaagtt agtatcttag tcctgctcta
     8461 tcttagaaaa ggatagtatt ctcttgcatg tagtgcaaaa tctagtaaac attccaaaat
     8521 taactcgaat atttatttcc aaacaaaaaa acaatacacc atcaaagttg tttggatttt
     8581 tcatgaaatt tacagaaaat agttgacttc cctttcttct ttctttaaat atatagttgg
     8641 ttgagtttgg aatagtacgc tgtagctgct aaaacatttc tagaaattaa tttgactttc
     8701 ctaatagagt tgttcatatc ttatttcaat ttactatagt acaaaactag aaaaggaaaa
     8761 aatcatgacc aaaacaattc ttgttacagg tgggactagc tacattggct cccataccgt
     8821 taaagctctt ttaaatgctg gctatcaggt gcatgtcctc gataatctct ccacaggaaa
     8881 tcgagcgact gtggatagtc gtgctagctt taaagaactg gatgtttatg atgctagcgc
     8941 cttaaaggct tacttagaag aaaatcagat tgatgctgtc ctccattgtg caggtgaaat
     9001 tgttgtgagc gaaagtattg aaaatccaag taaatacttc actgccaacg ttgctggtat
     9061 gaaccaagtt ctcaaagtct tatctgaagt tggcattcaa aaaatcatgt tctcttcgac
     9121 tgcttctctc tatggaaata actgtattga caagccggtg actgaagata ccctgctcga
     9181 ccctgtcaac ccttatgcag agacaaaact gatgggcgaa cgaatgattt actggatggc
     9241 caatcgctac gactggaaat atgttatttt ccgttacttt aatgctgctg gggctgaaat
     9301 ggatgcttca aacggtctgc gtgtgaaaaa tccaactcac atcattccaa atatcaacaa
     9361 gaccgcattg ggacaaaatg atagcttaaa aatatttgga gatgactacg atacacgtga
     9421 cggttcatgt attcgagatt acatttatgt cttggacctt gcataggctc atgttaaagg
     9481 aatgaactac ctatttcaag aagacagttc ttctcaaatc tttaacttag gaactaaaaa
     9541 aggctatact atcaaagaaa tctttaaaac tgctgaagaa ttactaaatt aaaaaatccc
     9601 acacgagatt gttgctcgac gtgctagtga cccagccagt gtcctagcag atgcttcaaa
     9661 agctaaacaa tatcttgatt ggacggctag ctactccctc gaagatatta ttttatcaga
     9721 ttaaggtaaa aacattttag aataggataa caaaggagaa agtcttgttg ctctctcctt
     9781 gttgtattta ttaaattgtc agaaatttta ttgacagatt agaaaaataa tgttacattt
     9841 atatccgcag atatctttcg ataccaaatc tacatgaaag gacggggtat gaaactttct
     9901 cattatttaa ttggcttact tctactccta gtctttctct ctattagcat tgggaccagt
     9961 gatttttcat ggggaaagct atttgatttc gaccagcaga cctggctcct ctttcaagag
    10021 tcccgtctcc caagaactat cagtattctc ctgactgcct ctagtatgag tatggcaggc
    10081 cttctcatgc agactattac ccaaaatcag tttgctgcac cgagtacagt tggaacgact
    10141 gaagccgcca aactgggaat ggtgctgagc ctttttgtct ttccatcggc tagtctgacc
    10201 cacaagatgc tcttcgcttt tgtttcatcc atcgtattca ccctcttctt cctagccttt
    10261 atgaccattt ttactgtaaa ggaaaggtgg atgttgcctc tgattgggat catctatagc
    10321 gggattatcg gctcagtcac agaagttatc gcctatcgtt tcaatctggt tcagagtatg
    10381 actgcctgga cccagggctc cttctccatg attcagaccc atcagtatga gtggctcttc
    10441 ttaggcctca tcatcctgat aaccgtttgg aaattatccc aaaccttcac catcatgaat
    10501 ctagggaaag aaaccagcga gagtttgggg atttcctact ccctacttga aaaactggcc
    10561 ctctttctgg tggcgctaac gacaagcgtc accatgatta ccgtgggtgg cctaccattt
    10621 ctcggagtta tcgttcccaa tcttgttcgc aagcgctatg gagataatct aagtcaaacc
    10681 aaactcatgg tcgcactggt tggtgccaat ctagttctgg cttgcgatat cctatcccga
    10741 gttctgatta ggccctatga gttgtctgtc agtctcttgc taggaatcat cggtagtctc
    10801 gtctttatcc tacttctctg gagaggggga cgaaaagatg cagactaaaa gcaaacatac
    10861 caagctcttc tggattctca ttattcttgc catcggagct tgtcttctct acttttggcc
    10921 catcactcac ttgtcagcct ttgcttggaa gttgcgttcc caaaagatca tcgtttatct
    10981 cttggtagcc atcgcgactg ggatttcgac cattagtttt caaaccctga cggaaaatcg
    11041 cttcctgacg cctagtattt tgggaattga atccttctac gtcctactac aaaccctact
    11101 actggttttt gaaagcaagt ttcttcaact tggcaaatcc cctatcttag aattcctagt
    11161 cttacttctt gtccagtccc tcttctttct cgccttacaa ggttacttga agacactgat
    11221 gaagcaagac ctggtcttcg tcctgctgat ctgtctagcg ctcagaagtc tctttcgaaa
    11281 tatcagcacc ttccttcaag tcctaatgga tccaaacgaa tacgataaac tgcaaaatag
    11341 tctttttgcc tcctttcaac atctcaacac ttccatccta gccatcggtt ctctgatcat
    11401 cctcgctttg acaatctttt tctttcgaaa agcagtcgtt ctagatgtct tgcacctgca
    11461 aagagaaacg gctcagatat tgggactcga tgttgaaaaa gaacagaaag agctcctctg
    11521 gggaatcgtg cttttgacct caacggccac tgccttggta ggacctatgg ccttcttcgg
    11581 ctttatactg gccaacctca cctacctgat tgtcaaagac tatcagcaca agttactctt
    11641 tatagtggcc attctggttg gatttattag cttaaccttg gggcaagcct tgattgaacg
    11701 agtctttgca ctggaaattc gtatcagtat gatcattgag agtgtgggtg gcttcttatt
    11761 ctttatctta ctatatagga ggtctcgtca gtgaaactgg aaaacattga caaatccatt
    11821 caaaaacagg atattttgca aggcatttcg cttgaagtca gtcctcaaaa actgacagcc
    11881 tttattggtc caaatggtgc tggaaaatcg actctcctct ccatcatgag caggctaacc
    11941 aagaaagatc agggagttct cagtatcaaa ggacgtgaaa tcgagagctg gaattcgcaa
    12001 gaactggccc aagaactaac catcctaaaa cagaaaatca attaccaagc caaattgact
    12061 gttgaagaac tggtcagttt tggacgtttt ccctacagcc gaggtcgact tagatcagaa
    12121 gactgggaaa aaatccgaga aactctgaac tatttagaac tgaccaactt aaaagaccgc
    12181 tacatcaata gcctgtcagg ggggcaactc cagcgcgtct ttatcgctat ggtactggcc
    12241 caggatacgg actttatctt gctggacgaa ccactcaaca atctcgatat caagcaaagc
    12301 gtcagcatga tgcagattct tcgacgactg gtggaggaac tcggcaagac cattatcatc
    12361 gtcctccacg atatcaacat ggccagtcag tatgcagatg aaattgtcgc cttcaaggac
    12421 ggccaggtct ttagcaaggg aagaaccgat caaatcatgc aggctgacct gctcagtcaa
    12481 ctttatgaga ttcccatcac gctagctgat atcaatgaca aaaagatctg tatctatagc
    12541 tagtaacata aaagctcaag ttagagaacc ttcagtctct tagtcaataa gattaagaga
    12601 ctccctaaat cgttatcaca ttttaaaaag gagaaattat gaaaacatcc cttaaacttt
    12661 atttcactgc cctagtggcc agcttcttgc tcctacttgg tgcatgtagt acaaactcaa
    12721 gcactagtca gacagagacc agtagctctg ctccaacaga ggtaaccatt aaaagttcac
    12781 tggacgaggt caaactttcc aaagttcctg aaaagattgt gacctttgac ctcggcgctg
    12841 cggatactat tcgcgcttta ggatttgaaa aaaatatcgt cggaatgcct acaaaaactg
    12901 ttccgactta tctaaaagac ctagtgggaa ctgtcaaaaa tgttggttct atgaaagaac
    12961 ctgatttaga agctatcgcc gcccttgagc ctgatttgat tatcgcttca ccacgtacac
    13021 aaaaattcgt agacaaattc aaagaaatcg ccccaaccgt tctcttccaa gcaagcaagg
    13081 acgactactg gacttctacc aaggctaata tcgaatcctt agcaagtgcc ttcggcgaaa
    13141 ctggtacaca gaaagccaag gaagaattgg ccaagctaga caagagtatc caagaagtcg
    13201 ctactaaaaa tgaaagctct gacaaaaaag cccttgcgat cctccttaat gaaggaaaaa
    13261 tggcagcctt tggtgccaaa tctcgtttct ctttcttgta ccaaaccttg aaattcaaac
    13321 caactgatac aaaatttgaa gactcacgcc acggacaaga agtcagcttt gaaagtgtca
    13381 aagaaatcaa ccctgacatc ctctttgtca tcaaccgtac ccttgccatc ggtggggaca
    13441 actctagcaa cgacggtgtc ctagaaaatg cccttatcgc tgaaacacct gctgctaaaa
    13501 atggtaagat tatccaacta acaccagacc tctggtatct aagcggaggc ggacttgaat
    13561 caacaaaact catgattgaa gacatacaaa aagctttgaa ataagccact tcaaactcaa
    13621 tttaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt tgctcaaaac
    13681 actgttttga ggttgcagat gaaagctgat gcggtttgaa gagattttcg aagagtataa
    13741 aattttgaca ttctaaaacg catcctatca agttcactca aacctgatag gatgcgtttt
    13801 tatcattttg aaatctattt accccacctc attccccttc ttgatttcgt ttaagggaaa
    13861 agtggtctgg aacggggtcc ttacctgttt tcgaccaggg atgacaacgt aaaatccgag
    13921 ccaagcccat caatactccc ttaaaaccat gtttttcaat agcctgaatc atgtagttgg
    13981 aacaagtcag atcaaagcga caagagggtg gaaagactgg tgagataaaa cgttggtaaa
    14041 agcgcacagg cgctattaaa attcgtttca ttatttctta gttacagcca tggtgtgtag
    14101 ttggctgatt tcttttttat taagacgacg agattctcct ggacggagtc ctgtcaagtc
    14161 taggtgtccg aaacgagtcc gagacaactt atctacttgg agaccaacag cttcaaacat
    14221 ctttttaact tgatggttac gcccttcatg gatggtcaac tgcaccacag agcgattttt
    14281 gactgggtcc actttgagaa tttcataaac agctggcttg gttttcttac catcaatctc
    14341 aagaccacgg gtcaaggggc gaagattgtc cttattggcc acacctttaa cacgcgcgac
    14401 ataaaccttg tcaatctcat tacgagggtg aatcatctcg tctgtaaagt ccccatcatt
    14461 ggtcaaaatc aagacacctg atgtatccca gtccaaacga cccacagggt aaatacgttc
    14521 tttgacattg ggcaagaggt cgacaaccgt cttgcgaccc ttatcatctg tcacactgga
    14581 aatcacacca cgtggtttgt taagcagata gtagaccttt tcttcgttgt agataggttg
    14641 accttcaact tcgaccttgt cgcctgactt gatagtggtt gccagttcac gcaccacttg
    14701 gccgttaacc gtcaccaagc cttgcttgat cagctcttct gcttttctcc tactggccac
    14761 acctgcgtga gcaatatact tattgattct catcttcttc tatcctttca ccaaataatt
    14821 ggctttcttg ggcttgaatc tcaagctcat caatcactgg taattcttct aaatggttta
    14881 tccccatgta atctaggaaa taatccgtag tcacatagag gttggggcgc cccaatactt
    14941 cctttttccc gtcttccttt atcaggtcaa aagcctgcaa ctttgccaag gctccactcg
    15001 agttaactcc acggatggca tcaatttcta tccgcgtaat cggctgtttg taggcaataa
    15061 tggacaaggt ctcaagggca gcccgagaca agctctggtt gataggcgcc ttagagtatt
    15121 ccttcaaaat ctctgcaaat tgaggcttgg tcaccaatct ataagcacca cttgtctcaa
    15181 tcaaagccaa actggaatct gggtcctttt catacttctg ggctaatttt cctaaacttt
    15241 gctggatgcc tgtcggtggc agagagagga gttcagctaa ctggcggacc cgaatcccat
    15301 cttcacccgc tacaaacaag agcgcttcta tttttgctaa agtactcatc tttcctctct
    15361 atcaagtcta gctttgaggc acttgacttt cttccttctt ttccatgaga tagatatctc
    15421 cgaaactctc ctcttgcacg aggatcagct cctgggtttt gattaactct agggttgcca
    15481 aaaagagggt gatgacctct tggacattct gggcttcctt gaacaaatcc tgcaagcgca
    15541 attgatctcg tccaatcaag gactctttca cgataatcat catgtcctca atcttatact
    15601 catcccgcaa gatcgtcgtg tgattttgtg caaactcctc ttttttcttg gctaggatat
    15661 ttgaaaaagc caaaaagagg tcaatggtcg tcttgtcatg cacaagctcc gcatcttcgt
    15721 aaatcaactc tgtcggcgct ttggaataat actgggctcg ttcttggtgc ttggcttcca
    15781 agtgctcacc caagagcttg aacttgcgat attcttcgat ttgagagagg aggtcctgct
    15841 ccaggtcatc ccccaagtct gtcacttctg ctaccttcgg aaggagttta cgactcttaa
    15901 tcagcatgag ctgactagcc atgaccatgt actcacccgt cacttccaga cgcatggcct
    15961 gcagggttga gacataggct agatactgtt cgatgacttc cgtaatgggc acatcgtaga
    16021 tatccatctg gtacttagaa accagatgca agagcaagtc caggggtcct tcaaaatctt
    16081 ttaatttaat atccattatc tatatttttc taaggtcagg actgttttta atcctaattt
    16141 ttttgcaatt tcgtacaaat cgaccttgtt ttctatttgt cttagaataa actgttcacg
    16201 taagacttga gctgataagg atggaaaacc tttctccttg acaaaagatt ctaactgacg
    16261 aaaggcccac tgacgagaat agggtttctc tcctctttca aaaagatagg tctgccccat
    16321 caagggttcc aattctgaaa gcaaggccgt gggaatggtg acaatcctct gttgggaagc
    16381 cttgctgatt cgcaacacct gaaaatccag attgatgtcc gcaaccttga tggctaaaat
    16441 ctcactgggc aagagcccca tttctaggat taagagcgct agcaagcggc cctctggatg
    16501 gtcgctttcc tgccaaaaag agtctaggta tagaatctct ggcttttccg tcttcttttc
    16561 agcttgtttg gctaattcca agcggtaaaa gctgtccacc tctccttttt gatagagaaa
    16621 gtagagaaat tggttacagg ccgaaatctt tcgcttctgg gcgctgattt ttagattggc
    16681 tagctgggct tggtaaatct tgagactggt ctcagaaatc cgctcaccta ccatgtctaa
    16741 aaattgctcc aaatcatact tataggactg cttggaattg acagacaagc cctgcttttc
    16801 ctctaaaaag gctgaaatcc tgtctctcat tggcatcgaa tctcatattc cttactaaaa
    16861 tcatgcaaga gggcattaac ggccttgagg atggacttgc gcgtaataat cccttggaaa
    16921 ataccctctg tatccacaac cggtaagaag gactcatcta ctagcttgtg caagacctcc
    16981 gtaatggtga aatcaggcga aacaaccgct acgtccgttt ttgtcatatg aacgatatcc
    17041 gtatccgcca tgatttcttg gctcaagtca tgctccatct gataagccat aatatctctg
    17101 agtccaatcg tcccaacaaa ctgtttttca tctgtcacaa cgggaacacg ggtataggtc
    17161 atctgactaa gcaagagggt cgcatgatcc gcattgtggg tatcaatcaa cacagctaga
    17221 tttttagcag gggtcaaaaa agtttcctcc tgccccaaca agaaagtctc aaactccttg
    17281 gcaatcatcg gctaaactcc ttggacaaac ctggatacac ctcgtgatct cgtgtcaaaa
    17341 agtccacttt gaagtaacta tcatcaatct ccacacgagc atagagacat tctctgatgg
    17401 tacctcgtgg ttggctgata gaacctggat ttagaaagag gatcttgcct tccatccaag
    17461 cacttggcac atgcaagtga ccatagaggc agatagcggc ctcttcctcc tgagcccagt
    17521 agtccaactt ttgaaagttg aaattgatgt caaacaagtg accatgagtt tggataatct
    17581 tggtcgaacc aagctcagtc accagacgtt ctgggtagcc ggcgtagaag tccatgttcc
    17641 ctttaacaac gcggatgccc tcccaaagtg gagaatccgg acgtagttca gaatcgccgt
    17701 tatgaaaaac ggcatcgact ttgcccacat agcgatcacg gacttcttcc acaatcaagc
    17761 tatcgccatg ggaatcgctc attacaatga tggtttgctt tgccatgatg gaaatacctc
    17821 caaaagtttc ttaacggcta aggcacggtg agattgacta tttttttctt ccagggttaa
    17881 ttcagctgat gactcacctg tttctcctac aaggaagagg ggatcatagc caaagccatt
    17941 ttcaccctta ggttcaaagt taatataacc tgaccagtct gcttcaacaa ctaaactttc
    18001 cttatttggg ctggctacga ctagggttgt gtggaactga gccgagcggt ccttgagttc
    18061 aaagaccatg gccaattcgt gcaagagttt ggcattattt tcacggtcag ttgctcccac
    18121 acctgcgaaa cgagctgacc agacgcctgg taagccacca aggacatcga ctttgagacc
    18181 agaatcatct gccaaaacca tcttgcccgt taattgagaa atggtttctg ccttaaggcg
    18241 ggcattttct tcaaaggtca tacctgtttc tgctacttca ggcaggtcag ggtagtcatt
    18301 aagattttcc acatcgtagc ctaacttatc aaagatagct cggaattcct tggttttgcc
    18361 ttcgttacga gtcgcaatca acaaggtttc tctgaccttg cttgtctcaa agaaatcatg
    18421 aacattgacc ccttctttag gcaattctac atacaagagt tgcccatttt caaccaagag
    18481 cagggcccca tgacgttgaa taacttccaa gtttcgtccc atttcttgat taagcatatc
    18541 taccacaaag gagaacaaac ggtaggtaga accatagcgt aaaacagtaa ctgaaagcgg
    18601 gaaaccatac tcttcatctc caaatatttt ggagaattca aacagaggaa aatctgtctg
    18661 atagtcgctc aaactgttaa cgccaccaaa aatactataa gacccaacat accagtcctg
    18721 gtcatcctta tattcataaa ttttatttgt cataattcta catgctccac atgaatctct
    18781 ttttccagcc attcttcacc aatttgtgca aaactttggc tactggctgt tgtgtaaaaa
    18841 cggtgatgga gtggtccagc atcgcgacca cgattgattt caaaataatt gagtaagact
    18901 gagatatccc gtacgcactc tgccccacta tcgatgagct gaacctttgg ccccatcaca
    18961 ttttggataa tagggcgaag gagtggataa tgagtacagc ccaaaatcag gctatccacc
    19021 tttccaacca agggacgcag ggtttcatag accaccttct tggtaacact ggttgacagg
    19081 gcacctgact caaccaaggg agcaaacttg ggacaggcca agctctccac ctgtaagtcg
    19141 ggatccagat catggatttt ctgacggtat atgtctgatt gtaccgtcat gggcgttcca
    19201 atcactccga ttttcccacc ttgactggac ttgatggctg ccgaagctcc tggcaaaatt
    19261 acacccaaga caggaatatc tagttgagcc ttgatttctt cccagacgac cgcagtcgca
    19321 gtgttacaag caatgacaat cattttgaca tccttagtca agagaaagtt gaccagctgc
    19381 caagtatatt cacgaatttg ctcagcagga cgggggccat agggcgcccg cgccgaatct
    19441 ccaatataga cgatttcttc atggggaagc tggcgcatga gctcgcgcac aacggtcaag
    19501 cccccgacac ccgaatccaa aaaaccaatt ggtcgattat ccatacagtc ttctttctag
    19561 tcttttttct gattgatcgt tcattatgat tccttgtact gaacgaactg accgacagct
    19621 tgatagaatg tcaactacct ctctcttaat cataatcaaa tatcaataga atgcaaggaa
    19681 aaagtctcat ccctaaacca taaccaacat agtgagaagt ctggaacttt catcccagac
    19741 ttttccttat ttattttttc tttttattgt tagcaagggc tgccttttgt tggcggatga
    19801 tttggtggta aacttgttgt accttagctt cgcttggttt ttgaccattt gcactcaaaa
    19861 gagtacgaac tgcttcagca ttcaaacgtg ggttgtcagc aaattctttt tcgatttgct
    19921 tacgaaccaa gtacattcct ccaagagctc ctcctagaaa agctagcaca atcaatacaa
    19981 ttgctaaaag taaatccatc atttttctcc tgtttctttt tgagtccctt tcattatacc
    20041 acaaactagc caccctgacc agtttgttct acactttcaa ggatggaata gacagcaaaa
    20101 agaacgctgc ttttctgaaa aagaggtctc cttgctaagt ttatactcaa tgaaaatcaa
    20161 agagcaaact aggaagctag ccacaggttg ctcaaagcac cgctttgagg ttgcagataa
    20221 aactgacgtg gtttgaagag attttcgaag agtattaatt tacataaata gccagtgttt
    20281 gatagggttt gagtagaatt ttctcagaca cttctgcatc ttcatagttt gatatcaaaa
    20341 tctgtccatt ttggtagact gctggcaagt cgatttccac ttctttagca taaaagttat
    20401 tgagcactag taacttttga tcctcaaact ggcgttcaaa agcgtagact tgtttgctat
    20461 cttcaaaggc tggtttgtaa cttccttctg aaatgattgg catttcctta cgcagtcgaa
    20521 tcaagtcttg atagaaggta aaaatcggac cctggatttc attttctaca ttgatgtatt
    20581 tataggattt accagctttc aaccaaggag tgcctgttga aaatcctgca ttttccgaag
    20641 catcccactg catgggaatg cgtgaattat cacgcgactt agcttgaata atctggaagg
    20701 cttcttgctg actctttcct tcttctaaga gcatctgata ggcattaagc gattcgacat
    20761 ccacataatc agccatagaa tcatagtctg ggtcaatcat cccgatttcc tcacccatgt
    20821 agatataagg tgtcccacgt gacaggtgaa tgctggctgc tagcatggtg gctccttcct
    20881 tgcggaagtt ttgaatatcg acaaaacggt tcaaggcacg tggttgatcg tgattgttcc
    20941 aaaagagggc actccaaccg tctttatcac tcatttcctt accccaacta tggtaaagac
    21001 tcttcaactc ttcaaaatca aagggagcca aggtccactt ttgtccatcc ttatagtcca
    21061 ccttgaggtg atgaaaatta aaggtcatgg ataattcctg acgatcaggc gacgaataaa
    21121 ggacacagtt ttccatggtg gtagaagaca tttccccaac tgtcataaag ctatcgtcag
    21181 atccaaaagt ggcttggttc atcatacgca aatagttatg aacgatgggt ttgtctgtat
    21241 aagctggctt cccttcattt tcaggacagt ccactgaaac ctcgtcctta ccgatcaaat
    21301 tgatcacatc aaatcgaaaa cctttgacac ccttgtcgcg ccagaaatta acaaccttga
    21361 aaagctcctt acggacattg ggattgcgcc agttaaggtc agcctgggtc tcatcaaata
    21421 ggtgaagata gtatttccca gtatccccga aaggcgccca tgcagaacca ccaaacttag
    21481 actgccaatc tgttgattgg tcttggatga agaaaaagtc ttgataatac ttatcaccag
    21541 ctagggcttt ctgaaaccat tcatgctctg tcgaacaatg attaagtacc atgtccagca
    21601 taaagtcaat cttgtgctct ttaccgacac acaccatttc ctcaaaatca gccatatcac
    21661 caaaaagagg atccactgcc atataatctg aaatatcgta accattatcc cgttgagggc
    21721 ttggatagaa tggattgagc cagaccatat ccacacctag tttggctaaa tagggaattt
    21781 tttcgataat cccacggaaa tccccaatac cgttttcagt ggtgtctttg taagattttg
    21841 gatagatttg atagactact tttcctttat caagtgtcat ctgtttctcc ttttctgata
    21901 aaagggagga agcagtcttc cgtccctatt tgtgctattt caattatact caatgaaaat
    21961 caaagaacaa actaggaagc tagccacagg ttgctcaaaa cactattttg aggttgcaga
    22021 tagagctgac gtggtttgaa gagattttcg aagagtatta gattcgtgta gcgaccatga
    22081 gagatgctcc agcttggatc gttgtcggat aagttccggg aatagtcgct gtataagcat
    22141 cttggttggt gatgataaca ggagtttctg tcaccagacc tgcagcctta atgacatcca
    22201 tatcaaaacg aatcagttgc tgaccaactg taacgtgatc tccttggact acaagacttt
    22261 caaaaccttt gccatcaaga cctactgtat ccataccgat gtggatgagc aattcaactc
    22321 cctcgtcaga gacaatgccg atggcatgct tggtagggaa aagaaccgtc actgtcccat
    22381 taactggaga ggtcaactca ccttggcttg gttcaatgac tagaccttgc cccatgacac
    22441 ctgatgcaaa aataggatcc gtcgcttgac tcaattcttt cacttggcca gttagtgggc
    22501 tgataatttc taccgaagta agttctactg gttcatggtt cacaaattct gcttcttctt
    22561 gagcaacgaa ttctgcctgc aagttcgtat cgccctctgt ttttgtaaag agaccagcct
    22621 tgcggaagaa gaaagtcaag agcattggaa caacaatcgc aactagcata gttcctgcaa
    22681 atggcagcat gtattgaggt tgaatagaga gaatacctgg caaaccaccg ataccaatag
    22741 aagccgcagt tacattaaaa gtaacggata acatgcctgc aagggctgaa ccagtcatcc
    22801 cagcaacaaa tggataaata tattttacgt taaccccaaa aagagctggt tctgtaacac
    22861 cgagataggc tgaaatggtt gcaggaagtg aaacctgagc ctcacgctca tcatggcgat
    22921 gcatgaaata ataggcaaac acggctgagc cttgagcaat attagaaaga gcaatcattg
    22981 gccatagggc agtgccacca gcatccgcaa tcaattgtgt atcaatggca ttggtcatat
    23041 ggtgcagacc tgtgatgaca aatggagcgt agagggcacc aaaaattgca ccgaagagcc
    23101 atttaactgg accagttaaa cctgccaaga caactgatga aagtccttgt ccaattgtcc
    23161 aaccgattgg tcccaaaaca gtatgagcca aaatcaaggc tggaatcaat gacaaaaaag
    23221 gtacaaaaat catggaaatg acttctggga tatgtttgcg ccagaaaatt tcaagataag
    23281 acagactcaa acctgcaagc aaggctggga taacttgggc ttggtaacca atacgattaa
    23341 cagtaaaata accaaaattc caaacccagt ttgccgcgat atcagctgct ggcgttgaag
    23401 caaccgcata ggcattgagc aactgaggcg ataccaaaca gattccgaga acaattccca
    23461 aaatttggct ggttcccatc ttacgagaaa cagaccaagt aatccctact ggtaagaact
    23521 ggaagatagc ttcaccaggc aaccagagga agtgattgac tcctgcccaa aactgagagg
    23581 attctgtgat ggtcttgcca tccaacatcg accaatggac accttccaag acattacgga
    23641 aaccgaggat caatcctccg actatcaagg ctggaataat cggagtaaaa atctccgcca
    23701 gagtggtcat aacacgttgg accacgtttt gattactctt agctgcagac ttggctgctt
    23761 ctttggaaac accctcaata cctgaaacgg ctgtaaaatc attataaaag atgggcacgt
    23821 catttccaat gattacctga aattgacctg catttgtaaa agttccttta acagctggaa
    23881 ttgactcgat agctttaaca ttagccttct tatcatctcc taaaacaaag cgcatccgtg
    23941 tcgcacagtg agttacggca gtcacatttt ctttgcctcc aattgcctga agcagatctt
    24001 tggcttcttg ttcaaatttt cccatttgat tctccttata cttgtcaaag caagtttgat
    24061 ttgataagta tattgtaaac gataccaaac ttgtctgcaa cttgtttggt ataaaaaggg
    24121 tgtttttttg taaattttct agcacttgta tggtaaaata gatacaggtg ttcattaaac
    24181 tagactaaaa acctatttaa gcaggcaaaa tgaagaaata ccaacaatta tttaagcaaa
    24241 tccaagaaac cattcaaaac gagacttacg ctgtcggaga tttccttcct agcgagcacg
    24301 accttatgga gcaatatcaa gtgagtcgtg ataccgtccg aaaggccctg tctctcctcc
    24361 aagaggaagg attgatcaaa aagataagag ggcaaggttc tcaagtcgtc aaagaagaaa
    24421 ccgtcaattt ccctgtatcc aacctaacca gctaccaaga actagttaaa gaacttggac
    24481 tgcgctctaa aaccaacgtg gtcagtctgg acaagattat tattgataaa aaatcctcac
    24541 tgataaccgg tttcccagag tttcggatgg tttggaaggt ggtccgccag cgtgtggtgg
    24601 atgatctggt atccgttctg gatacggact atctggatat ggaactaatt ccaaatctca
    24661 ctcgccaaat tgctgagcag tctatctatt cttatataga aaatggcctc aaactcctta
    24721 ttgattatgc tcagaaggaa atcaccattg accactcaag cgaccgagac aagattctca
    24781 tggacattgg caaagaccct tatgtcgttt cgattaaatc aaaagtctat ctccaagacg
    24841 gacgccaatt tcagtttacc gaaagtcgcc ataagttaga aaaatttaga tttgtagatt
    24901 ttgcaaaacg caagaaataa aagactgaga caccagatct cagccttttt cggctctata
    24961 atatttgtag tgggtaaatc ccttatagat attatggagc ctatttttgt gtagaaaaaa
    25021 agtcccatat gacctataat gaaaagcgac aaaacaactc attagaaaga ttcatatgga
    25081 acaattacat tttatcacaa aactgctcga tattaaagac ccaaacatca agattctaga
    25141 tatcatcaat atggataccc acaaagaaat tatcgctaag ctggattatg aggctccatc
    25201 ttgccctgat tgtggaagtc taatgaagaa atatgacttt caaaaaccgt ctaagatccc
    25261 ttacctcgaa acaactggta tgccttctag aattctcctt agaaaacgcc gtttcaagtg
    25321 ctatcattgt tctaaaatga tggttgctga aacttctatc gtcaagaaga atcatcaaat
    25381 ccctcgtatc atcaaccaaa agattgctca aaagttaatt gaaaagattt ctatgaccga
    25441 tattgcccat cagctttcca tctcaacttc aactgtcatt cgaaagctca atgacttcca
    25501 ctttgagtgt aattttagaa atctgcctaa gattatgtct tgggacgttg aaacagtccg
    25561 gggagtgact gtttcaatcg ggagatggag atgagcttta ttgcgcaaga ttttgaaaag
    25621 ctcgatatca tcactgttct tgaaggtaga acacaagctg tcatccgaga tcactttctt
    25681 aaatatgata gagccgtccg atgtcgcgtc aaaatcatta ctatggatat gtttagccct
    25741 tactatgact tggctaaaca gcttcgcttt caaatttcta ggctcaggct gaaacagtct
    25801 cctagactgt ttcactcccg aatgctaaaa tcgttcttga tcgctttcac attgtacaac
    25861 atcttagccg tgctatgagt cgtgtgcgtg tccaaatcat gaatcagttt catcgaaaat
    25921 cccatgaaca caaggctatc aagcactact ggaagctcat acaacaggat agccgtaaac
    25981 tgagtgataa gcgattttat cgtcctactt ttcgtatgca cttaaccaat aaagagattt
    26041 taaacaagct tttgagttat tcggaagact tgaaacacca ctatcagctc tatcagctct
    26101 tgctttttca cttccagaat aaggaaccag agaaattttt cgaacttatc gaggacaatc
    26161 ttaagcaggt tcatcctatt tttcagactg tctttaaaac cttcctcaaa gataaagaaa
    26221 agattatcaa cgcccttcaa ctacactatt ctaatgccaa actggaagcg accaataatc
    26281 tcatcaaact tatcaagcgc aatgcctttg gttttcgaaa ctttgaaaac ttcaaaaaac
    26341 ggatttttat cgctttgaac atcaaaaaag aaaggacgaa atttgggctc tataatattt
    26401 gtagtgggta aatcccctat ggatattatg gagcttattt ttgtgtagaa aaaaagtccc
    26461 atatgaccta taatgaaaag cgacaaaaca actcattaga aaga
//
LOCUS       DAVHSI010000028        25908 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.028, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000028 DAVHSI010000000
VERSION     DAVHSI010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.028"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..267
                     /locus_tag="VVR21_001373"
     CDS             <1..267
                     /locus_tag="VVR21_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU6055246.1"
                     /translation="NFLPIIEENISKLLNSQKDEWKQLSYHREYVVKMAKALYLQATG
                     KTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYAGFHL"
     gene            435..779
                     /locus_tag="VVR21_001374"
     CDS             435..779
                     /locus_tag="VVR21_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6055247.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            789..2201
                     /gene="lacG"
                     /locus_tag="VVR21_001375"
     CDS             789..2201
                     /gene="lacG"
                     /locus_tag="VVR21_001375"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6055248.1"
                     /translation="MENLQFKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            2271..3950
                     /locus_tag="VVR21_001376"
     CDS             2271..3950
                     /locus_tag="VVR21_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6055249.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(4076..5515)
                     /locus_tag="VVR21_001377"
     CDS             complement(4076..5515)
                     /locus_tag="VVR21_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU6055250.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(5519..6868)
                     /gene="trkA"
                     /locus_tag="VVR21_001378"
     CDS             complement(5519..6868)
                     /gene="trkA"
                     /locus_tag="VVR21_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU6055251.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            7057..7905
                     /locus_tag="VVR21_001379"
     CDS             7057..7905
                     /locus_tag="VVR21_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU6055252.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            7920..8468
                     /locus_tag="VVR21_001380"
     CDS             7920..8468
                     /locus_tag="VVR21_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU6055253.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            8475..8732
                     /locus_tag="VVR21_001381"
     CDS             8475..8732
                     /locus_tag="VVR21_001381"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055254.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            8834..10516
                     /locus_tag="VVR21_001382"
     CDS             8834..10516
                     /locus_tag="VVR21_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055255.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            10501..10665
                     /locus_tag="VVR21_001383"
                     /pseudo
     CDS             10501..10665
                     /locus_tag="VVR21_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
     gene            10666..10860
                     /locus_tag="VVR21_001384"
                     /pseudo
     CDS             10666..10860
                     /locus_tag="VVR21_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
     gene            10865..11314
                     /locus_tag="VVR21_001385"
     CDS             10865..11314
                     /locus_tag="VVR21_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055256.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDWHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            11442..12029
                     /locus_tag="VVR21_001386"
     CDS             11442..12029
                     /locus_tag="VVR21_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU6055257.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            12419..14026
                     /locus_tag="VVR21_001387"
     CDS             12419..14026
                     /locus_tag="VVR21_001387"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU6055258.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(14585..16216)
                     /locus_tag="VVR21_001388"
     CDS             complement(14585..16216)
                     /locus_tag="VVR21_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU6055259.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSSAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTAYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            16509..21449
                     /locus_tag="VVR21_001389"
     CDS             16509..21449
                     /locus_tag="VVR21_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU6055260.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQIPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGH
                     EVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAIVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            21539..22735
                     /locus_tag="VVR21_001390"
     CDS             21539..22735
                     /locus_tag="VVR21_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU6055261.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQTG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            22871..23398
                     /locus_tag="VVR21_001391"
     CDS             22871..23398
                     /locus_tag="VVR21_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6055262.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            23475..23831
                     /gene="glnR"
                     /locus_tag="VVR21_001392"
     CDS             23475..23831
                     /gene="glnR"
                     /locus_tag="VVR21_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU6055263.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            23868..25214
                     /gene="glnA"
                     /locus_tag="VVR21_001393"
     CDS             23868..25214
                     /gene="glnA"
                     /locus_tag="VVR21_001393"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU6055264.1"
                     /translation="MPITAADIRREVNEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(25304..25423)
                     /locus_tag="VVR21_001394"
     CDS             complement(25304..25423)
                     /locus_tag="VVR21_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU6055265.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         8034 a         4577 c         5765 g         7532 t
ORIGIN      
        1 aattttttgc caattattga ggaaaatatt tctaagttat taaatagtca aaaggatgaa
       61 tggaaacagc tcagttatca tcgtgaatat gttgttaaga tggcgaaggc tttatatctt
      121 caagcaaccg gaaaaacaag gcaagctcaa gatgaatgga gaaatgtgtt gaattatatc
      181 cgtgggcacg aactgctatt ccaatctaat ttggatgttt atcgtgtaat tgaagtagca
      241 aaaaattacg ctggtttcca cttataaatc ataagtatag aaaatgaacc aaggtattca
      301 gagaagattg atcctaaata ttatgaaatt taaggatttt taagatattt agggtcgact
      361 ttctatttat atcgtagcga agtcatttta ataatgatgt gtaaaagatg gatcaagatt
      421 gaggaggaag aaagatgaaa tcaaaagaag aaataaatat gcttggtttt acaattgtcg
      481 cttacgcagg agatgcaagg tcagatttga tggatgcttt ggcgtttgcg agagatggat
      541 attttgaaca ggcaagagaa ttggttgagt ctgcaaacga ctcaatagtg tctgcccatc
      601 gagaacagac taatttatta gcggaggagg catatggaga taattttgaa gtgagcttta
      661 ttatgattca tggtcaagat actttgatga caacgatgct attgtatgat caggtaaagt
      721 tttttattga tgaatatgaa cgaattcgaa agattgaaga acatattggt ttgcaatgag
      781 gattagtcat ggaaaattta cagtttaaag ccttaccgaa ggagttttta ttaggagctg
      841 ctaccgctgc ttatcaagta gagggtgcaa ctagggtaga tggcaaagga ataaatatgt
      901 gggatgttta tttgcaagaa aatagtccgt tcttaccaga tccagctagt gatttttatt
      961 atcgttacga agaggatata gctttggcgg cagaacatgg tttgcaggct ttgcgtttat
     1021 ctatttcttg ggttcgtata tttcctgata tagatgggga gccgaatata ttagctgttc
     1081 gttattacca tagagtcttt cagtcttgct taaaacataa tgtgattccg tttgtttctt
     1141 tacatcattt tgattcgcct cagaaaatgt tagaaacagg ggattggttg aatagagaga
     1201 atattgatcg tttcatacga tatgctcgct tttgtttcca agaatttaca gaagtcaagc
     1261 attggtttac aatcaatgaa ctgatgtctc ttgctgcagg tcaatatata ggaggtcagt
     1321 ttcctccaaa tcatcatttt caattatctg aagcaattca agcgaatcat aatatgttgt
     1381 tggcgcatgc tcttgcagtc ctcgaatttc atcaattagg aattgaggga gagataggtt
     1441 gtattcatgc tttaaagcca ggctatccta ttgatgggca aaaagaaaat attttagcag
     1501 ctaaacggta tgatgtttat aataataaat ttctattaga tggaactttt ttgggctact
     1561 acagtgatga cacgcttttt cacttgaatc aaatattgga agctaataat tctagcttta
     1621 ttattgaaga tggtgattta gaaattatga aaagagctgc acctcttaat acgatgtttg
     1681 ggatgaatta ttatcgttca gaatttattc gtgaatacaa aggtgaaaat agacaagaat
     1741 ttaattcaac aggaataaaa ggacagtctt cttttaaatt aaatgctcta ggtgaatttg
     1801 taaaaaagcc tggtattccg acaacagatt gggattggaa tatttatcct caagggttat
     1861 ttgatatgtt gcttcgtatc aaagaagaat atcctcaaca tccggtcatt tatttaactg
     1921 aaaatggtac agcccttaaa gaggttaagc cagagggcga gaatgatatt attgatgaca
     1981 gtaaaagaat ccgttatatt gagcaacatt tacacaaagt tttagaggct cgagataggg
     2041 gagtcaatat tcaaggctat tttatatggt ctttgcaaga tcaattttct tgggcgaatg
     2101 gctacaataa gcgatatggt cttttctttg ttgattatga aacacagaag agatatatta
     2161 agaaaagtgc tctttgggta aaaggattaa aacggaatta aggttagcga tttgactgat
     2221 gtttaatata ttttaactat gagcttaaat tttttacagg aggagttttt atggataagt
     2281 tagtcgctgc cattgaaaag caacaaggga aatttgaaaa aatttctact aataattata
     2341 tgatggctat taaagatgga tttattgcta ctatgccttt aattatgttt tcaagctttt
     2401 tgatgattat tattatgatt cctaaaaatt tcggagtaga gttaccgagt ccagctattg
     2461 cctggatgag gaaagtgtat atgctaacca tgggagtttt gggtgttatt gtttcaggga
     2521 cagttgcaaa gtcattggct ggaaatgtta atagaaaaat gcctcctgga aaggtaataa
     2581 atgatacttc tgcaatgttg gcggccatat gtggctatct tgtattaact gtaacgcttg
     2641 tagttgatga gaaaacggga tctacaagtt tgtcgacaaa ctatttagga tctcaaggat
     2701 tgataacttc gtttgtcagt gcctttatta ctgtaaatgt ttaccgattc tgtattaagc
     2761 gagacattac tattcattta cctaaggaag ttcctggggc tatatcacaa gcttttagag
     2821 atatttttcc tttttctttt gttttactta ttagtggttt gttagatatt gtatctcggt
     2881 ttagtttaga tgttcctttt gcccaagtat ttcaacaact attgactcct atttttaagg
     2941 gggcagaatc atatcctgct atgatgttga tttggtttat gtgcgctttg ctttggtttg
     3001 ttggaattca tggaccatct attgtcttac ctgctgttac agctttacaa ctgagcaata
     3061 tggaagagaa tgctcaactt cttgcaaatg ggcagtttcc ttatcattct ttaacgccta
     3121 atttcggaaa ttatatcgct gctatcggag gaacgggggc tacctttgtt gtaccattta
     3181 ttttgatttt ctttatgcgg tctaaacaat taaaatcggt aggtaaagct acaattactc
     3241 ctgttttatt tgcggtgaat gaacctcttc tatttggtat gccagttatt ttgaatccct
     3301 atctttttgt accttttttg atgactccac cagtgaatgt atttctagga aaggtcttta
     3361 ttgatttctt tggaatgaat ggattttata tccagttacc ttgggccttt cctggtccct
     3421 tgggattgtt aattggaacg aattttcaat ctatctcctt tgtattttta tctttgattt
     3481 tagttgtcga catattgatt tatttgccat tctgtagagc gtatgataga cagttactga
     3541 tgaaagaaga tgttgcaagc tcaaatgata ttattttaga ggaggagaca agtgaaataa
     3601 tgcctggtga gttagatgaa ataaaaagta aggagttgaa agtactggtt ctttgtgcag
     3661 ggtctggaac aagtgcgcaa ttagccaatg caattaacga gggcgctcaa ttagcagaag
     3721 ttagagtgat tgcgaattca ggagcgtacg gagctcatta tgatattatg ggtgtttatg
     3781 atttaattat tctggctcca caagttcgga gttattatag agagatgaag gtggatgcag
     3841 aaagattagg tattcagata gttgctacca gaggaatgga atatattcat ttaacaaaga
     3901 gtccaagtaa atccttacaa tttgtattgg agcattacca agctgtgtag taagtttttc
     3961 catcttttat ttgagtaagg attttgctta cagataggct tggatttaaa aacgttcccc
     4021 cttttttaat ataagaatcc ctctttcaca attgtaaaaa gagggatttt gtattttatc
     4081 tcttagacca agttctcttc ataaagagaa ggaggattgg gtaaatctcc aagcgccctg
     4141 caatcattgc aaaggatagg agaatttttg agatgggact aaagattgag aaactagaag
     4201 tggttcctag aataggcccg atattattga aacagctaaa gacagcgctg gtcacgacca
     4261 gaaaatcatt gctatctagg ctgacaataa agataagcgc tagcaaaatc atagcataga
     4321 tgacaaagta cttgagaatc ttatgctggg tatctttatc aatcaccgtt tgattcacat
     4381 ggagggtcaa aacacggtgg ggcgatagga ttgacaaaat ttggtttttg gcaatttttg
     4441 aaaggatgag gcctcgaata atcttgagtc cacctgcagt tgatccagca gagccaccga
     4501 ttgccatgag gaaaaggagg ataaactggg agaagagggg ccagttggta atatctccat
     4561 atccaaaacc agttgttgta atgatgttgg aaacctggaa gaaggtcatt tcaaagctct
     4621 ttgaaaaccc tgggtagagg tagagggtgt tgaggctaat caagcctgta gaaaccagta
     4681 caatgaccaa gtaagcccga agttcttcgt caccaaagaa ggccttgatg cgacggagca
     4741 tgaggtagta gtagaggttg aaatttaccc caaaaaccag aactccgata ctgaccagat
     4801 aggtaatcag tgagctgcca tagtgggcaa ttccgtcgtt atagacggta aagcctccag
     4861 ttcccgctgt ccccatagca atgacaaaac tatcgtagag aggcatacca gctagataat
     4921 agatgatgac aaagagggag aagagagcta gataaaggag atagagaatc tgggcagtgt
     4981 tttttagttt ggatacaacc ttgccaaaaa caggacctgg aacctcagcc ttcatcacct
     5041 ctaggtggct atttttggca ttgtccataa tagcaagtgc aaaaacaagc actcccatcc
     5101 ctccaatcaa gtgggtaaaa cttcgccaga agaggaggga acggctgaga accgaaacgt
     5161 cgttcaaaat acttgctcca gtagttgtaa acccagaact aatttcaaaa aaggcatcaa
     5221 taaggctggg gatttgccca gaaaagacaa aggggagacc accaaagaaa gaccaaagga
     5281 tccaacagag ggcaacgatc aagactccct ccttggcata aatccgttga ttttttggct
     5341 tctgtaaact ccctgaaccg cctaacaata cgagaatccc tatggtcgaa aagagggctg
     5401 taaagacttg gctcgattca cggtaataga cagcgatagc cacaggaacc aagaggagaa
     5461 cagcttcaat caaaagtaac tttgaaagga ggtaacgaat catactttta ttcatttctt
     5521 acctcgcaat caagtcataa atcttggtga tgtttggcaa caaggttgtt actaggagct
     5581 tgtctccaac ttccaacata tcctccccag ttgggaaaat agtcttgccc tttcgaataa
     5641 tggctgcaat aagaacctct tttttcaatt tcagttgaga aagaggtttg gcagtcattt
     5701 tattggcttc cttgatatgg aattgcaggg tttcgatttg gccattggct agatggtgca
     5761 tggcttgaag gtctgaatac tgggcattaa ctcgaccacg aataaagtgc ataatcgtat
     5821 ctacagcgat gcttttaggt gtgatgatac ttgaaaaatc aggcgcattg ataatctcga
     5881 ggagactggt acgattgacc ttagtaatat ttttctgtac acctaccctg tcaaggaaca
     5941 tagatgtaat cagattttcc tcatcgactc ctgttagagt cgcaacggca tcatagtgtt
     6001 gagcactttc ttccagcagg atatcttttg cggttccatc tccttgaacg atgtagagat
     6061 ttgggaattt ctcgctaaag aagctggcga tttcaggatt gatttcaatg acttttgtat
     6121 cgatacgact atctttgaga ataccaagta gataataggc aattctacct gccccaacga
     6181 tgagaaggct cttcacggcg cgtgatttaa aataattatg gaagagtatc atatcgacac
     6241 ggttaccagt gacaaagatt ctatctttat cctgtacagt catgtcaccg cttggaatga
     6301 taatttgatg atccctctct atcgcacaga caatgacatt accaaatttt ttacgaaaat
     6361 cagaaatggg catttggcaa agaccgctgg tggacttgac gacaaattcc atgaggctaa
     6421 cgcgtccacc agcaaagcgt tcgacagaca gggcgttggg gaagtcaatg atattcgcga
     6481 tagcgcgggc agccaagagc tcaggattaa cgataagaga aaaaccgaga atattctttt
     6541 ccttgaaata agagttagaa tattcagggt tccgcacccg aacgatagtt tctttagctc
     6601 ccattttctt ggctagaact gctgcaatca tgttgacttc atcgtgctca gtcagggcga
     6661 taaagatatc acaatcttgg acgctggctt gctcaagaat ggcaaaatcg gccccgttac
     6721 caaggatacc aatgatatca aagcgactga caatatgatt gagaacagct tcgtcttgct
     6781 caatcagcaa aacatcatgc ttttctgcaa ccaaggagcg acagagggca aaaccaactt
     6841 ttccccctcc gacaaggata attttcataa taaaacctac tttttcatga tgtaactatc
     6901 ataccctttt tcaagaaaaa atgcacctac tagctaataa caagagcttt tagtaggaaa
     6961 tttgctataa gttaaaacta taccctaacc aattgaaata gctattagcg actttctctg
     7021 aaatatggta tgataaagga tatacaagga gataaaatga ataataattt actggtatta
     7081 caatcagact ttggtctggt tgatggtgcg gtatcggcta tgattggagt ggctttagaa
     7141 gagtctccaa ccttaaaaat ccatcacttg acgcacgata tcacgcctta taatattttt
     7201 gaggggagct atcgtctctt tcagacggtg gattactggc ctgagggaac gacgtttgta
     7261 tcggttgtcg atccaggtgt cggttcgaaa cgtaagagtg tagttgccaa gactgcaaaa
     7321 aatcaataca ttgtcacgcc agataatggg acgctttcct ttatcaagaa acacgttggc
     7381 attgtagcca ttcgtgagat ttctgaggtg gccaataggc gtcaaaacac agagcattct
     7441 tataccttcc acggtcgtga tgtctatgcc tatactggtg ctaaactggc cagtggtcac
     7501 attacttttg aggaagtagg gccagagctc agtgtggaac agattgtaga gcttccagtc
     7561 gtagcgacca tcatagaaga tcatctggtg aagggagcca ttgatattct ggatgtgcgt
     7621 ttcggttcgc tttggacctc tatcacacgg gaagaatttt acaagctgga accagaattt
     7681 ggtgatcgtt ttgaagtgac catctatcat gctgatatgc tggtctatca aaatcaggtt
     7741 gtctatggca aatcatttgc agatgtgaga attgggcaac ccatccttta catcaactct
     7801 ctctatcgtt taggtttggc tatcaaccaa ggttcctttg ccaaggccta taatgtaggt
     7861 gtcggttcat cttggaccat tgaaataaag aaaatagaag gataaaatag gagaatagta
     7921 tggaaatcaa atttacaatt aaacaagttg ttgctgtcgg aattggcgct gccctctttg
     7981 tcgtcatcgg gatgatcaac attccaaccc ctgttccaaa tacaagcatc cagcttcagt
     8041 atgcggtaca agcgctactt tctattattt ttggaccgat tatcggtttg cttgtcgggt
     8101 tgattggtca tgcaatcaag gactctcttg ttggttatgg tctatggtgg acttggatta
     8161 tcgctagcgg actctttggt ttagttgtgg gactttttag aaagtacgtt cgcgtgatca
     8221 atagtgtttt tgactggaaa gatattctta tttttaatct cattcaacta cttgcaaatg
     8281 cccttgtttg gggtgtcttg gcaccacttg gagatgttgt gatttatcaa gaagcggcag
     8341 aaaaagtatt tgcacaaggg attgttgcgg gaattgccaa tggtgtatct gtagctattg
     8401 caggaactct tctcttactt gcctatgcag gaacccaaac tcgtgcagga agtttgaaaa
     8461 aggactaata ctcaatgaaa atcaaagagc aaactaggaa gttagccgca ggttgctcaa
     8521 aacagtgttt tgagattgtg gatagaactg acgaagtcag ctcaaaacat ggttttgagg
     8581 ttgtagatga aactgacgaa gtcagtaacc atacctacgg caaggcgaag ctgacgtggt
     8641 ttgaagagat tttcgaagag tataaaatga tggggaaggc tgggcaacta gtctttttcg
     8701 atgtttatag attagttagg caagtaagct aggataggaa tctttttggc gctaagattt
     8761 taagagaaga gactgcaaga agggcttgat ttatgataaa atagaagtct aagaagcgaa
     8821 tgaagagagt aagatgaaag aagctataat tgagtggaag gatttctctt tccggtatga
     8881 aacacaacaa gaaccgacct tgcaagggat agacttgacc atttacaagg gagagaaagt
     8941 cttaattgtt ggaccatctg ggtcaggtaa atctaccttg ggtcagtgtt tgaatgggat
     9001 tattcccaat atttacaagg gtcagacata tggagaattt ttgataaagg gtcaagtagc
     9061 ctttgatatg agcatctatg ataagtctca tctggttagc acagttttgc aggatacaga
     9121 tgggcagttt attggcttgt ctgtggcaga agatttggcg tttgctctgg aaaatgatgt
     9181 gacagcccta gatgagatga aaggtcgtgt ttataaatgg gctgaaaagc tggaccttct
     9241 tcctttactg gatcagcgtc ctcaggattt gtcaggtgga caaaagcagc gagtcagtct
     9301 ggctggtgtc ttgattgatg aaagtccgat tctcttgttt gatgagccac tcgccaatct
     9361 agatcccaaa tcaggtcagg atattatcga attgattgac cagattcata aggaagaggg
     9421 gacgacgact ctgattatcg agcaccgttt ggaggatgtt ctgcatcgcc ctgtggatcg
     9481 gattgtcttg ataaacgatg gtcgtatcct ttttaatggg agccctgacc agttgcttgc
     9541 gactgattta ttgactcaaa atggaattcg agaacccctt tatctaacga ctctccgtca
     9601 attaggtgtg gacttagtca aggaagaaca gttagcgaat ctggataaca tgtctatctc
     9661 aaaaggtcag gttcagctgc agaatgaact ggcaaaagaa actccagaat tgcagtcact
     9721 ctttaaatta gaggacgtgt ctttctctta tgatgataga ccgattttaa aatccctaca
     9781 tttagatatt aaaaagggtg aaaagattgc tattgtcgga aaaaatggag cagggaagtc
     9841 aactctagcc aaggccttga gtagctttat ccagactgaa ggccgctatc tttgggaagg
     9901 acaggatata aaaggagatt ctgttgcaga gcgggcggaa cgagtaggct atgtgctgca
     9961 aaatcccaat caaatgattt caaccaatat gatttttgat gaggtggctc tgggactccg
    10021 tttgcgaggt gtggacgagc aggaaattga aacgagagtc tatgaaacct tgaaaatctg
    10081 tggtctctat gaattccgta attggcccat ttctgccctg tcatttggtc agaaaaaacg
    10141 tgtgactatt gcctcaattt tggtcttagg cgctgaaatt atcctcctag atgaaccgac
    10201 tgcgggtcaa gaccagaaga actatactga gattatggaa tttctcgaag aactgcatca
    10261 acaagggcat accattgtca tgattaccca tgatatgcaa ttgatgctgg attattcaga
    10321 tcgagtcctt gtcatggtgg atggagaatt gattgccgat actgttccag ccagtctgtt
    10381 gagcgatcct gagctgttag taaaagccaa tctaaaagaa acctccatct ttaacttggc
    10441 taagaaacta gatgtggatc cactggattt aacggcattt tacaaagaaa ggagagaggg
    10501 atgcaagcta aattaatcgg ttaccagcat agagatactg tgattcatcg cttgtcagga
    10561 gctgggaaac ttctcttttt cattctggta tcattggcgg ccatgattag ctatgatacc
    10621 agaatgctct tgctgattgc catcttttca gtctttctcc tctatacgat ttctgctgag
    10681 tgggatagag atggtggtga tgaactatat catctctatg cgcaagcttg cgaggaaaga
    10741 aagatttact ctgtttttga tttaaaagat cgtatcctag ctcaagatgg gtatgaagca
    10801 aaatggtata actggtgtga tggttttaat caagcagcaa ctcttttgtt gaaaaggtag
    10861 tgcattgtgt tttgttcctt attataaggt caatcattgt gaggaagctt ttgcttggta
    10921 tcaggatgtg aacttggttt acctcgtaga tggggtgaag cttccttaca gtcaagcgac
    10981 cttggaagcc atgtattcct atttggattg gcatggtgag cttttttgga ttgaagtcaa
    11041 ggagaaggga gaatggtttc caattgggga tattacacta tctcaggata atctccccat
    11101 tgtgattggg aattccgctt accaacatcg aggacttgga aaaaagattc taagtgcttt
    11161 gattgaattg gctcgagtaa aaggatggaa agaattgaga gtcaaggaaa tctacaccta
    11221 caatcatgct tctaggaggt gtttcaagtc gcttggattt gtggaaaatg gagcaacaga
    11281 aaaaggaagg agttttatat tggaattagt ctaatcctgc cactttctcc cccttaacct
    11341 ttgactattc cgcaaaatta tcgtaaaata aagagtaaat gataaaatga ggtcagagtc
    11401 tgttcgctct gacgatagta gtataaatga ggagaaacgc tttggaatta gaagtatttg
    11461 ctgggcaaga aaaaagtgaa ctatctatga ttgaggtagc gcgtgctatc ttagaacttc
    11521 gtggtcgcga tcatgagatg cattttagcg atcttgtaaa cgaaattcaa aactaccttg
    11581 gaacatcaaa cagcgatatc cgcgaagctt tgcctttgtt ctacacagag ttgaactttg
    11641 acggtagctt catctcactt ggggacaaca aatggggtct tcgttcatgg tatggtgtgg
    11701 acgaaatcga cgaagaaatc atcgctcttg aagaaaatga cgacgatgaa gtagcaccaa
    11761 aagctaagaa aaaacgtgtc aatgccttta tggatggtga ttcagatgcc attgactaca
    11821 atgcagatga tccagaagac gaagatgcat acgaagcaga tccagctctt tcatacgatg
    11881 atgaaaatcc agatgatgaa aaaaatgaag tggaagctta tgatgcagaa atcaacgaaa
    11941 tcgctccaga tgacttggga gaagatgtgg atctcaacga agacgacgac gagttttcag
    12001 atgacgacgc tgaaaccagc gaggaataag agttagctat tgacaattat cctattttta
    12061 ggtatcatat tgtttgggca cctcttttag aggtcggggc tccctagttc ttagggagct
    12121 atttttgttt tttcaagaag ttatcttctt gtattttata ctcaatgaaa atcaaagagc
    12181 aagctaggaa actagccgta ggctgctcaa aacactgttt tgaggttgta gataagactg
    12241 acaaagtcag gaacacatat ctacggcaag gcgacgttga cgcggtttga agagattttc
    12301 gaagagtatt agttgtgaat ctggtgcagt cgtcccagat tattcttatt agtagggtct
    12361 tgttttctat atcccctcgt agttaacaag accttgagca ttttagaaag aggaatctat
    12421 gtctacgaaa tatatttttg taactggtgg tgtggtatcg tctattggga aagggattgt
    12481 ggcagcgagt ctaggccgtc tcttgaaaaa tcgtggtctc aaagtaacca ttcaaaagtt
    12541 tgacccttat atcaatattg atccgggaac catgagtcct taccagcacg gggaagtttt
    12601 tgtgacagat gacggagctg agacagattt ggacttgggt cactatgaac gtttcatcga
    12661 tatcaatctc aacaaatatt ccaacgtgac aactgggaaa atttacagtg aagttcttcg
    12721 taaagaacgc cgtggagaat accttggggc aactgttcaa gtcattcctc atatcacaga
    12781 tgctttgaaa gaaaaaatca agcgtgccgc tctaacgacc gactctgatg tcattatcac
    12841 agaggttggt ggaacagtag gagatatcga gtccttgcca ttcctagagg ctcttcgtca
    12901 gatgaaggca gatgtgggtg cggataatgt catgtatatc catacaacct tgcttcctta
    12961 cctcaaggct gctggtgaaa tgaaaaccaa accaacccaa cactctgtca aagaattgcg
    13021 tggcttggga atccaaccaa atatgttggt tattcgtaca gaagagccag ctggtcaagg
    13081 aattaaaaat aaactggccc agttctgtga tgtggcacca gaagccgtta tcgaatcgtt
    13141 ggatgttgaa cacctttacc aaattccact gaacttgcag gcacaaggga tggaccaaat
    13201 tgtttgtgat catttgaaat tagacgcacc agcagcggat atgacagaat ggtcagccat
    13261 ggtggacaag gtcatgaacc tcaagaaaca agttaagatt tcccttgttg gtaagtatgt
    13321 ggagttgcaa gatgcctata tctcagtggt cgaagccttg aaacactctg gctatgtcaa
    13381 tgatgtagaa gttaaaatca attgggtcaa tgccaatgat gtgacagcag agaatgtagc
    13441 agaactcttg tctgatgcgg acgggatcat cgtaccaggt ggttttggtc aacgtggtac
    13501 agaagggaaa atccaagcca tccgctatgc gcgtgaaaat gatgttccaa tgttgggagt
    13561 ctgcttggga atgcagttga catgtatcga gtttgctcgt cacgttttag gtcttgaagg
    13621 tgccaattct gcagagcttg caccagaaac aaaataccct atcattgata tcatgcgtga
    13681 tcagattgat attgaggata tgggtggaac ccttcgtttg ggactttatc cgtctaagtt
    13741 gaaacgtggc tctaaggctg ctgctgctta tcacaatcaa gaagtggtgc aacgccgtca
    13801 ccgtcaccgt tatgagttta ataatgcctt ccgtgagcag tttgaggcag caggttttgt
    13861 cttttcagga gtttctccag acaatcgttt ggtagaaatc gtggaaattc ctgaaaataa
    13921 attctttgta gcttgtcagt atcaccctga actgtcaagc cgtccaaacc gaccagaaga
    13981 actctacact gcctttgtta ctgcagcggt tgagaacagc aattagcaaa atcagaacct
    14041 ttgagaaaaa tctcagaggt tttttgcata caatgatatt gcagtatatc tgaggtagga
    14101 gtcctctgta tgtacctgct accgttgaaa ttaatagcga ctccctcttg ccctgtgcta
    14161 gtgaatggat ttatcagtat attgaaatga aataaaatct gaacaaatta attcggaaag
    14221 ccaaatcaat ttctagcaaa gttttaggaa ctggattgta tagtgaattg aaataagatg
    14281 tgaacatctc tatcagaaaa gtcaaattaa tttatagaaa tattttagca gtcaagatgt
    14341 actgttatag attcaataca ttatactttt ttaatttaat ccactatagt aaaatgaaat
    14401 aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaaatag
    14461 aggtgtacta ttctagtttc aatatactat atatctgcag aatactcttt cagtttcatt
    14521 cagcctagtc ttgcttagga aaaagtaaaa agccatccaa ttatgatgga tagcttcttg
    14581 gttcttagat ttgttctgca aaaacctttt cagcaaggtt catagcgtgg tctgatacac
    14641 gagtgtagtg tgagatgatg tcgataaagt tgaccccagc ttgtgttgaa cattcgcctt
    14701 tgttgaggcg tttgatgtgg gtttttctga gaacacgttc tatcttattg attgcttcat
    14761 gacgttctac aagactgcgt gctttttcaa tatcattgtt ttccacacta tccagagcat
    14821 ctttgataaa gtcactagtt tggcggtaaa cttcctctaa ttctttcaag gcggcatcgg
    14881 aaaattcaac atttttccgt tgaagatagg cagtcagatt gagtagagcc tccgtgtggt
    14941 ctccaatccg ttccaaatca cgggaggaat caaggatatt ggtgagcact tcactttctt
    15001 tttggctgag agcttcgctt gaaagggcaa tgagataacg tgttaattgc tcatcgatgg
    15061 tgttaattgc ttcttcggtt ttatgccctt tttcagcaac tttttcatcc aagtcaatga
    15121 tgtacttata ggaaaggtca aaggctttag cagcgtagtt tcctaagtgc aagagctctt
    15181 ttttagcatt tcctagagcg atagatgggg cttgtttgat gaaatgttca tcaagatata
    15241 agggttcgta tttgacaacc tcgtcctctc caggaataat cttggttaca aagtaagcca
    15301 gagctccgat aaatggaaat tggacaatgg tgttggtaat attaaaggtt ccgtgagcaa
    15361 aggcgatggt catttccggt gctagattta gcgtagcttc aaaccaatga atcaggacag
    15421 taaaaggaac tagaaaaata acgcagacaa ctgttccgat aacgttgaag gcaacatgag
    15481 ctcctgctac ccgtttagct gcaatattag cccctaaaga ggcaatgatg gctgtaatgg
    15541 ttgtcccgat attgtcacca aatagaactg gcaaagctcc ctgtagatca attagattgc
    15601 cggcgtagag gttttgtaaa atcccaatgg tagccgaaga agcttgaatt agcaaggtca
    15661 agccagtacc gacaaagaca cccaaaacag gattcttact tagctcaatc atatagtcct
    15721 taaagacctg taaatccttg agtggagcca ttgcgctgct catgagattg agggcaaaaa
    15781 agataccacc gacaccaaag aggatgcgtc cgatattatt gactgtccga tttttcgtaa
    15841 aaaagagaca gacggcaccg ataaagagca taggtagggc atagttacct aatttaaaac
    15901 cgatgagaaa ggatgtgaca gttgtcccaa tattagcacc catgacaatc ccgatagcct
    15961 gacgtaaggt taagagaccg gcactgacca ggccgactgt gataactgtt acaccagaac
    16021 tagactgaat tagagcagtc atcccaatac caaccagaac tccaaagaaa ggattactag
    16081 tatatttgtc aatgtaaaaa cgaaggcgat ctccagcagc ttgttgtaaa ccgtctccca
    16141 tggtcttgat gctatataag aatagcccca gaccacctaa aaagtgaaat aaaatttcct
    16201 gccaattaat ggacatttct ttttcctccg aaaaataatc gcggaatatc tcctattcta
    16261 ttttaaagga taaaagtaaa tctaacaagt gttaatgtca agtttgtaaa agaaaattat
    16321 aattgataag tgtattattt ttaagagttt ttaaccttat tttagatttg tgcaaacagt
    16381 tattgttttt tgtctaaaaa tgttttagga taaaaatgtg attatcatgg ttctagagtt
    16441 tgataaaaaa ctacagaata taaagcgctt tcttgaaaac aacaaaatca atcttttagg
    16501 aggagaaaat gaagaatcca ttttttgaaa gacgttgtcg ttacagtatt cgtaagttat
    16561 cagtaggagc ctgctcgctg atgattggtg ctgttttatt tgctggtcca gccttggctg
    16621 aagaaactgc agttcctgaa aatagcggag ctaatacaga gcttgtttca ggagagagtg
    16681 agcattcgac caatgaagct gataagcaga atgaagggga acatgctaga gaaaacaagc
    16741 tagaaaaggc agaaggagta gcgacagcat ctgaaactgc agaagcagct agcgcagcta
    16801 aaccagagga aaaagcaggt gaggtggttg cagaaacacc atctgcagaa gcaaaaccta
    16861 agtctgacaa ggaaacagaa gcaaagcccg aagcaactaa ccaaggggat gagtctaaac
    16921 cagcagcaga agctaataag actgaaaaag aagtccagcc agatgtccct aaaaatacag
    16981 aaaaaacatt aaaaccaaag gaaatcaaat ttaattcttg ggaagaattg ttaaaatggg
    17041 aaccaggtgc tcgtgaagat gatgctatta accgcggatc tgttgtcctc gcttcacgtc
    17101 ggacaggtca tctagtcaat gaaaaagcta gcaaggaagc aaaagttcaa gccttatcaa
    17161 acaccaattc taaagcaaaa gaccatgctt ctgttggtgg agaagagttc aaggcctatg
    17221 cttttgacta ttggcaatat ctagattcaa tggtcttctg ggaaggtctc gtaccaactc
    17281 ctgacgttat tgatgcaggt caccgtaacg gggttcctgt atacggtaca ctcttcttca
    17341 actggtctaa tagtattgca gatcaagaaa gatttgctga agctttgaag caagacgcag
    17401 atggtagctt cccaattgcc cgtaaattgg tagacatggc caagtattat ggctatgatg
    17461 gctatttcat caaccaagaa acaactggag atttggttaa acctcttgga gaaaagatgc
    17521 gccagtttat gctctatagc aaggaatatg ctgctaaggt aaaccatcca atcaagtatt
    17581 cttggtatga tgccatgacc tataactatg gacgttacca tcaagatggt ttgggagaat
    17641 acaactacca attcatgcaa ccagaaggag ataaggttcc ggcagataac ttctttgcta
    17701 actttaactg ggataaggct aaaaatgatt acactattgc aactgccaac tggattggtc
    17761 gtaatcctta tgatgtattt gcaggtttgg aattgcaaca gggtggttcc tacaagacaa
    17821 aggttaagtg gaatgacatt ttagacgaaa atgggaaatt gcgcctttct cttggtttat
    17881 ttgccccaga taccattaca agtttaggaa aaactggtga agattatcat aaaaatgaag
    17941 atatcttctt tacaggttat caaggagacc ccactggcca aaaaccaggt gacaaagatt
    18001 ggtatggtat tgctaaccta gttgcggacc gtacgccagc ggtaggtaat acttttacta
    18061 cttcttttaa tacaggtcat ggtaaaaaat ggttcgtaga tggtaaggtt tctaaggatt
    18121 ctgagtggaa ttatcgttca gtatcaggtg ttcttccaac atggcgctgg tggcagactt
    18181 caacagggga aaaacttcgt gcagaatatg attttacaga tgcctataat ggcggaaatt
    18241 cccttaaatt ctctggtgat gtagccggta agacagatca ggatgtgaga ctttattcta
    18301 ctaagttaga agtaactgag aagaccaaac ttcgtgttgc ccacaaggga ggaaaaggtt
    18361 ctaaagttta tatggcattc tctacaactc cagactacaa attcgatgat gcagatgcat
    18421 ggaaagagct aaccctttct gacaactgga caaatgaaga atttgatctc agctcactag
    18481 caggtaaaac catctatgca gtcaaactat ttttcgagca tgaaggtgct gtaaaagatt
    18541 atcagttcaa cctcggacaa ttaactatct cggacaatca ccaagagcca caatcgccga
    18601 caagcttttc tgtagtgaaa caatcgctta aaaatgccca agaagcggaa gcagttgtgc
    18661 aatttaaagg caacaaggat gcagatttct atgaagttta tgaaaaagat ggagacagct
    18721 ggaaattact aactggctca tcttctacaa ctatttatct accaaaagtt agccgctcag
    18781 caagtgctca gggtacaact caagaactga aggttgtagc agtcggtaaa aatggagttc
    18841 gttcagaagc tgcaaccaca acctttgatt ggggtatgac tgtaaaagat accagcctac
    18901 caaaaccact agctgaaaat atcgttccag gtgcaacagt tattgatagt actttcccta
    18961 agactgaagg tggagaaggt attgaaggta tgttgaacgg taccattact agcttgtcag
    19021 ataaatggtc ttcagctcag ttgagtggta gtgtggatat tcgtttgacc aagccacgta
    19081 ccgttgttag atgggtcatg gatcatgcag gagctggtgg tgagtctgtt aacgatggtt
    19141 tgatgaacac caaagacttt gacctttatt ataaagatgc agatggtgag tggaagctag
    19201 ctaaggaagt ccgtggtaac aaagcacacg tgacagatat cactcttgat aaaccaatca
    19261 ctgctcaaga ctggcgcttg aatgttgtca cttctgacaa tggaactcca tggaaggcta
    19321 ttcgtatcta taactggaaa atgtatgaaa agcttgatac tgagagtgtc aatattccga
    19381 tggccaaggc tgcagcccgt tctctaggca ataacaaggt acaagttggc tttgcagatg
    19441 taccggctgg agcaactatt accgtttatg ataatccaaa ttctcaaatt ccgctcgcaa
    19501 ccttgaagag cgaagttgga ggagacctag caagtgcacc attggatttg acaaatcaat
    19561 ctggtcttct ttattatcgt acccagttgc caggcaagga aattagtaat gtcctagcag
    19621 tttccgttcc aaaagatgac agaagaatca agtcagtcag cctagaaaca ggacctaaga
    19681 aaacaagcta cgccgaaggg gaggatttgg accttagagg tggtgttctt cgagttcagt
    19741 atgaaggagg aactgaggac gaactcattc gcctaactca cgcaggtgta tcagtatcag
    19801 gttttgatac gcatcataag ggagaacaga atcttactct ccaatatttg ggacaaccag
    19861 taaatgctaa tttgtcagtg actgtcactg gccaagacga agcaagtccg aaaactattt
    19921 tgggaattga agtaagtcag gaaccgaaaa aagattacct agttggtgat agcttagact
    19981 tgtctgaagg acgctttgca gtggcttata gcaatgacac catggaagaa cattccttta
    20041 ctgatgaggg agttgaaatt tctggttacg atgctcaaaa gactggtcgt caaaccttga
    20101 cgcttcatta ccaaggccat gaagttagct ttgatgtttt ggtatctcca aaagcagcat
    20161 tgaacgatga gtacctcaaa caaaaattag cagaagttga agctgctaag aacaaggtgg
    20221 tctataactt tgcttcatca gaagtaaaag aagccttctt gaaagcaatt gaagcggccg
    20281 aacaagtgtt gaaagaccat gaaattagca cccaagatca agtcaatgac cgacttaata
    20341 aattgacaga agctcataaa gctctgaatg gtcaagagaa atttaaggaa gaaaagacag
    20401 agcttgatcg tttaacaggt gaggttcaag aactcttggc tgccaaacca aaccatcctt
    20461 caggttctgc cctagctccg cttcttgaga aaaacaaggc cttggttgaa aaagtagatt
    20521 tgagtccaga agagcttgca acagcgaaac agagtctaaa agatctggtt gctttattga
    20581 aagaagacaa gccagcagtc ttttctgata gtaaaacagg tgttgaagta cacttctcaa
    20641 ataaagagaa gactgtcatc aagggtttga aagtagagcg tgttcaagca agtgctgaag
    20701 agaagaaata ctttgctgga gaagatgctc atgtctttga aatagaaggt ttggatgaaa
    20761 aaggtcaaga tgttgatctc tcttacgctt ctattgtgaa aatcccaatt gaaaaagata
    20821 agaaagttaa gaaagtattt ttcttacctg aaggcaaaga ggcagtagaa ttggcttttg
    20881 aacaaacgga tagtcatgtt atctttacag caccacactt tactcattat gcctttgttt
    20941 atgaatctgc tgaaaaacca caacctgcta aaccagcacc acaaaacaaa gtccttccaa
    21001 aacctactta tcaaccggct tctgatcaac aaaaggctcc taaattggaa gttcaagagg
    21061 aaaaggttgc ctttcatcgt caagagcatg aaaatgctga gatgctagtt ggggaacaac
    21121 gagtcatcat acagggacga gatggactgt taagacatgt ctttgaagtt gatgaaaacg
    21181 gtcagcgtcg tcttcgttca acagaagtca tccaagaagc gattccagaa attgttgaaa
    21241 ttggaacaaa agtaaaaaca gtaccagcaa tagtagctac acaggaaaaa ccagctcaaa
    21301 atacagcagt taaatcagaa gaagcaagca aacaattgcc aaatacagga acagctgatg
    21361 ctaatgaagc cctaatagca ggcttagcca gccttggtct tgctagttta gccttgacct
    21421 tgagacggaa aagagaagat aaagattaaa tatcgaaaaa tcttgtgaaa tctttcctta
    21481 tatttccaaa gtgtgatata atagtttcga ataaaataaa taaaggagtt tttgtaacat
    21541 ggcaaaactt actgttaaag acgttgactt gaaaggtaaa aaagtcctcg ttcgtgttga
    21601 cttcaacgta ccattgaaag atggcgtaat cactaacgat aaccgtatca cagcagctct
    21661 tccaactatt aagtacatca tcgaacaagg tggacgtgca attcttttct ctcaccttgg
    21721 acgtgtgaaa gaagaagctg ataaagctgg caaatcactt gctcctgtag cagctgactt
    21781 ggcagcaaaa cttggtcaag atgttgtttt cccaggtgtc actcgtggtg ctgaattgga
    21841 agcggcaatc aacgctcttg aagatggaca agttctcttg gttgaaaaca ctcgttacga
    21901 agatgttgac ggcaagaaag aatctaaaaa cgatcctgaa cttggtaaat actgggcatc
    21961 acttggagat ggtatcttcg taaacgatgc attcggtaca gctcaccgtg cacacgcatc
    22021 taacgttggt atctcagcaa acgttgaaaa agcagttgct ggtttccttc ttgaaaacga
    22081 aattgcctac atccaagaag cagttgaaac tccagagcgt ccattcgtgg ctatccttgg
    22141 tggttcaaaa gtttcagaca agattggtgt tatcgaaaac ttgcttgaaa aagctgacaa
    22201 agtccttatc ggtggtggta tgacttacac attctacaaa gcacaaggta tcgaaatcgg
    22261 taactcactt gtagaagaag acaaattgga tgttgcgaaa gctcttcttg aaaaagcaaa
    22321 cggtaaattg atcttgccag ttgactcaaa agaagctaac gcatttgctg gttacactga
    22381 agtgcgtgac actgaaggtg aagcagtttc tgaaggcttc cttggtcttg atatcggtcc
    22441 aaaatctatc gctaaatttg acgaagcttt gactggtgcc aaaacagttg tatggaacgg
    22501 acctatgggt gtatttgaaa acccagattt ccaaactggt acaatcggtg tgatggacgc
    22561 tatcgtgaaa caaccaggtg ttaaatcaat catcggtggt ggtgactcag ctgctgcagc
    22621 gatcaacctt ggacgtgcag ataagttctc atggattagt acgggtggtg gagcatcaat
    22681 ggaacttctt gaaggtaagg ttcttccagg acttgcagcc ttgacagaaa aataagattt
    22741 tataaacaaa tcaaagaaga gagggatgaa agttcctctt ttcttttgct taaaataaaa
    22801 acgcttcctc tcaactatta ctcataaaaa tcaccgattt atgataaaat ggaaatagaa
    22861 agttgagatt atgagttatt ttaaaaaata taaattcgat aaatcccagt tcaaacttgg
    22921 tatgcgaacc tttaaaacag gtattgctgt ttttctagtt ctcttgattt ttggcttttt
    22981 tggctggaaa ggtcttcaaa ttggtgcttt gacagccgtt tttagcctga gggagagttt
    23041 tgatgagagt gttcattttg ggacttcgcg tattctagga aatagtatcg gtggactcta
    23101 tgccttggtc ttcttcttat taaatacttt tttccacgaa gccttttggg tgaccttagt
    23161 agttgttcca atctgcacca tgttaaccat tatgacaaat gtagccatga ataacaaagc
    23221 aggggttatt ggtggtgtag cagctatgtt aatcattacc ctatcaattc caagtggtga
    23281 gacaattttg tacgtgtttg tacgtgtatt agaaacgttt atgggagttt ttgtcgcaat
    23341 tatcgtaaat tacgatattg atcgtattcg tctcttttta gagaaaaaag aaaaataatg
    23401 ttacatttta taacattatc aattgacgtt tgtctttttt tagactataa tagacagaaa
    23461 gaaggaaatt gtaaatgaag gaaaaagaat ttcgccgaaa tatggctgtt tttcctatcg
    23521 gcagtgttat gaagttgacc gatttatcgg cgcgtcagat tcgttattat gaagatcaag
    23581 agttgatcaa gcccgatcga aacgaaggaa atcgtcgcat gtattccttg aatgacatgg
    23641 atcgtctgct tgaaatcaaa gattatatct ctgaaggtta taatatcgct gccattaaga
    23701 aaaaatatgc tgaacgtgaa gcgaaatcca agaaagcggt tagtcagact gaagtacgtc
    23761 gtgcacttca caatgaactc ctccaacagg ggcgttttgc ttcagtacag tcaccttttg
    23821 gtcgcggtta ggcaaccgca agtagtcata gattaaggag aaaacttatg ccaatcacag
    23881 ctgcagatat tcgtcgtgaa gtcaatgaaa aaaatgttac ctttattcgt cttatgttct
    23941 cagatatttt gggaaccatg aaaaacgtcg aaattcctgc tacagatgaa cagttagata
    24001 aggtcttgtc gaacaaggtt atgtttgatg gatcttctat tgaaggtttt gtacgtatca
    24061 atgagtcgga tatgtacttg tacccggact tggatacatg gacagtcttc ccttggggag
    24121 atgaaaatgg aagtgttgca ggtctgatct gtgatgttta tacaacagaa ggtgaaccat
    24181 ttgcgggtga ccctcgtggt aatttgaaac gagctcttcg tcacatggaa gaagttggat
    24241 tcaaatcctt caaccttggt ccagagccag aattcttcct atttaagttg gatgaaaatg
    24301 gggacccaac acttgaagtg aatgacaagg gtggctactt tgatttggca cctactgacc
    24361 ttgcggacaa cacacgtcgt gagattgtga atgtcttgac caaaatggga tttgaagtag
    24421 aagcgagtca ccacgaggtt gcggttggac agcatgagat tgactttaag tacgatgaag
    24481 ttctccgtgc ttgtgataag attcaaatct ttaaacttgt tgttaaaacc attgctcgca
    24541 aacacggact ttacgcaaca tttatggcga agccaaaatt tggtattgct ggctcaggta
    24601 tgcactgtaa tatgtccttg tttgatgcag aaggaaataa cgccttcttt gatccaaatg
    24661 atccaaaagg aatgcagctg tcagaaacag cttaccattt cctaggcggt ttgatcaagc
    24721 atgcttacaa ctatactgcc atcatgaatc caacagttaa ctcatacaaa cgtttggttc
    24781 caggttatga agcgcctgtt tacattgctt gggctggtcg taaccgttcg ccacttgtgc
    24841 gcgtacctgc ttcacgtggt atgggaactc gtcttgagtt gcgttcagtg gatccaatgg
    24901 cgaaccctta cattgctatg gctgttcttt tagaagttgg tttgtatggt attgaaaata
    24961 aaatcgaagc accagctcct atcgaagaaa atatctacat catgacagca gaagagcgca
    25021 aggaagctgg tattacagac cttccatcaa ctcttcacaa cgctttgaaa gctttgacag
    25081 aagatgaagt ggttaaagct gctctcggag atcacatcta cactagcttc cttgaagcca
    25141 aacgaatcga atgggcaagt tatgcaacct tcgtttcaca atgggaaatt gataattatt
    25201 tagaccttta ctaatataga agaaagattg cctgtgggta aacagtcaca cagcagtcta
    25261 agccatcaaa tacctataac ccttaaaata gcgatttcgg tcgctattta tttttcgaaa
    25321 aatcctcttg actcttttgc gaattagatt tatcatcaga cgtgtagaag aaaatcaagg
    25381 agtcactatg gaaaaattca atttcaaaaa caatatcggg caagaaaaca agttacttca
    25441 aatcgaaatc tacaagttta ctaacttttg caagcttcaa aattacacat ctgtaaatat
    25501 tttttcgaaa gatatatttg aagccatagt aaattgagac tagaatagta cactacatct
    25561 gctaaaaatt tctagaaact aatttaactt tcctaatcga tttgtttaca tcttatttca
    25621 atctactata ttatctcaat aaatgatgat ggcgactgtt ttgtttgtgc ttgtcgattt
    25681 ttgaatcctg atcgagcgga agaatatttc tgccgaggtt gccaagggga aaatcctgaa
    25741 gatattgaat tttatgatga acaattacag gcagaaaagg tggaggtttt gaatattcga
    25801 ttggaagtaa aaaattgaat tatctacaat ctcatcaaca ataaacctat ttcaacccca
    25861 ttatctatag gcgtattttt acgccttttt atatacttga agcacata
//
LOCUS       DAVHSI010000029        24906 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.029, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000029 DAVHSI010000000
VERSION     DAVHSI010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.029"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            354..1307
                     /locus_tag="VVR21_001395"
     CDS             354..1307
                     /locus_tag="VVR21_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU6055266.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIKRWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRG
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            1628..1762
                     /locus_tag="VVR21_001396"
                     /pseudo
     CDS             1628..1762
                     /locus_tag="VVR21_001396"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2000..3261)
                     /locus_tag="VVR21_001397"
                     /pseudo
     CDS             complement(2000..3261)
                     /locus_tag="VVR21_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3268..3729)
                     /locus_tag="VVR21_001398"
                     /pseudo
     CDS             complement(3268..3729)
                     /locus_tag="VVR21_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
     gene            complement(3732..4334)
                     /locus_tag="VVR21_001399"
     CDS             complement(3732..4334)
                     /locus_tag="VVR21_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003094863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055267.1"
                     /translation="MSNIKAKINSKIDNLPDGAVFISNDFLELADYETIRKNLNRFVN
                     EGTIQRIVNGVYYKPRFIELIGEYESPSINEVAIAIARKYNWTIAPSGNTALNLLGLS
                     TQVPAQWTYISDGRYVNFIIGNTKLVFKRTTNSTISNMSQLTALVIQAIKAIGKDNIS
                     EEQILYLKNRLTISDKEKLLEEGKATSAWIYKVLKKIGES"
     gene            complement(4402..7203)
                     /locus_tag="VVR21_001400"
     CDS             complement(4402..7203)
                     /locus_tag="VVR21_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6055268.1"
                     /translation="MKEDKKLVKQARQNFRSNLKSARMHYRKEVRTLKQTVPKKGRFR
                     KPAQNSLFQDKKTELKQNLLGSQKEAEEKFLKEITYVSPRLLRVKEIKNYRLPQAQER
                     LRTAKKQLSEVKLDEKQKAVNPKFLFQKENPSSKSHFQFHQEKSFDRLSAEKEVRSAK
                     REVKQLKKVRKSKKNSTKVKGGLGLAISESLDLVAQDDDLDGLRTIKDTSLKARRYGR
                     FTYQAGKVAVKSGQTSVRFTKTKVAHGKERFHNFKKGKGFTRQKPLKSRRRYQTFLKH
                     ARKHSLAGIKGIAQAIKGSLTFFSAIAGNPLTWIVSGILLILLLMMSFFMSVSGSSVI
                     QQDEMELTKAYTHMTWEDAEHTRTNEKGITYYTKVDDVMVYMNHQYQDYKLDDVKETG
                     GAIYKAFLSQVWTDLNGGDSIKSMSDLYKEPSYKLSDEDQEELKELTEEGNYLALQEL
                     DNPFQGQTDEDSLNMSYRYGYEVIDEKPTLHHHIILEAKEDQVIVAPMDGKVSLDGEN
                     VILTSGKGVNRTKLTLFGIHSGRVSENQQVLAGDIIGQNKDGTGLKVTYQKVDDDTDK
                     LVYVNPAFYFPKVIQVQTTILPTIGQFGGDEFERAKAIYDYLKSEGATNQAIAAILGN
                     WSVESSINPKRAEGDYLSPPIGATDSSWDDEGWLSLNGPTIYNGRYPNILKRGLGLGQ
                     WTDTADGSRRHTLLLEYAKGKHQKWYDLGLQLDFMLHGDSPYYSNWLKDFFKNSGSPA
                     SLAQLFLIYWEGNSGDKLIERQTRATEWFYQIEKGFSQPNGGTAQSDPKSLEAVRGDL
                     FENSIPRGGDGMGYAYGQCTWGVAARINQLGLKLKGKNGEKIPIISTMGNGQDWVRTA
                     ASLGGETGTIPQAGAILSFAGGGHGTPTEYGHVAFIEKVYPDGSFLISETNYNGNPNY
                     TFRKLSGVDSSLSFAYTTK"
     gene            complement(7205..9530)
                     /locus_tag="VVR21_001401"
                     /pseudo
     CDS             complement(7205..9530)
                     /locus_tag="VVR21_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734154.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(9487..9840)
                     /locus_tag="VVR21_001402"
     CDS             complement(9487..9840)
                     /locus_tag="VVR21_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEU6055269.1"
                     /translation="MNTRVFKDISKVQHRAWLGFTTRQVVFVFPAVAITIMVLGLNLF
                     YWQFGDWFVYGFVFSFTIPLMLFGVYRPNDLPFETYLKYRFHYELTVPDRTFTGRKGD
                     QREKIKPLNETKDLF"
     gene            complement(9902..10756)
                     /locus_tag="VVR21_001403"
     CDS             complement(9902..10756)
                     /locus_tag="VVR21_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEU6055270.1"
                     /translation="MMMNFTSPFVFLASEKVSSDSLFEGFQVDLETTANLVKSLADFN
                     PTVWSYMTAITKGIMQPLGVAILAVVLVLEFSKMAKKIANSGGAMTFEAIAPMIVSYI
                     MVAVVITNTTVIVEAIIALASYVIEQVAGLVTNGGASYDTISGIKGSGIVGKMIIGFF
                     AILIWLVRMVSIMVVNILITIRFIQLYLMIPFAPVTIPTFLSDDWRSVGIGYLKNIMV
                     YAVQGILIFLIVSLVPLFESAGKIAVSNGAGVMESLAIMFGGLVQAILLIIALVGSQR
                     TARSILGM"
     gene            complement(10775..11017)
                     /locus_tag="VVR21_001404"
     CDS             complement(10775..11017)
                     /locus_tag="VVR21_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055271.1"
                     /translation="MNQKLTGFVYGVDASPMFSQAMSLLQKGLIAVGAFLVVMGIINL
                     STNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQITI"
     gene            complement(11035..12816)
                     /locus_tag="VVR21_001405"
     CDS             complement(11035..12816)
                     /locus_tag="VVR21_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEU6055272.1"
                     /translation="MGLAFGYFCHRLTLLYDSLTNAPPMERFAYLLGEGLNQVFNPLW
                     LFSFTRKSLLAFILGVITMSLVYLYVSTGQKVYREGEEYGSARFGTSKEKRFFYSKNP
                     FNDTILTRDVRLTLLEKKKPQFDRNKNLIVIGGSGAGKTFRFVKPNLIQLNCSNIVVD
                     PKDHLAEKTGKLFLENGYQVKVLDLVNMTNSDGFNPFRYVETENDLNRMLTVYFNNTK
                     GNGSRSDPFWDEASMTLVRAIASYLVDFYNPTGSSKQEQEARRKRGRYPAFSEIGKLI
                     KLLSKGDNQDKSVLEVLFEDYAKKYGHENFTMRNWADFQNYKDKTLDSVIAVTTAKFA
                     LFNIQSVIDLTQRDTMDLKTWGTQKTMVYLVIPDNDTTFRFLSALFFSTVFSTLTRQA
                     DVDFKGQLPIHVRSYLDEFANVGEIPDFAEQTSTVRSRNMSLVPILQNIAQLQGLYKE
                     KEAWKTILGNCDSLLYLGGNDEETFKFMSGLLGKQTIDVRSTSRSFGQTGSSSTSHQK
                     IARDLMTADEVGNMKRDECLVRIAGVLVFRTKKYFPLKHKNWKWLADKESDERWWHYH
                     INPLITEEEIDLSGHTIRDLSTEMSIY"
     gene            complement(12852..13340)
                     /locus_tag="VVR21_001406"
     CDS             complement(12852..13340)
                     /locus_tag="VVR21_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055273.1"
                     /translation="MSSEQQERQAMQYVERSSLFTVRTLLKLLEWSARQALAQDSAYK
                     IGVQKLEELLQSPYAIEAIDVSKDILDKPIDVEKFKELMESEKLPIAISWQKDYLYFY
                     AKDKTLLDHHLDELLKKLMSNPEKLEGLTFDKSLDQEIELAKEKIKVTEPSVVRTKEV
                     TL"
     gene            complement(13417..14001)
                     /locus_tag="VVR21_001407"
     CDS             complement(13417..14001)
                     /locus_tag="VVR21_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6055274.1"
                     /translation="MIRIVLFYLAIQLNGLLVSLYLHDYMTIKVLILLQTLLLGVACL
                     EITHHKTVQAKNITLQNRLRWLLLGFACMVSFAVLISFLFPVQTRNQSVLVEVGKQVP
                     HVIFLLFLVNASVLEEIVYRQLLWEKLTFPFVQIGVTSFLFSLAHGSNQLGSWLMYSC
                     LGVTLAVVRLKTDCMTAMTLHLLWNSLVYVLTFL"
     gene            complement(14004..14237)
                     /locus_tag="VVR21_001408"
     CDS             complement(14004..14237)
                     /locus_tag="VVR21_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU6055275.1"
                     /translation="MNERFWDNLEIILAEKELTWAELARKVFKGQYVYPSEFNRLYQK
                     LRHYKSNRLMPQTRWVERIVLVLDIDYEDLFKR"
     gene            complement(14246..14629)
                     /locus_tag="VVR21_001409"
     CDS             complement(14246..14629)
                     /locus_tag="VVR21_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055276.1"
                     /translation="MLEVYLGNNDNTNRDLLTILTTYGVTYRCTKACDVNREIILSLF
                     AKTMDCFELLSPRFLRFKRQYTISLNEMIQLILQKPDQNLRLPLIVCQNHVYPAIGLD
                     EVRTFLPRQVKEELFQASLMTQVTG"
     gene            complement(14640..15068)
                     /locus_tag="VVR21_001410"
     CDS             complement(14640..15068)
                     /locus_tag="VVR21_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055277.1"
                     /translation="MNLLHKKSILECTELEERIHQVEINQLLQKILSLPNFDCDFEVT
                     FEDDYHKEMNDPLFYESNLHRISDFLETRDIKNGVDTLLTKDNHLAFRAFGQNYTARG
                     KDGILTTLVTVKCSGEGRMPVDMSHYFSTPEPTVENSLTL"
     gene            complement(15052..16407)
                     /gene="dcm"
                     /locus_tag="VVR21_001411"
     CDS             complement(15052..16407)
                     /gene="dcm"
                     /locus_tag="VVR21_001411"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEU6055278.1"
                     /translation="MKFLDLFAGIGGFRLGMEAQGHECLGFCEIDKFARTSYKAMFKT
                     EEEIEYHDIKEVTDHDIRQFRGQVDVICGGFPCQAFSLAGRRLGFEDTRGTLFFEIVR
                     CAKQIQPRFLFLENVKGLLNHDEGRTFATILSTLDELGYDVEWQVLNSKDFQVPQNRE
                     RVFIIGHSRRYRSRFLFPLRRENSPAHLERLGNINPSKRGLNGEVYLTTGLAPTLTRG
                     KGEGAKIAIPVLTPDRLEKRQHGRRFKDNQDPMFTLTSQDRHGVVVAGNLPTSFDQTG
                     RVFDIAGLSPTLTTMQGGDKVPKILLREELPFLKIKEATKRGYAKATLGDSVNLAYPD
                     STKRRGRVGKGISNTLTTSDNMGVVVAAMEYRQDKWYEVTGIVLDGKLYRLRIRRLTP
                     RECFRLQGFPDWAYERAESVSSKSQLYKQAGNSVTVTVIEAIAREFRRMEEEEKHEPT
                     T"
     gene            complement(16565..17374)
                     /locus_tag="VVR21_001412"
     CDS             complement(16565..17374)
                     /locus_tag="VVR21_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU6055279.1"
                     /translation="MKRITANQYQTSERYYKLPKILFESERYKDMKLEVKVAYAVLKD
                     RLELSLSKGWIDEDGAIYLIYSNSNLMALLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHESIPVLDSDGASVKKTLGGAQKKTGPVLNSAPSETEGNETEY
                     SETEGSDFLIEDEEERQLVDDKQEENFSSKVDAVTKYDRDYIWDLVHDQLRQTGLSQS
                     ASDYAMIYFSERYQYALEHMRFARSAEVIAEYVFNGVLSEWTKQLRRQEVR"
     gene            complement(17371..17544)
                     /locus_tag="VVR21_001413"
     CDS             complement(17371..17544)
                     /locus_tag="VVR21_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055280.1"
                     /translation="MQKYEQSSRQLVMCQLMAIMGVDIVKATQLIDEMEQVGLIQFDE
                     FGNVGILVLEGQS"
     gene            complement(17622..19556)
                     /locus_tag="VVR21_001414"
     CDS             complement(17622..19556)
                     /locus_tag="VVR21_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU6055281.1"
                     /translation="MKKEVKVIKGDTTLKRTASGCVERSIKRVAAYCRVSTDTEDQIN
                     SYNSQVEHYTEFIQKNNEWTLAGIYADEAITGTQVDRRIDFQRLINDCMNGDIDMIIT
                     KSISRFARNTLDTLKYVRKLKEFNVAVFFEEENINTLTMDGELLLTILSSVAQQEVEN
                     ISANVKKGLRMKMERGEMVGFQGCLGYDYDPETKSISINEKEAEIVRYIFRRYIEGVG
                     GMVISRELEEQGYLSPRGNKRWTETTVLGIIKNEKYKGDLMMGKTYTVDPISKRRLDN
                     FGEQDKFYIENHHEPIISEEDFEKAQGIRLRRSKNRNTVANNGGKREKYSRKYAFSSM
                     LECGFCGHNLSRRNWHSSSEYTKVIWQCVNATKNGKKYCPHSKGIEEEAIEKAFMESY
                     RQVCHNNVEITNEFLKTVEEELKDNSLAKDLKKITNQLDKILKKEKDLVELRLNESIS
                     MDIYQDKYNEIAISKEKLLAEKRTLEVTLTDEKALKKRLEGFKKLLESNKYLEEFDRA
                     VFESIVDKIIIGGTNDEGEIDPAMITIIYKTGKKDSQDGRLFKSRRKNAKEVNEKADS
                     KLYPQSSDEVNNLCSYPMDNTRGVRSIATTKKRVKILYFKHFFKHFVFIEKSDFDIKK
                     VQKKYIDVNVCLDVDCVDKK"
     gene            complement(20221..20631)
                     /locus_tag="VVR21_001415"
     CDS             complement(20221..20631)
                     /locus_tag="VVR21_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6055282.1"
                     /translation="MPKEYYLYVNGQRVKVSEQIYKVYWREREHEKYLEQVDRKNHLL
                     FFSSLDHDGHFVDNIVDESVDVEKIVETQMMIEAVRNAISRLNAEERDIIERLYFNDE
                     TVRSVAKLKSITHPALIKRRNKILEKLKKFIEEL"
     gene            complement(20975..22333)
                     /locus_tag="VVR21_001416"
     CDS             complement(20975..22333)
                     /locus_tag="VVR21_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6055283.1"
                     /translation="MGKQDMKTQLLTKSPKDLLFQLAIPGIIGMVVIGLYPFMDGIFA
                     GWIIGDYAMSAISISMSLTIINGGISALIGVGSASILSRAIGKGDKETTDKIFGNFCY
                     WVILFSIVITVLGLVFAPNFLDLVGAKGNIKELGVRYLRVVFFGSIFVNFAQAGNMTM
                     RGEGALKQSMMIMGVGALLNIILDPIFMKLMGEYAIEGAAIATVISQIVQAILTFHYF
                     SKKSAFVGIHKIQKSKAIYSEMFSIGSSAMMMQILFAVQQTFLFKQAFAYGGDNWGIL
                     MSATMRLYMFSFIPLWGMSQGLQPVIGANFGAKQYQRVKDTMKIFMYGATILAAISWI
                     PSMFFSEKLLSLFNVRSEIIEAGVMNFKLFYSTFILYGIMIMTLTFFQSIGDGKKASM
                     IVMLRQLILFIPAILLLPKVFGGLAVWWAEPIVDFSMILLGLFLMLSRLRKIGKEEAI
                     NC"
     gene            complement(22369..24102)
                     /locus_tag="VVR21_001417"
     CDS             complement(22369..24102)
                     /locus_tag="VVR21_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055284.1"
                     /translation="MLSALKKILDFSGDEKKNIYHSIWVSFLFAIFHMLQISAIYFIV
                     KAVSEKDMSMTPAWIALILLVVSIVGRSIANYYSQLQQCHASYFMVANKRISIGEMFK
                     KIPMGFFNGNNGGEVVGISTTVLEDVENTAAMVMVNTLSGFINTIIFTLMILIFEWRI
                     GFIVTVGSLLYLVILSKMEKKSREVLPKRQMASAKLVDTVLEQIGGMSVIKSFNLTGK
                     GDEKVRGAIENTRKTNLDCEKLFTPYTIVQNILLDLFSILIIGAGIFFYQRGELSFLN
                     TVMTIIISFLAFSQIKLAGSATTALRVVSGSIEQTKKLEEFPQMDIEGKDIKPANFNI
                     SFENVEFAYSGKKILDDISVDIPQNQMTAIVGPSGAGKTTFCNLIARFWDIDNGKISI
                     GGHNIKEYSLESLMKQISMVFQNVYLFQDTIENNIKFAKPNATHEEVVDAAKKACCHD
                     FIMNLPEQYQTVIGEGGASLSGGEKQRISIARAMIKNAPIIIFDEATANVDPENEDKL
                     QLAMEELTRNKTVIMIAHRLKTIKNANQILVLANGKIMQKGTHEELIQTDGIYRNFVE
                     ARQVATKWQLS"
     gene            complement(24096..>24906)
                     /locus_tag="VVR21_001418"
     CDS             complement(24096..>24906)
                     /locus_tag="VVR21_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055285.1"
                     /translation="INSILEGKEQIHSNVDVKINKYDIALQDVKFGYEEGKEILHGVS
                     LNIEEGTTIAFVGPSGSGKSTLAKLIAGYWDINTGSIKIGGYNLQEIPLKQLYSLVAF
                     VSQDNFLFNESIRENIRMGNPSASDKEVENIAKKSGCHDFIMNMEKGYDTVVGSSGSH
                     ISGGERQRISIARAMLKKSPIVILDEATSYIDPENEVIIKEALSKLIQNKTVIVIAHR
                     LSTITDVQQIFFVENGELISHGKHNELMEDCELYKKMWNAHIGVKDGEIKC"
BASE COUNT         7295 a         5309 c         4134 g         8168 t
ORIGIN      
        1 gaacaagtct agtataattt taccacaaag taacatgatt tgcaagcgat ttcaataata
       61 aagatatatg attatcctca ggaataaata aatttgaaag ttctataatg aagttagcca
      121 ccttacctta gtcaagaatt agatgtttca ctatgtttga gtaagttgat gatttcattt
      181 gataacaggt ttgaaactgt taggctaggt ggccaaggct aatcatagcc ttggtttagc
      241 tgaaaaaaca ggttcaaggg ttcctgttgt caaatgaaat gtgatttaag gtataagaaa
      301 acacctctgt gctatacttg ttgttcacca caaacacaag gaaaggcaca gagatgcaag
      361 aacattatac cccaaaaggg aaacatttga caatagataa ccgtcgcttg attaagcggt
      421 ggaagaatga aaataagtcc aatcgtgaaa ttgcaggctt gttaggaaag gcgcctcaaa
      481 cgattcataa tgaagtcaaa agaggtacaa ctttacaaca agtgagaaaa gggctataca
      541 aaaaggtcta ttctgccgat tacgcacaaa ctgtttacca attcaatcga aaacggtcgg
      601 tgaaaaagtt aattttaaca aaggaaatca gagagaagat cttacactat cataagcaaa
      661 aattttcgcc tgaaatgatg gttaacaaga agcaagtgaa agttggtatt tcaaccatct
      721 actactggtt tcataatggt catttaggat tgacgaaggc cgacatgctt tatcccagaa
      781 aaaggaaagg tgtcaagaag caagctagtc cgaactttaa gccggcaggt aaatctatcg
      841 aagaacgtcc tgacgttatt aatcttcgct tggaaaatgg tcattatgaa attgataccg
      901 tcctactgac taagataaaa aattattgcc tgttagtctt aaccgaccgg cggagcagac
      961 accaaattat aaggttaatt ccaaataaaa ctgctgaatc tgtcaatcag gcgcttacgt
     1021 tactattagg ggagcatcgt attctgtcca ttactgcaga taatggttcg gagttcaaac
     1081 gattgtctga ggtatttcct gaggaacata tctactacgc acatgcttac tcttcatggg
     1141 agagaggttc aaatgaaaat cataatcgat taattcgggg atggttacct aaaggaacca
     1201 agaaaacgac tccgaaagaa gtagctttta tcgaaaattg gattaacaac taccctaaaa
     1261 aatgcttgga ctacaagtcg ccaagtgaat ttcttttggg tggctaactt caacttgaaa
     1321 tttgggcttt gtctctatgc taaaggaatc cgctataaat acaagtacta tagccgtcgg
     1381 cattcctcat taacacgacc caatttgatt aatcagtgtt ttcaaacaaa aggtaaaaat
     1441 gaaatctggc tgggggattt aacttatatt ccgacaaaag caggtactct ttatttatca
     1501 ttatatatat gtttatagca gaaaaattgt tggttaggca atgggaaatc gaatgcaaga
     1561 taagttggta acgaatgttt tcaatcaagc ttatcataga gaaaatctca aataagaact
     1621 agtcggccat accgatcaag gatctcaata tactggagct agatttcaag aactccttaa
     1681 acagaaaaga tgcaagtcta gcctgagtcg aaaaggcaat ccatatgata atgcacccat
     1741 ggaatccttt tacaaaacat aaaaagagaa cttgtcaatg atgccaattt cgcaactatt
     1801 gaacgaaatc tttaaatata ttgaaatcta ttacaatcct aaatatctcc attcggcatt
     1861 agggtaccaa taactaatag agtttgaaaa aaatagtcac taatcatcga gtccactgaa
     1921 aaagtaagct ctacagttca actaaaatga aaaaagaggg atctatctcc tgcttggata
     1981 gattcctctt tgcttttcct tatttttggt ttattagagt tataatcctc ttcatattaa
     2041 ccacaaatat ggttgtggcg gcttgtaact ccatgtttaa aagacctggt gctctagcta
     2101 cattaagacc atgtctgttt tcaagttccg catttttggc ttctatcttg tagcgatgtt
     2161 tggccttttc tttaaaatag ggcgcttcct gaaacctctt ctggaaaata tgttcatcgc
     2221 tcttaagggg tatcaaataa gtcttagact tagccccttc tttataacag cccacttttg
     2281 aagggcatat ttgacagtgc ttgatgtcaa aatagtgggt ttcctgagcc gtccttcttc
     2341 ctgtctttgc cttctttagt gccatatgcc cttctggaca aacaaagaga cctgcgtcct
     2401 tgttatagaa aaactcatct tccttcctac gaaagccttt tgaaatagtt ggatatggcc
     2461 tagcgactca atgcacacgt tctttcttgg taaattgcat attatccttc ccagagtagg
     2521 ccctatctcc aacaatagct tcaatcgtca cgccattatc cttagatttg tgatagagtt
     2581 cttctaaaac aggaccatca cttttttcac ccgatgtcac cacacaggca gtaataatcc
     2641 gttcatcggt catggcaaaa tgctctttgt acccgtaaaa ggaactatcg gctgacttat
     2701 gtccaattct tgcttcttct ttgacagagg attccaagtg ctctaagtca tcctctacag
     2761 cttctttaag gtaattgaat tttgtgagat agctggtatt ccagtcaatt cgtcatgctt
     2821 ctcaaggact gatattaatt cttgtgtata tcttaattca gctactagag tatcttcctg
     2881 aggcttacta ggaaattctg ccttgatata ttccgaatac tgataaatcg ttttacgcaa
     2941 ggcttttgag cgttctcgga ggacttcttg aggtttcttg tgattgtaat gaactttggt
     3001 atgagtcgca tccacaatga gaatgttact tttaatcaga ccgagctcta tcgcaatctg
     3061 aacagattta gcgatgagca aatcaagtaa tcgttcatct ttgttccgaa gttttcggaa
     3121 tttagtcaat gaggacggtt caataacagg agctagacca aggaagtatt tgaaggtcat
     3181 accagaaaag gagcgctcca ccacatccac atcggacaac ttatagatgt cttttaataa
     3241 gagatacttg aacatcatga taaggagaga ggttggatat tcaaaaagta ctgtttgtgg
     3301 gtcattttca tcaacactaa tttgaaaatc atcttcaatt aaattcgcaa aatctatcct
     3361 catctgcgga attaatgcat tcacaagaaa gtcttctgct tttaaatttg attccttatt
     3421 gaacttatct tgttgcgtat tagaacgaga ttgccatggt tcgtctttac catatccaat
     3481 tacctgccaa tccaagatta aatcaatatc ttctgaaaat cgcttaatta aatcatagca
     3541 cttagaaaga cttgtgcccc ctttaaatgt aaatgcatcc ttccattcac tctttgtaaa
     3601 gagatagttg agtacaaaac aaacccaata gtctttctca acaatcactt cattgatacc
     3661 aagtctttcc gaagcatttc taataatggc ttgaaggtct tctttggaaa tttttttaaa
     3721 ttctagcatc tttaggattc tcctattttt ttcaagactt tataaatcca ggcactggta
     3781 gccttgcctt cctcaagaag tttttcttta tcacttatag ttaacctatt cttaagatat
     3841 aaaatctgtt cttctgaaat attatctttt ccaatagctt tgatggcttg aataactagc
     3901 gcagttaatt gcgacatatt tgaaatggta ctatttgttg ttcgcttgaa cacaagtttc
     3961 gtatttccaa ttataaaatt tacataccgt ccatcagaaa tataagtcca ttgagctgga
     4021 acttgtgtcg acaaccctaa taaatttaga gctgtgttac ctgaaggtgc aattgtccaa
     4081 ttatattttc tagcaatggc aatagccact tcatttattg aaggagactc atattctcca
     4141 atcaactcaa taaaccttgg tttgtaatat acaccgttta caattcgttg aatcgttcct
     4201 tcgttaacaa atcgattcaa gttttttcta atggtctcat aatcagcaag ctctagaaaa
     4261 tcatttgaaa taaagactgc gccatctggt agattatcaa tcttactatt tattttagct
     4321 tttatgttac tcaattcctc accaccttgt cccaaatatt atacaacatt tgggacaaaa
     4381 tgacaactat ctttctgtct attatttcgt cgtatacgca aaactcaagc tgctatccac
     4441 tccagataat ttacggaagg tatagttggg attgccattg taattggttt cggagataag
     4501 gaatgagcca tctgggtaaa ctttctcgat aaaagccaca tgtccgtatt ctgtcggtgt
     4561 gccatgtcct cctcccgcaa aagagagaat agctcctgct tgtggaattg tgcctgtttc
     4621 accaccaagg cttgcggctg tacgcaccca atcctggcca ttacccatgg tactgataat
     4681 cggaatcttc tcaccatttt tacctttgag ttttaaaccc agttggttga tacgggctgc
     4741 gactccccaa gtacattggc cgtaagcata acccataccg tcaccacctc ttggaataga
     4801 gttctcaaag aggtctccac gtacagcttc aagagatttt ggatcgcttt gtgccgtccc
     4861 accatttggc tggctaaagc ctttttcaat ttgatagaac cactcggtcg ctcttgtttg
     4921 tcgctctatg agtttatctc ctgaattgcc ttcccagtaa atcagaaaga gttgggcaag
     4981 actggctgga ctacctgaat ttttgaagaa gtcctttaac caattggaat aataaggact
     5041 atccccatgc aacatgaagt ccagttgtaa ccccaaatca taccactttt gatgttttcc
     5101 tttggcatat tccagcaaca aggtatgtct gcgtgaccca tctgcggtat ccgtccattg
     5161 tcctaagccc aaaccacgtt tgagaatatt tgggtaacgt ccattgtata tagttggacc
     5221 attaagtgag agccatccct catcatccca cgagctgtct gtcgcaccaa tagggggaga
     5281 tagatagtcg ccctccgcac gttttggatt aattgaggat tctaccgacc aatttcctaa
     5341 gatagctgcg atagcttgat tggtcgcacc ctcacttttg agatagtcat aaatcgcctt
     5401 ggctctctca aactcatcac caccaaactg accgatagtt ggaagaatgg tggtctgaac
     5461 ctggatcact tttggaaagt agaaagctgg attaacatag accaacttat ccgtgtcatc
     5521 atcaaccttc tgataggtga cttttaggcc cgttccatcc ttgttttgac caataatgtc
     5581 tcctgccaag acttgttgat tttcacttac tctacctgaa tgaatgccaa acaaggttag
     5641 tttagtccta ttcactccct taccagatgt cagaataacg ttctctccat caagagatac
     5701 cttaccatcc atcggagcca caatgacttg gtcttctttt gcttctaaga taatatggtg
     5761 atgaagtgtt ggtttctcat caatgacctc ataaccatat cggtaggaca tgtttaagct
     5821 atcctcatcc gtctgtccct gaaagggatt gtccaattct tgaagggcta aatagttgcc
     5881 ttcttcggtc aactccttta gttcttcctg gtcctcatca gacagcttgt agctaggttc
     5941 tttatacagg tcagacatgg atttaataga atcaccacca tttaagtctg tccacacttg
     6001 actgagaaat gctttgtaaa tcgcaccacc tgtttcctta acatcatcta acttgtaatc
     6061 ttgatattga tgattcatat agaccataac gtcatcaacc ttggtgtaat aggtaatccc
     6121 tttttcgttg gttcttgtat gctccgcatc ttcccacgtc atgtgggtat aggccttggt
     6181 caactccatc tcatcttgtt gaatgacact gcttcctgaa acactcatga aaaagctcat
     6241 catcaaaagg agtatcaaga gaatgcctga gacaatccaa gtcaaaggat ttcccgcaat
     6301 tgcagaaaag aaggtcagac ttcctttaat ggcttgggca atccccttaa ttcctgctag
     6361 actgtgcttt ctggcatgct ttaaaaaggt ttggtagcgt cttcttgatt taagcggttt
     6421 ctggcgtgtg aatccttttc cctttttgaa gttgtggaat cgttcctttc catgagcgac
     6481 tttggtcttt gtaaaacgca cactagtctg tccacttttc accgccactt taccagcttg
     6541 ataggtaaat ctgccatagc gtctggcttt caaactagta tcctttatgg ttcttagacc
     6601 atctagatca tcatcctgtg ctaccaggtc aagcgattca gatatagcta agcctaatcc
     6661 acctttaacc ttggtagagt ttttcttaga ctttcggact ttcttgagtt gtttgacctc
     6721 acgtttggca gacctcactt ctttttcagc acttagtcga tcaaatgatt tttcttggtg
     6781 aaattgaaaa tgagacttcg aggaagggtt ttctttttgg aagagaaact tgggattgac
     6841 cgccttttgt ttctcatcta gcttcacttc tgacaattgt ttttttgccg tccgcaaacg
     6901 ctcttgggct tggggaagtc gataattctt aatttccttt acccttaaca gtctaggaga
     6961 cacataggta atttccttta gaaacttctc ttctgcttcc ttttggctac ctagcaaatt
     7021 ttgttttaac tctgttttct tatcttgaaa cagagaattt tgggctggtt ttcgaaatcg
     7081 tcctttttta ggaacagtct gttttaaggt cctaacttct ttccgataat gcatacgagc
     7141 tgattttaag ttgcttcgaa agttttgcct agcttgtttg actagctttt tatcctcttt
     7201 catctcatgt cctcattttt tcagggtctg tactcatgat gtcaaagagc ttggtgtgtt
     7261 gtggaatctt attcttaaac gggacaacgg tggaaccggc cttgattagg ccagcacctt
     7321 tttcaggatt gaccaagtat ttctctagtt ccttggaaag tccaagcaaa tgcaccaact
     7381 cttcgcgatc gctcttagcc tgttttaata gaatcatgaa ctcgctattg gcaataatac
     7441 gtctgccatt ggcatccaaa agaagtgtct ccacattctg agtaatgcca gttggtatcg
     7501 ccccatactt acggacacga ctccagagtt taaagaagaa atcagaggca tatttgtcca
     7561 ataagagaag ctgcatttca tcaaagtaaa tccaggtctt cttccctagt ttttggtttt
     7621 tcaccacacg attccaaatc tggtcaaaga taaccatgag ggcaatttgt tttaattcat
     7681 cgcctagctt tttgacattg taaatcagaa aatgactatc tgtcttgata ttggtccgat
     7741 gcgagaaaat atctagcgat ccttccacat agagttccat atacagtgcc aagttcttag
     7801 cttcctgttc aggttgttga gataagacaa agacccattc gaccaaagat ggtgtatcaa
     7861 aatgcttata ggtaagtcgt gtcacacggt caatcagcga cttttcgcga ccatccattt
     7921 tgcggtccaa gagctttcca atccaagaca agaggaattc ggatttaacc ttgactggat
     7981 cctcatccat attctcatcg gatagttcta aaacatttaa gaaggtagtg gaatctggtg
     8041 caatatcaat actttctcca ccaaaggctt gaccgataat gctgtactca ttttctgggt
     8101 caacaataat aatttcggta tcgctatctg cttccttgag cttagtagag atgatttcat
     8161 gttttgtcgc catccctttt ccagctccag aagtccctaa aatcaaacct gacggagtat
     8221 ttaacttgcc acggtcaata ctgatgatat tacttgagat ttgattgatg ccataaaatt
     8281 tcccaccctt gtcctgaata tcaacggaag tccaaggtgc attcacggca atgtttgaag
     8341 tcaatagaga acgagaaact ccttcgagat agttcttccc aaatggcaag agactattaa
     8401 aagcagcttc ttgcatgtag gtcaagttgt caataatcat atcatttgac cccgccactt
     8461 gcttgataat atcaagggct tgtttgagtt ggtcttcagt atccgccagc acgccaatta
     8521 gaaatacggt gtcaaacagt ttatctcctg tttgggtcat ggtttgaaga agagcttctg
     8581 cttcatcgat attgttttca agaacatggc cgaccttctc caaatagatg ccagtccgag
     8641 ccatcttttg ttgttcccca atcttttgcg attccatcaa ggttttcttg gttcgtaact
     8701 tagtcatagc ttcagactta gttgagcctt tggcgtgtag gctaatcatc acttccaaat
     8761 ctatccccta gctccatacc gtaatcacga acatagacaa tctgtaataa tctatcgtcc
     8821 aattcaatat gattcttgtg tttaaaggaa aggtaggttg gcgcaataaa gtgtttggtg
     8881 gattgacctg acagggttaa atccttgtaa gagaatggta aatgattttc acctcgtaac
     8941 atatccgcaa ggacattcac tcgctcctct ccatcaagta aaccaagaga tacatcaatc
     9001 tctgaaaagc cactcttgaa atattcccca atctgtgaca gggaacgaaa agctagtttt
     9061 ggtgtttggt cgctcttgcc aaatgaaagc aacttgacag ctgaaaagtt attctcaccc
     9121 gcttctaagt tggcatccat catgcgattc aattcatcac ggtagccatc aaacccatct
     9181 tcctgtaagg gatagagaat actcttacga aatttttcca gattgacttt ttgattgaaa
     9241 atagtcagtt ggaaattggt cttatcgtcc agtgaattga ttaaatcaga atatttctcc
     9301 acaatagctc ccttatcgtc taagccaact gtttggtaat tgacatctcc taagagatag
     9361 gtttgtgaaa aatggcttgg gctgacctgc atgagtccat tttgaaagag accttgatag
     9421 gctaacgtat ttagggtaga aggtctgatc tcctgcttct gtgttttcgt cttttgctta
     9481 ttgtcattag aagaggtctt ttgtttcatt aagtggttta attttttcac gttggtctcc
     9541 ttttcttcca gtaaatgtgc ggtctggcac cgttagttca taatgaaaac gatacttgag
     9601 ataggtttca aatggtaaat cattgggtcg atagacccca aataacatga gtggaatggt
     9661 aaagctaaaa acaaaaccat agacaaacca atccccaaat tgccagtaaa ataggttcaa
     9721 gcccaatacc ataatagtta ttgcaacggc tggaaataca aaaacaacct gtcttgtggt
     9781 aaatcccaac catgcacggt gttgaacctt agaaatgtcc ttaaagacac gagtgttcat
     9841 aaatgttctc caatctagat aagctataaa aagaggaggc gggcaattta ctcccatcct
     9901 cctacatccc caaaatactt cgggcggttc gttgactgcc aactaaggca atgattaaca
     9961 agatggcctg taccaaacca ccaaacataa tggcgagtga ttccatgact ccagctccat
    10021 ttgatacggc aatctttcca gcagattcaa acaagggaac aagagataca atcagaaaaa
    10081 tcaaaattcc ttgtacggca tagaccataa tgtttttgag gtagccaatc ccaacacttc
    10141 tccagtcatc actaaggaag gtcggaatgg taacaggggc aaaaggaatc attagataga
    10201 gttggataaa gcgaatggta atcaagatat tgacaaccat gatactaacc attcgcacca
    10261 accaaatgag aatcgcaaaa aagccaataa tcatttttcc tacaattcca gaacccttga
    10321 tgcctgagat agtatcgtaa ctagcaccac catttgtgac aagccctgcc acttgttcaa
    10381 taacataaga ggcaagggca ataatggctt ccacaataac cgtcgtattg gtaatcacga
    10441 ccgcgaccat aatgtagctg acaatcatag gtgctatggc ttcaaaggtc atcgcaccac
    10501 ctgagttggc gattttcttg gccatttttg agaattcgag tacgagaaca accgcaagaa
    10561 tagctactcc caagggctgc ataatcccct tggtaatggc tgtcatgtaa gaccacactg
    10621 tcggattaaa gtccgctagt gacttaacca agttggcagt tgtttctaaa tcaacttgaa
    10681 acccttcaaa aaggctatcg ctagatactt tttcagaggc tagaaataca aaaggtgacg
    10741 taaaattcat catcatgtca tgtgctgtcc tcctctatat ggtaatctgt gtcacaaaag
    10801 caccagcggc acctaccatg acaccaccaa caatttctaa aatggcattt cggacacctg
    10861 gtccaccatc tttaatgttg gttgacaggt tgataatgcc cataacaaca agaaaggccc
    10921 ctactgcaat taagcctttt tgtaatagag acatagcttg ggagaacatg gggctggcgt
    10981 ccactccgta aacaaagcct gttagttttt gattcatatt tttcctcatt tctattaata
    11041 tattgacatt tctgtgctta aatcccttat tgtatggcct gacaaatcta tctcttcctc
    11101 agtgattagg ggattgatgt ggtagtgcca ccagcgttca tcagattcct tatctgcaag
    11161 ccatttccaa ttcttatgtt tgagcggaaa atatttcttg gttcgaaaga caagcactcc
    11221 tgcaattcgt acgaggcatt catctcgttt catattccct acttcatctg ccgtcattaa
    11281 gtcacgggca attttctggt gagaggtgga acttgagccc gtctgaccaa atgaacgact
    11341 ggtacttctg acatcgatag tttgtttgcc tagaagtcca ctcatgaact taaaggtttc
    11401 ctcatcattc ccacccaaat ataagagact gtcgcagttc cctaatatgg ttttccaagc
    11461 ctctttttcc ttatacagtc cttggagttg ggcaatattt tgcaagattg gtactagact
    11521 catattccta gagcgaactg ttgaggtttg ttcagcaaag tctggaattt ctccgacatt
    11581 cgcaaactca tccagatagc ttcgaacatg aatcggcaat tgccctttaa agtccacatc
    11641 agcctgtctg gtcaaagtag agaaaaccgt agagaaaaat aaagcagata ggaaacgaaa
    11701 agtcgtatca ttgtctggaa ttacaagata gaccatggtc ttttgagtgc cccacgtttt
    11761 caaatccata gtgtctcttt gcgtcaaatc aatcactgat tggatattaa aaagggcaaa
    11821 tttagctgtt gtaaccgcaa tcaccgaatc caacgtctta tccttatagt tttggaaatc
    11881 cgcccaattt cgcatggtaa agttttcgtg gccatatttc ttagcatagt cttcaaacaa
    11941 gacttcaagg acacttttgt cctgattgtc tccctttgat aagagtttga tgagtttccc
    12001 aatctcagaa aaggctggat aacggccacg cttacgtctt gcttcctgct cttgcttgga
    12061 acttcctgta ggattgtaaa aatccaccaa ataagaggca atagctcgca ccaaggtcat
    12121 agaagcctca tcccaaaagg gatcactgcg agaaccattt cctttggtat tattaaaata
    12181 gaccgttaac atgcggttca aatcattttc agtttctaca tagcgaaagg gattaaaacc
    12241 atctgaattg gtcatattaa ccaagtctaa aaccttgact tgataaccgt tttctaaaaa
    12301 gagcttgcct gttttttcag ccaaatggtc cttaggatct accacaatat tggaacagtt
    12361 aagttggata aggttaggct tcacaaagcg aaaggtcttt cctgcaccag aacccccaat
    12421 gacaattaga tttttatttc ggtcaaactg gggtttcttc ttttccaaca aggttagacg
    12481 aacatcacga gtcaaaatcg tgtcattgaa aggattctta ctgtaaaaga atcgcttttc
    12541 cttactggtt ccaaagcgtg cagaaccgta ttcttcccct tctcgataga ccttctgtcc
    12601 tgtcgataca taaagataga ctagcgacat cgttataact ccaaggataa aggcaagaag
    12661 ggattttcga gtaaagctaa atagccataa aggattgaaa acctgattta acccctctcc
    12721 taagaggtag gcaaaacgtt ccataggtgg tgcattggtt aaactatcat agagtagggt
    12781 taggcggtga cagaaataac caaaggcaag tcccaagaat ccaaagacta atgcttttca
    12841 tctgaaatac attacaaggt aacctccttg gttctaacta ccgaaggttc tgtcactttt
    12901 attttctctt tggccaattc aatctcttgg tccaagcttt tatcaaaagt tagcccttct
    12961 aacttttctg gattagacat cagtttcttt aataattcat ctaagtgatg gtccagcaag
    13021 gtcttatctt tggcataaaa gtagagatag tctttttgcc aactaatagc aatcggtagt
    13081 ttttctgact ccatcaactc cttgaatttc tccacatcga ttggcttatc cagaatgtct
    13141 ttactgacat caatcgcttc aatggcgtaa gggctttgaa ggagttcttc cagtttttga
    13201 acaccaatct tataagctga atcttgggct aaggcttgcc tagccgacca ttctaagagc
    13261 tttaagaggg ttctaacagt aaataaacta cttctttcca cgtattgcat cgcttgacgt
    13321 tcttgttgtt cagatgacat gatgacttcc tcttctttga attccctatc aaacataagg
    13381 tgcttccata atacagaagc actcttgatt ttggtatcac aaaaaggtca agacataaac
    13441 caaactattc caaagtaaat gtaaggtcat tgccgtcata caatctgttt tcaaacgaac
    13501 aacagccaag gtcaccccaa gacagctata catgagccaa ctccctaact gatttgatcc
    13561 atgggctaaa gaaaagagaa aactggtcac tcctatttgt acaaaaggga atgtcaattt
    13621 ttcccacagc aattgcctat aaacaatctc ttcaaggaca cttgcattga ccagaaacaa
    13681 taaaaagata acatgtggaa cctgctttcc tacttcaact agtaccgatt gattcctagt
    13741 ctgaactgga aaaagaaaac taattaagac tgcaaaagaa accatacacg caaagccaag
    13801 aagcaaccat cttaggcgat tttgtaaggt aatatttttt gcttgaacag ttttgtgatg
    13861 agtaatctct agacaagcta cacctaaaag aagcgtttgt agcaggatta agaccttaat
    13921 cgtcatatag tcatgcaggt ataaactcac aagaagaccg ttaagctgta tggctagata
    13981 aaacaacact atccttatca ttgtcacctc ttgaataaat cttcataatc aatatctaag
    14041 actagaacga ttcgctcaac ccatcttgtc tgtggcatta aacgattgga tttgtaatgc
    14101 cgtaattttt gatagaggcg attaaactca cttggataaa catattgacc tttgaatact
    14161 ttgcgagcta gttctgccca agtgagttct ttttctgcca gaatgatttc taaattgtcc
    14221 caaaatcgtt cattcatctt cacacctacc ctgtcacttg tgtcatcagg ctggcctgaa
    14281 acagctcttc ttttacctgt ctgggaagaa aggttcgcac ttcatctaac ccaatagctg
    14341 gatagacatg attctggcag acaatgagag gcaaacgaag gttttggtct ggcttttgga
    14401 gaatgagctg gatcatctcg tttaaactga tggtgtattg acgcttaaag cgaagaaatc
    14461 gtggcgacag caactcaaaa caatccatgg ttttggcaaa gagtgacagt atgatttcac
    14521 ggtttacatc acatgctttt gtacaacggt aagtcacacc ataggtcgtc aaaatggtta
    14581 gtaagtctcg atttgtattg tcattatttc ctagatatac ctcaagcata ggctcctcct
    14641 tatagggtta ggctattttc aactgttggt tctggagttg agaaatagtg actcatatca
    14701 acgggcatcc gtccttcacc ggagcactta accgtcacca gagtcgttaa aataccatcc
    14761 tttcccctag cagtataatt ttgaccaaag gcacgaaagg ccaagtgatt gtctttcgtc
    14821 aatagtgtat ctactccatt tttaatatcc ctagtttcca aaaaatccga aatccgatga
    14881 agattggatt cgtagaatag gggatcattc atctctttgt ggtaatcatc ttcaaaagtc
    14941 acctcaaagt cacaatcaaa attggggagc gacaatatct tttggagtag ctgattgatt
    15001 tcaacttgat gaatacgttc ctctaattca gtacactcaa ggatactttt cttatgtagt
    15061 aggttcatgt ttttcttcct cttccattct tctaaattct cttgcaatgg cttcaataac
    15121 tgtgacagtc acactattac cagcctgttt gtatagttgg ctcttactag aaacactttc
    15181 tgctctttca taagcccaat caggaaaacc ttgaagtctg aaacactctc ttggtgtcag
    15241 tcgtctaatt ctcaggcgat agagttttcc gtctaagaca atccctgtga cttcatacca
    15301 cttatcctgt cgatattcca tagcagcaac tactactccc atattgtctg aagtcgtcag
    15361 agtattggat attcccttac ccactcgccc tctccgtttg gttgagtctg gatatgccag
    15421 attgacagag tctccaagag ttgcctttgc gtaccctctt tttgtggctt ccttgatttt
    15481 cagaaatggc aactcctctc tcagcaaaat ctttggcacc ttatctccac cctgcatggt
    15541 ggtcaaggtc ggtgacaaac cagctatgtc aaatactcta ccggtctggt caaagctagt
    15601 cggcagattt cctgcgacga caacaccatg tctatcttga ctagtcaaag taaacatagg
    15661 gtcttgatta tccttaaagc gacgcccatg ttggcgtttt tcaagtctat ctggtgttaa
    15721 gactggaatg gcgatttttg ccccctctcc tttacctctc gttagtgtag gagcaagtcc
    15781 agtcgtcaga tagacttcac cattcaaacc acgtttagag ggattgatat ttcctagcct
    15841 ttcaagatga gctgggctgt tttctcttct gagaggaaat aagaatctgg aacggtatct
    15901 tctagaatgt ccgataataa agacccgttc tctgttttgc gggacttgga agtccttact
    15961 gttaagcacc tgccattcga catcataccc caattcatcc agcgtggaga ggattgtggc
    16021 gaacgtccgt ccctcgtcgt gattgagtag gcctttgacg ttttccaaaa atagaaaacg
    16081 tggttggatt tgtttggcgc atctaacaat ttcaaaaaag agagtccctc gagtatcttc
    16141 aaatcccaat cgtcttcctg cgagtgaaaa agcttggcaa ggaaatcccc cgcagataac
    16201 atccacttgc cctctaaatt gtctaatgtc atggtctgtg acctctttaa tgtcatggta
    16261 ttctatttct tcttctgtct taaacatggc tttgtaggaa gttctagcga atttatcaat
    16321 ttcacaaaag cccaagcact catggccctg tgcttccatt cccagcctaa aaccgcctat
    16381 cccagcaaat aaatctaaaa atttcatttt tcctctcttt ccaaataaaa aagagcctta
    16441 cacttgtaaa actcttgcct atatatgatc atccatttct ggtgcacgga tgatttcaac
    16501 gatcaaaatg atgagcgaaa tcagatagat cccacctagt atccaccaaa tcatcttaat
    16561 cacctcacct tacttcttgt cgtctcagtt gcttggtcca ctctgacagc acaccattaa
    16621 acacgtattc agctatcact tccgctgacc gagcaaatct catatgttcc aatgcgtact
    16681 gataacgttc actaaaatag atcatggcat agtcactagc cgactgtgat agacctgtct
    16741 gtcttaactg gtcatgaacc aaatcccaga tatagtctcg atcgtacttt gtcacggcat
    16801 cgacttttga agaaaagttt tcttcttgtt tgtcatctac tagctgcctc tcctcctcgt
    16861 cctcaataag gaaatcactc ccttcagttt cactatattc agtctcattt ccttcagtct
    16921 cactaggggc tgaatttaag actggccccg tctttttttg agccccccct agtgtttttt
    16981 taacactagc cccgtctgaa tctaagactg ggatagattc atgttctaat tcccccaagt
    17041 aaattttatt tgccattcga cctttttcac tagaggactg ttggacttca tcaattaagc
    17101 catattcacg taaggttttc ttgatagaga gtaattttga ctttgaacag cctaaaagtg
    17161 ccatcagatt tgaattggaa taaatcaagt aaattgcccc atcttcatca atccaacctt
    17221 tactcaaaga caactccaaa cgatctttta aaaccgcgta ggctacctta acctccagtt
    17281 tcatatcctt ataccgttca ctctcaaaca aaattttagg gagtttataa taacgctctg
    17341 atgtctgata ttgatttgcg gttatacgtt tcatgattgt ccctccaaga ctaatattcc
    17401 aacatttcca aattcatcaa attggattaa tcctacttgt tccatttcat caatgagctg
    17461 agttgctttt acaatatcaa ctcccatgat agccatgagc tgacacatca cgagttgacg
    17521 tgatgattgt tcatactttt gcatcatttc ctcctgaaaa taaaaaaagc gagaacactt
    17581 ataaaaatgt tctcgctgaa ccaatatatt ttctgacgta tctatttttt gtctacgcag
    17641 tcgacatcca aacaaacgtt cacatcaatg tacttttttt gaaccttttt tatgtcaaaa
    17701 tcactctttt caataaagac aaaatgcttg aaaaagtgct taaaataaag gatttttaca
    17761 cgtttcttcg ttgtagcaat actacgcact ccacgtgtgt tgtccatagg ataggaacac
    17821 aaattattaa cctcgtcgct tgattgagga tacaatttac tgtcagcttt ctcattgact
    17881 tccttagcat tttttcttct gctcttaaat aatctcccgt cctgagaatc ttttttcccg
    17941 gtcttgtata tgatagtaat cattgcagga tcaatttcgc cttcatcgtt agttccacca
    18001 atgatgattt tatccactat actttcaaat acagctctat caaattcctc aagatattta
    18061 ttggattcaa gtaatttttt aaatccctca agccttttct tcaatgcttt ttcatcggta
    18121 agtgttacct ctaaagtcct cttttctgca agtagtttct ctttactaat agctatttca
    18181 ttatacttgt cctgatatat atccatgctg attgactcat tcagtcttaa ctcaacaaga
    18241 tccttttctt tctttagtat cttatcaagt tgatttgtta tcttcttcag gtctttagct
    18301 aaactgttgt ctttcaattc ttcttccaca gttttaagga attcattggt aatttccaca
    18361 ttattatggc atacctgacg atagctttcc ataaatgctt tttctattgc ttcttcttca
    18421 atccctttac tatgtggaca atacttcttt ccgtttttag tggcattgac acactgccat
    18481 ataacttttg tatattctga actcgaatgc caatttcttc ttgaaagatt atgaccgcaa
    18541 aatccacatt caagcatact gctaaaagca tattttcttg aatacttttc tcttttacca
    18601 ccattattgg caacagtatt tctgtttttt gaccttctta atctaatacc ttgagctttt
    18661 tcaaaatctt cttctgaaat gattggctcg tgatggtttt ctatataaaa cttatcctgt
    18721 tctccgaaat tatccaatct tctctttgaa ataggatcaa ccgtataggt ctttcccatc
    18781 ataagatccc ctttatattt ttcgtttttt atgattccta aaacagttgt ttcagtccat
    18841 cttttatttc ctcttggcga taaatatcct tgttcttcca gttctctgga aattaccata
    18901 ccgccaacac cttcaatgta tcttctaaaa atatatctta caatctcagc ttctttttca
    18961 ttgatagaaa tgcttttagt ttccggatca tagtcatagc ctaaacaccc ttgaaagccg
    19021 accatttctc ctctttccat cttcattctc aaaccttttt tgacattggc tgaaatgttc
    19081 tctacttcct gttgagcaac tgaacttaaa attgttaaaa gcaactcacc gtccattgtt
    19141 aaggtgttta tgttttcttc ttcaaaaaaa actgcaacat taaattcttt cagctttctt
    19201 acatacttta aggtatctaa tgtatttctc gcaaatcttg atatagactt tgtaattatc
    19261 atatctatat cgccattcat acagtcattt atcaaccttt gaaagtcaat tcttcgatca
    19321 acctgtgttc ctgttatcgc ttcgtcagca tatattccgg caagagtcca ctcgttattc
    19381 ttctgtataa attctgtgta gtgttctacc tgagaattat agctgttaat ctgatcttcg
    19441 gtatccgtac taactctgca ataagctgcc actctcttta ttgagcgttc aacacagcct
    19501 gatgcagttc ttttcagtgt ggtatcacct ttaataactt ttacttcttt cttcactgca
    19561 tccgcctcct tttttgtatc tttctatgca gtcttattat accacacttg caaaacatta
    19621 ttaatataat tctgttgaaa tgttgtactt tttcatcagt tttaacttta tcttcctgta
    19681 ttcaatatca tttagtaaat gtttggacag caagatagat agcatagata attggaggct
    19741 atattttagt aattcgttat tcattctaaa ccctcctcgt taaaaatcat ttttaagttt
    19801 tatgacattg gtaggtgctt ggcagcaaca taggaatctc acctccgccc cttattaaga
    19861 cgagccggct taaactattg aagtatcatt atcactactt gtatcaccga acagattgcc
    19921 acctctgttt tttatgtatt cttatttatc gctcgctttc ttatatcctt ggctaaccag
    19981 tattcataaa accgaaaact ttcagcagaa aggtcatggc gtaagtcata attctccaca
    20041 agtagataaa gtcctacctt ggtctattca gttgtcaaag atcaatattt gaaagggatt
    20101 gttttcttta cattttccta tttgccataa gcaggctatc tcttattcaa gaaagtaaag
    20161 gaggtcaaac tccccttcac tttacataag gaaaatttga cccctttggt taccgaattt
    20221 ctaaagttct tcgatgaatt ttttcagctt ttcaagaatt ttgtttcttc ttttgattaa
    20281 agccggatgt gtaatacttt tgagctttgc cactgagcga accgtttcat cattgaaata
    20341 caagcgttca ataatatctc tttcttcagc attaagcctt gatatagcat ttctaactgc
    20401 ttcaatcatc atctgtgttt caacaatctt ttctacatca acactttcat caacaatatt
    20461 atctacaaag tgtccgtcat gatccaatga tgaaaaaaag agcaagtggt tttttctgtc
    20521 cacctgctcc aaatactttt cgtgttctcg ttctcgccag tagactttgt atatctgctc
    20581 gctgacttta accctttgtc cgttgacata aaggtaatat tcttttggca tatatgtttc
    20641 ctccattctt tttttgtctg cttgttttca ggcaaaaaaa ggaggactcc tgcatcttgg
    20701 catgagaagt cctctaaaac gaaagaaact tgttctttta taaacactat ttaatttttc
    20761 aatataattt gtagattcat tatcttctat aaagcaaacc gaaaaaaggg aagaaaatgt
    20821 tcttactatt ttttattatt gaatataaag atttcttcat aatttcctcc ctcattctta
    20881 tatcgaacta atattcatat atccttatat ctaactaata ttcatatatc aaacctttct
    20941 aatagtttat tttcaccttt ggataataag atacttaaca atttatcgct tcttcttttc
    21001 caatttttct aagtctgcta agcattaaaa acaagccgag caaaatcata ctaaaatcta
    21061 caataggttc agcccaccaa actgctaatc ctccaaatac ctttggcaat agcaatatcg
    21121 ccggaataaa taaaatcagt tgtctaagca ttacaatcat gcttgctttt ttcccatctc
    21181 caatagattg gaaaaatgta agagtcataa tcataattcc atacaggata aaggtagaat
    21241 agaacaattt aaagttcata actccagctt caattatttc acttctcaca ttaaacaatg
    21301 acaataattt ttcggagaaa aacatggatg gtatccaaga aatagcagca agtattgttg
    21361 ccccatacat gaaaatcttc atagtatctt ttactctttg atattgtttt gctccaaaat
    21421 tggctcctat aacaggctgt aacccttgac tcattcccca caatggaata aatgagaaca
    21481 tataaagtct cattgttgca gacattagaa ttccccaatt atctccacca taagcgaaag
    21541 cctgtttgaa caaaaatgtt tgttgtactg caaataaaat ttgcatcatc atagccgaac
    21601 ttcctatact aaacatttca ctgtagattg ccttgctctt ttgaatttta tggataccaa
    21661 caaaagcact tttctttgaa aaatagtgaa atgttaatat cgcctgtaca atttgagata
    21721 ttacagttgc aatggctgca ccttcaattg catactctcc catcaacttc ataaaaatag
    21781 gatctaaaat aatatttaat aaagcaccta ctcccataat catcatagat tgcttcaatg
    21841 caccttcacc acgcattgtc atattgcctg cttgagcaaa attcacaaat attgaaccaa
    21901 agaaaactac tcttaaatat ctaactccca gttctttaat atttcctttt gctcctacca
    21961 aatccagaaa attaggtgca aataccaagc ctaatactgt gattactata gagaataaaa
    22021 ttacccaata acaaaaattt ccaaatattt tatccgttgt ttctttatct ccctttccaa
    22081 tagcccttga caaaatcgac gcactaccaa ctccaataag tgctgatata ccaccattta
    22141 ttattgttaa agacatcgat atactaatgg cagacatagc ataatcccct ataatccacc
    22201 cagcaaatat tccatccata aatggataaa gtcctataac aaccattcct ataattcctg
    22261 gaatagctaa ttgaaacaat aaatctttag gactttttgt taaaagttgt gttttcatat
    22321 cttgttttcc catatgactt cctcctattg tttttaatat ttttcagctt atgataactg
    22381 ccacttggtt gctacttgtc ttgcttcaac aaaatttctg taaataccat ctgtttgaat
    22441 tagttcttcg tgtgttcctt tttgcattat ctttccatta gccaatacaa gaatttgatt
    22501 tgcatttttt atagttttta gcctatgtgc aatcataatc acagttttat ttctcgtaag
    22561 ttcctccatt gcaagctgta atttatcctc attttcagga tcaacatttg ctgtggcttc
    22621 atcaaaaata ataattgggg cattttttat catagctctt gctattgaaa ttctttgttt
    22681 ttcaccacct gataaacttg caccaccttc tcctataaca gtttggtatt gttcaggaag
    22741 gttcataata aaatcatgac agcaagcctt tttagcagca tctactactt cttcatgggt
    22801 agcattaggc ttagcaaact ttatattatt ttctatagta tcttggaaca aatacacatt
    22861 ttggaaaacc atactgattt gtttcatcaa tgactctaag gaatattcct ttatattatg
    22921 tcctcctata ctaatcttcc cgttatctat atcccaaaac cttgcaatca agttacaaaa
    22981 tgtggttttt ccagctcctg aaggtccgac tattgcagtc atttggtttt gtggtatatc
    23041 aacagatata tcatcaagaa ttttctttcc tgaatatgca aattctacat tttcaaaaga
    23101 aatattaaaa ttagcaggtt ttatatcttt tccttcaata tccatttgtg gaaattcttc
    23161 taatttcttg gtttgttcaa tagagccact aacaacccta agggcagttg tcgcacttcc
    23221 tgccaattta atttgtgaaa aagcaagaaa tgaaattatg attgtcataa ctgtattcag
    23281 aaacgaaagt tctcctcttt ggtagaagaa aatacctgca cctatgatta aaatgctgaa
    23341 caaatctaaa agaatatttt gaacaatcgt gtaaggtgta aacaactttt cacaatcaag
    23401 atttgttttt ctggtatttt caatagcacc tctaactttc tcatcacctt taccggttaa
    23461 attaaaggat tttataacag acattcctcc aatctgttct aaaacagtat ctactaattt
    23521 tgctgaagcc atttgtcgtt taggaagaac ctctcttgac ttcttttcca tttttgacaa
    23581 aataaccaaa tataatagac ttccgacagt tacaataaaa cctattctcc attcaaatat
    23641 taaaatcatc aaagtaaaga ttatagtatt tataaatccc gacaaggtat ttaccataac
    23701 catcgcagcc gtattttcca catcttctaa aacggttgta gaaataccaa cgacttctcc
    23761 cccattgttt ccattaaaaa atcccatagg aatttttttg aacatttccc ctattgaaat
    23821 tcttttattt gcaaccataa aatagcttgc atggcattgt tgtaactgtg aataataatt
    23881 tgcaatactt ctgcctacta tgcttacaac aagaagtatc aaagcaatcc acgcaggtgt
    23941 catactcata tctttttcag aaacagcttt aactataaaa taaattgcac tgatttgaag
    24001 catgtgaaaa attgcaaaca agaaacttac ccatatagaa tggtatatat ttttcttctc
    24061 atcacctgag aaatctaaaa ttttttttaa agcacttagc attttatttc accatccttt
    24121 actccaatat gagcattcca cattttttta tatagctcac aatcttccat taactcgtta
    24181 tgtttaccat gtgaaataag ctctccattc tcaacaaaaa agatttgttg aacatctgtt
    24241 attgttgata acctgtgtgc aataacgata acagttttat tttgtatcaa ttttgataga
    24301 gcttctttga taatcacctc attctccgga tcaatatatg aagttgcttc atccaatatc
    24361 actatcgggg attttttaag cattgctctt gctattgaga ttctttgtct ttctcctccg
    24421 gaaatatggc taccactgct tccgacaact gtgtcatagc ctttttccat attcataata
    24481 aaatcatggc agcctgactt ctttgcaata ttttcaactt ctttatcact tgcacttgga
    24541 tttcccattc gtatgttttc cctaatgctt tcattaaaaa ggaaattgtc ttgagaaaca
    24601 aatgctacta agctatataa ctgtttaaga ggaatctctt ggagattata tccaccaatt
    24661 tttatgcttc ctgtatttat gtcccaatat cctgctatca gttttgccaa agttgacttt
    24721 ccactaccgc tcggtccaac aaaagctatc gttgtccctt cttctatgtt taacgacact
    24781 ccatgaagaa tttcctttcc ttcttcatat ccaaacttca catcttgcag agcaatatca
    24841 tatttgttta ttttcacatc aacattggaa tgaatttgct cttttccttc taaaattgaa
    24901 ttaata
//
LOCUS       DAVHSI010000030        24439 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.030, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000030 DAVHSI010000000
VERSION     DAVHSI010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.030"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            27..887
                     /locus_tag="VVR21_001419"
     CDS             27..887
                     /locus_tag="VVR21_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055286.1"
                     /translation="MVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQEYCQGQPY
                     GLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQSYLGSNTA
                     WIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAIFENLLDSY
                     LLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYDNEALRDLS
                     KQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDRFFYKDRPY
                     IFSRKSPIKG"
     gene            1202..2179
                     /locus_tag="VVR21_001420"
     CDS             1202..2179
                     /locus_tag="VVR21_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055287.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            2556..2930
                     /locus_tag="VVR21_001421"
     CDS             2556..2930
                     /locus_tag="VVR21_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU6055288.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALPAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3138..4040
                     /locus_tag="VVR21_001422"
     CDS             3138..4040
                     /locus_tag="VVR21_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055289.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEAILGKI
                     VDSESTLLCIGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4096..4449
                     /locus_tag="VVR21_001423"
     CDS             4096..4449
                     /locus_tag="VVR21_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU6055290.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGTYLSKRACQGICVALAMSPGT
                     FIALAGAAVLTKKLINYIKVGSFGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWNGFISVTVR"
     gene            4446..5174
                     /locus_tag="VVR21_001424"
     CDS             4446..5174
                     /locus_tag="VVR21_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055291.1"
                     /translation="MNNVDKIRKIHIIVYWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6301..6804
                     /locus_tag="VVR21_001425"
     CDS             6301..6804
                     /locus_tag="VVR21_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055292.1"
                     /translation="MKLLDCILDYQERFNRKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDFASHTISVIQTGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKLTSCC
                     IVAKDLSKNTMKLDVIFFEDKNKISAVLGLRRDKSGVFKPVTLYFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            7090..9006
                     /gene="pspA"
                     /locus_tag="VVR21_001426"
     CDS             7090..9006
                     /gene="pspA"
                     /locus_tag="VVR21_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEU6055293.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVANQSKAEK
                     DYDAAKRDAENAKKALEDAKRAQKKYKDDQKITEEKAEEEKKASQEQQKANLDYQQKL
                     RKYINEKDSKKRSMLQKEMEEAERKDKEKQAEFKKIREKVIPSAEELTETRRKAEEAE
                     AKEPELTKKVKEAEEKVTEAKQKLDAERAKEVALQAKIAELENEVHRLETKLKEIDES
                     DSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     YSALYLEAAEKDLAAKKAELEKTEADLKKAVNEPEKPAPAPETPAPEAPAEQPKPAPA
                     PQPAPAPKPEKPAEQPKPEKTDDQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPAPQP
                     EQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSW
                     YYLNANGAMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGDMATGWLQNNG
                     SWYYLNANGAMATGWAKVNSSWYYLNANGAMATGWAKVNSSWYYLNANGAMATGWAKV
                     NGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNT
                     TVDGYEVNANGEWV"
     gene            9407..10528
                     /gene="mnmA"
                     /locus_tag="VVR21_001427"
     CDS             9407..10528
                     /gene="mnmA"
                     /locus_tag="VVR21_001427"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU6055294.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTRDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            10669..11067
                     /locus_tag="VVR21_001428"
     CDS             10669..11067
                     /locus_tag="VVR21_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6055295.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAF"
     gene            11134..13047
                     /gene="mnmG"
                     /locus_tag="VVR21_001429"
     CDS             11134..13047
                     /gene="mnmG"
                     /locus_tag="VVR21_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU6055296.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFENEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(13426..15105)
                     /locus_tag="VVR21_001430"
     CDS             complement(13426..15105)
                     /locus_tag="VVR21_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU6055297.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(15107..15340)
                     /locus_tag="VVR21_001431"
     CDS             complement(15107..15340)
                     /locus_tag="VVR21_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU6055298.1"
                     /translation="MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            15724..15942
                     /locus_tag="VVR21_001432"
                     /pseudo
     CDS             15724..15942
                     /locus_tag="VVR21_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16158..16310)
                     /gene="cibB"
                     /locus_tag="VVR21_001433"
     CDS             complement(16158..16310)
                     /gene="cibB"
                     /locus_tag="VVR21_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU6055299.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(16312..16497)
                     /gene="cibA"
                     /locus_tag="VVR21_001434"
     CDS             complement(16312..16497)
                     /gene="cibA"
                     /locus_tag="VVR21_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU6055300.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            16675..17358
                     /gene="tsaB"
                     /locus_tag="VVR21_001435"
     CDS             16675..17358
                     /gene="tsaB"
                     /locus_tag="VVR21_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU6055301.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLVHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            17355..17792
                     /gene="rimI"
                     /locus_tag="VVR21_001436"
     CDS             17355..17792
                     /gene="rimI"
                     /locus_tag="VVR21_001436"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU6055302.1"
                     /translation="MIEIKRIQQQPALAQDIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRGQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            17782..18792
                     /gene="tsaD"
                     /locus_tag="VVR21_001437"
     CDS             17782..18792
                     /gene="tsaD"
                     /locus_tag="VVR21_001437"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU6055303.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(18832..20138)
                     /locus_tag="VVR21_001438"
                     /pseudo
     CDS             complement(18832..20138)
                     /locus_tag="VVR21_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(20413..20786)
                     /locus_tag="VVR21_001439"
                     /pseudo
     CDS             complement(20413..20786)
                     /locus_tag="VVR21_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20893..21186)
                     /locus_tag="VVR21_001440"
                     /pseudo
     CDS             complement(20893..21186)
                     /locus_tag="VVR21_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            21429..22109
                     /locus_tag="VVR21_001441"
                     /pseudo
     CDS             21429..22109
                     /locus_tag="VVR21_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            22235..23851
                     /locus_tag="VVR21_001442"
     CDS             22235..23851
                     /locus_tag="VVR21_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055304.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            24111..>24439
                     /locus_tag="VVR21_001443"
     CDS             24111..>24439
                     /locus_tag="VVR21_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055305.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLY"
BASE COUNT         7716 a         4083 c         5123 g         7517 t
ORIGIN      
        1 ttataagaaa aaaatctttt aagtatttgg ttctatatcc atttacttat gatgggagct
       61 ggagatttca acctataaac ttactctact ttccagaaat ggtgagagat gtcattccga
      121 ttaatttagt tcaagaatat tgccaaggac aaccttacgg actgttaaaa aagatgctga
      181 aaagaattcg attgtcacga gagatagctt tactcctggc taccattatc gtctattttt
      241 ttacgcatag aattctacct ctttcagtat ttacgttcat gttctcttac atattgctat
      301 ttgtacaatc ttatttgggt agcaataccg cttggattgg aaatagaaga ttaataatag
      361 atgatgaatt tgaaaaaatc ttgctttcaa aaagttatgt aaaagaaata tcatctgcac
      421 gatactcaga atacttgaca tgtgaataca aaaaccttac accaatcata ttgatagcta
      481 tttttgaaaa tttgcttgac tcctacttgc ttcagaatca gagtgaggtt gacttagata
      541 ttttttataa agttttacct ttgctttata aagaaaaata tactatggga ttcaattact
      601 ttgtaagttt aaattattta ctatataagg ttggattttt gggaatcatt tacgataatg
      661 aagcattaag agatttgtca aaacaatatt taaacaaaaa tatttcggaa ttacaagatg
      721 gttctttcga gggcggtata caagatgctg ttgcctctaa acaaatagta gttataaatg
      781 aatttatagc ttgtttaaat tccagatgca tgccatccca atatgataga tttttttata
      841 aagatagacc ttatattttt tccagaaaga gtcctattaa ggggtgaaaa tttgttacat
      901 ttggattaac aagtgtccta gggattagaa ataactctag tatagctaga tatttttgag
      961 taactagaaa tatcattagg ctactcatat gattgccaga aaagatggct gatgaatctt
     1021 atttatactg ttgcagtagg cgttgtctag gataaataag ctatcttgat gggggagatt
     1081 ggaataattt tagtagaaac attaaaggat tatgggcaag tagcatagga ttaggtgatg
     1141 caatgtgcta agttggcttg gtgttagcag tagtattatt taacaatgga aagtagacta
     1201 aatgaaaaat aagcgttatt tttttgacac aattttaata attttactgc ttataagcac
     1261 gatattttgt gtcagcccag tatttataaa attggacatc ttaggaactc cctctcatgc
     1321 catcttaacc tttgtattgg cgataccgtt attctatatt ttgtctcaat gcttacatac
     1381 tttgctatta ctagtttcct caatcttttg taaattaaga ccaatttatt tttattttat
     1441 atttgtgatc attataggag ctaggaaata ctatcgaatt ctctttcacc aactaatggg
     1501 atttagtcca ggaatagcag tgttttataa ggagagtcaa acaactaaga atctgtttaa
     1561 attttactac ttcttgtact ttacaacact aatttcatac tattttttct ttacttttgt
     1621 gtatgacaaa ccgttgcttt tgcctcttat ttcattttct attatcatag cattagtaca
     1681 aaaactttat agaattgaga atcaacaatt atttctgtta aaatcaaagg tactaacaat
     1741 actggaatct aagaagaatt gtgagtttaa tcttcaggat tatcatgaaa tttggaaatt
     1801 gcaatcaaaa tctgagttgc catgcgtggc tttatcttat atcagtttaa tcaagccata
     1861 tctttcagag agtgtgcgtg aacaaattga tttattagaa gttaagcgat ttaaaaaaat
     1921 aaataatcca atatcacttt atggtatgtt ggatgttata aaattaaatc tatatttacg
     1981 gcattataat gaaaaaaata aatatgaatc aatgttaaag aaaattttag aggtaagacc
     2041 agactttgtt ttaatcgagc agaatattga tgatagttta aatagctcgc aaccattatc
     2101 tttatcttta gccatttcag aaatccaact tttgcttgaa gtgtatatag ggatcaaaca
     2161 tgtttcaatt aggagataaa actagaataa tatttgccat tataggggca agttgcatat
     2221 tagtcagtat gtatcttatt ccacttatta aaactgagaa taaattttgg gaaatacttt
     2281 tatttatatt aggtgtattg ctaattggaa ttgcgttact aagtcaaaaa aaataaattt
     2341 tgaaatagta ttagtgagtt cgcaatcatt tattgctagt ggtttagaac tgttaagttt
     2401 caaacaataa ttgattttaa accttaggta acctataaaa acaaataagg tagagaaagg
     2461 atatcttatc taggtagcta agtgataaaa acacagtcgt ctatcacttg ttaggaaact
     2521 atcctaacta tgcttaataa aaaaggagaa aataaatgga actcgtatta ccaaataatt
     2581 atgttgttct tgagcaagaa gagatgatgt atcttgatgg gggattttct attccgagat
     2641 ggcctgttgc aacagccatt aatatagctt ttaatggtgt tttaggtgga ggagcaatca
     2701 gtctagttag aaattatatt cgtaattatg gtttgcggcg agttacaagc gcaattgctg
     2761 gagcagctgc aagatatgtt ggggtacgag ttgcaaatag agtggcagga tttgcactgc
     2821 ctgctattaa tggatttgca gcttggatgt caattggcga tgctattaca acaatctggg
     2881 ccaataatga tgtaaatagg agagacccaa atttaaacgc cttgtggtaa ctagatatgg
     2941 gtattaaaat ggaaaaaatt tttgttatta ttttttttgt atgtctattt atatcatcca
     3001 taactttttt agcctatgat tttgttagcg aagaaataaa aaagttgatt atttggatta
     3061 atgtcgtttt tttgatttta atcatagcaa tgatgattta tccaaaatta agaaaatgat
     3121 aaggacactg taaaattatg atacgtaaac taattgtttt cttactaatg ctccctcttt
     3181 ttgtcttgtg gctagagttg catgtcctag tgaataactt actattgaat ctagaatctc
     3241 cccttgattt tgtgattagt atgagtcttg ctttctgtag tttgatttta tcaaaaatag
     3301 ttttagacat actatacgca ttgaaagatt tatacaagaa agaaggtctt attaagattt
     3361 ttccctttat ttttataaga aggaaaaaag tgaatgtgag attctcgccc tatttttcat
     3421 tccatcgtaa aagtttgtcg cctgatgatt taagatctag gattatatgg agttttattc
     3481 ttgaaattgc tattatccta gtatttattt taaaaattcc ttttgcaatc atcatgctta
     3541 ctacaatatt tttctggact ataatggata tcaatcatct agtttttaat aagacggaat
     3601 ttctttttaa tcaaaacaaa tggcaaaaag aagattcgtt tgaaagtgat ttgacgaaaa
     3661 cgttaaagga taaaatacaa aagtcagagc taagttattc tgacttaatg tctctacagc
     3721 tgtatgatgc gatgaaccaa tccacctttt taacggatag tgaactcttt gaggctattc
     3781 tgggaaaaat tgtagattct gagagcactc ttctttgtat aggacttgta gagttgctgc
     3841 tatatgaaat ttctattagt aacaataaca actggtccaa caaggttgat aaaattagga
     3901 tacacctcat cagaatcaat caattagatt ttttctatta tacaagttgg ttaaggcaaa
     3961 attttgattt ctgtatgaat agagagtatc ataaaatgaa atctcggaaa ttattactga
     4021 gtaataaaaa gatagtttaa gttcgtccta tttgtaaaac aaatgaaaca atttcaacta
     4081 aggaggagaa aacaaatgga acttgtatta ccaaataatt atgttgtgat tgatgaagaa
     4141 gaaatgatgt atcttgatgg gggaacttat ttaagcaagc gtgcttgtca aggaatttgc
     4201 gtagctttag ctatgagtcc aggaactttt atagcattag ctggagctgc agttttaacc
     4261 aaaaaactaa taaactatat taaggttgga agctttggag gctggcttat tggtgcagca
     4321 gcaggtgtat tggctacagc agcaggaaaa atagcttact gtattggata tggtgctctt
     4381 aatagaggtt gtgatattag cgggaaccct tatccttgga atggattcat atctgtgaca
     4441 gtaagatgaa taatgtagat aagattcgaa aaatacacat catcgtgtat tgggtgtata
     4501 tatttttatc attcagggcg attataaatg atacggagta ttttttgctt atttttttag
     4561 cttttatcta ctcaatagta tcactacctc tatattctgt gaaaaataaa atagtatcta
     4621 tctgtctagc cataaattcg attctgttaa tgagtttccc cattttaatc aataagtttt
     4681 tcccagaaag ttttttgact tataccgtat taataagtgt ttttattaca gagttgataa
     4741 tttttcattt aattgggaaa gattttgcta ctaaattgac taacgaatat aagaaaatta
     4801 gtcagtttag aagcaaggtg tctcaatctc cttggataaa atatttagag atttctagtt
     4861 ttatattaac tatatttcca tctattcttt atggtacagt tgataatcgt gtattggctc
     4921 ttatcttttt gataaaaatt tgtgtagata ctacgataaa atttttattc atcagattat
     4981 ttgacacaag tactttaatg aagaggagga tattttttct tttcgcattg gatgttatag
     5041 cttacttatt tttaggatat cttttagtga ttcaaaaagc aggctatttg ttttcggttt
     5101 tacttctttt ttctaatttt tcagttccat ttatcaaaga aaaggaatac gaattattta
     5161 aaaatagcaa gtaatagaaa cataggttaa atcttagaac ggcttaaaat cagatatgat
     5221 aaagggaaat agtcttatct aggtaactaa gtgctacaaa cacagtcgag gatcacttgt
     5281 taggattaca ttttaatcat gcttaataag aatggagaat tcctatgggg attgtattac
     5341 tctgaagttt cgaatacctt agttctcgtg attttgagct attctagctt tagaatcctt
     5401 cagaacgtaa aattttaagc agtcaaagac ttagaatagc ccgaaaacat ttattttata
     5461 acaattctaa gcttagaatt gctcatatat atgtatttga gctgctcgat agttaggaca
     5521 gctttattct gagaaatctg agctatcaat gcttcagaat agtatttcgc caatggtttt
     5581 tattgaagag gtgattgttt tatgatagtc taaaataaaa ctgatttaat ggagaatcgt
     5641 tacatgaaac atttttttgc aggaattggt gagataaaac ttgttggcta cttattgtat
     5701 atatgtgtag gactagcccc tctttttcat atatatgtca taggttcgga actgagtttt
     5761 gtgaaaatag tgttatctat tttgggaatt atatttgtaa gtatgttaac tattgctcga
     5821 atttatagga tttttttcta taaagaatag tttggacttg aactgtatct aaaaacagag
     5881 attggtcgat tatcagcctc tttcttgtcg ttgaaaagag tgagatatat tgacttttga
     5941 aaaaaagatg tcataattga gttgggataa acctaaaaat aatatagtag attgaatctg
     6001 gaatagtccg ttatgaccgt taaaatattt ctagaaatta atttgacttt cctaatcgat
     6061 ttgttcacat cttgtttcaa tctactatac tttctcgtta aaccgttcgg caattcatgg
     6121 tgacatggac acatagtagt aagcacacta tgtggcttgg cagagctaaa aactgttccc
     6181 ttgcgataag cctaataagc acaacatagg gagttagaga agccgactct aatcaaacac
     6241 tttgggcagt agtgagaact gccccgtgct ttttattttg agaaaatatg gagtttgtcg
     6301 ttgaaattac ttgattgtat tttggattat caagaaagat tcaatagaaa aacatgtcaa
     6361 gtatcaacga attataagta tttagagact ttcaaagtga atttttgcct gactgattta
     6421 catcatttat ttggcttaca caaaatcaca cgagattttg ctagtcatac gatatctgtt
     6481 attcaaactg gtgtttttat tttagaagat tttagaaata tcctattgta caatgatgta
     6541 atcgaaagga tatctttata tgagtttatc ggcgatatct tctattctaa gctaacaagt
     6601 tgttgcatcg tagctaagga tttatctaaa aatactatga aattggacgt catatttttt
     6661 gaggataaaa ataaaatatc cgcagtttta ggtttacgaa gagacaaaag cggagtattt
     6721 aaaccagtta ctctatattt tacaagcgct aagaaatatg ctaaagttcg taaaacagat
     6781 gtgaaagaaa tgaaatggct ataaagattg tccgcaggct taagcttgcg ttttttgttg
     6841 tttaacgaaa ttaaaaaata agctctctca ttggaaatgt ttttatagga atgaaggaag
     6901 atgatgctat gtttaaaaag agaatcgaaa agggcaaaag tagtgtcttt atctttttgg
     6961 agtagaagct tatgatatag aaatttgtaa taaaaatgta atataaaaca tttgacaaat
     7021 atttacgggg ggagtatact taatataagt atagtctaaa aatgactatc agaaaagagg
     7081 taaatttaga tgaataagaa aaaaatgatt ttaacaagtc tagccagcgt cgctatctta
     7141 ggggctggtt ttgttacgtc tcagcctact tttgtaagag cagaagaagc tcctgtagct
     7201 aaccagtcta aagctgagaa agactatgat gcagcgaaga gagatgctga gaatgcgaaa
     7261 aaagctttag aggacgcaaa acgtgcgcag aaaaaatata aggatgatca gaagataact
     7321 gaggagaaag cggaagaaga aaaaaaagct tctcaagagc aacaaaaagc aaatctggac
     7381 tatcaacaaa agttgaggaa atatattaac gaaaaagact ccaaaaaaag atctatgctt
     7441 cagaaagaaa tggaggaagc tgagagaaaa gataaggaaa aacaagcaga atttaagaag
     7501 attagagaaa aggtgattcc tagcgcggaa gagttaacag agactagacg aaaagcagaa
     7561 gaggctgaag caaaagaacc agagcttact aaaaaagtaa aagaagctga ggaaaaagtt
     7621 actgaagcca aacaaaaatt ggatgctgaa cgtgctaaag aagttgctct tcaagccaaa
     7681 atcgctgagt tggaaaatga agttcataga ctagaaacaa aactcaaaga gattgatgaa
     7741 tctgactcag aagattatgt taaagaaggt ctccgtgctc ctcttcaatc tgaattggat
     7801 gctaagcaag ctaaactatc aaaacttgaa gagttgagtg ataagattga tgagttagac
     7861 gctgaaattg caaaacttga aaaagatgta gaagatttca aaaactcaga cggtgaatat
     7921 tctgcattat atcttgaagc tgcagaaaaa gatttagctg ctaaaaaagc tgaattagaa
     7981 aaaactgaag ctgacctcaa gaaagcagtt aatgagccag aaaaaccagc tccagctcca
     8041 gaaactccag ccccagaagc accagctgaa caaccaaaac cagcgccggc tcctcaacca
     8101 gctcccgcac caaaaccaga gaagccagct gaacaaccaa aaccagaaaa aacagatgat
     8161 caacaagctg aagaagacta tgctcgtaga tcagaagaag aatataaccg cttgactcaa
     8221 cagcaaccgc caaaagcaga aaaaccagct cctgcaccac aaccagagca accagctcct
     8281 gcaccaaaaa caggctggaa acaagaaaac ggtatgtggt acttctacaa tactgatggt
     8341 tcaatggcga caggatggct ccaaaacaac ggttcatggt actacctcaa cagcaatggt
     8401 gctatggcaa caggttggct ccaaaacaat ggatcatggt attacctaaa tgctaacggt
     8461 gctatggcaa caggatggct ccaaaacaat ggatcatggt actacctcaa cagcaatggc
     8521 gctatggcga caggatggct ccaatacaat ggttcatggt actacctcaa cgctaatggt
     8581 gatatggcga caggatggct ccaaaacaac ggttcatggt actacctaaa cgctaacggt
     8641 gctatggcaa caggttgggc taaagtcaac agttcatggt attacctcaa cgctaacggt
     8701 gctatggcaa caggttgggc taaagtcaac agttcatggt attacctcaa cgctaacggt
     8761 gctatggcaa caggttgggc taaagtcaac ggatcatggt actacctcaa cgctaacggt
     8821 tcaatggcaa caggttgggt gaaagatgga gatacctggt actatcttga agcatcaggt
     8881 gctatgaaag caagccaatg gttcaaagta tcagataaat ggtactatgt caatggctta
     8941 ggtgcccttg cagtcaacac aactgtagat ggctatgaag tcaatgccaa tggtgaatgg
     9001 gtttaagccg attaaattaa atcatgttaa gaacatttga cattttaatt ttgaaacaaa
     9061 gataaggttc gattgaatag atttatgttc gtattcttta ggtacctatc ttatgatttc
     9121 aggaaatgtc attaaaaaaa cgactccttt tctctaactt gaaaaataga ttagagaaaa
     9181 ggggttgttt tatttattat agttatttga atgaagataa gaagaaggta tactcacgtc
     9241 attcacatga tctgtatatt gactataagt tttaaaaaac aatttttaag ctcttccttg
     9301 tcttctctaa ccaagcgtgt tataatgaat actgctcaag cgaccttcaa tcgtgaagca
     9361 cacacgacct tcaatcgtga ataaacgaat agatgggaga cttaccatga gtgataactc
     9421 taaaacacgt gttgtcgtgg ggatgagtgg tggtgttgat tcgtcggtga cggctcttct
     9481 tctcaaggag cagggctacg atgtgatcgg tatcttcatg aagaactggg atgacacaga
     9541 tgaaaacggc gtctgtacgg cgaccgaaga ttacaaggat gtggttgcgg tggcagacca
     9601 gattggcatt ccctactact ctgtcaattt tgaaaaagag tactgggacc gcgtttttga
     9661 gtatttccta gcggaatacc gtgcgggacg cacgccaaat ccggacgtta tgtgcaacaa
     9721 ggaaatcaag ttcaaggcct ttttggacta tgccatgacc ttgggggcag actatgtagc
     9781 gactgggcat tatgctcgag tggtgcgtga tgaggatggt accgttcaca tgcttcgtgg
     9841 cgtggacaat ggcaaggatc agacctattt cctcagccaa ctttcgcaag aacaacttca
     9901 aaaaaccatg ttcccactag gacatttgga aaagcctgaa gttcgaaaac tagcagaaga
     9961 agcaggcctt tcgactgcta agaagaaaga ctcgacaggg atttgcttta tcggagaaaa
    10021 gaactttaaa aactttctca gcaactacct gccagctcag cctggtcgta tgatgactgt
    10081 ggatggtcgc gatatgggcg agcatgcagg tcttatgtac tatacaatcg gtcagcgtgg
    10141 cggactcggt atcggtgggc aacacggtgg tgacaatgcc ccttggttcg ttgtcggaaa
    10201 agatctaagc aagaatattc tctatgtagg ccaaggtttc tatcatgatt cgctcatgtc
    10261 aaccagccta gaggctagcc aagtccactt tactcgtgat atgcccgagg agtttacgct
    10321 agaatgtacg gctaaattcc gttaccgtca gcctgactct aaggtgaccg tccatgtcaa
    10381 aggagacaag gcagaagtta tctttgcgga accacaacgc gcgattacac caggacaggc
    10441 agttgtcttt tacgatggcg aagagtgtct aggtggtggt ttgattgaca atgcttaccg
    10501 cgatggacaa gtttgtcagt acatttagat tgacaaattt tctcaatttg ctacaataat
    10561 aacagcaata gaaatgatgg tcaaagctca tggatgttgc aggctttttt gtcctgcact
    10621 tctttgtagt tttgactgtt tttgtgtcgt ttaagggaaa ggacaagaat gactcaacaa
    10681 gactttcgga caaaagtaga caatacggtt tttggtgttc gggctacagc cttgattgtc
    10741 caaaatcaca agcttctagt taccaaagac aagggcaagt attacactat tggaggtgcg
    10801 attcaagtca atgaaagcac ggaagacgcg gtagtccgtg aagtgaagga agaactgggt
    10861 gtcaaagctc aagctgggca gctagctttt gtggttgaaa atcgttttga acaagacggc
    10921 gtttcctatc acaatatcga gtttcattat ctggtggatt tgcttgaaga tgccccgttg
    10981 accatgcagg aagatgagaa aaggcagccc tgtgagtgga ttgacttgga taagcttgag
    11041 gatatccagc tagttccagc cttttaaaaa acggccctac cagattggga aggccaacta
    11101 agacacatcc atcttgagaa ataggagaga aatatgacat atcattttac tgaagaatac
    11161 gatattattg taattggtgc gggacacgct ggggttgagg cttccttggc cgctagccgt
    11221 atgggctgta aggtcctgct tgcgaccatc aatattgaaa tgctggcttt catgccttgt
    11281 aatccctcta tcggtggttc tgccaagggg attgtcgtgc gtgaagtcga tgccctcggt
    11341 ggcgagatgg ccaagactat tgacaagact tacatccaga tgaagatgct caacacaggg
    11401 aaggggccag ctgtccgtgc tcttcgtgcg caggctgata aggaacttta ctctaaggaa
    11461 atgcgcaaga cagttgaaaa ccaagaaaat ctgacccttc gtcaaaccat gattgatgag
    11521 attttggtgg aagatggcaa ggttgtcggt gtgcgtacag ccacccatca agaatatgct
    11581 gctaaggctg ttattgtgac gacagggact gctctccgtg gggaaattat catcggagac
    11641 ctcaagtact catcaggtcc taaccacagc ttggcttcta ttaacctagc tgacaatctc
    11701 aaggaactgg gcctcgaaat cggtcgtttc aagacaggaa cccctccacg tgtcaaggct
    11761 tcttctatca attacgatgt gacagaaatc caaccaggag atgaagcgcc taatcacttc
    11821 tcatacactt cacgtgatga ggattatgtc aaggaccaag tgccatgctg gttgacctac
    11881 accaatggta ccagtcatga gattatccaa aacaacctcc accgtgcgcc tatgtttaca
    11941 ggtgtggtca agggagtggg gcctcgttac tgtccgtcga ttgaggacaa gattgtgcgc
    12001 tttgcggaca aggaacgcca ccaactcttc cttgagccag aagggcgcaa tactgaggaa
    12061 gtctatgtgc aaggactttc aaccagtctg cctgaggatg tccagcgtga cttggttcat
    12121 tccatcaaag gtttggaaaa tgcagagatg atgcggacag gttatgctat tgagtatgat
    12181 atggtcttac ctcatcagtt gcgtgcaact ttggaaacca agaaaatctc aggtctcttc
    12241 actgctggtc agacaaatgg aacgtcaggt tacgaagagg cagcaggcca agggattatc
    12301 gcgggtatca atgcggctct gaaaatccaa ggcaagcctg agttgatttt gaagcgcagt
    12361 gatggttata taggggtgat gattgatgac ttggtgacca agggaaccat tgaaccctac
    12421 cgtctcttga ctagtcgtgc tgaataccgt ctcattcttc gtcatgacaa tgctgatatg
    12481 cgcttgactg agatgggacg cgagattggc cttgtggatg atgaacgctg ggctcgtttt
    12541 gaaatcaaga aaaatcaatt tgaaaatgag atgaagcgcc tagatagcat caaactcaag
    12601 ccagtcaagg aaaccaatgc taaggttgag gaaatgggct tcaagccgtt gacagatgcg
    12661 gtgacagcca aggaattcct tcgccgtcca gaagtttctt accaagatgt ggtggccttc
    12721 atcggaccag ctgctgagga cttggatgac aagattatcg aattgattga aacagaaatc
    12781 aagtatgaag gctatatttc caaagccatg gaccaagttg ccaagatgaa acgcatggaa
    12841 gaaaaacgca ttccagccaa tattgactgg gatgacattg actctatcgc aaccgaagct
    12901 cgtcagaagt tcaaactcat caatccagaa actatcggcc aagccagccg tatttcggga
    12961 gtaaacccag cagatatttc tattttgatg gtgtatctgg aaggtaaaaa tcgtagtatt
    13021 tctaaaactc ttcaaaaatc aaaatgatac gtcgtcggct gcttacgaat gagttcaaag
    13081 cttggctttg attcatctcc aacctcccat agttccccga actatgggag ctaactcaag
    13141 ttatgcattt tcctagcctt ctggtctgat tttcattgag ttttaatctc aaaagaaagc
    13201 atagagaaaa acagctccga agacggggct gttttgttga cttgtactca atgaaaatca
    13261 aagagcaaac taggaagcta gccgtaggtt gctcaaagca ctgatttgag gttgtagata
    13321 gaactgacga agtcagctca aaacacagtt ttgaggttgt ggatagaatt gacgaagtca
    13381 gtaacatata tacggcaagg cgaagctgac gtggtttgaa gagtattatt cttcatctgg
    13441 tgtgaggatc atcgggatga tgatcggttc acgttcggta ttttcataga ggaaggggcg
    13501 aatagcgttg acaatggcac cattgacaga ttgcacgcta gcatccttat ttttcagtgc
    13561 gatacgaatg gcattgaaga ggatacgctg gctttggcga atcaagtcgc cagactctct
    13621 catgtagaca aagcctcggc tgaggatgtc tggaccagat agaatcatct gcgatttgaa
    13681 gtcaacagtt gcaactgcca gaacgacacc gtcttcagat agatcgcgac gatctttgag
    13741 gacagctgcg ccaatttcac cgatacgatt tccatcgaca tagatatctt gggcgttgaa
    13801 atgacctgcg atacgagctg agtcagcagt aagggcaagc acatcgccat tgctcatgat
    13861 aaagatattg tccttctcaa caccagtatc cactgctagt ccagcgtgga ctttttgcat
    13921 gcggtattca ccgtggacag gcatgaagta ttttggctta atcaagcaga gcatgagttt
    13981 ttgctcttgc tgaccaccgt gtccagatgt atggatattg ttcactttac cgtggataac
    14041 ttcgacacca gcttcagaaa tgatgttaat cagcttgttg acgctagtag tgtttccagg
    14101 gatgggacta gaagagaaga taacggtatc acctggttgt aattgtactt gacggtgggt
    14161 tccgttggcg atacgagaga gggctgccat aggctcaccc tgactacctg tacagaggat
    14221 aagaacttct cctgcaggat aatctttgat ttcatttggc tcgataaagg ttcccttagg
    14281 agctttgatg tagccaagat cgattccgtt gacaatggcc ttttccatag aacgaccaaa
    14341 gaccgcaatc ttgcgtccag tcttaacagc agcttctgtt gcctgctgga gacggaagat
    14401 atttgaggca aaggatgcaa agatgatacg tccttcaata ccttggataa tcttcataat
    14461 ggactgacca acgacttttt cagagttggt aaaggttggt acttccgcat ttgtcgagtc
    14521 agacaggaga cagagcacgc cttcttcacc aagcgcagcc atacgatgca agtccgcagg
    14581 ttctccaact ggagtaaagt cgaacttaaa gtcacccgta cagacgattt tcccttgagg
    14641 agtatgaatg acaatcccca aaggctctgg aatagagtga gtcgttctaa agaaagttgc
    14701 cttgagattt ttaaaggtca actcggtgtt gtggttgatt tcgtaaagtt tggcgttgcg
    14761 caagaggccg tgttcttcga gtttcccacg gatcaaagcc aaggcaagcg gtccagcgta
    14821 gatagggaca tttgcttgct tgagtaggaa cggaatccca ccaatgtggt cctcgtgtcc
    14881 gtgtgtgatt aaaacagcct tgacgcggtc gatattgtcc acgatgtaag agtagtcagg
    14941 aatgacatag tcgataccaa gcaagtcatc ttctgggaat ttaatcccag catcgacgat
    15001 gataatctcg tcttggtatt caattccgta agtgtttttc ccgatttctc ctagaccacc
    15061 gatggcaaaa acgccgactt cttcaggttt aagagtgtag gccatattag aactccgtaa
    15121 tttcgaaggc gccagtttct ttttcgtaat cgagcaattt gtcagacaag agttcgatat
    15181 actcgatatt gtactctggg cgattttctt cgacaagttg gcgagcagtg atacggccct
    15241 caagttctga gctggcatcg atgtctaggt aaagcgtgcg tgttgtttca cggcgtgggc
    15301 tacgttcttt tgtttcttga taaaaaactt tgtaaatcat atagttcctt tctatttaca
    15361 ggtcagctta ttccaaactt ttagcagata tttgcttgat ttcattccat tttgtgtcta
    15421 gattgacctt gattcgttac aattatttca attataccac aaaatgaaaa attagtaaaa
    15481 gacggaaacg agaaagttag gggacgattt ctttggtaag cgtttgcaaa aataaagaaa
    15541 atgtattatg ttgataacgg aagtgaaatt tattgcttgt cataattcca tatagatttt
    15601 aagtcaagga ggttgcccta tgtataactt atttgctttt gctatcggag ctcgcttggt
    15661 agcttttatt gtttttgttg cttgcgttta tgcggggaat cttctatttg ccaaactgga
    15721 acgatgacaa accaagttct tgtggaaaat gacctttgtg actctctact cgctttttct
    15781 cctcctcatg acctatgtcg tttggtttgt attttacttt ggattaaatg cttagatgcc
    15841 ctgcttatgc tggggttttt tgtttgggga tgtagagata gtagatttac gacacgaaaa
    15901 ttctacccca tctatcaaga tgaggtggtt tttgtatttt ttagaaatga catgataatg
    15961 gtattttcag agcttattag ttttatggta atcattcttc tgctcaaaaa tagagttgaa
    16021 gcataaaaat aaaacaatac aaacagataa atcgaatggt aaagggatag tagtaatgtt
    16081 caaatcattg agaatgctga gcaaactgta agagatgaag acaataaaat ttatccttct
    16141 aaaaatgtgt ttcttatcta gcatgattta ccaaactttt tacgaaggtc ttttccaatg
    16201 gtataacctg ccataaataa agcgatacca acacctacac caaagccacc cttgatttct
    16261 tgcaattcct tattagaaat ttcacgatag ttgttcaaat ctttcatcat attaatctcc
    16321 tcctaaaaaa taaccagctg ccaaaccaga acctataagt gctgttccac ctgcaatagc
    16381 cttccaagat actgctactc caaagataac caagggagcg agaccgccat caatatctga
    16441 taattcattt tcagataagg ataaaaattg attgtcaaga atgtcaaaat ttgtcattga
    16501 attttcctcc ttttttcttg ttcactttta tattcggaaa agaaaaggaa aagtgagcat
    16561 ttttttaaat tatttttagt taagtgaggg cactcttgtc tgggggcaaa gaaaattccc
    16621 atgtgccagc ttttgtagta taatagtaag cagacaaaaa gataggaatg tgttatgaaa
    16681 gtattagctt ttgatacgtc cagcaaggct ctttctctcg ctattttaga ggacaagcag
    16741 attcttgccg agatgacgat taatattaag aaaaatcaca gtattaccct catgcctgcc
    16801 atcgattttt tgatggcaag tttggactgg acacccaagg atttggaccg aatcgtggtg
    16861 gctgaagggc caggtagcta cacaggcttg cgaattgcgg tagccactgc caagactttg
    16921 gttcatactc tgaacatcga gttagttggt atgtctagcc tcttggctct ggtaccctac
    16981 caacaagaag gcttgttcgt ctctttgatg gatgcgcgtc gcaacaatgt ttatgcagga
    17041 ttttatgaaa atgctaaacc cgtcatgcca gaagctcact taccctttga gcgagtgatt
    17101 gagttaatca agggtgctag tcaggttacc tttgtcggag aagttggccc ctttgttgag
    17161 cagattcaaa aacacttgcc aaggactaat ttcaaagaaa ccttgcccaa tgcagctaat
    17221 ctagctctat gggcctggga caaggaagca gactccttgc atgattttgt gccgaactac
    17281 ctcaagcgtg tcgaagctga ggaaaactgg ctcaagaatc acaccgagtc tggcgagtct
    17341 tacattaaac gcttatgata gaaatcaaac gaatccaaca gcaacctgcc ttggctcaag
    17401 atatctacgc tgtcatggca gctgtttacc cagtcagtcc ttggacacta gaacaaatcc
    17461 aagcagatct gtcccaagac cagacttggt atgcattggc ttatgatggg gcagaagtga
    17521 ttggatttct agctgttcag gagactctct ttgaagcaga agtcctgcaa atcgctgtca
    17581 aaggagccta tcagggtcag ggaattgcgt cagccttgtt tgctcaattg ccgacagata
    17641 aggagatttt cctcgaagtc agaaagtcaa atcaacgagg gcaagcattt tacaagaaag
    17701 aaaagatggc agttatcgct gagcgaaagg cctactacca tgacccagtc gaggacgcca
    17761 ttatcatgaa gagagaaata gatgaaggat agatatattt tagcatttga gacatcctgt
    17821 gatgagacca gtgtcgccgt cttgaaaaac gacgatgagc tcttgtccaa tgtcattgct
    17881 agtcaaattg agagtcacaa acgttttggt ggcgtagtgc ccgaagtagc cagtcgtcac
    17941 catgtcgagg tcattacagc ctgtatcgag gaggcattgg cagaagcagg gattaccgaa
    18001 gaggacgtga cagctgttgc ggttacctac ggaccaggct tggtcggagc cttgctagtt
    18061 ggtttgtcag ctgccaaggc ctttgcttgg gctcacggac ttccactgat tcctgttaat
    18121 cacatggctg ggcacctcat ggcagctcag agtgtggagc ctttggagtt tcccttgcta
    18181 gcccttttag tcagtggtgg gcacacagag ttggtctatg tttctgaggc tggcgattac
    18241 aagattgttg gggagacacg agacgatgca gttggggagg cttatgacaa ggtcggtcgt
    18301 gtcatgggct tgacctatcc tgcaggtcgt gagattgacg agctggctca tcaggggcag
    18361 gatatttatg atttcccccg tgccatgatt aaggaagata atctggagtt ctccttctca
    18421 ggtttgaaat ctgcctttat caatcttcat cacaatgccg agcaaaaggg agaaagcctg
    18481 tctacagaag atttgtgtgc ttccttccaa gcagctgtct tggatattct catggctaaa
    18541 accaagaagg ctttggagaa atatcctgtt aaaaccctag ttgtggcagg tggtgtggca
    18601 gccaataaag gtctcagaga acgcctagca gccgaaatca cagatgtcaa ggttatcatc
    18661 ccccctctgc gactctgcgg agacaatgca ggtatgattg cctatgccag cgtcagcgag
    18721 tggaacaaag aaaacttcgc aggctgggac ctcaatgcca aaccaagtct tgcctttgat
    18781 accatggaat aaggagtggc tctttgtcaa gtgtagtggg taggcgaaaa gctacaatct
    18841 ggagagtacg aaattcgtac tctctttttt gatgttcaaa gtcatcaaaa tccgtttttt
    18901 aaaattgtta aagttccgga aaccaaaggc tttgcgcttg ataaccttaa tcaaattatt
    18961 ggtcgcttca agtttagcgt tggaataagg cagcttaagt gcgttgataa tcttatctct
    19021 atcccttaaa aaagtccaaa agaccgtttg aaaaagcgga tgaaccgttg gcagttcttg
    19081 ctcaatcaat ccaaagaaat ggtcggcatt cttctcttga aaatgaaaga gcaggagttg
    19141 atagagttcg tagtgaacct gtaatccctc agagtaagaa agcagcttat ctcgtacttc
    19201 ccgatgggtt aagtgcattc gaaacgtggg ctgatagaat cgtttctgac agagcttgaa
    19261 gctatcctgg tgtagtaaat cagtccagtg gactgattta gcccgagcct agaaacgaaa
    19321 aagcgagggt tccaaaagcg cttgagcgcc cgatactcca aggattttcg gtcaaattgg
    19381 ttcatgattt ggattcgtac tcggttcata gctcggctca gatgttggac aatgtggaag
    19441 cggtcaagaa caatcttcgc ctttggaaag agttgcttag cgagccgata ataagggctg
    19501 tacatgtcca tggtgatgac ctcgaccagc tcccgaacct ctctctgata gcgttggaaa
    19561 tggtttcgaa tcaccgcatg agttcgcccg tctaaaattg cgaggatgga tttggactca
    19621 aaatcttggg caatgaagct cattttgctc tttttgaagc tatactcatc ccaactcata
    19681 acttttggca acttggtcca atcggtttca aacttaaatt ccctcagttt tcggatgacg
    19741 gtggaagttg agaccgccaa tctgtgggca atctcagtca tagactgctt ttcaaggagg
    19801 agctgagcga ttttttgtct caccatgttg gaaatctggc aatttttctt gacaatggat
    19861 gtttgagaaa cgaccacctt aaggcaattc ttgcactgaa agcggcgctt tttgagatgc
    19921 agtaccgtgg gtaaaccctg acagtcgaga agcggaattt tagaggcttt ctggaagtcg
    19981 tatttgatca tcttcccttg acaatgagga caaggaggag cgggggaatc caactttgcc
    20041 tgaacgacta gatgggtttg gtatttcaga acagacaaga ttttgatatt tttgtcttcc
    20101 aatccgagca aatctgtggt attcttaagt tgttccatat ggaccctttc taatgagttg
    20161 gttagacgct tttcattata ggtcatatgg ggcttttttt ctacaagaaa cgaccctata
    20221 attcctgggg tgggattacc cactacagaa attatagagc ccaaacattc caaagtcttg
    20281 tctgactctg gaatgttttc tgttcacagt tgttttgtaa ctgcctaata agtaaccgcg
    20341 ctataacgag gtatctaccg agattgtcaa ttctccagta tactgttata aaaaacaaaa
    20401 ctggaggatt ttttatgtcc ccccatcgtc ccatcgactg ttccgtagct gcccaataac
    20461 ggagtatagt cggctgaaac aagaatagga caaaagtgcc tcaagaaaag catcgtaatt
    20521 tgacaatatt attctgagat gtttttgatg taagcccata ttttctcaat gggattatac
    20581 tcgggtgaat aggtaggaag tggtaacagt ctatgccctg ctccttacac atgttcattc
    20641 tgtgaaacct tgcattgtcc ataatgataa gggatggtgt atctaatgat aagggatggt
    20701 gtatctaaag taggtagtaa gaatttttgg aagcaagctt cgaaaaagtc actcgtcatc
    20761 gtatctttat aggtcatcgg agccatagta tattgaaaca aaaaagggca ttagtacttc
    20821 tataacagta tcgcaatctc tggtgtgcgt tgtctcgatc ttaattcaaa taattatatc
    20881 ttcttccaga gagactaact gcctgctcaa ggctcgatca tattcgagat aaaaataggt
    20941 cttaacccct gtctcataaa tataaatagg agtcaggtag cttaagtgat tcaattcttt
    21001 aaggaaccga tttacttttt ctgggtcttg ttcgcagtag gtacagctct tttttagact
    21061 atatcccata gcctttagag cgtaatgaat agttgttgga ggacagttga attcagcagc
    21121 tatttcagtc aaataagcat cgggatgagt ttcaatatag atctttaatt tatctctatc
    21181 aactttttca attaatagtg gaagttttct taaagttagt gtattgaaac gtttttatac
    21241 agtgctaaaa tttgaagtgt agtgcagata tatttgtaat agtattatag caattctttg
    21301 aagaaggtcg agacaagaga aaataggtat ctttgagata taagcatgat ttactataaa
    21361 attattgagt tattcataaa aatttctcta tcaaatatca taatgcgtcg tttaaggaga
    21421 tggttacaat gcaatatagt tgtggaaaaa taaatattaa tatccctgat ggatatggag
    21481 acattaagga tatagtgttt tcggctcata ttatagttag gtataataat ggacattgtg
    21541 gaggtataga tccgcatata attggacttt gtaaaaagca gatcagaagg atgtctctat
    21601 atcctatttt gataatcgta tctagagatt caaaggttat tgatgattat aaaaatttag
    21661 atattgccta tgttgattgt actcaatgtt caaataattt tgaaactgcc ttacacgtta
    21721 aaaatatttt aaaattatta aaaatccaac ttatacactg tcatggctac tcaactaatt
    21781 attttttata tatgttaaaa aaacttgaca agaatggatt tggaaaggtt aagacagtga
    21841 taacatgcca tggatgggtt gaatataact taaaaaagaa attcttgact tattttgatt
    21901 tttggacata ttctatggga gatgctttta tttgtgtatc tgaaactatg aaaaaaagat
    21961 tggagagtat aataaaaaat aagaagatag ttgcaataaa taacggaatt aatgtatcaa
    22021 atagcgattt agatgtagta ggtgttcaag actttaaaaa agaattttgt attccaaata
    22081 acaaaaaaat catttgttat gttggaaggc aagagaagaa aaaattttta acgaatttct
    22141 ttttttgaaa tacatgttat tatataattt tggttttttc tattgtatat atgacaacta
    22201 tgttcaatta aaatttagaa agtgagaaac tattgtgtat actattataa aatcaaatat
    22261 aaaaaaattt agtttattaa cgatatttat tgttgctggt caattattgc taatttatgc
    22321 agcaactatt aatgctctgg tgttgaatga attaattgcg atgaatttag agcggttttt
    22381 gaaattgtca atctaccaaa tgattgtctg gtgtgggata atattccttg actgggtagt
    22441 gaaaaattat caggttgaag tgatccaaga gtttaatcta gagattcgaa atagagttgc
    22501 cacagacatc tctaactcta cctatcaaga atttcatagt aaatcatcag gaacatatct
    22561 ttcgtggcta aataatgatg ttcagacttt aaatgatcag gcttttaaac aacttttttt
    22621 agtaataaaa ggaatttctg gtactatatt tgcagttgtg actcttaatc actatcattg
    22681 gtcattgact gtagccacct tgttttcatt aatgattatg ctacttgtac caaaaatctt
    22741 tgcatcgaaa atgcgagaag ttagtctaaa tttaactaac caaaatgaag cttttttaaa
    22801 atctagtgag actatattga atggatttga tgtgttagcg tccttgaatc ttttatatgt
    22861 attgcctaag aaaattaaag aagcaggaat tttattaaag atggttatac aaagaaagac
    22921 aactgtagaa acgttagcag gcgctattag cttctttctc aatatttttt ttcagatatc
    22981 tctcgttttt ttaacaggct atcttgcaat aaaaggaata gtgaaaattg gtactattga
    23041 agcaatagga gcactaacag gtgttatttt tacagcgcta ggtgaattag gaggtcaatt
    23101 atcctctatt attggtacga agcctatttt tttaaaattg tattcaatta atccaattga
    23161 gtcaaataaa atgaatgata tcgaaccaaa tgaggtgaat agagattttc cgttatatga
    23221 agcaaaaaat atttgctata agtatggaga taaagaaata ttaaaaaact taaatttttg
    23281 ttttcaacgt aatgaaaagt atttaatttt aggtgaaagt ggaagcggga aatctacatt
    23341 attaaaatta ttgaatggct ttttgagaga ttatagtgga gaattgcgat tctgcgggga
    23401 tgatataaaa aaaacctcct atttaaatat ggtttcgaat gttctatatg tagatcaaaa
    23461 agcttatttg tttgaaggta cgattagaga taatatttta ttggaagaaa attatactga
    23521 tgaagaaata ctacagtctt tagagcaagt tggtttgagt gtaaaagatt ttcctaataa
    23581 cattttagat tattatgttg gtgatgatgg gagattactg tcaggagggc agaaacaaaa
    23641 aattacttta gctagagggc taattagaaa taagaaaata gtattaattg acgagggaac
    23701 ttctgctatc gataggagaa cttcgttagc gattgaacgt aagatattag atagagagga
    23761 tttgactgtc attattgtta cccatgctcc gcatccggaa cttaaacaat attttactaa
    23821 gatatatcaa tttccaaagg attttattta agaatatagg ggagggaaac atgagattct
    23881 attgtgaagc ttatgaggta attactgaag agaaaaaagt atcatttttt tatgtagatg
    23941 aaaaaccctt aaggtatctg ttatttgact atatatttct actagttcta gctaaaaaaa
    24001 atatcccaat cttatgaact gcaccccaaa agttagattt attctgtcta acttttgggg
    24061 tgcagttcat tttgcatagt tttggcattc atcctagata tccatataaa atgtctgaga
    24121 ttgttgaaat gtctaaaaaa atatcagatc taaacgataa aaaagaattt cacaaaaaga
    24181 actgtgagtt gaggtttcaa gatagtgttc ttgataacat aaatagtgtc ccgggtacaa
    24241 ctcatttatt tagttgttta aatattcaaa cattagtaaa aattatttta tatatttttc
    24301 gatacaacag ttgtatgaaa atatttaatt ttagagataa agagcttatc ttttttaata
    24361 agattgtaaa tgggctgata caaaatattg aggagaattt agaggatgat attgaaagga
    24421 tattgaaata tttatatat
//
LOCUS       DAVHSI010000031        24022 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.031, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000031 DAVHSI010000000
VERSION     DAVHSI010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24022
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.031"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1766)
                     /locus_tag="VVR21_001444"
     CDS             complement(<1..1766)
                     /locus_tag="VVR21_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEU6055306.1"
                     /translation="MFKVLRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGAVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNGTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGTQTAAATEATAKKVEEDRKKP
                     ASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTTVNGAPAINASLNIA
                     KSERKVYTGTGLDSVYNVPIYYQLTVTNDGLKLTFTYTVTYVDPKTKTLGNISKKMSN
                     GYSIYNTGTSIQTMLTLGSGLGKPSGVKNSITDKNGVLVQFYNISTMTKQGSGYTWAN
                     GAQMNGWQAKKGYGLTSSWTVSIIGTDTSFTFTPYAAKTDNIRINYFNGKGKVVESST
                     TSQSLSQSKSLSVSASQSASASASTSASASASTSASASASTSASASASTSASASASTS
                     ASASASISASESASTSASASASTSASESASTSASASASTSASESASTSASASASTSAS
                     ASASTSASASASTSASASASISASESASTSASASASTSASASASTSASASASTSASAS
                     ASTSASASASTSASASASTSASA"
     gene            complement(1764..1877)
                     /locus_tag="VVR21_001445"
                     /pseudo
     CDS             complement(1764..1877)
                     /locus_tag="VVR21_001445"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2119..2580)
                     /locus_tag="VVR21_001446"
     CDS             complement(2119..2580)
                     /locus_tag="VVR21_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055307.1"
                     /translation="MRKERREQGNLERKKRVVKKRKILLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2577..2687)
                     /locus_tag="VVR21_001447"
                     /pseudo
     CDS             complement(2577..2687)
                     /locus_tag="VVR21_001447"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2957..3337
                     /locus_tag="VVR21_001448"
     CDS             2957..3337
                     /locus_tag="VVR21_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU6055308.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEASLDFLI"
     gene            3436..3657
                     /locus_tag="VVR21_001449"
     CDS             3436..3657
                     /locus_tag="VVR21_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU6055309.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3674..3988
                     /gene="trxA"
                     /locus_tag="VVR21_001450"
     CDS             3674..3988
                     /gene="trxA"
                     /locus_tag="VVR21_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6055310.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4293..4826
                     /gene="queF"
                     /locus_tag="VVR21_001451"
     CDS             4293..4826
                     /gene="queF"
                     /locus_tag="VVR21_001451"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU6055311.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(5080..5748)
                     /locus_tag="VVR21_001452"
     CDS             complement(5080..5748)
                     /locus_tag="VVR21_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU6055312.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(5859..6650)
                     /locus_tag="VVR21_001453"
     CDS             complement(5859..6650)
                     /locus_tag="VVR21_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU6055313.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDGGLDKEIDKIGLPTLERSFRALIYATLLSDDANQ
                     QSIFYQRLKAEIRNVLLNQGLHYLSKEEDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            complement(6897..8693)
                     /gene="pepF"
                     /locus_tag="VVR21_001454"
     CDS             complement(6897..8693)
                     /gene="pepF"
                     /locus_tag="VVR21_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU6055314.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKTLTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(8704..9447)
                     /locus_tag="VVR21_001455"
     CDS             complement(8704..9447)
                     /locus_tag="VVR21_001455"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU6055315.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLLELEK"
     gene            complement(9449..10399)
                     /locus_tag="VVR21_001456"
     CDS             complement(9449..10399)
                     /locus_tag="VVR21_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU6055316.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            complement(10537..10965)
                     /locus_tag="VVR21_001457"
     CDS             complement(10537..10965)
                     /locus_tag="VVR21_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6055317.1"
                     /translation="MEIEISGFTGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECAAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFFSSSQVVPQLQERLKDYLKVSD"
     gene            complement(10967..12034)
                     /locus_tag="VVR21_001458"
     CDS             complement(10967..12034)
                     /locus_tag="VVR21_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU6055318.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVRKDVVQTHKAMKIARQKMDSSRMLR
                     DEKRYYENLLAELEKELAEGV"
     gene            complement(12053..12523)
                     /locus_tag="VVR21_001459"
     CDS             complement(12053..12523)
                     /locus_tag="VVR21_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU6055319.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKEGLEEGEFYPYPRY"
     gene            complement(12814..13266)
                     /locus_tag="VVR21_001460"
     CDS             complement(12814..13266)
                     /locus_tag="VVR21_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU6055320.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(13303..13482)
                     /locus_tag="VVR21_001461"
     CDS             complement(13303..13482)
                     /locus_tag="VVR21_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU6055321.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            complement(13619..13798)
                     /locus_tag="VVR21_001462"
     CDS             complement(13619..13798)
                     /locus_tag="VVR21_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055322.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(13963..14202)
                     /locus_tag="VVR21_001463"
     CDS             complement(13963..14202)
                     /locus_tag="VVR21_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055323.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            14472..15743
                     /locus_tag="VVR21_001464"
     CDS             14472..15743
                     /locus_tag="VVR21_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU6055324.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDKGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            16008..16080
                     /locus_tag="VVR21_001465"
     tRNA            16008..16080
                     /locus_tag="VVR21_001465"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16041..16043,aa:Lys,seq:ctt)
     gene            complement(16290..17609)
                     /locus_tag="VVR21_001466"
     CDS             complement(16290..17609)
                     /locus_tag="VVR21_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU6055325.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17619..18464)
                     /locus_tag="VVR21_001467"
     CDS             complement(17619..18464)
                     /locus_tag="VVR21_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6055326.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRFAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            complement(18466..19368)
                     /locus_tag="VVR21_001468"
     CDS             complement(18466..19368)
                     /locus_tag="VVR21_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6055327.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYTFTDYYLLTPDERKFVGFENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            complement(19464..20774)
                     /locus_tag="VVR21_001469"
     CDS             complement(19464..20774)
                     /locus_tag="VVR21_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU6055328.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(20901..21896)
                     /locus_tag="VVR21_001470"
     CDS             complement(20901..21896)
                     /locus_tag="VVR21_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6055329.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            complement(22258..23739)
                     /locus_tag="VVR21_001471"
     CDS             complement(22258..23739)
                     /locus_tag="VVR21_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6055330.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
BASE COUNT         7333 a         5161 c         4177 g         7351 t
ORIGIN      
        1 gccgacgcac tggttgacgc tgaagctgac gcactggtac ttgccgaagc cgacgcactg
       61 gttgacgctg aagccgacgc actggttgat gcggaagctg aggcgctggt gcttgctgag
      121 gctgacgcac tggttgacgc tgaagctgac gcactcgttg aggccgattc agacgctgag
      181 atacttgctg aagctgacgc actcgttgat gctgaggctg aggcactggt acttgctgaa
      241 gctgatgcac ttgtgcttgc tgaggctgac gcactggttg atgctgattc agacgctgag
      301 gtacttgctg aagctgacgc actggttgag gccgattcag acgctgaggt gcttgctgaa
      361 gctgacgcac tcgttgaggc cgattcagac gctgagatac ttgctgaagc tgacgcactc
      421 gttgatgctg aggctgaggc actggtactt gctgaagctg atgcacttgt gcttgctgag
      481 gctgacgcac tggttgatgc tgaagctgag gcgctggttg acgctgaggc tgaggcgctt
      541 tgactagcac ttactgatag tgacttagac tgtgaaagtg actgactggt cgtgctagat
      601 tcaactacct ttcctttacc attgaagtag ttaattctaa tgttatctgt tttagcagca
      661 taaggggtaa atgtaaagga tgtatccgtt ccaataattg atacagtcca agatgatgtt
      721 aatccatatc ctttcttagc ctgccaacca ttcatttggg caccatttgc ccaagtatac
      781 ccactaccct gcttcgtcat tgtagatata ttatagaatt gaaccagtac accatttttg
      841 tcagtaatgg agttctttac acctgaaggt ttaccaagac cactgccaag ggttaacatt
      901 gtttgtattg aagttcctgt attatagata gaatatccat tactcatctt ttttgatata
      961 ttaccaagag tctttgtttt aggatccaca tacgtaaccg tataggtaaa ggtcagtttt
     1021 aagccatcat ttgtcactgt caattgatag taaattggaa cattatatac cgaatctaaa
     1081 cctgtacctg tataaacttt tctctcactt ttagcaatgt ttagacttgc attaattgca
     1141 ggggcgccat ttacagtcgt attgccagaa aaaacagcag cttttataga agccagcaat
     1201 tgctcgatgg aatccactga acgcttgcgt cgcttagcat aagattggag attgacattt
     1261 gtaactgatg ctacataatc actagctggt ttcttacgat cttcttcgac cttcttagca
     1321 gttgcttctg tagcggcagc tgtttgtgtt cctaccacag tagatgatgc agagatactt
     1381 gtcgaagccg atgtacttgc tgattctgat gcacttgtac tcgctgaggt cgaagcgctg
     1441 gttgaggctg actcagatgc agatgtactt gccgactctg aagctgacaa actagttgaa
     1501 ctcgctgaat tacttgtaga tatcgtacct agaactactg taccatttgt tgccaaagca
     1561 tccgttttct ctacagtttt ttcaagtact gctgactcat ttgtaaatac cttcgtttga
     1621 gttgcaacgg ttccactgat gacagctccc gcagcaacta tccccttgag gatatcaagc
     1681 ccagtaattg aatgacttac tttatcttct accgtttcgg tcatgacctg agtagtatca
     1741 acaccacctc gcaagacctt aaacaagcca aaaagagaag tcgaggcccg tagccaatgc
     1801 ttccctgatt tgattaattt gaaccgagtt actcggtctg tttctctata ttcactcttc
     1861 tgacgtctaa aaaatatttt gaaatttcct ttcgagtatt attttcatgt atggatataa
     1921 ataaattacc atactataat tatagaatag ggaacccaaa atagcaagaa acttgaggta
     1981 tttttgctaa aaaaaaaaag cattttacta ttttatatat atatatatta taagataagt
     2041 tttttataaa gacacgtaac tgagtataaa tcagctaatt tttggtttac atccctattt
     2101 ttatgcataa ttattctgtc attctctaat ttgtgaatca atatatctga ttagaaaact
     2161 accattgagt ttttgctcca cctcattagt ccgctcaaaa cgccgtccgc taatcttgtc
     2221 atagactttc tcccctctag gagcccctgc ataaggacga tagaggtagc ggttgattcc
     2281 cgtttcgtca atatatagga ctggtaaatc ttttaggtta tccaaaatat caagaaactc
     2341 agaaactttc tcaggctttt gttccctaaa actggtcgtc ttttttaaaa tgaccttaat
     2401 ctgctttaaa actgcccata cggagggcaa agcacaatca aaacgggccg caatttcccg
     2461 taaaaaagcg tctggatgag cctctacaaa ggctttcaat tcttctaaaa ggatcttacg
     2521 ctttttgacg actcgctttt tccgctctaa gttcccttgt tcacgtcttt cttttctcac
     2581 gtgaagagag ttctgacgcc aacaccaaaa accttggccg cctcgacatg tctgtgccct
     2641 cctttgatgg aatctaatga tccttgttta aaatcagtac tatatgcata gctttattag
     2701 accatgctta ttttaaacta agcaactata gatagagaaa tgaaataaaa tctgaattcg
     2761 aatgcgataa ggagttagaa attgaaacaa taggatttcc ccattattca cacaaaaata
     2821 aaaccactaa aaaacagagc ttgccagtat tcttgaaaag tagtataatt attgcatgcg
     2881 caatcatctt gtgacgcaga gactgcccgt taatggactt tcttctattt atgactctaa
     2941 aaagaaagga gacactatga cctatttgga aaaatggttt gacttcaatc ggcgtcagaa
     3001 agaaattgaa agtctcttgg aagagaccat tgcccaacag agcgagcaaa gtctgacctt
     3061 gaaagagttc tacctgctct actatctgga cttggctgaa gaaaaatctc tacgccagat
     3121 tgacctgcca gataagcttc atctgagccc gagcgcagtt tctaggatgg tggctcgctt
     3181 ggaagctaaa aattgcggtc tactcagtcg catgtgttgc catcaagata gacgctctag
     3241 ttttatctgc ctgacaaatg atgggcaaaa gacactggcc tcgctacaaa agactgtcga
     3301 agaaagcttg gaagcaagtt tggatttctt gatttaagat gattttaaaa aaagttgcgt
     3361 gcgcaatcat ttttcttgac attctctttt ataaggagta aaataaagtt agcattaaac
     3421 aaaggagttt taaatatgat tgaaattacc tatatagatg ccagcaagaa cgaaagaact
     3481 gtgactttcg agtcttatga agactttgaa cgttcgcaac aagcttgcct tatcggcgtc
     3541 gcagactact accctgtcca aaaattaact tacaagggtc ataatttgga ctaccatggg
     3601 acttatggag atatcttctt ctatctcatg aaacaagatt taagccaata taactaaaaa
     3661 aaggagaaat acaatggcaa aagcaattac agatgcaaca ttcgaacaag aaacaaaaga
     3721 cggtttggtc ttagtagact tctgggcaac ttggtgtggt ccatgtcgta tgcaaggtcc
     3781 aatcttggac aaattgtctg aagaactttc agaagatgtc ttgaaaatcg ttaaaatgga
     3841 cgttgatgaa aatccaaaca cagctcgtgc ttttggaatc atgtctattc caactcttct
     3901 cttcaaaaaa gacggccaag ttgtcaaaca agttgcaggt gttcacacag cagaacaaat
     3961 caaggccatc attgctgaat tgagctaatc aaacgagaga ccaagtactt tctttggtct
     4021 cttttttctt gctctttgcc atttttcaaa aaatatgcta gactatagta gattgaaact
     4081 agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg tcctgatcga
     4141 tttgtcctgt tcttatttca ttttactata taagtagaat attacgatgt ttgggatatg
     4201 ccatcgctaa aaaaactcga tttggtattt tttagctccc taatgggagc tttttgcgtg
     4261 ctctgaacat ttcccatttt ggaaggagta ctatgaaacg tcaatcagcc ttggtcgtct
     4321 ttagtggtgg tcaagattca acaacctgcc ttttctgggc catgcaacac tatgaaacag
     4381 tcgaagctgt cacctttgcc tacggccaac gtcatcacct cgaaattcaa attactagag
     4441 aaatcgctaa ggaacagggc attcgtcacc atatcctcga tatgtctctg ctgggacaaa
     4501 tcactgctca gccagacttt gcgacgattc atatttccta cattcctgac aagctctgtg
     4561 tcgagtcaaa atccctcaaa ctatatctat ttagctaccg aaatcacgga gatttccacg
     4621 aaaactgtat caacaccatc gggaaagact tggtcaactt gctagaccct cgctatttag
     4681 aagtctgggg aaaattcact ccgcgcggtg gcatttcaat cgacccctac tataactacg
     4741 gtaagcaagg aactaagtat gagggcttgg cagaacaacg cctcttccaa cacgaccttt
     4801 atccagagaa aattgacaac cgctaaagtc atactcaatg aaaatcaaag agcaaactag
     4861 gaagttagcc gcaggttact caaagcagtg tttgaggtgg cagatagaac tgacgaagtc
     4921 agcttaaaac actgttttga ggttgcagat agaactaacg aagtcagtaa ccatacctag
     4981 gacaaggtga agctgacgtg gtttgaagag attttcgaag agtatcatac gaaaaagccc
     5041 tgttcctcaa gatgaggagc aaggcttttt gagtttcaat tattcttctg ttccaaggaa
     5101 attttttgca acaagggctg caagaactcc accagcgatt ggtgcaagga tgaaaatcca
     5161 aacttgttga agggctgcgc cgcctaccaa gacagctggt gccaagctac gagctgggtt
     5221 tactgaaagt ccagtaatct tcaatccgac aagaatcatc gccatcaatg acaaaccgat
     5281 taccaaacca gcaatcgcgc cattgccctt actttctgaa gtcacagtca tgataactaa
     5341 gacaaacaag aaagttgcga tgacttcaaa caagaaacca ccaaagacag tgactccgtt
     5401 tgccaaggca ttttcaccaa gactagcagt tgacatacct gaattaccca agaggaagaa
     5461 gactgcgcca gaagcgatga aagctccaac aacctgacca aggatgtagt ttacaagttc
     5521 tgaagatgac aaacgtttgt ttacaaacat agcaatcgaa acagccggat tcaagtgagc
     5581 acctgaaaca gttccgattg agtaggctgc caccacgatt gccaaaccaa aggcaaaggc
     5641 gattccaagg tgaccaaggc catcaagacc atttccaaaa acaacagctc ctgtcccgac
     5701 gaatacaagc atgaacgtac cgattaactc agcaacaaat tttttcattt tctttctcct
     5761 tttttcaaaa actagatact agtctatcaa aagtaggaaa gggtttcaag aaaattgatt
     5821 ggaaattttt tgaaaatcat agaactatta acttatccct agtattgaaa agactggata
     5881 gcttctttca ggtcatcttg taaactattt ctctggtcaa gttggacata gacttccaac
     5941 agacaggttc tgaagttgga aaatttgtaa aaatcctccc tttcttctat cggaaaatca
     6001 acagttttta tccaagaagc tacttgttct tgcgctaact tcccttgtaa aataggttca
     6061 tagatcactc ttgctaaacg ccaatcctca tcatctgtaa agcgaatcga cattctttta
     6121 aatagttggc caagtatatc aaatacttca tgaactctgt ttttaggaaa gtctggatga
     6181 caaaccacct ctgtcagtaa atcggctcca tgtgcaaaag aatgaaccca accatactga
     6241 cttgagaaac ctgttgtatc ctcttctttt gaaagatagt gcaagccttg atttaaaagg
     6301 acattacgaa tttctgcttt tagtctctga tagaaaatcg attgctggtt ggcatcgtca
     6361 gacaagagag ttgcataaat aagcgcccta aaagaacgtt caagtgttgg caggcctatc
     6421 ttatcaatct ctttatctaa ccctccatca gatgaaaccc cttcagcaat gaaatgaaat
     6481 tgctcctgtg taaatagctc ttcctgaatc cctctagcaa agcttgtaaa aacaaggtca
     6541 tcgcgaattt ctggagaagg atctcccaaa tgatcaagca accactggat ttcctcctgg
     6601 ttataatttg gtttttcttc tgctattttt cttagtaaat cttgatacat ggtcaatacc
     6661 tctacatttc tagcaactgt tcaaaaaggc agtcttaaat gactcaatat tgaattctca
     6721 attaaataca atctgatata aaatgacgta aataactatc aataccagtt ctacagtaag
     6781 ttcaaattta acatcacgac cttcaacgac atttttgaaa atagctacaa ctaagacaaa
     6841 tagaatgacg cttaacaagc ccataaacat cattctaaaa aatttttcta ttccccttac
     6901 tcccccaact cagcactgta ggcgataatc tggtcaactg tgtcagacaa gaattggatg
     6961 gtatcacgga gtggtttgtc tgttgaaata tcagcaccga taatcatggc tgactcaagt
     7021 ggtgtcttgc taccacctga tttgaggaga ttgagccagt cttcagctcc agtttctgaa
     7081 tttttaagat gaaggtaacc agcagtcgag ataactagtc ctgctgagta agtgtaacta
     7141 tacaagccca tatagtagtg agcttggcgc atccaagtca aagctgcatc gtcgtcgatt
     7201 tcaatggcat cgccccaaaa atctgtcaaa acttccttca taatactgtt gagtttgctt
     7261 gctccgaagg tttctccttc ttcaatcaat gtatacacct tacgctggaa ggcggcttcc
     7321 aagaggtggg tgatgaaatt atggaagtag gtgtctgtca agcgatgagc cagagcgaag
     7381 cgtttttgac gtgggtcatt agactggttc tctaagtaat cactgagtag caattcattg
     7441 aaggttgacg gtgcttcaac ataataggtc gacatgtggg cgttgaaata gctttgatga
     7501 ttgtctgaaa agatgaattg accagaatgc ccgatttcat gaatcaaggt atagacatcg
     7561 ctcaaacggc ctgtccagct catgagtaca taagggtgta cgcgatatgg gtccgccgca
     7621 taaccaccgg aatccttgcc actgttagca gcaaagtcca cccagcgctc ttcttggtaa
     7681 cgagcaactt cctgacaata ttcttgcccc aaaggttcta ccgacttcat gaccaaatca
     7741 taggcatcgt caatagtcac ttcaggattc agggcgctgt ccaagtccaa tttccagtct
     7801 gcaaaggtca tcttttcaag accatttacc ttggcaacat gcttgaggta tctctgagcg
     7861 actggtgcaa agtccttcat gatgaggtca atctggcggt caaacatgac acggtccact
     7921 tcttgttcag ctagaagata gtcaaagaca gagtcgtatc ccttcatatc agccaagagt
     7981 ttttcagact tgacctgagc cagataggct gctgcagccg tattttggtg cttacgaagt
     8041 ccctctgaga aggaacggaa ggatttctca cgaacctcag catcctcatg gttttggtag
     8101 aaattctcat aggtcacaaa gctgttttta taggtcttgc catgggcttc aaagtcagcc
     8161 atttcaaaat ccccagctcg catcttagta taaatgtcct gcggactata gaaaacttca
     8221 ccgagattgg tcaaggtctt ctccacatct gcccctaagt agtgggcttt tttgatttta
     8281 gcctgacgaa tggcagctgt taaatgtggc aatttaccca aacggtccaa gacttcctcg
     8341 tctgctgcca ccaaggcatc gtcaaagaag gtcaaggcta cgctggcatc tgtttcaaat
     8401 tccatcccag cttgagcaat atttgcaaat tcgtcattgc tatagtccgt cgtctgaggc
     8461 ataaaaccat agttgccaat atggctcatc tgaatgtaga tctgttccaa ttccgcaaag
     8521 gccttctcga aatcctcaaa agtgtgaaga ttgcccttgt aatcacggct aaactggttg
     8581 atgtcttcgc gagctttctc gattgcacgc aagaaatcct cacggtcttg gtatagagct
     8641 gttaaatccc aaagttcctt ctctggaaat tctgaacggt gtttttgttc cattttcttc
     8701 ctcttatttc tctaattcta ataaaacact aagggctgat aaagcgtaaa gcggtgctgt
     8761 ttctgctctt agaatgcgag ggccaagtcc tgccaaaaca gctcccttag cttcaaaatt
     8821 ttcaatttcc gcaggtgaca gaccaccttc tggaccaaag ataaagagca atttggctcc
     8881 tttctcgagt ccagtaactg cttttataag agcagcggct tctccttctt tggccgcctc
     8941 ttcataggct actaagatgc ggtcaaactg gtcaagttgg gctagaaagt ctgctttatt
     9001 ctcgaaaaga tggatacttg gaacaatatt acgcttgctt tgctcggctg ctccaagggc
     9061 aattttttct agtttttcaa cttttttacc caatttcttg ccatcccact tggcaactga
     9121 ccagtctgca ggaaaggccc agatttggct agcacccagt tcggttactt tttgagcgat
     9181 gaactccagc ttgtctccct tgggaaatcc agatgcgatg gtcacttgga ctggtagttc
     9241 cacattgtca tttaattctt ggaccaactc aaactgacga ttttccatat ccagcacgcg
     9301 cgccaagcgc ttgatgccat catcaaagac taaggtaacc tcatcctctt ctttcaagcg
     9361 cataacctga aacatatgct tactggtttc cttgtcctcg atagtgacag gagagatagc
     9421 actgcctttt acaaaatact gctgcatgct agcctccaat cacaccagag atatccttgg
     9481 ttttcttaaa gacacaggta ttccattccc cttgaaccat gtgagtttcg aggaaaaatc
     9541 cagctgattc agccaactcg cgcaccatgt cccacttatc cttgataatg ccactcatga
     9601 tcaggtaacc ttcatcctta accaagcgat aagcatcctc tgtcagatga atgaggatat
     9661 ccgccaagat gtttgccacg atgacatctg cttcaatctc cacgccttta agcaaatcgc
     9721 ctgccgctac atggatattt tccattccag ggttgagctc aatattttcc tgagccacac
     9781 gaactgccac atcatccagg tcataggcga aaatttcttt agcccccaga agcgagctgg
     9841 caatagagag aacccctgaa ccagttccca catctagcac cgtttcgcca ccacgaagaa
     9901 cctgttccaa ggcaaagagg ctcatcttgg tagttgggtg ggttcccgta ccaaaagcca
     9961 tgccaggatc cagcttgata attttttctc ccgcagtcgc ctcatagtct gtccaagagg
    10021 gaacgatggt caaatcatga gtgatacgag ctggctcata gtatttcttc cagttatctg
    10081 cccagtcttc ctcagccaag gcagtcgtac ctatttttaa ctctcccaaa tccataaaat
    10141 ccgtcaattc tgatatgcga gcctgcaagt ccgcctcaac cactgtcaca tccaccgtgt
    10201 cagggtagta ggctgtcact acgatttctt cttgctgctc cacctctggg aaaatctcgc
    10261 caaaacgatc cacatttccc atatagtcca tgctgtcttc aatcgcgact ccttgcgctc
    10321 ccagctcaat caagagattg gaaaccaact cctctccctc acgcttcact gtaactttta
    10381 actcttgcca tgtttccatt attaagatac caagcccgta aaatacaaaa ccaaaatagg
    10441 aaattctctg aagacgcttg tgtctaagag aagtttatct ttttggcaca gtgtttaggg
    10501 cgggttcagt ttagaaattt aactgaacca tcctttctaa tcacttactt ttaaataatc
    10561 ttttaatctc tcttgcaact gagggacaac ttgactggaa ctaaaaaatt cctcaacatt
    10621 catcagctga tagccctgtc cttcatctcc aaatacgata ctgtcaaact ggttctgtgt
    10681 caactgacca actagaaata cagattgttt atccgcaaaa agcatacttg gataaacctt
    10741 actccaaagc agacaatctt cagtcagatg aatgcccagt tcttcataaa cttcacgcgc
    10801 cgcgcactca aaaggacttt catcaccttc acgtccacca cctggcaact cccacatgtt
    10861 gggacaaggg atatcgtcct tgtcatcacg caaaatcgtc agtagcttat ccccacaaaa
    10921 gagggcaatc ttgcaacctg tgaaaccaga aatctctatt tccatattag actccttcgg
    10981 ctaattcctt ttccagctct gctaacaagt tttcataata gcgtttctcg tccctcaaca
    11041 ttcgactact atccattttc tgtctagcaa tcttcatagc cttgtgagtt tgaaccacat
    11101 ctttccttac cttaaattga taccaagctt gtatcacttg aagattggac agtttgagag
    11161 acagaaacga tttgacctgt cgaatactag catattgctc cgcttgctca aaatctcctt
    11221 ccaacaaggc gatatgaagt agggatagtt gggcaactgt ctgcatcatc ggagtagttg
    11281 tcctctcaag taatgcttga aactgctgtt tagctacttc ttccttccct tccaaaatgg
    11341 aaacttcacc ttgcatacct aatacaccat ccgcaaaact ccctcgtgca tcctcaggaa
    11401 ctgcttgaac aaagtctttc aaatcatatt cttgaggagc cagcaaagtt tgagcagaat
    11461 gtctcaatac caggtaggcg tatttggtat tttcagggtg ttgtagtaat tcccaaattt
    11521 ttgctccatc ggtgatgtcg actggcaaaa tgttatttag gaagaaagat aaattaagaa
    11581 aaatccaagt ccctgcaaaa taccagcttc ttgtcaaaaa tccaaacact atcgccaata
    11641 atatcaagcc gagatgaacc atcaagcctc ctgaaagcat caggatgatt ctttgatcgc
    11701 tttcatcctc ttttaaacca atgtattgag caccaacatt tttcagaatg gctgttctac
    11761 taagatgaaa cctgcctgac tttttggtca aaataaaatg tcctaatcca aaagccacca
    11821 gccgatagcc tgtcaagtag ccacaaaaag catgacccag ctcatgaaga ataaagatta
    11881 aatacatgct tagaagagcg aaggcataac caaaagtaaa ggctaaaact gcggaatacc
    11941 ccaactctgc aaatgcgatt gttccacaag caaaagctag cataataaag acaacagcta
    12001 gcacataaac caaataagtc ccaattttct tcataacacc gccaaccaac tcctagtatc
    12061 ttggataagg gtaaaattct ccctcttcca agccctcttt tccttcttca aagacttctt
    12121 ggttccattc catgataaat tcctctgctt ctgggtcttc caaaaagtcc atgaggacat
    12181 ctagcccaac ctcagcagta tctttaagga aaagcgcaaa ataagctaaa aattcacggg
    12241 aaaatccttt tttaggcagg taaggaataa cagtcaaata gtcttcctca ttgactgttg
    12301 acttggcagg attgtagaaa aggaccgctt cctcaaaaag aatgtcatct gatgaaacct
    12361 ctccgtcttc atccaccatc tccacacctg cagcattttg cgcttccaat agaaaactca
    12421 cttctaccgc atggttgcgt ttgtcccagc taatctcaaa gtcaaaggga aagttcttgt
    12481 ccaactcttc ctctaaaaca tctaaaaatc cgtatgttgc cattttgtcc tctttctatg
    12541 cgactcttta atcgccccga ttgctcggaa atatgctaaa atagatacta ccatcttacc
    12601 acaaaattat tttatgtcct aattatacca tattacctca tttaaaccct tggtatcagt
    12661 gattttctta aaagtctgat ttcttcattt ctcataaaaa tcaatataaa aagccctcga
    12721 aagggctaat aaatctataa aatcaatagg cgagtaacta gcacaagtgg acgtgctttt
    12781 ttattgacta ttaccacgat accacgctta atcttaggct tgaactttct tatctgcaat
    12841 agcgtctgtc aaagtctgag aaaagttaag tcccatttct cgtcccaact tatctgccca
    12901 ttttggtatg gtcaaagtct ttttaatggg ttcctgactt cctaggtatt ctgatacatc
    12961 aacagatacc atagaaataa aagatttatc aaggtcatag gttgacacga aatcttcatc
    13021 atctttaaaa ggatcattat caattaaaga caagctattg atatctgatg gctgaggtaa
    13081 ctctccatca ctctctatca aatctgcaac agttatccct agccactccg accccatagc
    13141 caaagcctca gaaatcccct ctccttgtgt agctgagtat tcaaaatctg ggaaatggac
    13201 aaaataagtc gcttctgttc cgtctgtgtc atcataataa aataaagctg gatacgtaac
    13261 taacatttca ctacctccat atcaaaaagc aggggctgaa ttttacaacc cagcttgctt
    13321 tcttatccct ctttcagtgt acttattcag ctcaccatga aggattgtga taggtctttc
    13381 cccttgcttc tcgattttaa tatgggagcc tttaccgcct ctagtcttta tccaaccatg
    13441 ggccgtaagg agtttaacca tctctttttg tgtcataggt atagcgcttt tacctcctga
    13501 caacaccatt ataacacgtg ttacacgtat tgtaaaggag tgatacttat tattctatta
    13561 tacataaaag cccctagatg tggttctaag ggaaaccaat ttattcagac ctatttttct
    13621 aatgagtagt aaaaactgct tctttatcga gcaattcatc atctgtatag tcaattgtaa
    13681 aagtatctcg atctaagaca gattgaggcg gagttgaatg aatcatagga acactgcgta
    13741 ctctatattt tttatctcca atttttacaa actgatactc ttcgaaaatc aaattcaaac
    13801 cacgtcaacg tcgccttacc gtactcaagt acagcctgcg gctagtttcc tagtttgctc
    13861 tttgattttc attgagtatg attaactctc aagtcttcga aatcaggatt ttcaacagtt
    13921 attacaagga ggcgatttac tacttcaaaa acatcaatta ttctattttt catatttttt
    13981 caacccatta ttagaatgaa cttcttggta agcaaaatca agtttagatt taatgttttc
    14041 gtacaaatct aaaatctctt ttggagtatc ttcccggaag aaaagttttc ttttccctga
    14101 aataacttga tcactaagaa tccaatgacg aatttgtttt gtaaaaatca aaatttcctg
    14161 acttggtcca tcatttccat tgcttatcac ctctcttttc attatagttc atacaatgac
    14221 atttagcaat attatttctc aagtcagcac ttccacttct ttaggctcaa ctatcctatt
    14281 ttgagcttta aggaaaatca aatctctcat gctgatacct ctcctcatta aattaaatag
    14341 taaaaaagat tctatctcac tccctgatta ttacaaaacc attgaaatat cacaactaat
    14401 aggctagaat ggacatagta agatatagta gatgagtcat tctactcaaa tccacgttag
    14461 aaaggactgc tatgccagac aatctcgcgc ttcgcatgcg ccctaaaacc atcgaccagg
    14521 tcatcggtca ggagcatctg gtcggacctg gaaaaatcat ccgccgcatg gtggaagcca
    14581 accgcctgtc ctccatgatt ctatatggcc ctccgggaat cggcaaaacc agtattgcct
    14641 ctgccatcgc tggaacgacc aagtatgcct ttcgaacttt caatgcgaca gttgatagta
    14701 aaaagcgact gcaagaaatc tcggaagaag ctaaattttc tggtggtctc gtcctattgc
    14761 tagacgaaat tcatcgacta gataagacca agcaagactt cctcttgcct ctcttggaaa
    14821 gtggactggt catcatgatt ggagcaacga ctgaaaatcc tttcttctct gtcactcctg
    14881 ccattcgtag ccgtgttcaa attttcgagt tggaacctct gtctaaccaa gacgtcaaag
    14941 aggccctgca gatagctcta agtaaccctg aacgtggttt tgattttcca atagaactag
    15001 atgaggatgc gctggatttc atcgcaacct ctacaaacgg agaccttcgc tctgccttta
    15061 actcactgga cttggctgtt ctctctaccc ctgagaatga caagggcatt cgccacatca
    15121 ccttagacat catggaaaat agtcttcaga gaagctacat cactatggac aaggatggag
    15181 acggtcacta tgatgttcta tctgccctgc aaaagtctat ccgtggctca gatgtggatg
    15241 ccagtctcca ctatactgcc cgcttgattg aggctgggga tctgcctagt ctcgctcgtc
    15301 gcttgactgt tatcgcctat gaagatatcg gcttagccaa tcctgaggcc cagattcata
    15361 ccgtgactgc tctggatgcc gcccagaaga ttgggttccc agaagcccgc attctcattg
    15421 ccaatgtcgt gattgatttg gccctttctc caaaatccaa ctcagcctat gtagctatgg
    15481 ataaggcact tgctgacctc aaaacatcag ggcacttgcc tattccgcga cacctacgtg
    15541 atgggcacta cagtggaagc aaggaactgg ggaatgccca agactatctc tatccacaca
    15601 actatcctgg aaattgggtc aagcaagact atctgccaga aaaaattcgt aatcatcact
    15661 atttccaagc agaagatact ggtaaatatg aacgggcttt ggctcaaaga aaggaagcta
    15721 tcgaccgttt gcgaaaaatc tgaaatcctt ttcaaaaaat tgcactttcc tcttgatttt
    15781 ttttgaaaaa gtggtatcat ataaatatag aaacgctgtg gtgtacgact tcacacttaa
    15841 gtgttgaccg actatttttt gtattattag ggaaacaaaa gtcttctaac agcatgtagg
    15901 ccgtctcaca cggaaacagc ttcagttaga gcgagttgcc cacctgctta attgcgcggg
    15961 ttcaatacaa accgtgaagt ttcggcacca atacagcttt tttctttgcc tccttagctc
    16021 agctggcaga gcagcggact cttaatccgt gggtcacagg ttcgatccct gtagggggca
    16081 tctaaataca acaggaaaag tcttataata tagggctttt tttgcttaaa taaaattttt
    16141 ttcaaattct ttagaaaact agtttaaatc ataatccaac accaatttta caaataccat
    16201 aaactaagct tatataccca aaacacaaaa agtcctcttt ccactatttt agaaagagaa
    16261 ctttttcttt aggagaaata acttaatttt taatcaattc gtgatagctc agctggcacc
    16321 gttaagtaat aagttgcagt caagcttgct tcaccttgat tgacaaaaat ctcgatggaa
    16381 tttttatcta gaacaacttc caattcttta gcttcaatat ctacataccg tcgactagtg
    16441 tcctgttctt cttcacctag aattttttga ataagatggc tacgatcaat gtaaacttgc
    16501 tgcacattac tgtcataacc aaattcaaga taatctgtat catttcctaa gtggtaatga
    16561 caatctttat ctatttggat ttgatattgg ccttttttaa cagggaattg tcttagtttg
    16621 ccatcttcca atcttagaat tctaggtaaa gtcatggcac atgcccactt gtgttcttgg
    16681 tcatgggttg gaagggtacg cccccatgtc tgcatccaag caatcaggat acgacgattt
    16741 tgatcgtcca acaatgtttg aggcgcatag aagtcttggc catgatcaat ttcttgaact
    16801 gattctggga taaaacgttt ttctccccaa tctaccttac ccgtgaacaa aagcgatgag
    16861 ttgatgttat gatatgagtc tccctcacgc tgataacgca tgggtgacat aataaggcaa
    16921 tctttcccat ctaactcgaa gtaatctggg cattcccaca taaagccttg gtgttctacc
    16981 ccttttaaaa agatggattc gaactgccat tctactaggt tatcggaccc tagtagaacg
    17041 atacagccca cattattctt gtgtttggca gctactacgg agtaatagcg tccatctttt
    17101 tcaaagagtt ttggatcacg gaaatcagca gcaatcaact catctggcaa gtctgatcca
    17161 gttgcaactg gattttggga aatcttttca aagtgaatcc cgtcatctga aaatgccata
    17221 ttttgcactt ggcggacacc ggttttttct tcgatatgcc cagtgtacat gagccagagg
    17281 cgatcatcct tgacaatggc agagcctgag aaacaaccat ttcggtcata atcttggtca
    17341 ggagcaagtg ccactggcaa atgctcccaa gtcaccaagt ccttactttt agcatgtccc
    17401 cagtgcatag gcccccaaac actatcatat ggatagaatt gataaaagag atggtattct
    17461 ccacgaaaat agacaaatcc atttggatca ttgatccaac caatctcagc tgaaaaatgt
    17521 tcttcaggct tatattgagt attaacgaga tgtttatttt ctgctataaa acgattggct
    17581 ttttctactg taaatgtttt atttatcata agtatatcct attttattcc agttccggaa
    17641 ccacccagac cttgaacaat atatttctga gcgactacat agaccaaaat caacggaatc
    17701 gttgaaatag ttaatacagc cattacctga ttgatataaa ctggttgagt tgtattaata
    17761 gttgtaattg caacctgcat tgaaaattta gaagaatctg tcaaaaccat caatggccag
    17821 atataatcat tccagcttga aataaatgat aaaacaccaa ctgtagcaac tgcaggttta
    17881 gacattggaa gcataattct aaagaaaatt ctaacgatac ttgctccgtc catctttgca
    17941 gactcaagaa tctcttctgg aattgcaata aagaaattcc taaataagta aatattaaat
    18001 acactcgcca atcctggaat aataactgca aaacgattat tgaccaaacc taaggaattg
    18061 ataatggtaa attgtggaat taacacagtt tccactggaa taataagtaa agcaagtaag
    18121 aaaccaaata aaattttctt acctgaaaaa ttgacttttg caaaagcgaa accggccagt
    18181 gcattgacaa taatagaacc aatagcaaac gttccagcat aaaaaatgct gttccctaga
    18241 tatgtaaaaa tactaaagcg ctcaaatact tcctgataag gtttaaacca atcagcggga
    18301 tttaaacttg gtaagaaggc ttgccaacta gtcaaatttt tataaacatc cgcttctggc
    18361 ttcatagctg aaactaccat ccaaaccata ggaaaaagga agagtcctgc caataaagtt
    18421 aacagaatat attctaagat tgttgttggt ttaaatcgtt tcatcttagt catcctcctt
    18481 cagaacgcga cgttgtacta agctaatcat accaattaac gttgtaaata ctaaagcgat
    18541 tgagctagaa tatcctacaa gacgatcagt aaaaccttgt tgataaatat agtacaccat
    18601 agtaattgtt gagtttaatg gcccaccttg cgtcataacc attggttgta caatcagctt
    18661 aaaagcagaa attaaagttg ttaacaatac aaacagggct gttggtttta gtaggggcat
    18721 cgtgatataa cgaaactgag cccattttga gaatccatct aattcagcag cttcatagac
    18781 atcttgtgga atattctgca ttcctcctaa aaataaaagc atctgataac ctgcaccctg
    18841 ccaagcagaa acaaaaacaa ttgcatacat agcttgttta ggactagtca agaaaggttg
    18901 agaagcaata cctaccttat ttaaaatagc atttaataag ccactatttg gatttaaaag
    18961 ataaagccaa agaatagaaa taactaccaa ggacatgaca actggagcaa aaaaagccac
    19021 tttaaaaaac atatttcctt ttcgcttttt attgacaatc aaagccattc ctaaggccgc
    19081 tcccaattga actggaataa tccaaacaac aaatttcaaa gtattcaaga agctctttaa
    19141 gaaaatcgga tcttttgtta atcgaataaa attctcaaat ccaacaaatt ttctttcatc
    19201 tggtgtcaac aaataataat ctgtaaaagt gtaataaatg accattccaa ctggaattac
    19261 taaaaagata cctaataaaa ttaaagctgg agctaaaaaa ctataaccta atatgttatc
    19321 ctttattttt tcacgtcttt ttgtatacac aacagtttct ttactcatat ccatctcctt
    19381 taatcatata tatcaaacta ggctattaac aagaaagggg aaggtagttc caaacatttt
    19441 ccttccacct tcttttttac agattatttg agtgactgat caatagcagt ttgcatttct
    19501 tttgtacgag tatccaagac tttttgcaca tttggatttt cttcataata gctaatatct
    19561 tgcattgctt gttgaaaagc tcgagaaacc tgaggatatg ctacaacaac tgggcgagca
    19621 tgagctgttt ttgaattttg ttccatcaag aaacgcattg gttcggatac tttatctttg
    19681 atattttcaa ttgtagattt acgaattgga aggaccgaat tccccaagct aataatttca
    19741 cttgattctg tatttgtagc aaatttaaca aattcagatg cggcctcttt tttatcagat
    19801 tttgtcgtca cagctaattg ccaactacct gaaggggata ctaatttttt cgtcttacta
    19861 gatactgggt aaggaaggat accaaaatca atatctttgt agtttgtatt catgtcagca
    19921 atcgtccaag aaccactcaa aagcattgga tactctcctg tttcaaaacc tttttcgact
    19981 ggactaacag ttgtatagcc ttcttttaca agattttgaa tgaattgaac tgcttctaca
    20041 ctctctttgg agttgaagta tccttctgcc tttgttccat cttcgtttac gacagaacca
    20101 ttatttgacc aaatcaacgg catataagca tatggcaaca tttcatcgtt tgaattaata
    20161 cgaaaatcaa ttgctggttt gttataatga tctttcaatt ttttagcaat cgtattaaat
    20221 tcgtcccatg tccatggctt ttctagcgtt ggaagctctg attccgcaat tccggcctct
    20281 ttgaacattt ttttattgta ataaacacca acattcgatt cagaaaatcc aaatgcatag
    20341 aatttcccat tataagttcc ctgttgttta atactgtcca aaacatcatc catattatta
    20401 tcttttagat aatcatctag cggagtaatt actttagatt ttgcataagc tgccgtattt
    20461 ggtccatcaa gggtaataac atctggaaga ctattagtcg taatagcagc attaaccttg
    20521 tcttcatatc ctccaccact accactacga ggaatatact cagttacaac cttgtactta
    20581 ctttttcctg attgattaaa gttatcaaca actttttgcc aagcttttcc ttcatttgtt
    20641 tcgtcagaga attgtaccca gactttaata tcatttgaag aactcgcttg ttttgagtta
    20701 gttcctccac tacaacctgc aagtatagct aacgatagcc ccgcaacaac agataacatt
    20761 gtacctttac gcatcatttt cctccttttt gaaacgtttc attttttatt tattttttaa
    20821 acaagcttct agcctatttt tgaaacgttt catttgttga ttatattata acagcgcttt
    20881 cattaattgt caagcgcttt ttaaattttt tttgttgttt tatctcccca aaaatatgtg
    20941 ggaattacga ttcgtttttc tagaatctct tctcgcttaa tcattttcag tatcattgca
    21001 acagattctt ttgccatcat accaatatct tgaactattg tagacactag ataagattga
    21061 tcgacagaag tttttaaacc atcaaaccca attatctggt aatcatcagg tgctattttc
    21121 cccagttctt tcataacact aataactctc agagccatca tatcatttat tgtaaatata
    21181 ccatcaattt ctttatgaga ttgcaaaaaa attcttatct gatcttcagg atttattaaa
    21241 ggttctttca tttcaaaatt atagacatct actcctaatt ccttagcttt ttctctgaat
    21301 cctttacttc tgagtatagt ctcattctca tacatattaa ttgaaccaat aaaagcaagg
    21361 tgcttattat cccttctaac cagttcctct gctgcagttt gtcctccttt gtaatttgct
    21421 gaagtaacat agcatacatt ttccgaaaaa tgtctatcta tacttacaaa cggtaaatca
    21481 gataaaatat atttgtcaat atcagaatat gtaataccaa taattccatc cactttattt
    21541 tgtttcaaca tttcgatata ttcgatttca ttttgtgaat cgctatcagc gttacaaata
    21601 aataatttat aattatattt taataactct ttctcaacat gataggcaaa ctccgaaaaa
    21661 aatggatgcc atatgctcgg aataatcaaa gcgatagttt ctgttctatt ctttttcata
    21721 cctcgagcat aattatcagg gatatagtcc aatgttttta tagccctttg aactttcctt
    21781 aaagttactt ctttaatgcc tttttcttta ttaattacac gtgaaacagt tccaacacta
    21841 actcctgctt ctaaagcaac atctttcatg gtaattgatt ttctttgttc taccatatta
    21901 tcaactcctt tcaatatata gtatcatgca aatgcttttt aagcaactat ttctcaatca
    21961 tttttggcca gatcatttat cccatcatga ataaaatcac tccaattagc ttttgaaaat
    22021 acttcaattt tcatgtgtaa acatctacat aaaacaggaa aagccttggt ttcatggctt
    22081 ttttcgtatc ttctacaaaa aaagcaagag ttttagaggg ctataaatct agatgtacat
    22141 ttttcttaaa tgattgaagg tcttttctta acaaaaacac cctaaaaatt agactttttc
    22201 tgtctaactt ttgaggtaca gttcaaacgc gaaatagcgt ttttttgtta tttttggtta
    22261 ctcatctaat cgaataaaca tcatggcatt taacaagtat atgagtgaga ccgtgtttat
    22321 attatttgaa tagatgagtc tcttattttc aataggagga ataataaaat tggaaataat
    22381 gatatcataa ggtgaatctt ctaaagattc ctttgataat tctaattcgg tccaaacctc
    22441 cagttcaaaa ttattgctac agtaataaga aagtgtctct gcaacgaatt ttgcatgata
    22501 ctgatcaaaa ttactcataa ctaaaacctt tagtttaggc tgattttgta gcaaattaat
    22561 caccaaatgt ttggtatgag tgatgaaggt ataagataga tgatttacca tcattgaact
    22621 agaacaaacc tcaagagtct ctaaatagtg agaaagctct ttttttatat ctgaaacaaa
    22681 ttttggaaaa atattttgaa agttcctgat tgtattccct ttttgatcaa ataaaataaa
    22741 ctcagtaaac aactcttgac gatacagatg tgcggtatta tgcagatgcc aaatcagatt
    22801 atccttattc tccatttcaa tctgatactt gactgaaatc tgatcaataa aatcactcaa
    22861 tagatggtaa gatttttcaa cataactatc cttttttacg catttcataa agagactttc
    22921 atctatgaaa aacatttttt gaaagtaaga cacaaataat tggcaaacaa cttcttcatc
    22981 taaagagata ttgtattctg attcaaaact ctgagcaaca ccttctattc cttctgcctg
    23041 cattaaaaaa tccaaacttt ggtcgttaaa agaatcttta tctacttcca taaaatgacc
    23101 aaactttatt ctatataggt tcgtaactag gagcaacttt agcattctat gcgttgacaa
    23161 attcattgga aagcttgttt ccttataaac caattctaac aattgagata gtggctctga
    23221 tgaaaaattt tcaaatggcc attctaggaa ataatatttt tctgaaaaat attgtgcaaa
    23281 aaagtaacga atgtctctct catttccaat gatttgaaca ggggtcagac tgacttcaaa
    23341 ttgaaattgc cttttaatca ctttattgat ttggctaata atacgataga gcgaagatga
    23401 actgatataa aattctttac aaatactctc agcttgacaa ccttcattaa agaagatgaa
    23461 ttctaaaatc gaaaaatgag ttgaatgttt aaagaaatga tggtaaacca tttcaatatc
    23521 actatcatcg gtattaataa tgcgtatacc attagtagaa gaatgaaaaa tcaagtcagg
    23581 aaaagcagat ttaacatggg atagatcatc tttgactgca cgttctgtac aatttaataa
    23641 ctctgctagt tcagaacgat gaaaccaacg tttatgttca aataataatt ctaataattc
    23701 taattgccta tgactttttt tagataataa atctctcatg aatatctttc tctctttata
    23761 aattatcgga ttaaacctct tgcaattata ccacaaagaa taggtatagc atgatataac
    23821 gacttttcct aaaatctttt atttcgtata ataacactac ggagacaata tataaacaat
    23881 tttcttattt taccgtctat tgagggcgtg aatacagaat caaattcaag tctaaagatt
    23941 atatttttaa ttttaaaaat tatataatag caacaattaa agaatttgat tttttaaaat
    24001 tatataataa taacaatcga aa
//
LOCUS       DAVHSI010000032        22784 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.032, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000032 DAVHSI010000000
VERSION     DAVHSI010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22784
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.032"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(198..395)
                     /gene="blpI"
                     /locus_tag="VVR21_001472"
     CDS             complement(198..395)
                     /gene="blpI"
                     /locus_tag="VVR21_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU6055331.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            677..1264
                     /locus_tag="VVR21_001473"
     CDS             677..1264
                     /locus_tag="VVR21_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU6055332.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1191..2834
                     /locus_tag="VVR21_001474"
     CDS             1191..2834
                     /locus_tag="VVR21_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU6055333.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2845..4206
                     /locus_tag="VVR21_001475"
     CDS             2845..4206
                     /locus_tag="VVR21_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU6055334.1"
                     /translation="MNSNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVTNQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFSYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREILITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4263..4418
                     /gene="blpC"
                     /locus_tag="VVR21_001476"
     CDS             4263..4418
                     /gene="blpC"
                     /locus_tag="VVR21_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU6055335.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKA
                     LELPIQL"
     gene            complement(4460..5800)
                     /locus_tag="VVR21_001477"
     CDS             complement(4460..5800)
                     /locus_tag="VVR21_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6055336.1"
                     /translation="MNIAWILLYALVINGLEIVIFFKVDGIGLTFDRIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFIKAREKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTNLNTTCQNQVFRQVLTVIHAE"
     gene            complement(5814..6551)
                     /locus_tag="VVR21_001478"
     CDS             complement(5814..6551)
                     /locus_tag="VVR21_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055337.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSTEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6556..6894)
                     /locus_tag="VVR21_001479"
     CDS             complement(6556..6894)
                     /locus_tag="VVR21_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055338.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKQGE"
     gene            7170..7499
                     /locus_tag="VVR21_001480"
     CDS             7170..7499
                     /locus_tag="VVR21_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU6055339.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7667..8716)
                     /locus_tag="VVR21_001481"
     CDS             complement(7667..8716)
                     /locus_tag="VVR21_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055340.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8713..9444)
                     /locus_tag="VVR21_001482"
     CDS             complement(8713..9444)
                     /locus_tag="VVR21_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055341.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVESLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9512..9922
                     /locus_tag="VVR21_001483"
     CDS             9512..9922
                     /locus_tag="VVR21_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU6055342.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9932..10219
                     /locus_tag="VVR21_001484"
     CDS             9932..10219
                     /locus_tag="VVR21_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055343.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10381..10620
                     /locus_tag="VVR21_001485"
     CDS             10381..10620
                     /locus_tag="VVR21_001485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055344.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYYSPFHN"
     gene            complement(10954..12090)
                     /gene="dnaJ"
                     /locus_tag="VVR21_001486"
     CDS             complement(10954..12090)
                     /gene="dnaJ"
                     /locus_tag="VVR21_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU6055345.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12434..12838)
                     /locus_tag="VVR21_001487"
     CDS             complement(12434..12838)
                     /locus_tag="VVR21_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEU6055346.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGMIWTVV
                     VFLMINWNYIANTKKRQKYINISVLIGYLKSK"
     gene            complement(12849..14672)
                     /gene="dnaK"
                     /locus_tag="VVR21_001488"
     CDS             complement(12849..14672)
                     /gene="dnaK"
                     /locus_tag="VVR21_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU6055347.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15141..15665)
                     /gene="grpE"
                     /locus_tag="VVR21_001489"
     CDS             complement(15141..15665)
                     /gene="grpE"
                     /locus_tag="VVR21_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU6055348.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15692..16726)
                     /gene="hrcA"
                     /locus_tag="VVR21_001490"
     CDS             complement(15692..16726)
                     /gene="hrcA"
                     /locus_tag="VVR21_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU6055349.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQESANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16890..17399)
                     /locus_tag="VVR21_001491"
     CDS             complement(16890..17399)
                     /locus_tag="VVR21_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU6055350.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSCFGLFYFEQ
                     GQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIYGYFR
                     LKRKYRVDE"
     gene            18006..20339
                     /locus_tag="VVR21_001492"
     CDS             18006..20339
                     /locus_tag="VVR21_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6055351.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20352..21815
                     /locus_tag="VVR21_001493"
     CDS             20352..21815
                     /locus_tag="VVR21_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6055352.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTQ
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21815..>22784
                     /locus_tag="VVR21_001494"
     CDS             21815..>22784
                     /locus_tag="VVR21_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6055353.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYA
                     MQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT         7298 a         4589 c         4169 g         6728 t
ORIGIN      
        1 tatagttaag ttttttattc ctaccaatcc atcaactaag taaagcatca acgattacat
       61 aaacgattga taatataatt aaaattttgc taactatctt attctcatca ttcttagata
      121 actttgatat tttgtaagta agtaaataag acagtaaatt aatagcgata ataatactat
      181 atttaagaat cataatctta caaagaggac ataattcctg aacctacaca aataagtgtt
      241 gctgctcccc cagttatcgg accagtcgca gcagctaata gtactgctcc aatacaacca
      301 ccgattgcag atcctaaatt gcctcttcct ccactaacta tttcgagttc ttcattatcc
      361 ataacagaaa attgttccat catttttgta ttcatgacaa atactccttt tttctttttt
      421 tatttttgtc ttgttgtaac tttgataagt ttagtatatc atcgtttttt aaaatttttc
      481 atccagatct tgaattgtca tcgaaacgtc ttgaattagc ttttttattt caagccacct
      541 ctaaatgttt aaaaaaaata atttctaatc acttttttac cattcaggaa gttttaatga
      601 ctattcaaga tttcataaaa tatgaactta gttttatgac ataatagacc tatccactat
      661 atgaaaggaa ttgccaatga cttcttataa acgtacattt gttcctcaaa tagatgcgag
      721 agactgtggt gtcgctgcct tagcctcgat tgctaaattc tatggttcag atttttctct
      781 agctcacttg agagaacttg caaagaccaa taaagaaggg acgactgctc ttggcattgt
      841 aaaagccgct gatgaaatgg gctttgaaac aagacctgtt caagcagata aaacgctctt
      901 tgacatgagt gatgtcccct atccatttat cgttcacgtt aacaaagaag gaaaactcca
      961 acattactat gttgtctatc aaacaaagaa agactatctg attattggtg atcctgaccc
     1021 ttctgtaaaa atcactaaaa tgtcaaaaga acgctttttc tatgaatgga ctggagtagc
     1081 tatttttcta gctaccaaac ccagctatca accccataaa gataaaaaga atggtctact
     1141 aagcaagctt ccttcctctg attttcaaac aaaaatctct cattgcttac attgttctct
     1201 caagcttatt ggtcactatt atcaatatag gtggttctta ctatctccaa ggaatcttgg
     1261 atgaatacat tccaaatcag atgaaatcaa ctttaggaat catctcagtt ggtctggtta
     1321 tcacctatat cctccaacaa gtcatgagct tttccagaga ttatctccta accgttctga
     1381 gccagagatt aagcattgat gtgattttat cctatattcg ccatattttt gaacttccca
     1441 tgtctttctt tgcgacacgt cgtacaggag aaatcatttc acggttcaca gatgctaact
     1501 ctattataga tgccttggct tctaccattc tttctctttt tctggatgtt tctattctga
     1561 ttcttgtagg gggcgtctta ctggcacaaa accctaatct cttcctcctt tctcttcttt
     1621 ccattcctat atacatgttc atcatctttt cttttatgaa accttttgaa aaaatgaacc
     1681 atgatgtcat gcaaagtaat tctatggtta gctctgccat tatcgaagat atcaacggga
     1741 ttgaaactat aaagtcgctc acgagtgaag aaaatcgcta tcaaaatata gacagcgaat
     1801 ttgtagatta tttggaaaaa tcctttaagc tcagtaaata ttctatttta caaacgagtt
     1861 taaagcaggg aacaaaatta gttctgaata tccttatcct atggtttggc gctcaattag
     1921 tcatgtcgag taaaatttct atcggtcagc tgattacctt taacacactt ttttcttact
     1981 ttacaactcc tatggaaaat attatcaacc tccaaaccaa actccaatct gcgaaggtcg
     2041 ctaataaccg tttgaacgaa gtctatctag tcgaatctga atttcaagtt caagaaaacc
     2101 ctgtccattc acattttttg atgggcgata ttgaatttga tgacctttct tataagtatg
     2161 gttttggacg agatacctta acagatatta atctcacgat taaacaagga gataaggtta
     2221 gcctagttgg agttagtggt tctggtaaaa caactttagc caaaatgatt gtcaatttct
     2281 ttgaacccta caaagggcat atttccatca atcatcagga tattaaaaac attgataaaa
     2341 aagtcttgcg ccgtcatatt aattacctac cccaacaagc ctatatcttt aatggctcta
     2401 tcttggaaaa tttaaccttg ggcggtaatc atatgattag ccaagaagat attctaagag
     2461 cttgtgaatt agctgaaatc cgtcaagaca ttgaaagaat gcctatgggc tatcaaactc
     2521 agctctctga tggagctggt ctatcaggag gacagaagca acgaatagcc ctcgctcgtg
     2581 ctcttttaac taaatctcct gttttaatac tagatgaagc tactagcggt cttgatgtct
     2641 tgactgagaa aaaagttata gataatctta tgtccctaac tgataaaacc attctctttg
     2701 tagcccatcg tctcagtata gccgaacgaa ccaaccgtgt cattgttctt gaccagggga
     2761 aaatcattga agttggtagc caccaagagt taatgcaggc gcaaggcttc taccatcatc
     2821 tattcaataa ataaggagaa tgtcatgaat tctaatcttt ttagaagcgt cgagttttat
     2881 cagagacgtt accataacta tgcgacagtg ttaattatac ctctttcatt actgtttact
     2941 ttcatcttga ttttctccct tgttgccaca aaagaaatta ctgttacttc ccaaggagaa
     3001 atcgccccta caagtgtcat tgcatccatt cagtcaacca gtgataatcc tatcctagct
     3061 aatcatttag tgacaaatca agtagttgag aaaggtgact tactcatcaa atactctgaa
     3121 acaatggaag agagtcagaa aactgcctta gcaactcaat tacaaagact tgagaagcaa
     3181 aaagaaggac ttggaatttt gaaacaaagc ttagaaaaag cgactgatct tttttctggc
     3241 gaggatgagt ttagctacca taataccttt atgaatttta ctaaacaatc ccatgatatt
     3301 gaactcggta tctcaaagac taacactgaa gtttcaaatc aagccaatct tgccaatagc
     3361 agttcatcag ccatcgaaca agaaattaca aaagttcaac aacaaattgg agaatatcaa
     3421 gagctgagag atgctatcat aaataacaga gctcgcttac caactggcaa tccgcaccag
     3481 tcaattttaa atcgttatct tgtagcctca caaggacaaa cacaaggaac ggcagaggag
     3541 ccatttttat ctcaaattaa tcaaagtatt gcaggtcttg aatcatctat cgcaagcctc
     3601 aaaattcagc aagctggtat cggaagtgta gcaacttatg ataatagttt agcaaccaaa
     3661 attgaagtac tccgcactca atttttacaa acagcttctc agcaacaact aaccgtggag
     3721 aaccaattaa cagaattaaa agtacaacta gatcaagcga cacagcgctt agaaaacaat
     3781 accttaaccg ctccaagtaa aggtatcgtt catctgaaca gcgaatttga aggtaaaaat
     3841 agaattccaa ctggtacaga aattgctcaa atattcccta tcatcacaga tacaagagaa
     3901 atactaatca cttactacgt agcttctgac tatctacctc tactagataa aggacaaact
     3961 gtaagattaa aactggagaa gattggaaat cacggcatta ccatcatcgg ccaacttcag
     4021 acaattgatc aaactcctac cagaacagag caaggcaatc tctttaaatt aaccgctctt
     4081 gcaaaactat ctaatgagga tagtaaactc atccaatatg gcttacaagg tcgcgtcact
     4141 agtgtaactg caaagaaaac atattttgat tatttcaaag ataaaatttt aacccattct
     4201 gattaatttt cagataacac tctataacta tttattatct tatcaaaaag gagaatcata
     4261 acatggataa gaaacaaaac ctaacttcat ttcaagaact aacaactacc gaactcaacc
     4321 aaattacagg tggaggatgg tgggaagaac tcttacatga aacaatttta agtaaattta
     4381 aaatcacaaa agcacttgag ctacctattc agctataaaa acaagaccga gaaacaagaa
     4441 ctctcggtct tgttttttat cattctgcat gtatcacagt aagtacctga cgaaagactt
     4501 gattttggca ggtagtattt agattggtat tgggatgact ttccacaatt ttcataacgg
     4561 tatagagacc aactcctctc tcctcccctt tagaacttgc tccaaaggag aagatttcag
     4621 aaatatcgat gccctcttct ttgatggagt tttcaatgat aaaagtctcc tgtgctccat
     4681 tttttaaaaa ggcgattgaa acatgaggtt gactggcctc tgcactagct tcaatagcat
     4741 tgtcacaaag gatagacaca atggttagaa aatcaagtag gctcatcccc tcaacctgaa
     4801 tctcctcagg aacttcaaca ttaaagacaa tgttcttttc tctagctttt ataaattttc
     4861 cagctaggag actcttgagg gcacggtcac gaatattcac caatctgccc aggtcatatt
     4921 tattgtcctg caatttctga ctggaatccc ttaagaccga gtcgtagatc tcttttatct
     4981 gctccatatc ctcctcttca atgcccaaac gtaagctggt taagaggtta gtgtagtcat
     5041 ggcgaaaact ccgaatttcc ttgtaaagtt cctctatatg ccgactatag cgttccatat
     5101 ctctgtagcg caaggtctgc tcttggttca gttcctcctg aagtttttcc ttcaaatagg
     5161 tatccaattt cttgataccc cccataaaaa agagtaggta aaacactagg atgagatggc
     5221 gaacagtcgt tgattgaata ccttgttcat attcaaggta agatagactt tgcatcacta
     5281 gataataagc ccccattgcc cagttaatct tagtaagaga cttttgaaaa cctgtatcta
     5341 gaaactccct tctcaatcta gtgaaatcat agtctaacca tttcaaaaag actaaaacta
     5401 tgaagcaaac gaatatcata atcaataaaa agataggatt gccatcccca tctacaattc
     5461 cttgccccaa aaatggaagc acaaaatagg aaacacctct gtaaaagagc tctactaata
     5521 tcattgggaa gagaccataa aaaataagga tttttttagg aagccctctt aacaataaga
     5581 aagatagacc tataccgaac aaaggttcta taaaatagga caaatattta cttacagcca
     5641 aaaattgaaa agtcgtaaaa atgatcccta gaagaaattt cagaagaaag gccttaaaaa
     5701 ttctatcgaa agtgagacca attccatcta ctttaaagaa aatgacaatt tctagtccat
     5761 taataacaag tgcatacaac aatatccaag caatgttcat aaactctcct agctcagtgt
     5821 aagttattaa tagcctcaga cacttccctg accttataac gcgcgatcag acaacttcca
     5881 ccattgggaa agaaaaggag tttttctttc ttatccaaat gcaccacatt tgcaggattg
     5941 atgagaaaag agcgatggca ctgcaagaga cggggttcct gcttgaaaac ctcctctaaa
     6001 ctcgctgtaa attccagcct gtctgtcttg gtatagagaa taacacgatg gggtcttggg
     6061 gatgtttcga gatagtaaac ctctttaaaa ggatactgaa attgggcaaa ttttgattta
     6121 aagtaaaagc aatcttccgc cagactttta ctatcttgac tattggcata gaggagggct
     6181 gtctcgattc gagattcaaa ctcctctgtc gaaagggcct tatcaatata gtccagagca
     6241 gacacttggt agcgaaagga caggggcata aactccgagt gagtcgtcac aaagacaatc
     6301 agggcatagg ggtcttgttc ccgaatcttt ctagccactt ccagcccctt catctcctca
     6361 tttcgaatct caatatccaa aaagaatagc tgatgggccc ccttctcatg cacctctgcc
     6421 agcagttggt ctggcttgcc aaatacctca aaagagctgg gagtgatatg atgttccttc
     6481 aagagtttct caatcgtcgt ttcaatccta gtctgttggg aaaaatcatc ctctaaaaca
     6541 aatattctca tctttttact ctccttgttt taaccatttt tgacgaattt ctctatagcg
     6601 acgtctggca tacttgacag cgtattgacc ttcttctccg agaaaaagga ttctttcttg
     6661 aaaatcaatc gattttaatt tatcaagatt aaccaaacaa tttcgatgac atctcatcaa
     6721 ggtttcccca cattggttct caagattact taaattttga agcatattaa aactagcttc
     6781 ttctgtaaca atctgtacgg tatgggcttt agttggatgt gtttggatat agtaaatatc
     6841 gtcgatgttt actttataga ctgttttctg cgtctgaata atcatatatt tcattggatt
     6901 ctcctcctaa gaaaagaata acagaaaagg tctagcccaa gcacacccaa tcctaaacag
     6961 tctttgaaaa ctcctaaaag gattattttc tacaacatca tgatgagctt acaactattt
     7021 tatcataaaa ttcactcagc gcaattcaag acatttcaat gacaattaaa gatttgaata
     7081 aaaaaaaaga attaaaagtg ataaactaac agtatcaaaa cacagttgcc agaagtaaga
     7141 ctggcaccca gattaaagga ggcattccca tgacagatac agaccccatc aaaagagctc
     7201 atactttgat tactgactta aacaaagcct accaagcatg caaacaggca agcgctgacg
     7261 acgtccgctt tcaggagcaa ttaaactcta ttcttggttt tctagccaag gctgaaacag
     7321 tggataatcg attcttgatt gaactagaaa aattttacca gacttccagt cttctcatgg
     7381 gactcagcgc tcttgatcca gatgctccaa ctcgcgccgc ttggcgggcc tatgaccgct
     7441 tccactttga ccaagtcaag accaagttaa tactcaatga aaatcaaaga gcaaactagg
     7501 aagctagccg caagctgtac ttgagtacgg taagacgacg ctgacgtggt ttgaagatat
     7561 tttcgaagag tataagtctc tacggaccaa ccattatcct gtagtaacaa aaaagaagct
     7621 gagacaaact gaactcaact tcttttttag tgtcgtatca gcaatgttag tcctgcatct
     7681 gacgttttac ctgataaggc aaatacaaga ctagtaaaac caaaccagct cctagtaagg
     7741 ctagaagggc tagtttttct tggaaggtaa tcaacccaac aactaattcc acaagtaaaa
     7801 caaaactggt caatcctcga actacctcct gtaagccttt ttccttttgc cccttgtcca
     7861 gcggaaagag ttgggtcaaa tactggtagt caaaggcatg atagagggcc agcaactgga
     7921 agagcaagag gtagttaaag agaactacca ctgctgtcgc aatccaagct tgctcgataa
     7981 aaacctgcgc cagtacggaa agtaagagaa gacgaagact gagagcaaag aggtcgccat
     8041 ttcgcagata agaacgcaga tagagatttt gccaaatctt cccaggcacc ttctgaacag
     8101 cctttaagat aaagtccaga taggcacgac gcttgacact gtttgaaatt cccttgacct
     8161 gcgtaaagag ggcaaagaaa cgaagcaaga cttgcttacg cttgctttct tgagaaataa
     8221 gatagtccca gtccagtcca gtttcagtaa aaaatttgct ggccttttga cgaaagtgga
     8281 aatattttcc tacccccaat aaaagcacat atagcagaaa aactggcaag ccataaccca
     8341 ttgctaaaaa taaaggcgca aataacagca agaaaagggt ctgtacaaag agccaaaaga
     8401 ctagggaaat gccagtttga cgcttgagat ggagcttgat ttcctcttct ccaactaaga
     8461 gaaagagctt gtctggagcc tccatatagg tggcaattcc tccccaaagt aagagtaaaa
     8521 cagacgtaat tcctacaaac aaaaggatag gccaatgatt ttcaggaaaa tgttgtaaga
     8581 gttgactgta ctggtaggct agaaagccca acaggacaag caggaataag acaaagtggt
     8641 cattgagcac atagcgcaga taaccaagac actccttacg aaaggcctgc tttctcttta
     8701 aaaacaagtc tttcatagat cctcctcttt ggtcagagcc aagtaaatat cattcaaact
     8761 agcctcaggc atatcaaagg cttcacgtag ttgcaggaga ttgcctttgg cacgcacctc
     8821 tcccttgtga agaatgacaa aggcatcaca catcttctcc gccgaatcca gcacgtgggt
     8881 actcatgaga atagacttgc ccttttgctt ctccacttcc aaaagctgaa tcaaatcaga
     8941 aatagccagc ggatcaagac caaggaaagg ctcatccacg atgaaaagac ttggatccac
     9001 cacaaaagca cagataatca tgaccttctg cttcatccct tttgaaaaat gaacagggaa
     9061 ccagtctaat ttctggtcca gacggaacat ctttaacaag gactctactc gttcgaaagc
     9121 cactttttgc tcaataccgt aagccatagc aaccgtttcg atatgctctc tgagggtcaa
     9181 ttcctcatac agactaggcg tctcaggaat gtagccaatc tgcttgcggt agctagtcgc
     9241 atctccttgc agagtcaggc cattgatatt gatggagcca ctataaggtg ccaacagacc
     9301 gataatctca ttgatcgtcg ttgatttccc agcaccattg agaccaatca aaccgaccaa
     9361 ctgcccactt tcaacagtaa aggacacatc tttcaaaaca ggaacatgaa catagccacc
     9421 tgtcaggttt ttaatttcta acatattttc tccaaatctg gtataatgta gctatattat
     9481 atcaaaattc agtacagtag aggtagattt tatgtcagat tgcatttttt gtaaaatcat
     9541 cgcaggggaa attcctgctt caaaagtata tgaagatgag caggtccttg cctttcttga
     9601 tatctctcaa gtaacactag gacacacctt ggtcgtgcca aaagaacact atcgcaatct
     9661 tttggagatg gatgctacga gcgccagcca actctttgcc caagtaccaa aagtagctca
     9721 aaaagtcatg aaagtcacta aggctgctgg tatgaatatc atttccaact gtgaagaagt
     9781 cgctggtcaa acagtttttc atactcacgt tcaccttgtg cctcgctaca gtgctgacga
     9841 tgacctcaag attgatttta tcgcccacga accagacttt gacaaacttg ctcaagtcgc
     9901 tgaaaccatc aaaaacgctt aaggagttgc tatgaaatta tccaacctac tgctatttgc
     9961 aggagctgca gccggaagtt atctggttac aaaaaatcgc caaaccatca cagatgaagt
    10021 cttgaatacc actgaccgcg ttcaagctat caaggacgat gtggatatta tccaaaacag
    10081 cctgcaaatc attaaccagc aaaaagaact tatcaaggaa taccaagaag acttgactta
    10141 caagtttaag gtcttggaaa aggatatcca gactagacta gctgtgataa aagaaatgca
    10201 gggaactgaa gataagtaaa aagagccccc cggctctttt ttaaaacgta aacaagttat
    10261 agtgaattga atttagaata gcacaccata gtttctaaag cattgttaga gattacttta
    10321 aaatcctctt atcaatttgt tcatattcta tttcaatcta ttatatatat cccatcaact
    10381 atgcatcata atttaggtaa ctcatactca ataaaaatca aaaagcaaac tagaaagcta
    10441 ggcacagact gctcaaaaca ccgttttaag gttgtggata gaactgacga agtcagctca
    10501 aaacactgtt ttgaggttgt ggatagaact gacgaagtca gtaaccatac ccatggcaag
    10561 ccgacgctga cgtggtttga agagattttc gaagagtatt attcaccatt tcacaactaa
    10621 atcgaagact ttctgccgta atgaaaacac ctgaaacagc ttggtttcag ctgtccggaa
    10681 actttaaaac ttaggttcaa agtttaggta tggaacttcg aaggaggtca ctaccgtccg
    10741 tcattactta ggaaagtctt aaaaaatcta taaagtaaaa agagcccgac agctcttttt
    10801 gtttatactc aatgaaaatc aaaaagcaaa ctaggaaact agccacgggc tgctcaaaac
    10861 actgttttga ggttgtagat acgactgacg aagtcagtca catatatacg acaagccgac
    10921 gctgacgtgg tttgaagaga ttttcaaaga gtattattct ccatcaaagg catctttaat
    10981 atggtcaaag aagccttttt tctttggatt tactttcaag tcaccagcag ccgcgaattc
    11041 tttcaaggct actttttggc ggtcgttcaa gcctgtcggt gttacgacat taacagtaac
    11101 gtattggtca ccaactgcac cgccacgaag gctcggtgcc cccttactac gtaggcggaa
    11161 tttcttacca gtctgagttc cctctggaat aaccaattca acatcaccgt gaacagttgg
    11221 aatatctact gtatcaccaa gagccgcttg gacaaagttg aggttgagat tgtagaagat
    11281 agtcgttcct tcacgttcaa acttgtcgct agcttctaca gaaactacta catacaagtc
    11341 cccataaggt ccaccgttaa agcctgcttc gccttgacca gcgaggcgaa tttgttgacc
    11401 tgtttccaca ccagcaggga ttttcacatg tacgctatga gcttgtttct catgacctgt
    11461 tccatgacag gttgtacatg gatatttgat ttcttttcct cgaccgtgac agacatcaca
    11521 ggttacttgg cgacgcatca taccaagagg agtctgcgta tcgacgttaa tgacaccagc
    11581 gccatgacag cgtccacaag tgactggact tgtccctggc ttagcaccag agccattaca
    11641 tgtacgacag ccagcttcac gatgatactt aacttccttc tcagttccga agatagcttc
    11701 ttcaaaggtc aaattgacac gatactggag atcatctcct tggcgaggag cgtttggatt
    11761 gcgcgaagaa ccgcctccgc cgaagaaact tgagaaaata tcctcaaaac caccgaagcc
    11821 acctgcccca ttgaaaccac cgaaaccacc agctccacca aaaccaccat tggcgcctgc
    11881 agcaccatac tggtcatagg cagcacgttt ttggtcgtca ctcaaagtct cataggcttc
    11941 ttgaacttcc ttgtacttgt cctcagcacc aggctccttg ttgatatctg ggtgatattt
    12001 tttggaaagc ttacgataag cctttttgat ttcgtctgcc gaagcgtttt tggatacccc
    12061 cagacgatca taaaattcag tattgttcat aattcaagat acaaagggcg tcaaacggac
    12121 acagccatct aggagttttg acgacggacg cttacgtcct agaaaaaact atctttttgg
    12181 cacagtccgt agcccgtgtt cagttacgaa cacccttatt cctttctatt gatgttctga
    12241 atcgaaccac catttaggtc ggattcaatt cctttctttt atatttagta agaaattctg
    12301 aaacccgtgt tcagttacga acactctttg ttcctttcta ttgatgagac aaaacccaaa
    12361 caaataagat tccgtccctt tttatcgaaa aacagaggct gggttgcaac ctctgcaaat
    12421 aagtaaatta actttatttt gattttaaat atcctataag tacagaaata tttatatatt
    12481 tttgtctctt cttagtattt gctatataat tccaattgat cataagaaat acaactactg
    12541 tccaaatcat accaattatg aacggtatta caaatttata tgtttgtatt tctaatgata
    12601 tcatagctga taccagcgcc gatacaaatg cagacaacaa tactgaggta acaaaattcc
    12661 ttaccgcttc atcatttttg atacaactat catgttcagc taatataatt tctctatatc
    12721 tagctaaata ttctattgga atattatcaa taaaatcttt tgatgttcta tagttatcag
    12781 cttgattaca aaaatcatta taaacttttc gtgtattttt tagatactct tcatccaata
    12841 cactcgtctt acttttccgt aaactctccg tctacgacgt catcgcctgc gtttcctgtt
    12901 gcttgtgcgc cttctgctcc ttcttgagct tgttgcgctg ctgcggcttg ttcgtagagt
    12961 ttaacagcaa gtccttgagc tttttcgttc aatgcttcaa gtttcgcttt catgtcgtcc
    13021 aagttgttgt cttcttgagc tttcttaagg tcatcaaggg cagcttgggc agcgtcacgt
    13081 tctgcgtcga agcctttacc ttcagtttcc ttgattgtct tttcagtcgc aaagattgct
    13141 tggtctactt cattacgaag gtctacttct tctttacgtt tcttatcggc ttcagcgttt
    13201 gcttctgcat ctttcatcat gcggtcgatt tcttcgtcag tcaaacctga gttcgattgg
    13261 atgacaatag tttgttcttt ttgagttcca aggtctttgg ccttaacaga cacgataccg
    13321 ttcttgtcga tgtcaaatgt tacttcgatt tgaggaattc cacgaggtgc agctgggata
    13381 tcagtcaatt ggaagcgtcc aagagtcttg ttatctgctg ccattgggcg ttcaccttga
    13441 agaacgtgga tatcaacggc tggttggttg tctgctgctg ttgagaagac ttgtgattta
    13501 gatgttggga ttgtagtgtt gcgatcgata agttttgtaa atactccacc cattgtttcg
    13561 ataccaagtg acaatggcgt tacatccaga aggacaacgt ccttgacatc accagtaatc
    13621 acaccacctt ggatagccgc acccatagca actacttcat cagggtttac tgatttgttt
    13681 ggttctttac cagtttcagc tttaacagct tcaacaacgg cagggatacg agttgaacca
    13741 ccaacaagga taacttcgtc gatttctgac aagctcaaac ctgcatctga aagggcttga
    13801 cgaactggaa cttttgtacg ttcaacaagg tcacgagtca aatcgtcaaa tttcgcacga
    13861 gtcaaagtca tttccaagtg aagaggtcca gcctcacctg cagtgataaa tggcaagctg
    13921 atttgtgttg aagttacacc agaaaggtct ttcttcgctt tttcagccgc atctttcaaa
    13981 cgttgcattg ccatcttgtc agtagacaag tcgataccgt tttctttctt gaattctgct
    14041 accaagtggt caatgatttt ttggtcaaag tcgtcaccac caagtttgtt gtcccctgca
    14101 gttgacaata cgtcgaagac accgtcaccc aattcaagga tagagacgtc gaatgtacca
    14161 ccaccaaggt caaataccaa gattttttct tctttgtcag tcttgtccaa accataagca
    14221 agagctgctg cagttggttc gttaacaata cgttctactt caagaccagc aattttacca
    14281 gcgtcttttg ttgcttgacg ttgagcgtcg ttgaagtaag ccggaactgt gataacagct
    14341 ttggttactt tctcaccaag gtagtcttca gcgtagcctt tcaagtattg aaggatcata
    14401 gctgagattt cttgtggagt gtattctttt ccatttgcag aaactttttc agaagttccc
    14461 atcttagatt tgatagagat aactgtatct gggtttgtga ctgcttgacg ttttgcagca
    14521 tcaccaacga tgatttctcc gtttttgaat gagactacag atggagttgt gcggtttcct
    14581 tctgggtttg cgatgatttt gctttcagtt ccttcaagaa ctgcaactgc tgagtttgtt
    14641 gtacctaagt caataccgat aattttagac atgtgttttt ctccttgtta gttaattttc
    14701 tatttttctt tttgatactc ttcttaagtg gcgacgccgt cagagcttga cttcgtcaat
    14761 ctctttgact aaactttgag cctaaggtct caaaatttgc gcaaatagcg ccacggcgaa
    14821 gagtatcgtc tttggttcgc ttcgctcact attacaaagc caaacatatt ttatctttct
    14881 tcatagttta ttgtcgtttc ggacaagttt tctattatgt aaattgcgac acgaggagtc
    14941 gaaatcgatt ttatttcgac gacgagttag taaggaagct agacaaacgc catagcgatt
    15001 gccgttttct gacgagttgc tttagctacc gtcagaattg ccgaatcgaa cacgccctaa
    15061 gctctgagta aaaaagatag attttcttgt gttcatcgaa cacttcgtca atctcctatt
    15121 tttactgcgg gctttgtatc ttagttatac accactacca ttgctgggcg taggatgcgg
    15181 tcatggagtt tgtagccttt ttgaaagact tgggcgatgg tatctactgg gtgttcatcg
    15241 tctgctggga gagtttggat ggccatatgg tagttatggt caaattcgcc atctgctgcg
    15301 atttcttcaa ttccttcttc tttcaaagcg tgaatcaagc tttcttgcac catccccaag
    15361 cccttcttca catcatctgt caaaccttca actgcaagtg cacgctcaag gttgtcaaga
    15421 gatggtaaga ttgcttttgc caagtcctgg ctacgataac gttgcaagtt ttgacgttct
    15481 tcattggcac ggcgttggat attttgcatt tctgcatgag cgcgaagata tttgttttcg
    15541 aactcatctg cacgttcatt tgccaagtcc aactcagact tttcaggagt tgtttcttca
    15601 gctgtttcca caacttcctc ttcttgaact tcttctactt cttcattttt tatatcttgg
    15661 gccatgttcg cctcctttaa tgatttcaat cttaatgtac ttcgtaatga ttactgctga
    15721 ggtagcggta aaaatctgtc aacttcatgg tcaaaacacg gttgaccaca ttgacttgat
    15781 tgattagctg ttggtaatcc agattaactg gaccgataat ggctagaatt ccaactcccc
    15841 gataaggaat gaggaactta ctactaatca ccgctaggtc agctaaacag gactcttgac
    15901 cgtctgcaac acgaacattt tgcatctgat cctcacgcaa cccctcacga atctccaagg
    15961 ccaccttttg cggttggtca aagaactgat aggctgctag attggcaaaa ttcaagagat
    16021 tgaccttgcc cgccatcaca atgttttcgt tgaacatttc cttaaagatg tgttcaaaga
    16081 gatcgatgac attatccgtt gttgtaaagt aacgctggat aatctgcgga atctccgtcc
    16141 gaatcttgta gtgaatatct aaaacggtgt gaccgaggaa acgttcctga atgatgctct
    16201 tcagtttcag caaatcctcc tgcaagaagt tccttggaat cagaaactga ctagtaaccg
    16261 ttcgcgactc gtctagggta aataccgcca aggctgtatg ttgccccaaa acaacgatat
    16321 caaaggctgt caaacgttgc ctgctcggct caacatccag tgccactacc gtacagccac
    16381 tcaggtctgt tagcaagtta gcagactctt gcagaatatc ctccaatttg aagaattcct
    16441 gatcaaaggc tttgacaatc tcatatacct cattttcagc cagtcggtca aaatccagtg
    16501 agtgtttcac atagtactga aaaccagcaa cacttggcat ccgaccgctt gaagtatgag
    16561 ccttctcaag caacccttgt ttttctagtt ccgccatgtc attacgaatg gttgcactgc
    16621 tagagttaat agactcttgc aaggcttttg atccgacagg ttcgtgcgtt ttggtaaaga
    16681 tgtcaataat cagatttaaa atatcctgct gacgctctgt aaccatctca tcactcctct
    16741 ctgtctgatc aattagcact caatgcatcc aagtgctaac tcatgattct attatacacc
    16801 cttagaagag aatgtcaaga caaaaactca aaaaattagc actcttttat caagagtgct
    16861 aaaaatcaat ctgaagacct agaaccttgc tattcatcta ctcggtattt cctttttagt
    16921 ctgaaataac cataaattag ataagaaatc agaaaagcat ataaaacaaa aataagaaag
    16981 aaagacatag aaagatcctc tctaaacaaa ctcatacaaa caacaagacc acctaagaaa
    17041 gtagctgtac aggaacgaag tctagatcgc ataacttccc atttgagccc cttactcata
    17101 tagacttgat cctctggaag taaatcagaa gacgatttac gaagaatcga acaagaacct
    17161 gctcctatca attcccaacc tctatctcta aaatcttgca gttcatgctt atatttttta
    17221 agaaatctag aatcatagat acggtagatg acatcgtctg gttgaccttg ctcaaaatag
    17281 aacaaaccaa aacaactcgt tctatacctc caacctttca aatgcatctc atgtaaatat
    17341 tcttcttcct tgtccaaatc aacaatggtg aaaatccgaa attctactct gctattcatt
    17401 gtcttacccc aaaattagaa aacatgcctg gcgttattta ttagataatt ctttccactt
    17461 ttgactcaat ctccaaaaaa tataagaaat ctgaatcgca aaaactatca ataaaaccca
    17521 atctattatg aaaatcaaaa atactcccca actgaaagaa ctacctccag tgacaaactt
    17581 tgagaaaacc ggtagtagag ctaaaaagag aagcaaaata ggaagcatcc gcattgttaa
    17641 aatccgtttg gcataaaaaa tctttattta aacgaaaata ttatggcaaa atttacgcca
    17701 gtttttgaac ggctgatgta gatattttat actttcaaaa tgtttaaatg tgattattta
    17761 tttttgaaaa atagctcacc agcccgactg aaagtgctta tagaatgata ataagtcgcc
    17821 tgccgaaaac agcgaaaaat agcggtgtta tgcggagata atctgacgcg atgcgaaagt
    17881 atattgcata cttattttca acaatttagc agagtatttt tataagtgtg atataataga
    17941 agtataattt gttctgatag tttattttat ggagaagtag atttttagaa tgcggagggt
    18001 tcaatatggt tgagtttata aagtctaaga aagaaatgag tgaggaggat attaaagcaa
    18061 atttcatcac tcctgctatt gtatccaaag gatggaaaaa tggtgagcat atcgcttacg
    18121 aagaatactt cactgatggt cgaattgaag ttagaggaga taaggctcgt cgtaaagaag
    18181 gaaaaaaatc agactattca ctgtattacc aatttggaac tcgaattgca attgttgagg
    18241 caaaggataa taaacacagc gttcgagcag gattacaaca agctattgaa tatggagaga
    18301 ttttagatgt tccatttgtt tattcttcga atggtgatgg ctttattgaa cacgaccgta
    18361 tcacgagaga agaacgtgag ctggagttag acgaattccc tactcgtgaa gaattatttt
    18421 ctcgtatgac gaaggaaaaa ggattgacgt acgaaattac agaagctatc tcaactccat
    18481 actatacaga cgccttctca atgaaaacgc cacgctatta tcagcaaata gctatcaacc
    18541 gtactattga aacagttgcc agaggacaaa aacgagtaat gtttgtgatg gcaacaggaa
    18601 cggggaaaac gttcatggct tttcaaatta ttcatcgcct tcgaaaagct ggtttggcta
    18661 aacgagtttt attcttagca gatagaaaca tcttagtaga ccaaacgatg gctgaagact
    18721 ttaggccatt cgaaaaggta atgacgaaaa ttacaccaaa acttttgact gctcctgaaa
    18781 aattaaattc ttttgaaatt tatctagggc tttatcagca actaactggt gaagatggaa
    18841 ctgaaacaca ttatcaaaaa tttgacaaag acttctttga tttaatcgta attgatgaag
    18901 cacaccgtgg ttcagctaag gaaaacagta actggcgtaa ggtaattgat tatttcagtt
    18961 ctgcgacaca gattgggatg accgctactc ctaaagaaac caagaatgct tccaatacgg
    19021 aatactttgg tgagccaatc tatacttata gtttaaaaca gggaatcgag gatggttttt
    19081 tggctccata tcgtgttatg agggttaatt tagatgtgga tgtggatggt tatcgtccag
    19141 aaactggaaa agttgatgct aacggacaat taatagaaga taggtactac ggcaggaaag
    19201 attttgataa aaccattgtc attgatgata gaacgcaaag agttgccaag tttgtttctg
    19261 attatatgaa gcaaaacaat gcacgatttg ataaaacaat tgttttttgt gttgatattg
    19321 accatgccga gcgaatgcgt gctgcacttg taaaagagaa tctagactta gtccaagaag
    19381 actatcgtta tgtcatgcaa gtaactggtg acaacgctga aggaaaagct caactggata
    19441 actttatgga tgtcaattct aattttcccg ctattgtaac aacgtctaaa ttattaacga
    19501 caggagttaa tgctaaaaca tgtcgtttga ttgttttaga ctctaatatc caatccatga
    19561 ctgaatttaa acaaattatt ggtcgtggca cacgtcttta tcctcaaaag gggaaagaat
    19621 tttttacgat tattgatttt cgaaatgtta ccaatttgtt tgctgaccct gattttgatg
    19681 gtgagccagt gaaggtgctg gaaacaggtg cgaaaacagt cagtggttct acgcccggtt
    19741 tcgtagatga ggaaggtgac ccagtagaaa aatatatcgt tacagacaag caggttacca
    19801 ttcttaattc tactgttcaa gtattggatg aaaacgggaa actgattacc gaaagcctga
    19861 ccgactacac tcggaagaat atcttaggta gctacgccac tttgaacgat tttatcacag
    19921 tttggcatac ggcggataaa aagaagctta tcttagacga actttataaa aaaggagttt
    19981 atctagatgc tattcgagag tcggagggaa tatcagaaca agaaatcgat gattttgatt
    20041 tactcctaaa acttgcctat ggtcaaaaag aattaaccaa aacggaacgt atcaataaac
    20101 tcaaacaaag cggatattta tataaatata gtgaggaagc gcgtgctgtt ttggaaattt
    20161 tactgaacaa atacatggat aaaggtattg gagaactcga aagcattgaa acattaaaac
    20221 ttccagaatt tcagatatat ggtggaacct tcaaaatcat caatacttat tttggagata
    20281 aaaaacgata tttacaagca attaaagaat tggagcaaga gctatttaca gtagcttaat
    20341 gaaaggaaag tatgtcaatt acatcatttg taaaaagaat tcaagatatc actcgaaacg
    20401 atgctggtgt taatggtgat gctcaacgta ttgagcaaat gtcttggtta ttattcttaa
    20461 aaatttatga tagccgtgaa atggtttggg aattagaaga agacgagtat gagtcaatta
    20521 tcccagagga attaaaatgg cgaaattggg ctcatgctca aaatggggaa cgggtattga
    20581 caggcgatga attacttgat tttgtcaata acaagttatt caaagagttg aaagagcttg
    20641 aaataacttc aattatgcct attcgaaaaa cgattgttaa atcagctttt gaagatgcga
    20701 acaactatat gaaaaatggc gtcttgttac gccaagtcat caatgttatt gatgaagttg
    20761 atttcaatag ccctgaagat cgtcattcgt ttaatgatat ttacgaaaaa attcttaaag
    20821 atattcaaaa tgctgggaac tcaggagaat tttatacgcc acgtgcagcg actgatttta
    20881 ttgccgaagt tcttaaccca aaacttggag aatcaatggc agaccttgct tgcggaacag
    20941 gaggcttctt gacttcgact ctgaaccgtt taagtagtca acgtaaaact agtgaagata
    21001 cccaaaaata taatacagct gtttttggta ttgaaaagaa agcatttcct catcttttag
    21061 cagttacaaa tctgtttctt cacgaaattg atgaccctaa aattgttcat ggaaatactt
    21121 tagagaaaaa tgttcgtgaa tatacggatg atgaaaaatt tgacattatt atgatgaatc
    21181 caccttttgg agggtcagaa ttagaaacaa taaaaaataa ctttccagca gaattacgga
    21241 gttctgaaac agctgattta tttatggctg tcattatgta tcgtttgaaa gaaaatggtc
    21301 gtgttggagt tattttacct gatggttttc tatttggtga aggtgtaaaa actcgcttga
    21361 aacaaaaact ggtagatgag ttcaacttgc atacgattat taggttgcct catagtgtct
    21421 ttgcaccgta tacaggaatc catacgaaca ttcttttctt tgataaaaca aagaaaacag
    21481 aagaaacttg gttttatcgt ttagatatgc cagatggtta taaaaatttc tcgaaaacta
    21541 agccgatgaa gtcagaacac ttcaatcctg ttcgtgactg gtgggaaaat cgtgaagaga
    21601 ttctggaagg taagttctac aaatctaaat catttacacc tagtgaattg gctgagttga
    21661 attataattt agaccagtgt ggttttccaa aagaggaaga ggaaatctta aatccctttg
    21721 agttgattca gaattatcaa gcggaaagag caactttaaa tcataagatt gataatgtat
    21781 tagctgatat tttgcagttg ttggaggaca aataatgaca ccagaacaac ttaaggcaag
    21841 tattctccaa agagcgatgg aagggaaatt agtgccgcaa aatcccaatg acgaacctgc
    21901 aagtgaatta ttaaagagaa ttaaagctga aaaagaaaaa cttatcagtg aaggaaaaat
    21961 caaacgagat aaaaaggaaa ctgagatatt tcgtggtgat gatgggaaac attatgggaa
    22021 gtttgctgat ggaagcactc aagaaattga tgttccttat gatattcctg atacttggga
    22081 gtgggtgagg ataaaatcaa tttattggaa ttttgggcaa aataagccag agaaatcctt
    22141 taggtatata gatacgtcta gtattgatag aaaaaagaac ataatcaact acaaaaatct
    22201 acaatatctt tcacctgaac aagcgccttc ccgtgctaga aaattagttt cgcagaatag
    22261 tgtcttattt tcaacagtta gaccatatct aaaaaatatt gctgtagtta gagaacttaa
    22321 agagtatttg atagctagta cagcatttat tgttttggat actttactta acgaaacata
    22381 tttgaaatat tatttattat cagataattt tatcaatcgt gttaataata aatctactgg
    22441 aacaagttat cctgcaatca atgattataa ttttaatcta ttattaattg ctctcccccc
    22501 actatccgaa caacaacgaa tagtagaagc aatcgaatca gctttagaaa aagtagatga
    22561 atatgctgaa agttataata gactagaaca gctagataaa gaatttccag ataaactaaa
    22621 aaaatctatt cttcaatatg ctatgcaagg aaaattagtt gaacaagacc caaatgatga
    22681 atcagtcgaa gttttacttg aaaaaatacg agcagaaaaa caaaaactct ttgaagaagg
    22741 caagattaaa aagaaagatt tggacatttc tattgtttcc caag
//
LOCUS       DAVHSI010000033        21031 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.033, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000033 DAVHSI010000000
VERSION     DAVHSI010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.033"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            5..75
                     /locus_tag="VVR21_001495"
     tRNA            5..75
                     /locus_tag="VVR21_001495"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VVR21_001496"
     tRNA            110..183
                     /locus_tag="VVR21_001496"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VVR21_001497"
     tRNA            266..355
                     /locus_tag="VVR21_001497"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VVR21_001498"
     tRNA            366..439
                     /locus_tag="VVR21_001498"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VVR21_001499"
     tRNA            443..515
                     /locus_tag="VVR21_001499"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VVR21_001500"
     tRNA            528..608
                     /locus_tag="VVR21_001500"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VVR21_001501"
     tRNA            613..683
                     /locus_tag="VVR21_001501"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VVR21_001502"
     tRNA            698..770
                     /locus_tag="VVR21_001502"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="VVR21_001503"
     tRNA            781..852
                     /locus_tag="VVR21_001503"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="VVR21_001504"
     tRNA            862..945
                     /locus_tag="VVR21_001504"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            1052..2329
                     /locus_tag="VVR21_001505"
     CDS             1052..2329
                     /locus_tag="VVR21_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU6055354.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2405..3889
                     /locus_tag="VVR21_001506"
     CDS             2405..3889
                     /locus_tag="VVR21_001506"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU6055355.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3950..5230
                     /locus_tag="VVR21_001507"
     CDS             3950..5230
                     /locus_tag="VVR21_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU6055356.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5234..5867
                     /locus_tag="VVR21_001508"
                     /pseudo
     CDS             5234..5867
                     /locus_tag="VVR21_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            6033..7145
                     /locus_tag="VVR21_001509"
     CDS             6033..7145
                     /locus_tag="VVR21_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6055357.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7468..7893
                     /locus_tag="VVR21_001510"
     CDS             7468..7893
                     /locus_tag="VVR21_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU6055358.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7904..8263
                     /locus_tag="VVR21_001511"
     CDS             7904..8263
                     /locus_tag="VVR21_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU6055359.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSLLLKNQGIYKALLGVFLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8370..9013
                     /gene="pcp"
                     /locus_tag="VVR21_001512"
                     /pseudo
     CDS             8370..9013
                     /gene="pcp"
                     /locus_tag="VVR21_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9041..9898)
                     /locus_tag="VVR21_001513"
     CDS             complement(9041..9898)
                     /locus_tag="VVR21_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU6055360.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10028..11170
                     /gene="tgt"
                     /locus_tag="VVR21_001514"
     CDS             10028..11170
                     /gene="tgt"
                     /locus_tag="VVR21_001514"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU6055361.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11271..13088
                     /locus_tag="VVR21_001515"
     CDS             11271..13088
                     /locus_tag="VVR21_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU6055362.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHRMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13241..14392
                     /gene="nagA"
                     /locus_tag="VVR21_001516"
     CDS             13241..14392
                     /gene="nagA"
                     /locus_tag="VVR21_001516"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU6055363.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFRGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14555..15613
                     /locus_tag="VVR21_001517"
     CDS             14555..15613
                     /locus_tag="VVR21_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU6055364.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLDTALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15764..16129
                     /locus_tag="VVR21_001518"
     CDS             15764..16129
                     /locus_tag="VVR21_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU6055365.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16205..17146
                     /locus_tag="VVR21_001519"
     CDS             16205..17146
                     /locus_tag="VVR21_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU6055366.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIYAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAVKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17094..18110
                     /locus_tag="VVR21_001520"
     CDS             17094..18110
                     /locus_tag="VVR21_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU6055367.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNFFSSGFHLVETISFLD
                     RSALLDKQCVTRMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18112..18435
                     /gene="comGC"
                     /locus_tag="VVR21_001521"
     CDS             18112..18435
                     /gene="comGC"
                     /locus_tag="VVR21_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU6055368.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQDDGRITEEQAKAYKEYHDKQNTS
                     QIVKD"
     gene            18353..18832
                     /locus_tag="VVR21_001522"
     CDS             18353..18832
                     /locus_tag="VVR21_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU6055369.1"
                     /translation="MDASRKNRLKPIKNTMINKILVKSLKIKAFTMLESLLVLGLVSI
                     LALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQK
                     LPVPKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18837..19097
                     /locus_tag="VVR21_001523"
     CDS             18837..19097
                     /locus_tag="VVR21_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055370.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19060..19521
                     /locus_tag="VVR21_001524"
     CDS             19060..19521
                     /locus_tag="VVR21_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6055371.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLIALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKEIAMGKSKADDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19499..19912
                     /locus_tag="VVR21_001525"
     CDS             19499..19912
                     /locus_tag="VVR21_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU6055372.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKKSEEKPEKKENS"
     gene            complement(20567..21031)
                     /locus_tag="VVR21_001526"
     CDS             complement(20567..21031)
                     /locus_tag="VVR21_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055373.1"
                     /translation="MYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYPIVIL
                     NKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIFEFID
                     STLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
BASE COUNT         6212 a         3728 c         4827 g         6264 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagta tagtgttagg
      961 aacgttgtta ttcttcgttc cttttttata ttatttttgg tataattata gttattcaaa
     1021 ttttatttag attaagaaag tgtaggggag tatgtcttgt tctatcgatt tattaaaaca
     1081 tcggtatttg aaaaatatta aagaaaatcc tgaattgttt gtcggaattg agttggagta
     1141 tcctgttgca agtttagaag gggatgctac agatgttgaa gttatgaagg atctatttca
     1201 ttatttagtt tctactttgg atctcaccgt agcaaaggta gatgattttg gcaatctgat
     1261 ccagttagta gatccgataa gtcaggatgc tattttattt gaagtttcct atacaacgat
     1321 tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc gaaaatcgtt tcaataatta
     1381 tatgaatgta attcagagaa agttagctga atcaaatcat gctattgttg gctgtggtat
     1441 ccatcccaac tgggataaaa atgagaattg tccagtggct tatccacgct atcagatgtt
     1501 gatggattat ttgaatttga gtagaaatat tattaaatca gatttacatc atttccctga
     1561 atatggtact tttatctgtg ggagccaggt tcagctggat atttcaaaaa ccaactactt
     1621 acgggtgatt aatgctttta ctcaaattga agcggctaag gcttatttat ttgcaaactc
     1681 tgaattttcg ggtgcggatt gggatacgaa aatttcaagg gatattttct gggaagaatc
     1741 tatgcatggt atctatccag agaatgttgg ggtcaatgct agactcctta atgatgaagc
     1801 tgattttttt gactatctaa atcattctgc gatttttact gcggaacgtg atgggcagac
     1861 ctattatttt tatcctattc aggctgggga ctatttggct acgtccgaaa tccaagcatt
     1921 tgctctgaat ggggatgagg ttattattta cccccaagag aaggattttg aaactcatcg
     1981 tagttaccag taccaagatt taacgactcg aggaacagtt gagtttcgta gtgtgtgtac
     2041 acagccactt gataggactt ttgcttctgc agcttttcac ttgggattat tggttaattt
     2101 agacaagtta gaagcttact tagaaacagc acctttcttt aaagtatttg gttatgatta
     2161 caagtcttta aggagacaat tttctaagaa aaatcttaca gatgaggaag aaactacgat
     2221 tattgaattt tccaaagact tactcctact agctgaggag ggactagtgg tgagaaataa
     2281 ggaagaaatg acctatttac agcctttgag agaagaattg agcctataat ttctcttata
     2341 aagggagaat tttctgaaaa atcatgatat aatggacgag actatagata aaggatagag
     2401 agtaatgaca ttagtttatc aatcaacgcg tgatgccaac aatacagtaa ctgccagcca
     2461 agcaattttg caaggtttgg cgacggacgg cggtttgttt acaccggtta cttatccaaa
     2521 ggtagatttg aactttgaca aattgaaaga tgcttcttac caggaagttg ctaagctagt
     2581 tttgtcagca tttttagatg actttacagt tgaggagttg gactactgta tcaacaatgc
     2641 ctacgatagc aaatttgata ctccagctat tgcaccatta gtgaaattag atgggcaata
     2701 caatttggaa cttttccatg gttcaacgat tgcctttaag gatatggcct tgtctatttt
     2761 gccatacttt atgacgactg ctgctaagaa acatggtttg gagaacaaga ttgttatctt
     2821 gacagcgaca tctggtgaca cggggaaagc tgctatggcg gggtttgcga atgtgcctgg
     2881 tactgagatt atcgtctttt atccaaagga tggtgtcagc aagattcaag agttacaaat
     2941 gaccactcag actggcgaca atactcatgt tattgctatt gatggtaact ttgacgatgc
     3001 gcaaacaaat gtgaagcaca tgtttaacga cgtggctctt cgtgaaaaat tgactaccaa
     3061 caagttgcaa ttttcatcag ctaactctat gaacattggt cgtctggtgc cacaaattgt
     3121 ttattatgtt tatgcttacg ctcaattggt taagactggt gaaattgtag ctggtgaaaa
     3181 ggttaacttc acagtaccaa caggaaactt tggaaatatc ttggctgcct tttatgccaa
     3241 acaaattggt ttgccagttg gtaaattaat ctgtgcttca aatgacaaca atgttttgac
     3301 agacttcttt aaaacacgtg tctatgacaa aaaacgtgag tttaaggtaa caaccagccc
     3361 atctatggat atcttggtat cttcaaactt ggagcgcttg attttccatc ttttgggaaa
     3421 taatgctgaa aagacaactg aacttatgaa tgccttgaac acgcaaggac aatataagtt
     3481 gacagacttt gatgcagaga ttttggacct ctttgcagct gaatatgcga ctgaggaaga
     3541 aacggcagca gagatcaagc gtgtttgtga gttagattct tatatcgagg accctcatac
     3601 agctgttgct tcagcagttt ataaaaaata ccaatcggcc actggagatg taactaagac
     3661 agtgattgct tcaacagcta gtccatacaa gttcccagta gttgcagtag aagctgtaac
     3721 tggaaaagca ggtttaacag actttgaagc cttggctcaa ttacatgaaa tctcaggcgt
     3781 tgcagtgcca ccagcagttg atgggcttga aatagctcca attcgtcaca agacaacagt
     3841 ggcagctgct gacatgcaag cagcggttga ggcttattta ggactttaag acagagggag
     3901 caaactcggt tgggaaacca actgagtttc ttttcatcag gaggagagat tgtttaagaa
     3961 aaataaagac attcttaata ttgcattgcc agctatgggt gaaaactttt tgcagatgct
     4021 aatgggaatg gtggacagtt atttggttgc tcatttagga ttgatagcta tttcaggggt
     4081 ttcagtagct ggtaatatta tcaccattta tcaggcgatt ttcatcgctc tgggagctgc
     4141 tatttccagt gttatttcaa aaagcatagg gcagaaagac cagtcgaagt tggcctatca
     4201 tgtgactgag gcgttgaaga ttaccttact attaagtttc cttttaggat ttttgtccat
     4261 cttcgctggg aaagagatga taggactttt ggggacggag agggatgtag ctgagagtgg
     4321 tggactgtat ctatctttgg taggcggatc gattgttctc ttaggtttaa tgactagtct
     4381 aggagccttg attcgtgcaa cgcataatcc acgtctgcct ctctatgtta gttttttatc
     4441 caatgccttg aatattcttt tttcaagtct agctattttt gttctggata tggggatagc
     4501 tggtgttgct tgggggacaa ttgtgtctcg tttggttggt cttgtgattt tgtggtcaca
     4561 attaaaactg ccttatggga agccaacttt tggtttagat aaggaactgt tgaccttggc
     4621 tttaccagca gctggagagc gacttatgat gagggctgga gatgtagtga tcattgcctt
     4681 ggtcgtttct tttgggacgg aggcagttgc tgggaatgca atcggagaag tcttgaccca
     4741 gtttaactat atgcctgcct ttggcgtcgc tacggcaacg gtcatgctgt tggcccgagc
     4801 agttggagag gatgattgga aaagagttgc tagtttgagt aaacaaacct tttggctttc
     4861 tctgttcctc atgttgcccc tgtcctttag tatatatgtc ttgggtgtac cattaactca
     4921 tctctatacg actgattctc tagcggtgga ggctagtgtt ctagtgacac tgttttcact
     4981 acttgggacc cctatgacga caggaacagt catctatacg gcagtctggc agggattagg
     5041 aaatgcacgc ctcccttttt atgcgacaag tataggaatg tggtgtatcc gcattgggac
     5101 aggatatctg atggggattg tgcttggttg gggcttgcct ggtatttggg cagggtctct
     5161 cttggataat ggttttcgct ggttatttct acgctatcgt taccagcgct atatgagctt
     5221 gaaaggatag gaaatgcaaa aaacagcttt tatttgggat ttagacggga ctttattgga
     5281 ctcttacgaa gcgattttat cagggattga ggagactttt gctcagtttt ctattcctta
     5341 tgataaggag aaggtgagag agtttatctt caagtattcg gtgcaagatt tgcttgtgcg
     5401 ggtggcagaa gatagaaatc tggatgttga ggtgctaaat caggtgcgtg cccagagtct
     5461 ggctgagaag aatgctcagg tagttttgat gccaggtgcg cgtgaggtgc tagcttgggc
     5521 agacgaatca ggaattcagc agtttatata tactcataag gggaacaacg cttttaccat
     5581 tctcaaggac ttgggggtgg aatcctattt taaagagatt ttaaccagtc agagtggctt
     5641 tgtgcggaag ccaagtccag aagccaagtc cagaagcggc tacctatctg ctagataagt
     5701 atcagttgaa ttctgataat acttattata taggggatcg gactctggat gtggaatttg
     5761 cccagaatag tgggattcaa agcatcaact ttttagagtc tacttatgaa gggaatcaca
     5821 ggattcaagc gttagcagat atttcccgta tttttgagac taagtgataa aaagattgtg
     5881 tcagttttgt gacagagacc taacaaacta tttcaagtaa cctagtttgt tacaaggaat
     5941 agacagttct gttaaatagg cccgagaggg ctttttttct acattttttg tgttatgata
     6001 gacaggtact catttgaaag gaatttgaaa gaatgaagaa aagaatgtta ttagcgtcaa
     6061 cagtagcctt gtcatttgcc ccagtattgg caactcaagc agaagaagtt ctttggactg
     6121 cacgtagtgt tgagcaaatc caaaacgatt tgactaaaac ggacaacaaa acaagttata
     6181 ccgtacagta tggtgatact ttgagcacca ttgcagaagc cttgggtgta gatgtcacag
     6241 tgcttgcgaa tctgaacaaa atcactaata tggacttgat tttcccagaa actgttttga
     6301 caacgactgt caatgaagca gaagaagtaa cagaagttga aatccaaaca cctcaagcag
     6361 actctagtga agaagtgaca actgcgacag cagatttgac cactaatcaa gtgaccgttg
     6421 atgatcaaac tgttcaggtt gcagaccttt ctcaaccaat tgcagaagtt acaaagacag
     6481 tgattgcttc tgaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacga
     6541 ccgaaacaac tcgcccagtt gaagaagcaa ctcctcagga aacgactcca gctgagaagc
     6601 aggaaacaca agcaagccct caagctgcat cagcagtgga agtaactaca acaagttcag
     6661 aagcaaaaga agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag
     6721 aagagacgaa aataatttca acaacttacg aggctccagc tgcgcccgat tatgctggac
     6781 ttgcagtagc aaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc tttaaagaag
     6841 aaattgctaa cttgtttggc attacatcct ttagtggtta tcgtccagga gacagtggag
     6901 atcacggaaa aggtttggct atcgacttta tggtaccaga acgttcagaa ttaggggata
     6961 agattgcgga atatgctatt caaaatatgg ccagccgtgg cattagttac atcatctgga
     7021 aacaacgttt ctatgctcca ttcgatagca aatatgggcc agctaacact tggaacccaa
     7081 tgccagaccg tggtagtgtg acagaaaatc actatgatca cgttcacgtt tcaatgaatg
     7141 gataaacccg acttgataac atcattttga cgaatgagat ctagctttcg tgatggaaag
     7201 cgattctcgt tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa ccacgtcagt
     7261 tttatctgaa acttcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctt
     7321 tttgattttc attgagtatc aatttgaatg gaaaatggaa agttatcatc ttgtaatgag
     7381 ttaagcaaca ttcttgcaat ctattttact ttatatcaca attaattagt caaatattga
     7441 taaatcaata aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc
     7501 cgcttgtctg agcaagcgag tacgcaattg tttgaaaaaa ggcttgggat tagtttgaca
     7561 cggtatcaga ttttactgtt tttgctggag cattctcctt gtaaccaaat ggcggttcag
     7621 gagcgtttga aaattgatca ggctgctttg acacggcatt tcaaaatttt ggaaacggaa
     7681 ggtttggtgg agcgtcatcg taatcctgaa aatcagcggg aagtgttggt agaggctgcg
     7741 aagtatgcca aggagcagtt agtggtgaat ccccctctgc aacatatcag ggttaaggaa
     7801 gagatagaaa gtatcttaac agagtttgag agaacagaac tcagccgttt attaaataaa
     7861 ttggttttgg gtattgaaaa tatagaaatt taaggagaaa tagatgtcaa ttattttaac
     7921 aacgatcgtt gctttggagc atttttacat tttttatttg gaaagtattg ccacgcaatc
     7981 agatgcgact agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag
     8041 tttattgtta aaaaatcaag ggatttataa ggctctgcta ggagtctttc tcttgtatgg
     8101 catttatttc tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc
     8161 tgcgacttac ggctctttaa cagcggataa aaaaattatt ttgaagcaag gtggatcagc
     8221 tattttggcc ttgattagta ttttactctt taaatacact tgaaggtcga ttctaatctc
     8281 gctaatcctt ttcaatccag aataagggaa atatgttata cttgttttta agaaaaaagt
     8341 ctcattgaat tggttttgag gagttagaaa tgaaagtatt agtgacaggt tttgagccct
     8401 ttggagggga aaagggcaat ccagctttgg aggccattaa aggtttacca gctgaaatcc
     8461 atggtgctga ggtccgttgg ctagaggtgc cgacagtttt tcacaaatct gctcaagtat
     8521 tggaagaaga gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg
     8581 gaagaactag tttgacacct gaacgagtgg tcattaatca agacgatgca cgcatttctg
     8641 ataacgaaga taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact
     8701 ttagtagttt gccgattaaa gcgatggttc aagctataaa aaagaaggat taccggcctc
     8761 tgtttccaat acggcaggga cttttgtctg cagccatttg atgtatcagg ctctctattt
     8821 ggtagaaaag aaatttccat atgttaaggc aggttttatg catattcctt atatgatgga
     8881 acaggtggtg aacagaccga ctactccaac tatgagttta gtggatattc ggcgagggat
     8941 agaagcagca atcggcgcta tgatagaaca tggagatcag gaactcaagt tggtaggcgg
     9001 agaaactcat tgatagaaaa aagcttgagg ggaaaaacct tcaagctttt ggacgttttc
     9061 gagccaatac tgctcggtaa aacataattt tagtgcattg gatataaggt aggagtgaaa
     9121 aactagcaat gccaaaggta atccaattga ggaagtacca aggaagaagc tgtaaatcta
     9181 ggacaaagcg ctggaacttg tagcccttca taaaggaacg gctagttttt aggattcgtc
     9241 ttggtgggac ctgtcctagg tctaaactat aacagagaag aaattccacc tgtgaatagg
     9301 cataatactg tggaatatag aggatatttc ctacaatgat caagatgaga cttgcaagaa
     9361 agtagagtcc aaagaccatg aggaaacgct cggtttcaac tgatgagaga tctagatttg
     9421 gaaactcagg atgtagggtg acgaattttt tggctaaaaa gctactataa aagaggaggt
     9481 aaatcccaag taaattaggg atactccata aaaagagata gaaacgtttg agaagtaggg
     9541 tcaaaaaggt ttgagaaaag cgctcctcat caaagagagc taggctgttt tttacagatg
     9601 gctccgtttt agaatctttc atgagtgtca gtgttgcata gacggaactg gtcaaaagaa
     9661 tagtcccgat aaaggagact agtagaggaa agaggtaggc ttgaagtatt tggccaagta
     9721 tgctgaaaaa tggctgttct aaaacagtcc cgtggatccg agataaggga ttaagaaaac
     9781 cagataagat gaccagcata ctgggaagga tatagaggag aaagagacgg ggggtgtcag
     9841 cctgaaaatg ttttgactcc tgacgaattg tttttaaatc aatttttgga tagttcattc
     9901 tcttattata ccatagttct tatacatagt tcgtgacagt tcctactttt tttgataaaa
     9961 tcatacagtg tgtccttggg cacactgtat gaactgggac tgtctttccc agcttcggag
    10021 gtaaaaaatg tcagattcac caatcaaata tcgtttgatt aagaaagaaa aacacacagg
    10081 agctcgtcta ggagaaatca tcactcccca cggtaccttt ccgacaccta tgtttatgcc
    10141 agttgggaca caagccactg tcaaaactca gtcacctgaa gaattgaagg agatgggttc
    10201 gggaattatc ctatcaaaca cctatcatct ctggcttcgc cctggagatg aactcattgc
    10261 acgcgctggt ggtctccaca agttcatgaa ttgggaccag cctatcttga cagatagtgg
    10321 tggttttcag gtttattctt tagcagatag ccgtaatatc acagaagaag gagtaacctt
    10381 taaaaatcat ctaaatggtt ctaagatgtt cctatcccca gaaaaagcca tctctattca
    10441 gaataatctg ggttcagaca tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc
    10501 ttatgactac gttaagaaat cgatcgagcg taccagccgt tgggctgagc gtggtttgaa
    10561 ggctcaccgt cgtccacatg accaaggttt gtttggaatt gtgcaaggtg caggatttga
    10621 agaccttcgc cgccaatcag ctcatgatct tgtcagcatg gatttctcag gctactctat
    10681 cggtggtttg gcagtgggag aaacccatga agagatgaat gcggtcttgg actttacaac
    10741 tcaactgctg cctgaaaata aacctcgtta tctgatgggt gtgggagcgc cagatagctt
    10801 gatcgatggg gtcattcgtg gggtggatat gtttgactgt gtcttaccga ctcgaattgc
    10861 tcgtaacggg acttgtatga ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc
    10921 tgaggacttt acgccactgg atcctgagtg tgattgctac acatgtaata actatacacg
    10981 cgcttacctt cgtcacctgc tcaaggctga tgaaaccttt ggtatccgct tgactagcta
    11041 ccacaatctt tacttcttgc ttaacctgat gaagcaagtg cgacaagcca tcatggatga
    11101 caatctcttg gaattccgta agtattttgt ggaaaaatat ggctataata agtcaggacg
    11161 taatttctaa aatggaattg atataagcta aaaatcctaa gttttctctt aggatttttc
    11221 ttcttttttt gatagaataa agtgtacaat gaaaggaaga ataaactcgt atgcgcatta
    11281 aatggttttc cttggttagg attacaggtt tacttttggt actcttgtat cacttctttc
    11341 agacgatctt tcctggagga ttcttcgggg tagatgtctt tttcacattt tcaggtttcc
    11401 tgattacagc tctactcatt gaagaatttt ctaagaacaa tgagattgat ttgataggat
    11461 tttttagaag acgcttttat cggattgtgc cacctgtggt tttgatggtc ttggtgacca
    11521 tgccttttac tttcttggtt cgccaagact atgttgctgg aattggtggc cagattgcgg
    11581 gcgtcttagg ctttatgacc aacttctatg aactcctaac aggtgggagt tatgaatctc
    11641 agttcattcc tcatttgttt gttcataatt ggagtttggc agttgaggtt cactactata
    11701 ttctttgggg attggcagtt tggttcttat ccaaacaagc taaatcaaat ggtcagttga
    11761 aggggatggt ctttctctta tctgctgctg ccttcttgat cagtttcttc tccatgttta
    11821 ttggtagttt tctagtgacc tcttattcct ctgtttattt ctccagttta actcatgtct
    11881 atccattctt tttgggaagt atgttagcaa ctattgtagg cgttcgtcag acgacttccc
    11941 tcgtcaagca gttggataaa atctgggatt tacgaaagac tttggtagtt tttggaggag
    12001 gctttggttt cctagttctt ttgactttct ttgtcaaatt cacttatctt tttgcctatc
    12061 ttatcggctt cttgcttgcc agtcttgcag ctcttgccat gattctggcg gcgcgtgtct
    12121 tacatgaaaa gacacatcat atacaggagc cgaagattat cagcttttta gcggatacta
    12181 gctatgcggt ttatcttttc cattggcctt tctatatcat tttctcacag ttgacatcaa
    12241 atcttcttgc tgtattactg actctgattt gttcttatgg ctttgccagt ctgtcattct
    12301 atgtattgga accttggatt gcaggcaaga acacacctat tttacaaact cttcgtcccc
    12361 tgccttatat tcacgcaatt cttgcagcag gtacaggaat cttgaccttc attgtctgca
    12421 tggtgacctt gttggcacca caagtgggag cgtttgagac agacttgact gttaatggct
    12481 tgaagcaagc tgcaacaaat attggccaga ccaaggtgat ggcagaacgg gcagatgcaa
    12541 acagtttggg aattgctgat ggcactatgt taattggtga ctcagtggct ttaagggcaa
    12601 atacagcact acagacagct cttcctggag cacagattaa cgcgcaggtc agcgtaacaa
    12661 ccaagactgc aaatgaaatc atgctaaata atagccagaa taaattttta cctaagacgg
    12721 tggtcattgc gactggggta aataatcctg agaattacaa ggatgactgg gacagtatcg
    12781 tgaaaaatct tcctaaggga caccgtatga ttttggtgac tccttatgag ggagataaga
    12841 caaaagagac ctatgccatc gttgagaagg ctgctgccta tatgagagaa ttggcagaga
    12901 agacacctta cattacgata gcagattgga atcaagttgc gaaagagcat ccagaaattt
    12961 gggctggaac agaccaggtt catttcggga gtgagagtag cactatcgaa gcaggagcaa
    13021 aattgtatgc agatacgatt gccacagctt tgcagacagc tcaagataag ccggttaaat
    13081 caaaataact tgtattaaaa aagagaagag ttggagaaat ccagctcttt taaaatatct
    13141 ccaaaaaata ggtctatacc atttacaaat aaaaaagaaa ggtttataat gtaattgaca
    13201 taataaattg tagaatcaat cttttaagga ggttaacatt atgcctaact atattaaagc
    13261 ggatcagttt ttctacccac acggagttcg tcgaggtggt tacttggaac ttgtggacgg
    13321 caagtttgga aaacatgtag agcagattcc tgaaggggct gaggtgattg actatacagg
    13381 ttatagcatt gccccaggtc ttgtggatac tcatattcat ggatatgcag gtgtagatgt
    13441 gatggacaac aacattgaag gtacattgca tactatgagt gaaggacttc ttagtaccgg
    13501 tgttaccagt ttcttaccca caactttaac agccacttat gagcaattgc ttgcagtcac
    13561 tgaaaatctt ggaaaccatt ataaagaagc aacaggtgct aagattcgtg ggatttatta
    13621 tgaaggtcca tatttcacag aaacttttag gggggcacaa aatccaactt atatgagaga
    13681 cccgggtgtt gaggagtttc attcttggca aaaagcggca aatggcttgc ttaataaaat
    13741 tgcccttgca ccagaacgtg atggggtgga agactttgtt cgtacagtta cgggcgaagg
    13801 tgtgacggtt gctcttggac attcaaacgc gacttttgat gaagccaaaa aagcagtcga
    13861 tgctggagcg agtgtttggg tgcatgccta caatggaatg cgtgggttga ctcaccgtga
    13921 attgggtatg gttggagcca tgtaccaatt gccacatacc tatgcagagt tgatctgtga
    13981 tggtcaccac gtagatccaa aggcttgcga aattcttatc aaacaaaaag gaacagaaaa
    14041 catcgctctt atcacagact gtatgacagc tgggggattg gaagacggag attatatgtt
    14101 gggagaattc ccagttgtcg ttgcaaatgg aactgcacgc ctcaaatcga caggtaactt
    14161 ggcaggttct atcctcaaac tcaaagatgg tttgaagaat gtggtcgaat ggggaattgc
    14221 gaatccgcat gaagcagtca tgatggccag cttcaaccca gctaaatccg ttcacatcga
    14281 tgacgtctgt ggccaaatcc gtgaaggcta cgacgctgac ttcatcgtat tagataaaga
    14341 tttggaattg gtagcaacct acctagatgg tgtgaaacgt tatcaagcat aagagagaag
    14401 gcagaagtta gagactagct tctgcttttt tatacagggt actttactgg taaataaaaa
    14461 gttaaaaaaa tcacaaaaaa agcttgaaga aacaaagaaa aaggcttaca attgaactat
    14521 aaatattaca aataaaaaaa cggaggagtg ctttatgaaa gcctatactt atgttaaacc
    14581 aggacttgct tcttttgttg atgtagacaa accagttatt cgcaagccaa cagatgctat
    14641 tgtgcgtatt gtaaaaacca ctatttgtgg aacagacctc catattatca aaggggatgt
    14701 tcctacttgc caaagtggta ccattcttgg ccacgaagga attgggattg ttgaagaagt
    14761 tggggaagga gtttccaact tcaaaaaagg tgacaaggtc ttgatttctt gcgtctgtgc
    14821 ctgtggtaaa tgctactact gtaaaaaagg aatttatgcc cactgtgaag acgaaggggg
    14881 ctggattttc ggtcacttga ttgatggtat gcaggctgaa tatctacgtg tccctcatgc
    14941 agataatact ctttaccata ctccagaaga cttgtcagat gaagctttgg ttatgctgtc
    15001 agacattctg cctactggat atgaaattgg tgtcttaaaa gggaaagtag aacctggttg
    15061 cagcgtagcc attattggtt caggtccagt tggattggct gctcttttaa cagcccaatt
    15121 ctattcacca gctaaattga ttatggtgga cttggatgat aaccgtttgg atactgccct
    15181 atcattcggt gctactcata aggtaaactc ttcagaccct gaaaaagcga taaaagaaat
    15241 ttatgatttg acagatggtc gcggtgtaga tgtcgctatt gaagctgtag ggattcctga
    15301 aacatttgat ttctgtcaaa agattatcgg tgtagacgga acggttgcca actgtggtgt
    15361 gcatggtaaa ccagttgaat tcgatttaga taaactttgg attcgcaaca tcaatgtaac
    15421 aactggtttg gtatctacaa atacgactcc acaattgttg aaagcacttg aaagtcataa
    15481 gattgaacca gaaaaattgg taactcacta tttcaaactc agtgaaattg aaaaagccta
    15541 cgaagtcttc agtaaggcag cagaccacca tgccattaag gtcattatcg aaaacgatat
    15601 ctcagaagcc taagtagtaa aaatattttt gtacataagt aaatagaaat tcagtcatcc
    15661 atcagatggt tggatttttt atcaaaaaat taagaaatga gcatatttct ttccttgtct
    15721 ggcggaattg gttataatat acggtacaaa ggaatgaatg aatatgtatc gtgttataga
    15781 aatgtacgga gattttgaac cgtggtggtt cttagaaggt tgggaagaag atattgtagc
    15841 aagtagaaaa tttgaccagt attatgatgc tctcaaatac tacaaaactt gctggtttag
    15901 attggaacaa gaatcgcctc tttataaaag tagaagcgac ttgatgacca ttttttggga
    15961 cccggaagac caacgctggt gtgatgaatg tgatgagtat ttacaacaat accattcttt
    16021 ggctcttttg caggatgagc aggttatccc agacgaaaaa ctacgctcag gctatgaaaa
    16081 acaaaccagt caggaaagga atcgttcttg ccgtatgaaa ttaaaataga gaaaagtaac
    16141 ttttttggag ttgctttttt tatttttcta actctttgcg aatagtatag gtgaggaggt
    16201 aagtatggtt caagaaattg cacaagaaat cattcgttca gctcggaaaa aagggacgca
    16261 ggatatttat tttgtcccta agttagatgc ctatgagctt catatgaggg taggagacga
    16321 gcgctgtaaa attggtagct atgattttga aaagtttgca gccgttatca gtcactttaa
    16381 gtttgtggcg ggtatgaatg tgggagaaaa aagacgtagt caactgggtt cctgtgatta
    16441 tgcctatgac cagaagatgg cgtctctacg tttatctact gtaggcgatt atcgggggca
    16501 tgagagtttg gttatccgtt tgttgcacga tgaggagcag gacttgcatt tttggtttca
    16561 ggatattgaa gaattaggca agcagtacag gcaacgggga ctctatcttt ttgctggtcc
    16621 ggttgggagt ggtaagacga ccttgatgca tgaattgtcc aagtcactct ttaaaggaca
    16681 gcaagttatg tccatcgaag atcctgtcga aatcaagcag gacgacatgc ttcagttgca
    16741 gttgaacgaa gcaatcggcc taacctatga aaatctaatc aaactttcct tgcgtcatcg
    16801 accagatctc ttgattatcg gagaaattcg tgacagcgag acggcgcgtg cagtggtcag
    16861 agctagtttg acaggtgcga cagtcttttc aaccatttac gccaagagta tccgaggtgt
    16921 ttatgagcgt ctgctggagt tgggtgtgag tgaagaagaa ttggcagttg ttctgcaagg
    16981 agtctgctac cagagattaa tcgggggagg aggaatcgtt gactttgcaa acagagatta
    17041 tcaagaacac caagcagtca agtggaatga gcaaattgac cagcttctta aagatggaca
    17101 tatcacaagt cttcaggctg agacggaaaa aattagctac agctaagcaa aaaaatatca
    17161 tcaccctatt taacaatttc ttttctagcg gttttcatct ggtggagacc atctcctttt
    17221 tagataggag tgctttgttg gacaagcagt gtgtgacccg gatgcgtgtg ggcttgtctc
    17281 aggggaaatc attctcagaa atgatggaaa gtttgggatg ttcaagtgct attgtcactc
    17341 agttatccct agctgaagtt catggcaatc tccacctgag tttgggaaag atagaagaat
    17401 atctggacaa tctggccaag gtcaagaaaa aattgattga agtagcgacc tatcccttga
    17461 ttttgctgtt ttttcttctc ttaatcatgc tggggctacg gaattacctg ctcccacaac
    17521 tggatagtag caatattgcc acccgaatta tcggtaatct gccacaaatt tttctaggca
    17581 tggtagggct tgtttccgtg cttgcccttt tagcactaac tttttataaa agaagttcta
    17641 agatgagtgt cttttctatc ttagcacgcc ttccctttat tggaatattt gtgcagacct
    17701 acttgacagc ctattatgca cgtgaatggg ggaatatgat ttcacaggga atggagctga
    17761 cgcagatttt tcaaatgatg caggaacaag gttcccagct ctttaaagaa atcggtcaag
    17821 atctggctca aaccctgaaa aatggccgtg aattttctca gacgatagga acctatcctt
    17881 tctttaggaa ggaattgagt ctcatcatag agtatgggga agttaagtcc aagctgggta
    17941 gtgagttgga aatctatgct gaaaaaactt gggaagcctt ttttacccga gtcaaccgca
    18001 ccatgaattt ggtgcagcca ctggttttta tttttgtggc actgattatc gttttacttt
    18061 atgcggcaat gctcatgccc atgtatcaaa atatggaggt aaatttttaa aatgaaaaaa
    18121 atgatgacat tcttgaaaaa agctaaggtt aaagctttta cattggtgga aatgttggtg
    18181 gtcttgctga ttatcagcgt gcttttcttg ctctttgtac ctaatctgac caagcaaaaa
    18241 gaagcagtca atgacaaagg aaaagcagct gttgttaagg tggtggaaag ccaggcagaa
    18301 ctttatagct tggaaaagaa tgaagatgct agcctaagaa agttacaaga cgatggacgc
    18361 atcacggaag aacaggctaa agcctataaa gaataccatg ataaacaaaa tactagtcaa
    18421 atcgttaaag attaaggcct ttaccatgct ggaaagtctc ttggttttgg gacttgtgag
    18481 tatccttgcc ttgggcttgt ccggctctgt ccagtccact tttgcagcgg tagaggaaca
    18541 gattttcttt atggagtttg aagaactcta tcgggaaacc caaaaacgca gtgtagctag
    18601 tcaacaaaag actagtctga acttggatgg gcagatgatt agcaatggca gtcaaaagtt
    18661 gccagtccct aaaggaattc aggccccatc aggccaaagt attacatttg accgtgctgg
    18721 gggcaattcg tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca
    18781 attatatcta ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga
    18841 ttttactgga agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg
    18901 gacaaattca aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga
    18961 gggtagctaa gatggccttg cagacggggc aaaatcaggt aagcatcaac ggagttgaga
    19021 ttcaggtatt ttctagtgaa aaaggattgg aggtctacca tggttcagaa cagttgttgg
    19081 caatcaaaga gccataaggt caaggctttt accttgttag aatccctgat tgccctgatt
    19141 gtcatcagtg ggggattact cctttttcaa gctatgagtc agctcctcat ttcagaagtt
    19201 cgctaccagc aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggca
    19261 gaattagacc gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat
    19321 ggcaaggaga ttgctatggg taagtctaag gcagatgatt tccgtaaaac gaatgctcgt
    19381 ggtcgaggtt atcagcctat ggtttatggc ctcaaatcag ctcagattac agaggacaat
    19441 caactggttc attttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt
    19501 gtggaaaaag aagaaagtta aggcaggtgt tctcctctac gcagtcacca tagcagccat
    19561 ctttagtctt ttgttacaat tttacttgaa ccgacaaatc gcccactatc aagactatgc
    19621 tttaaataaa gaaaagttgg ttgcttttgc catggccaag cgaaccaagg ataaagccga
    19681 gcaagaaagt ggggaacagg tttttaatct aggtcaggta agctatcaaa acaagaaaac
    19741 aagcttggtg acgactgttc gtacggataa gagtcaatat gagtttctgt ttccttcagt
    19801 caaaatcaaa gaagagaaaa gagataaaaa ggaagaggta gcgactgatt caagcgaaaa
    19861 agcggagaag aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca
    19921 actataatgt gttgaatcca gaatagtcca ctgtagtttc tagaaacgcg aaaggttctc
    19981 ttaatcaatc caatataaag gcaaggagta gtgaatacga aacaaatttt aaaattttta
    20041 aaattgaagt ttggctttta acatgagggg tttcccttca ccaaatttga gtctgcctat
    20101 cccttgacta ttctttcctt tcacaaacga gtcgcttatt caattataag tttacgtgct
    20161 cctagtcaca gttcttgtgc ttgatggaaa gaatgacacc tataaaaatg cgaggtagtg
    20221 gctataccac tcacttattc acctccccgt gatttgtagt agtgataggt tttctcacta
    20281 ttattataaa acaaaataaa gagcacacca ctttttcatt ctgtcttgtg ccttgagtga
    20341 aacgaaagga atgaattata aacataaaag tttagtatat agattatttc tctcaaaata
    20401 tgcaaataag atagaatata gtggattgaa tctggaatag tccgccgagt tttctaaaac
    20461 attgttagaa attggtttga attctgcaat caatttattc acatcttatt tcaacatgtt
    20521 ataaatttat agcagactta gagaaaagca gaaactagta tcattactag tttctgcttt
    20581 tctccataat aattaatttc cccctttttc cttctaaatc ttttttcaca acagaaaaac
    20641 cggaatttct atatgctttt tgagccaata tatttttttc atttacagcc aatataatat
    20701 ggttaatttc taattttaaa gttgagtcta tgaattcaaa tatttcattc agagcattag
    20761 aaccatatcc ttgatttctg aaattatcat gaatagaaaa tcctctaata agcgcataat
    20821 cattttgata atagccatac tctttaggac cagtgtttag gtgtaggcaa aaaaatccaa
    20881 ttactttatg gtctttatta agtattacta ttgggtatct atacttatct tttttagact
    20941 tttcaataat attttttggg gtatcagtat atgtaatatc atttaaagaa taagaactta
    21001 aaaaatggta atgttcaact tcactataca a
//
LOCUS       DAVHSI010000034        20580 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.034, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000034 DAVHSI010000000
VERSION     DAVHSI010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20580
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.034"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(1..733)
                     /locus_tag="VVR21_001527"
                     /pseudo
     CDS             complement(1..733)
                     /locus_tag="VVR21_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; incomplete;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1079..2032
                     /locus_tag="VVR21_001528"
     CDS             1079..2032
                     /locus_tag="VVR21_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6055374.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLAKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANANQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            2083..3273
                     /locus_tag="VVR21_001529"
     CDS             2083..3273
                     /locus_tag="VVR21_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU6055375.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISHVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            3422..3793
                     /gene="rnpA"
                     /locus_tag="VVR21_001530"
     CDS             3422..3793
                     /gene="rnpA"
                     /locus_tag="VVR21_001530"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU6055376.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKKHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3768..4592
                     /locus_tag="VVR21_001531"
     CDS             3768..4592
                     /locus_tag="VVR21_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU6055377.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKSVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            4611..5597
                     /locus_tag="VVR21_001532"
     CDS             4611..5597
                     /locus_tag="VVR21_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU6055378.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            5648..6271
                     /locus_tag="VVR21_001533"
     CDS             5648..6271
                     /locus_tag="VVR21_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU6055379.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELVKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQANILDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            6402..7859
                     /locus_tag="VVR21_001534"
     CDS             6402..7859
                     /locus_tag="VVR21_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU6055380.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7882..8163
                     /locus_tag="VVR21_001535"
     CDS             7882..8163
                     /locus_tag="VVR21_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6055381.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            8241..8726
                     /locus_tag="VVR21_001536"
     CDS             8241..8726
                     /locus_tag="VVR21_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6055382.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8743..9408
                     /locus_tag="VVR21_001537"
     CDS             8743..9408
                     /locus_tag="VVR21_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU6055383.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIRR
                     IWG"
     gene            9412..10275
                     /locus_tag="VVR21_001538"
     CDS             9412..10275
                     /locus_tag="VVR21_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU6055384.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKELDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            10277..10981
                     /locus_tag="VVR21_001539"
     CDS             10277..10981
                     /locus_tag="VVR21_001539"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU6055385.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            11158..12831
                     /locus_tag="VVR21_001540"
                     /pseudo
     CDS             11158..12831
                     /locus_tag="VVR21_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
     gene            12943..14034
                     /gene="ulaG"
                     /locus_tag="VVR21_001541"
     CDS             12943..14034
                     /gene="ulaG"
                     /locus_tag="VVR21_001541"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU6055386.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            14148..16130
                     /gene="tkt"
                     /locus_tag="VVR21_001542"
     CDS             14148..16130
                     /gene="tkt"
                     /locus_tag="VVR21_001542"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU6055387.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVAAAKEL
                     ASKGEKVRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLKQS"
     gene            16241..16540
                     /gene="yajC"
                     /locus_tag="VVR21_001543"
     CDS             16241..16540
                     /gene="yajC"
                     /locus_tag="VVR21_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU6055388.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            16587..17015
                     /locus_tag="VVR21_001544"
     CDS             16587..17015
                     /locus_tag="VVR21_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU6055389.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            17017..17427
                     /locus_tag="VVR21_001545"
     CDS             17017..17427
                     /locus_tag="VVR21_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055390.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17727..20378
                     /gene="adhE"
                     /locus_tag="VVR21_001546"
                     /gene_synonym="adhC"
     CDS             17727..20378
                     /gene="adhE"
                     /locus_tag="VVR21_001546"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU6055391.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         6430 a         3717 c         4443 g         5990 t
ORIGIN      
        1 tttcgatagg ttgttgaaaa cattttaaac gtttttactt tggcaaagat gttctcaacc
       61 ttgcttctcc cttagatagc gcatggttac aggctttatc ttcagctgtt agcggcttga
      121 gtttgctgga tttacgtgga gtttgtgctt gaggatatat cttcatgagc ccttgataac
      181 cactgtcggc caagatttta ccagcttgtc cgatatttct gcgactcatt ttgaacaact
      241 tcatatcatg acaatagttc acagcgatat ccaaagaaac aattctccct tgacttgtga
      301 caatcgcttg aggttccata gaatgacatt tctattttac cagaataatt ggctagttga
      361 tttttttagg acgatttatt tttacctctg ttgcatccac aatcaccgta ttctcagcac
      421 taagatgagt tcttgaaatc gtaacaccac tttgaacaag agttacttca acccattggc
      481 tccgacggag taagttgctt tcgtggatac caaaaacagc cgcaatttct tcataagttc
      541 gatattctcg cacatattga agagtggcca taagaaggtc ttctaggctt aatttaggtt
      601 ttcgtccacc ttttgcgtgt ttaagttgat aagctgtttt taatacagct aacatctctt
      661 taaaagtcgt gcgctgaaca ccaacaagac gcttaaattg tgcattggtt agttgtttac
      721 tttcttcata aattttattg tatcatattt ttgtttcaca ggaagtctaa taaataaaaa
      781 ttctttaaaa ttttgttggg aaaatgggaa aagatataaa tggaaactta gtataacact
      841 tggaaaactc tgtaaaaata gtaagtcaat tcatgtcccg ttttttctct agggaagttg
      901 ggcggctata tttatatgac catttgtcgt aataaacatc cctaccaagg gtcaatagaa
      961 ataaattcaa cgaaactttt gctgtcagat ttagatgccc aatttgtcat ttatactctt
     1021 tcatatagga ctttctataa ggatggaaaa aagaagggaa atttgataag ataggaatat
     1081 ggattttgaa aaaattgaac aagcctatac ctatttacta gagaatgtcc aagtcatcca
     1141 aagtgatttg gcgaccaact tttatgacgc cttggtggag caaaacagca tctatctgga
     1201 tggtgaaact gagctaaacc aggtcaaaga caacaatcag gcccttaagc gtttagcact
     1261 acgcaaagaa gaatggctca agacctacca gtttctcttg atgaaggctg gacaaacaga
     1321 acccttgcag gccaatcacc agtttacgcc agatgctatt gccttacttt tggtatttat
     1381 tgtggaagag ttgtttacag aggaggaaat cactatcctt gaaatgggtt ctgggatggg
     1441 aattctaggc gctactttct taacctcgct tgctaaaaaa gtggattact tgggaatgga
     1501 aatggatgat ttgctgattg atttggcagc tagtatggca gatgtaattg gtttgcaggc
     1561 tggctttgtc caaggagatg ccgttcgtcc acaaatgctc aaagaaagcg atgtggtcat
     1621 cagtgacttg cctgttggct attatcctga tgatgccgtt gcgtcgcgcc atcaagttgc
     1681 ttctagccaa gaacatactt acgcccatca cttgctcatg gaacaagggc ttaagtacct
     1741 caagtcagac ggatacgcta tttttctagc tccgagtgat ttgttgacca gtcctcaaag
     1801 tgatttgtta aaagaatggc tgaaagaaga ggcgagtctg gttgctatga ttagtctgcc
     1861 tgaaaatctc tttgctaatg ccaaccaatc taagactatt tttatcctac agaagaaaaa
     1921 tgaaatagca gtagagcctt ttgtttatcc acttgctagc ttgcaagatg caagtgtttt
     1981 aatgaaattt aaagaaaatt ttcaaaaatg gactcaaggt actgaaatat aaaatagatt
     2041 ttgttataat agttgaaaac gcttaaaaag gggtatcatg ttatgacaaa aacaattgca
     2101 atcaatgcag gaagttcaag tttgaaatgg caattatact taatgccaga agaaaaagta
     2161 ttggcgaaag gtttgattga acgtatcggt ttgaaagatt caatttcaac tgtaaaattt
     2221 gacggccgtt ctgaacaaca aattttggat atcgaaaatc atacacaagc tgttaaaatt
     2281 ttattggatg acttgattcg tttcgatatt atcaaggctt atgacgagat tacaggtgtt
     2341 ggccaccgtg ttgtagcagg tggagaatat ttcaaagaat caacagttgt tgagggagat
     2401 gttttagaaa aagttgaaga gttgagtttg ttggctcctc tacacaaccc ggccaatgca
     2461 gcaggtgttc gtgccttcaa ggaattgttg ccagacatta ccagtgtagt tgtttttgat
     2521 acttccttcc acacaagtat gccagagaaa gcttatcgct accctctacc aacaaaatat
     2581 tacacagaaa acaaggttcg taaatacggt gctcatggta caagtcacca gtttgtagca
     2641 ggagaagctg caaaactctt gggacgtcca ttagaagact tgaagttaat tacctgtcat
     2701 attggtaacg gaggctcaat tacagctgtg aaagccggca aatctgtaga cacttctatg
     2761 gggttcactc ctcttggtgg tattatgatg ggaacgcgta caggggatat tgatccagct
     2821 atcattcctt atttaatgca atatacagag gattttaaca caccagaaga tatcagtcat
     2881 gttcttaacc gtgaatcagg tcttttggga gtttctgcta attctagcga tatgcgcgat
     2941 atagaagcag ctgtagcaga agggaatcac gaggctagct tggcttatga aatgtatgtt
     3001 gaccgtatcc aaaaatatat cggtcagtac cttgcagtgc taaatggagc agatgccatt
     3061 gttttcacag caggtgtcgg tgaaaatgca gagaatttcc gtcgtgatgt aatctcaggg
     3121 atttcgtggt ttggttgtga tgttgatgat gaaaagaatg tctttggcgt tacaggagac
     3181 atctcaacag aggcagctaa aatccgtgtc ttggttattc caacagatga agaattagtc
     3241 attgcccgtg acgttgaacg cttgaaaaaa taagtgaaac taaaaaaata ttcaatacaa
     3301 ggagttggga aagttatttt tccagcttct ttttctgatg aaattgtcca aaaccttgct
     3361 atgattggct tttttgaaaa atatggtata atagtagtaa tttaatagat ggagttgagt
     3421 tttgaagaaa aactttcgtg taaaaagaga gaaagatttt aaggcgattt tcaaggaggg
     3481 gacaagtttt gctaatcgca aatttgtggt ctaccaatta gaaaaccaga aaaaacattt
     3541 tcgagtaggt ctatcagtta gcaaaaaact ggggaatgcc gtcactagaa atcaaattaa
     3601 gcgacggatt cggcatatta tccagaatgc aaaagggagt ctggtagaag atgtcgactt
     3661 tgttgtcatt gctcgaaaag gagtcgaaac cttgggatac gcagagatgg agaaaaatct
     3721 actccatgta ttaaaattat caaagattta ccgggaagga aatgggagtg aaaaagaaac
     3781 taaagttgac tagtttgcta ggactgtctc tgttaatcat gacagcctgt gcgactaatg
     3841 gggtaactag cgatattaca gccgaatcgg ctgatttttg gagtaaatcg gtttacttct
     3901 ttgcggaaat cattcgcttt ttatcgtttg atattagtat cggagtgggg attattctct
     3961 ttacggtctt gattcgtaca gtcctcttgc cagtctttca ggtgcaaatg gtggcttcta
     4021 ggaaaatgca ggaagctcag ccacgcatta aggcgcttcg agaacaatat ccaggtcgag
     4081 atatggaaag cagaaccaaa ctagagcagg aaatgcgtaa agtatttaaa gaaatgggtg
     4141 tcagacagtc agactctctt tggccgattt tgattcagat gccggttatt ttggccctgt
     4201 tccaagccct atcaagagtt gactttttaa agacaggtca tttcttatgg attaaccttg
     4261 gtagtgtgga tacaaccctt gttcttccga ttttagcagc agtattcacc tttttaagta
     4321 cttggttgtc caacaaagct ttgtctgagc gaaatggcgc tacgactgcg atgatgtatg
     4381 ggattccagt cttgattttt atctttgcag tttatgcgcc aggtggagtc gccctatact
     4441 ggacagtgtc taatgcttat caagtcttgc aaacctattt cttgaataat ccattcaaga
     4501 ttatcgcaga gcgcgaggcc gtagtacagg cacaaaaaga tttggaaaat agaaaaagaa
     4561 aagccaagaa aaaggctcag aaaacgaaat aaataaggag gaatctggta atggtagtat
     4621 ttacaggttc aactgttgaa gaagcaatcc agaaaggatt gaaagaatta gatattccaa
     4681 gaatgaaggc tcatatcaaa gtcatttcta gggagaaaaa aggctttctt ggtctatttg
     4741 gtaaaaaacc agcccaagtg gatattgaag cgattagtga aacgactgtt gtcaaagcaa
     4801 atcaacaggt agtaaaaggc gttccgaaaa aaatcaatga tttgaacgag cctgtgaaga
     4861 cggttagtga agaaaccgtt gaccttggtc atgtggttaa tgctattaaa aaaatagagg
     4921 aagaaggtca aggtatttct gatgaagtca aggctgaaat cttaaaacat gaaagacatg
     4981 ccagcactat cttagaagaa actggtcaca ttgagatttt aaatgaactt caaatcgagg
     5041 aagcgatgag ggaagaagca ggcgctgatg accttgaaac tgagcaagat caaactgaaa
     5101 atcaagactt gaaagagatg ggcttgaagg tcgagcaaag ttatgatatt gcccaggtgg
     5161 ctacggatgt gactgcctat gttcaagcga ttgtggatga catggatgtt gaagctacac
     5221 tttcaaatga ttataaccgt cgtagcatca atctacaaat tgacaccaac gaaccaggtc
     5281 gtattatcgg ctaccatggt aaagtcttga aggccttgca actgttggct caaaattatc
     5341 tttacaaccg ctattccaaa accttctacg ttacaatcaa tgtcaatgat tatgttgaac
     5401 accgtgcaga agtcttgcag acctatgcgc aaaaattggc gattcgtgtt ttagaagaag
     5461 gacgtagtca tcaaacagat ccaatgtcga atagtgaacg caagattatc caccgtatta
     5521 tttcacgtat ggatggcgtg accagttact ctgaaggtga tgagccaaat cgctatgtcg
     5581 ttgtagatac agaataagta aaatcagggt tgacctgatt ttttgctagc tagaggaggt
     5641 taaactgatg ttgaataaga taagagacta tctagacttt tctggtttgc agtaccgtag
     5701 tcctgataaa gcgggagcag agcgagagaa gatgctggcg ttccgccaca aaggacaaga
     5761 ggcccgaaag gcttttacag aactggtcaa agcctttcaa gcaagccatc cagaatggca
     5821 actccaacag actagtcagt ggatgaatca ggcccagcgt ttgagaccac atttttgggt
     5881 ttatctacag agagacggac aagtgacaga acctatgatg gccttacgtt tgtatgggac
     5941 atctactgac tttggaattt ctttggaagt cagtttcatc gaacgtaaga aggatgagca
     6001 aacactgggc aagcaggcca atattttaga cattccaacc gttaaaggga tttattatct
     6061 aacctactct aatggtcaaa gtcaacggtg ggaggcgaat gaagaaaagc gtcgtacttt
     6121 acgcgagaag gtgagaagtc aagaagttcg aaaagtttta gtgaaggtag atgttcctat
     6181 gacagaaaat tcgtctgaag aagaaatcgt agaaggctta ttgaagtctt attctaaaat
     6241 tcttccctat tatctagcta cgagaaaata agataatttg taaaacatca taaatcatac
     6301 agtccaagag tgaacagtcc gctgtgtaat tcttggtctt tttgtttgcg ctttcgcatt
     6361 atataataaa cttacaaaaa caattcaaaa ggagaacaat tatggaagtc gtttcaagtg
     6421 ttctaaattg gttttctagc aatattttgc agaatcccgc atttttcgta ggtttattgg
     6481 tgttgatagg atatgcactt ttgaaaaaac ctgcccatga cgttttttca gggtttgtta
     6541 aagcaacagt agggtatatg ttgcttaacg tgggtgctgg tggtttggtt acaacctttc
     6601 gtccaatctt agcagctctt aactacaaat tccaaattgg tgcagcggtt atcgaccctt
     6661 actttggact tgctgcagca aacaacaaaa ttgcagcaga gtttccagat tttgttggaa
     6721 ctgcaactac agctctattg attggtttcg gaataaatat cttgctcgta gctcttcgaa
     6781 agattacgaa ggtaagaacc ctctttatta ctggtcacat catggtacaa caagctgcaa
     6841 cagtatctct tatggttcta ttcttagtac cacaattgcg caatgcttac ggtacagcag
     6901 cgattggtat catctgtgga ctttactggg cagttagttc aaatatgact gttgaggcaa
     6961 ctcaacgctt gactggtggt ggcggatttg cgattggtca ccaacagcaa tttgcaatct
     7021 ggtttgtaga taaagtagca ggacgctttg gtaagaaaga agaaagttta gacaatctta
     7081 aattacctaa gttcctctca atcttccacg atacagttgt tgcatctgct accttgatgc
     7141 tcgtattctt cggggccatt cttttaatct tgggtccaga cattatgtct aataaagaag
     7201 tcatcacttc aggaactcta ttcaatcctg ctaaacaaga tttctttatg tacattatcc
     7261 aaacagcctt taccttctca gtttacttgt tcgttttgat gcaaggtgtc cgaatgttcg
     7321 tatctgagtt aacaaacgct ttccaaggta tttcaaacaa attgttgcca ggttcattcc
     7381 cagcggttga cgttgcagct tcttatggat ttggttctcc aaatgctgtc ttgtcaggat
     7441 ttacctttgg tttgattggt caattgatta caattgtctt gctcatcgtc tttaaaaatc
     7501 cgattcttat tattacagga tttgtaccag tgttctttga caatgcagcc attgcggtct
     7561 acgctgataa acgcggcgga tggaaagcgg ctgttatcct ttcctttata tcaggtgtcc
     7621 ttcaagttgc tctaggagct ctttgtgtgg cccttctcga tttggcatct tatggtggct
     7681 accatggaaa tatcgacttt gaattcccat ggcttggatt tggatatatc ttcaaatacc
     7741 ttggtattgt tggttatgta cttgtgtgtc tcttcttgct tgttattcct caacttcaat
     7801 ttgccaaagc aaaagataaa gagaaatatt acaacggtga agttcaagaa gaagcttagt
     7861 atctagaaaa ggagaaataa aatggttaaa gtattagcag cgtgcggaaa tggaatgggt
     7921 tcatcaatgg ttatcaagat gaaggttgaa aatgctctcc gtaagcttaa tcaaacagat
     7981 tttacagtca attcatgcag tgtcggtgaa gctaaaggtt tagcagtagg atatgacatc
     8041 gtaatcgctt ctcttcattt gattcaagaa ttggaagggc gaactaatgg gaagttaatt
     8101 gggcttgata acttgatgga tgataaagaa atcaccgaaa aactcagtca agcactacag
     8161 taaaaggttg gaggggggct ggacagaaac tgagagttat cgtttctgtc cttctccctc
     8221 tttaaataaa ggaggcagat atgaatttaa aacaagcttt aattgacaac gactcgatcc
     8281 gactaggttt agaggctaac gattggaaag aagcagtcaa ggtagcagta gatcccttga
     8341 ttgaaagtgg ggcaattttg ccagagtatt acgatgctat cattgaatcg actgaagagt
     8401 atgggcctta ctatatcttg atgccaggta tggctatgcc ccacgctaga cctgaagcag
     8461 gtgtgcaaag tgatgccttt tcattgatta ccttacaaaa tcctgttgta ttttcagatg
     8521 ggaaagaggt atctgttttg ttggcactag cagcaacaag ttcaaaaatt cacacaagtg
     8581 tagccattcc acaaattatt gccctatttg aattagaaga ttctattgca cgtttacagg
     8641 cttgccagac taaagaagat gtcttggcta tgattgaaga atctaaggat agcccttatc
     8701 tcgaaggatt ggatttggaa agttagaaag aggaataaag aaatgacaaa aagaatacct
     8761 aatttacaag ttgcattaga ccattcagac ttgcaaggag cgattaaagc agctgtttct
     8821 gttggtcagg aagtagatat tatcgaagct ggaactgttt gcttgcttca agttggaagt
     8881 gaactggctg aagtcttgcg tagccttttc ccagataaga ttattgtggc agacacaaaa
     8941 tgtgctgatg ctggtggaac agttgctaaa aataatgcgg ttcgtggagc agactggatg
     9001 acttgtatct gttgtgcaac catccctact atggaagcag ctctaaaggc tatcaagact
     9061 gaacgaggag aacgaggcga aatccagatc gagctttatg gcgattggac ttttgaacaa
     9121 gctcagcttt ggctagatgc aggtatctca caagctattt atcaccaatc tcgtgatgct
     9181 cttcttgctg gtgaaacttg gggtgaaaaa gaccttaata aggttaaaaa actcattgac
     9241 atgggcttcc gtgtatctgt aacaggtggt ctagatgtag atactctcaa actctttgaa
     9301 ggtgttgatg tctttacctt tatcgcaggt cgtggaatta cagaggctgc ggatccagca
     9361 ggagcagcgc gtgccttcaa ggatgaaatc agacgaattt gggggtaaat catggtacgt
     9421 ccaattggaa tttatgaaaa ggcaacccca acacacttta cttggctaga acgtttaaat
     9481 tttgccaagg agttaggctt tgattttgtc gagatgtcta ttgacgaacg tgacgagcgt
     9541 ttagcaagac ttgactggag taaggaagaa cgcttggaag ttgtcaaagc aatctatgaa
     9601 actggtgttc gtattccttc tatctgtttt tcaggccatc gtcgctaccc attgggttca
     9661 aaagatccag ttctagagga aaaatctcta gaactcatga aaaaatgtat cgaattagct
     9721 caagacttgg gagttcgtac gattcaatta gctggttacg atgtttacta tgaggaaaag
     9781 tcaccccaga cacgccaacg ttttatcaaa aatttgagaa aagcctgtga ctgggctgaa
     9841 gaagctcagg tggtacttgc tattgaaatt atggatgatc ctttcatcaa tagcatcgaa
     9901 aaatatttgg ctatagaaaa agagcttgac tctcccttcc tctttgtata tccagatatt
     9961 ggtaatgtgt ctgcatggca taatgatatc tatagtgagt tttatcttgg tcatcatgcc
    10021 atcgcagctc tccatctcaa ggatacttat gcagtgacag aaagttcaaa gggccagttc
    10081 cgagatgtac cttttgggca aggttgtgtc aaatgggaag aagctttcga tattttaaag
    10141 gaaaccaatt ataatggacc tttcctaatc gaaatgtggt ctgaaaattg tgaaacagta
    10201 gaagaaacac gcgcagccat tcaagaggcg caagctttcc tctatccact cattaagaaa
    10261 gcaggtttga tgtaagatga atcaagtaat caatgctatg cgtaaacgag tctgtgatgc
    10321 caatcaatca ttgccaaaac atggacttgt caaatttacc tggggcaatg tatcggaagt
    10381 caatcgcgaa ctcggtgtca ttgttatcaa accatcaggc gtggattatg acgaattgac
    10441 acctgaaaac atggtagtga ctgatctaga tggtaagatc ctagaagggg atttaagacc
    10501 atcttccgac ctcccaactc atgtgcaatt atataaggct tggtcagaaa ttggtagtgt
    10561 ggttcacacc cattcgacag aagctgttgg ttgggctcag gcaggtcgtg atattccttt
    10621 ctacggaaca acccatgcag attatttcta cggttcaatc ccttgcgccc gtagtttgac
    10681 caaggatgaa gtagaagtgg cctatgaaaa agatactggc ctggttatcg tagaagagtt
    10741 tgaacatcgc ggacttaacc cggttgaagt accaggaatt gttgtacgca atcacggtcc
    10801 attcacctgg ggcaaaaatc cagagaatgc tgtttatcac tctgtcgtac tagaggaagt
    10861 atcaaagatg aatcgcttta cagaacaaat caatccaaga gttgaacctg ctccccagta
    10921 catactagaa aaacactacc aacgtaaaca tggaccaaat gcttattatg gtcaaaagta
    10981 agaacgacga aggaggagaa aaagataaat ttagctcctc tttttacatt tgatttttat
    11041 tgagagtaaa gttggagttg aagtaatttt gaaagatttt ttagaaatag cgcttgatat
    11101 atatggtaaa ataaaaagaa ttgctgtgat atcaatagat ttgggggatt ttttaatatg
    11161 gtactggata aggcaagttg tgatttgctt caatatttga tggatcaaga aacgtccaaa
    11221 acgattatgg cgatttcgaa agatttgaaa gagtcaagaa ggaaaattta ttatcacatt
    11281 gacaaaatca atgctgctct gggtgacgag gcgcttcaca tcattagtat tccacgaatt
    11341 ggtattcact taacggaaga gcagagagat gcttgttgta aactattatc ggaagtagat
    11401 tcgtacgatt atatcatgag tgcgcatgaa cgtatgatga taatgttact atggataggt
    11461 atttctaaag aacgtattac gattgaaaaa ttgatagagt taacagaggt atctaggaat
    11521 actgttctca atgatttgaa tagtattcgt tatcaactaa ctttggaaca atatcaggtg
    11581 accttgcaag tgagcaagtc acagggatag caccttcatg cccaccctct taataaaatt
    11641 cagtatcttc aatcgcttct atatcatatt tttatggaag aaaatgccac ttttgtatct
    11701 attttagaag ataagatgaa agagaggtta gatgatgagt gtttgctttc tgttgaaatg
    11761 aaccaatttt ttaaggaaca ggttccttta gttgaacaag atttagggaa gaaaataaac
    11821 catcatgaaa taacttttat gttgcaggtt ctaccttatt tgctgttaag ctgtcataat
    11881 gttgaacagt atcaagaaag acatcaggat atagagaaag aattttcttt gataagaaaa
    11941 agaatagagt atcaggtgtc taagaaatta ggagaacggt tgtttcaaaa gtttgaaatt
    12001 tctttgtcag gacttgaagt ttctcttgta gctgttctcc tcctctccta tcgtaaagat
    12061 ttggatattc atgcagaaag tgatgatttt cggcaattaa aacttgcttt agaagaattt
    12121 atctggtatt ttgaatcaca aatccgaatg gagattgaga acaaggatga tttgttacga
    12181 aatttgatga tccactgtaa agccttgtta tttagaaaga cttacggtat tttttctaaa
    12241 aatcctctaa caaaacaaat tcgatccaag tatggagaat tatttttagt cactagaaaa
    12301 tctgcggaaa ttttagaagg agcatggttt attcggctaa cagacgatga tattgcctat
    12361 ttgacgattc atattggagg atttttaaaa tatacaccat cgtctcaaaa aaatatgaaa
    12421 aaagtttatc tcgtttgtga tgaaggtgtt gcggtttcga gacttttgct gaaacaatgc
    12481 aaactttatt ttccaaatga gcaaattgac actgtattta caacagaaca atttaagagt
    12541 gtggaagata ttgcacaagt tgatgtagtg attactacta atgatgattt ggatagcaga
    12601 tttccgattt taagggttaa tcctatcctt gaagcagaag atattttgaa aatgctagac
    12661 tatcttaaac acaatatatt tcgtaataag agcaaaagtt tcagtgaaaa tctttctagt
    12721 cttatttcgt cttatattgt agacagcaag ttggctagta agttccaaga agaggttcaa
    12781 acacttataa atcaagaaat agtagttcaa gcttttttgg aagatatttg aaggacagtc
    12841 caatgatgaa cacaaacctg tgtttttctt ggtctttttt agtgttttga agggtggtat
    12901 actaatctca aagataacaa ttatatccaa aggaggcaac atatgccaaa cgtcaaagaa
    12961 attacaagag agtcatggat tttagccact ttcccagagt ggggaacatg gttgaacgaa
    13021 gaaatcgaag aagaagtcgt acctgaaggc aactttgcca tgtggtggct aggcaactgt
    13081 ggtacttgga ttaagacacc agctggtgct aacgttgtca tggacctttg gtcaaaccgt
    13141 ggaaaatcaa ccaaaaaagt gaaagatatg gttcgtgggc accaaatggc aaatatggca
    13201 ggtgttcgta agttgcaacc aaacttgcgt gttcagccaa tggttatcga tccatttgct
    13261 atcaacgaac tagactatta cttagtttca cacttccaca gtgatcatat cgacccatac
    13321 acagctgcag caattctcaa caatcctaag ttagagcatg ttaagtttat cggtccttac
    13381 cactgtggac gaatctggga aggatggggg gttccaaaag aacgtatcat cgttgttaaa
    13441 ccaggtgaca ctatcgaatt aaaagatatg aagattcatg cagtagaatc atttgaccgt
    13501 acttgcttgg taactctccc agtgaacggt gctgatgaga caggcggtga acttgctggc
    13561 ttggctgtta cagatgaaga aatggctcaa aaggctgtta actatatctt tgaaacacca
    13621 ggtggaacca tctatcatgg tgcagattct cacttctcaa actattttgc aaaacatggt
    13681 aaagacttta aaattgatgt tgctttgaat aactatggtg aaaatccggt aggtatccaa
    13741 gacaaaatga catctatcga ccttcttcgt atggcagaaa atctgcgtac caaagtcatt
    13801 atcccagttc actatgatat ctggtctaac ttcatggctt ctactaatga gattctagaa
    13861 ctttggaaaa tgcgaaaaga tcgcttgcaa tacgatttcc atccatttat ctgggaagtt
    13921 ggcggtaagt acacttatcc tcaagatcaa cacttagtag aataccatca tccacgtggt
    13981 tttgatgatt gttttgaaca agactctaac attcaattta aagctttgct ataatataaa
    14041 aatattcttt ggaggttatc cgtatgttgc atgatacgga taattttcat ataatagtaa
    14101 aatagaatgt gtgattcaat aatcacctca aatagaaagg aaattctatg tcaaatctat
    14161 ctgttaatgc aattcgtttt ctaggtattg acgccattaa taaagccaac tcaggtcatc
    14221 caggtgtggt tatgggagcg gctccgatgg cttacagcct ctttacaaaa caacttcata
    14281 tcaatccagc tcaaccaaac tggattaacc gcgaccgctt tattctttca gcaggtcatg
    14341 gttcaatgct cctttatgct cttcttcacc tttctggttt tgaagatgtc agcatggatg
    14401 agattaagag tttccgtcaa tggggttcaa aaacaccagg tcacccagaa tttggtcata
    14461 cggcagggat tgatgctacg acaggtcctc tagggcaagg gatttcaact gctactggtt
    14521 ttgcccaagc agaacgtttc ttggcagcca aatataaccg tgaaggctac aatatctttg
    14581 accactatac ttacgttatc tgtggagacg gagacttgat ggaaggtgtc tcaagcgagg
    14641 cagcttcata cgcaggtttg caaaaacttg ataagttggt tgttctttat gattcaaatg
    14701 atatcaactt ggatggtgag acaaaggatt cctttacaga aagtgttcgt gaccgttaca
    14761 atgcctacgg ttggcatact gccttggttg aaaatggaac agacttggaa gccatccatg
    14821 ctgctatcga aacagcaaaa gcttcaggca agccatcttt gattgaagtg aagacggtta
    14881 ttggatacgg ttctccaaac aaacaaggaa ctaatgctgt acacggcgcc cctcttggag
    14941 cagatgaaac tgcatcaact cgccaagccc tcggttggga ctacgaacca tttgaaattc
    15001 cagaacaagt atatgctgat ttcaaagaac atgttgcaga ccgtggcgca tcagcttatc
    15061 aagcttggac taaattagtt gcagattata aagaagctca tccagaactg gctgcagaag
    15121 tagaagccat catcgacgga cgtgatccag tcgaagtgac tccagcagac ttcccagctt
    15181 tagaaaatgg tttttctcaa gcaactcgta attcaagtca agatgccttg aatgttgtgg
    15241 cagctaaatt accaaccttc ctaggtggat cagctgacct tgctcactca aacatgactt
    15301 atatcaagac ggatggactt caagacgata ccaatcgctt gaatcgtaac attcagtttg
    15361 gtgttcgtga atttgcaatg ggaacaatct tgaacgggat ggcccttcat ggtggacttc
    15421 gtgtatacgg tggaactttc ttcgtcttct ctgactatgt gaaggcagct gtccgcttgt
    15481 cagccttaca aggacttcct gtgacttatg tctttaccca tgattcaatc gcagttgggg
    15541 aagatggtcc gactcacgaa ccagttgagc atttagcagg tcttcgtgct atgccaaatc
    15601 taaatgtttt ccgtccagca gatgcgcgtg aaacgcaagc agcttggtac cttgcagtga
    15661 caagtgagaa aacaccaact gcccttgtct tgacacgtca aaacttgact gttgaagatg
    15721 gaacagactt cgacaaggtt gctaaaggtg cttatgttgt atatgaaaat gcagccgact
    15781 ttgataccat cttgattgcg acaggttcag aggtcaatct agctgtcgca gctgccaaag
    15841 aattagctag taaaggcgaa aaagtccgcg tagttagcat gccatctaca gatgtctttg
    15901 ataaacaaga tgcagcttac aaggaagaga ttcttccaaa tgcagtccgc cgtcgtgttg
    15961 cagtcgaaat gggtgcaagt caaaactggt acaaatatgt tggtctcgat ggtgccgttc
    16021 taggtattga taccttcgga gcctctgccc cagcaccaaa agtattggca gaatatggct
    16081 ttactgtaga aaatcttgta aaagttgttc gaaacttgaa acaatcctaa aaatcagggc
    16141 gtaagctctg gtttttctta ccagaaaagt aaggtacaat cttgtaaaag tagctgaaat
    16201 ttgatatagt agtcctatgt aaaagacaaa ggagaaaaca atgaatccaa atattacttt
    16261 tttaatcatg cttgtaggta tgatggcctt gatgttcttt atgcaacgct ctcaaaagaa
    16321 acaagcacaa aaacgtatgg aaagcttaaa taaactacaa aaaggctatg aagtgattac
    16381 aatcggtgga ctttatggaa cagtcgatga agtagatacg gagaagggaa caatagttct
    16441 tgacgtagat ggagtttact tgacttttga actagctgct atcaagacag tattaccgct
    16501 gaaagaaaca gcttcactag aaggcgcaat tgaaaaataa gaagggatca cgaactcccg
    16561 tttttctata aaagaaagga aatgggatga aaaaattagt ctttgtctgt ctgggaaata
    16621 tttgccgtag ccctatggcc gagtttgtta tgaaatcaat gacagataac tacgaaatcc
    16681 aaagtcgagc aacttcctct tgggaacatg gcaatccgat tcataagggg actcagggaa
    16741 tttttcaaga gtatgagatt ccttatgaca agaacaagac atcgcttcag attagtaagg
    16801 aagattttga agcctttgat tatattatcg gaatggacgc ttcaaatgtt tccgacttac
    16861 gtcagatgtg tccagtagac tgtcaagata agatttactc attttcatct gaaagtgttc
    16921 cagacccttg gtatacagga gattttgaag aaacctatcg acgtgttcaa gagggctgtc
    16981 aagcttggtt agaacgttta gaaaaggaga gttaaggtgg aaaatcttac gaatttttac
    17041 gaaaagtatc gtgtctatct gactcgtcca cgtttagagc ttttggcagt agttaccatt
    17101 gttttctgtg ctgtactcgt cttttttcta aatattccag gaaaaggtgt cttaaaactc
    17161 gataatggaa cgattgttta tgatggcagt cttgtccgtg gtaaaatgaa tggccaaggt
    17221 accattacct tccaaaatgg agaccaatat acaggtggct tcaacaatgg agccttcaac
    17281 ggaaaaggta cctttcaatc taaagaaggc tggacctacg aaggtgattt tgtaaatggt
    17341 caggctgaag gaaaagggaa actaacaaca gaacaagaag tcgtttatga aggaactttt
    17401 aaacaaggcg tttttcaaca aaaataaagc ctccttatca aaggaggtat tattagaatt
    17461 acaaggtaag cgcttacctg taaatccctt tctttccaaa tccctcttcc aagcaagttt
    17521 gtgaaataaa aaatatttga aataaatttc acaaacttca aagataaaac ctgataagaa
    17581 aagaaaatga gaaaagtttc acaagagttt aaaaattctt tgtgaaatgt ttatgaaact
    17641 gtttacaaag ttgaaataat gcgttataat aaacttgtga aaaaattaac aaaggatatc
    17701 gttccttgaa agctatggag gaaaatatgg ctgataaaaa aactgtgaca ccagaggaaa
    17761 agaaactcgt tgctgaaaaa cacgtagatg agttggttca aaaagctcta gttgcccttg
    17821 aagaaatgcg taaattggat caagagcaag ttgactacat cgttgccaaa gcatcagtag
    17881 cagctttgga tgcccacgga gaattggctt tacatgcctt tgaagaaaca ggacgtggtg
    17941 tatttgaaga taaagcaact aagaacttgt ttgcctgtga acacgtagta aacaacatgc
    18001 gccacactaa gacagttggc gttatcgaag aagacgatgt aacaggattg actcttattg
    18061 ctgaaccagt tggtgttgtt tgtggtatta ctccaacaac aaacccaaca tcaacagcaa
    18121 tcttcaaatc attgatttca ttgaagacac gtaacccaat cgtctttgcc ttccatccat
    18181 cagcacaaga atcatctgct catgcagctc gtatcgtccg cgatgcagct atcgcagctg
    18241 gtgctcctga aaactgtgtg caatggatta ctcaaccatc tatggaagca acaagtgccc
    18301 ttatgaacca cgaaggtgtt gcgacaatcc ttgcaacagg tggtaatgcc atggttaagg
    18361 cagcttattc atgtggtaaa ccagctcttg gggtaggtgc cggaaacgtt ccagcttatg
    18421 ttgaaaaatc agcaaacatt cgtcaagcag cacacgatat cgtcatgtct aaatcatttg
    18481 ataacggtat ggtctgtgca tctgaacaag cagttatcat tgataaagaa atttacgatg
    18541 aatttgtagc agagttcaaa tcttaccaca cttactttgt aaacaaaaaa gaaaaggctc
    18601 ttcttgaaga gttctgcttc ggcgtcaaag caaacagcaa aaactgtgct ggtgcaaaat
    18661 tgaacgctga catcgttggt aaaccagcaa cttggattgc agaacaagca ggatttacag
    18721 ttccagaagg aacaaacatt cttgctgcag aatgtaaaga agttggcgaa aatgagccat
    18781 tgactcgtga aaaattgtca ccagttattg cagttttgaa atctgaaagc cgtgaagatg
    18841 gtattactaa ggctcgtcaa atggttgaat ttaacggtct tggacactca gcagctatcc
    18901 acacagctga cgaagaattg actaaagaat ttggtaaagc tgttaaagct attcgtgtta
    18961 tctgtaactc accttctact tttggtggta tcggggacgt ttacaatgcc ttcttgccat
    19021 cattgacact tggatgtggt tcttacggac gcaactcagt tggggataac gttagtgcca
    19081 ttaacctctt gaatatcaaa aaagtcggaa gacggagaaa taacatgcaa tggatgaaac
    19141 ttccttcaaa aacatacttt gaacgtgatt caattcaata ccttcaaaaa tgtcgtgacg
    19201 ttgaacgtgt catgatcgtt actgaccatg ccatggtaga gcttggtttc cttgatcgta
    19261 tcatcgaaca actggacctt cgtcgcaata aggttgttta ccaaatcttt gcggatgtag
    19321 aaccggatcc agatatcaca actgtaaacc gtggtactga gattatgcgt gccttcaaac
    19381 cagataccat catcgcactc ggtggtgggt ctccaatgga tgctgccaaa gtaatgtggc
    19441 tcttctacga gcaaccagaa gtggacttcc gtgaccttgt ccaaaaattc atggatatcc
    19501 gtaaacgtgc cttcaagttc ccattgcttg gtaagaagac taaattcatc gcgattccaa
    19561 ctacatctgg tacaggatct gaagtaacac catttgccgt tatctctgat aaagcaaaca
    19621 accgtaaata cccaatcgct gactactcat tgacaccaac tgtggcaatc gtagatcctg
    19681 ctttggtatt gacagttcca ggatttgttg ctgctgatac tggtatggac gtattgactc
    19741 acgcgacaga agcatacgta tcacaaatgg ctagtgacta cactgatggt ttagcacttc
    19801 aagccattaa attggtcttt gaaaatctcg aaagctcagt taagaatgct gacttccact
    19861 cacgtgagaa aatgcataac gcttcaacaa tcgctggtat ggcctttgcc aatgccttcc
    19921 taggtatttc tcactcaatg gcccataaga ttggtgcgca attccacaca atccacggtc
    19981 gtacaaatgc tatcttgctt ccatacgtta tccgttacaa cggtacacgt ccagctaaga
    20041 cagcaacatg gcctaagtac aactactacc gtgcagatga aaaataccaa gatatcgcac
    20101 gcatgcttgg acttccagct tctactccag aagaaggggt tgaatcttac gcaaaagctg
    20161 tctacgaact cggtgaacgt attgggatcc aaatgaattt tagagaccaa ggaattgacg
    20221 aaaaagaatg gaaagaacat tctcgtgaat tagccttcct ggcttatgaa gaccaatgtt
    20281 caccagctaa cccacgtctt ccaatggtag atcatatgca agaaatcatc gaagatgcat
    20341 actatggcta caaagaaaga ccaggacgcc gtaaataatt gtttatcagt ctagaagcaa
    20401 gacaaaaact caatttgagg gaaagatcca gtaatttttc tatgataaaa ggcatcctat
    20461 caaggttttt gaacacctga taggatgcct ttttatgata ttgaggcctt tttgcccttt
    20521 ttgaaaaact agaatagaaa caaaatatat aatagattga aactagaata gtacacatct
//
LOCUS       DAVHSI010000035        19732 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.035, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000035 DAVHSI010000000
VERSION     DAVHSI010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.035"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            2..74
                     /locus_tag="VVR21_001547"
     tRNA            2..74
                     /locus_tag="VVR21_001547"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VVR21_001548"
     tRNA            99..171
                     /locus_tag="VVR21_001548"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VVR21_001549"
     tRNA            177..258
                     /locus_tag="VVR21_001549"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VVR21_001550"
     tRNA            277..349
                     /locus_tag="VVR21_001550"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VVR21_001551"
     tRNA            372..443
                     /locus_tag="VVR21_001551"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VVR21_001552"
     tRNA            451..536
                     /locus_tag="VVR21_001552"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VVR21_001553"
     tRNA            546..619
                     /locus_tag="VVR21_001553"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VVR21_001554"
     tRNA            635..708
                     /locus_tag="VVR21_001554"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VVR21_001555"
     tRNA            714..787
                     /locus_tag="VVR21_001555"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VVR21_001556"
     tRNA            801..874
                     /locus_tag="VVR21_001556"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VVR21_001557"
     tRNA            885..974
                     /locus_tag="VVR21_001557"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            988..1061
                     /locus_tag="VVR21_001558"
     tRNA            988..1061
                     /locus_tag="VVR21_001558"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1022..1024,aa:Met,seq:cat)
     gene            1065..1137
                     /locus_tag="VVR21_001559"
     tRNA            1065..1137
                     /locus_tag="VVR21_001559"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1098..1100,aa:Phe,seq:gaa)
     gene            1157..1227
                     /locus_tag="VVR21_001560"
     tRNA            1157..1227
                     /locus_tag="VVR21_001560"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1189..1191,aa:Gly,seq:tcc)
     gene            1263..1336
                     /locus_tag="VVR21_001561"
     tRNA            1263..1336
                     /locus_tag="VVR21_001561"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Ile,seq:gat)
     gene            1343..1430
                     /locus_tag="VVR21_001562"
     tRNA            1343..1430
                     /locus_tag="VVR21_001562"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1377..1379,aa:Ser,seq:gct)
     gene            complement(1564..2001)
                     /locus_tag="VVR21_001563"
     CDS             complement(1564..2001)
                     /locus_tag="VVR21_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6055392.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(2252..3187)
                     /locus_tag="VVR21_001564"
     CDS             complement(2252..3187)
                     /locus_tag="VVR21_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU6055393.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(3184..4044)
                     /locus_tag="VVR21_001565"
     CDS             complement(3184..4044)
                     /locus_tag="VVR21_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU6055394.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIKSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            4152..6314
                     /locus_tag="VVR21_001566"
     CDS             4152..6314
                     /locus_tag="VVR21_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU6055395.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     ELQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            6349..7608
                     /locus_tag="VVR21_001567"
     CDS             6349..7608
                     /locus_tag="VVR21_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU6055396.1"
                     /translation="MEWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGSFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            7622..8488
                     /locus_tag="VVR21_001568"
     CDS             7622..8488
                     /locus_tag="VVR21_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6055397.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            8502..9335
                     /locus_tag="VVR21_001569"
     CDS             8502..9335
                     /locus_tag="VVR21_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6055398.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            9336..9416
                     /locus_tag="VVR21_001570"
                     /pseudo
     CDS             9336..9416
                     /locus_tag="VVR21_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9554..10996
                     /gene="gtfA"
                     /locus_tag="VVR21_001571"
     CDS             9554..10996
                     /gene="gtfA"
                     /locus_tag="VVR21_001571"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU6055399.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            11134..12327
                     /locus_tag="VVR21_001572"
     CDS             11134..12327
                     /locus_tag="VVR21_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU6055400.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            13013..14992
                     /locus_tag="VVR21_001573"
                     /pseudo
     CDS             13013..14992
                     /locus_tag="VVR21_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
     gene            15059..16555
                     /locus_tag="VVR21_001574"
     CDS             15059..16555
                     /locus_tag="VVR21_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055401.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            16555..17481
                     /locus_tag="VVR21_001575"
     CDS             16555..17481
                     /locus_tag="VVR21_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055402.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            17490..18557
                     /locus_tag="VVR21_001576"
     CDS             17490..18557
                     /locus_tag="VVR21_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055403.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18568..19494
                     /locus_tag="VVR21_001577"
     CDS             18568..19494
                     /locus_tag="VVR21_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055404.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5684 a         3576 c         4240 g         6232 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag gtaacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt aagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttattaacgc gggatggagc agctcggtag ctcgtcgggc
     1021 tcataacccg aaggtcgtag gttcaaatcc tgctcccgca ataaggctcg gtagctcagt
     1081 tggtagagca atggattgaa gctccatgtg tcggcggttc gattccgtct cgcgccattt
     1141 tattgatagt atttatgcgg gtgtagttta gtggtaaaac tacagccttc caagctgttg
     1201 tcgcgagttc gattctcgtc acccgctttg aactttgttc aaattaccaa gttttttaac
     1261 ttgggcgcgt agctcaggtg gttagagcgc acgcctgata agcgtgaggt cggtggttcg
     1321 agtccactcg tgcccattaa ttggagaatt actcaagagg ctgaagagga cggtttgcta
     1381 aatcgttagg tcgggtaact ggcgcaaggg ttcgaatccc ttattctccg ttttaatgag
     1441 agtttgtaac tctctttttt atttttagag acaataaagc ttcagatccg taaaacttaa
     1501 ttgaattact aatctgaagt tatttttatg gctctttgtc aactgtagtg ggttgaagaa
     1561 aagctaagct cgagaaagga caaatttcgt cctttctttt ttgatgttca aagcgataaa
     1621 aatccgtttt ttaaagtttt caaagtttcg aaaaccaaag gcattgcact tgataagttt
     1681 gatgagatta ttggtcgctt ccagtttggc gttagaatag tgtagttgaa gggcgttgac
     1741 aatcttttct ttatctttga ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg
     1801 cttaagattg tcctcaataa gtccgaaaaa tttctctggt tcctttttct tcattagact
     1861 tccacaatca gggcaagatg gagcctcata atccagctta gcgataattt ctttgtgggt
     1921 atccatattg atgatatcta gaatcttgat gtttgggtct ttaatgtcta gtaattttgt
     1981 gataaaatgt aattgttcca tatgattctt tctaatgagt tgttttgtcg cttttcatta
     2041 taggtcatat gggacttttt ttctacacaa aataggctcc ataatatcca tagggaattt
     2101 acccactaca aatattatag agcccgtttt aatgagagtt tgtaactctc ttttttgttt
     2161 ttagagacaa taaaacttca gatccgtaaa acttaattga attactaatc tgaagttatt
     2221 tttatatcgt ttatattata attgtgttat tttacttcca actattgaga gaaatttcgc
     2281 cactatttag ccagatttct tttccgttat cacattgaac taaaagtttt ccattttctg
     2341 agatgtcttt agcaagtccc ttgtagtctt tttgctctag tgtgaaagtg acttcttttc
     2401 ctagaatgaa tgactgtttt ttgtataggt ataatagctc ttctgctggt gtttcgaaga
     2461 aagcacgcca gatttctatg atcaattcat tccttgttat aggagctgta gctttaaata
     2521 agctggcagc tttttctttt aattcctgag ggaagtcttt aatagtgaaa ttgataccta
     2581 ctccaataat gatatctgtg actaagccag tttctacaga ggtcattgct tcagtaagga
     2641 ttcctccaat tttatgattg tttagataga tatcattgac ccattttatg tcgacatcta
     2701 ttaaagttag gttcttaatg gctttgtaga cagctccagc tacaagtagt gtgtaggatg
     2761 gtaatttgtc ataggggaga tttggtttaa gatggagtgt catataaata ccaccttgtg
     2821 gtgagtagaa ggaacgttga aaacggcctc ggcctgctgt ttgataggaa gctagataga
     2881 gggtatttgc ttcatggcct aaatcaattg cttcttttgc atctagttgt gttgattttg
     2941 tttcgggttt aaagctgact ttaattggaa gattttcttc tagaatctct ggaagaataa
     3001 ggtcaccatt catcagttta tatcctctat ttttgatact atcaatttca atgccttctt
     3061 gttctagtcg cttgatggct ttccaaattg ctgttcggct tagggatagt ttttctgcga
     3121 ttttttctcc gctgatatag tcggtttctt tagataggat ttggtagaca gcttggtagg
     3181 atttcataat gttgcctttc ttactagttg gtattgagag tattcttttc ttgtatgact
     3241 tggagtctga ttaaagtatt gtttataagc tttcgaaaaa tggagtggat ctgaaaaacc
     3301 taccgagtat gcaattacct tgatggactc ttgggtattt tcgagaagtt gtctagctcg
     3361 gtgcattcga acgtagagta ggtattcttt gggtgataag gtattaaatt ctttgaatac
     3421 gcttgataag tagcttctgt gaacggatag ttcttttgct aaatcttgaa ttgtaagtga
     3481 ttgaggatag tggctatcaa ttaatcgttt gcattcaaga tagagttggt gggttgatga
     3541 aatattcttt tttttctgat tgggagcaat agttcccaga tgaaacatca gttcatgaag
     3601 ttgtcccatg atatggagtt gagctaattc acttgatttt gtaatctgag cgaagcggac
     3661 aatgtctgag atgagttttg cagtagtctg ggtatgacaa gtttcagatt tgatgagata
     3721 ggattgatca gaaatttggg aaagagcaaa ataatcaggg gctttccctc cagtgattcc
     3781 taaccagtag taggcccaag gttctttact atctgcttga taaaaggtta gttcctctgg
     3841 ttttaataga aagaaatctc cttcttttaa atcaacaatt ttacccttgt aatgaaattt
     3901 tccttgtcct ttagtaatgt aatgtaggac gtatgtatca cgaatggctg gaccaaaaga
     3961 gtaattaggt gtgcattcct catatccata aaagcttagg gcaaggtcga ttgttccagt
     4021 ctggtattct gaaaaaacta acatgtgcta cctcctacct aacattttac catattcttg
     4081 agacattttt ctattttgga aagcgatttc aggtgataaa atagagtcaa taaagtgatg
     4141 aggtgaagta aatgggagtt aggatagaga ataatctatt ttatgttgag agtaaaaatc
     4201 taagtttgat tattgaaaat cgaaatggct acttactttt gaaacattta ggaaagacta
     4261 ttaagaacta taaaggttcc aatagtgttt atgaacgaga ccatgccttt tcaggaaatc
     4321 caacagctac taatcgaacc tttagtttag atactcaacg tcaaattttt ggacaacatg
     4381 gcttaggaga ttttaggaaa ccaaccatac aggttcagca taatgtaact gaagtaacag
     4441 actttcgatt tgtagaagca aagattttaa aaggtcagaa tggtccacag ggcttacctt
     4501 ctccacatag catggacgat acagagactc ttgtcttaat gttagaagat tctaaggctc
     4561 aacttagtct gactttgtat tatactactt ttaataatga tgcgactatt gctagctaca
     4621 gtaaattaga taataatagt aatcaggaag ttgtcatcca taaagatttt tcttttatgg
     4681 ctgattttcc agctgcagat tacgaaatag taactctgca gggtgcttat gctcgtgaaa
     4741 agactgttag acgtcaacag gtagaacaag gaatcttttc gattagttca aaccgaggtg
     4801 cttctggtca tgctcaaaca ccagctcttc tactatgcga acaaggagtc acagaggatg
     4861 ctgggaatgt gtttgctatt caactaatgt atagtggcaa ctttgaagct tttgttcaaa
     4921 aaaatcaatt gaatgaagtt cgggtggcta ttggcattaa tccagaaaac ttttcttgga
     4981 agttagcccc tgaggaatac tttgaaacac cggtagcttt agtgactcat tcagatcagg
     5041 gattaactgg tattagtcat gaaagtcaga attttgtact gaagcacatt atgctaagtg
     5101 aattttctaa aaaagaacgt ccaattctaa tcaataactg ggaagctact tactttgact
     5161 ttcagagaga aaaactgtta gagttagcag atgaagctaa gaaagttggc attgaacttt
     5221 ttgtattaga tgatggttgg tttggcaatc gttttgatga taatcgtgct ttaggtgatt
     5281 gggttgttaa tgaggaaaaa ctgggtggaa gtctagaaag tctgatttca gctatccatg
     5341 aaagaggttt gcagtttgga ctttggttag aacccgaaat gatttctgta gatagtgatt
     5401 tgtatcgtca acatcctgac tgggctattc aggttcctgg ctatgagcat acttattctc
     5461 ggaatcaatt agtacttaat cttgccaatc ctcaggtagt agaatacttg aaaagtgtct
     5521 tagatcaact cctatcttat catgatattg attacattaa atgggatatg aaccgcaata
     5581 tcactaagct agggaatgga ttaacttatc tagagacaca gatgcaatct catcagtaca
     5641 tgctggggct ttacgaactc gtttcttatc tgacagagaa gcacagccat attctctttg
     5701 agtcctgctc tggtggtggt ggacgaaatg atcttggtat gatgcgctat ttcccacaag
     5761 tctgggctag tgataatact gatgccattg cacgtttacc aattcaatac ggttcatcct
     5821 atctctatcc aaccatttct atgggggctc atgtgtcagc agtaccgaat catcagatgg
     5881 gacgaatgac accattagaa acacgtggcc atgtagcaat gatgggaaat ttgggctatg
     5941 agcttgattt gacaaattta tcagatgaag agaaagctac gattgctaat caggtgaact
     6001 tgtataaaga attacgacca gtagttcagt taggacagca gtatagacta attaatcctg
     6061 atactgcatc caatgaagca gctgtacaat ttaattacgg aaatcaaacg attgtaacct
     6121 acgttcgcgt tttatctgtt gtagagacca tggaaacaac tttaaaatta aaagatttgg
     6181 atgaagaggg actatatgaa ttacaggaaa atggcgaagt ttactcaggt gcagaactaa
     6241 tgtatgcggg cctaactgtt atcttatccc aaggagattt tttgagtaga cagtatattt
     6301 ttagaagact atgataaggg tgtataaatt tataaaggag gctttctaat ggaatggtat
     6361 aaaaaaatcg gacttcttgc aactacaggt ttagctttgg ttgggctcgg cgcttgctcc
     6421 aactatggta aatctgcgga tggcacagtg accatcgagt atttcaacca gaaaaaagaa
     6481 atgaccaaaa ccttggaaga aatcactcgt gattttgaga aggaaaaccc taagatcaag
     6541 gtcaaagtcg tcaatgtacc aaatgctggt gaagtattga agacacgcgt tctcgcagga
     6601 gatgtgcctg atgtggtcaa tatttaccca cagtccatcg aactgcaaga atgggcaaaa
     6661 gcaggtgtct ttgaagattt gagcaacaaa gactacctga aacgcgtgaa aaatggctac
     6721 gctgaaaaat atgctgtaaa cgaaaaagtt tacaacgttc cttttacagc taatgcttat
     6781 ggaatttact acaacaaaga taaattcgaa gaactgggct tgaaggttcc tgaaacctgg
     6841 gatgaatttg aacagttagt caaagatatc gttgctaaag gacaaacacc atttggaatt
     6901 gcaggtgcag atgcttggac actcaatggt tacaatcaat tagcctttgc gacagcaaca
     6961 ggtggaggaa aagaagcaaa tcaatacctt cgttattctc aaccaaatgc cattaaattg
     7021 tcggatccga ttatgaaaga tgatatcaag gtcatggaca tccttcgcat caatggctct
     7081 aagcaaaaga actgggaagg tgctggctat accgatgtta tcggatcctt cgcacgtggg
     7141 gatgtcctca tgacaccaaa tgggtcttgg gcgatcacag cgattaatga acaaaaaccg
     7201 aactttaaga ttgggacctt catgattcca ggaaaagaaa aaggacaaag cttaaccgtt
     7261 ggtgcgggag acttggcatg gtctatctca gccaccacca aacatccaaa agaagccaat
     7321 gcctttgtgg aatatatgac ccgtccagaa gtcatgcaaa aatactacga tgtggacgga
     7381 tctccaacag cgatcgaagg ggtcaaacaa gcaggagaag attcaccgct tgctggtatg
     7441 accgaatatg cctttacgga tcgtcacttg gtctggttgc aacaatactg gaccagtgaa
     7501 gcagacttcc ataccttgac catgaactat gtcttgaccg gtgataaaca aggcatggtc
     7561 aatgatttga atgccttctt taacccgatg aaagcggatg tggattagga gtagagagac
     7621 tatgaaaaaa gtattacaaa aatattgggc atgggctttt gtggtcatcc ccctcttgtt
     7681 acaagcaatt ttcttctatg tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg
     7741 gacaggattg acttacaact acaaatttgt cggcttaaac aactttaagc tcctcttcat
     7801 ggatccaaaa ttcatgaatg cgattggctt taccgcaatc attacgattg ccatggtggt
     7861 tggtgagatt gcactcggga tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca
     7921 aaccttcttc cgtgcttggt tcttcttccc agctgtttta tctggtttga cagtggcttt
     7981 gatcttcaag caagtcttca actacggtct tccagcgatt gggaatgccc ttcatattga
     8041 atttctccaa accagtcttt tagggactaa gtggggagca atctttgcgg ctgtctttgt
     8101 ccttctttgg caaggggtgg ctatgcccat catcatcttc ctagctggtt tgcaatctat
     8161 tccaactgag attacagagg cagcaaggat tgatggtgcg actagcaagc aagttttctg
     8221 gaacattgaa ttgccttact tgctaccaag tgtctctata gtctttatcc tagccctaaa
     8281 aggtgggctg actgcctttg accaagtctt tgccatgacc ggtggtggtc caaacaatgc
     8341 cacaacctca cttgggctct tggtttataa ctatgccttt aaaaacaacc aattcggtta
     8401 tgccaatgcc attgccgtaa tcttgttctt cttaattgta gtgatttcga tcatccaatt
     8461 gagagtatct aagaaatttg aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa
     8521 aagccctgat tggcaaatac attctattga ttctaggatc ggttctgatt ttagtgccgc
     8581 tccttgctac cctctttagt tccttcaaat ccactaagga tattgtagat aatttctttg
     8641 gctttccaac caacttcaca tgggacaact ttagccgtct cttagctgat gggattggag
     8701 gctattattg gaactctgtc gtcatcactg tcttgtcttt acttgcagta atgatcttta
     8761 tccctatggc agcctactcc atcgctcgca atatgagtaa aagaaaagcc tttaccatca
     8821 tgtataccct cttaatcctc ggaatcttcg tacctttcca agtcatcatg attccgatta
     8881 cggttatgat gagtaaactc ggtttggcta atacctttgg tttgatcttg ctctacttga
     8941 cctatgcgat tccacagacc ctctttctct atgttggcta tatcaaaatc tcgattccag
     9001 aaagtctgga tgaagcagca gagatcgatg gggctaatca atttacaacc tatttccgca
     9061 tcatcttccc aatgatgaaa ccgatgcatg cgacaaccat gatcatcaat gccctttggt
     9121 tctggaatga cttcatgttg ccactccttg tcttgaaccg ggattccaaa atgtggactc
     9181 tgcctttgtt ccaatacaac tacgcaggcc aatatttcaa cgactacgga ccaagctttg
     9241 cctcttacgt ggtcggcatt atcagtatca ccattgtcta tctcttcttc caacgccata
     9301 tcatcgcagg aataagcaac ggggcagtga agtaatactc aatgaaaatc aaagagcaaa
     9361 ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtggat gaaactgacg
     9421 aagtcagtaa ccatacctac ggtaaggcga cactgacgtg gtttgaagag attttcgaag
     9481 agtataacat gaatttgatt tacgaagcca gatcatatga gacttggctt caattagaaa
     9541 aaggagagta atgatgccaa ttcaaaataa aaccatgttg attacctatt ctgatagcct
     9601 tggaaataat cttaaagact tatatgataa tttggaagag cattttggag atgctattgg
     9661 aggagttcac cttttaccat ttttcccatc aacaggtgat cgtggatttg cgccagttga
     9721 ctacgacgaa gtggactcag cttttggtga ttgggaggat gttaagcgtt taggtgagaa
     9781 atattatctt atgtttgatt ttatgattaa tcatatttct cgtcaatcca agtattataa
     9841 ggactatcaa gaaaaacatg aagccagtga atttaaagat ctctttttaa actgggataa
     9901 gttttggcca gaaaaccgtc cgacacagtc tgatgtagat ttaatttaca agcgtaagga
     9961 tcgtgcacca aagcaagaga ttgtgtttga agatggttca gtggaacatt tgtggaatac
    10021 ctttggtgag gagcagattg atcttgatgt gaccaaagaa gtaactatgg aatttatccg
    10081 taagaccatt cagcacttgg caagtaatgg gtgtgatttg attcgtctag atgcctttgc
    10141 ttatgcagtg aagaaattgg atactaatga tttctttgtg gaaccagata tttgggattt
    10201 attggacaaa gttcgagata tcgctgctga gtatgggaca gagattttac ctgagattca
    10261 tgaacactat tcgattcagt ttaaaatagc agaccatgat tactatgttt atgattttac
    10321 tcttccaatg gtgacacttt atactcttta cagttccaga acagagcgtt tggctaagtg
    10381 gttgaagatg agcccgatga agcaatttac gacgctagat acccatgatg ggattggagt
    10441 agtagatgtc aaggatatcc tgaccgatga ggagattgac tatgcttcaa atgaactcta
    10501 taaggttgga gccaatgtca aacgtaagta ctctagtgcc gagtataaca acttagatat
    10561 ctaccaaatc aattcaacct actattcagc gcttggagat gatgatgtca agtattttct
    10621 cgctcgtcta attcaagctt ttgccccagg tattcctcag gtttactatg tgggtctatt
    10681 agcaggcaag aatgacttga aattattaga agaaactaaa gaaggtcgaa atattaatcg
    10741 tcattactat agcaacgagg aaatagcaaa agaagtgcaa cgacctgttg tgaaggccct
    10801 tctcaatcta ttttctttcc gtaaccgttc agaagccttt gatctagaag ggactactga
    10861 gatagagaca ccaacagctc acagcattgt aatcaaacgt caaaataaag ataagtccgt
    10921 aacagcagta gcagaaattg atttgcaaaa tcagacttat cgggtaattg agaatggagt
    10981 tgaagtatca ttttgaagcc ttgatatggt ggataaaata gggtttttat tttggaaaac
    11041 gtttcctttg ttttcaaatt gctaaaaaag tggtacaata taggatagct tactattatc
    11101 tgaatcagct gatttggaga gaaaggattc attttgaaat caataggctt tattgaaaag
    11161 ctgaaggggt tgtctagtaa agagctgatt ttattgggaa ttatcctaag tatcttttta
    11221 cccttttatc tttttgtagt tgtactctgt ttatatatta tcagtttgat ttttacagga
    11281 gacatgaaaa gtattcttca gaaaatgggg gagcatccga tgctgcttct ttttcttagc
    11341 tatagtactg ttatatccat tcttgcacaa aattggatgg gtcttgtggc ttcagtagga
    11401 atgtttctat ttactatttt ctttttgcac tatcagtcga ttttatccca taaattcttt
    11461 cgattgattt tgcagttcgt cttgtttggt agtgtcttgt cagctgcttt tgccagttta
    11521 gaacatttcc aaattgtgaa gaaatttaac tatgcttttc tttcacccaa tatgcaggtg
    11581 tggcatcaga accgggcaga agtgaccttc tttaatccta attattatgg aattatttgt
    11641 tgtttctgta ttatgattgc tttctatctg tttacaacga ccaagttgaa ttggttgaaa
    11701 gtattctgtg tgattgcagg ctttgttaat ctctttggtt tgaactttac tcaaaatcga
    11761 actgcctttc ctgctattat cgctggagca attatctatc tctttacgac tattaaaaac
    11821 tggaaggcct tttggcttag tattggggtc ttcgcgattg gtttgagttt cctcttttct
    11881 agtgatttgg gagttcgaat gggtacttta gactcttcta tggaagaacg catttctatc
    11941 tgggatgctg ggatggcctt gtttaagcaa aatccttttt ggggtgaagg gccattgacc
    12001 tatatgcact cttatcctcg gatacatgct ccttatcatg aacatgccca cagtctttat
    12061 attgatacga ttctgagtta cggaattgtg ggtaccattt tattagtttt gtcttctgtt
    12121 gctcctgttc gcttgatgat ggatatgagt caggagtcgg ggaaacgtcc gattatcggc
    12181 ctttatctat ctttccttac agtggttgct gtgcacggaa tttttgactt ggctctcttc
    12241 tggattcagt caggctttat tttcttgcta gttatgtgca gtattccatt ggagcatcga
    12301 atgttggtat cggacatgac ggattaagtt ttataagttt gaaatcttct accttgggta
    12361 ggagattttt ttatacgatg ggcatgtcgt gcatctgagg tgtaagtcct ctgtagggat
    12421 ccactaccgg tgaatacaat agcgctcccc aagcctgact atcgtgaggt agcggattaa
    12481 aatggtctgg ggatagatcg ttttaagtct gacgcaggaa ataagaattg tcagagaaag
    12541 caatagtgaa atcgtaggct atgaatagaa acgtgatagc gaggagcata tagtggataa
    12601 ggtagcgaga aattttaaag tataaaagat agtcttaatc tatatatgta aatcacaaaa
    12661 gtaattgaat tcggaataag gttggtgtga aaagacatag taaactgaat cttgaatact
    12721 agaatgatac ttctacaata ttgttataat ttaatttgaa ttccaaaatc acattgttcc
    12781 gtccgtattt cattttactg tatgtcttcc taaactccaa agtttctgcg tcaaatttcc
    12841 tattttcact gtagtctttg acacttcgaa cgacaatttg aatcatatat tcaaaaaaaa
    12901 tgaaaaattt gtgccaacaa gcctaaatat tctgaaaatt tgtttgattt ttaatggata
    12961 atgtgatata atggttgtca atctataatt cacataaaca gaggagtaga aaatgaaaaa
    13021 aaatcgtgta tttgctacag caggtcttgt tttattagca gcaggtgtac ttgcagcatg
    13081 cagttcttca aaatcatctg attcatcagc ccctaaagct tatggctatg tttatacagc
    13141 agacccagaa accttggact acctgatttc aagtaaaaat agtacaacag tagtgacttc
    13201 aaatgggatt gatggtttat tcactaacga taattacggt aatcttgctc ctgcagttgc
    13261 agaggattgg gaagtctcta aggatggttt gacctacact tataagattc gtaaaggggt
    13321 taaatggttt acctctgatg gagaagaata tgcagaggtg acggctaaag atttcgtgaa
    13381 cggtttaaaa cacgcagcag ataaaaaatc agaagctatg tatttagctg aaaattcggt
    13441 taaaggcttg gcagattatc tatcaggaac ttcaacagat ttttcaacag ttggtgtcaa
    13501 ggcggttgat gattatacgt tacaatacac tttgaaccag cctgaaccgt tctggaactc
    13561 taagttgacc tattctattt tctgacctct gaatgaagaa ttcgaaacat caaaaggaag
    13621 cgattttgct aaaccaacag atccgacatc cttgctttat aatggtccat tcttgttgaa
    13681 agggttgact gcaaaatctt ctgtagagtt tgtaaaaaat gagcaatatt gggataaaga
    13741 aaatgtctac ctagatacta tcaatctagc ttactatgat ggatcagatc aggagtcgct
    13801 agagcgtaac ttcactagtg gagcttatag ttatgcccgt ctttacccta ccagctccaa
    13861 ctattctaag gttgcagaag aatacaagga caatatctat tacacacaat caggctctgg
    13921 gattgctggt ctgggtgtga atattgatcg ccaaagttac aactatactt ctaaaactac
    13981 agattcagag aaagtagcta ctaagaaggc attgcttaac aaagatttcc gtcaagcctt
    14041 gaattttgct cttgatcgct cagcttactc agctcaaatc aatggtaaag atggagcagc
    14101 tttagcagtt cgtaatttat ttgtaaaacc agactttgtt tcagctggtg agaagacctt
    14161 tggtgattta gtcgctgctc aacttcctgc ttatggtgat gagtggaaag gtgtgaattt
    14221 agctgatggg caggatggtt tattcaatgc tgacaaggcc aaggcagagt ttgcgaaagc
    14281 taagaaagct ttagaagcag acggcgttca gtttcctatt catctggacg ttccagtaga
    14341 ccaagcatca aaaaactaca tatctcgtat tcagtccttt aaacaatctg tagaaacagt
    14401 tcttggtgtt gaaaatgtcg ttgttgatat tcaacaaatg acaagtgatg aattccttaa
    14461 tattacttac tatgctgcca atgcttcatc tgaggattgg gatgtatcgg gaggagtttc
    14521 atgggggcca gactatcaag acccatctac ttacctggat attttaaaaa caactagcag
    14581 tgaaactaca aaaacatatt taggatttga taatccaaat agcccttcag tagttcaagt
    14641 tggtttgaaa gaatacgata aattagttga tgaagctgcc aaagagacaa gcgacttgaa
    14701 tgtccgttat gaaaaatatg cagcggctca agcatggttg acagatagtt cactctttat
    14761 tcctgctatg gcttcttctg gtgcagcacc agtgctttca cgaattgttc catttactgg
    14821 agcttctgcg caaacaggct ctaaggggtc agatgtttac ttcaaatatt tgaaattaca
    14881 agataaagtg gtgactaagg aagagtatga aaaagctcgt gaaaaatggt tgaaagaaaa
    14941 agctgaatca aatgagaaag ctcaaaaaga attggcaagt catgtgaagt aaataatttc
    15001 taatagaact ttctctccat gaggagaagg ttcttttggg atttttaaag gaaataatat
    15061 gaaaaaatat atttttatgc gtgttttgcg gtcattggtt tcgattttct tagtaacgac
    15121 tttgacctac acgattatct ataccttggt tcctcgaaaa ttgattttca agcaggatcc
    15181 taactataat aaaattgcga caacggctga taaacgtgat aactatgaaa atactgtgtt
    15241 tgagcgtatg ggctacattg agtattacga tactaaagag ttgcaagaaa aggcaagtag
    15301 catggattct tctgtaacag tagaagcaaa tgcgaccaat aaagctattt atgaaaagta
    15361 catcaatcaa ttaggtcatg gttggacttt gggagaattt actgaaagtg gtcaattcta
    15421 tgctactcgt gaaattccaa tttttgaacg tgtttttcac ttctatgcta acttgattga
    15481 cattgaccat acaaataaaa tccaagaccc tgaaaatcca gacttgaaac gctaccttcg
    15541 ttttgaaaat gatccagcta tcggatggtc attggtcggt tcaggaacta aacataaata
    15601 tctcttgtac tttaacagtc agttcccatt tgttcatcaa aactttgtga acttgaattt
    15661 aggtgactct tacccaacct atgctaatac accagttctt caggttatta ctcaaggtca
    15721 aggacaaacc aaaactgccc aagttcagtt cccaacaggt aagaaaacgt cttctgtaaa
    15781 tatttactca agaacctaca agtcacctag tcaggctgac tctcgtgaag tagctagcta
    15841 tgggaaagat gatccttata cagcgactga aagtaattac caatatccat ctatgattgt
    15901 cagctctgct attactggtt tgattggttt ggttcttgcc tatgctcttg ccgtgccact
    15961 tggttcagcc atggctcgtt tcaagaacac ttggattgat agcctctcaa cagggacttt
    16021 gaccttcttg cttgctcttc caacgattgc cttggtttac atcgttcgat tgattggatc
    16081 atctattgcc cttccagatt cattccctat cttgggagct ggagattggc gttcttacgt
    16141 tttaccagca gtcatccttg gtttgttggg tgctcctgtt acagccattt ggattcgtcg
    16201 ttacatgatt gacttgcaat ctcaagactt tgttcgtttc gctcgtgcaa aaggtttgtc
    16261 tgaaaaagaa atttcaaaca aacacatctt taaaaatgcc atggttccgc tggtttcagg
    16321 aattcctggt gccattattg gggttatcgg tggtgcaacc cttactgaaa cagtcttcgc
    16381 cttcccaggt atgggtaaaa tgttgattga ctctgtaaaa gcatctaata actctatggt
    16441 cgttggtctt gtcttcatct ttacatgtat ttctatcttc tcacgtcttt tgggagatat
    16501 ttggatgact attattgacc cacgtattaa attgactgag aaaggaggca aataatgtct
    16561 acaatcgata aagaaaaatt tcagtttgta aaacgtgacg attttgcctc tgaaactatt
    16621 gatgcgccag catattctta ctggaaatca gtgtttaaac aatttatgaa gaaaaaatca
    16681 actgtagtca tgttgggaat cttggtagcc atcattttga taagtttcat ctacccaatg
    16741 ttttctaagt ttgatttcaa tgatgtcagc aaggtaaacg actttagtgt tcgttatatc
    16801 aagccaaatg cggagcattg gttcggtact gacagtaacg gtaaatcgct ctttgacggt
    16861 gtctggttcg gagctcgtaa ctccatcctc atttctgtga ttgcgacagt gattaacttg
    16921 gttatcggtg tttttgtcgg tggtatttgg ggtatttcaa aatcagttga ccgtgtcatg
    16981 atggaagttt acaacgtcat ctcaaacatc ccacctcttt tgattgttat tgtcttgact
    17041 tactcaatcg gagctggatt ctggaatctg atttttgcca tgagcgtaac aacatggatt
    17101 ggtattgcct tcatgatccg tgtgcaaatc ttgcgctatc gtgacttgga atacaacttg
    17161 gcgtcacgta ctttgggaac accaaccttg aagattgttg ccaaaaatat catgcctcaa
    17221 ttggtatctg ttattgtgac aaccatgact caaatgcttc caagctttat ctcatacgaa
    17281 gccttcttgt ctttcttcgg tcttggatta ccgattacag tgccaagttt gggtcgtttg
    17341 atttcggatt attcacaaaa cgtaacaacc aatgcttact tgttctggat tccattgaca
    17401 acccttgtct tggtatcctt gtcccttttc gtagttggtc aaaacttagc ggatgctagt
    17461 gatccacgta cacatagata ggagtagaaa tgacaaaaga aaaaaatgta attttgactg
    17521 ctcgcgatat tgtcgtggaa tttgacgttc gtgacaaagt attgacagcc attcgcggcg
    17581 tttcccttga actagtcgaa ggagaagtat tagccttggt aggtgagtca ggatcaggta
    17641 aatctgtttt gacaaagacc ttcacaggta tgctcgaaga aaatggtcgt attgcccaag
    17701 gtagtattga ctaccgtggt caggacttga cagctttatc ttctcacaag gattgggaac
    17761 aaattcgtgg tgctaagatt gcgactatct tccaggaccc aatgactagt ttggacccca
    17821 ttaaaacaat tggtagtcag attacagaag ttattgtaaa acaccaagga aaaacagcta
    17881 aagaagcgaa agaattggcc attgactaca tgaataaggt tggcattcca gacgcagata
    17941 gacgttttaa tgaataccca ttccaatatt ctggaggaat gcgtcaacgt atcgttattg
    18001 cgattgccct tgcctgccga cctgatgtct tgatctgtga tgagccaaca actgccttgg
    18061 atgtaactat tcaagctcag attattgatt tgctaaaatc tttacaaaac gagtatcatt
    18121 tcacaacaat ctttattacc cacgaccttg gtgtggtggc aagtattgcg gataaggtag
    18181 cggttatgta tgcaggagaa atcgttgagt atggaacggt tgaggaagtc ttctatgacc
    18241 cttgccatcc atatacatgg agtctcttgt ctagcttgcc tcagcttgct gatgataaag
    18301 gggatcttta ctcaatccca ggaacacctc cgtcacttta tactgacctg aaaggggatg
    18361 cttttgcctt gcgttctgac tacgcaatgc agattgactt cgaacaaaaa gctcctcaat
    18421 tctcagtatc agagacacat tgggctaaaa cttggcttct tcatgaggat gctccaaaag
    18481 tagaaaaacc agctgtgatt gcaaatctcc atgataagat ccgtgaaaaa atgggatttg
    18541 cccatctggc tgactaggag gaaggaaatg tctgaaaaat tagtagaaat caaagattta
    18601 gaaatttcct tcggtgaagg aagtaagaag tttgtcgcgg ttaaaaatgc taacttcttt
    18661 atcaacaagg gagaaacttt ctcgcttgta ggtgagtccg gtagtgggaa aacaactatt
    18721 ggtcgtgcta tcatcggtct aaatgataca agtaatggag atatcatttt tgatggtcaa
    18781 aagattaatg gtaagaaatc gcgtgaacaa gctgcggaat tgattcgtcg aatccagatg
    18841 attttccaag accctgccgc aagtttgaat gaacgtgcga ctgttgatta tattatttct
    18901 gaaggtcttt acaatcaccg tttatttaag gatgaagaag aacgtaaaga gaaagttcaa
    18961 aatattatcc gtgaagtagg tcttcttgct gagcacttga ctcgttaccc tcatgaattc
    19021 tcaggcggtc aacgtcaacg tatcggtatt gcccgtgcct tggtcatgca accagacttt
    19081 gttattgcag atgagccaat ttcagccttg gacgtttctg tacgtgccca agtcttgaac
    19141 ttgctcaaaa aattccaaaa agagctcggc ctgacctatc tcttcatcgc ccatgacttg
    19201 tcggttgttc gctttatttc agatcgtatc gcagttattt acaagggtgt tattgtagag
    19261 gttgcagaaa cagaagaatt gtttaacaat ccaattcacc catatactca agccttgctt
    19321 tcagcggtac caatcccaga tccaatcttg gaacgtaaga aggtcttgaa ggtttacgat
    19381 ccaagtcaac acgactatga gactgataag ccatctatgg tagaaatccg tccaggtcac
    19441 tatgtttggg cgaaccaagc cgaattggca cgttatcaaa aaggactaaa ctagtaatgg
    19501 ttttataatt tccatgtcaa tttttatgga aattaggctc tttgtcaact gtagtgggtt
    19561 gaagtcagct aagctcgaga aaggacaaat ttcggctctt tgtcaactgt agtgggttga
    19621 agaaaagcta agcttgagaa aggacaaatt tcgtcctttc ttttttgatg ttcagagcga
    19681 taaaaatccg ttttttgaag ttttcaaagt ttcgaaaacc aaaggcattg cg
//
LOCUS       DAVHSI010000036        19586 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.036, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000036 DAVHSI010000000
VERSION     DAVHSI010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.036"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(268..1167)
                     /gene="htpX"
                     /locus_tag="VVR21_001578"
     CDS             complement(268..1167)
                     /gene="htpX"
                     /locus_tag="VVR21_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU6055405.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(1169..1729)
                     /locus_tag="VVR21_001579"
     CDS             complement(1169..1729)
                     /locus_tag="VVR21_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU6055406.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            1823..2536
                     /gene="rsmG"
                     /locus_tag="VVR21_001580"
     CDS             1823..2536
                     /gene="rsmG"
                     /locus_tag="VVR21_001580"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU6055407.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            2790..4073
                     /locus_tag="VVR21_001581"
     CDS             2790..4073
                     /locus_tag="VVR21_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU6055408.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(4268..5839)
                     /gene="ffh"
                     /locus_tag="VVR21_001582"
     CDS             complement(4268..5839)
                     /gene="ffh"
                     /locus_tag="VVR21_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU6055409.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5851..6183)
                     /locus_tag="VVR21_001583"
     CDS             complement(5851..6183)
                     /locus_tag="VVR21_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU6055410.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(6273..6650)
                     /locus_tag="VVR21_001584"
     CDS             complement(6273..6650)
                     /locus_tag="VVR21_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU6055411.1"
                     /translation="MKIRMRNTIQFDEQLEVIDRLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDRQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            6722..8026
                     /locus_tag="VVR21_001585"
     CDS             6722..8026
                     /locus_tag="VVR21_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU6055412.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            8039..8845
                     /gene="yidA"
                     /locus_tag="VVR21_001586"
     CDS             8039..8845
                     /gene="yidA"
                     /locus_tag="VVR21_001586"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU6055413.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(8901..8972)
                     /locus_tag="VVR21_001587"
     tRNA            complement(8901..8972)
                     /locus_tag="VVR21_001587"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8937..8939),aa:Arg,seq:cct)
     gene            complement(9015..9362)
                     /gene="rplS"
                     /locus_tag="VVR21_001588"
     CDS             complement(9015..9362)
                     /gene="rplS"
                     /locus_tag="VVR21_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU6055414.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(9481..9810)
                     /gene="crcB"
                     /locus_tag="VVR21_001589"
     CDS             complement(9481..9810)
                     /gene="crcB"
                     /locus_tag="VVR21_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6055415.1"
                     /translation="MVIVYLAIACGFGALVRYLFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(9804..10178)
                     /gene="crcB"
                     /locus_tag="VVR21_001590"
     CDS             complement(9804..10178)
                     /gene="crcB"
                     /locus_tag="VVR21_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU6055416.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLFKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(10175..10441)
                     /locus_tag="VVR21_001591"
     CDS             complement(10175..10441)
                     /locus_tag="VVR21_001591"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU6055417.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(10557..11000)
                     /locus_tag="VVR21_001592"
     CDS             complement(10557..11000)
                     /locus_tag="VVR21_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU6055418.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            11104..12039
                     /locus_tag="VVR21_001593"
     CDS             11104..12039
                     /locus_tag="VVR21_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU6055419.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            12093..12377
                     /locus_tag="VVR21_001594"
     CDS             12093..12377
                     /locus_tag="VVR21_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU6055420.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(12434..12652)
                     /locus_tag="VVR21_001595"
     CDS             complement(12434..12652)
                     /locus_tag="VVR21_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055421.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(12649..13543)
                     /locus_tag="VVR21_001596"
                     /pseudo
     CDS             complement(12649..13543)
                     /locus_tag="VVR21_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            14229..15575
                     /gene="gdhA"
                     /locus_tag="VVR21_001597"
     CDS             14229..15575
                     /gene="gdhA"
                     /locus_tag="VVR21_001597"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU6055422.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(16081..16251)
                     /locus_tag="VVR21_001598"
     CDS             complement(16081..16251)
                     /locus_tag="VVR21_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055423.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(16264..16905)
                     /locus_tag="VVR21_001599"
     CDS             complement(16264..16905)
                     /locus_tag="VVR21_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6055424.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIFVMKGGKIVESGNHKYLMELGGEYYSLYTKRK"
     gene            17178..17774
                     /locus_tag="VVR21_001600"
     CDS             17178..17774
                     /locus_tag="VVR21_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055425.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTDEKEVNHLI
                     KYAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHTKYQKTQTDFQQEI
                     KVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQRKIDVEPVFGQIKA
                     SLGYKRCNLRGKRQVRIDMGLVLMANNLLKYNKRTTQN"
     gene            complement(17924..18118)
                     /locus_tag="VVR21_001601"
                     /pseudo
     CDS             complement(17924..18118)
                     /locus_tag="VVR21_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(18145..19062)
                     /locus_tag="VVR21_001602"
                     /pseudo
     CDS             complement(18145..19062)
                     /locus_tag="VVR21_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
     gene            complement(19094..19501)
                     /locus_tag="VVR21_001603"
     CDS             complement(19094..19501)
                     /locus_tag="VVR21_001603"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU6055426.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYCPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGASQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
BASE COUNT         5937 a         4231 c         3527 g         5891 t
ORIGIN      
        1 ctaatgagtt gttttgtcgc ttttcattat aggtcatatg ggactttttt tctacacaaa
       61 ataggctcca taatatccat aggggggtta cccactacaa atattataga gccttataaa
      121 tttgcaacat agcagatagg tggggcaaaa acacaatttt aggagaaaaa gaagtaaatc
      181 ttcccatagt aaaacgcata atatcaagtt ttcacacctg atattatgcg tttttcagat
      241 tttaaagact tttttccagc cttcatttta catatgtttt aaacgttcaa tccgttctga
      301 gataggtggg tgggtataaa agagtttttg gaacccccca cctttcttgg gatcattgat
      361 ataaagggca ctgctagcat catcgacgtg gcgactcata ggtttgctat tgtccaactt
      421 atctagggca ttaatcattc cctggggatt gcgagtcagc tcgacactag atgcatctgc
      481 cagaaattcc ctctgacgag aaatagcgag ctgaaccaag gttgcagcga gaggtgccag
      541 tacaatagct agtagggaaa ccactagcat aatgatttca agaccatttc catctcggtc
      601 atcatcactt cgtctgcgac ctgctccacc ccaccacatc atacgacctg ccatactaga
      661 aagcatggtg atagcactag caagggcaac tgcaatagtc gaaatacgga tatcataatt
      721 acgaatatga ctgacttcat gtcccataac agcttctagt tcttcacgat tcatgatagc
      781 tagtagacct gaagtcgcag caacagccgc attttgagga ttagaacctg tcgcaaaggc
      841 atttaaggct ggatcatcaa tgatgaaaac acggggcata ggaatctgag cgaccagagc
      901 catatcttcc actacatggt agaggtctgg tgccgtttgc tcatccacct cacgcgctcc
      961 attcatggac atgacaatct ctgtcgattg aaaaatcata gacaaagcgt agataaagcc
     1021 gataatcagt gcgataacca aaccaccaag tccagatctt ataaagagat aaccaaccgc
     1081 ataaccaaca agagctaaga gtaggaaaaa taccagcaac aaaatccagg tttttcgttt
     1141 attgcttgca atttgatcaa acaacatctt agtcacctaa accgctaaaa tcaactttag
     1201 gaaccgactt ttcctcttca ggtgtttgaa ggaaatctgc cgctttaaat ccaaacattc
     1261 cagcgataat attgctcggg aaagtttcta attttacatt gtagttgctg acaacactgt
     1321 tatagagttg acgagagtaa gaaattttat tttctgtatt tgtcaactcc tcttgcaatt
     1381 taacaaagtt agcactagct ttcaaatctg gatagctttc tgcaactgca aaaatacctg
     1441 aaacctgacg agtgagggca tcactggctt tcatagcttc tgctggtgaa gtcgctgccg
     1501 ccacttggtt acgtagttct gccacctttt caagggtaga accttcatat ttggcataac
     1561 cttttacagt ctcaatcaag tttggcaaga gatcattgcg acgttttaac tgaacatcaa
     1621 tctgactcca agcctccttg gtttgcatac gatttttaac caaaccgtta tagctaacaa
     1681 tcacaaaaat aacaacaaga gctaaaactc caagaataat ccaagtcata atataagtcc
     1741 tttctgcttt tagattagta ccagtatatc aaattttcta tgattgtggt aaaataagat
     1801 gatactaaag aaggaaataa ctatgaaacc aaaaacattt tacaacttgc ttgccgagca
     1861 gaatcttcca ctttcggacc agcaaaaaga acaatttgaa cgttattttg agctcttggt
     1921 cgagtggaat gagaagatta atttgacggc gattacggac aaggaagaag tttatctcaa
     1981 acatttttac gattcgattg cacccattct tcaaggtttg attcccaatg aaactatcaa
     2041 acttcttgat atcggggctg gggcaggatt tcctagtcta ccaatgaaaa ttctctatcc
     2101 ggagttagat gtgaccatta ttgattcact caataagcgc atcaacttcc tacaactctt
     2161 ggctcaagaa ctggatttga acggagttca tttctaccac ggacgtgccg aagattttgc
     2221 ccaagacaag aacttccgtg ctcaatatga ttttgtaaca gctcgtgcgg ttgcccgtat
     2281 gcaggtccta tctgaattga ctattcccta ccttaaggtt ggtggcaaac tattggcact
     2341 caaggctagc aatgcgcctg aggaattatt agaagctaag aatgccctca atctcctttt
     2401 tagtaaggtc gaagacaatc tcagctacgc cctaccgaat agagatccgc gctatatcac
     2461 agtggtagaa aagaaaaaag aaacaccaaa taaatatcca cgtaaggctg gtatgccaaa
     2521 taaacgccca ctttaaattt tttagtaaac aaatgtttac aaaatcagcc tcgctctttt
     2581 atttctaggc tcgggaaaaa atgatttaca aaatcatttt tttctgctat actatcctaa
     2641 gcaaaggttt ttaatgtcat cccgtgaggt gacgaagacg cagaaatatt taaaactctt
     2701 taaaatctaa attttaaaga agtcttactc tgagggccta ttgctgtaaa ataatgggct
     2761 cttttctgat gcccaaaagt gaggtttata tgaaacaaga atcaactgtt gatttgttac
     2821 tagacgttga ccaacgtcct tcggatggaa aaggaattct ccttagcttc caacacgttt
     2881 tcgccatgtt tggtgcgacc atcttggtac cattgatttt gggaatgcct gtatctgttg
     2941 ccctttttgc ttcaggtgtt ggaacactca tctacatgat tgctactggt tttaaagttc
     3001 cagtttatct aggttcttca tttgccttta tcacagctat gtcactggct atgaaagaaa
     3061 tgggggggga tgtatctgct gcccaaacag gggttatctt gactggtttg gtctatgtcc
     3121 ttgttgctac cagcatccga tttgtaggaa caaaatggat tgataaactc ttgccaccaa
     3181 tcattatcgg tcctatgatc atcgttatcg gtcttggact tgcaggttca gctgttacca
     3241 atgcaggtct tgtagcagac ggaaattgga aaaatgctct ggtagccgtt gttactttcc
     3301 taattgctgc ctttatcaat acaaaaggaa aaggcttcct acgaatcatt ccattcctct
     3361 ttgccattat cggtggttac ctcttcgcac taactcttgg tttggttgac tttacgcctg
     3421 tcctagaagc taactggttt gaaattcctg gtttctactt gccatttagc acaggtggtg
     3481 cctttaaaga gtacaatctt tactttggtc cagaagccat cgctatcttg ccaatcgcta
     3541 tcgtaacaat ttctgaacat atcggagacc atactgtttt gggtcaaatc tgtggccgtc
     3601 aattcttaaa agaaccaggt cttcaccgta ctcttattgg tgacggtatc gcaacttctg
     3661 tttccgcctt ccttggtgga ccagccaata caacttacgg agaaaataca ggggttatcg
     3721 gtatgactcg tatcgcttct gtctcagtta tccgtaacgc tgccttcatc gcgattgccc
     3781 tcagcttcct tggtaaattc actgccttga tttcaactat tccaaacgct gtacttggtg
     3841 gtatgtcaat ccttctctat ggggttatcg ccagcaatgg tttgaaagtc ttgattaaag
     3901 aacgtgttga tttcgctcaa atgcgaaacc tcatcatcgc aagtgctatg ttggttcttg
     3961 gacttggagg agctatcctt aaacttggtc cagttacact ttcaggtact gccctttcag
     4021 ccatgacagg aatcatcttg aacttgatct tgccatacga aaataaagac taagagtcta
     4081 aatacaccta atccactcag acagctgagt ggatttttcg tataccataa taaaagtgtc
     4141 ttaacaaagt tattaaaatc aaaaaacgta taatatcaga tattctaaaa ccttgatact
     4201 gtacgtttta tcatagaaat ttttacttta ttttctcatc aaatgagatt tgcatcaatc
     4261 tcttgtctta cttgcgtttc ttcttcgctt tcttcatttt gttagccata cgtttcatgg
     4321 actgtttcat agcaaattca ccaattttac ctttcaaacc gccaccaaac atctggctca
     4381 tatctggcat tcctgctcct ccgagagctg ataagtcagg cataccgcct tgtcccatca
     4441 ttccttcaag ggcagacata tccattcctc ccatatttgg catattttta ggaaggttat
     4501 ttggattaat ccccatttgc ttcatcattt tattcatatc cccagacata acaccctgca
     4561 tgagctgttt agcctggtta aagtccttga tgaatttatt gacttcgacg aatgtatttc
     4621 cagaaccagc agcaatacga cggcgacggc ttggatttaa caaatctggg ttttcacgct
     4681 cttcaggtgt catcgaagac acaatggcac gtttacgagc aatctggcgt tcatccacct
     4741 tcatgttttg aagggctgga ttgtttgcca tacctggaat catcttgagc aagtcttcca
     4801 tcggccccat attttgcacc tgatctaatt gatcgatgaa atcattaaaa tcaaaggtgt
     4861 tttcgcgcat cttctcagcc atttcaaggg ctttttgttc atcgtattcc tgagaagctt
     4921 tctcaatcaa agtgagcata tcccccatac caaggatacg gctagacatg cggtctgggt
     4981 ggaaggtttc aatgtccgta atcttttcac ctgtaccagt gaacttgatt ggttttccag
     5041 taatgtgacg aacagacaga gcagcaccac cacgagtatc gccatcaatc ttggtaagga
     5101 tgaccccagt cacttccaac tgagcattaa actcacgcgc aacattggct gcttcctgac
     5161 caatcatagc atcaacgaca agcaagattt catttggttg agccaatgct ttcacatcac
     5221 gaagctcatt catgaggagc tcatcaatct gcaaacgacc cgcagtatca atcaagacat
     5281 agtcgttatg attagtttgg gcttgctcca aaccttgacg tacaatctca acagctggta
     5341 cttctgttcc aagtgcaaag acaggcacat caatctgttg tcccaaggtc ttaagctggt
     5401 caatggcagc tggacgataa atatccgccg caatcatcaa aggacgagca ttttcttctt
     5461 tcttgagttt gttggccaat ttaccagcaa aggttgtttt accagcccct tgtaaaccaa
     5521 ccatcatgat gatggttgga atcttaggtg acttgataat ttctgccgta tcagaaccta
     5581 aaacggctgt cagttcctca tcaacgattt taataatctg ttgcgcagga ttaagtgtat
     5641 caatgacctc atgcccgact gcacgctcac gaactttctt gataaagtcc tttacaacag
     5701 gcaaggcaac gtcggcctcg agcaaggcca agcgaatttc tttggttgcc tcttggacat
     5761 cagattcaga gatttttcct tttttacgta gatttttaaa gacgttctgc aaacgttctg
     5821 ttaaactttc aaatgccatt tttcttcctc ttattctcta ttatcaatgc ttgttaaaat
     5881 ttctatctgc tcctgcagaa aatcatcctt gggatagcgc tccaagattt ggtcaaaaat
     5941 ctgactacgg acaatgtagt ccgagtacat gtgcaatttc atctcataat cttccagaat
     6001 cttttctgtt cgcttgatat tgtcatagac agcctgacga ctaacaccaa actcctcagc
     6061 tatctcagca agactgtaat catcagcgta gtaaagctct atataattca tttgcttatc
     6121 tgtcaaaagc gccgcataaa attcaaagag cgcattcata cgattggttt tttcgatttc
     6181 cataactttt attataccaa aaaatagcct aatctaccac actagggagc caatccttga
     6241 agatagaaag tagatttgag aaaaacgaga tcctagcccc aagtaatttc caattgatag
     6301 ctggcaaagg gatgcccctc ttgattttgt agttgataag ctagctcaat cttttgccta
     6361 tcaacttgat aacggctcgt ttgaatgata aattcctgca tgcccatagg ggtaggaata
     6421 taggccaaac tatcactatc ctttaaaaag cgcataatgg tcttgggatt agaaaatcgg
     6481 ctcatcacca gttcttgacc atgaaattta atcactactt tttccttttc ctcattatag
     6541 aaaagcaggt agctataatc tcctttttca tgcacttcca catcataaag ccggtcaatc
     6601 acttccaact gctcatcaaa ctgaattgta tttcgcatcc gaatcttcac atcaggccct
     6661 ctttcttgtc tcttgtccta ctattttacc aaaaagagca ggattttgct ataatggtca
     6721 tatgaacgaa aaagtattcc gtgacccagt tcacaactac atccatgtca ataatcaaat
     6781 catctatgac ttgattaata caaaagaatt tcagcgtttg cgccgtatca agcaactggg
     6841 aacctccagt tataccttcc acggtggaga gcacagccgc ttctctcact gtctaggagt
     6901 ctatgagatt gcacgacgta tcacagaaat ttttgaagaa aaatatcctg aggaatggaa
     6961 tcctgccgag tctctcttga ccatgaccgc tgctctccta catgaccttg ggcatggcgc
     7021 ctactcccat acttttgaac atctctttga tacagaccat gaagccatta ctcaggagat
     7081 tattcaaaat cctgagacag agattcacca agtcttgcta caagtagcgc ccgattttcc
     7141 agaaaaagtt gccagtgtca tagaccatac ctatcctaat aagcaggtcg tgcagctcat
     7201 ttctagtcag attgacgcag atcgcatgga ctatctcttg cgcgactcct attttacagg
     7261 agcatcctat ggggaatttg acctgactcg catcctccga gtcattcgtc ctgtcgaaaa
     7321 tggtatcgcc tttcagcgca atggcatgca cgccatcgaa gactacgtcc tcagtcgcta
     7381 ccagatgtac atgcaggttt atttccaccc agcaacacgc gccatggaag ttctcctaca
     7441 gaatcttctc aagcgcgcca aggaactcta ccctgaggac aagaatttct ttgcacgaac
     7501 ttccccacat ctcctgcctt tcttcgaaaa aaatgtgacc ttgactgact atctggctct
     7561 ggatgatggc gtgatgaata cctacttcca gctttggatg actagtcctg acaaaattct
     7621 tgcagattta tctcaacgct ttgtcaaccg caaggtcttt aaatccatta ccttttcaca
     7681 agaggaccaa gatcaactta ctagcatgag aaaattggtt gaggacatcg gctttgatcc
     7741 cgactactat actgccattc ataagaactt tgacctccct tatgatatct atcgtcccga
     7801 atctcaaaat ccacggacac agattgagat tttacaaaaa aatggagaac tggccgaact
     7861 ctctagcctg tctcctatcg tccaatccct tgctggcagt cgccacggag ataatcgctt
     7921 ttattttcca aaagaaatgt tggaccaaaa cagcatcttt gcaagcatta cccagcaatt
     7981 tttacacttg attgagaacg atcattttac cccaaataaa aactagaaga ggaattttat
     8041 gagtattaaa ctaatcgctg tcgatattga cggaacccta gtcaacagtc aaaaggagat
     8101 tactcctgaa gtcttttctg ccatccaaga tgccaaagaa gctggtgtca aagtcgtgat
     8161 tgcaactggc cgccccatcg caggtgttgc caaacttctg gacgacttgc agttgagaga
     8221 ccaaggtgac tatgtggtga ccttcaatgg tgcccttgtc caagaaactg ctactggcca
     8281 tgagattatc agcgaatcct tgacctatga ggattatctg gatatggaat tcctcagtcg
     8341 caagctcggt gtccacatgc atgccattac caaggacggt atctatactg caaatcgcaa
     8401 tatcggaaca tacactgtac acgaatcaac cctcgtcagc atgcctatct tctaccgtac
     8461 ccctgaagaa atggctggca aagaaattgt taaatgtatg tttatcgatg aaccagaaat
     8521 tctcgatgct gcgattgaaa aaattccagc agaattttac gagcgctact ccatcaacaa
     8581 atctgctcct ttctacctcg aactccttac aaagaatgta gacaagggtt cagccattac
     8641 tcacttggct gaaaaactcg gattgaccaa agatgaaacc atggcaatcg gtgacgaaga
     8701 aaatgaccgt gccatgctgg aagtcgttgg aaaccccgtt gtcatggaaa atggaaatcc
     8761 agaaatcaaa aaaatcgcca aatacatcac taaaacaaat gacgaatccg gcgttgccca
     8821 cgccatccga acatgggtac tgtaaaagga aagaatagac taaaaccgct cagctgagcg
     8881 gtttttgata tctaattaca tgccccctgc aggaatcgaa cctgcaacta ctccttagga
     8941 gggagttgtt atatccattg aactaaggga gctagataaa aactctgctg aaaaagcaga
     9001 gttttttagt cgaattaacg acggatttct ttgatacgag ctgccttacc ttgaagagca
     9061 cgcaagtagt acaatttcgc acgacgtact ttaccgtaac gtacaacttc gattttttca
     9121 acacgtggag tgtggattgg gaagatacgc tcaacaccta caccgttaga gattttacga
     9181 actgtgtagt tttcagagat gccagcacct ttacgtgcaa taacaacacc ttcaaaaatc
     9241 tggatacgtt cacggttacc ttcgacaact ttcgcatgta cacgaacagt gtcaccagga
     9301 cggaatgatg ggatatctgt acgaagttga ccttcagtca agctttggat taatggattc
     9361 attttattct cctatctttg tcaatcttga ggaatcttcc tcagcggata aactgtattt
     9421 ttgtgcgtcc attacacaca agatatagtt taccaaattt ctaaaaaaaa gtaaagaaat
     9481 ttatagcaaa attcctaaaa aaatcgcaac caaaccacct atgtaagtca aagtcaggta
     9541 agaataaaag accttcttat cacttagcag tctttgaagt tcgtcattca aggtcgaaaa
     9601 agttgttaaa ccgccacaaa atcctgttgc tagaatagca tatacttcct tagactctac
     9661 atgattgtaa aatactccaa ttaaaaaaca acctaaaaga ttagctatga gcgttccgag
     9721 tggcaattta gaagcttgat tatagcgaga aaataaatag cgcactaaag ctccgaaacc
     9781 acaagcaatt gcaagataga cgattaccat ttcttcctcc ctagaaaata agctaagagt
     9841 aggcctccac cgatgctcaa aagcaaatac aggactaaac taaaataacg ccctgtatca
     9901 agcagcttca cagtatcaag cattaggctg gaaaaagttg ttaaacctcc gcaaaaaccc
     9961 gtccccagtg ctaaaatcaa gcccttacta gtccccttat agaccagata gcccttgaaa
    10021 agaaaaatca agcagaaaat tcccagatag ttgacaaaga gagtgcccca aggaaagtct
    10081 ggactggctg gtaaccaggt ggaaactaga tatcggacaa gtccgcccaa catagcagct
    10141 agaaaaattc ctagcggata aaattgttct tttttcattt gatattttga tcctgataat
    10201 cacgcgaacg tttgagtatg tccgaaaaag tcgctacaat agtctcctga tagcgcttgt
    10261 cctctacacg actcccaacc ttttcaaaaa taacttcttc tctcttagta tctaaaatcg
    10321 gtttacctga agctttctta taagcaacca ccccctcaac taaatgcatt cgttcttcta
    10381 acagtttgac aatttggtcg tcgatttgat cgatttcttg acgaataata tctaaatcca
    10441 tacagtctcc tcctttattt gaattattgt atcaaaaagc catcaattag gctagtaaaa
    10501 tcccaactct cgataagaaa aatgcactga ttgattacat cagcgcactt ttatgcttat
    10561 cctactttag caaccaattc ttctgcgaat tgttccaagc gttcaatatc ttcttcctcg
    10621 gcagaaagat caactttgac acactcagaa cctttttctg ctcctgttga aacaaagaca
    10681 cggtcaaagt catcaacagc cttacagaat tcatcgtaga aggtatctcc tgagccgacc
    10741 actccgtaga ttttgccatt caagttgaga tctgctagat cttcgtagaa gtccatcatc
    10801 tcatctggca attcaccatc accataagta taggtcgcaa cgatagcgat gtctgcttcc
    10861 aagaagtctg aagcgtcaac agttgtacat tcatcaacat caacatccaa gcccaagtca
    10921 cgtaatttgt ctgctacaat atctgcaatt tcttcggtat taccggtcat actggcaaat
    10981 acaatttttg ctaatgccat atcgtcctcc tcaatttatc tttctccatt atatcacatc
    11041 tttttcattt taaaaataaa aattcttgtg ctacaatgaa atgagaaaga attgaggtta
    11101 tttatggaga tttgccaaca aattttagaa aaaattaaag aatacgacac cattatcatt
    11161 catcgtcata tgaaaccaga ccctgatgcc ttgggaagtc aggtgggatt gaaagccttg
    11221 ctggaacatc atttcccaga aaaaaccatc aaagccgtcg gttttgatga accaactctt
    11281 acttggatgg ctgagatgga tcttgttgaa gatagagcct accaaggcgc acttgtcatc
    11341 gtctgtgata cagctaatac tgctcgtatc gatgataagc gctatagtca aggtgatttt
    11401 ctcattaaga ttgaccacca tccaaatgat gatgtatacg gtgacctgtc ttgggtcgat
    11461 actagttcaa gtagcgctag cgagatgatt accctatttg cccaaacaac ccaactagcc
    11521 ttggcagatc gcgatgctga gttgctcttt gcaggaattg tcggtgatac aggtcgcttc
    11581 ctctaccctt ctaccactgc acggactctt cgcctggctg cttatttgag agaacataac
    11641 tttgactttg cggctctcac tcgcaaaatg gacactatga gctacaaaat tgctaaactg
    11701 caaggctaca tctacgacca tctggaagtg gatgaaaatg gtgctgctcg cgttatcctg
    11761 agtcaagaag tcttgaaaca atacaatgta accgatgctg aaactgcagc cattgtcggt
    11821 gcacctggac gcattgacag agtgagtctc tggggaattt ttgtcgaaca ggctgatggc
    11881 cactaccgag ttcgcttacg cagtaaaatc catcctatca atgaaattgc caaggagcat
    11941 gatggtggag gccaccctct agcaagtggt gctaattcct atagcctaga agaaaacgaa
    12001 atcatctacc aaaagttaaa aaacttgctt aaaaactgat aaaatacttg ccaaactttt
    12061 cagaatctga tagactagta tggtaacaat ctatggctcg caaagagacc atggcagaaa
    12121 ggaaatattg caaaatgaaa aaagatatcc atccagaata tcgcccagtt gtcttcatgg
    12181 acacaactac tggttaccaa ttccttagcg gttcaacaaa acgctctaac gaaacagttg
    12241 agttcgaagg cgaaacttac ccattgatcc gtgtggaaat ttcatcagac tcacacccat
    12301 tctacactgg acgtcaaaag ttcactcaag cagatggacg cgtggatcgt ttcaacaaaa
    12361 aatacggtct caaataatga taaaagaaca gtttcgactg ttcttttttg tttcttgaaa
    12421 tcaactgctg ttttcatgtt ccagactcat ctgtaggttc ggtttccatg ctactaggca
    12481 ggaaggaaat agctgtttca acacgtccat aatgagctgt gctattgtca cgaaccacac
    12541 tttcattgat ggtccaagtg gaattcattt tcttaaaagc ttctcggact ttttccaaat
    12601 ctttggaggc aatggcctgc tctaaggttt caaaacgagg acttatactc atctgctttc
    12661 acaaagcatt ctagtccatc tccgattaac gatggacttt atcacctcct tctccagtcc
    12721 ttgtatgaca tcttgaagtt gattcatgat atcttccaaa gttcgaaagg ctttattctt
    12781 aaatccacgt ttacgaatct ctttccacac ttgttcaatg gggttcatct ctggtgtgta
    12841 tggaggaata aatgcaaaac caatattagt cggaatcttt aaggtacttg atttatgcca
    12901 tatagcattg tccataacga ataaaagata atcatctgga taagcttgtg aaagctcttc
    12961 taaaaaggca ttcatccact cagtattaca tctaccagct attaagaaaa atgattcgcc
    13021 tgtatgggca tcaacagctc cataacaata gcgaaattct cgtatatagt gactatggac
    13081 atgtggacct actcctattg gagaccaaca agatcccagt ttactgattc taccgaaacc
    13141 agcctcatct tggtacatca agcgaacctt atgaaaacgt ctactggttt taaagcgctt
    13201 tcttgtcttc ttgaattgag attttatttt tagacgcgac aatggtttga gcgtctgctt
    13261 tcttaggatg ttctggacgt ggcataatat ttcgccaacc atggcgcttc aacagttgat
    13321 agaaggcatc acgtgtgtag gaacgatata agcctgaaat aaggtattgt aacaaattct
    13381 cctgcctctg tagccttcaa atggcgggca agaaaggctt tctcttcctc aactgtcata
    13441 tatgcatggt tacgaccacc acgtgtttct tgaaggagag agtcgagtcc gaactcctca
    13501 tattttttac atttcgccaa atcgttgttt gattacagtc tatagtgtat tgaatctata
    13561 atagtacacc ttgactacta aaatatttct ataaattaat ttgactttcc tgatagagtt
    13621 gttcacatct tatttcaaat cactataaaa gctctataat ctctttataa gatttgccca
    13681 tcagacgaaa tataataaat tgaaactaga atagtacacc tctacttcta aaacattgtt
    13741 agaaatcgat ttgactgtcc taatcgattt gtcctgttct tgtttcattt tactatagaa
    13801 cgatttgaag gcgtttatga tatttagctg tacgagagtc ttttaaaagt gttttgatgg
    13861 cttggatttc ttctttagtt aatttcatat cactattata taatgatttt tgattttagt
    13921 ctggtataaa tattgctttc ctccaaaatg gtcataattt tactagcaaa tctaacatat
    13981 cacggataaa ttaacaagtg atttctgaat tgctaaacat tttcttttct tatagcatac
    14041 catactttaa gattttgtct ttgagaaaga tatttccaag aaaaacgttc gtttttttat
    14101 ctattttcaa aaaaaccaaa aactgaattg aaagaatttt tagaaaattt ctgttttttc
    14161 tttacagtga aaaaaaattc tgctataatg tcttatgtaa taaaatatga caataaaagg
    14221 agaacgatat gacatctgct aaagaatata tccaaagcgt gtttgaaact gtgaaagctc
    14281 gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga atttttcaac actttggaac
    14341 ctgtatttga aaaacaccct gagtatatcg aagaaaatat cttggcacgt attactgagc
    14401 ctgagcgcgt ggtttctttc cgtgttcctt gggttgaccg tgatggaaaa attcaagtaa
    14461 accgtggtta ccgtgttcaa ttcaactcag ctgttggacc atacaaaggt ggacttcgtt
    14521 tccacccaac tgtaaaccaa gggatcttga aattcctcgg atttgaacaa atctttaaaa
    14581 atgtcttgac tggacttcct atcggtggag gtaaaggtgg atcagacttc gatcctaaag
    14641 gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt catgactgaa ttgcaaaaac
    14701 acatcggacc atcacttgac gtacctgctg gtgatatcgg tgttggtgga cgtgaaattg
    14761 gttaccttta cggtcaatac aaacgtctta accaatttga tgctggtgtc ttgactggta
    14821 aacctcttgg atttggtggt agcttgattc gtccagaagc aactggttac ggtttggttt
    14881 actatactga agaaatgctc aaagctaacg gtaacagctt tgctggtaag aaagtcgtta
    14941 tttcaggttc tggtaacgtt gctcaatatg ctcttcaaaa agcaactgaa ctcggtgcaa
    15001 ctgttatttc tgtttctgac tcaaatggtt atgtcatcga tgaaaatggt atcgacttcg
    15061 atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt gactgagtat gcagctgaaa
    15121 aagcaactgc aacctaccac gaaggtactg tatggactta cgctggaaac tatgacattg
    15181 ctcttccatg tgccactcaa aacgaaatca acggtgaagc agctaaacgt ttggttgctc
    15241 aaggcgttat ctgtgtatct gaaggtgcca acatgccgag cgaccttgat gccatcaaag
    15301 tttacaaaga aaatggtatc ttctacggac ctgcaaaagc tgccaacgct ggtggtgtag
    15361 ccgtttcagc ccttgaaatg agccaaaaca gccttcgcct ctcatggact cgtgaagaag
    15421 ttgatggacg tctcaaagac atcatgacca acatctttaa cacagctaaa acaacttcag
    15481 aaacatatgg tcttgataaa gactaccttg caggagctaa cattgctgcc tttgaaaatg
    15541 tagcaaacgc tatgattgca caaggtattg tttaagattt atttactcaa tcctcaatca
    15601 ctacgattgg ggatttttag cttgaattaa aaaattggaa aatctaatta aataaaatga
    15661 aatgaaataa aaactgaaca aattgattgc ggaattcaaa ccaatttcta acatatttct
    15721 agaaattaat ttgacttttc taatcgattt gttcatatct tatttcaatt tactatactt
    15781 acttaaccct ttttatactc aatgaaaatc aaagagcaaa ctaggaagcg agccgcaggc
    15841 tgtacttgag tacggcaagg caaagctgac gtggtttgaa gagattttca aagagtatta
    15901 aacaaaaaga aaaaccgcta ctcctaagaa tagcgattta atcatatttt taagctacta
    15961 ctgtaattgc tctattattt aagtgttatg aataacttca atatctttaa agctttttgt
    16021 tagatttata attccaacta tagccatctc tactccttag tttacagcaa aaaattatgc
    16081 ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat tcaacaagcc
    16141 taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaacacta ttccaatcat
    16201 cacccctagt gaggctgttg ttaaaattac atattcattt tctttcttca ttttctttac
    16261 acctcatttc ctttttgtat ataagctgta gtactctcca ccaagctcca ttaagtactt
    16321 atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataatat ccgcatcctt
    16381 aatcgttgac aatctatgag ctacaattat ttgagtacag ccctgacttt ttatatactt
    16441 tgttattctt tcctcattaa tagtgtctaa agcactagtt gcttcatcta aaattacaat
    16501 actaggatta tttattaatg cacgtgccag tgctatccgt tgtctttgac cacctgaaat
    16561 atttgaaccc atctctgaga ttatagtatt aaatttcatc ggcatagcca tgatttcatc
    16621 atagatttga actgctttac aaacttcctc tatcttttgt gaagtaactt cgtgctttaa
    16681 agttatatta tcaagaatac ttcggttcaa taaaaacgaa tcctgtggaa ctactcctaa
    16741 attttgactt aatatttttt tatctatttg attaatattt acaccatcaa ataaaacttt
    16801 tcctgtatca atcttatata atcctgatgg tatttttgat aatgtacttt ttcctgaccc
    16861 cggttgaccg actagtgcaa ttctctgtcc tgactcaata gtcaaattta aattttctat
    16921 tacaggagct gagtctttgg aataagagaa agataggtcc ttaatatcta ttctacttca
    16981 aacgtttcta aactatactc cggaaaataa tttaaccaat aactatcttt catcgtatcc
    17041 tccaaccagt actaagagtc tgggacaata gtctcttatc tccaaaaaag aagcggattt
    17101 gccgttgctt ttttgcatgg ttgcgatagt cttggtaaaa tagaattgcc caataaacca
    17161 tttagaaagg ctatcccatg catattcact ataacacaaa tcaaacaact ttaccactag
    17221 aaatcagttc tttcttgccg caagaccatc tcgtctttac tattgaaaaa gtggtgaata
    17281 ccgatgaaaa ggaggtaaac catctgatta aatatgccat gtttgataag gaacaaaaga
    17341 gaggctataa acagtcagct agaaacttag cgaattggca ctataatgac aaggaggata
    17401 gctatacaca tcctgatggc tggtattatc gttttcacca taccaaatat cagaaaacac
    17461 agacagactt tcaacaagaa atcaaggttt actacgccga cgaacctgaa tcagcccctc
    17521 aaaagggact gtatatgaac gaacgctatc aaaacttgaa agctaaagaa tgtcaggcgc
    17581 ttttatctcc ccaaggtaga cagattttcg ctcaacgcaa gattgatgtg gaacctgtct
    17641 ttgggcagat aaaggcttct ttgggttaca agagatgtaa tctgagaggc aagcgtcaag
    17701 tgagaattga catgggattg gtacttatgg ccaataacct cctaaaatac aataagagaa
    17761 cgactcaaaa ttaaaaagct agagttccac aattggaaat ctttagcttt tttgtgattg
    17821 agaactattt tgtcctagac tcttttgatt tttaaagaga acttaaatca ttctctaatt
    17881 aaagtaggaa gaatacacta atttagtaaa gtaaatatta aatttatttt attttaaaat
    17941 gatagtaggc tccaagcata ccagcagtgt tttgatgatg agcaaattct aatcttgtgt
    18001 tctcagccaa acttggaacc aaggcttctt tcaaggctgc acgaatcttt ggtttgagga
    18061 tagcttcttg tcccatgata ccacccccga gaatgaccac ctctggattg acaacgtagt
    18121 gtgtcataaa tacctcctta tggattagag gaagcgctcc ttggtttcac gaatcaaggc
    18181 tgcagccgct tctacaactg gacgatcttc ttcagtcact ggtgtcaatg gtgaacgaac
    18241 agatccaata gtcaagcctt cattgatttt caaaacttct ttgatgacac cgtacatatt
    18301 tccatgagca gaagtgagtt taccaatgat tgcgttgata gcatactgca attcacgcgc
    18361 tgtttctagg tccttatccg caatcaactg attgagtttc aagaagagtt ctggcatagc
    18421 accataagta ccaccgatac cagccctagc acccatgagg cgtcctccta gaaactgctc
    18481 atcaggacca ttaaagacga tatggtcttc cccaccaagg ctgacaaagg tttggatatc
    18541 ttgaactggc atagaagagt tcttaacacc gataacacga ggatttttca acatttctgt
    18601 gtaaaggctt ggagtcaaag caacccctgc caattgagga atgttgtaaa tcacgtagtc
    18661 tgtgtttgga gctgcagaac tgatatcgtt ccagtatttg gcaactgagt attctggcaa
    18721 gcggaagtaa attggtggaa tcgttgcaat agcatctact cccaagcttt cagcatggcg
    18781 aacaagttcc atactatctt tagtattatt gcaagcaaca tgggcaataa tggtcaattt
    18841 acctttggct accgccatga cttcttccaa aatcaacttg cgatcttcaa cgctttggta
    18901 gatacattca ccagaagaac cattgacata aagaccttga acacctttat caatgaagta
    18961 ttgaacctag gcacgcgtac gctctggact tacttctcct tgctcatcat aacatgcgta
    19021 gaaggctgga atgacacctt cgtatttttt caaatctgac attgtttttt tctccttatt
    19081 tcatactacg taattacatt tctagacttg agaacgaata tgggactaat tcctctaatc
    19141 gcaattcaag tatgtttccc ttaccattta atagaaagac taaggtatca ggctcacaaa
    19201 attctaccat aacttgacga caaatgttgc atggtggtaa gtagtcttca gtttcacctg
    19261 caacagcaat cgcaagaata tctccttttc tatatccttg agaagcccca taaaaaatag
    19321 cactacgttc tgcacagtta gttacaccaa acgatacatt ttctatattt gctcctgtaa
    19381 ttactttacc atctttaaat aaaattgctg cacctacagg aaatttggaa tacggacagt
    19441 aagcattttt taaaactttt tttgcttgct ccattaaaac aaatttatta attactgtca
    19501 ttgttttaac tcctttatta ttatatttta ctcacactaa attatagtaa aatgaaataa
    19561 gaacagtaca aatcaatcag gacagt
//
LOCUS       DAVHSI010000037        18969 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.037, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000037 DAVHSI010000000
VERSION     DAVHSI010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.037"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(140..1126)
                     /locus_tag="VVR21_001604"
     CDS             complement(140..1126)
                     /locus_tag="VVR21_001604"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU6055427.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIIRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            1320..3788
                     /gene="gyrA"
                     /locus_tag="VVR21_001605"
     CDS             1320..3788
                     /gene="gyrA"
                     /locus_tag="VVR21_001605"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU6055428.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            3788..4531
                     /gene="srtA"
                     /locus_tag="VVR21_001606"
     CDS             3788..4531
                     /gene="srtA"
                     /locus_tag="VVR21_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU6055429.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            4775..5572
                     /locus_tag="VVR21_001607"
     CDS             4775..5572
                     /locus_tag="VVR21_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU6055430.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            5720..5842
                     /locus_tag="VVR21_001608"
     CDS             5720..5842
                     /locus_tag="VVR21_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEU6055431.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            5864..6904
                     /locus_tag="VVR21_001609"
     CDS             5864..6904
                     /locus_tag="VVR21_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU6055432.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            7075..8349
                     /locus_tag="VVR21_001610"
     CDS             7075..8349
                     /locus_tag="VVR21_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU6055433.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVRHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            8359..9237
                     /gene="truB"
                     /locus_tag="VVR21_001611"
     CDS             8359..9237
                     /gene="truB"
                     /locus_tag="VVR21_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU6055434.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERSERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEDATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            9478..9780
                     /locus_tag="VVR21_001612"
     CDS             9478..9780
                     /locus_tag="VVR21_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU6055435.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            9888..10526
                     /gene="udk"
                     /locus_tag="VVR21_001613"
     CDS             9888..10526
                     /gene="udk"
                     /locus_tag="VVR21_001613"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU6055436.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            10654..11994
                     /locus_tag="VVR21_001614"
     CDS             10654..11994
                     /locus_tag="VVR21_001614"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU6055437.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEVKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            11972..12184
                     /locus_tag="VVR21_001615"
     CDS             11972..12184
                     /locus_tag="VVR21_001615"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU6055438.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            12181..13056
                     /locus_tag="VVR21_001616"
     CDS             12181..13056
                     /locus_tag="VVR21_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU6055439.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQIPFE
                     TESIVSVVESLRING"
     gene            13049..13864
                     /locus_tag="VVR21_001617"
     CDS             13049..13864
                     /locus_tag="VVR21_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU6055440.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            13857..14288
                     /locus_tag="VVR21_001618"
     CDS             13857..14288
                     /locus_tag="VVR21_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6055441.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            14295..15962
                     /gene="recN"
                     /locus_tag="VVR21_001619"
     CDS             14295..15962
                     /gene="recN"
                     /locus_tag="VVR21_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU6055442.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            15964..16692
                     /locus_tag="VVR21_001620"
     CDS             15964..16692
                     /locus_tag="VVR21_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU6055443.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            16771..18594
                     /gene="lepA"
                     /locus_tag="VVR21_001621"
     CDS             16771..18594
                     /gene="lepA"
                     /locus_tag="VVR21_001621"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU6055444.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(18675..>18969)
                     /locus_tag="VVR21_001622"
     CDS             complement(18675..>18969)
                     /locus_tag="VVR21_001622"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055445.1"
                     /translation="YSKHSFEVVDKTDEVSSKHGFEVVDETDEVSSKHGFEVVDETDE
                     VSSKHDFEVVDETDEVSSKHGFEIVDETDEVSNHTYGKATLTWFEEIFEEYKN"
BASE COUNT         5660 a         3441 c         4427 g         5441 t
ORIGIN      
        1 aaatctgaac aaatcaatta ggaatttaaa gcattttata acaacgtttt agagtgatgg
       61 ggtgctattt caacttcaac ctactataat acagaaaaaa acaactccct gatgattcaa
      121 ggagttgtct atagttaaat tagtttttag aagcttcttg gaattctgga tttttccatg
      181 cttcgtcaat aatagcttgc aattctttag cagatgcttg cattttttga gtttctgcat
      241 cgttcaatgg aatgtttact ggacgaatga taccatgtgc accaacaaca gctggttgac
      301 cgataaagac attctcaact ccgtattgac cttcttggaa tactgaaagt ggaagtactg
      361 cgttttcatc gtcaaggatt gctttagtga tacgagcaag ggctactgcg ataccgtagt
      421 atgttgcacc ttttttgttg atgattgtgt aggctgcatc acgaacacct tcgaacaatt
      481 caatcaattc agcttcttga acattttgag tgtctttaag gaattcttca aggtttacac
      541 cagcgatgtt agcgtgtgac caaacagcga actcagagtc accgtgttca cccatgatgt
      601 aggcgtgcac tgaacgagca tccacatcca atttttcagc aagtgcttga cggaaacgag
      661 ctgagtcaag tgaagtacct gaaccgataa cgcgttcttt agggaaacca gagaatttcc
      721 aagttgagta agtcaaaacg tcaactgggt tagcagcaac aaggaagata cctttgaaac
      781 cagattcaac aacttgagtt acgattgatt tgttgatagc aaggttttta cctacaaggt
      841 caagacgagt ttcacctggt ttttgaggtg cacctgcagt gatcacaaca aggtcagcgt
      901 ctgcacagtc agagtattga gctgcataga tttttttagg tgaagtgaag gcaagggcgt
      961 gactaaggtc aagcgcatca ccaacagctt tttcatgcaa ttgtggaatt tcgataattc
     1021 caagctcttg tgcaattcct tggttaacaa gtgcaaaagc gtaagatgaa cctacagcac
     1081 catcaccgac aaggataact tttttgtgtt gtttagttga agtcattgtt ttaaacatct
     1141 ccttaatttt attaggggat tttccctaga caacttcatt ctatcacttt taaaaaactt
     1201 tgtcacgaat atgccttata gttctcgatg taaacgtttt agtggtttag aggctgaaat
     1261 agatgggaat ttatggtata atgttgttac ttactaattg tgaaatgagg catttattaa
     1321 tgcaggataa aaatttagtg aatgtcaatc tgacaaagga gatgaaggca agttttatcg
     1381 actacgccat gagtgttatc gtagcgcgag ctcttcctga tgttcgagat ggcttaaaac
     1441 ctgttcaccg tcgcattctc tacggaatga atgaattggg tgtgacccca gacaaacccc
     1501 ataaaaaatc tgctcgtatt acaggggatg tcatgggtaa atatcaccca cacggggatt
     1561 cctctattta tgaagccatg gtccgtatgg ctcaatggtg gagctaccgt tacatgcttg
     1621 tagatggtca tgggaatttt ggttccatgg atggagatag tgctgccgct caacgttata
     1681 ccgaggcacg tatgagcaag attgctctgg aaatgcttcg tgatatcaac aaaaatacag
     1741 ttgatttcgt tgataactat gatgccaatg aacgggaacc cttggtcttg ccagcgcgtt
     1801 ttccaaacct tttggttaat ggagcaactg gtatcgcggt tgggatggca accaatattc
     1861 cacctcataa tctgggtgaa accattgatg cagtgaagtt ggtcatggat aatcctgaag
     1921 tgactaccaa ggacttgatg gaagtcttgc ctggaccaga ttttccaact ggtgctcttg
     1981 tcatggggaa atcaggtatc cataaggctt atgaaacagg taaaggttcg attgtcctac
     2041 gttctcgtac agagattgaa acgactaaga ctggtcgtga gcgcatcgtt gtaacagaat
     2101 ttccttacat ggtcaataaa accaaggtgc atgagcatat tgttcgcttg gttcaggaaa
     2161 aacgcattga gggtatcaca gcagtacgtg atgagtcaaa ccgtgaaggt gttcgatttg
     2221 ttattgaagt caagcgcgac gcctcagcca atgttattct caataacctc ttcaaaatga
     2281 cccaaatgca aaccaatttt ggtttcaata tgctcgctat ccaaaatggt ataccgaaaa
     2341 ttttgtctct tcgtcagatt ttggatgctt atatcgagca ccaaaaagaa gtggttgttc
     2401 gtcgtacacg ttttgataag gaaaaagcgg aagcgcgcgc tcatatctta gaaggtctct
     2461 tgattgcgct agaccatatc gacgaagtga ttcgtatcat ccgtgctagt gaaacggatg
     2521 cggaagctca agctgagttg atgagcaagt ttaagctttc tgaacgtcaa agtcaagcta
     2581 tccttgatat gcgtcttcgt cgtttgacag gtttggaacg cgataagatt caatctgagt
     2641 atgatgacct cttggctctg attgcggatt tagcagatat tcttgctaag cctgaacgtg
     2701 tttctcaaat tatcaaagac gaattggatg aagttaaacg taaattttct gataaacgcc
     2761 gtacagagtt gatggttgga cagatcttga gtctcgagga tgaggacttg attgaagaat
     2821 cggatgtctt gattaccctt tctaacagag gctacattaa gcgtttggat caggacgagt
     2881 tcactgctca aaaacgtggg ggtcgtggtg tccaaggaac gggagtgaaa gatgatgact
     2941 ttgttcgtga gttagtgtca actagcacac atgatcatct gctcttcttc acaaacaagg
     3001 gacgtgtcta tcgtcttaaa ggttatgaaa ttcctgagta tggtcggact gccaaagggc
     3061 taccagtagt caatctcttg aaattggatg aagacgaaag tattcagacg gttatcaatg
     3121 ttgagtctga tcgcagtgat gatgcttatc tcttctttac aacccgtcac ggtattgtga
     3181 agagaactag tgttaaggag tttgccaata ttcgtcaaaa tggtctcaaa gcgctgaatt
     3241 taaaggatga agatgagtta atcaatgtct tgttggcaga aggagatatg gatattatca
     3301 ttggtaccaa gtttggttat gcagttcgct ttaatcaatc agccgttcgt ggtatgagcc
     3361 gtatcgccac tggtgtgaaa ggtgttaacc ttcgtgaagg agacacagtt gttggtgcca
     3421 gcttgattac tgatcaagat gaggttctta ttatcacaga aaaaggatat ggtaagcgta
     3481 cagtcgctac tgaataccca acaaaaggtc gtggtggtaa gggaatgcag acagctaaaa
     3541 ttaccgaaaa aaatggcttg ctggccggtc ttatgactgt tcaaggggat gaggatttga
     3601 tgattatcac tgatacaggt gtcatgattc gaaccaatct tgccaatatt tcacaaacag
     3661 gacgtgcaac tatgggagtt aaagtaatgc gcctggatca agatgctcag atagtgactt
     3721 tcacaacggt tgcggtggca gaaaaagaag aagttgggac agaaaacgaa acagaaggtg
     3781 aagcataatg tctcaaaaaa ataataaaaa gaaaaacaag cgaaaaaatc tgctgacaaa
     3841 tatcctagca ggatttctga tattactgtc actggctttg atttttaata ctcaaattcg
     3901 aaatattttc atagtctgga ataccaataa gtatcaagtt agccaggtat caaaagaaaa
     3961 attagaagaa aatcaggata cagaaggcaa ttttgacttt gattctgtca aagctatctc
     4021 ttcggaagct gttctaactt ctcaatggga tgctcaaaaa ttaccagtta ttgggggaat
     4081 tgcaattcct gaattggaaa tgaatttgcc gatttttaaa ggacttgata atgttaatct
     4141 cttctacgga gctggtacaa tgaaacgcga gcaagtaatg ggagaaggaa attatagtct
     4201 agctagtcac catatctttg gtgttgataa tgctaataaa atgttatttt ctcctttaga
     4261 taatgctaaa aatggcatga agatttatct aaccgataaa aataaagttt atacttatga
     4321 aatacgtgaa gtcaaacgtg tgacaccgga tcgtgttgat gaagttgatg atagagatgg
     4381 ggtcaatgaa atcacattag taacctgtga agaccttgct gctacagaac gtattattgt
     4441 caaaggtgat ttgaaagaaa caaaagatta ttcacaaaca tctgatgaaa tcctaacagc
     4501 tttcaatcaa ccatataaac aattttatta atacaaatca gtgaaatcat ggatttcact
     4561 gattttttaa gattttcata aaaatatagt aaaatgaaat aagaatagga cgaatcgttc
     4621 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
     4681 aatctactat aaacttttat gaaatacaga aaacgcttcc taaaacctaa agtttgtgat
     4741 ataattatca agaaaaaaga tttaggagtt tattatggtt tcttcagaat ttatttcaaa
     4801 gattgaattt gcttgcaata agaaagaaag tctttatagt caaagcaaat ttaagtatgc
     4861 gattcgttcg atattcgcag gtgcattttt aaccttcagt actgctgcag gtgcagttgg
     4921 ggctgacttg attaataaaa ttgcaccagg tagtggacgc ttcctctttc cattcgtttt
     4981 tgcttggggc ttggcctaca ttgttttttt gaatgccgag ttggtcactt caaacatgat
     5041 gttcttgact gctggtagtt tcttaaaaaa aatctcttgg agaaaaacag ctgagatttt
     5101 actatactgt accttgttca accttatcgg agccttgata gcagggtggg gctttgctca
     5161 ttcggcagcc tatgcgaatc tgatacacga tagtttcatc tcaggtgttg ttgagatgaa
     5221 gttaggccgc tcaaatgaat tggtcttgct tgaggcgatt ttggcaaata ttttcgtaaa
     5281 tattgcgatt ctgtcattta ttttggtcaa agatggtggt gccaaacttt ggcttgtgtt
     5341 gtcagctatt tacatgtttg tattcttaac aaacgagcac attgcggcga actttgcttc
     5401 tttcgcgatt gtgaaattca gtgttgctgc ggattcaatt gccaacttcg gtgttggaaa
     5461 tatgcttcgc cactggggtg tgactttcat cggaaacttt atcggaggag gcctcttgat
     5521 gggtcttcca tatgccttcc tcaataaaaa cgaagatact tatgtagatt aagaaaatga
     5581 gcacgattga gtcgtgcttt tttcattttc aaaataaggt aatagctatt tcttatatca
     5641 aaatatagaa aactgatatt tgtaaactat aactcaaggt gctacaatat ccttaataaa
     5701 atgatatgga ggtcacctta tgacttgtga ttttaaattt gaaactctac aactacatgc
     5761 tggtcaagtt gtggctccag ctactaagtc tcgtgcagtg ccgatttatc aaacaacatc
     5821 ttttattttt gatgacacgt aggaaggtgc tgatctgttt gccttgagga aaccagggaa
     5881 catttatact cgtatcacca atcctacaac agctgccctt gaaggtggtg ttgaagcgct
     5941 agcaacagca tcaggtatga ctgcagtgac ttatacgatt ttggcgcttg cccatgctgg
     6001 tgaccatgta gtggctgctt cgactattta cggtggaacc ttcaatcttt tgaaagaacc
     6061 ccttcctcgt tatggtatca caacaacctt tgtcgatgtt gataatttgg aggaagtaga
     6121 agcagctatc aaagacaata ccaagcttgt cttgattgaa accttgggta actccttgat
     6181 taatattcca gacctggaaa aactggcaga gattgctcat aaacatcaaa tcccacttgt
     6241 gtcagacaat acttttgcaa taccttattt gattaacgtc ttctctcatg gcgttgacat
     6301 tgccattcac tctgcgacta agtttatcgg tgggcatggt acaactattg gaggaataat
     6361 tgtcgatagt ggtcgttttg actggacggc ttcagggaaa ttccctcaat ttgttgacga
     6421 gggtccaagc tgccacaatt tgagttatac ttgtgatgtg ggtgcagcag cctttattat
     6481 agctgttcga gttcaattgc ttcgtgatac aggtgcagcc ttgtcaccat tcaatgcttt
     6541 cctcttgcta caaagacttg aaacctcttc acttcgtgtg gaacgccatg tacaaaatgc
     6601 tgagacaatt gttgattttc ttgtcaacca tcctaaggta gaaaaggtaa attatccaaa
     6661 acttgcagat agtccttatc atgccttggc tgagaaatac ttgccaaaag atgtcggttc
     6721 aatctttacc ttccatgtca aaggtggcga ggaagaagca cgcaaggtca ttgataattt
     6781 agaaatcttt tctgatcttg caaacgcggc agatgctaaa tcgcttgttg tccatccagc
     6841 aacaaccact cacggtcaat tgtcagaaaa agacctagaa gcagcaggtg tcacaccaaa
     6901 ctaaattcgt ttgtcaatcg gtcttgaaaa tgtagaagat ttgattgaag acttgcgctt
     6961 ggccttggaa aaaatttaaa gtaaaagaag ataaacagtg ggcttcgact cactgttttt
     7021 gattttccct caggcatgat ataatggtta aagaagtcta gaaagaggaa cgatatgaac
     7081 gaaatcaaat gtcccaactg tggggaagtc tttacagtaa atgagagtca gtatgccgaa
     7141 ctcttgtccc aagtgagaac ggcagagttt gataaggaac tacacgatag gatgaagcag
     7201 gaactggcct tggctgagca aaaggccatg aatgagcaac agactaaact ggctcagaag
     7261 gatcaagaaa ttgcgcaatt acagagtcag atccaaaact ttgatacaga aaaagaattg
     7321 gccaagaaag aggttgaaca gacaagccat gaggctctct tggctaagga caaggaagta
     7381 cagctcttag aaaatcagtt ggctaccttg cgtttggagc atgaaaatca actgcaaaag
     7441 accctttctg acctagaaaa agaacgggat caggttaaaa accaactact tttgcaggaa
     7501 aaggaaaatg aattatcttt ggcttctgtt aagcaaaact acgaagccca gctcaaggca
     7561 gctagtgaac aagtcgagtt ttataaggat tttaaggctc aacaatctac aaaagcgatt
     7621 ggggaaagcc tagaacagta tgcagagagt gagtttaaca aggttcgtag tttcgccttt
     7681 ccaaatgctt actttgagaa ggataacaag gtctcttcgc gtgggtctaa aggggacttt
     7741 atcttccgtg agtgtgatga aaatggagtt gaaatcattt ctatcatgtt tgagatgaaa
     7801 aacgaagcag acggaacaga gaagaagcac aagaatgcag atttttacaa ggaattggac
     7861 aaggaccgtc gggagaagaa ctgtgagtat gccgttttgg tgaccatgct tgaggccgat
     7921 aatgactact ttaacacagg gattgttgac gtcagacacg agtatgaaaa aatgtatgtt
     7981 gttcgtcctc aattctttat ccaattgatt ggtctcttac gtaatgcggc gctaaattcc
     8041 ctaaaataca agcaggagtt ggccttggtt cgcgagcaaa atattgacat tacgcatttt
     8101 gaggaagatt tggatgcctt taagctagct tttgctaaga actataattc agcttcgact
     8161 aactttggaa aagctattga tgaaatcgac aaggccatca aacgcatgga agaggttaag
     8221 aaattcctga ctacatctga aaaccaactc cgtctagcta acaacaaatt ggaagatgtc
     8281 tctgttaaaa aattgacccg gaaaaatcca acaatgaaag cgaagttcga agcactgaag
     8341 ggggagtaga aagcaaaaat gaacggtatt atcaacttaa aaaaagaagc aggaatgacc
     8401 tcgcatgatg cggtttttaa actgcgtaag attttgggaa ccaagaaaat tggtcatggc
     8461 ggaaccttgg atccggatgt ggtgggtgtt ttgccgattg cggttggcaa ggcgacacgc
     8521 atggtcgagt ttatgcagga cgagggtaag atctatgagg gggaaatcac tctgggctat
     8581 tccacgacga ctgaggatgc tagtggggaa gtggtcgcag aaacccctgt tttgtctccc
     8641 ttggatgaaa agcttgttga tgaagcgatt gctagcttga ctgggcctat tacccagatt
     8701 ccccctatgt attcggcagt taaggttaat ggtcgcaagc tctatgagta tgcgcgtgct
     8761 ggtcaggaag tggagcgttc agaacgtcag gtgaccattt atcaatttga gcgaacaagt
     8821 ccgatttctt atgatggcca acttgcccga ttcacttttc gtgtaaaatg cagtaaaggg
     8881 acttacatcc gtactttgtc agttgatttg ggtgaaaagc ttggttatgc ggctcatatg
     8941 tcccatttga ctcgtactag tgctgctggc ttacaattag aagatgctct taccttggag
     9001 gaaattgctg aaaaagtaga ggctgggcaa ttagattttc tccatccttt agagattggg
     9061 acaggtgacc ttgtcaaagt tttcctaact ccagaagatg ctacagaagt tcgctttggt
     9121 cgttttattg agctagacca aacggacaaa gaactggctg cctttgaaga tgataaattg
     9181 ttagccattc tagaaaaacg gggcaatctc tataagccaa ggaaggtttt tagctagatc
     9241 gtttaggaat aaaaatcggg tgatagataa caattgcttg ataaaacccc atactaatag
     9301 tagaatggtt ttgggaatta taatattcca attgttgcga gttgtagata ctcaaataat
     9361 ctatatagaa atttagaggt gtgaaatgaa gcaacttaaa attctttcag ataaatattt
     9421 agagtccatt acaggttctg gtgggaactt aggcccagga tttggtgtga taattccatg
     9481 atgcgaaatg agtttcgaga aagggtggag caacttcttc aacaaaaaga aataaatgaa
     9541 aatagtgagt tgagtcacct gtttcgtctt gctatacaaa atttagacag aaatgaaaaa
     9601 taccaaacgg tcatggccaa tttgagtcaa gggttgtcac tttacctcat gacgcatcat
     9661 taccaggcac ctaagtctgt cattgatttt ggtttatgga ttgccaaagc tcctagccag
     9721 gaaagaggga gactggcttt cttgcagatg cttgctcaaa ccctacaggg ctttcgttaa
     9781 aactgtcgaa catcagaggg aagactctgg tgttttttgc tgatgagact ataaattttg
     9841 taaaaaatgt gatagaatag acgacggata aaataacgga ggatagcatg caaaatagac
     9901 caatcattat tggagtgaca ggtggttctg gtggtggtaa aaccagtgtt tcaagagcca
     9961 ttttatcgca ttttcctgat gaaaagattt ccatgattga gcatgattca tactacaagg
    10021 atcagtctca tttgaccttt gaagagcgtg tcaaaaccaa ctatgaccat ccttttgcct
    10081 ttgatacaga cttgatgatc gagcagatta aggaattgtt ggcagggcgt ccggtggaca
    10141 tcccgaccta cgactataca gagcatacac ggagtagcaa gacctatcgt caggagcctc
    10201 aagatgtctt tatcgttgag ggcattttgg tcttggagga caagcgtctg cgcgatttga
    10261 tggatatcaa gatttttgtg gatacggatg acgatgtgcg cattattcgt cgtatcaagc
    10321 gtgatatgga ggagcgtggc cgtagccttg atagcgttat taaccagtac ttaggtgtgg
    10381 tcaaaccaat gtaccaccag tttatcgagt caactaagcg ttatgctgat atcgtcattc
    10441 ctgaaggggt tagcaatacc gtggctatcg acctgttgac gaccaagatt gcaaagattt
    10501 tggaagaagc tcgaaacagc aaataatcac atgtggaggc cttgcctcct ttttctattt
    10561 ttccctcata atggtacata aatggagatt tttaggcata tttttggtat aataataccc
    10621 atgaaagagc aagtaaatga atagtaggtg gagatggaaa agtatttatc ggtaacaact
    10681 ttgaccaagt atctgaaaat gaaattcgat aaagacccat acttggaacg ggtctattta
    10741 actggtcaag tttccaactt tcgtaaacga cctactcacc aatatttctc cctaaaggat
    10801 gaccatgcag ttattcaagc gaccatctgg tctgggattt atcagaaatt agggtttgac
    10861 ctggaagaag gaatgaagat caatgtgatt gggcgtgtac aggtttatga accaagtggt
    10921 agctactcca tcatcattga aaaagctgag cctgatgggg ttggggcgct tgcgattcag
    10981 tttgaacaac ttaagaaaaa attgacagaa gaaggcctgt ttcaagaacg cttcaagcaa
    11041 gctctgcccc aattttctaa gagaattggg gtagtaacca gccgtagtgg agccgttatt
    11101 cgagatatta tcacgaccgt cagcaggcga ttcccaggtg ttgacatcct tctttatccg
    11161 accaaggttc aaggtgaagg ggctgcggag gaaattgcta gaaatattgc gcgtgctaat
    11221 caacgggacg atttggattt gctcattatt ggtcgtggag gtggttctat tgaggatctc
    11281 tgggccttta acgaagaaat tgtggtacga gctatttttg aatctcgttt gccagttatc
    11341 tctagtgtgg ggcatgagac ggatgtgacc ttggcagatt ttgtggcaga tcgacgcgct
    11401 gcaacgccaa cagcggcggc tgaactggca acacctgtga ccaagttgga tgtattagct
    11461 catttgcaaa atcaggaaaa acggatggta acggcagtcc gaaatgttct atctaagaaa
    11521 caagaggctt tgaaaaaatg cagtcagtct gttatcttta gacaacctga gcgcttgtat
    11581 gacggttatt tgcaacgctt ggaccaactg caactgcgtt tgaaacaaag tttgcgaact
    11641 cggatttctg ataacaaaca attagttcaa gcaagaactc atcaattagt acaattatca
    11701 cctgttacca aaatccaacg ctatcaagac cgtttaggac agttggacaa gctcttaggt
    11761 agccaaatgg cgttagttta tgacgccaag gttgctgagg tcaagcgact ttcggaagct
    11821 ttgctcatgt tggatactag ccgaatcgtg gcgcgtggtt atgctattgt caaaaaagaa
    11881 gagtccgttg tagattcggt tgagagtttg aagaaaaaag accaagtaac gcttttgatg
    11941 cgagatggtc aagtagaatt agaggttaaa gatgtcaaaa caaaagaaat ttgaggaaaa
    12001 tctagcagaa ctggaaacca ttgtccaaag tttggaaaat ggtgaaattg ctctggaaga
    12061 tgcgattact gcctttcaaa agggcatggt cttgtcaaaa gagctccaag ctacgctgga
    12121 caaggctgaa aagaccttgg tcaaggtcat gcaagaagac ggaacagaaa gtgattttga
    12181 atgaaaaagc aagaaaaatt agctcttgtc gagtcggctt tggaagattt ttatggagac
    12241 cagcagtttg cctctagttt acgggagtct gttctctatt ctattcatgc tggtggcaag
    12301 cgtattcggc cttttctctt gttagaagtt ctggaagcct tgcaggttac catcaaacct
    12361 gctcacgcgc aggtagctac tgccttggag atgattcata cagggagctt gattcacgat
    12421 gaccttcctg ctatggatga tgacgattat cgaagagggc ggttaaccaa tcacaagaaa
    12481 ttcggtgaag ctatggccat tttggctgga gatgccttat tcttagactc atatgccttg
    12541 attgcgcagg cagatttgcc aagtcagatt aaggtggact tgattgccaa cttatccctt
    12601 gcttcaggta gtctgggtat ggtggcaggg caagttttgg atatggaggg cgaacaccag
    12661 cacttgtctt tggaagaact tcagactatt catgccaata agactgggaa gttactagcc
    12721 tatcccttcc aagcggcagc tattatagct gaattgtcac ctgaaatgca ggtgaagctg
    12781 aaaactgtgg gtgaattgat tggacttgct tttcaagtca gagatgatgt actggatgtg
    12841 acagctagtt ttgaggaaat cggcaagaca cctcaaaagg atctgcaggc agaaaaatca
    12901 acctatcctg ccctgttggg cttggaagag tccattgcct tttgtaacca aaccctggat
    12961 caagctaatg aaaaattaga agaaattgcc cagcagattc cctttgaaac agaatcgatt
    13021 gtaagtgtag tagaaagttt gagaatcaat ggctaaggaa agagtggatg tactagctta
    13081 taaacagggg ttgtttgaaa cgagagagca ggccaagcga ggtgtgatgg ctggcctagt
    13141 cgtagcagtc cttaatggag aacggtttga caagccagga gagaaaattc cagatgacac
    13201 cgaattaaaa ctcaaggggg agaaactcaa gtatgtcagc cgtggtggtt tgaaactgga
    13261 aaaggccttg caggtctttg atttgtcggt ggatggcgcg actacgattg atatcggggc
    13321 ctctactgga ggttttaccg atgtcatgct acagaatagt gccaagttgg tctttgcagt
    13381 cgatgttggt accaatcagt tggcttggaa attacgccaa gacccacgag ttgtcagcat
    13441 ggagcagttc aatttccgct atgctgaaaa gactgatttc gagcaggagc cgagctttgc
    13501 cagtattgat gtgagtttca tttcccttag tctgattttg ccagccttgc accgtgtctt
    13561 ggctgatcaa ggtcaggtgg tagcacttgt caaacctcag tttgaggcag gacgtgagca
    13621 gattgggaaa aatggaatta ttcgagatgc taaggttcat cagaatgtcc ttgaatctgt
    13681 aacagctatg gcagtagagg caggtttttc agtccttggc ttggactttt ctcccatcca
    13741 aggtggacat ggaaatattg aatttttagc gtatttgaaa aaagaaaagt cagcaagcaa
    13801 tcagattctt gctgagatta aagaagcagt agagagggcg catagtcaat ttaaaaatga
    13861 ataaaaaaga aagacttgaa aaaattagaa gattggtgac agattatcaa atcggcacgc
    13921 aagaagaaat tgtagaacat ttgaaagaag caggtatcac tgccactcag gcgacggtat
    13981 cccgagatat caaagagtta ggtattgtca aaattccttt gagagacaac acctatgtct
    14041 acgaattgcc aaaatcaatc gtaaaaagtc tgcaactggc tgaagacaat atcgaatcgg
    14101 ctgaattgat ggataagatg atcaatctcc aagttattcc aggaaatacg gcttttgtaa
    14161 aagctcagtt aatcgagact tttgcagaca agatttttag ctgtttgact gatgatagct
    14221 cgattttagt cattgccaga agtggaagtc tagcagagga aatctttgaa caagtaaaaa
    14281 attggtaggt ctatatgtta cttgaaattt cgataaaaaa ctttgccatt attgaggcta
    14341 tttccctcaa ttttgaaaag gggatgactg tcctgactgg tgaaacgggt gcagggaagt
    14401 cgattatcat tgatgccatg aatatgatgt tgggagctcg tgcgacgaca gatgttattc
    14461 gtcatggtgc accaaaggca gagattgagg ggcttttctc agttgagaat agtcgtcttt
    14521 tacaggaaat ttttgatgag caaggtttag aattaggtga tgaaattatc atccgtcggg
    14581 aaatcttgca aaatggtcgt agtatcagcc gtgtaaatgg tcagatggtt aatctgtctg
    14641 ttttgcgaac tattgggcaa catcttgtag atattcatgg tcagcatgac catgaggagt
    14701 taatgcgtcc ccaactgcat atccagatgt tggatgaatt tggtgatgcc gctttttggg
    14761 acttgaaaga aacctatcaa acgagttttg atgcctatcg gaaaatgcgc aagcaggttc
    14821 tggaagtcaa gaaaaaccaa caggaacaca aggcacgtat cgaaatgttg gaatttcaaa
    14881 tggcagagat tgaggcagca aacttgcagg ctggagaaga cttggatctc aatcaagagc
    14941 gagataaact cctcaaccac aaaaatattg cggatacact gaccaatgcc tacagtatgt
    15001 tggacaatga agatttttca agtctggcca atgttcgttc agccatgaat gacatggaaa
    15061 gtgtcgaaga gtatgaccct gaataccgtg aaatttcaag ctctctgtct gagacctact
    15121 atgttttaga agacattagc aaacgtttgg aagctatcat tgaggacctt gattttgatg
    15181 gcaatcgcct catgcaggtt gagaatcgtt tggacctcct tcatactatt actcgtaagt
    15241 atggtgggac tgttgatgat gttttgcttt attttgccaa gattacggaa gaatacaatc
    15301 tcttgacagg caataatctt tcgtctgagg acatggaagc agagcttaag aagttggaag
    15361 tcaatcttgt caatttggca ggtcaacttg cttctgctcg tcataatttg gctcagcaac
    15421 tcgaagctga gattaaacaa gaactgcaag atctttatat ggaaaaagcc cagtttcagg
    15481 ttcgttttag taagggaaaa ttcagtcgtg agggaaataa aatggttgag ttttatattt
    15541 caaccaaccc tggagaagac tttaaaccct tggttaaggt tgcttctgga ggggaattat
    15601 ctcgtctcat gttagccatt aagtctgcct tttcacgtaa agaaggcaag actagcattg
    15661 tctttgatga ggtggatacg ggagtttcag gtcgtgttgc tcaagctatt gctcagaaaa
    15721 ttcataaaat tggtcagcat ggtcaggttt tggctatctc ccatttgcca caagtaattg
    15781 cgattgcaga ttatcaattc tttattgaga agattagtaa tgaccattca acggtttcga
    15841 ctgttcgtct cttgacggtc gaagagcgag tggaggaagt tgccaagatg ttggcaggtg
    15901 atgatgtgac agaagcagcc ctgacgcaag ccagagaatt gttgagaaac agggagaaat
    15961 aagatgacag attattatgt aattggagat gttcacggaa aagctgggat gctggaagac
    16021 cttcttaaaa cctgggatgg tcagacccag ttgctctttc taggtgattt gattgacaga
    16081 ggtgaggata gtcaccgtgt tcttgaaatg gtcaaggact tggtggacaa tcaaggggct
    16141 atctgtttgt ccggaaacca cgagtatatg tttttgactt ggctagatga cccagaagaa
    16201 agttatgacc attatcgtcg caatggtgga gatacaacca ttaactctat cctaggtcgt
    16261 cccttggatg caccagttga tggagtagaa gatgccaagc gggttgccgc tgaagcggca
    16321 gacttggtcg aattcattcg tcaaatgcca tttgtagtag agacagacaa gtatatcttt
    16381 gttcacgcag gtattgattt gaccttggac gactggcatg aaacaacaga ttataaaaaa
    16441 gtatggctta gaaaaccatt ccacggagct gaaaatcata ctggaaaaac cattgtcttc
    16501 ggtcatacac cggtctatgg tttgttacag caagaacgcg gtacatctga gctttggact
    16561 acagaagatg gcaagattgg aatggatgga ggagctgttt atggtggtgt ccttcacggg
    16621 attgtcttta cagaccaagg aatgacagaa caccacttta tcgaaaatga cggctttgtc
    16681 gctgaagatt agtactccta gcagggtatg gtcttgtcaa aatatcaaaa acaatttata
    16741 ataaatagat accctgaaag gaagagaatc atgaacttag aagaattgaa aaaacgacag
    16801 gagaagatcc gtaacttctc tattatcgcc catattgacc acggaaaatc aactctagca
    16861 gaccgcattt tggaaaaaac agagacggtt tcaagtcgtg aaatgcaggc ccagcttttg
    16921 gatagcatgg atctagagcg ggaacgtgga attactatta agttgaatgc catcgagttg
    16981 aattacactg caaaagatgg ggaaacttat attttccact tgattgacac accagggcac
    17041 gttgacttta cctatgaagt ttcacgttcg ctagctgcct gtgagggtgc tattttggtg
    17101 gtcgatgcgg ctcaaggaat tgaggctcaa actcttgcca acgtttatct ggctttggat
    17161 aatgatttgg aaatcatgcc tatcattaat aaaattgacc tgccggctgc agatccggag
    17221 cgcgtgcgta cagagattga agatgtgatt ggtttggatg ccagtgaagc agttttggct
    17281 tctgccaagg ctggtattgg gattgaagaa atcctcgagc aaattgtaga aaaagtacca
    17341 gcaccaacgg gtgatgtgac ggcgccactt aaggccttga ttttcgactc tgtttacgat
    17401 gcttaccgtg gggttatcct ccaagtgcgt gtcatggacg gagtggtcaa acctggtgat
    17461 aagattcagc tcatgagcaa tagtaagacc tttgatgtgg ccgaagtcgg tatttttaca
    17521 ccaaaagcgg ttggtcgtga tttccttgcg actggtgatg ttggttacat tgcggcgtct
    17581 atcaagacgg ttcaggatac tcgtgtgggt gataccgtta ccttggcaac caatcctgcg
    17641 gcagaaccat tacatggtta taagcagatg aatcctatgg tctttgcggg tctctaccca
    17701 atcgaatcaa acaagtacaa tgacctgcgt gaagcgcttg aaaaattgca actgaatgat
    17761 gctagtcttc agtttgaacc agaaacatct caggcacttg gatttggttt ccgttgtgga
    17821 tttcttggac ttctccatat ggatgttatt caggaacgtt tagagcgtga gttcaatatt
    17881 gacctcatca tgacagctcc gtctgttatt tacaaagtta atttgaccga cggtgagtct
    17941 atggatgtgt ctaacccatc tgagtttcca gacccaacta agattgcgac cattgaagag
    18001 ccttatgtca aggcgcaaat catggtacca caggagttcg tcggagcagt aatggagcta
    18061 gctcagcgta agcgtgggga ctttgtgact atggactata ttgatgataa ccgtgtcaat
    18121 gttatctatc aaattcctct tgctgaaatt gtctttgact tctttgataa acttaagtct
    18181 tcgacacgtg gttatgcaag ctttgactac gaattgtcag aatatcgccc atctaagctg
    18241 gtgaaaatgg atatccttct caatggagat aaggtggatg ccctcagctt tatcgttcac
    18301 aaggactttg cctacgaacg tgggaaactc atcgttgata aactcaagaa aatcatccct
    18361 cgccaacaat ttgaagttcc aatccaagcg gctattggac acaagattgt cgctcgtact
    18421 gatatcaagg cccttcgtaa gaacgtactt gctaaatgtt atggtggtga cgtttctcgt
    18481 aagcgtaaac tccttgaaaa acaaaaagct ggtaagaaac gcatgaaatc catcggatca
    18541 gttgaagttc cgcaagaagc cttcctcagc gtcttgagta tggatgaaga ataagttatc
    18601 agaaatgcct ttccttgttc acaggaaatt tatataagaa tcaatagtaa tgcaggctta
    18661 gatggtctgc ttttttagtt tttatactct tcgaaaatct cttcaaacca cgtcagcgtc
    18721 gccttaccgt atgtatggtt actgacttcg tcagtttcat ctacaatctc aaaaccatgt
    18781 tttgagctga cttcgtcagt ttcatctaca acctcaaaat catgttttga gctgacttcg
    18841 tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt ttcatctaca
    18901 acctcaaaac catgttttga gctgacttcg tcagtcttat ctacaacctc aaaactgtgt
    18961 tttgagtaa
//
LOCUS       DAVHSI010000038        18693 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.038, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000038 DAVHSI010000000
VERSION     DAVHSI010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.038"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            49..507
                     /locus_tag="VVR21_001623"
     CDS             49..507
                     /locus_tag="VVR21_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU6055446.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            520..1128
                     /locus_tag="VVR21_001624"
     CDS             520..1128
                     /locus_tag="VVR21_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055447.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1199..1531
                     /locus_tag="VVR21_001625"
     CDS             1199..1531
                     /locus_tag="VVR21_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055448.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1542..2957
                     /gene="ply"
                     /locus_tag="VVR21_001626"
     CDS             1542..2957
                     /gene="ply"
                     /locus_tag="VVR21_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU6055449.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            3838..4554
                     /locus_tag="VVR21_001627"
     CDS             3838..4554
                     /locus_tag="VVR21_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6055450.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            4678..5127
                     /locus_tag="VVR21_001628"
                     /pseudo
     CDS             4678..5127
                     /locus_tag="VVR21_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            5166..5987
                     /locus_tag="VVR21_001629"
     CDS             5166..5987
                     /locus_tag="VVR21_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055451.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVVVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM"
     gene            5994..7025
                     /locus_tag="VVR21_001630"
     CDS             5994..7025
                     /locus_tag="VVR21_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6055452.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARTLLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            7091..7453
                     /locus_tag="VVR21_001631"
     CDS             7091..7453
                     /locus_tag="VVR21_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU6055453.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7450..7953
                     /locus_tag="VVR21_001632"
     CDS             7450..7953
                     /locus_tag="VVR21_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU6055454.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWNTCPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLNFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8067..8513
                     /locus_tag="VVR21_001633"
     CDS             8067..8513
                     /locus_tag="VVR21_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055455.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8518..9192
                     /locus_tag="VVR21_001634"
     CDS             8518..9192
                     /locus_tag="VVR21_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055456.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            9353..9544
                     /locus_tag="VVR21_001635"
     CDS             9353..9544
                     /locus_tag="VVR21_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU6055457.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            9829..10128
                     /locus_tag="VVR21_001636"
     CDS             9829..10128
                     /locus_tag="VVR21_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU6055458.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10125..10442
                     /locus_tag="VVR21_001637"
     CDS             10125..10442
                     /locus_tag="VVR21_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU6055459.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            10458..11084
                     /locus_tag="VVR21_001638"
     CDS             10458..11084
                     /locus_tag="VVR21_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU6055460.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11117..11878
                     /locus_tag="VVR21_001639"
     CDS             11117..11878
                     /locus_tag="VVR21_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU6055461.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGDDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTHCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            11956..12351
                     /locus_tag="VVR21_001640"
     CDS             11956..12351
                     /locus_tag="VVR21_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU6055462.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            12621..12905
                     /gene="groES"
                     /locus_tag="VVR21_001641"
     CDS             12621..12905
                     /gene="groES"
                     /locus_tag="VVR21_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU6055463.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            12921..14543
                     /gene="groL"
                     /locus_tag="VVR21_001642"
     CDS             12921..14543
                     /gene="groL"
                     /locus_tag="VVR21_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU6055464.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            14681..15436
                     /locus_tag="VVR21_001643"
                     /pseudo
     CDS             14681..15436
                     /locus_tag="VVR21_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(15876..16409)
                     /locus_tag="VVR21_001644"
     CDS             complement(15876..16409)
                     /locus_tag="VVR21_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU6055465.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(16498..17274)
                     /gene="recX"
                     /locus_tag="VVR21_001645"
     CDS             complement(16498..17274)
                     /gene="recX"
                     /locus_tag="VVR21_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU6055466.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVEQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            17312..18667
                     /gene="rlmD"
                     /locus_tag="VVR21_001646"
     CDS             17312..18667
                     /gene="rlmD"
                     /locus_tag="VVR21_001646"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU6055467.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKGFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLDYEFSL
                     SPRAFYQLNPEQTEVLYSEVVKALDVSKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         5663 a         3391 c         4152 g         5487 t
ORIGIN      
        1 aaatatgtta tactatggtt atcaaagtaa atgaaaggag ttacgaatat gacgccagaa
       61 gaaatgtacc tgacagagcg attagacgta cagatagctc attttttaaa gaaaagcgtt
      121 caacatcgta ggcgctataa ggtattaaaa ataacagaaa tcgtggcagg tttcctcata
      181 gctgtctttt gtgctattcc tatgccaggt gatcgctacc gtttgatttc ggttgcctta
      241 tccagtctcg gcttgctgtg tgaggggatt atcaatttgt ataatgcaaa ggaaaattgg
      301 atttcttacc aaaaaactgc gcaactcctg gagaaagaaa aattcctcta tcaatgccaa
      361 acggaaaaat atgcaggaaa gaccaaggct tttgccctat ttgtcaagac atgcgaaggt
      421 cttatctcag aggagattaa ccagtgggaa agtatccagt caaaagaagt ggcagctagt
      481 gcagatgctc cagttaaaaa agagtaggag gtagaggaaa tgtctcaatc cagctacctg
      541 tcgcccttgc tctggttaaa aaaagaagcc gataaggaaa agatgagcgc gacccagtgc
      601 cagatatttt tcttttacta tcaaatgttt gagctcttat ttgctagaga aagcgacatg
      661 aaagacttat gtctgggaac gaaaggtttt tatttctcgc agttagagaa aaatttgctt
      721 tctggagttt cccgatttct aaaaaacttg gaggggaaag taactctcaa ggctaaccaa
      781 gaagtatcag ctcgcaaagc cctttttcta gccttgacaa ctagccaatc agattggcag
      841 gagttagctc ctgtttttga tttttatcag actatcggga ggcttgaaaa tccttctctc
      901 ttgagttctc aggacagaca acatctgatg tggatttacc agtcagcttt ggagaaggat
      961 tatattgtca aggttattgg cgacaagcat tttgtattga agagacaaga tgctactaaa
     1021 ttgacagcgc gccaaactca aactttggaa attctgagtc aatcagaaga cttggtcaat
     1081 cctgtctatg ttacattagg agaaaagggg gtgctcttgc ttgattaaga gaggagatgt
     1141 tgtagctctt tatttgcctt ttccgactat tagtagcgat ttggctgtga agaatcatat
     1201 gtatatctgt attgacaaca gcatgactaa aaacaaagag ttggttaaaa atcagacctt
     1261 caaaccagct ctcttgacca gacgtttggt caagaacttt atgatagaag agccagatct
     1321 agctcgtaat ccttttacaa gaccaacctt gattgactta gataaggtat ttatgttgga
     1381 taatacggtc attccgactt cttatctagc cagacggcga cgcaatgtct cagaagaatt
     1441 gtacgaggaa attttggatt acttagtcca accacggctg atttcgctga acaagtctga
     1501 gtttatgcaa ctcaatccag gaacttatta ggaggtagaa gatggcaaat aaagcagtaa
     1561 atgactttat actagctatg aattacgata aaaagaaact cttgacccat cagggagaaa
     1621 gtattgaaaa tcgtttcatc aaagagggta atcagctacc cgatgagttt gttgttatcg
     1681 aaagaaagaa gcggagcttg tcgacaaata caagtgatat ttctgtaaca gctaccaacg
     1741 acagtcgcct ctatcctgga gcacttctcg tagtggatga gaccttgtta gagaataatc
     1801 ccactcttct tgcggtcgat cgtgctccga tgacttatag tattgatttg cctggtttgg
     1861 caagtagcga tagctttctc caagtggaag accccagcaa ttcaagtgtt cgcggagcgg
     1921 taaacgattt gttggctaag tggcatcagg attatggtca ggtcaataat gtcccagcta
     1981 gaatgcagta tgaaaaaatc acggctcaca gcatggaaca actcaaggtc aagtttggtt
     2041 ctgactttga aaagacaggg aattctcttg atattgattt taactctgtc cattcaggcg
     2101 aaaagcagat tcagattgtt aattttaagc agatttatta tacagtcagc gtagacgctg
     2161 ttaaaaatcc aggagatgtg tttcaagata ctgtaacggt agaggattta aaacagagag
     2221 gaatttctgc agagcgtcct ttggtctata tttcgagtgt tgcttatggg cgccaagtct
     2281 atctcaagtt ggaaaccacg agtaagagtg atgaagtaga ggctgctttt gaagctttga
     2341 taaaaggagt caaggtagct cctcagacag agtggaagca gattttagac aatacagaag
     2401 tgaaggcggt tattttaggg ggcgacccaa gttcgggtgc ccgagttgta acaggcaagg
     2461 tggatatggt agaggacttg attcaagaag gtagtcgctt tacagcagat catccaggct
     2521 tgccgatttc ctatacaact tcttttttac gtgacaatgt agttgcgacc tttcaaaata
     2581 gtacagacta tgttgagact aaggttacag cttacagaaa cggagattta ctgctggatc
     2641 atagtggtgc ctatgttgcc caatattata ttacttggaa tgaattatcc tatgatcatc
     2701 aaggtaagga agtcttgact cctaaggctt gggacagaaa tgggcaggat ttaacggctc
     2761 actttaccac tagtattcct ttaaaaggga atgttcgtaa tctctctgtc aaaattagag
     2821 agtgtaccgg gcttgcctgg gaatggtggc gtacggttta tgaaaaaacc gatttgccac
     2881 tagtgcgtaa gcggacgatt tctatttggg gaacaactct ctatcctcag gtagaagata
     2941 aggtagaaaa tgactaggag aggagaatgc ttgcgacaaa aagatgcgat gatctctctg
     3001 cggatatctg aaagtttatc tcttgcctag cgatttccat tggagtatgc tcgtgatgtt
     3061 aaaatgaatc tatcaaacag aatgtgtaaa aaagtaaaaa gggtagccaa ttccttgata
     3121 tacaggggat tgattatcct ttacttgttt tagatgattg gaaattcaag aacgacacgt
     3181 atcggaaata ttttgctgtt tatatctaat acccatttat ggaaaaaatg aaattaaata
     3241 tgaacaaatc aattgctagc aatggtttag aagtgccagt gtactagtct aacttctcca
     3301 tcttgggaac acgtaaatta tactcttcga aaatctcttc aaaccaggtc agccctatcc
     3361 gcaacctcaa aacagtgttt tgagcaacct gcggctagct ttctagtttg ctctttgatt
     3421 tttattgagt attagaggtt tgcttagaaa ctcgtctatt aatttcttag aatacaatag
     3481 cgcctataag aactgttgga ttgcaaagta tttactggaa ctatgatatg tctggagtag
     3541 actgtcaaca aaaggtgcag tatgattgtt tttgtcgctt atatctacaa acttcaaaca
     3601 gtaatttgag ctgactttgt caaacttggc tgaaactttc tatttgcaga taatggtcta
     3661 gtttgttttt tgaatgtgga tgagtgtctg ttgataaaga tagaaaggta agaccatctt
     3721 agcaggtaaa gtgctatcct agcttgattt gctaataaaa tccatttcct ctagtgaaaa
     3781 tcaaaaaaac ttgtgttata ataataaaga ttaaaatgtg aaaaaaggag attcctaatg
     3841 ggacgtaaat gggccaatat cgtagccaag aaaacggcta aagatggagc taactctaag
     3901 gtatatgcaa aatttggtgt agaaatctat gtagcagcta aaaaaggtga tccagatcca
     3961 gaatcaaact cagctttgaa attcgttatc gaccgtgcta aacaagccca agtgccaaaa
     4021 cacattatcg ataaagcgat tgataaagcc aaaggaaaca cagacgaaac ctttacagaa
     4081 ggacgttacg aaggttttgg gccaaatggc tctatgctaa ttgtggatac tttgacttct
     4141 aacgtcaacc gtacagcagc caatgtccgt gcagcctttg gtaaaaacgg cggaaacatg
     4201 ggcgcttcag gttctgtttc ttacctcttt gacaacaaag gtgttattgt atttggaggt
     4261 gaagatgcag acgcagtctt tgagcaattg ctcgaagcgg atgtggatgt ggatgacgta
     4321 gaagcacaag aaggtacaat cacagtttac acagcgccaa ctgaccttca caaggctatc
     4381 gttgccctcc gtgagtctgg tattgaagaa ttccaagtga ctgaattgga aatgattcct
     4441 cagtcagaag tggaattgtc aggcgaagac cttgaaacct ttgaaaaact ttacagcgtt
     4501 cttgaagacg acgaagacgt ccaaaagatt tatacgaacg tagatgggtt ttaatttaac
     4561 ctatagaaca tgatcctaag tgagaaaatc acttgggatt tttttaatca agaaaatagt
     4621 tctcatagaa atttaattat tctccagaga actattttta tttagaaggg ggagattatg
     4681 ggtaaaccga tgttagtctt taagcgtttt ggtcatcaaa ttcacctgat ggtgcaaaag
     4741 gaagccaaac gttgcggcat tgaatttatg ggtgggccgc aaggttaggt tgtgcgtttt
     4801 ttggataatc gcgagaaaaa ccaagatttg gtcttgatta aagatatcga tcaggaactc
     4861 aatattacca agtctgttgc tagtaatctg gttaagcgta tagtgcaaaa tggtttggtg
     4921 gaattggagg cgagtcctgt tgataagcgg gctaagtttg ttcgtctgac ggacaaagca
     4981 cgttctcaga tgcaacaggt taaggctttt tttgaacgca tagacaagca gttgatggaa
     5041 gacattgatg aagatgaatt actgattttt gagaaggttc tcggtcaact acaggcaaaa
     5101 tatcaaggga ataggaggag agaataaaga aattagccaa aagaattagt agaaaagaat
     5161 gggggatgat tttactagcc attctcttta cttgcttttc ggtctatcta gagttggaag
     5221 tgccgaccta tatctcgaaa attacggatt tgctaggtag tcaagaaact aatttagatg
     5281 agttgtggca gccggcaagc atgatgatgg gaatgtcctt tcttgccttc ttgtccgtag
     5341 ttgcagttgg attttttgca tcccgagtgg cggcttctta tactagtagg ctgagaagtg
     5401 atatttttaa ccgagttttg gattactcgc agacagagat taagaaattt tcaattccta
     5461 gcctcttgac gcgtactacc aatgacatta ctcaagttca aatgttgatt actatgggct
     5521 tgcaagtggt aacgcgtggt tcaattatgg ctatctgggc tattgggaag attttaggtc
     5581 attcagaata ctggctctgg gccgtacttg tggtagtgat tgtcaacgtc ctgatgacga
     5641 ccgttttgat gacgctagcc tttccaaaac agtccttgat tcaggggttg acagataaac
     5701 tgaacagtat cactcgtgag agtttaacag gtattcgtgt cgttcgtgcc tacaatgcag
     5761 aggattatca aaatgaaaaa tttgcagcag taaatgatga attgacccgt ttgaatttgt
     5821 ttgtcaaccg tcttatggct attttgaatc ctatcatgat ggggatttca agtggtttga
     5881 gtgtagcgat ttactggatt ggggcctatg tgattaacga cgctgctccg atagcgcgtc
     5941 tgcctctctt tagtgacatg attattttca tgtcttatgc catgtaggtt gtcatgggct
     6001 tccttctcat gggagcactc ttcatcgttc ttccccgaac tatggtctct gctaagcgga
     6061 ttaatcaagt tttagatttg cattcttcta tccaaaaccc tgttcaagta cagctgactg
     6121 atgaaaactt caaaggtcag gtcgagttta aggatgtgac cttccgctat gcggcaaatt
     6181 cggaggcagt tattgaacat gttagcttta aagcagaaac tggtcaaaca gtggccttta
     6241 ttgggtcaac aggttctggt aaatcaactc tggtcaatct gattccacgt ttctacgacg
     6301 tgtcagcagg agaaattctg gtggacggtg tcaatgttca agactatgac ttctctgcga
     6361 cagctcatgc tggtcaaaag gttgccattg ttgggccgac tgggactggt aagacaacca
     6421 ttgtcaatct tttgatgaaa ttctatgaga ttgataaggg aagtattcac attgatggtg
     6481 tggataccaa ggctatgacg cgttcagaag tgcatgatgc cttttcaatg gtcttgcagg
     6541 atacctggct ctttgaagga actattcgag acaatctcat ctataatcaa atagggatta
     6601 gtgatgaacg aatgatggaa gctagtaagg ctgtgggaat tcaccacttt attatgacct
     6661 tgccagatgg ctatgatacc atcttggatg acaccgtgac cttgtctgta ggacaaaaac
     6721 aactattgac tattgctcgt acccttctta aggatgcacc gcttttgatt ttggatgagg
     6781 cgacttcttc tgttgacaca cggacagagg aattgatcca aaaagccatg gaccgtttga
     6841 tggaaggacg cacatccttt gtcattgccc accgcttgtc aaccatccga aatgcagact
     6901 tgatcttggt catgaaagat ggaaatatca tcgagcaagg caactatgag gaactgatgg
     6961 cgcaaggtgg cttctacgct gacttgtaca atagtcaatt tacagaagat gaagcagaag
     7021 aataaatcaa aagaaggctt gacggccttc tttttcttat ttatactagt acacatagaa
     7081 agagagaagt atgagtcaga aattatacaa tatgaaattt gctgctgtct acttagcctt
     7141 gattgcaaaa gttgagcgaa agggtggaaa ggcagagtca gttcaccaag tgaccagttg
     7201 gttgacaggg tatgaagtga gtgatgttct tgcttgtctg gatagggatg ttacttacgg
     7261 agattttttt agacaagcac catattatgt ccctgaacga attgcaatta cagggaagat
     7321 ttgcggtgtc cgtattgagg aaattgatga tcctctgatg caggaaatac gtcgcttgga
     7381 caagctagtg gattggcttg ccaaggggaa aacatctcaa caagttctag aaaagtatga
     7441 gaagcataaa tgaaaaatta tcaagaatgg tatcgaaata tcagctccag actaactagt
     7501 cgtccaattc ttttattcct attacgcagt ttcaatcgtt tgatgacagt cgccatgccc
     7561 ctggtctatc tgatcttgct agtcaccact tacctgcaac taggacttgg tcagcaagtt
     7621 ggggtttatg tgcttattcc tgcatcaggt tttgtggcct tgtccctgtt tcgtaagaaa
     7681 atcaatcacc cgagacctta tgaaacttgg aatacctgtc cccttcttga taaggatagt
     7741 tcgggacggt cgatgcccag tcgccatgtc ttttcggcaa ctatcatctc catggcctgt
     7801 ctgcatgcta gtctacctat tggcttagta tgcttgaact tttcagcttt gctggggttg
     7861 gtgagggttt tagggggtgt tcattatccc aaggatgtct tggttggcta tgcttgtggt
     7921 ctggtgtggg gattcctttt cttcttattc tgacatgtaa gttaagctag tcctacaacc
     7981 acttactgct tcaaattgac cacttgcttt tttgcccttg tattcctaac ttagctttga
     8041 tatagtagag tcagaaagga gatgtgatga agttacgaat tgagattgac ggcaatttag
     8101 aggagactga aattgtcatc aagaccccca ctttgacaga tgaaattgca gacttgcaac
     8161 ggctcttgca agaatccaag tctcctaggt tgatttttta caaggggacg ggtgaatatt
     8221 atctggactt gtcggaaatt ctcttctttg agacagaagg tagcaagatt tatgcccata
     8281 cccagaaaaa tgcctacgaa gttcggctca aactctatga gttagaggct atccttcctc
     8341 gctattttag tcgagtatcc aagtcaacga tcgttaatat tcggcaaatc tattcggtgg
     8401 acaagtcctt ttcaggaacg ggcaccattt ccttttatca aacccacaag gaggttcatg
     8461 tgtcacggca ttaccaatcc ctcctaaaag aaaatctaag aaatatgagg taagaacatg
     8521 aaaaagaaag catttggtat tgtgttgctt gtactagcag ctttaatatt agtacaagga
     8581 aattttggaa tcccttctct aggagggcac atttggccct tgattggtat tgcttttttt
     8641 gcctaccaat cagttggagc tttgttgcgt cgccacttaa cttcagcctc ttttacagct
     8701 ctagtagcct taatgattgc taaccacttt tatggcattt taccgattcc aaaccagaca
     8761 ctaatctggg caggagttct aatcgttctc ggagtaaata tgttgactca ttctaacaga
     8821 acttggaatg ggaaaaaatg gtggtatgat ggtgaaaaaa acattcttat agataaggaa
     8881 gttgcttttg ggacagggac tttctacaag caagaccaag aattggtaga agaccaagta
     8941 gaagttggtt ttggcaatgc aaaaatctac tatgacaatg cagagatgtt aggtgatttt
     9001 gcaactttaa atattgaagt agcttttggt aatgcaactg tctatgttcc gcaacactgg
     9061 cgtgtcgatt tgaaagtaga aacatccttt ggtgcagcca aggcggacgc tcctgtagcc
     9121 ccaaccagca aaaccttgat tatccgtgga gatgtggctt ttgggaagtt ggaaattgtc
     9181 tacgctaaat aaaaaaatct tcacttcaac catcaaaata ggcgtactaa gagtaggaaa
     9241 ttgatgcctt gctctgattt cagttctatg gttgttagac tttaaaaaat gaaatgctgc
     9301 ctttaaaagt tgtatatttt tcgatatttt ggcttttacg tttgatgtat ctatgtacta
     9361 cagcgtagat gatgtagtgt cgaatgcttt taaaaaacga atgatattgg acagtttttt
     9421 tgcctttaat tgctcaggaa ccatgaaagt cagtacttgg gtttatgaca agggagaatg
     9481 gtattatgta agttcttctg gttccatgat tgcgaatgat tgggtcaaag acaatggcaa
     9541 gtagtattat ctggcttcat caggtaagat gcttcgcaat acctacacac ctgatggtta
     9601 ctacgttggc aacttaggtg cctggcaata agaataatac tctttgaaaa tctcttcaaa
     9661 ccacgtcaac gtcgccttat ctacaacctc aaaaccgtgt tttgagcagc ctgcggctag
     9721 ctttctagtt tgctcttagt ataagaagtc cttttcctta aaggaagagg ctttttactt
     9781 gcttttctgc tgcttcctca tttgtcctga agcctttttt gtgttaaaat gaatggtatg
     9841 aaagctaaaa aaatgtggat ggcaggcttg gctctgctag gtatcggaag ccttgctctt
     9901 gctacgaaaa aagttgcaga tgaccgtaag ctcatgaaga ctcaggaaga gttgacagag
     9961 attgtgcgag accatttttc cgacatgggg gaaattgcga ccctttatgt tcaagtttac
    10021 gaaagcagtc tggagagctt ggttggtggc gtcatttttg aggatggccg tcattatacc
    10081 tttgtctatg aaaatgaaga cctagtctat gaggaggaag tcttatgata cagccagcaa
    10141 gtttagaaga attagcatct ttagtggaaa aagcgggcaa gaaggtcttc ctttttgtgg
    10201 cagactggtg tggcgattgt cgttatattt atcctgcctt accagagatt gaagagacca
    10261 atccagagtt cacctttatt cgaatggacc gagatcagta tatggatttg gccaaactct
    10321 gggatgttta cggaattcct agccttgttg ttctagaaaa ggacaaggaa atcggtcgtt
    10381 ttgtcaatcg cgaccgtaaa agtaaggagc aaattaacga ttttttagca ggattgaaat
    10441 aggagaaaaa ggaaacaatg atttttacgt ataacaaaga acatgtcggt gatgtcctta
    10501 tggtcatcgt gaaaaatagc ggagatgcca aactgaatgt ggaacgcaaa ggcaaggtag
    10561 cccgtgtttt cctcaaagaa aatggggaaa cagtagcttg gaacattttt gaggtttcga
    10621 gcttgtttga aattgcagag cgcggtcaag tctttttatc agatgagcaa gtcgctcgtt
    10681 tgaaccaaga attacaggcg gaaggtttta cagaagaaat tgttaatgat aaggaaccta
    10741 agtttgttgt tggtgaaatt gtcgagatgg tagctcatcc agacagtgac cacctcaaca
    10801 tctgccaagt tgcagtcgca agtgacaaga tagtgcaaat cgttgcagga gcacctaatg
    10861 cgcgtgttgg gttgaaaacc attgtggctc ttcctggtgc catgatgcca aaagggaatt
    10921 tcattttccc aggcgaactt cgtggtgaaa agagttttgg gatgatgtgt agtcctcgtg
    10981 aattgcattt gccaaatgct ccgcaaaaac gtggggtgct tgaattatca gaagaccaag
    11041 ttgtcggaac accgttcgac ccagcgaaac actggactgc ctaggaactt gtcagcatct
    11101 gatagaagga aataagatgg caaaaaatgt agtgattacg ggagcaacct caggaatcgg
    11161 tgaagcgatt gcgcgtgctt atctggagca gggtgatgat gtcgttctaa caggacgacg
    11221 gatagacaga ttagaaatcc tcaagtcgga gtttgcagta agctttccaa atcaaaccgt
    11281 ctggactttt ccactagatg tgacggatat ggtcatggtg aagactgttt gctctgatat
    11341 tctagaaacg atagggagga ttgatatctt ggtcaacaac gccggactgg ctcttgactt
    11401 ggctccctat caagactatg aggagttgga tatgttgacc atgttggata ccaatgttaa
    11461 aggtctgatg gcggttactc actgtttctt gccagcaatg ataaaagtca atcaaggtca
    11521 tattatcaat atggggtcaa ccgcaggaat ctacgcctat gctggtgccg ctgtttactc
    11581 agctaccaag gcagcggtta agaccttttc ggatggactg cgaattgata ccatcgcaac
    11641 ggatatcaag gtgacaacca ttcagcctgg gattgtcgaa acagatttct caactgttcg
    11701 ttttcatggt gataaagaac gagctgcgtc cgtttaccaa ggaatagaag ccttgcaagc
    11761 tcaggatatt gcagacacag tagtctatgt gaccagtcag cctcgccgtg ttcagattac
    11821 agatatgacc attatggcca atcaacaggc gacaggtttc atgattcata aaaaataaga
    11881 aatttcctcg aaaagttaca aatttctgta actttttttg atttcctacg aatagataag
    11941 taggaggaag aaaatatgta taataaagtt atcatgattg ggcgtttaac gtctacacca
    12001 gaattgcaca aaaccaacaa tgacaagtcg gtagcgcgag caactatcgc tgtcaaccgt
    12061 cgttacaaag accaaaacgg tgaacgtgaa gctgattttg ttaatatggt tctatggggc
    12121 agactagcag aaactttggc aagctacgca accaaaggta gtctcatttc cgttgatgga
    12181 gaattgcgta cccgtcgctt tgagaaaaat ggtcagatga attatgtaac cgaagtcctt
    12241 gtgacaggat tccaactctt ggaaagtcgt gcccaacgtg ctatgcgtga aaataatgca
    12301 ggccaagatt tggcagattt ggtcttggaa gaggaagaat tgccatttta atactcttcg
    12361 aaaatctctt caaaccacgt tagctttatc cacaacatca aagcaatgct ttgagcagct
    12421 tgcggctagc ttcctagttt gctctttgat tttcattgag tataaacatt aaaaagtctg
    12481 agttggtctc aggcttttta tcttgagaaa gtcagacttt tttcttgatt atttctgact
    12541 aagtgataca atagaactat gaattagcac tcaggtataa agagtgctaa taatatctat
    12601 ctcattatgg aggaaatcag atgttgaaac cattagggga ccgtgtggtc ttaaaaatag
    12661 aagaaaaaga acaaaccgtt gggggctttg ttctcgcagg ttcagcccaa gaaaaaacca
    12721 aaacagccca agttgtggct actggacaag gtgttcgtac cttgaacggt gacttggttg
    12781 ctccaagtgt taaaactgga gaccgtgtct tagttgaagc ccacgcaggt cttgatgtca
    12841 aagatggcga tgaaaagtac atcatcgtag gcgaagctaa catcttggca atcattgaag
    12901 aatagaagga gaaagtaagt atgtcaaaag aaattaaatt ttcatcagat gcccgttcag
    12961 ctatggtccg tggtgtcgat atccttgcag acactgttaa agtaaccttg ggaccaaaag
    13021 gtcgcaatgt cgttcttgaa aaatcatttg gctcaccatt gattaccaat gacggtgtga
    13081 ctattgccaa agaaattgaa ttagaagacc attttgaaaa tatgggtgcc aaattggtat
    13141 cagaagtggc ttcaaaaacc aatgatatcg caggtgatgg aactacaact gcaactgttt
    13201 tgacccaagc aatcgtccgt gaaggaatca aaaacgtcac agcaggtgca aatccaatcg
    13261 gtattcgtcg tgggattgaa acagcagttg ccgcagcagt tgaagctttg aaaaacaacg
    13321 ccatccctgt tgccaataaa gaagctatcg ctcaagttgc agccgtatct tctcgttctg
    13381 aaaaagttgg tgagtacatc tctgaagcaa tggaaaaagt tggcaaagac ggtgtcatca
    13441 ccatcgaaga gtcacgtggt atggaaacag agcttgaagt cgtagaagga atgcagtttg
    13501 accgtggtta cctttcacag tacatggtga ctgatagcga aaaaatggtg gctgaccttg
    13561 aaaatccgta cattttgatt acagacaaga aaatttccaa tatccaagaa atcttgccac
    13621 ttttggaaag cattctccaa agcaatcgtc cactcttgat tattgcggat gatgtggatg
    13681 gcgaggctct tccaactctt gttttgaaca agattcgtgg aaccttcaac gtagtagcag
    13741 tcaaggcacc tggttttggt gaccgtcgca aagccatgct tgaagatatc gccatcttaa
    13801 caggcggaac agttatcaca gaagaccttg gtcttgagtt gaaagatgcg acaattgaag
    13861 ctcttggtca agcagcgaga gtgaccgtgg acaaagatag cacggttatt gtagaaggtg
    13921 caggaaatcc tgaagcgatt tctcaccgtg ttgcggttat caagtctcaa atcgaaacta
    13981 caacttctga atttgaccgt gaaaaattgc aagaacgctt ggccaaattg tcaggtggtg
    14041 tagcggttat taaggtcgga gccgcaactg aaactgagtt gaaagaaatg aaactccgca
    14101 ttgaagatgc cctcaacgct actcgtgcag ctgttgaaga aggtattgtt gcaggtggtg
    14161 gaacagctct tgccaatgtg attccagctg ttgctacctt ggaattgaca ggagatgaag
    14221 caacaggacg taatattgtt ctccgtgctt tggaagaacc cgttcgtcaa attgctcaca
    14281 atgcaggatt tgaaggatct atcgttatcg atcgtttgaa aaatgctgag cttggtatag
    14341 gattcaacgc agcaactggc gagtgggtta acatgattga tcaaggtatc attgatccag
    14401 ttaaagtgag tcgttcagcc ctacaaaatg cagcatctgt agccagcttg attttgacaa
    14461 cagaagcagt cgtagccaat aaaccagaac cagtagcccc agctccagca atggatccaa
    14521 gtatgatggg cgggatgatg taagctttct atagaaaaca acttataaaa aacacaaaag
    14581 gagggaatga ctaacccttc tttttataat attcacttct aaattgattt gagctcttct
    14641 aacttatatg ataaaataag actagaaaaa ggagaagaac atgatcgatg tagaagaaat
    14701 tctgtgcaag atgcccccca atcagaagat taattatgac cgtgtcatgc agaaaatggt
    14761 acaagcatgg gagaaaaatg agcagcggcc aaccattctc gtgcatgttt gctgtgcccc
    14821 ttgtagtacc tatacactag aatatttgac caagtatgca gatgtgacca tctattttgc
    14881 caattctaat atccatccca aagtagaata ccataagcgg gtctatgtca tcaagaaatt
    14941 tgttagtgat tttaatgatc ggacaggaaa tacggttcag tacctagaag ctccctacga
    15001 acccaattaa taccgaaaac tagttagggg actagaggag gagcccgaag gtggcgaccg
    15061 ttgcaaggtt tgttttgact accgactgga taaaacagcg caagtggcta tggacttggg
    15121 ctttgactac tttggttcag ccttgaccat cagtcctcat aagaattctc aaaccatcaa
    15181 tagcatcgga atcgatgtgc aaaaaattta cacgacccac tatcttccca acgatttcaa
    15241 gaaaaatcaa ggctacaaac gttcagtaga gatgtgtgag gagtatgata tctatcgtca
    15301 atgttattgt ggctgcgtct atgcagccca agcccagaat attgacctgg ttcaagttaa
    15361 gaaggacgcc acagcatgct tgttggataa ggatgttgag aaagactatt ctcatatcaa
    15421 atttatagta gattgaaact agaatagtac acctctactt ctaaaacatt gttagaaatc
    15481 gatttgactg tccttatttc attttactat actgttacga aattagatat ataaatgaaa
    15541 acttgcctca aggtaggttt tttgctagta gaaaagcgat agacagaaat tgttggactc
    15601 ttaaaaaaat gaagttttgc tcaaaagagc ttcttaaatt aaaacgagca attatcagtt
    15661 caaatctgtt tcaaaagaag aacggataaa ttaatcgatg ctttgttttt gagttaggaa
    15721 gttaagcatg ccaaactgag tcgtaggaat aaatttcttt atagaaatgt gttgtaactc
    15781 tgctataatg gatttattcc tttttgtgtt tacacaattt attttatact accaaaaaaa
    15841 caaggtcagg attttgttcc tgacctttga caactttacc gattctttag ttctacatag
    15901 cgcttgtacc aaatgtttac ataggcttct gagaaaggac cacgtccatt gttaatccaa
    15961 tcaacaagaa ttttgacatg ttcttttaaa atatagtcca agtcatcaga ataattcatt
    16021 ttgcgtttgt gacgctcgta ctcttcaacg tccaagagac gtttttcccc atctgtaaaa
    16081 attttaacat ccaaatcgta atcaatatac ttcagtgctt cttcatccag atagtagggg
    16141 ctagccatat tgcaatagta agaagttcca ttatcacgaa tcatggcaat gatattaaac
    16201 caatatttct tgtgaaagta aacaatagcc ggttctcgag tgacccaacg acgaccatca
    16261 ctttcggtaa caagtgtatg atcgttgaca ccaataatgg cgttttctgt tgtttttagt
    16321 accatggtgt cccgccaagt tcggtggaga ctcccatcat gcttataact ttgaattgta
    16381 ataaagtcgc cttcttttgg aagcttcata actaaccaac tttctacaat ttataagttt
    16441 atcatttact attgtaccat aaaattacct aaaatctgtg aatttcactt ggaaatatta
    16501 aagatattct ctaagagcgc ttgctatatc cgaaaaatcg tagccctttc gtgctaaaac
    16561 ttgagttaaa cgctgcttca gttcgtatcc ttcatacttt cgagcatact tagtatattg
    16621 cttatcaagt tccttgaaga tgagttcttg agtcgtttct tgctcaactt ggctatctaa
    16681 gtcgtcaaag gcaattttag catcagaata agagaagccc ttgttagtca agttctggat
    16741 aattttatct tgcagggcac gagctggaag ttttccctca tattttttca atagtttatt
    16801 agctacacgt tgagcaactt cagaaaaatc aaattctttc aagttctctt ctatagtaga
    16861 ttttgaaatc cctttttgag ctagtttctg agtcagcaca taaggaccct tgtctcctga
    16921 aagttgattg gtattgatga tagcataagc gtactgacca tcattaatcc acttatcttc
    16981 tttaagatta gcaataactt gagaaacgat gttttcatca atatcgtatt ttttcagata
    17041 ttctctgact tctttttcag tgcgtgcttt aaaggataag tggtagaggg ccagattctt
    17101 accataagaa aattgagcaa agtcttgaat ctctttcaat tcctcttcgc ttatcacctt
    17161 atctctcgat aacataaaac gaacaattgt atcttcggtg atatagcatt tgtcgccatt
    17221 atcaagctcc atcagataga gtcttttttt cttttcaagt tttgtgattt tcatagctct
    17281 attataactc aaaatgtgat aagatagggg tatgaatctg aaagtgaaac aaaaaatacc
    17341 attaaaaatc aaacgcatgg gaattaatgg tgagggaatc ggcttttacc aaaaaacatt
    17401 agtctttgta cctggagctc tcaaaggcga agatatctat tgtcagatta cttctattag
    17461 acgcaacttt gttgaagcaa aattactgaa ggtcaacaag aagtctaaat ttcgaattgt
    17521 gccatcttgt actatttata atgaatgcgg aggctgccaa atcatgcacc tgcattatga
    17581 taagcagctg gagttcaaga cggacttact tcatcaagcg ctgaaaaaat ttgctcctgc
    17641 aggatatgaa aattatgaaa ttcgtccaac tattggaatg caggaaccaa aatattacag
    17701 agctaagtta caatttcaga ctcgaaaatt taaaaatcag gtcaaggcgg gcttatatgc
    17761 acaaaactct cactatttag tagagttgaa agactgcctg gtacaagata aggaaaccca
    17821 agtgattgct aatcgcttag cagaattact tacttatcac cagattccaa tcacggatga
    17881 gagaaaagtt ctaggtgtcc gtactattat ggtccgacgc gcgagaaaga ccggacaggt
    17941 tcagattatt attgttacaa accgccagct taatttaacc caactggtaa aagagttggt
    18001 taaaggtttt ccagaagttg tgacagtagc tgttaataca aatacagcta aaaccagtga
    18061 gatatatggt gaaaagacag agattatctg gggacaagag agtattcaag aaggtgtact
    18121 cgattatgaa ttttcactat cccctcgagc tttctatcaa ctaaatcctg aacaaacaga
    18181 agtcctttat agcgaggtag taaaagcgct ggatgttagt aaagaagacc atttgattga
    18241 cgcttattgt ggagttggaa caattggttt tgcctttgca aagaaagtaa aaacactcag
    18301 aggtatggat attattccag aagctattga agatgccaag cgaaatgcta aaagaatggg
    18361 atttgacaat actcattatg aagctggaac ggcagaagag attattcctc gttggtacaa
    18421 ggaaggctac cgagcagatg ctttgattgt tgacccacca cgtacaggtc tggatgataa
    18481 gttattagat actattctta cttatgtacc agaaaaaatg gtttatattt cttgtaatgt
    18541 ttcgaccttg gctcgtgatt tggtacgctt agtagaagtc tatgatcttc attatatcca
    18601 gtcggtcgat atgttcccac atacagctcg aactgaagct gttgtaaaat taataaaaaa
    18661 agtttaaaaa aggtgttgac aaagtttgaa aag
//
LOCUS       DAVHSI010000039        18661 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.039, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000039 DAVHSI010000000
VERSION     DAVHSI010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.039"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..89)
                     /locus_tag="VVR21_001647"
     CDS             complement(<1..89)
                     /locus_tag="VVR21_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6055468.1"
                     /translation="MWYNLLMAYSIDFRKKVLSYCERTGSITEA"
     gene            242..397
                     /locus_tag="VVR21_001648"
                     /pseudo
     CDS             242..397
                     /locus_tag="VVR21_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            597..3872
                     /gene="rexB"
                     /locus_tag="VVR21_001649"
     CDS             597..3872
                     /gene="rexB"
                     /locus_tag="VVR21_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU6055469.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3869..7519
                     /gene="addA"
                     /locus_tag="VVR21_001650"
     CDS             3869..7519
                     /gene="addA"
                     /locus_tag="VVR21_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU6055470.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLAHVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLSYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAQ
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREVIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVAVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7689..8867
                     /locus_tag="VVR21_001651"
     CDS             7689..8867
                     /locus_tag="VVR21_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055471.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEL
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYVDNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQNQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLLI
                     "
     gene            9076..14907
                     /locus_tag="VVR21_001652"
     CDS             9076..14907
                     /locus_tag="VVR21_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU6055472.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQSQLAELPNTGSK
                     NEMQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYKLTSGEKLPLPKDISGYTYIGYIKEENITSESEVSNQKSSVATPIKQQKVDY
                     SVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPALQPELPEAVVSDKGVPEVQPALPEAVVTDKG
                     EPAIQPELPEAVVTDKGEPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPV
                     EKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSP
                     DTSSENTGEVSSNPSDSTTSVGESNQPEKNRTATKPENSGNTTSENGPTEPSNGNSTE
                     DVSTESNTSNSNGNEEIKQENELDPDKMVEEPEKKLELRNVSDIELYSQTNGTYRQHV
                     SLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELENK
                     YVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDERSY
                     IKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSLANE
                     ATNGTKIKQVHVDGVLAGERGVGGLLAKADQSNIAESSFKGRIVNTYETTDAYNIGGL
                     VGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLVDQDAHIQNSYAEGDINNVKH
                     FGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGNAITGYHYTGMKVANTFSSKA
                     NRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEINPLTLPTVEPLSTSGKKDSD
                     FSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVKENSLLYQKELLSAVMMKDDQ
                     VITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANLAEYNLGNTGLLYTPNQFLYD
                     RDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELYLEDQFSKTKQNLGDSLKKLL
                     SADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERWYNFNYGQVNVKDLVMYHPDF
                     FGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKVFLP
                     NTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVYDRITSATWKYRNMVLP
                     LLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHYDY
                     WYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPAMKNFFGPVGNKV
                     VHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRNGLGPEFF
                     AKGLLQAPDQPRDATITINSILKHSKSDSTEGSRLQVLDPTKRFQNAADLQNYVHNMF
                     DLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDPADGNEVYATNVVKELTEAEA
                     RNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLMGRRI
                     AYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDGKYK
                     TWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTKTINNVDELQKLMDEAVLQDA
                     TGTRWSNYNPETDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            14959..15135
                     /locus_tag="VVR21_001653"
     CDS             14959..15135
                     /locus_tag="VVR21_001653"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6055473.1"
                     /translation="MQAGIPPDNEVSYALIYQQETLPATGSSTSELTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            15355..16206
                     /gene="ylqF"
                     /locus_tag="VVR21_001654"
     CDS             15355..16206
                     /gene="ylqF"
                     /locus_tag="VVR21_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU6055474.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            16193..16972
                     /locus_tag="VVR21_001655"
     CDS             16193..16972
                     /locus_tag="VVR21_001655"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU6055475.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRVI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            16988..18538
                     /locus_tag="VVR21_001656"
     CDS             16988..18538
                     /locus_tag="VVR21_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU6055476.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGAICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         6027 a         3675 c         3900 g         5059 t
ORIGIN      
        1 gcttctgtta tactacctgt tcgctcacaa taagagagaa cttttttacg aaaatctatt
       61 gaatatgcca taagaagatt ataccacatt gtgtactatt tttggttcat tttactatag
      121 tagattgaaa taagatacga acagcttgat tagggaaatc aaattaattt ctagaaatat
      181 tttagcatcc acggtgtact attatagttt caatttacta tagttcaatc attctatcaa
      241 gaatattgaa tatataaagg cacgtaatat taaaacttct tctgatatcg aattagagtc
      301 cgatgttgat ggcgataaat cagacaatct acccgtcgac attaagacac tgggacaaca
      361 cattgaagtg tattccgtac ctaagaaaca atcataaaac tcaaagcctt gttaccgagg
      421 cttttttatt atatgatttt cagtggccag acttattcta tctaatacaa gtaaagctaa
      481 gtatttaaga tttagcagat gatgaagaaa agaaaggatg gcctaaatat tttaacagat
      541 ttacgaggct aatcatggta taatataggg tgatgaaaaa ttccaacgag gctgagatga
      601 aattacttta tactgatatt cgaacttctt tgacagaaat tctaacaaga gaggcagaag
      661 agctagttgc agctggcaag cgggtcttct acattgcccc caactctctt tcttttgaaa
      721 aggaacgcgc cgtgctggaa tgcttgtccc agcaggcttc tttttcgatt accgtcacgc
      781 gctttgctca aatggctcgt tatctggtct tgaatgattt accagttaaa actactcttg
      841 atgatatcgg tcttgggttg gccttttaca aatgccttgc cgaactcgat cccaaggact
      901 tgcgtgttta tggcgctatt aagcaggatc ctcaattgat ccagcagtta attgagcttt
      961 accatgagat gaccaaatct cagatgagtt ttttggactt ggagaattta acagatgagg
     1021 ataagaggac ggatttactc ttgatttttg agaaagtaac agcctatctt aatcaaggtc
     1081 agttagccca gggaagtcag ttgtcccatt tgattgaggc tattgagaat gacaaggtaa
     1141 gtagtgattt taatcaaatc accttggtca ttgacggctt tactcgtttt tctgctgagg
     1201 aagagcgggt tgtggactta cttcacggca aaggtgttga gattgttatc ggggcttatg
     1261 ctagtaagaa agcctatacc agtcctttta gcgagggcaa tctttaccaa gccagcgtaa
     1321 aatttctcca tcatctggct tctaaatacc aaacgcctgc tcaggactgt tctcaaactc
     1381 atgagaagat ggatagtttt gacaaggcct ctcgtttgtt ggagtcttct tatgactttt
     1441 cagaactcgc tttggatgtc gatgagaaag accgtgaaaa tttacaaatc tggtcttgtt
     1501 tgacgcaaaa ggaggagttg gagctagtag cccgtagcat tcgtcagaaa ttacatgaga
     1561 actcagacct gagctacaag cattttcgta ttctcttggg ggatgtagct tcttaccagt
     1621 tatctctcaa aaccattttt gaccagtatc agattccttt ttatcttggt agaagcgaag
     1681 ccatggctca tcatcccttg actcagtttg tcgagtctat tttagcttta aaacgttacc
     1741 gttttcgtca ggaggatttg attaatcttc ttagaactga tttgtatact gacctcagtc
     1801 agtctgatat tgatgctttt gagcaatata tccgctatct tggtatcaat ggcttgccag
     1861 cctttcagca aaccttcacc aaatcccacc atggaaaatt taatcttgag cgtttgaatg
     1921 tcctccgcct gagaatttta gcacctcttg aaaccctctt tgccagccga aaacaaaagg
     1981 ctgaaaacct cctacaaaaa tggagtgtct ttctaaaaga aggagctgtg accaagcagt
     2041 tacaagattt gacaaccact ttggaagctg tagaacagga aagacaagcc gaagtttgga
     2101 aggctttctg ccatgtttta gaacaatttg cgactgtttt tgctggttca caggttagtc
     2161 tggaagactt cctagccttg ctccattctg gaatgagttt gtcccaatac cgtaccattc
     2221 cagcaacagt ggacactgtt ctggtgcaga gttacgattt gattgcacca ttgactgctg
     2281 actttgtcta tgctattgga ctaactcagg acaatttacc aaaaatttct caaaacacca
     2341 gtcttctgac agatgaagaa aggcaaaacc taaaccaagc gaccgaagaa ggcgttcaat
     2401 tactgattgc cagcagtgaa aatctcaaga aaaatcgcta cactatgctt tccttggtca
     2461 attctgctcg taagcagttg ttcttgtcgg ctccaagcct ttttaacgaa agtgaaagta
     2521 aggaatctgc ctatcttcaa gagttgatcc attttggatt taggcggaga gagaagagga
     2581 tgaatcacaa aggactgtct aaggaggata tggggtccta tcacagtctt ttgtctagtc
     2641 tggttgccta tcaccagcag ggtgagatga gcgatactga gcaagatttg acttttgtca
     2701 aggttctgtc gcgtgtcata ggtaaaaaac tagatcagca aggtctggaa aatccagcta
     2761 tcccaaccag tccaagcagc aagaccttag ccaaggacac cttgcaagct ctctatcctg
     2821 ccaaacagga gttttacctg tctacgtcgg gtttgacaga gttttatcgc aatgaataca
     2881 gttatttcct acgctacgtt ttaggcttgc aggaggaatt acgtttgcgt cctgatgccc
     2941 gtagtcacgg gaatttcttg catcgtatct ttgaacgcgc cttgcagttg cctaatgaag
     3001 attcctttga ccaacgtcta gaacaagcta ttcaagaaac cagtcaagaa cgcgaatttg
     3061 aagctattta tcaagaaagt ttggaagccc agtttaccaa ggaagttttg cttgatgttg
     3121 cacggacaac tggacatatt ctccgacaca atccagccat cgaaacaatc aaagaagaag
     3181 caaattttgg tggaaaagac caagccttta ttcaattaga caatggacgc agtgtctttg
     3241 tacgaggcaa ggtggaccgg attgaccgtt tgaaagctaa tggagcgata ggagtagtag
     3301 actacaaatc cagtctgact cagttccagt ttcctcattt ctttaatggg ctcaattctc
     3361 agttaccaac ctatcttgct gccctaaaaa gagaagggga gcagaacttt ttcggcgcca
     3421 tgtatttgga aatggctgaa cctgtccaat ctctgatggc ggtaaaaagt ctggcaggag
     3481 cagtggtaga agccagcaaa tctatgaaat accaagggct cttcttggaa aaagaaagca
     3541 gttatttagg cgaattttat aacaaaaaca aggcgaatca actgacagat gaggaatttc
     3601 agctcctact ggactacaat gcctatcttt acaagaaagc tgctgagaag attttagcag
     3661 gccggttcgc catcaatcct tatactgaaa atggcagaag cattgcccca tacgtccagc
     3721 aacatcaggc tattacaggc tttgaagcca attaccatct gggccaagcc cgtttcctaa
     3781 aaaagttgga cctagctgat agcaagcgtc tggtcggaga aaaactcaag caagcttggc
     3841 ttgaaaaaat aagagaggag ttgaatcgat gaagcttatt ccctttttaa gtgaggagga
     3901 gattcaaaaa ctgcaagaag cagaagcaaa ttcgagcaag gaacagaaga aaactgccga
     3961 gcaaatcgaa gctatctaca cttctggcca gaatatcctg gtctcagcat cggctggttc
     4021 tggaaagacc tttgtcatgg cagagcgcat tctggaccaa ttggcgcgtg gtgtcgaaat
     4081 ttctcaactc tttatctcaa cctttaccgt caaggctgca actgaactta aagaacgttt
     4141 agagaaaaaa atcagcaaga aaatccaaga aacagatgat gtcgagctca aacaacactt
     4201 gggtcgccag ttggcagacc tacccaacgc tgccatcgga accatggact ctttcacaca
     4261 aaaattcctt ggcaaacatg gttatctgct tgatattgca cctaatttcc gtattttaca
     4321 aaaccaaagc gagcaacttc ttctcgaaaa cgaagtcttt catgaggtct ttgaagcgca
     4381 ttaccaaggt aaacagaaag agacctttag tcatttgctg aaaaactttg ctgggcgtgg
     4441 caaggacgaa cggggtctgc gccagcaggt ctataaaatc tatgacttcc tccaatccac
     4501 cagcaatcct caaaagtggc tgagtgaatc tttcctcaaa ggctttgaga aagctgattt
     4561 taccagtgaa aaagaaaaac tgactgagca aatcaaacaa gccctttggg atttggaaag
     4621 ctttttccgt taccatctgg ataacgatgc caaggagttt gcaaaggctg cctatttaga
     4681 aaatgttcag ttaattctgg atgaaattgg ctccctaaat caggagtccg atagtcaggc
     4741 ttatcaggca gtgcttgcgc atgttgttgc catctctaag gagaaaaacg gtcgagctct
     4801 gactaatgcc agccgtaagg ctgatttgaa gcccctggct gatgcctaca acgaagagag
     4861 aaagacccag tttgctaaac taggacaatt atcagaccag ataaccattc tcgactatca
     4921 agaacgttat catggagaca cttggaaact agctaaaacc ttccaatctt tcatgagcga
     4981 ttttgtggag gcttatcgtc agagaaaacg acaggaaaat gcctttgaat tcgctgatat
     5041 cagccattac accattgaga ttttagagaa tttcccacaa gttcgtgagt cttatcagga
     5101 gcgcttccat gaagtcatgg tcgatgagta tcaggatacc aaccatattc aagaacggat
     5161 gctggaattg ttgtctaatg gccacaatcg ctttatggtg ggagatatca agcaatccat
     5221 ctatcgtttc cgtcaggcag acccgcagat tttcaatgag aaattccaac gctatgcgca
     5281 aaatccccaa gaaggtaagc tcattctcct caaggaaaat ttccgtagta gttcagaagt
     5341 gctgtcagca accaatgatg tctttgaacg tctcatggac caagaggtcg gcgaaatcaa
     5401 ctatgataac atgcaccagc ttgtttttgc caataccaaa ctgactccca atccagacaa
     5461 caaggccgaa tttctcctct acgacaagga cgatacaggt gaggaagaag agagtcaaac
     5521 agaaacgaaa ctaacaggcg aaatgcgctt agttatcaag gagatcctta aacttcatca
     5581 ggaaaaaggt gttgccttta aggaaattgc ccttctgacc tctagtcgta gtcgtaatga
     5641 ccaaattcta cttgccctgt ctgagtacgg gattcctgtc aaaactgacg gagagcaaaa
     5701 caattatctc caatccctag aagtgcaagt catgctagac actcttcgtg tcattcacaa
     5761 tcccctgcaa gactacgcct tggttgccct tatgaagtct ccaatgtttg gttttgatga
     5821 ggatgagcta gcacgtttgt cccttcagaa agcagaggat aaagtccacg aaaatctcta
     5881 tgagaaactg gtcaatgcac aaaaaatggc aagtagtcaa aaaggcttga ttcacacagc
     5941 tctagctgaa aaactaaagc aattcatgga tatcctagct tcttggcgct tgtatgccaa
     6001 aacccattct ctctatgact tgatttggaa gatttacaac gaccgttttt attatgacta
     6061 tgttggggct ttgccgaatg gtcctgctag gcaggccaat ctctatgccc tagcactgcg
     6121 tgctgatcaa tttgaaaaga gcaatttcaa aggtttgtcg cgttttattc gtatgattga
     6181 ccaagtctta gaagcccagc acgatttggc aagcgtggcc gtcgcaccgc caaaagatgc
     6241 agtagagctc atgaccatcc acaagagtaa agggctggag tttccttacg tctttatcct
     6301 caatatggat caagatttca acaagcaaga ctctatgtca gaagtcattc tcagtcgtca
     6361 gaatggtctt ggtgtcaaat atattgctaa gatggagaca ggggcagtag aagaccacta
     6421 tcctaaaacc atcaaactct ccattcctag tctgagctat aggcagaacg aagaggaatt
     6481 acagctagca agctattctg agcagatgcg tttgctgtat gttgctatga cgcgggctga
     6541 gaaaaagctc tatcttgtcg gcaagggttc tcgtgaaaag ctggaagcca agcaataccc
     6601 agcagcccaa aatgggaaac taaatagcaa tactagactg caagcacgga atttccaaga
     6661 ttggctttgg gctatcagta aagtgtttac taaggacaag ctcaacttta gttatcgttt
     6721 tattggcgaa gatcagttga ccagagaagt tatcggagag ttggaaacca agagtcctct
     6781 ccaagatagc tcccaagcag acaatcgtca gtcagatacc atcaaagaag ctctggaaat
     6841 gctgaaggag gtggcagttt ataatactct tcaccgcgca gctattgaac ttcctagtgt
     6901 tcaaacccca agtcaaatca agaaattcta cgaaccagtt atggatatgg aaggtgtcga
     6961 gattgctggt caaggtcagt cagtaggcaa gaaaatcagc ttcgatttgc cagatttttc
     7021 aaccaaagaa aaggtaactg gagctgagat tggtagtgct actcacgaac tcatgcagag
     7081 aattgacctc agccagcaac taacccttgc tagcctaaca gaaacactca aacaagttca
     7141 aactagccaa gctgtcagag acaagatcaa tcttgataaa attcttgctt tctttgacac
     7201 agtactcggt caggaaattc ttgctaatac cgaccatctc tatcgcgagc aacctttctc
     7261 catgctcaaa cgagaccaaa agagtcagga agactttgtt gtccgtggta tccttgatgg
     7321 ctatctgctt tacgaaaaca aaattgttct gttcgactac aagacagacc gctatgatga
     7381 accaagtcaa ctcgtagacc gctatcgtgg tcagttagct ctatacgaag aggctttatc
     7441 acgagcctat tcgattgaaa atattgaaaa atacttgatt ttactcggta aagacgaggt
     7501 tcaagttgta aaagtataac ttatactctt tgaaaatctc ttcaaaccac gtcagcttcg
     7561 ccttgctgta tatatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     7621 ttgagctgac tgcggctagc tttctagttt gctctttgat ttttattgag tattagaaag
     7681 gagacctcat gacacttcca gttagaaaat ccctgcacga tgcagtttta caggcttcga
     7741 aagcggatac ttgggaacaa gctaccaagg aatggaatga agtttccttg atttttaacg
     7801 gtatcggccg tagcaattgt gtctgtggaa atgccatcaa atacgcttat gaactcttta
     7861 acggtgtcac aggccaacgc ctctttccaa ttggtagcga ctgtgttcgt cattttcatc
     7921 gattgtccct tgaccagcaa ttggaagagg aagaaaaact gctcagaaag gttgaaaatc
     7981 taaccagaaa agctcagaaa aaggaaaaaa tcaaggtcaa taaaagtgac tttgacgagc
     8041 gacttctaaa atggctctgg gaaaaaggtg ttttcaaacc caatcgtggc aatcaatttg
     8101 cgcctgagag agactaccag cttttcctag aagtctttca gggaggaagt tggaccaagg
     8161 cggaactaaa gaaaaaggct cggatggaag aagtccttga aaagtgtatc aaaccctttt
     8221 tacttgggaa atcggatgac caactctacc ttgtcaagct aggcaaggag aaaattgact
     8281 acgaacaaga actccgtatc caggcagaga aagaacgcaa gaagagggat aaaatcgcca
     8341 agcaatatgt agacaatctg gttctagcca tgggacccgc agagcgtgct tatcaagatt
     8401 actttggctt tacagagacc ctgactcaag aagaacgcaa gtgggaaaaa attctttttg
     8461 gtaaaaatag agcagaacgg gctatcaaag ccaaacaata ccaaaaagag ctggaaaaag
     8521 accaacgaat tgccagtcag gatccaattg aaagaaaaca gaatcagact tggctcctca
     8581 attcctattt tcgtgagctt cctgaagaaa aagctcgatt ttctaggctc ttattagaat
     8641 atagaaaaag tggtgaagta cccttttcaa ctgaatacct gtcagatcat ctcatcgact
     8701 ttttctataa aatgaaagcc tttgaatttg aaatcgcacc agaacaagtc cgagattttc
     8761 taaaaaaaag cctgcaggaa gaccatcgct catcagcaca aggaagctgg atagaaggaa
     8821 ttctcctcaa ctgtctcaaa ccatttttag aacgattact gatatgagta acacctaccg
     8881 tgtaaatttc atggtaggtg ttattgtacc cccaaataat ataaaacaaa gtatgaaagc
     8941 gcatctcaat tttaagactt ttttgtaaat taagagtata attaaggtat actgcctttt
     9001 ctatagataa tagataatac actaatataa taaaggtctt tgtaacatat ataaatttta
     9061 tttcaaggag gaataatgga aaagtatttt ggtgaaaaac aagagcgttt ttcatttaga
     9121 aaattatcag taggacttgt atctgcaacg atttcaagtt tattttttat gtctgtatta
     9181 gctagttcat ctgtggatgc tcaagaaact gcgggagttc actataaata tgtggcagat
     9241 tcagagctat catcagaaga aaagaagcag cttgtctatg atattccgac atacgtggag
     9301 aatgatgatg aaacttatta tcttgtttat aagttaaatt ctcaaagtca actggcggaa
     9361 ttgccaaata ctggaagcaa gaatgagatg caagccctag ttgctggtgc tagcttagct
     9421 gctctgggaa ttttaatttt tgccgtctcc aagaaaaagg ttaagaataa aacggtatta
     9481 catttagtat tggttgcagg gataggaaat ggtgtcttag tttcagtcca tgctttagaa
     9541 aatcatcttt tgctaaatta caatactgac tataaattga cctctggaga aaaattacct
     9601 cttcctaaag acatttcagg ttacacatat attggatata tcaaagagga aaacataact
     9661 tctgagtctg aagtaagtaa tcaaaagagt tcagttgcca ctcctataaa acaacaaaag
     9721 gtggattata gtgttacacc gaattttgta gaccatccat caacagtaca agctattcag
     9781 gaacaaacac ctgtttcttc aactaagccg acagaagttc aagtagttga aaaacctttc
     9841 tctactgaat taatcaatcc aagaaaagaa gagaaacaat cttcagattc tcaagaacaa
     9901 ttagccgaac ataagaatct agaaacgaag aaagaggaga agatttctcc aaaagaaaag
     9961 actggggtaa atacattaaa tccacaggat gaagttttat caggtcaatt gaacaaacct
    10021 gaactcttat atcgtgagga aactatagag acaaaaatag attttcaaga agaaattcaa
    10081 gaaaatcctg atttagctga aggaactgta agagtaaaac aagaaggtaa attaggtaag
    10141 aaagttgaaa tcgtcagaat attctctgta aacaaggaag aagtttcgcg agaaattgtt
    10201 tcaacttcaa cgactgcgcc tattccaaga atagtcgaaa aaggtactaa aaaaactcaa
    10261 gttataaagg aacaacctga gactggtgta gaacataagg acgtacaatc tggagctatt
    10321 gttgaacctg cacttcagcc tgagttgccc gaagctgtag taagtgataa aggcgtacca
    10381 gaagttcaac cagcgttacc ggaagcagtc gtaaccgaca aaggtgagcc cgcaattcag
    10441 cctgaattac ccgaagctgt tgtaaccgac aaaggtgagc ccgctgtcca acctgaatta
    10501 cccgaagctg tagtaagtga taaaggtgaa ccagagcagg tagcaccatt gccagaatat
    10561 aaggggaata ttgagcaagt aaaacctgaa actccggttg agaagaccaa agaacaaggt
    10621 ccagaaaaaa ctgaagaagt tccagtaaaa ccaacagaag aaacaccagt aaatccaaat
    10681 gaaggtacta cagaaggaac ctcaattcaa gaagcagaaa atccagttca acctgcagaa
    10741 gaatcaacaa cgaattcaga gaaagtatca ccagatacat ctagcgaaaa tactggggaa
    10801 gtgtccagta atcctagtga ttcgacaacc tcagttggag aatcaaatca accagaaaaa
    10861 aacagaactg caacaaaacc agaaaattca ggtaatacaa catcagagaa tggaccaaca
    10921 gaaccatcaa acggaaattc aactgaggat gtttcaaccg aatcaaacac atccaattca
    10981 aatggaaacg aagaaattaa acaagaaaat gaactagacc ctgataaaat ggtagaagaa
    11041 ccagagaaaa aactcgaatt aagaaatgtt tctgatattg agttgtatag tcagacgaat
    11101 ggaacctaca gacaacatgt ttcattggat ggaattccag agaatacgga tacttacttt
    11161 gtcaaggtaa aatcttcagc atttaaagat gtctatatac cagtagcttc aataactgaa
    11221 gagaaaagaa atgggcagtc agtttataaa atcacagcca aagctgagaa actccagcaa
    11281 gaactagaaa ataaatatgt cgacaatttc accttctacc tcgataagaa ggctaaagag
    11341 gaaaatacaa actttacttc ctttagcaac ctggtcaaag ctataaacca aaatccctct
    11401 ggaacctatc atttagcggc cagcctgaat gctaacgaag tggagcttgg tcctgatgaa
    11461 agatcctata tcaaggacac ctttactggt cgtttaatcg gtgaaaaaga tggcaagaat
    11521 tatgctatct ataatttgaa aaaacctctg tttgaaaact tgagtggtgc tacagtagaa
    11581 aaactgagtc taaaaaatgt tgctatttca gggaaaaatg atattggttc actggcaaat
    11641 gaagctacga atggcacaaa gattaaacaa gttcatgttg atggtgttct ggctggagaa
    11701 cgtggtgtcg gtggtttgtt ggctaaggca gaccaatcaa acatcgcaga gagcagtttc
    11761 aagggaagaa ttgtcaatac ctatgaaacg actgatgcct acaatattgg cggtctggtc
    11821 ggtcatttaa caggaaaaaa tgcgtctatt gctaaatcca aagcgacagt aaccatttcg
    11881 tcaaacacca ataggtcaga tcagactgtc ggtggtcttg caggtctagt agaccaagat
    11941 gcgcatatac agaacagtta tgcggaaggt gatattaata atgtcaagca ctttggtaaa
    12001 gtcgctggtg tggcaggata tttgtgggat cgaacttctg gtgaggaaaa acacgctggt
    12061 gaattgacca atgttcttag cgatgtcaat gtaacaaacg gaaatgccat cactggatac
    12121 cactatacag gaatgaaggt agctaataca tttagtagta aggctaatag agttttcaat
    12181 gtcactttag agaaggatga ggtcgtcagc aaggaatcct ttgaagaaag aggaacaatg
    12241 ctagatgctt ctcaaattgt aagcaaaaaa gcagaaataa atcctctcac tctaccaacg
    12301 gtggaacccc tctcaacaag tggcaagaaa gacagtgatt tttctaagat agcccattat
    12361 caagctaacc gtgctttggt ttataagaac attgaaaaat tgttaccttt ttataataag
    12421 tcaaccatcg tcaaatacgg aaacctggtt aaggagaaca gtctcttata ccaaaaagaa
    12481 ctcttatctg cagttatgat gaaggatgac caagtaatca cagatattgt ttccaacaaa
    12541 cagactgcaa acaaactctt acttcactat aatgaccatt catctgagaa atttgatctc
    12601 aagtaccaga ctgattttgc caatctagca gaatataatc taggtaatac gggacttctc
    12661 tacactccta accaattctt atatgatcga gactctattg ttaaggaagt cttgcctgag
    12721 ttgcagaagc ttgattacca gtcagatgct atcagaaaga cacttggtat ttctccagaa
    12781 gttaagttaa ccgagctcta tttagaagac cagttctcca aaacaaaaca aaatctggga
    12841 gacagcttga aaaaactttt gtcagcagat gccggtctag ctagcgataa ctcagtcacc
    12901 agaggctatc ttgtagataa aatcaagaat aataaggaag ccttgctact cggtttaact
    12961 tatttagaac gttggtataa ctttaactat ggtcaagtga atgtcaaaga cctagttatg
    13021 tatcatccag acttctttgg taaaggaaat acttccccac tagatactct gattgagtta
    13081 ggtaaatctg gctttaacaa tcttctagct aagaataatg tcgatactta tggtatcagt
    13141 cttgccagtc aacatggaac gacagatttg tttagcacgc tggaacatta ccgaaaagtc
    13201 tttttaccaa atacaagcaa taatgactgg tttaaatcag agactaaggc ttacattgtc
    13261 gaagaaaaat ccactatcga agaggtgaaa acgaagcaag ggttagctgg caccaagtat
    13321 tctatcggtg tttatgatcg tatcacgagt gccacatgga aataccgcaa tatggtcttg
    13381 cctctcctga ccttgccaga gagatccgta tttgtcatct cgaccatgtc tagtctagga
    13441 tttggagctt atgatcgcta ccgcagtagt gaccataaag cgggcaaggc tctcaatgat
    13501 tttgttgaag aaaatgcgcg tgaaacagcc aaacgtcagc gagatcacta cgattattgg
    13561 tatcgtattt tagatgaaca gtcacgcgaa aaactctatc gtacgattct cctttatgat
    13621 gcctataagt ttggggatga cacaacatca ggaaaagcta cagcggaggc taagtttgat
    13681 agctccaatc cagctatgaa gaacttcttt ggaccagttg gcaataaggt agtacacaac
    13741 cagcatggag cctacgctac aggggacggc gtctactata tgtcttaccg catgctggac
    13801 aaggatggag ccattactta tacccatgaa atgacccatg attcggatca ggatatttac
    13861 cttggtggct atggtcgaag aaatggcttg ggaccagagt tcttcgcaaa aggcttattg
    13921 caagcccctg accaaccacg tgacgcaacc attaccatta attctatctt gaaacactca
    13981 aaatcagata gtacagaggg atcccgtctt caagtcttgg atccgacaaa gagattccaa
    14041 aacgcagcag atcttcagaa ctatgtccat aacatgtttg accttatcta catgatggaa
    14101 tatctcgaag ggcagtcaat cgttaataaa ctaagtgttt accagaaaat ggcggctctc
    14161 agaaaaattg agaacaagta tgtgaaagat ccagcagatg gaaatgaggt ttatgccact
    14221 aacgtagtca aagaattgac agaagcagag gcccgaaacc tgaatagttt tgaaagtttg
    14281 attgaccaca acatcttatc agctcgtgag taccagtctg gcgactatga acgaaatggc
    14341 tactatacca tcaaactctt tgccccaatc tattcagctc tcagcagtga gaaaggcaca
    14401 ccaggggacc ttatgggacg taggattgcg tacgaacttt tggctgccaa aggctttaag
    14461 gatggtatgg taccatatat ttccaaccaa tacgaagaag atgctaaaca acaagggcaa
    14521 actatcaatc tttatggtaa agaacggggc ttggtgaccg atgagcttgt tttgaaaaag
    14581 gtatttgatg gtaagtataa aacttgggca gaatttaaga cagctatgta ccaagaacgg
    14641 gtggatcagt ttggaaactt gaagcaggtg acctttaaag atccgacaaa accatggcca
    14701 agatatggca caaagactat caataatgtg gatgaattgc agaaactaat ggatgaagct
    14761 gttttgcagg atgctacagg tacacgttgg agtaattata atccagaaac ggacagtgcc
    14821 gtccataagt tgaagagagc aatctttaaa gcctatcttg accaaacaaa tgattttaga
    14881 agttcaattt ttgagaataa aaaatagtgt ttactattag gaaataaagt ttaaaaaggt
    14941 gatgaagaac aaaccaagat tcaagcagga attcctcctg ataatgaagt aagttatgct
    15001 cttatttatc agcaggaaac tcttcctgca acaggttcat caacttctga gcttacagct
    15061 ttaggcctat tagctgttgg tagtttagtt cttttggttc ataatatgac gggaacagtt
    15121 ttttgctccc tctgaaaagt catcatttga tggctttttt ctatataggg taaaagatag
    15181 ggtaaaaggc tatcatcgga caaaataaag aaggcatgat ataatataaa gtagatttct
    15241 atgtcataaa acaagaactg tttggacatc attcatttga aaactctcta tgttcaaaca
    15301 atagtaaaat aaaatagggg tgctaaaccc ttgctacgaa aggaaaaaaa tgcaatggct
    15361 actattcaat ggtttcctgg tcacatgtct aaagcgcgtc gacaggtgca ggaaaattta
    15421 aaatttgttg attttgtgac gattttagta gatgcacgct tgcctctatc tagtcaaaat
    15481 cctatgttga ccaagattgt tggtgataaa ccaaaactct tgattttaaa caaggccgac
    15541 ttggctgatc cagcaatgac caaggaatgg cgtcagtatt ttgaatcaca aggaatccag
    15601 acgctagcta tcaactccaa agagcaagtg actgtaaaag ttgtaacaga tgcggccaag
    15661 aagctcatgg ctgataagat tgctcgccag aaagaacgtg ggattcagat tgaaaccttg
    15721 cgtaccatga ttattgggat tccaaacgct ggtaaatcaa ctctgatgaa ccgtttggct
    15781 ggtaaaaaga ttgctgttgt tggaaacaag ccaggggtca caaaaggtca acaatggctt
    15841 aaaaccaata aagatctgga aatcttggat acaccgggga ttctctggcc taagtttgag
    15901 gatgaaactg ttgcacttaa gttggcattg actggagcta tcaaggatca gttgcttcct
    15961 atggatgagg ttaccatttt tggtatcaat tatttcaaag aacattatcc agaaaagctg
    16021 gctgaacgct tcaaacaaat gaaaattgaa gaagaagcgc ctgtgattat tatggatatg
    16081 acccgcgccc tcggtttccg tgatgactat gaccgttttt acagtctctt cgtgaaggaa
    16141 gtccgtgatg gcaaactcgg taactatacc ttagatacat tggaagacct cgatggcaac
    16201 gattaaagaa atcaaagaac tccttgtgac agtcaaggag ttagaaagcc ctattttttt
    16261 agagcttgaa aaggataatc gctcaggagt tcaaaaggaa atcagcaagc gtaaaagagt
    16321 cattcaagct gaattagatg aaaatttgcg cttggaatcc atgctttctt atgaaaaaga
    16381 actttataag caaggattga ccttaattgc aggtattgat gaggttggtc gtggtcctct
    16441 tgctggtcct gtagtcgctg cggccgttat tttacctaaa aattgtaaga ttaaaggtct
    16501 caacgacagc aagaaaattc ctaaaaagaa acatctggag attttccaag ccgttcaaga
    16561 ccaagccttg tcgattggaa ttggtatcat agataatcag gtcatcgacc aagtcaacat
    16621 ctatgaagca accaaactag ccatgcaaga agcaatctcc cagctcagcc ctcaaccaga
    16681 gcaccttttg attgatgcca tgaaactgga cttgcccatt tcacaaacct ccattatcaa
    16741 aggagatgcc aactccctct ctatcgcagc agcatctata gtagccaagg taacacgtga
    16801 tgaattgatg aaagaatacg atcagcagtt ctctggctat gatttcgcta ctaatgcagg
    16861 atatggcaca gctaaacatc tggaaggcct cacaaaacta ggagttaccc caattcaccg
    16921 aaccagcttt gaacccgtta aatcactggt tttaggtaaa aaagaaagtt aattgaaagg
    16981 aaataccatg gaggaacagt cggaaatagt ccgttctaag aaagaattcg cttttgcatc
    17041 cagcactata ctatcccaag ttggtcgagg aatcattgtc ggcctcatcg ttggaattat
    17101 cgtcggatcc tttcgtttct taattgaaaa gggcttccac ctgatacaag gagtttatca
    17161 agatcaaggg tacttagtgc gcaatctttt tgtactggtt ttgttttata tactcatctg
    17221 ttggctcagt gccaaactaa cacggtcaga aaaagatatt aaaggctcag gaattcctca
    17281 agtcgaagcc gaactgaaag gcctcatgtc cctcaactgg tggggcattc tttggaaaaa
    17341 atatgtgcta ggtattcttg ctattgccag tggactcatg ctgggtcgag agggacccag
    17401 cattcaactt ggagcagttg gtggtaaagg aattgccaag tggctcaaat ccagtccagt
    17461 agaggaacgt tccttgattg ccagtggagc tgcagcaggt ttagccgcag cctttaatgc
    17521 tcctattgca gcacttctct ttgttgtaga agaagtctat caccattttt cgcgcttttt
    17581 ctgggtctca actctagcag ccagcatcgt agcaaacttt gtgtctctac tcatgttcgg
    17641 tttgacacca gtattggata tgccagataa cattcctccc atgaccctag atcagtattg
    17701 gatatatctc gtcatgggaa ttttccttgg attttcaggt tttctctatg agaaagctgt
    17761 attaaacgtt ggaagagttt atgacttgat tggtcaaaaa atccatttgg atagagctta
    17821 ttatcccatc ttggctttta tccttatcat accagtcgga atcttcttac ctcaaatcat
    17881 tggtggcgga aatcagcttg tcctttcttt aactgaacaa aattttagtt tccaagtttt
    17941 attagcttac tttttgatcc gctttatttg gagtatgatt agctatggaa gtggactgcc
    18001 aggaggaatt ttcctcccca ttttagctct tggttctttg cttggtgcct taattggtgc
    18061 tatctgtgtc aatcttggac ttgtcagtca agagcaattc cctatatttg tcattctagg
    18121 aatgagtggc tattttggag ccatatcaaa agctccctta accgctatga tcctcgtaac
    18181 tgagatggta ggagatattc gcaacctcat gccacttggt cttgtcactc ttgtttctta
    18241 tattatcatg gatttgctca aaggtacgcc agtctatgaa gccatgctgg aaaaaatgct
    18301 tccagaagaa gtatctagcg aaggagaagt tacacttatc gaaataccag tttctgataa
    18361 aattgctggg aaacaagttc atgaactcaa cttaccacac aacgtcctca tcacaactca
    18421 agtccataat ggcaagagcc aaacagttaa cggctcaacc agaatgtatc tgggtgatat
    18481 gattcacctg gttattccaa aaagtgaaat tggaaaagtc aaagatttgt tgttgtagta
    18541 tgagcattta cataatttat gttatgtaaa tgctcagctt gatttattta gaaaaccgat
    18601 tctcagaaat gagatcggtt attttttact gatgaggaat tttacatata aataattgaa
    18661 c
//
LOCUS       DAVHSI010000040        18162 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.040, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000040 DAVHSI010000000
VERSION     DAVHSI010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.040"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..482)
                     /locus_tag="VVR21_001657"
     CDS             complement(<1..482)
                     /locus_tag="VVR21_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU6055477.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     V"
     gene            complement(544..2166)
                     /locus_tag="VVR21_001658"
     CDS             complement(544..2166)
                     /locus_tag="VVR21_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6055478.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            2372..3397
                     /gene="trpS"
                     /locus_tag="VVR21_001659"
     CDS             2372..3397
                     /gene="trpS"
                     /locus_tag="VVR21_001659"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU6055479.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            3549..5027
                     /gene="guaB"
                     /locus_tag="VVR21_001660"
     CDS             3549..5027
                     /gene="guaB"
                     /locus_tag="VVR21_001660"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU6055480.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(5078..6175)
                     /gene="recF"
                     /locus_tag="VVR21_001661"
     CDS             complement(5078..6175)
                     /gene="recF"
                     /locus_tag="VVR21_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU6055481.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(6178..6546)
                     /gene="yaaA"
                     /locus_tag="VVR21_001662"
     CDS             complement(6178..6546)
                     /gene="yaaA"
                     /locus_tag="VVR21_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU6055482.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            6705..7955
                     /locus_tag="VVR21_001663"
     CDS             6705..7955
                     /locus_tag="VVR21_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6055483.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILDETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            7952..9235
                     /locus_tag="VVR21_001664"
     CDS             7952..9235
                     /locus_tag="VVR21_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU6055484.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTNLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            9277..10098
                     /locus_tag="VVR21_001665"
     CDS             9277..10098
                     /locus_tag="VVR21_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6055485.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            10109..10654
                     /gene="pgsA"
                     /locus_tag="VVR21_001666"
     CDS             10109..10654
                     /gene="pgsA"
                     /locus_tag="VVR21_001666"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU6055486.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAIPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            10651..11478
                     /locus_tag="VVR21_001667"
     CDS             10651..11478
                     /locus_tag="VVR21_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6055487.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            11463..12302
                     /locus_tag="VVR21_001668"
     CDS             11463..12302
                     /locus_tag="VVR21_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU6055488.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            12295..13089
                     /locus_tag="VVR21_001669"
     CDS             12295..13089
                     /locus_tag="VVR21_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6055489.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRIQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            13148..13966
                     /gene="mreC"
                     /locus_tag="VVR21_001670"
     CDS             13148..13966
                     /gene="mreC"
                     /locus_tag="VVR21_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU6055490.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            13966..14460
                     /gene="mreD"
                     /locus_tag="VVR21_001671"
     CDS             13966..14460
                     /gene="mreD"
                     /locus_tag="VVR21_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU6055491.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            14554..15732
                     /locus_tag="VVR21_001672"
     CDS             14554..15732
                     /locus_tag="VVR21_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU6055492.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            15956..16735
                     /gene="rpsB"
                     /locus_tag="VVR21_001673"
     CDS             15956..16735
                     /gene="rpsB"
                     /locus_tag="VVR21_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU6055493.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            16814..17854
                     /locus_tag="VVR21_001674"
     CDS             16814..17854
                     /locus_tag="VVR21_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU6055494.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT         5696 a         2929 c         3815 g         5722 t
ORIGIN      
        1 acatctagcc aggtttttat ctctaattga ctgacagtga aactcatcag agcataggaa
       61 gtagataagg ctagttttaa agtctgaggg atagattgaa acaatttatt caaactaaaa
      121 aaggttgaca gaccaatcaa tccaaatttt aagagagtgg tcagatagac agcatctggc
      181 atattcgtta gatcaaaaaa gtaaactaga ggcgcgagaa aactacccaa gtaataacta
      241 gatagggcat agaagtttag ccctagacca cttgtaaagg tgtaaaacag actactattt
      301 ccatgtagga tatttcgtaa ggctacatca aaaataacgt attgatgaaa gccatctcct
      361 aatagaggag agttgtcgct attccagtag ataccttgag atagatatac tccagacata
      421 atcactacag gaatgatgaa agaaataaaa taggttcgat atgtttttaa aaatgatttc
      481 atgttacctc gtagaatgat agaaaactca gttggttaac ccaactgagt tttgaagttt
      541 tatttagtct ttccaaagtt ctttaacttt tgcttgtact tctgcatttt ctaggaattc
      601 atcgtaggtt tcatcgatac ggtcaatgac gccattttta gataagacaa tgatatggtt
      661 agccaaagtt tgaataaatt cgtggtcatg gctagcaaag atgattgatt ctttaaagtt
      721 tttcaatcca tcattcaagc ttgagataga ttccaagtcc aagtgatttg ttggatcatc
      781 aagtacaagg acatttgatt ttaagagcat gagttttgaa agcatgacac gaactttttc
      841 tccccctgac aagacattta caggtttgtt aacttcatct ccagagaaga gcatacggcc
      901 gaggaagcca cgtaggaaag tattgtcatc ttcttcttta cttgcgaatt gacgcaacca
      961 gtcaagaatt gattctcctc ctgcaaaatc agctgagtta tcttttggta ggtaagattg
     1021 actagttgta actccccact tgacagttcc ttcatagtca atatctccca tgattgcacg
     1081 aattaatgca gtcgtttgaa tatcattttg tccaataagt gctgtcttat catctggacg
     1141 caagatgaaa ctaatattat ccaagatagt ttcaccatca atctttacag ttagattttc
     1201 tactgtcaag agatcattac caatctcacg ttccgcttta aagttgataa atggatattt
     1261 acgactagat ggcacaatct cttctagctc aatcttatca agcattttct tacgtgatgt
     1321 tgcctgcctt gacttagaag cattggcaga gaaacgagca acaaattctt gcaattgttt
     1381 aattttttct tctgctttag cattacggtc tgctagcaat ttagcagcaa gctcagaaga
     1441 ttccttccag aagtcgtagt ttccgacata gagtttgatt tttccaaagt caaggtcggc
     1501 catgtgagta caaactttgt ttaagaagtg acggtcgtgg gatactacga taactgtgtt
     1561 atcaaagtca atcaagaagt cttctaacca agtaatcgat tggatatcca aaccgttagt
     1621 aggctcgtcc aagagaagaa catctggttt accaaaaagt gctttggcga ggagaacctt
     1681 tactttttca ccgttggcca attcgctcat gttttggtag tgtaattctt ctggaatgtt
     1741 taggttttga agtagttgag aggcttcact ctctgcttcc caacctccaa gttcggcaaa
     1801 ttctccttcg agttcggcag cacgaacccc gtcctcgtct gagaaatctt ccttcatgta
     1861 gatagcatct ttctctttca tgatgctata aagtttttca tttcccatga taacgacatc
     1921 aatggcacgt tcatcttcgt agtcaaagtg attttgacga agaacagaga gacgttcatc
     1981 tggaccaaga gagatgtgac cagtagtagg ttcgatatct ccagctaaaa tttttaaaaa
     2041 ggttgatttt ccggcaccat tagcaccgat taatccgtaa gtatttcctt ctgtaaattt
     2101 gatattgaca tcatcaaaaa gtttgcgatc actaaaacgt agtgaaacat cagatactgt
     2161 aagcaatatt tttctcctat atgtgtaata tatttattct actagaaaat acagaaatat
     2221 tcaaattttt atttgtcaat tttgtgtaaa atatatttac agtatccttt acacaaatct
     2281 gtaaaaagca aggctgattt attttgataa attacggtta tttcattaaa aaaatgctat
     2341 aattgaaagg actatatcga aggagaacaa aatgactaaa cccattattt taacaggaga
     2401 ccgtccaaca ggaaaattgc atattggaca ttatgttgga agtctcaaaa atcgagtatt
     2461 attacaggaa gaggataagt atgatatgtt tgtgttcttg gctgaccaac aagccttgac
     2521 agatcatgcc aaagatcctc aaaccattgt agagtctatc ggaaatgtgg ctttggatta
     2581 tcttgcagtt ggattggatc caaataagtc aactattttt attcaaagcc agattccaga
     2641 gttggctgag ttgtctatgt attatatgaa tctagtttcg ttagcacgtt tggagcgaaa
     2701 tccaacagtc aagacagaga tttctcagaa aggatttgga gaaagcattc cgacaggatt
     2761 cttggtctat ccaatcgctc aagcagctga tatcacagct ttcaaggcta attatgttcc
     2821 tgttgggaca gatcagaaac caatgattga gcaaactcgt gaaattgttc gttcttttaa
     2881 caatgcatat aactgtgatg tcttggtaga gccggaaggt atttatccag aaaatgagag
     2941 agcagggcgt ttgcctggtt tagatggaaa tgctaaaatg tctaaatcac taaataatgg
     3001 tatttattta gctgatgatg cggatacttt gcgtaaaaaa gtaatgagta tgtatacaga
     3061 tccagatcat atccgcgttg aggatccagg taagattgag ggaaatatgg ttttccatta
     3121 tctagatgtt tttggtcgtc cagaagatgc tcaagaaatt gctgatatga aagaacgtta
     3181 tcaacgaggt ggtcttggtg atgtgaagac caagcgttat ctacttgaaa tattagaacg
     3241 tgaactgggt cctattcgtg agcgccgtat tgaatttgct aaggatatgg gagaagttta
     3301 taatatgatt caaaaaggta gtgaaagagc gcgtgaagtt gcgggtcaaa ccctatctga
     3361 ggtaaaaggg gcaatgggac ttcattactt taactaagtt tattttacaa gaaactatca
     3421 tttctatctc gaagaaaaga tagtttttta tttacccctg taacatttga caaattttta
     3481 tagaatggta tgatagatac aatataaaaa gagtcaagct caaaaagaaa gaaaagagga
     3541 aacttcgaat gtctaattgg gacactaaat ttttgaaaaa aggttttacc tttgatgatg
     3601 tattgcttat tccagctgaa agtcatgtgt tgcctaacga tgcagattta acaactaaat
     3661 tggcagataa tttgacttta aatatcccaa ttattaccgc tgccatggac acagttacag
     3721 agagtcaaat ggccattgct attgctcgtg caggtggtct cggagttatc cataaaaaca
     3781 tgtcaattgc tcaacaagca gacgaggttc gtaaggtaaa acgttctgaa aatggagtta
     3841 ttattgatcc gttcttcttg acgcctgaac atacaattgc tgaagcagat gagcttatgg
     3901 gtcgttaccg catcagtggt gttccagttg ttgaaacact tgaaaatcgt aaattggttg
     3961 gtattttgac aaaccgagat cttcgtttta tttcagatta taatcaacca atttcaaacc
     4021 atatgactag tgaaaatctt gttactgctc ctgtgggtac ggatcttgca acggctgaga
     4081 gtattcttca agagcatcgt attgaaaaac ttccgttggt cgatgaagaa ggcagtcttt
     4141 ctggtttgat cactatcaaa gatattgaaa aagttattga gtttccaaat gcggctaaag
     4201 atgaatttgg tcgtcttcta gttgcaggtg cagtaggtgt tacttcagat acatttgaac
     4261 gtgcagaggc tctttttgag gcaggagcgg atgcgattgt tattgatact gcacatggtc
     4321 attctgcagg tgtcttgcgt aaaattgccg agattcgtgc tcatttccca gatcggactt
     4381 tgattgctgg aaatattgct actgctgaag gtgcacgtgc cctttatgaa gcgggtgtag
     4441 acgttgttaa ggttggtatt ggaccaggtt ctatctgtac tactcgtgtg attgctggtg
     4501 ttggtgttcc gcaagtaaca gctatctacg atgctgcagc tgttgcgcgc gaatatggta
     4561 aaacgattat tgctgacggt gggatcaagt attctggaga tattgtaaaa gcacttgctg
     4621 caggtggaaa tgctgttatg cttggatcta tgtttgctgg aactgatgaa gctccaggcg
     4681 aaactgaaat cttccaagga cgtaaattca agacttaccg tggtatggga tcaattgctg
     4741 ctatgaagaa aggttcaagc gaccgttatt tccaaggttc tgtcaatgaa gcaaacaagc
     4801 tcgttccaga aggaattgaa ggtcgtgttg cttataaagg agcggcagct gatattgttt
     4861 tccaaatgat tggtggtatt cgctctggta tgggttactg tggtgcagct aaccttaaag
     4921 aactacacga taatgctcaa tttattgaaa tgtctggtgc tggtttgaaa gaaagccatc
     4981 ctcatgatgt gcaaattact aatgaggcac caaattattc tatgtaaaaa acaatgaaaa
     5041 gaactccagt gaaaacagga gttcttttac aatgttgtca atttccattt acagaagctt
     5101 taccatcctg aatagtgaag atacttagat tttctggcag attttgaaga tggtctaagc
     5161 ttgttgttgt gataaaggtt tggattgatt gagaaatcgt ttctaataat tttaactgtc
     5221 tagtgttgtc aagttcactc atcacatcgt caagcagtaa tatcggagat tctgtggtaa
     5281 tgctttccat taattcgatt tctgctaatt ttatcgagag gacgagacta cgatgttgac
     5341 cttggcttcc gaaactagca tccatcccat ttatataaaa agaaatgtca tctcgatgag
     5401 gaccgacacc agtattcttt ttaaataaat ctctggatct acttttttct aaagcaattt
     5461 tgaaagattc ggataagttt tgtttgtcag ttatattgac agaagattga taggatattg
     5521 acaactcttc gatctgatta gagagttcaa aatgtttctt acgcccaaat gattctagtt
     5581 tttttatgaa atctaagcgg tgattcatta cacgacatcc ataatcaact agctgatcat
     5641 ctaacacaga aaggaatgtt tcatctattt tttgatctga ttttaggtaa gtgtttcttt
     5701 gctttaggat gtggttataa ttggttaagt cagataagta gattggctta atttgcccaa
     5761 gttccatatc aatgaatttt cgtcgaatcg aaggtgctcc tttaattagt tgtaaatctt
     5821 caggagcaaa taagacaaca ttcatgtgtc ctacataatc tgaaaggcgt gcctgtttta
     5881 agtgattaac ttttgttaca cggccttttt gtgttagttc gatttctagg ggaatggatc
     5941 cagttttttt ctgaacgaga cctgaaagat gaagttgttc ctcatcaaaa tgaatgagat
     6001 ttttatctgt tcgagttcga tgactacgcg ttaaggctaa aaaatagata gcctctaaca
     6061 tgtttgtttt tccttgtgca ttacgtccca aaaagacatt caatttagga ttaaagtcta
     6121 ttttcgtttc tttgtaatta cgaaaagtct tgagagatag atgttgtagc cacatgatta
     6181 tctaccaggg aatcgtggag cttgttggct tttaggtgat gaagcaggtt tcgatttgtc
     6241 ttttttaact cccttattca tctttttgac aagtttagcg atccgttctt tttcaacttt
     6301 atcagcttgg tattcatctt gttcttcaga agtaggttgt gtcaacaaga tgtcaatgtt
     6361 catgtcaggg atgtcaactt tatcgccaat acgaagtttt tttccacgac gactctctaa
     6421 ttccctatta aagtaaacag aatgttcaga gagaaatgat ttaatagctc ctccgctatg
     6481 tgtaattcca agttctttga gtagtgcttg gagggtaata aattcttcaa ataatttgta
     6541 ttccataatt cacctcaatc tttggtatta taccatattt tcctaaaaat agtgagagag
     6601 acagcgagaa atgtaagcga tttttatttc aaaagtgtta cagggaacaa gaaaatttca
     6661 ggttttcgtg atataataga agtctgtata taaggaggta aatcatggag ttagtgcatg
     6721 gaatttcaac acattttatc caatcaaaaa agtttaaaac aaacaaaatt accgtgcgtt
     6781 ttaccgctcc attatccctt gatacgattg caggtcacat gttgagtgca agtatgctag
     6841 agactgctaa tcagatgtac cctacttctc aagatttgag gagacacttg gccagtctat
     6901 acggtacaga tatgtcaacc aattgtttca gaagagggca aagccacatt atagaattga
     6961 catttaccta tgttcgtgat gagtttttaa gtaggaaaaa cgtgctaacc tctcagattt
     7021 tggaacttgt aaaagaaact cttttttcac ccgtagtagt tgataatggg tttgatccgg
     7081 ccttatttga aattgagaaa aaacaattgc tagcaagttt agcagctgat atggatgatt
     7141 ctttttattt tgcacataaa gaattggata aattgttttt tcatgatgaa cgtcttcaat
     7201 tggaatatag tgatttacga aatcgtattt tagatgaaac tccacaaagt tcttattctt
     7261 gtttccaaga atttttagcc aatgatcgaa tagatttctt tttcctaggt gattttaatg
     7321 aggttgaaat tcaaaatgta ttagaatcat ttggctttaa aggtcgaaaa ggagatgtga
     7381 aggttcagta ttgtcaacct tattctaata tccttcagga aggtatggtt cggaaaaatg
     7441 tgggacaatc cattttggaa ttaggttatc attaccgttc taaatatggt gatgaacaac
     7501 atttacccat gattgtaatg aatggtttac ttggtggatt tgctcactct aagctcttta
     7561 caaatgtccg tgaaaatgct ggattagctt ataccatttc aagtgagctt gatttattta
     7621 gtggattctt gaggatgtat gctggtatca atcgagaaaa tcgtaaccag gctcgtaaaa
     7681 tgatgaataa tcaactgctt gatttaaaaa aaggttattt tacagagttt gagttaaatc
     7741 agaccaagga aatgattcgt tggtcgttgt tactttctca agataatcaa tcttcattga
     7801 ttgaacgtgc ttatcaaaat gccttatttg gaaaatcttc agcagacttt aaaagttgga
     7861 ttgcaaagct tgaacaaatt gacaaagatg ctatttgtag agtagctaat aatgtgaaac
     7921 tacaagcgat ttactttatg gaaggaatag aatgacaaag gttgtttttg aagaaaaata
     7981 ctatccagct gtaaaagaaa tggtttatcg aactcgtttg gccaacggat tgacagttgc
     8041 tcttttgcct aaaaaggaat ttaaagaggt ttacgggagt gtcactgtac agtttggttc
     8101 ggtagatacg tttgtcacag aagttgacgg agatgtaaaa caatatcctg gaggaattgc
     8161 tcattttctt gaacataaat tatttgagag agaagattct agtgatttga tgtcggcttt
     8221 tacgaatcta ggtgcagata gcaatgcctt tacaagcttt acaaaaacaa actatctttt
     8281 ttcagcaacg gattattttt tagaaaattt agatttactt gatgaattgg taacatcagc
     8341 acactttact gaagcttcca ttctgacaga gcaggatatt attcagcaag aacgagaaat
     8401 gtaccaagat gatccagatt cgtgtttatt cttttcaact ttagcgaatt tgtatcctgg
     8461 tacaccttta gcaactgata tagttggaag tgaggagtcc atttcccaaa tcaatctaac
     8521 taatttgcaa gaaaatttta caaagtttta caaacctgta aacatgtctc tgtttttagt
     8581 tggtaatttt gatgtggagc gagtacagga ctattttgaa agcaaagaac tgaaagattc
     8641 agattttcag gaagtagcaa gagaaaagtt gtttttacag cctgtaaagc taacagatag
     8701 tatgagaatg gaagtatctt ctcccaaact agcgattgga gttagaggta agcgagaagt
     8761 ttctgaagcg gattgctatc gacatcatat tttattaaaa ttattgtttg caatgatgtt
     8821 tggttggact tcggatcgtt ttcaaaaatg ttatgaatca ggtaaaattg atgcgtcctt
     8881 atctctggaa gttgaaataa caagtcgctt tcattttgtc atgttgacaa tggatacgaa
     8941 agagccagtt gctttgtctc atcaatttag gaaggctatt cgtaatttta caaaggattt
     9001 agatattaca gaggaacatt tagatattat caaaagagag atgtttggcg aatttttcag
     9061 tagcatgaac tctcttgaat ttattgcaac gcaatatgat gcttttgaaa atggtgagac
     9121 aatttttgat ttgccgaaaa ttttacagga aattacttta gaggatgtcc ttgatgctgg
     9181 acatcattta atagatgatg gtgacatagt tgattttaca atattcccat cgtagtaacc
     9241 tatcataata gacactagaa agaagagatg acaagtatga gaaaaaaaac aattggagag
     9301 gttttacgat tagctagaat caatcaggga ttgagtttag atgaattgca gaaaaagaca
     9361 gaaatccagt tagatatgtt ggaagcaatg gaagcagacg atttcgatca acttccaagt
     9421 cctttttaca cgcgttcttt cttgaaaaaa tatgcatggg ctgttgagtt agatgaccaa
     9481 attgttttgg atgcttatga ttctgggagt atgattactt atgaggaagt agatgttgat
     9541 gaagatgagt tgacaggtcg tagacgttca agtaagaaaa agaagaaaaa aacatcattt
     9601 ttacctttat tttattttat cctttttgct ttatcgattt taatttttgt gacttattat
     9661 gtttggaact atattcaaac tcaaccagag gagccttctc tttctaatta cagtgtggtt
     9721 caatcaacaa gttcaactag ctctgttccc cactcctcaa gtagtagttc ttctagtata
     9781 gaatcagcta taagtgtatc aggcgaagga aatcatgtag aaatcgctta taagacaagt
     9841 aaggaaacag ttaaattgca attggcagtt tcagatgtta caagttgggt cagtgtttca
     9901 gaaagcgaac ttgagggcgg tgtaacctta tcgccaaaga agaaaagtgc agaagcaaca
     9961 gttgcaacta aaagtcctgt aacaattacg ttaggtgttg taaaaggtgt tgatttgaca
    10021 gtagataatc agactgttga tttatcgaaa ttaacagctc agactggaca aatcactgta
    10081 acctttacta aaaattaagg aaaaacgaat gaaaaaagaa caaattccca atctcttaac
    10141 aataggtcga attctcttta tacctatttt tatctttatt ttaacgatag gaaattcgat
    10201 agagagtcat atagttgcag ctattatctt tgctgttgcc agtattaccg actatttaga
    10261 tggatattta gctcgtaaat ggaatgtggt cagtaatttt ggtaaatttg cagatcctat
    10321 ggcggataag ttactagtta tgtcggcttt tattatgttg attgagttag gtatggctcc
    10381 ggcttggatt gttgcagtga ttatctgtcg tgagttagct gtgacaggtt taaggctttt
    10441 attggttgaa actggtggaa caattttagc agcagcaata cctggaaaaa ttaaaacttt
    10501 tagtcagatg tttgctatta ttttcttgct attacattgg actttgcttg gtcaagttct
    10561 actttatgta gccttatttt tcactatcta ctctggctat gactatttca agggtagtgc
    10621 ctatgtattt aaagggacat ttggttcgaa atgaaatcaa taattgatgt aaaaaatctt
    10681 tcttttcgct ataaagaaaa tcagaactac tacgatgtga aggatattac gtttcacgtg
    10741 aaacgtggag aatggctttc gattgtaggg cataatggta gtggtaaatc aacgacggtt
    10801 cgattaattg atggcttact ggaagcagaa tccggagaga ttgtaattga tggccaacgt
    10861 ttgactgagg aaaatgtttg gaatatacgt cgtcaaatcg gtatggtttt tcaaaatcca
    10921 gacaatcaat ttgttggagc gactgttgaa gatgatgttg cttttggttt ggaaaatcag
    10981 ggactttctc gtcaagaaat gaaaaagaga gtggaagaag ctctggcttt agttggcatg
    11041 ttggacttta aaaagagaga gccagcgcgt ctatcaggtg gccaaaagca acgtgtggcc
    11101 attgcaggtg ttgtagccct aagaccagct attttaatct tagatgaagc aacgagtatg
    11161 ttggatcctg aggggcgtag agaacttatt gggacagtaa aaggaattcg aaaagactat
    11221 gatatgacgg tcatttctat tacccatgat ttggaagaag tcgccatgag tgatcgcgta
    11281 ttggtcatga aaaaagggga aattgaatca actagtagtc caagggagct tttctctcga
    11341 aatgatttag atcaaattgg attagacgat ccttttgcta atcaattaaa aaaatctttg
    11401 agccagaatg gctatgattt acctgaaaat tatttgacag aaagtgagct agaggataag
    11461 ctatgggaat tgctctagaa aatgtgaatt ttacatatca agaaggtact cccttagctt
    11521 cagcagcttt gtcggatgtt tctttgacga ttgaagatgg ctcttataca gctttaattg
    11581 ggcacacagg tagtggtaaa tcaactattt tacaactctt aaatggttta ttggtgccaa
    11641 gtcaagggag tgtgagggtt tttgatacct taatcacctc gacttctaaa aataaagata
    11701 ttcgtcaaat tagaaaacag gttggcttgg tatttcagtt tgctgaaaat cagatttttg
    11761 aagaaacggt tttgaaggac gttgcttttg gaccgcaaaa ttttggagtt tctgaagaag
    11821 atgctgtgaa gactgcgcgt gagaaactgg ctctggttgg aattgatgaa tcactttttg
    11881 atcgtagtcc gtttgagctg tcagggggac aaatgagacg tgttgccatt gcaggcatac
    11941 ttgccatgga gccagctata ttagtcttag atgagccaac agctggtcta gatcctctag
    12001 ggagaaaaga gttgatgacc ctgttcaaaa aactccacca gtcagggatg accatcgtct
    12061 tggtaacgca tttgatggat gatgttgctg aatatgcgaa tcaagtctat gtaatggaaa
    12121 agggacgttt agtaaagggg ggcaaaccaa gtgatgtctt tcaagacgtt gtttttatgg
    12181 aagaagttca gttgggagta cctaaaatta cggccttttg taaacgattg gctgatagag
    12241 gcgtgtcatt taaacgatta ccgattaaga tagaggagtt caaggagtcg ctaaatggat
    12301 agtatgattt tggggcgtta tatcccaggg gattcgattg ttcaccgatt ggatccacgt
    12361 agcaaattgc ttgctatgat gctactgatt ttgattgtgt tttgggctaa taaccccttg
    12421 acgaatctga ttctttttat agcgacaggg atatttattg ccttgtcagg agtatctctt
    12481 tcatttttta ttcagggctt gaagtctatg tttttcttga ttgccttcac aactattttt
    12541 caactatttt tcatttctaa tgggaatgtt ttatttgagt tttcgtttgt gagaatcacg
    12601 gattatgctt tgcaacaagc tgggattatt ttttgtcgct ttgtattgat tattttcttt
    12661 tcaactttgt taaccttaac aaccatgcct ttaagtttgg catcagctgt cgaagcttta
    12721 ttagcacctt taaagcgtgt gaaagttcca gttcatgaaa ttggattgat gctgtctatg
    12781 agtttgcgtt ttgtcccaac cttgatggat gatacgactc ggattatgaa tgcacagaaa
    12841 gctcgtggag tggattttgg agaaggaagc atcgttcaaa aagtaaaggc gatgattccc
    12901 attttgattc ctctttttgc gacaagttta aaacgtgcag attccttggc tatcgctatg
    12961 gaagcgcgtg gctatcaggg tggaaaaggc agaattcaat accgacaatt gaaatggact
    13021 ctaaaggata cgctgaccat tcttgttatt ctcgtacttg gttgttgttt atttttctta
    13081 aaatcttagt agctttcagg aattgataaa aagttactgt aacagttttt gatagaaagg
    13141 tagggatatg aaccgtttta aaaaatcaaa atatgtcatt attgtttttg tcactgttct
    13201 gcttgtgtca gctctcttag cgacgactta ttcaagtaca attgtgacaa aattaggaga
    13261 tggaatctca ttggttgata gagttgtaca aaaacctttt cagtggtttg attctgtcaa
    13321 atcagatttg gctcatttga cacgaacata taatgaaaat gaaagtttga agaaacagct
    13381 ttaccaatta gaagttaaat caaatgaggt ggaaagttta aagacagaaa atgaacaact
    13441 gcgccaattg cttgatatga agtctaaatt gcaagccaca aagactttag cagcagatgt
    13501 tattatgcgt tctccggtat cttggaagca ggagttgacc ttagatgcag gtagatcaaa
    13561 aggtgcttct gagaacatgt tagctattgc aaatggtggc ttgattggga gtgtttcaaa
    13621 agtagaggag aactctacta tagtcaacct tctgacaaat acggaaaatg ctgataagat
    13681 ttctgttaaa attcaacatg gctctactac aatttatgga attattattg gctatgacaa
    13741 ggaaaatgac gttcttaaaa ttagccaatt aaatagtaat agcgatatta gtgcgggaga
    13801 taaggtgact actggtggat taggaaactt taacgttgct gatattcctg ttggtgaagt
    13861 ggttgccaca acgcatagta cagactattt gacacgagaa gtaactgtta aattgagtgc
    13921 agatactcat aatgtagatg tgatagaatt agtggggaat tcataatgag acagttgaag
    13981 cgagttggag tatttttatt gcttcctttc tttgttctaa ttgacgccca tattagccag
    14041 cttctgggct catttttccc ccatgtacat ttggctagtc attttctttt tctatttctc
    14101 ttatttgaga cgatagaagt atcagagtat ctctacctag tctattgttt tgttataggc
    14161 ttggtttatg atgtttactt tttccatcta atagggatta caactctctt atttatctta
    14221 ttgggagcct tccttcataa attgaatagt gttattttgt tgaatcgttg gacaagaatg
    14281 ctagctatga ttgtgctgac attcctgttt gaaatgggta gttatctttt ggcttttatg
    14341 gtagggttga cagtagatag catgtcgatt tttatagtct atagcttggt accgacgatg
    14401 attttaaatt ttttatggat tactgttttt caatttattt ttgaaaaata ttatctataa
    14461 gaacgacata taaatgtaac aaaggcgtaa tatttattag gccttttttt ggtatactag
    14521 tattgtcttt aaaagaagga gtatctacgt aatatgaaga aaaaaatctt agcgtcactt
    14581 ttattaagta cagtaatggt ttctcaagta gctgttttaa caactgcgca tgcagaaacg
    14641 actgatgaca aaattgctgc tcaagataat aaaattagta acttaacagc acaacaacaa
    14701 gaagcccaaa aacaagttga ccaaattcag gagcaagtat cagctattca agctgagcag
    14761 tctaacttgc aagctgaaaa tgatagatta caagcagaat ctaagaaact cgagggtgag
    14821 attacagaac tttctaaaaa cattgtttct cgtaaccaat cgttggaaaa acaagctcgt
    14881 agtgctcaaa caaatggagc cgtaactagc tatatcaata ccattgtaaa ctcaaaatca
    14941 attacagaag ctatttcacg tgttgctgca atgagtgaaa tcgtatctgc aaacaacaaa
    15001 atgttagaac aacaaaaggc agataaaaaa gctatttctg aaaaacaagt agcaaataat
    15061 gatgctatca atactgtaat tgctaatcaa caaaaattgg ctgatgatgc tcaagcgttg
    15121 actacgaaac aggcagaact aaaagctgct gaattaagtc ttgctgctga gaaagcgaca
    15181 gctgaagggg aaaaagcaag tctattagag caaaaagcag cagctgaggc agaggctcgt
    15241 gcagctgcgg tagcagaagc agcttataaa gaaaaacgag ctagccaaca acaatcagta
    15301 cttgcttcag caaacactaa cttaacagct caagtgcaag cagtatctga atctgcagca
    15361 gcacctgtcc gtgcaaaagt tcgtccaaca tacagtacaa acgcttcaag ttatccaatt
    15421 ggagaatgta catggggagt aaaaacattg gcaccttggg ctggagacta ctggggtaat
    15481 ggagcacagt gggctacaag tgcagcagca gcaggtttcc gtacaggttc aacacctcaa
    15541 gttggagcaa ttgcatgttg gaatgatggt ggatatggtc acgtagcggt tgttacagct
    15601 gttgaatcaa caacacgtat ccaagtatca gaatcaaatt atgcaggtaa tcgtacaatt
    15661 ggaaatcacc gtggatggtt caatccaaca acaacttctg aaggttttgt tacatatatt
    15721 tatgcagatt aatttacaga gggactcgaa tagagccctc ttttcaggtt ttaccgtgac
    15781 aatccctatt aaaaattata tcaaaatagc ttgaaaatat tggaaaagta tggtaaaatg
    15841 aaaattgtcg tgtgaacgat aatactcatt cttgatgaat tgtgaagcag ttgcccttgg
    15901 gtcgttttgc gagttgaagt caagaagagg aaaaaaacaa aaaggagaaa tactcatggc
    15961 agtaatttca atgaaacaac ttcttgaggc tggtgtacac tttggtcacc aaactcgtcg
    16021 ctggaatcct aagatggcta agtacatctt tactgaacgt aacggaatcc acgttatcga
    16081 cttgcaacaa actgtaaaat acgctgacca agcatacgac ttcatgcgtg atgcagcagc
    16141 taacgatgca gttgtattgt tcgttggtac taagaaacaa gcagctgatg cagttgctga
    16201 agaagcagta cgttcaggtc aatacttcat caaccaccgt tggttgggtg gaactcttac
    16261 aaactgggga acaatccaaa aacgtatcgc tcgtttgaaa gaaattaaac gtatggaaga
    16321 agatggaact ttcgaagttc ttcctaagaa agaagttgca cttcttaaca aacaacgtgc
    16381 gcgtcttgaa aaattcttgg gtggtatcga agatatgcct cgtatcccag atgtgatgta
    16441 cgtagttgac ccacataaag agcaaatcgc tgttaaagaa gctaaaaaat tgggaatccc
    16501 agttgtagcg atggttgaca ccaatactga tccagatgat atcgatgtaa tcatcccagc
    16561 taacgatgac gctatccgtg ctgttaaatt gatcacagct aaattggctg acgctattat
    16621 cgaaggacgt caaggtgagg atgcagtagc agttgaagca gaatttgcag cttcagaaac
    16681 tcaagcagat tcaattgaag aaatcgttga agttgtagaa ggcgacaacg cttaatttat
    16741 acaaatagta attacctagg agggcggggc ttagcccggc tctcctattt tcaaaaaatg
    16801 taggagaatt aaaatggcag aaattacagc taaacttgta aaagagttgc gtgaaaaatc
    16861 tggtgccggt gttatggacg ctaaaaaagc gcttgtagaa acagacggtg acatcgaaaa
    16921 agcgattgaa ttgcttcgtg aaaaaggtat ggctaaggca gctaagaaag ctgaccgtgt
    16981 tgctgcagaa ggtttgactg gtgtttatgt taacggtaat gttgcagcag ttattgaagt
    17041 aaacgctgaa actgacttcg ttgcaaaaaa cgctcaattc gttgaattgg taaatactac
    17101 agcgaaagtc attgctgaag gaaaacctgc taacaacgaa gaagctcttg ctttgataat
    17161 gccttcaggt gaaactcttg aagctgcata cgtatctgca acagcaacta tcggagagaa
    17221 aatctcattc cgtcgctttg cattgattga aaaaacagac gcacaacact ttggagcata
    17281 ccaacataac ggtggacgta tcggtgttat ttcagttgtt gaagatggag acgaagcact
    17341 tgctaaacaa ttgtcaatgc acatcgcagc gatgaaacca acagttcttt cttacaaaga
    17401 attggatgag caattcgtta aagatgagtt ggcacaattg aatcacgtta tcgaccaaga
    17461 caacgaaagc cgtgcaatgg ttaataaacc agctcttcca cacttgaagt atggatcaaa
    17521 agctcaatta actgatgatg ttattgctca agctgaagct gacatcaaag ctgaattggc
    17581 tgcagaaggc aaaccagaaa aaatctggga caaaattatt ccaggtaaaa tggatcgctt
    17641 catgcttgat aacactaaag ttgaccaagc ttacacactt cttgcacaag tttatatcat
    17701 ggatgacagc aagacagttg aagcatacct tgaatcagtt aacgcttcgg tagttgagtt
    17761 tgctcgcttt gaagttggtg aaggtatcga gaaagctgca aacgacttcg aagctgaagt
    17821 tgcagctaca atggcagcag ccttgaataa ctaataatag aaaggaagca aattgcttcc
    17881 ttttttgtat agggcttaga tttttcctga aattgttttt tccccagtct cactcgatta
    17941 gaataattaa aacaaaaagc cctataataa gggctaagtg catttaggag actatacttc
    18001 aaattcatag taagcgcgtc ataacaaggt atctatccta attccccaac ttccagtata
    18061 ctagataaaa aataattatc ggaggaaagg tattgtacta tgataattca actaagtgat
    18121 ttaggtcaag ttcaccttgt ttgtggcaag acagatatga gg
//
LOCUS       DAVHSI010000041        16359 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.042, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000041 DAVHSI010000000
VERSION     DAVHSI010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16359
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.042"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(59..538)
                     /locus_tag="VVR21_001675"
     CDS             complement(59..538)
                     /locus_tag="VVR21_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6055495.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            complement(660..1196)
                     /gene="nusG"
                     /locus_tag="VVR21_001676"
     CDS             complement(660..1196)
                     /gene="nusG"
                     /locus_tag="VVR21_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU6055496.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            complement(1251..1427)
                     /gene="secE"
                     /locus_tag="VVR21_001677"
     CDS             complement(1251..1427)
                     /gene="secE"
                     /locus_tag="VVR21_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU6055497.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            complement(1437..1589)
                     /gene="rpmG"
                     /locus_tag="VVR21_001678"
     CDS             complement(1437..1589)
                     /gene="rpmG"
                     /locus_tag="VVR21_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU6055498.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            complement(1642..3837)
                     /locus_tag="VVR21_001679"
     CDS             complement(1642..3837)
                     /locus_tag="VVR21_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU6055499.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            3963..4799
                     /locus_tag="VVR21_001680"
     CDS             3963..4799
                     /locus_tag="VVR21_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU6055500.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            complement(4867..5874)
                     /gene="gap"
                     /locus_tag="VVR21_001681"
     CDS             complement(4867..5874)
                     /gene="gap"
                     /locus_tag="VVR21_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU6055501.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6051..7013)
                     /locus_tag="VVR21_001682"
     CDS             complement(6051..7013)
                     /locus_tag="VVR21_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU6055502.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFMKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            complement(7074..7924)
                     /locus_tag="VVR21_001683"
                     /pseudo
     CDS             complement(7074..7924)
                     /locus_tag="VVR21_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(8055..8927)
                     /locus_tag="VVR21_001684"
     CDS             complement(8055..8927)
                     /locus_tag="VVR21_001684"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU6055503.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            9164..10474
                     /locus_tag="VVR21_001685"
     CDS             9164..10474
                     /locus_tag="VVR21_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU6055504.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(10840..11034)
                     /locus_tag="VVR21_001686"
     CDS             complement(10840..11034)
                     /locus_tag="VVR21_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6055505.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     LSSGVTLITGKNGTGKSTLL"
     gene            complement(11495..12223)
                     /locus_tag="VVR21_001687"
     CDS             complement(11495..12223)
                     /locus_tag="VVR21_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU6055506.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            12381..13790
                     /locus_tag="VVR21_001688"
     CDS             12381..13790
                     /locus_tag="VVR21_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU6055507.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENAMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            13808..15103
                     /locus_tag="VVR21_001689"
     CDS             13808..15103
                     /locus_tag="VVR21_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6055508.1"
                     /translation="MKNSKFIDQFAIFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            15108..15416
                     /locus_tag="VVR21_001690"
     CDS             15108..15416
                     /locus_tag="VVR21_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6055509.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            15413..15721
                     /locus_tag="VVR21_001691"
     CDS             15413..15721
                     /locus_tag="VVR21_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6055510.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         5057 a         3303 c         2836 g         5163 t
ORIGIN      
        1 cttttcaaac tttgtcaact actttttcta atttttttca ttttttttgc atgacttact
       61 aatgggtacg gatagtaaac tccttaaaca caatgcgtaa gtctcttaat actctttgac
      121 gccctcgaaa tcgttcattg cttaagacgc gttctagttc ttcttgtttc tctttacttt
      181 gtttgtttct ataatctctt agtgtttcat gaaagagata ataatcatct agccagagac
      241 ccccctcact tatacgatga ctgatctcac ccacttcttc atagggttct ttatcgtatc
      301 tacgcttctg actttcctgc ttacggatat agtctaaaat tcgatttcga aacttggttt
      361 tgaaatattt ccttaaacgt ggaatatcgt ctaccagtcc ttcttctcta ctaatcaatt
      421 catgtaagca gagcatgcct tcttggtccc aatccgacaa ttcccataaa tgaaggtaat
      481 attcatttct acacttatac acagtccctt ggacttcttc atacaattct ttaatcataa
      541 ttttcccctt tctagataca gtctaacaga ttagaaaaca catttgttcc attttctcca
      601 ttctgttccc tttagctcct aaactgcaca aaaaagagag gctccagcct ctctcagggt
      661 tataattctg cgatttggtt taggtttact tctgcaactg tgtcattacc aaacatagag
      721 ataatcattt tcactttgtt attatcaatt tctgtaatct taccagtgta gtctgcaaaa
      781 gcaccatcaa taatacgtac agtttgacca atctcaacat cgaaatcaaa ttcttgaaca
      841 gtttgtccca tagataccaa aatgtcacga atttcttgtt ccaataatgg agttggtttt
      901 gatctgttcc cgtgtgatcc gacaaatcct gtaacatttg gtgtgtttcg aacaacaaac
      961 caagcttcat ctgtcatgac catttctaca agaacataac ctggaaagcg attttcttct
     1021 acttcttttc tctttccatt tttttcaact tgcactgttt gtgttggaat ttcaacgcgt
     1081 agaatattat ccaacatatt gtaggtttgt gcacgttgta atagattttc tttcacctta
     1141 ttttcataac cagaataagt ttgtaaaaca aaccatcctt tatcaaaact atccatgata
     1201 tttcctttca taaatagaag atttctagtg taattaactc cactaatctt ctaaaaaatg
     1261 ttaataaatc gaatcaaacc tgaaacaatc aactggtcaa aaatgtaaat aattactaca
     1321 aagaaagctg tgtattccat gatagaacga aaatctctcc agctttcctt gcgagttggc
     1381 catgttgtgt ctttaagaag tctaaaaata tctccaataa aacgcatcgc tctctcctat
     1441 ctcgtttctc tgtgtgtagt gtacttgcca caatgcttac aaaatttatt tacttctagt
     1501 cgtgtaggct tggggtttcc gctgatcttg attgaatagt ttctcgaacc acaaaccgca
     1561 caagctaggc ttgctttttt tagtgccata acgcctccat cttatccatt ataacaagaa
     1621 agctaggctt tgacaagcat cttagcgaaa tagattgact atcgaatccc atattgtttg
     1681 agccttttcc ttaatcttcg catctgagat agcccggcta gcctcatcta ctagactttg
     1741 cgcacgccct cgaatatcag acaaattatc atctgtctgg ctattatcat tggtttgtac
     1801 ttgtcttttt gtattggctg gtgcaattcc attttgctta taagcatttt caaccgtaaa
     1861 ggtacttcct ggcgtataag gtaaaatggt attggcaatg tttctaaaga catgagctgc
     1921 accgtttgaa gtagagccag ctagatagtg gttttcatca gtggtcggaa agccaagcca
     1981 gtggctaatc actacatccg gagtataacc aattacccac tggtcacttg tgtactccgg
     2041 attgaaaact gcttcagttg ttccagtttt ccctgccatg acatagtctg caggcgatga
     2101 actaataccg gtaccgttgg tgaaagtccc caacatcata ctggtcatct tgtcagctac
     2161 agacttatca atcacccgtt tttgtgaatt tttatgactc gcaataactt gtccactagc
     2221 attttcaatt ctactaataa aatgagcttc aggcattaaa ccttcatttg caaaggcggc
     2281 gtatgcttga gccatttgaa gagggttggt ttcaacaccg cttcccaagg cgacaccaag
     2341 aacacggtcg accttttcca tgttgagtcc gaatttttcg cctgcctcaa aagccttgtc
     2401 gacacccaaa tcattaacag tggcaacagc aggtagatta agcgattctg ccaaggcttg
     2461 atacatagga acttctcgac tcgttttgat ccctgcatag ttatcaacct tatagctgtc
     2521 atactgcatg gtatggttat ccaactgctt attcaaagcc cagcctgctt caactgctgg
     2581 cgtataaaca actaaaggct taattgtaga accaggacta cgctttgatt gggttgcata
     2641 gttgaaattc cggaatccag ttttatcatt gtcagcaact tgaccgacaa ctccacgaac
     2701 tccccctgtt ttcggttcga gagctacact tcctgattga gcaaacgttc catcctctgc
     2761 cctcggaaat agcgatgtgt tttcataaac aatctgcata tttgcttggt agttttggtc
     2821 cagctctgtg taaatgcggt agccattatt gacaatctct tcctctgtta gattatactt
     2881 ggaaacagct tcattaacca ccgcatcaaa ataagagggg taacggtaat ctgagatttt
     2941 tccttcatac ttatcgtgca attgcgaagt catatcaact tcagcagctt cggtttcttg
     3001 gtttttatca atatatcctg ctgcaaccat attcttcaag acagtatcgc gccgattagt
     3061 agaatcttct acggaattca agggattata cagttccggc cccttgagca tccctgccag
     3121 agtcgcagct tgatccagac tcacttctga tgcagaaact ccaaagtatt tcttactcgc
     3181 atcttctaca ccccacacac catttccaaa ataagcgttg ttaaggtaca tggttagaat
     3241 ttgctcctta ctatattttt tgcttaattc taaggcaagg aaaaattctt tcgcttttct
     3301 ctcaacagtt tgatcctgcg ataaataggc gtttttagcc agctgttggg taatggtaga
     3361 gccaccacct gaacgtccag cagtgacaat agccaagaag aaacggccat agttaatccc
     3421 gtcattttta tagaaagaac ggtcttctgt cgcaataaca gcattctgca agtttttact
     3481 gatgtcagtc agctcaacat aggttccctt ttgaccagac aaggcaccag cctctttttc
     3541 ttcacggtca aaaataagag tccgagtttt caaggcattt tgcaaatcat tgacattggt
     3601 cgacttggct acagcaaaca aatagattcc aactagcaag cctgcactca aacctagtat
     3661 aaggataatc tttgttagat gataacgacg ccagaatttt cgaatcggac ctacttgggc
     3721 taattttttt cgatcactac gagagcgacg taagatagta gaatcagagt cctctagttc
     3781 acttgtttct tttttaaaaa gagaaagaaa tttctcaaat aatttatcta atttcatgcg
     3841 tttattttat catcttcatc ataggaagac aagaatttag ctatttccta tccaaatagg
     3901 gctttttttg ttacaatatc tgtatgcaat tcacatttac attacccgcc tctctacctc
     3961 aaatgacggt aaagcaatta cttgaggaac aactcctcat ccctagaaaa atccgtcatt
     4021 ttttgagaat caagaaacat attttgataa atcaagaaga agtccactgg aacgaaatcg
     4081 taaatcctgg agatgtttgc cagttgactt ttgacgagga agattattcc caaaagacga
     4141 tcccttgggg caacccagac ttagtgcagg aagtttatca agatcaacac ttgattattg
     4201 taaacaaacc agaggggatg aaaacgcatg gtaatcaacc aaacgaaatt gcccttctta
     4261 accatgtcag tacctatgtt ggccaaacct gctatgtcgt tcatcgtctg gacatggaaa
     4321 ccagtggctt agttctcttt gccaaaaatc cttttatcct gcccattctc aatcgcttat
     4381 tggagaaaaa agagatttct agagaatatt gggctctagt tgatggaaat atcaacagaa
     4441 aagaacttgt tttcagagac aaaattggac gtgatcgcca tgatcgtaga aaaagaatag
     4501 ttgatgcaaa aaatgggcaa tatgctgaaa cgcatgtaag cagattaaag caattctcaa
     4561 acaagacttc cttggctcat tgcaagctaa agacagggcg aacccatcag attcgtgtgc
     4621 accttttgca tcataatctt cctatcctgg gagaccctct ctataatagt aaatcaaaga
     4681 caagccggct tatgcttcat gccttccgac tttcctttac ccacccactt actttagaga
     4741 ggctaacttt cactaccctt tcaaatacat ttgaaaaaga attaaaaaag aatggatgat
     4801 cgtgtcatcc atttttccat ataaaaaagc aagaccacaa agccttgctt tctatcaact
     4861 caagaattat ttagcaatct ttgcgaagta ttcaagagta cgaacaagtt gtgcagtgta
     4921 tgacatttcg ttgtcgtacc atgatacaac tttaaccaat tgtttaccgt caacgtcaag
     4981 aactttagtt tgagttgcgt caaacaatga accgtaagac atacctacga tatctgaaga
     5041 tacgattgga tcttctgtgt aaccgtatga ttcgtttgaa gctgctttca tagctgcgtt
     5101 cacttcatca acagtaacgt tcttttcaag aactgctacc aattcagtaa ctgatccagt
     5161 tggagttgga acgcgttgtg cagatccgtc aagtttacca ttcaattctg gaattacaag
     5221 accgatagct tttgcagcac cagttgagtt aggaacgatg tttgcagcac cagcgcgagc
     5281 acggcgaagg tcaccaccac ggtgtggtcc gtcaaggatc atttggtcac cagtgtaagc
     5341 gtggatagta gtcatcaatc cttcaacaac accaaagttg tcttgaagag ctttagccat
     5401 tggagccaag cagtttgtag tacatgaagc acctgagata actgtttcag taccgtcaag
     5461 aacgttgtgg ttagtgttga atacaactgt tttaacgtcg tttccaccag gagcagtgat
     5521 aacaactttt ttagctccac ctttaaggtg tttttcagct gcttctttct tagcaaagaa
     5581 accagtagct tcaagaacga tttctacacc gtcagtagcc cagtcgattt gttctggatc
     5641 acgttcagca gaaactttga tgaatttacc gttaacttca aatccacctt ctttaacttc
     5701 aacagtaccg tcgaaacgac cttgagttgt gtcgtatttc aacaagtgtg caagcataac
     5761 tggatctgta aggtcgttga tgcgtgtaac ttcaacacct tctacgtttt ggatacgacg
     5821 gaaagcaaga cgaccgatac gtccgaaacc gttaatacca actttaacta ccattagtga
     5881 tttcctcctt atgaaaatca tgaaattttt attgtgaaaa gagtaacttg aatcactaca
     5941 aatcaccttt caacaaacct attatacaac tatttgagtt gaattgcaag tatggccatt
     6001 gtttttctat gttagtttct ttttaagact gtaaatcaag gaatccctta ctattcatag
     6061 cgtaacgatt ctacaggatc cattttacta atcttacgcg ccgggaagta ggctgagaca
     6121 taaccaagta atagagcgaa aactagagtt cctaaaacag ataaaagatt taattcaaaa
     6181 accttagtga tggatgggta aaagtgactt acaatcgcat tcgccaaact tcccacccct
     6241 tgtgcaacca aaaatgccag cagcaaggcg atgcctacaa tccagatagc ctcgtaaata
     6301 aaaattcctt tgacatcacg attctgataa ccaactgctt tcatgacacc tatttccttg
     6361 gaacgttgca tgatattgat gtaaataata ataccaatca taaccgctgc taccacaata
     6421 gcttgtgatg aaagcacaat caataatccc tgaataacac gaataaaggt aatcacaata
     6481 tcaagaactc tctgttgaga aagcacagta tacttcttat ttttctgtaa ttcttctgtt
     6541 actacttttg tctgtgatgg atctttgagt tccaagataa aataagatac agctttcata
     6601 aatccagcct ctttcaaaat cgtttccatt tgatgagaca gcatgaaact gttgctgtcc
     6661 tccatgtcat cttcatcatt gattacacgt acaatcttcg tttgaaattg agcaatctta
     6721 ctagcttcgg cagcactttc tacaatgctg gctgagactg atttgccaat aagatcatta
     6781 gctgtcaaat tttttcctgt ctgttcattc caatttttta gtaaactgct tggaatcgtt
     6841 aatccctgtt catttgtatc agtatagagg gatccagcca acactttgtc cgtctcatta
     6901 ctactaacag agatgcttgt atcctcataa agactcacta cttgagcata agaaggcatc
     6961 gtttgactca gatccatttc ttgcccatct atagtaatat ttgacatgtt catcccaaaa
     7021 ggactctcca aatgtttaat agcttctttc ccaactgtat ccgtgaacta tagtcaattg
     7081 aaacaagaac aagacaaaag agcctcataa aaggtattgc aacttggtaa tacccttttg
     7141 aggtgctttt tgatatgagc ccatgttttc tcaataggat tgtactcagg tgagtaggga
     7201 ggaagaggta aaagtttatg cccaaactcc tcgcataaaa gttctaactt acccattcta
     7261 tggaatcttg cattatccat aataataacc gatggtgtgg ttaatgttgg taagagaaac
     7321 ttctgaaacc aagcttcaaa aaagtcgctc gtcatcgtct cttcgtaagt cattggagcg
     7381 attaactcac cattcatttg ttagacctgc aaccaaagaa atcctctgat atcttcttcc
     7441 agatacttta cctcttatta actgaccttt taatgagcga ccatattctc gataaaaata
     7501 agtatcgaat cctgtttcat caatctaaac aggtgctagg tgctttaaac tattaaaatt
     7561 tttaagaaat aaggctactt tttctgggtc ttgttcatag taggtgtggt tctttttttc
     7621 gagtgtagcc catagctttg agcgcatagt ggatggtagt tggatgacag ccaaattcag
     7681 aagctatttc agtcaaataa gcgtctggat tgtcagtaag atagttttta agtctatctc
     7741 tatcaacctt tcttggtttt gttcctttta cttggtggtt tagctctcct gttttctctt
     7801 ttagctttaa ccagccataa atggtattac gtgagatttg gaaaacgtgt gatgcttctg
     7861 ttatactacc tgttcgctca caataagaga gaactttttt acgaaaatct attgaatatg
     7921 ccataagaag attataccac attgtgtact atttttggtt cattttacta tatttgaaga
     7981 ggcgtttaaa ctatctgaca taaaactcgt tctagaggaa agacatcctt taaaaagtta
     8041 gtttatttta caacttagac atcaaggtag gttaaaccct tcatggaaaa atcaagactc
     8101 ttagcactat gggttaaact accactggag acgtaatcaa tcgctaaacc acgaaaacgg
     8161 ctaatagtgg tcatatcaat atttccagaa cattcaatcc gagaacgtcc tgcaattagg
     8221 gtaatggcct gttcaatctg ttccaatgac atattatcca acatgataat atcagcaccc
     8281 gccgccgcag cttcttcggc agcagcaagg ctttccactt ccacctcgac cattttcaca
     8341 aaaggggcat aggcacgcgc ttgagcaatt gccttttgaa cactacctac tgccgcaatg
     8401 tgattgtctt ttagcatgat agcatctgat aaattaaagc gatgattata gccaccgcca
     8461 actctcacgg catatttctc aaaaagacgt aaattaggag tagtttttcg agtatcaaat
     8521 accttaatgc aatcatcgcc taaggcttct acataagcag ctgtcatcga agcaatccct
     8581 gataaatgtt gtaaaaaatt caaggcaacg cgttcacatg ttaagagact tctcaccgag
     8641 cctatgattt ctaaaaccaa atcgccacta gtcaaacgat ccccatcctt aaattgatga
     8701 ggattctgga aggtcacctc ggcatcaaat agggtaaaaa ccctttgaaa aacggttagt
     8761 cccgctaaaa caccagcttc cttggcaaaa agcgacacct tggcttggcc atgatgatca
     8821 aaaatggcat tggtactgta atcttcggaa tgaacatctt ctcgcaaggc tgctttcaat
     8881 gtatcatcta tttgaaaagg ggttaaatca gttgaaatga ttgacatcac taagtcctct
     8941 atttttaata tcacttgtaa gcactagagg caatcactat taacttccat aggaaatcac
     9001 aagcctgaat acctcatttt taattctaac aagtgtcaat acaattgtca agacaattgt
     9061 attttttttg tgtataatag tcaagtacca ataggaaaca ggtggtcttt tgagcgccaa
     9121 aattgccaac ctatttccat attctaactg aaaggacaat tcaatgattc atttaataat
     9181 gattagcgcc attgctctag ccattggaat tggttaccgc accaaaatca atattggcct
     9241 gctggctatt gctttttctt acctcatcgc aaccactctc atgggattaa gccccaaaga
     9301 acttcttcat ttttggccaa cctcactctt ttttaccatt tttagcgtct ctctctttta
     9361 taacgttgca acaactaacg gtactcttga tgttttggct caacacattc tctaccgcac
     9421 acgcacctac cctaacgccc tctacatgat tttatacctg atggcaaccc ttttgtctgc
     9481 tttaggtgct ggatttttca ctactatggc cgtttgctgt cctctagcga ttaccctctg
     9541 tcaaaaagcg gacaaacacc ctttgattgg agctcaagcc gtcaattggg gagcttcagg
     9601 aggggctaat ttgataacca gtagctcagg cattgtcttt caaggcctgt ttaagcaaat
     9661 gggatgggaa gagcaagctt tttcacttgg caatcatatc tttatcgtca gcattatcta
     9721 cccactcatc gtcttgcttt tattatcctg ttacagtcac tatagtaagg gaagaacaaa
     9781 ctcatccttg actattgacc aaccaccact cctcagcaag gttcaaagac aaaccacctt
     9841 gctcatgatc agcagcatgg ttttggtttg gctttttccc ttgttgcatc tcattttccc
     9901 aaacatcgcc tggatagcta cttatcaaaa aacatttgat attggctttg tctcaatact
     9961 catggtctgc ctcgccttaa ggctcaaatt agggaagcaa gaagccattt tagctaaggt
    10021 tccctgggct acaattatca tgctctgcgg catgagctta ctaatgtctc tagcggtcaa
    10081 gtcaggttta gtcacactga tagggcacct catgacaaca accattcctc atttctggtt
    10141 acctctgttc ttttgtgtga tagccggagt gatgtcactc tttagttcca ccctatccgt
    10201 tgtagctcca gccctctttc ccatcattgc tatcatcagt gctcaaaatc ctcagattga
    10261 tattcactta ctcacaacag ccaccgttat tggcgctcta tctactaata tctcaccctt
    10321 ttcatcagct ggttctctca ttcaactctc acttcccaat atagaggaac gtggccttgc
    10381 cttcaaaaag caaattattc tgggtgtccc catcagctta agtttgggac tcttgaccac
    10441 ctggattctc atccttctag cttccttaag ttagatttat tatctaactt aagggtggac
    10501 ttggtataat aaagtagaca caaaattaag tggaaacgag gaaaagtcat tatgccaaga
    10561 aaaacctttg ataaagcctt caaactctct gctgtaaacc tcatcctgta aaaatgatta
    10621 gttcaacttt aaaaattcat cccaatagtc tttatcgatg gattcaagaa tatgaaaaat
    10681 atgaagaaag tgcgttccca ggacatggga gcgcacttcg tcatactcaa tttgaaatat
    10741 agtgaaatga aataagacca ggacaaatag atcaggatag tcaaatcgat ttctaacaat
    10801 attttataag tagatgtgta ctattctagt ttcaatctac tatagtaaag ttgactttcc
    10861 tgtaccattt ttaccagtaa ttaatgtcac gcctgaactc aaagtatcaa aagaaatatt
    10921 atcaaacaat atacgatgat ccaccctata cgaaatattt tctactttca ttttttctcc
    10981 ttttgaacta atagcaaaag aaacagttct gttttcatac tctttcccct tcatctatat
    11041 tattcgtaat gaaaaataaa aaaaataaaa tttttttaaa tgattatgat tcagaattta
    11101 tttaatatat taaaagaaga tatgaacaaa taaattggga gattgaaatt catttctagc
    11161 aattttttag aagtcacagt ctactattct aacctcaata tactatatgt gttacaagaa
    11221 aagactcaaa aacttctcgt cagtgtaaga atgtttgaaa cactatttaa aactaaataa
    11281 ctataagaag tagatcaggt gaacaatttc agtacctact ctataagcta tacgaagata
    11341 tttttcaaca tgatggataa aacgatcact cttttaaagt catcttattt agaaaagaga
    11401 aaccatttaa gcatagatgg gaccttcttg ccctgtttta aatttttctt aaactagagc
    11461 ctgtaaaaga ttggcttcat tttcacattt tctcctagga ggaatgtcgt aatgcaaaag
    11521 aattaaattc aaataaatca tagcgatgac gactaatcga gtactcaaac ggagttccgt
    11581 tatccaaata agccacttgt tctacttcaa ataccggttc cgttggaagg agctgcaagt
    11641 aatgttgctc attttctgaa ctagaagaag ctcgtaagat ttttgtagca ctggcaatat
    11701 gcaatcctaa ctttccttca atgtaattgt aaatcgattt ttgtaaaata tcttcagtaa
    11761 tacctggaat aacatcggta ctcatataag tttgttccag aacataaggt ttaccgtcaa
    11821 taatacgcag gcggtaaata ttataaactg gactctgcaa agcgacctgt agtttttctg
    11881 ctaaaaattc atttgcaaat tctaatttga agtgaataat cctcgagtca attgtagaat
    11941 gagcatcttc agatattttt gtcagtcccc ggatatctct ttctggaacg attaattttc
    12001 tttttgagct gccacgagag agaacaaagg ttccctgccc acgttttcta aaaattaagc
    12061 cctcagaaac taacaagtct aaagcttttt tgatcgtcat tcgactacag gcaaactgtt
    12121 tagctaatgt catttcatca ggcaattgtt cgttcatggt atatttatta caaagaatct
    12181 tttcacgaat ctcattgtaa ataaataaat attttgtact catttaatct ggttctctct
    12241 ataatattct aatagtagta taacaaagtt caagaaatga ggcaaacaca agatatgtat
    12301 caacaatttt taaaaatgtc tagacaaatt ttaaaattat gctatacttt atgtatagga
    12361 taatagaaag gaggttgagc atgaaaaaaa agttagtatt tcctaatctg ttttggtggg
    12421 gagctgcttc tagcggacct cagacagaag gtcaatatgg aaaagtacat gaaaatgcga
    12481 tggactactg gttcaaaacg catccagaag attttttcga taatgtcgga cctcttgtag
    12541 ccagtaactt ttttcatact tacaccgaag atttccactt gatgaaggaa attggagtta
    12601 attctttccg cacttccatc caatggagtc gactcatcaa gaatttagag acaggtgagc
    12661 ctgatccaaa aggtattgct ttctacaatg ccatcattga agaagctaaa aagaaccaga
    12721 tggatcttgt gatgaattta catcattttg atttaccagt ggaacttctt caaaaatacg
    12781 gtggttggga aagcaaacat gtagtggagt tattcgtgaa gtttgccaag actgctttca
    12841 catgctttgg agataaggtt cattactgga caactttcaa tgagccaatg gtcattccag
    12901 aagcaggata cttatatgct ttccattatc caaatctaaa aggaaaggga aaagaggccg
    12961 tacaagtcat ctataatcta aaccttgcta gtgcaaaagt gattcaacta tatcgctcat
    13021 taggacttga tggaaagatt gggattattt taaacttgac acctgcttat ccaagaagta
    13081 attctccaga agacttagaa gcaagtcgat ttacagatga cttctttaac aaagtcttct
    13141 tgaatccagc tgttaaagga actttcccag aaagattggt aaaacagcta gagagagatg
    13201 gcgtgttatg gagtcatacc gaaaaagagc ttcaactgat gaaatcaaat acggttgatt
    13261 ttcttggagt aaactactac catccaaaac gtgttcaagc acaagcaaat cctgaggaat
    13321 atcagacgcc ctggatgcca gaccaatact tcaaagagta tgaatggccg gagcgtcgca
    13381 tgaatccata tcgtggttgg gaaatttttc cgaaagccat ttatgatatt gctatgattg
    13441 tgaaggaaga atatggtaat atcccatggt ttatcagtga aaacggaatg ggtgttgaaa
    13501 acgaagcacg gtttatcgat gaaaatggag ttatcgatga cgtgtatcgt attgaatttt
    13561 atgaagaaca tttaagatgg ctacataaag ccattgaaga ggggagtcac tgttttggat
    13621 accacgcttg gaccgcattt gattgctggt cttggaataa tgcatataag aatcgttacg
    13681 gatttatctc cgttgattta gaaacgcaaa agagaaccat caagagctca ggaagatggt
    13741 atcgcaaagt aagtgacaac aacggttttg aagtagaaat tgaggagtaa agagaggaga
    13801 tattcagatg aaaaactcaa aatttataga tcaatttgcc atctttgctg gtaaactagg
    13861 gaaccaaatt catttaaaaa ccctaagaga tgcattcgta acagtaatgc cattatatat
    13921 tttggcaggt ttaatcgttc ttttgaacaa cacggtattt aagtggattt tccaagggga
    13981 tacattaaca aaattccaat attggggaat aacaattgca aacggtactt taagtatttc
    14041 aggtatgatt attgctgtaa tggttggtta tttcttagct aaaaacagag atttcgaaaa
    14101 cccgttagca gcatcaatgc tatcattagt ttctttaatt gtgatgatgc caaatacagt
    14161 ttctgtagtt cctgacggag caaaagatgc tgtaaacatt tcaggtgttc tttcattcaa
    14221 caacacaggt acaggcgcaa tgttcgccgg ggttatcgta gcgattattg caacagaatt
    14281 attcattgaa ttatcaaacg ttaaagcttt acaaatgaac cttggtgaaa atattccacc
    14341 agctgttagt agatcattta gcgtattact tccagtcatg actgtcatct ccttatttgg
    14401 gattgtttca gcattattat tcaatataac tggaatgaac ttaatctcaa tcattacaat
    14461 ctttattcaa gaaccaattc gtcatattgg tacaagctta atcggggtca ttattattta
    14521 ctctttagga aatatgttat ggctatttgg tattcaccaa gcagttattt acagtgccat
    14581 cctagaacca ttactattaa ttaacattac tgaaaacatc actgcagcaa ataatggaca
    14641 agccattcca cacatcatca acttatcaca aatacaaaca ttcgctttaa tgggtggtag
    14701 tggatctaca ttatgtttat taatagcaac attcttagtg agtcgcaatg ctgtttctaa
    14761 aaacgtggct aaattatctt ttggacctgg tatcttcaat atcaatgaac cagtattatt
    14821 cggttaccca atcgtttata acatttcatt agctattcca tttatcacag ttccagtcct
    14881 tggtatttta atcagctact tagcaacagt tacaggattc atgagtcctg catttataca
    14941 agttccttgg actacaccag tattcttaaa tgcatggtta gcaacagcag gggacgtgag
    15001 agcagttcta gttcaattca tcatctttgc acttggagtt cttctataca ttccatttat
    15061 caaagttaat gacaaagttg ttgagcaaga aatggaaggt taagattatg aaacaaattt
    15121 tattagtatg taatgcggga atgtcgacaa gtatgcttgt taaaaaaatg caacaaagtg
    15181 cgactgaacg tgggattgaa atctctatcc aagcaaaatc aatgacagaa gctaaaaaga
    15241 atatccatga agcagatgtc attctaattg ggccacaaat tcgttatgag ttacttgctg
    15301 tgaaagaaat tgcaggaaat atccctgtag ataccattga tatgcgggat tacggaatga
    15361 tgaatggagc aaaagttctg gaacaagcac ttgcatggat aggagaaata agatgacaga
    15421 agaaatggaa tatatctgtt ttcagctcat tgccaatagt ggagcagcca aatcatcctt
    15481 tattgaagcc atccaactag ctaaggcagg aaatttaaaa gaagcgaaaa ttaaagttga
    15541 agaagcggaa gactccttag tagaagcgca caagattcac tctaatctca tacaaaaaga
    15601 agctactgga gaaaaaatag gattctcctt gctatttatg catgcagaag accaaatggc
    15661 ttcaacagag attattcagt tactatctaa agaattcatc gatctctatc aaaataaata
    15721 ggaacactgt cattcccatc tgtctttatt aatgacgact acattgtagg aacctccaaa
    15781 agttggacaa aatgattgaa aggattggat cctgcattac acaagatcca atccttttct
    15841 tttactctag tttttataat atgttgaatc tagaatagtc cactgcagtt tctaaaaaat
    15901 ttctggaaat ggatgttaag ctccaattta tttgtttata tcttatttca gtttactata
    15961 ctagcttatt attctagtga aaaattgaat gagccactat ttatttaata tgtatgatga
    16021 gggaatgact caaaaacttc ttgtcgatat aagaacatct gagatagtat tttaaaacga
    16081 aaggactata aaagctcatt tccttcgcac ttattttata gagatctatc attatactct
    16141 ttagaaatca aaaagcaaca caccttgtca tcgttttatc gtaaatctgt taatgagggg
    16201 gctagtctta tctgcaatct caaatcagtg ttttgagctg aatggcactc gttttctcgt
    16261 ttgctctttg attttaattg ggccttagta aatactactc ttaaattaaa ctatagtgaa
    16321 ttgaaataag atgtgaacaa ctctatcaga aaagtaaaa
//
LOCUS       DAVHSI010000042        16207 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.043, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000042 DAVHSI010000000
VERSION     DAVHSI010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.043"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..816)
                     /locus_tag="VVR21_001692"
     CDS             complement(<1..816)
                     /locus_tag="VVR21_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6055511.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDL"
     gene            complement(893..1189)
                     /locus_tag="VVR21_001693"
     CDS             complement(893..1189)
                     /locus_tag="VVR21_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6055512.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(1509..2408)
                     /locus_tag="VVR21_001694"
     CDS             complement(1509..2408)
                     /locus_tag="VVR21_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6055513.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILGEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(2480..3040)
                     /gene="rnmV"
                     /locus_tag="VVR21_001695"
     CDS             complement(2480..3040)
                     /gene="rnmV"
                     /locus_tag="VVR21_001695"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU6055514.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(3040..3813)
                     /locus_tag="VVR21_001696"
     CDS             complement(3040..3813)
                     /locus_tag="VVR21_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU6055515.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(4119..4784)
                     /locus_tag="VVR21_001697"
     CDS             complement(4119..4784)
                     /locus_tag="VVR21_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU6055516.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLENTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKNKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTR
                     RRK"
     gene            complement(5047..5181)
                     /gene="rpmH"
                     /locus_tag="VVR21_001698"
     CDS             complement(5047..5181)
                     /gene="rpmH"
                     /locus_tag="VVR21_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU6055517.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(5326..6540)
                     /locus_tag="VVR21_001699"
     CDS             complement(5326..6540)
                     /locus_tag="VVR21_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU6055518.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(6696..6989)
                     /locus_tag="VVR21_001700"
     CDS             complement(6696..6989)
                     /locus_tag="VVR21_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055519.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            7151..7603
                     /locus_tag="VVR21_001701"
     CDS             7151..7603
                     /locus_tag="VVR21_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU6055520.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(7638..9026)
                     /locus_tag="VVR21_001702"
     CDS             complement(7638..9026)
                     /locus_tag="VVR21_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU6055521.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            9092..10054
                     /locus_tag="VVR21_001703"
     CDS             9092..10054
                     /locus_tag="VVR21_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU6055522.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(10083..10421)
                     /locus_tag="VVR21_001704"
     CDS             complement(10083..10421)
                     /locus_tag="VVR21_001704"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055523.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDRTDEVSSKHCFEVADETDEVSSKHVFEVVDETDEVSSKHVFEVVDETDE
                     VSNHTYGKAT"
     gene            complement(10485..11495)
                     /gene="ccpA"
                     /locus_tag="VVR21_001705"
     CDS             complement(10485..11495)
                     /gene="ccpA"
                     /locus_tag="VVR21_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU6055524.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(11920..12519)
                     /locus_tag="VVR21_001706"
     CDS             complement(11920..12519)
                     /locus_tag="VVR21_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055525.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(12521..13618)
                     /locus_tag="VVR21_001707"
     CDS             complement(12521..13618)
                     /locus_tag="VVR21_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU6055526.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNVIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(13618..14355)
                     /locus_tag="VVR21_001708"
     CDS             complement(13618..14355)
                     /locus_tag="VVR21_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055527.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(14357..15241)
                     /locus_tag="VVR21_001709"
     CDS             complement(14357..15241)
                     /locus_tag="VVR21_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055528.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(15228..15422)
                     /locus_tag="VVR21_001710"
     CDS             complement(15228..15422)
                     /locus_tag="VVR21_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055529.1"
                     /translation="MKKGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(15419..15625)
                     /locus_tag="VVR21_001711"
     CDS             complement(15419..15625)
                     /locus_tag="VVR21_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055530.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         4845 a         3724 c         2836 g         4802 t
ORIGIN      
        1 tagatccacc agactatttt cctgtaaacc aagtagatag acgacactta gtaaggtaga
       61 aatccctgcc aaggtcaatc cataaagtag aagagcaatg atgaccagtt gcaccgttgc
      121 cataaacaag gcaccttgat accagagaat ccccaatccc aaaagactgg ataccagcac
      181 tgagcagata agctgtctca catcttctaa cactggtctg agagcaactc caaacaagct
      241 ctcaccagct attaagcgaa tccctgcctg acgaagggat ttgatccgat aaatcagggt
      301 cagactcata aaggtcagca gaaaaatagc taaactcagt agcaccatag gggtggccgt
      361 caatagtaag actatcgaaa atggatcttc tccattcgaa acaaagcctt gataaccaag
      421 ctctttcaag gtggtctgta agctcactcc atccaaactt cctgacacaa tcaagtaaga
      481 ccctaataaa tcactcgttt ctgcactctc cttggaggaa atggtcagac cttctggaag
      541 ctttccctca ccataagtgg cataggtaaa gcgtgtttct ccagcttcat ttggctcaac
      601 gattcgacga gcaatgagac tattgtgctc taccgccaag tgactcaaag cctctgtcac
      661 ctcttcccga ctagctactg gttgatttat catcattcct gtcacatcaa cagaaggata
      721 gttaccaaat aaaatctctt ctcgatggtc aacggaagtt atcaccatat aaagcgatac
      781 caataccatt gaaatcaaaa taaataaacg tttcatcatt tcctccaaaa agttacttgg
      841 tcacttagtg agaaggtgac caagtaaagc taaacaatag ggctatacca ttctaaacat
      901 tatagtagaa tgcaactttc tctccccaag aagtacgaat ccatgcacga gaagtccctc
      961 cagcaccagc atatcccttg tcagatgaac cagtttttct gctaacaact gttgaactat
     1021 ggtattttga agggtgatag tagtttgagt aagcaccacc gttacctgaa ccataagtcc
     1081 aaacaccacc ttctgggtat tgaacggctg cagaggcaac tgctacactt ccacctaatg
     1141 ttgctgcaat gctcgctaca agagctaatt ttttaactgt ttgtttcata ttgatactcc
     1201 tctatttttg attacaagat tgttgagtta cttgctcctc tttccattat caacgttgat
     1261 actattatat taccaaatga tattctaaaa ttatttgttt ttctctaaat tgtcaaaata
     1321 gcaccctgaa atgaactttt atagtcatta tactccatct ttatcacact atcaaggaca
     1381 tcaatgtcct taaaatctaa ctatttcata ttatttttag cttatatcta aaaaaacagt
     1441 tctaaagacg aactttagaa ctgttttgat acgaggacaa ggacattttt gtcactgatt
     1501 cactatgttt ataaatattt tttgacatcc tcttgccatt cctctgtcaa tttctttact
     1561 agaaatccat ctccaattag cttcgcaaat gttttagaag actgataaaa tgattcagct
     1621 aaactaaaat ctctttctac tcttaatgct tgcttccaca aaaacataaa tacaagaggt
     1681 ttcttttgat aatcttgagt tttatccata atttcttgta aacacgatag ataatcatta
     1741 aaacaatcag ttactcctac cttttcaaga caacacattc ctgaaataag agtatctcta
     1801 attataaaga agttttctaa tttagttacc tttttctgtt ccaaaagaaa gagcattagc
     1861 ttttcgattt gatttataaa tttggcaaga tcttttctaa tgagcatttg ataaaaaaac
     1921 aaacgaatca acaacatatc atttgttgaa taaacttctt tttctatgat ctgaggcata
     1981 tgttccccaa gtattaactc tgcatattca ggccttctag ttctagaagt atccaaacac
     2041 gcctgcaata cttcacatgc taattgttct tctttaggaa gattatcaaa gtatgtttta
     2101 taaatctctt ccaaacacgc ttccttctta tcgtactcct cttctttacc atagattggt
     2161 tcacgtaaaa tctggtattt caattctaaa taagcaggag gaagagctga aaaatccggc
     2221 ataaggctat aaactggaac tcctagccgg cgagcaatat agtctaactt gggcaaactc
     2281 ggttgcgaag ctccactttc aattcgcgac agttgacgaa ctgtcagttc ttgctcatct
     2341 ccacaaaaat ctggacgact aattcctttt tctatccgaa tctctttaat tttttgacca
     2401 attaacatca gacgcctcct cttctacctg cttcgaaaaa tactgtgaaa cttaaaaaat
     2461 tgtaacggct acatctttcc tactcataag atttcatagc ttcttccact tctgccaaag
     2521 taaccccaaa caactctagg cgtttgagga gttgcttgcc gttagaatag ccgattcgga
     2581 gagtctctcc gagatattct ctacgcttac ggctgtctgc ccctgctaga aaaccaaggc
     2641 gaatcaagtc gctacgacta atgtcaaact gactctcatg ttcaaattgt tctgtcacct
     2701 gagctagagc cgttttcagg tcttcatagc tggcatgctc aattcccaga gaacgcccct
     2761 tggtcttgga cttgggaaca gcttcatctc gcttgagaaa ggcatgctga actgttggaa
     2821 tgaccgtcat gatcatgcgc cgaatccgtt ccccattaaa atctgggtct gtaaagacaa
     2881 tgactccatg acgttggtgc aggcgctgaa tccgctctat atcctgatca ttgatggcag
     2941 aacctcgagt ctcataggtc tccacatcga aataacgttt gagattgacc gtatcatcac
     3001 gcccttcaac cacaattact tgggaaattt tctctttcat tacttgctgt ccaatccaaa
     3061 aatgcgttct gcatttgcag tcgttgccgc cgctagctct tctgtcgtca taccacgcaa
     3121 gtcagcgata aagtcgacca catagcgagt ataggctgtt ttattttcac gaccacgctt
     3181 gggtacaggt gctaagtaag gcgcatctgt ttccaccaac atcttgtcca aaggtaactc
     3241 tttagctgct tcttggaggt cagttgcctt cttgaaagtc accactcctg agaaggaaat
     3301 ggtcatacca agatccacaa acttctctgc ccactcaagc gtccctgaaa atgaatgcat
     3361 gataccacca cgaggaccaa cgccctcact cttgataatc tcataggtat cttccagcgc
     3421 atcacgggta tggacaacaa aaggcaaatc caagtcctta gatagctgaa tctgacggcg
     3481 aaaaacctgc tcctgcacct ctttgggcgc tgtcatccaa tggtagtcta agccaatttc
     3541 acctaaagcc acaaccttgg aatgttttaa cttatccaac aagtaagcct caacttcctc
     3601 tgtataagta ccagcttctg taggatgcca accaatagtc gcatagagct gctcatactc
     3661 atctaccaac tccaaggcat gctcaatcgt cggtttatca aaaccaacaa tattcatctg
     3721 tgtcacaccc atctcatcag ccaaggcaat ttcttctgcc tcacgacctg caaattcttc
     3781 tacattcaag tgtgtatgtg tatcaaaaat catctcttct aacctcgttt tctatccttc
     3841 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
     3901 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
     3961 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
     4021 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
     4081 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
     4141 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
     4201 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
     4261 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
     4321 actggtctct taggaactgt aaccatggca atggcttgca ctccaatcgt ttctgcttcc
     4381 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
     4441 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
     4501 tcctgcttgt tcttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
     4561 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
     4621 gcctggctac caccgccttc attcgcatta gcatctgagc ttccagtatt gcctccctta
     4681 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
     4741 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
     4801 aatgtgattg ttgctgtacc atctccagct acttcaactt tatagtaaaa taaaataata
     4861 acaggacaaa tcgatcagga cagtcaaatc gatttctaaa aatgttttag aaacagaggt
     4921 gtactattct agtttcaatc tactgtaaca tcgcttccga atccatttgc atctactgaa
     4981 cttttttaca aaaataaaaa tcagtagact cgagttccta ctgatttttg atagaattcg
     5041 tttggattat gcagccaaaa ctttgcgtcc tttacgacga cgagctgcca atacgcgacg
     5101 accattttta gttgacatac ggttacggaa tccgtgtttg cgcgcacgac gaagtttact
     5161 tggttgataa gtacgtttca cgatgaatac ctcctcatag attttgtatt cgtttagccg
     5221 gctataaagt gatcagttac taaacatact ttactattct atctgattct ttcacttttg
     5281 tcaatagctc taggcaaatg tttccagctt tttcgaatgc aagccctatc tacgatactg
     5341 tttcaagaaa cgagtcatct tttcttggat ttgggctaac tcatcaacac gaggaaggta
     5401 aacgatacgg aagtggtctg gttcctgcca gttaaagcct cgaccatgaa ccaagagaac
     5461 cttttcctgc ttcaagaaat caaggacaaa ctgctcatca tcatcgatac ggtacatatt
     5521 gcggtcgatt tttgggaaga tatagagccc cgccttgggt ttaacggcag acaaacctgg
     5581 aatatcttga atggcattat agatgaaatt tctttgctcg tagattcgtc caccaggaag
     5641 aagcaattca tcgactgatt ggtgaccccc caaggaagtt tgtacgactt gttgggccaa
     5701 aacgttagag caaaggcgca tattggacag catattgagc ccttcgatat agcccttaac
     5761 atgagtctta gggccagaca agaccatcca acccacacgg aaacctgcta tgcggtggga
     5821 ttttgacaga ccattcatgc tgacacagaa gacatctggt gccaagctcg ccacaggcgt
     5881 atgcacatgt ccgtccatta ccatgcggtc atagatttca tccgcaaaga taatcaaatc
     5941 gttttgacgg gcaatctcaa taatctccag caagagttcc ttaggataaa gggctccagt
     6001 tgggttattt ggattgataa ggacgattgc cttggtattg gaagtgattt ttgacttgat
     6061 atcgtcaata tctgggtacc attcaacagc ttcatcacag atatagtgaa cggcatttcc
     6121 tccagctagg ctgacagccg ccgtccatag aggatagtct ggcattggca ctaagacctc
     6181 atccccattg tccaaaagcc cctgcatgga catgacaatc aactcactga caccatttcc
     6241 aaggtaaata tcatcaatat ctacgtttgg gaatttcttc agctggcaat actgcatgat
     6301 ggccttacgg gctgagaaaa ttcctttgga gtcagaatag ccttcactat cacgcgcatt
     6361 cataatcaag tcatgaatga cctcgtctgg cgctgtaaag ccaaattctg ctggatttcc
     6421 tgtattcaga cgtaaaatct tttctccatt cgctcgcatc cgcatggctt cttccaatac
     6481 aggaccacgg atatcataag caacatgctc taacttacta gacttgttat attctttcat
     6541 cttgtttcct caattcatca ggatagtaac attataccac tagaaagaga atgcgacaag
     6601 tttactgaaa tgtgttacta gtttcgtata gaagaaaaac cttgctaaag gcgaggttaa
     6661 gaacgtagag atagcaggta ttttgcaaag acacatcaca taccaaaaga taaacctaga
     6721 aaaagcaagc ctagaaagga gtcataaaga agattaaaca tgaggaaaag cccccatatc
     6781 atcaagtaat cccaacgccc acttcgtttt gcaactagaa ataagattag atggtagagt
     6841 acatgaaaaa ctaaaaatcc aataaaactt ggataaagaa gcggtaccag actctctaat
     6901 tgacagatca tgatcacttc taccaagact gaaactagga taattccata ataaaggaaa
     6961 tttgattttt gaaaagagtt tttcatcatt ctcccttcct tcacttcttt cctgctatcc
     7021 tttcttttat tttatcatat atttatatag agtttaagcc ctaatattct tttgaaaaat
     7081 actttttttg ctttacttct atagtgaaaa ggtttacaat tatagtaaga aaatttcagg
     7141 aggtttcatt atggcacaac gttaccaaaa tatcatggtc gcaatcgatg gttctaagga
     7201 agcggacttg gcttttgtca agggagttca ttctgctcta cgaaacgacg ctaaactcac
     7261 catcgcacat gtcattgaca cacgcgctct ccaaagcgta tccacctttg atgctgaagt
     7321 ttacgaagaa ctccaagtcg acgctgaaag tctgatgaaa gagtacgaaa aacgtgctaa
     7381 agatgctggg gtagcagatg ttcatatcgt cattgaaatg ggaaatccaa agaccctgct
     7441 agcacgtact attccagatg ccgaggaagt ggacctcatc ctcgttggcg caactggtct
     7501 caacgccttt gaacgcctct tggtcggctc ttcatctgaa tacatactcc gccatgctaa
     7561 ggtcgatttg ctggttgtga gagaacaaga aaaaacctta taatcacaaa gaaaaggagc
     7621 ccctagctcc tttttgttta cgatttattt ctctctttat ggcgttcgta agccttgagc
     7681 tggcgctgca gttccttttt aatagcaggt tctggagcat atttttcttc ccaattatct
     7741 ggttttaaga ttttatgggt cactggatca aaatgagcct tgccatctgg aaaaattttc
     7801 cccatattgg cctgatggac aatatcaaaa atacgttctg ggtccacccc catcaagaca
     7861 aaactgccgt aggtgaagta aagcgtgtca atcaaggcat ccacttgccc tatcaaatct
     7921 tgctgagcag gtgtcttctt ggctacttta tctgctgcct tatcaagggc ctgatgaagt
     7981 tgcgatacag cttgaccaaa atcttcttca gaaggactgg ctgctcgaac aaactccacc
     8041 aattcttcta ttttaaaacc agccctatgg gttgcaccct ctaaatccca agctcgaggt
     8101 tcttcttggg ttcgttcatc catcatgtgg tggaaggtct tgaccttatt gaaatgatag
     8161 tcacggctga caaagacttt ttctgaagac aaaacaccaa aatgttccaa ggccttgtgg
     8221 atcccatctt gttgattgct agtggtaatg tgcttggcag cttccttgac actgctacta
     8281 ccatttccca tagcgaccga cataccgacg ccagccagca tttcaaggtc attatctgag
     8341 tcaccaaaag ccatgacttg attgaggtca aagccatatt ctttcccaac tcggcgaatg
     8401 ccttctaatt tagaatttcc ctgattgatg acatccgatg caaaaggatt gctacgtgtc
     8461 aatttcaagt cttcaaaatc agctgccgcc ttctcagatt cttctggtgt catcagcatc
     8521 aaaacttggt agataggctg attcatcagg tgaagcaggt cctcttcctt ttggggaaca
     8581 accttgctga ccatgcgatt aaaagactga ctcaccgtcc gagttaaaac agagggaacg
     8641 aagcgactaa ttcgttggga aaaagaaccc agaccaaagg acatgatttt agaacccaac
     8701 atggcatcct tggtccctag ggcaatctcc gtgccctctt ttttagcata gctaattaga
     8761 tggcgcaaat gtaacttgga aatagggctc gtgaacaaga ctctgtcttt actaaagata
     8821 tactggccat tataggttac cgcaaaatcc agatccaaat cgtccatcaa ttccttaaca
     8881 aaaaaaggtc ctcgccctgt cgctacgcca actagtaccc cttgttcttt gacaatctta
     8941 atcgcatcct tagtagattt caaaacactc ttgcgattgt tgaccaaggt tccatcgata
     9001 tcaaaaaaaa cagctttgac ttccatccta tcccaatctc cccttttgtg atacaatgat
     9061 tataccacat ttcagaaaga gttagtaaat catgcctaag aaaatccttg ttttacatac
     9121 gggtggaact atttccatgc aggccgatgc ttctggcgct gttgtgacga gttcagataa
     9181 tcccatgaac catgtgtcca acccacttga aggaatccaa gtccacgcct tggacttttt
     9241 taaccttcca agtccccata tcaaacccaa acatatgctg gtcctctacc agaaaattaa
     9301 agaggaagca gataactacg atggagtggt gatcacacac ggaaccgata ctttagagga
     9361 aacagcctat ttccttgata ccatggaagt tccccatatg cctatcgttc taacaggagc
     9421 catgcgtagc tccaatgagc tcggtagtga tggtgtttat aattacctaa gtgctttacg
     9481 agtggccagc gatgacaggg ctgctgacaa aggagttttg gtcgttatga acgatgaaat
     9541 ccacgctgcc aagtatgtca ccaaaacaca tacgactaat gtcagcacct tccagactcc
     9601 aacacatggc cccctcggtc tcatcatgaa acaggaaatc ctctacttca aaacagctga
     9661 acctcgtgtt cgctttgacc ttgatcacat acaaggttta gtccctatca tctcggctta
     9721 tgctggtatg acagatgagc tgattgatat gctggattta gaacacttgg acggtttgat
     9781 tatccaagcc ttcggagctg gtaatattcc caaagaaacg gctcaaaaat tagaaagcct
     9841 tctgcaaaaa ggaatcccag tcgctctggt atcacgatgc tttaacggta ttgccgaacc
     9901 tgtttatgcc taccagggtg ggggcgtaca gttgcaaaaa gcaggcgttt tctttgttaa
     9961 agaactcaat gcccaaaaag ctcgcttgaa actcctcatc gccctcaatg ccggactaac
    10021 aggacaggct ttgaaagact atatggaagg ctaatactct tcgaaaatct ctgcaaacca
    10081 cgtcacgtcg ccttaccgta tgtatggtta ctgacttcgt cagtttcatc cacaacctca
    10141 aaaacatgtt ttgagctgac ttcgtcagtt tcatccacaa cctcaaaaac atgttttgag
    10201 ctgacttcgt cagtttcatc tgcaacctca aagcagtgct ttgagctgac ttcgtcagtt
    10261 ctatctacaa cctcaaaaac atgttttgag ctgacttcgt cagttctatc tgcaacctca
    10321 aagcagtgct ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgtgttgcg
    10381 cagcctttaa ccagccgcct agtccgctct atggtattca ttaagtcaac atctcttgtt
    10441 taagagcaca aaatcaggaa atcttctcga ttccctgatt ttttctattt acgttttcgt
    10501 gttgagctac gttctgtcaa accatgaggt aagagaactt cacgttcttc caactcttcc
    10561 ttatgcataa tcttggtcaa catacgcata ctaatggcac caaggtcata aagaggttgg
    10621 gcaatcgttg tcaagtttgg acgggtaaag cgtgagattt gtgaatcatc actagtaata
    10681 atttcaaaat cttctggcac agaaacaccc ttatcagcca aaccgttcaa gactcctgct
    10741 gccaactcat cacctgtcac aactgctgca gttgcatttg atgaaatcaa acgctctgct
    10801 aaagcgtaac catcatcata gctatattta gattcaaata ccaaaccctc actataagtg
    10861 attcctgctt ttttcaaggt ttccttgtag ccaactaaac gaaccttacc attgatgtca
    10921 tccactagcg gaccgctaac gaaagcaata cgctcatttt ctttagcaag gtaactcact
    10981 gcatcaattg ttgcttgctt atagtcaata ttgacacttg gcaactggtg ctcaacatcg
    11041 acagttcctg cgagaacaat cggagtacgt gaacgcgaaa attctgagcg aattttatct
    11101 gtcaagtgat aacccatata gataatgcca tctacctgct ttgaaaagag ggtattgaca
    11161 acagaaactt ctttctcgtt atcttcatcg ctattagcta ggacaatatt gtacttgtac
    11221 atttctgcaa tatcatcaat ccccttagcc aaactcgaaa aataaccatt ggtaatattt
    11281 ggaatcacga caccgacagt ggttgtcttt ttacttgcaa gaccacgcgc aactgcattt
    11341 ggacgataat ccaaacgatc aattacctct agcacttttt tacgggtatt ctcttttaca
    11401 tttttattgc cattgaccac acggctgacc gtcgccatgg aaacacctgc ttcacgagcg
    11461 acatcataaa tggttactgt atcatctgca ttcattcctt ttcctgtcct ttctatctca
    11521 cacattcttt tacaagtaga ggtactgatt gaagctctat atctacttac aaaagtgaag
    11581 atgtgaaaat ttcgttttca tatttctact tattccattc tatcactaat tgtaaacact
    11641 ttcaagtgtt ttttgaagat tgattgaaaa aatttcatag aaaacctagg tttagctcct
    11701 tgctaccacc ttagactaaa caaaaaggag gaaactaagc cctcctaaag ttatagtaaa
    11761 atgaaataag aacaggataa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    11821 gaagtagagg tgtactattc tagtttcaat ctactatagg tattgttcca ttcactaccg
    11881 tcaattttag cacatagtct tcatgaaaat attatatcat cataaccaac cagattcttt
    11941 tgcgatatta gctgcctctg ttcgattacc agcatccagt tttgaaagaa tattggtgac
    12001 atagtttcga atagttccgt ttgagaggta aagctgatct gcgatttctt ggttggataa
    12061 gccccgggca attcccttta agacagcaat ctcttgttct gtcaacggat tgggacgggt
    12121 catcaccact tccatcaatt caggtgaata ctccttgcgt ccttcgagga cggtgtgcaa
    12181 ggtttgcatg aggtctgcaa tgcttcgttc ctttaataca taagcatcta ctccagcctt
    12241 gaccgcacgt tcaaaatacc cagcacgctt gaaggtcgtc accacaacca cctttgtttc
    12301 aagcctttct gatcgtatcc actccaagac ttcaagacct gtcttaacag gcatttctac
    12361 gtcaaggatg gcgatatcta cagactcctt ttctaatagt tggattgctt cttgcccatt
    12421 cttggcttga aggacagact ccacatctgg ttgaagcgtg agcaattgac acatggcatc
    12481 tcgcaacata ctttgatctt ctgcgactaa tactttcatc ttagtttctc tccttataag
    12541 gtagtcgaac ttgcacttcc gttggatgtt tctgactgat tacacttact tctcctgaaa
    12601 atggaaaaac acgatctcgg actgtatgga gctcatctcc ttttagaaaa gcaaagccgc
    12661 agccatcatc acttactgtt aaaatgagtt ccttctctgt ccgttctaat tttaagtaag
    12721 ctttagacgc tttggcatgt ttgatgacat tggtcaccaa ctcaagcaaa atcatagaag
    12781 ccattgaatc caattcttga gtaaggctag cagtatctag ttggttatct gtttccacct
    12841 caattccagc aatttctaac atctttttca cagtctctag ttcggatgtc aaagttctag
    12901 acttaagatt ttccacaatg gttcgaactt cacacattga ttctttgcta atttgctgta
    12961 tttctcttaa ttccttttcc acttgtggat aagcctgcat ttgaaatagc tgcaaggcta
    13021 gatctgtctt gacactaagc atagcaaagg tatgtcccag actatcatgc aaatcctgac
    13081 cgatacgatt gcgctcattt tctgctagca atagatttat ctgggtattt tgcttgacct
    13141 gagcttcttt caaatcctcg acaaggcgaa ttcgaaccga gcccaaagtc atcaaatcga
    13201 caaaagtaag aattacaagc atatagacta gaaactcaac ttcgattctc tgaaaaatca
    13261 aaagtcgccc cacaacaagg acttgagcaa ggagaaatgt ccatacatgt aaagacttta
    13321 aactacgtac gccaaaatga taaattaaga gattggaaag gaaaaagaaa aaccagatat
    13381 aattcccagc aacaaaggcg gtattcccag ctacatagac cagcatgagc ccccagaaaa
    13441 gccaagatag gcgctggttc ttagttatta aaacacccaa atacgtcact acaaatagaa
    13501 tatcaaccaa taaatgccaa gcaggaagct ccccaatcac tacaggtagg atgggaaaaa
    13561 gcataaaaat caaactggtc caaaacatat agtgtatgct tttcagtctt tcaagcatta
    13621 agcattctcc ttatgacctt gaaggtaaat agtcaaacca aataaaactg ctgaaaaaac
    13681 aagtaaataa actgtggctg atagattgat gtccccctcg tttaagaagg tcttgagcaa
    13741 ctccatcaat tgataggtcg ggagacactt accaactgct tgcatccagt ctggaaataa
    13801 agaaatgggc atccagagtc cgcctaaaac agccaatcct agataaagaa gattgcccac
    13861 aacagacatc agctgactag ttggtaagag agtcaaggtc aagccaagtg ctacaaaagc
    13921 aatactcccc acaatcagca aaatcgcagc tccaacccat tttactagag gcatgtctac
    13981 acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt gagaccaaat aatcaaccag
    14041 catacttgtt atctttgata gataatattc taccatattt acagggctat gacgcaatgt
    14101 tttctgccag ttgttcatct tatcggtatg taaaacagct ggaaatgaga ggatagttgt
    14161 cgacatcatg gaaaaggcag tcatggagat gaggtaatca cgcataaaat tcgcgagttc
    14221 acctggtgtg tcctgataga taccagaaaa aaataaatag aaagccgtcg gcatccctac
    14281 cgacaataga taatagatta attgtcgttt ggtcaataaa aattctatct tactaagtgc
    14341 tatccatcgt ttcatcttag ttatctccct tctgcgtctc ttcaaagatt gtattcaaca
    14401 aactacgatt attaacttcg atttcttgca tcctacatcc tgcttgggct aatagttccc
    14461 agaaagcatc tgcttctcga gtgactactt gtaaagaatc ttgctttagg gtccagtttt
    14521 caaccaaatt tgactgctct acgacttcct tgtaagctat aggaaggata aagtgctttt
    14581 ctatttcctc gctacgcata gctagaggcg tcgtatctcg aatcaactct cccttattta
    14641 agagcaaaat gcggtctgca gtgtgttcca cttcctcaat ataatgggac gaatagagaa
    14701 tggtgactcc ttgcgctttt aactcctgga caatttccca aaaacgttga cgagttgagg
    14761 tatccatgga cgcagtaggc tcatctaaaa aaacaatctt tggtcgccca attaaggtca
    14821 agacgaaaga aaagagacgc ttttgaccgc ctgataattt ttctgccaac tgttcttttt
    14881 gttgcttgac aaactgcaat agttgatcaa tttcctgatt gctcaaagga tttggataga
    14941 tacgttgaaa gaaagcaatc aactctttaa cttttaattt ctgaacgatt acattttctt
    15001 gagggaggta agccctagta tagtctaact tagaactcgt cactggtaaa ccttgaatag
    15061 atacttgacc gcttgtgacc agtttatctc caagcaaaca atctaagagt gttgtctttc
    15121 cggcaccatt tggaccaatt aaggcaacac attcaccatc gttgatttca aaggagatat
    15181 tccgcaaaat ttccttgtct tttattttct tactcaattt ctcaacttta accaccgtca
    15241 tgagactctc ctttcaacca ctccattccc ataaggaaaa cgacgaaaat cataaatcca
    15301 aaccccaaag caccacgaat gaattggcga agcaaggctt gatcaaacca atcagtaaac
    15361 atttccacta accataccaa gagtgacagg ccgataaaga aatagatgat ccctttcttc
    15421 attcctcaaa ctcctttttc acatctctga ctaatttcaa accttctcta acaagccaag
    15481 acatgattcc aaagccagca aagaccttcc aaggaaaatg gtagaaatcc tcatccaatc
    15541 ccgaaaacat gagataggtc ataactcctg ctactactaa acttactgcg ataatcattt
    15601 tatttctcat ctcttcttcc cccatttcat actacaatta tagtctttta aaatcagagg
    15661 agacagaagc ttctgtcact agaaaatatg acaaatgtca taaaaaattc tgttcaaaac
    15721 aagcaagata cactatacaa taaaacacaa tcagaaaaat ctaaggcaac ttcctcaaaa
    15781 gagatatcaa acccaattca caccataatg taaactaata cttatttaaa atcaaaaaga
    15841 gtagaaattt ttatcagaca aacacatata tagtgtattg aatctataac agtaggcctt
    15901 aaatactaaa atatttctat aaattaattt aactttcctg atagaactgt tcatatctta
    15961 tttcaattct ctatattata cgttgaacca aacccttcta ttgctttctt aaaaatttat
    16021 aagagttata aaatctgtta aatttcaatg tgtataccta aactacggta tttattgaaa
    16081 agactgggga caaaaagtat acgctgccaa aatgaattac tgaaaatcaa aaaagagaga
    16141 accaaactga ttccctctta atgtatataa tatctagttt taaaaataca cactcacata
    16201 tctctgt
//
LOCUS       DAVHSI010000043        15838 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.044, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000043 DAVHSI010000000
VERSION     DAVHSI010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.044"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..701
                     /gene="phtB"
                     /locus_tag="VVR21_001712"
     CDS             <1..701
                     /gene="phtB"
                     /locus_tag="VVR21_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU6055531.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESP
                     EESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIM
                     AEAEKLLALLKESK"
     gene            844..1218
                     /locus_tag="VVR21_001713"
     CDS             844..1218
                     /locus_tag="VVR21_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055532.1"
                     /translation="MTTSYLKSKSDNGGGTYCLDNIELLANIDFIKIFEEISTSSKID
                     IVTYSFYDDEFLKALLYDKINVRVLLSKISNQSQHYTDLIREIVPNSEVIQVEETHAK
                     IVLAEPNFVYLGSQNIDQSDWF"
     gene            1306..1506
                     /locus_tag="VVR21_001714"
                     /pseudo
     CDS             1306..1506
                     /locus_tag="VVR21_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1671..2609
                     /locus_tag="VVR21_001715"
     CDS             1671..2609
                     /locus_tag="VVR21_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FRG domain-containing protein"
                     /protein_id="HEU6055533.1"
                     /translation="MVIKKYFVNSIESYIQTIREINSANPSHRLWYRGQKSSEYGLIP
                     GIWREAYSVSDSRGERIPIHRTNFYNPKGEVVVMPSQNVLLEKFMSKAMTEDILGPKN
                     EVQWLELAQHYGLPTNLLDWSTDPLVALFFAASTVDCKNDNETYLTEDQVIVREDDED
                     EDEIIHAHASVWVINPLEINQILLNEPGIEGVFQSFNPNDIEKINKEISLNCGTFCFE
                     GSKINPRITRQSGNFTHSGTKLTHPLDFLAAVQSKIIKINIPYSCISKIITDLNKLDI
                     TNESIYFGRTERDLTAERIKGEVYSEFKEYLNSIIE"
     gene            2670..3383
                     /locus_tag="VVR21_001716"
     CDS             2670..3383
                     /locus_tag="VVR21_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU6055534.1"
                     /translation="MSYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTERLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            3417..4019
                     /locus_tag="VVR21_001717"
     CDS             3417..4019
                     /locus_tag="VVR21_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055535.1"
                     /translation="MTIEEYNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            4157..4810
                     /locus_tag="VVR21_001718"
     CDS             4157..4810
                     /locus_tag="VVR21_001718"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU6055536.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            4820..5284
                     /locus_tag="VVR21_001719"
     CDS             4820..5284
                     /locus_tag="VVR21_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU6055537.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            5297..6565
                     /locus_tag="VVR21_001720"
     CDS             5297..6565
                     /locus_tag="VVR21_001720"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU6055538.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGTLAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            6579..6839
                     /locus_tag="VVR21_001721"
     CDS             6579..6839
                     /locus_tag="VVR21_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055539.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            6850..8211
                     /gene="pdrM"
                     /locus_tag="VVR21_001722"
     CDS             6850..8211
                     /gene="pdrM"
                     /locus_tag="VVR21_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU6055540.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            8365..9333
                     /locus_tag="VVR21_001723"
     CDS             8365..9333
                     /locus_tag="VVR21_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU6055541.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEKIQAQVKEAVEASVKFAEESPFPPLESAFEDIYTD"
     gene            9349..10341
                     /locus_tag="VVR21_001724"
     CDS             9349..10341
                     /locus_tag="VVR21_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU6055542.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            10559..11602
                     /locus_tag="VVR21_001725"
     CDS             10559..11602
                     /locus_tag="VVR21_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU6055543.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            11666..13351
                     /gene="lpdA"
                     /locus_tag="VVR21_001726"
     CDS             11666..13351
                     /gene="lpdA"
                     /locus_tag="VVR21_001726"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU6055544.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            13415..14404
                     /locus_tag="VVR21_001727"
     CDS             13415..14404
                     /locus_tag="VVR21_001727"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU6055545.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(14477..15547)
                     /gene="xerS"
                     /locus_tag="VVR21_001728"
     CDS             complement(14477..15547)
                     /gene="xerS"
                     /locus_tag="VVR21_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU6055546.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
BASE COUNT         4974 a         2867 c         3373 g         4624 t
ORIGIN      
        1 aacatcagga ttcaggaaat actgaggcaa aaggagcaga agctatctac aaccgcgtga
       61 aagcagctaa gaaggtgcca cttgatcgta tgccttacaa tcttcaatat actgtagaag
      121 tcaaaaacgg tagtttaatc atacctcatt atgaccatta ccataacatc aaatttgagt
      181 ggtttgacga aggcctttat gaggcaccta aggggtatac tcttgaggat cttttggcga
      241 ctgtcaagta ctatgtcgaa catccaaacg aacgtccgca ttcagataat ggttttggta
      301 acgctagcga ccatgttcaa agaaacaaaa atggtcaagc tgataccaat caaacggaaa
      361 aaccaagcga ggagaaacct cagacagaaa aacctgagga agaaacccct cgagaagaga
      421 aaccgcaaag cgagaaacca gagtctccaa aaccaacaga ggaaccagaa gaagaatcac
      481 cagaggaatc agaagaacct caggtcgaga ctgaaaaggt tgaagaaaaa ctgagagagg
      541 ctgaagattt acttggaaaa atccaggatc caattatcaa gtccaatgcc aaagagactc
      601 tcacaggatt aaaaaataat ttactatttg gcacccagga caacaatact attatggcag
      661 aagctgaaaa actattggct ttattaaagg agagtaagta aaggtagcag cattttctaa
      721 ctcctaaaaa caggatagga gaacgggaaa acgaaaaatg agagcagaat gtgagttcta
      781 gttctcattt ttttcatgaa aatgatagat ttataaaatt gaaagggaaa cggtgtaaaa
      841 gttatgacaa catcttattt aaaatctaaa tctgataatg gtgggggcac ttactgttta
      901 gacaatatag aattgttagc aaatattgat tttatcaaaa tatttgaaga aatttctact
      961 tcttctaaaa tcgatatcgt tacttatagt ttttatgatg atgaattttt aaaagctcta
     1021 ctctatgata aaatcaatgt cagagtccta ttaagtaaaa tctctaatca aagtcaacat
     1081 tacacagatt taattcgaga gattgtacct aattcagagg tgatacaagt cgaagaaact
     1141 cacgctaaaa tcgttctggc tgaacctaat tttgtatatc tagggtccca aaatattgat
     1201 caatcagact ggttctagac aagcgtagtt attagagacc aagaaattta taaatagact
     1261 tcctgcgaaa caaaaatata atacaataaa actatgaatt atgaatcaag taaacttaag
     1321 ccactaactc ttgaagataa atcctataac catgtgctat ctaaagagag aatcaaggtt
     1381 gagaatattt ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta tcgaaatcga
     1441 cgtaaacgct ttggattacg aatgaatttg attgctggaa ttatcaaccg tgaactagga
     1501 ttttagtttc gcaggaagta taataatatg agttcgattt ttaatatcct atttatttaa
     1561 aacatagaaa aatgaaaacc cttaaaaaga aaggaagaag aattttaaaa taattattgg
     1621 agtattttta gcttttttac ttttttaagt gtaaatggta taatatacct atggttataa
     1681 aaaaatattt tgtaaattca attgaatcgt acattcaaac tattagagaa attaattcag
     1741 cgaatccatc tcatagacta tggtatagag ggcaaaagag ttccgaatat ggcttgattc
     1801 ctggaatttg gcgtgaggct tattctgttt ccgattctag gggagagaga atcccaattc
     1861 atcgaacaaa cttttacaac cctaaaggag aagtagttgt tatgccatct caaaatgttc
     1921 tccttgaaaa atttatgagt aaggcaatga ctgaagatat cttagggccg aaaaacgaag
     1981 tacaatggtt agaattagca caacattatg gcttaccaac aaatttatta gattggtcta
     2041 cagacccatt ggttgcatta ttttttgctg cctctacagt tgattgtaaa aatgataatg
     2101 aaacttacct aactgaagat caagttattg ttcgagaaga tgatgaagat gaggatgaga
     2161 taattcatgc tcatgcttct gtatgggtaa ttaatccgtt agaaataaac caaatcttac
     2221 taaacgaacc tggtatagaa ggagtttttc agagtttcaa tcctaatgat atcgagaaaa
     2281 ttaacaaaga aatttctttg aattgcggca cattttgttt tgaggggtct aaaattaatc
     2341 ctcgtatcac cagacaatca ggtaacttca cgcactcagg aacaaaactt acgcatcctc
     2401 tagatttttt agcagctgtt caatcaaaaa ttataaaaat aaatatacct tatagttgta
     2461 tttccaaaat tataactgac ttaaataaat tagatattac aaatgaatct atatattttg
     2521 gacgtactga aagagatttg actgcagaaa gaattaaagg cgaagtttat tcggaattta
     2581 aggaatatct taattcgatt attgagtaat cattatttgt acacccccat ttgaaccatt
     2641 gcaccccctc tagaaaggaa aacctcaaat tgtcctacaa atttctactc ttcgacctcg
     2701 accacactct tcttgatttt gatgctgctg aggatgtggc tttgacccaa cttctaaaag
     2761 aagaaggagt tgcggatatt caggcttata aagattatta cgttcctatg aacaaggctc
     2821 tctggaaaga cttggagcta aagaaaatca gtaaacaaga actggttaac acgcgctttt
     2881 ctcgtttatt tgctcatttt ggacaggaaa aagacggtag ttttcttgcc cagcgttacc
     2941 aattttacct cgcccagcag ggacaaacac tatcgggcgc tcatgatctc ttggacagcc
     3001 tcattgagcg tgattatgac ttgtatgctg cgacaaatgg cattactgcc attcagacag
     3061 aacgtttggc tcaatctggt ctagcacctt atttcaatca agtctttatc tcagaacagt
     3121 tgcaaactca aaagccggat gctctctttt atgaaaagat tggccagcaa attgctggat
     3181 ttagtaaaga aaagacgctg atgattggag attctctaac cgccgacatt caaggtggca
     3241 ataatgcggg gattgacact atctggtata atcctcatca cctcgaaaat cacacacaag
     3301 cccagccgac ttacgaagtc tattcttacc aagacttgct ggattgttta gataaaaata
     3361 ttcttgaaaa gatcacattt taaaggagac gagctaatga ctacaaaaaa gctaatatta
     3421 ctattgaaga gtacaatgaa gctgttaatt atgaatttac atctgacact tgtcaattag
     3481 caaatagtat ttatcaatct ctttttaagt tttttgataa gaaaaatttc tctggcgatt
     3541 taatttttac ttggaaatct ccatcattag tcaaagaagg ggattatatt gggagaaggg
     3601 attcacaagt agataatctt agagtaatag gaaatatatt tccgaattat cttactaatc
     3661 gaaaatatag cctcaatatg aatcgtaatg gctgtatggg agattttcct catgactttt
     3721 ttgatatata cctagatcat gtagcaaaat atgcctacga acaaaaagtt aataatatta
     3781 aagagtatta tcctttaaaa agagcgattt tacaccaaga gaatgcattg tattttcgat
     3841 tgttttctaa ttttgacgac tttttagaaa aaaattattt aaagactata tggcaagttt
     3901 ctaaagaaac tcctttttct gaaatggatt ttaatatgtt taaaaatatt tcagaaaaga
     3961 taatcttcga aagaggtagt aaaatgctta atgatttaaa aagtaattat aaaaaatagc
     4021 cagtctttat aaactgtatt cacgtattca aatcgtatat atagtcgatt tattaaatct
     4081 ttagataaac tgtaaaaagt ggtttccata gccacttttt gctataatag aggcagtaaa
     4141 aatgaaggag ttggctatgg aacactcgtc ttggcacgct ttgattaagg cgcaattacc
     4201 tgagggttat ttcgggaaaa tcaatcagtt tatggagcag gtctattctc aggggactat
     4261 ttatccaccc aaggaaaagg tttttcaggc tctcttgaca acactgcttg aagaagttaa
     4321 ggtggtaatt ctagggcaag acccctacca cggaccaggt caagcgcagg gcttgagttt
     4381 ttctgtacct gactctatcc cagctccacc atccttgcaa aatatcttga aagaattgtc
     4441 agatgatatc ggagttaaga aatctcatga tttgacagct tgggctgagc aaggagtctt
     4501 gcttcttaat gcttgtttga ctgttcctgc tggacaggcc aatggtcatg ctggtcaaat
     4561 ctgggagcct tttactgatg ctgtgattca ggtggtcaat catctagata gaccagtcgt
     4621 ttttgtactc tggggagctt atgcacgtaa gaagaaggca ttagttacca atcctcatca
     4681 cttgattatc gaatcagccc atccaagtcc tttgtcggtt tatagaggat tttggggttc
     4741 caagcccttt tccaaggcca atgcattctt aaaagagaca ggacaagagc caatcgattg
     4801 gcttagataa ggagaaaata tgcctcagtt agcgacgatt tgctacattg ataatgggaa
     4861 agaactgctc atgctccatc gtaataagaa acccaatgat gtccatgaag ggaaatggat
     4921 tggtgtgggt ggtaagctag agagaggaga gacgccccag gaatgcgcgg cgcgtgaaat
     4981 ccttgaagaa acagggctca aagccaagcc agttctaaaa ggtgtcatca cttttcctga
     5041 atttacacca gatttagact ggtacaccta tgtttttaag gtgacggagt ttgagggcga
     5101 cttgattgac tgcaatgagg ggacgctaga atgggttccc tatgacgagg ttttgagcaa
     5161 gccgacttgg gaaggtgacc acacctttgt tgagtggctt ttagaggata aacccttctt
     5221 ttcagctaag tttgtttatg atggggataa attgttggat acccaagttg atttctatga
     5281 ataaaggaga aagcagatgc tactaatcaa aaatggtcgt gtaatggatc ctaagtctgg
     5341 tttggatcaa gtttgtgatg tcttagttca agatgggaaa attatcaaaa ttgcgcctga
     5401 gatcacggaa gaaggagcag aaacgattga tgctactggt cttgtggttg ctcctggttt
     5461 ggtcgatatt catgtgcatt tccgtgaacc tggtcaaaca cataaagaag acattcatac
     5521 tggtaccctg gcagccgctg caggtggttt tactactgtc gtcatgatgg ctaataccag
     5581 tccaaccatt tcagacgtgg agactttgca agcagttctc cagtcagctg ccaaagagaa
     5641 gattaatgtc aagacagttg cgaccattac taaaaacttt aatggtaaaa acttgactga
     5701 ctttaaggcg ctcttagaag ctggtgcggt tggtttctct gatgacggta ttccgcttga
     5761 gagcagtaag attgtcaagg aagccatgga ggaagccaaa aaactcaata cctttatcag
     5821 ccttcatgag gaagatccag gtttgaacgg tgttcttggc tttaatgaaa atattgctag
     5881 agaacatttc catatctgcg gtgctactgg agtggctgag tacgctatga tggcgcgtga
     5941 tgtcatgatt gcctatgcaa ctaaagccca tgttcacatc cagcatttgt ctaaggaaga
     6001 aagtgttaaa gtagtggagt ttgctcaggg gttaggtgca gaagtcacag cagaagtagc
     6061 accacagcat ttctctaaga cagaagcact tcttttaaca caaggtagca atgctaagat
     6121 gaatccaccg cttcgtttgg aatcagaccg tcgtgccgtt atcgaaggtc tcaaatcagg
     6181 tgtcatcaca gttattgcga ctgaccacgc gcctcatcat gtagatgaaa aaaatgttga
     6241 agatattacc aaagcgccat ctggtatgac tggcttagaa acatccctgt ctctcggctt
     6301 gacctatttg gtagaagctg gtgagttgag cttgatggaa ttacttgaaa aaatgacata
     6361 caacccagcc aagctttaca actttaaagc aggttacttg gctgagaatg gtccagcaga
     6421 tatcactatt tttgatgcca aggctgaccg ccttgtggac tcccattttg cttccaaagc
     6481 agctaattca ccattcatcg gtgaaacctt aaaagggcag gttaaatata ccatctgtaa
     6541 gggacaaatc gtctatcaag cttgatagga gttagaatat gaattatttt cgaaaacgta
     6601 gggagagaca agcgaaatct aatagtggaa tttactgtcc cgcagctaat cgttccaaaa
     6661 ttcaatatga aactaaagaa aaagctgacc atgcggttca atatgataac ggaggtttgg
     6721 ttagaagcta ttattgtcgt acatgtgcgt gttggcatac tacttcaaaa tctaataaac
     6781 ctccgctaag tttgaaaaac tatggtctga aactctttgg tttagataaa tcagaataga
     6841 aagagaagta tgtataagac aaagtgttta cgagagaagt tggtattatt tttaaaaatt
     6901 ttcttcccaa tcctgattta ccaatttgcc aattattctg cctcttttgt tgatactgca
     6961 atgacaggtc aatacaacac tatggacttg gctggtgtat ctatggcaac cagtatctgg
     7021 aatcctttct ttacatttct aacagggatt gtgtcagcct tggtgcctat cattggtcac
     7081 catcttggtc gaggaaaaaa ggaagaagtt gcgtctgatt tttaccaatt tatttatttg
     7141 gccttgggcc tatctgtggt cttgctgggg atggtacttt tcttggcacc aacaatcttg
     7201 aatcatattg ggttagaagc agcagtagcg gcagtagcgg ttcgctatct ttggttttta
     7261 tctatcggga ttatcccctt gttgctcttt agcgtcattc gttccttgct ggattcgctg
     7321 ggcttgacca aactgtccat gtacctcatg cttttgttac tccctctcaa tagcggattt
     7381 aactatctct tgatttacgg tgcctttggt gttccagaac tgggaggggc tggtgctggt
     7441 ttaggaacat ccttggccta ctgggtcttg cttgggattt ctgttctggt tttatttaaa
     7501 caggagaagc tcaaagcctt acaccttgag aaacgaattc cacttaatat ggataaaatt
     7561 aaggaaggag ttcgtttagg tctgcctatt gggggaactg tcttcgcgga agtggctgtc
     7621 ttttcagtgg ttggcttgat tatggctaag ttttcgtcct tgattatagc tagtcaccag
     7681 tcagctatga acttttcaag tcttatgtac gcctttccta tgagtatctc atcggctatg
     7741 gctattgtcg tttcctatga agtgggagcc aagcgatttg atgatgcgaa aacctatatt
     7801 ggtctaggaa gatggactgc cctcattttt gcggccttca ccttaacctt cctttacatt
     7861 tttaggggaa atgtggccag tctttatggt aacgacccaa aatttatcga tttgacagcg
     7921 cgttttttaa cttatagtct tttcttccag ttagcagata cctttgcggc gccgcttcag
     7981 ggaattttgc gggggtataa ggatacagtt attccttttt accttggttt gcttggttat
     8041 tggggcgtag caatccctgt ggctacgcta tttgattccc taacagattt tggagcttat
     8101 tcttactgga tcggcttgat tattagtttg attgtgagcg gggcgctcta ccgttggcgt
     8161 ttaactgtga ttatgaagag atttgaatct ttagcaaaat ccaaacgcta aaaagtttgt
     8221 gaaaaaatat tcttgacaag aaaatccctt gttttcacgg ggttttcttt tttattttgt
     8281 gaaatttctt ttagaaaaac tttgacagta tttgccaaaa gcggtaaaat agtaaggtaa
     8341 gaagaaagtt agaaaggcaa gaagatgtca actttagata aaaatctttt gctagaaatg
     8401 ttccgtaaga tggaagaaat ccgtcgcatg gacttaaaaa ttgcacaatt agtaaagaaa
     8461 gggaaagtgc caggaatgac gcacttttct gttggtgaag aggcagctaa cgtgggggct
     8521 atgttagctc tcaatccaga tgatctgatt acctcaaacc accgtggaca cgggcaagct
     8581 attgctaaag ggattgacct caacggaatg atggctgaaa tccttggtaa atacactgga
     8641 acctgtaaag ggaaaggtgg atctatgcat atcgctgacc ttgatgctgg gaaccttggt
     8701 gccaatggta tcgtaggtgg tggtatgggg atcgctgtcg gtgcagccct cagtcagcaa
     8761 atgcaaaata ccggtaaaat cgttgtttgc ttctttggag atggtgcgac caatgaaggt
     8821 gttttccacg aagcagtgaa catggcttct atctggaacc tgccagtcat tttctattgc
     8881 attaacaacg gttacggtat ctctgcggat atcaagaaaa tgaccaatat agaacatatc
     8941 catcaacgta gcgccgctta tggaattcct ggaatgttca tcgaagacgg taacaatgtc
     9001 atcgatgtct atgaaggatt tcagaaagct gtagaccatg ttcgcagtgg caatggtcca
     9061 gtcttgattg aaagtgtaac ttatcgctgg cttggtcact catcatctga ccctggtaaa
     9121 tatcgtacgc gtgaagaagt ggaattgtgg aaacaaaaag atccaatcga aaacctccgc
     9181 aattacctta ttgaaaataa cattgcaagt gccgaagaat tggaaaaaat ccaagcgcaa
     9241 gtaaaggaag cagtagaagc ttctgttaaa tttgcagagg aaagcccatt cccaccgctt
     9301 gaatcagcct ttgaagatat ttacacagac taaggagaaa gagataaaat ggaaacaaaa
     9361 acaatgtcct tccgtgacac cattatcctt gctatgtctg aggaaatgcg tcgcgatgaa
     9421 aatgtgttct tgatgggaga agatgtcggt gtcttcggag gagacttcgg tacttctgtt
     9481 ggaatgcttg aagaatttgg tccagaacgt gtccgtgact gtccgatttc tgaagctgcc
     9541 atctctggag cagcagcagg agcagccatg acaggacttc gtccaatcgt cgatatgacc
     9601 ttcatggact tctctgttat tgccatggac aatatcgtca accaagctgc taaaacacgt
     9661 tacatgtttg gtggtaaagg tcaggttcca atgactgttc gttgtgcagc tggtaacgga
     9721 gttggctctg ccgcccagca ctcacaatct ctagagtctt ggtttactca cattccagga
     9781 cttaaggttg tggcacctgg aacacctgcg gacatgaaag gcctgcttaa gtcttctatc
     9841 cgtgataaca acccagttat tatacttgag tacaagtcag aatttaacca aaaaggggaa
     9901 gtgccagttg atccagacta cacaattcca cttggggttg gtgaaatcaa acgccaagga
     9961 acggatgtaa cagttgttac ttatggaaaa atgcttcgcc gtgtggttca agctgctgaa
    10021 gaattagcag aagaaggaat ttcagttgaa attgttgacc cacgtaccct tgttccgctt
    10081 gataaggata tcatcataaa ctcagtgaag aagactggta aggttgttct ggtcaacgat
    10141 gcccacaaaa caagtggcta tatcggtgaa atttcagcta ttatttcaga atcagaagca
    10201 tttgactatc tagatgcacc aattcgccgt tgtgcaggag aagatgtgcc gatgccttat
    10261 gcacaaaacc tagaaaatgc aatgattcca acagttgaaa gtatcaaaga tgcaatccga
    10321 aaaacttata acaaagaata gagttgcata agataagtta tgtaaataaa ataaagctga
    10381 cgagaaactt tgtatctttt aggtgcagag ctcttcgtca ttaatatctt agattagagc
    10441 acgggctaaa agctcggaaa aaagataaat ctccttggct tcatcgaagc catcgtcgat
    10501 ttcctatttt tcagtcgctt ttgacgccct ttgtatcata aatagaattg gagaggtcat
    10561 ggctgatgac aagctaagag cgactcctgc agctagaaag ttagcggatg atttagggat
    10621 aaacctctac gacgtttctg gctcaggtgc aaacggtcgt gtccacaaag aagacgtgga
    10681 aacttataaa gacacaaacg tggttcgcat ttcgccactt gcaaaacgaa ttgccctcga
    10741 acataacatt gcttggcagg aaatccaagg aaccggtcat cgtggtaaaa tcatgaagaa
    10801 ggatgttttg gccctgcttc ctgaaaatat cgaaaacgat agcatcaaat ctcctgctca
    10861 gattgaaaaa gtggaagaag tccctgataa cgtaacacca tatggtgaaa tcgagcgtat
    10921 tccaatgaca ccaatgcgta aggttattgc ccaacgcatg gttgaatctt acttgactgc
    10981 gccaaccttc accctcaact atgaagttga tatgactgaa atgttggctc ttcgtaagaa
    11041 ggttcttgag ccaatcatgg aagcaactgg gaagaagact actgtaacag accttctttc
    11101 gcttgcagtt gttaagactc ttatgaaaca cccatacatc aatgcttcat tgacagaaga
    11161 tggcaagact attatcactc acaactatgt caatcttgcc atggcagttg ggatggataa
    11221 tggattgatg acacctgttg tttacaatgc tgagaagatg agtctttcag aactggttgt
    11281 agcctttaag gatgttattg gccgtacctt ggatggtaaa ttggctccaa gtgagttaca
    11341 aaattcaaca ttcacaatca gtaatttggg aatgtttggt gttcagtcct ttggcccgat
    11401 tattaaccaa cccaactcag ctatccttgg tgtcagttcg acaatcgaga agccagttgt
    11461 tgtcaatggt gaaattgtga ttcgcccaat catgagttta ggattaacca ttgaccaccg
    11521 tgtcgtagat ggtatggctg gtgctaagtt tatgaaggac ttgaaagagt tgattgaaac
    11581 cccaatctca atgttgattt aagagcaaga gtattcattt ttaagatata gataaaggaa
    11641 ggaagacatg gccttagaag taattatgcc aaaagccggc gtggatatga cagaaggaca
    11701 aatcgtccaa tggaataaaa aagtcggaga atttgtaaaa gaaggagaaa tccttttgga
    11761 aatcatgact gataaagtca gcatggaatt ggaagccgaa gaagatgggt acttgattgc
    11821 cattctcaaa ggagatggtg aaactgtccc tgtaacggaa gttatcggtt accttggtga
    11881 agaaagggaa aacatcccaa cagctggagc agcatcgcca gaagctagcc ctgtacctgt
    11941 agcaagtacc tcaaacgatg atggtaagag cgatgatgct tttgatatcg ttgtgattgg
    12001 tggaggtcct gctggttatg ttgcagccat taaagctgcc caactcggcg gtaaggttgc
    12061 ccttgttgag aaatctgaac ttggtggaac ctgcttaaac cgtggatgta ttccaaccaa
    12121 gacctacctt cataacgctg aaattattga aaatatcggt catgctgcaa atcgtggtat
    12181 cgtgattgaa aatcctaact tcactgttga tatggaaaaa cttttagaaa ctaaatctaa
    12241 agttgttaat actcttgttg gtggtgttgc aggacttctt cgtagctacg gagttactgt
    12301 tcataaagga attggtacaa tcactaaaga caagaacgtc ttggtaaatg gttctgaatt
    12361 gcttgaaacc aagaaaatca ttcttgctgg tggttcaaaa gtcagcaaga tcaacgtccc
    12421 tggtatggaa tcatcacttg tcatgactag tgatgacatt cttgaaatga acgaagtgcc
    12481 agaaagcctt gttatcatcg gtggtggagt tgtcggtatc gaactcggtc aggccttcat
    12541 gacatttggt tcaaaagtga ctgttatcga aatgatggac cgtatagttc cagctatgga
    12601 tgcggaagtt tctaagaacc ttcgcttgat ccttgagcgt aaaggaatga ccatcttgac
    12661 tggtactaaa ctgcaagaaa tcattgagga aaatggtcaa cttcgtatca aggttgaagg
    12721 aaaagacgat atcatcgcaa gcaaagctct tctttcaatt ggtcgtatgc cagaccttga
    12781 aggtattgga gaggttgagt ttgaattgga tcgtggttgt atcaaggtca acgaatacat
    12841 ggaaacttca gttccaggca tttatgcacc aggtgacatc aacggtacta agatgttggc
    12901 tcacgcagct ttccgcatgg gtgaagtttc cgctgaaaat gcccttaaag gaaatcatgc
    12961 agttgccaaa ttgaatttga ctcctgcagc catctacact ctccctgaag tagcagcagt
    13021 aggtttgaca gaagaacaag cccgtgagaa atacgatgtt gccatcggta agtttaactt
    13081 tgctgctaac ggtcgtgcta ttgcatctga cgcagctcaa ggtttcgtaa aagttatcgc
    13141 tgataagaaa tatggagaaa tccttggtgt acacattatt ggtcctgcag ccgcagaatt
    13201 aataaacgaa gcatcaagca tcatcgaaat ggaaatcact gttgaggaaa tgctgaagac
    13261 catccacgga cacccaactt actctgaagt gatgtacgaa gcgtttgcag atgttctagg
    13321 aatggccatc cattcaccta agaaaaaata aaacgaagat agattagact ggaaggttat
    13381 ttccagtctc tatcatataa agtaaaggga tatcatgaaa tacattatca atcattcaaa
    13441 tgacactgct tttaatattg ccttggaaga atacgccttt aaacaccttt tggatgagga
    13501 tcaaatcttc ctactttgga ttaacaagcc atctatcatt gttggtcgtc accagaacac
    13561 tatcgaagaa atcaaccgtg attatgttcg cgaaaatggt attgaggtag ttcgccgtat
    13621 tagtggtggt ggagctgttt accacgattt aaataacctc aactacacga tcatctccaa
    13681 agaagatgaa aataaggcat ttgacttcaa gagcttctca actccggtta tcaataccct
    13741 ggctcaactt ggggttaaag ctgagttcac aggtcgtaat gaccttgaga ttgatggtaa
    13801 gaagttctgt ggcaatgccc aagcctatat caacggccgc atcatgcacc acggttgctt
    13861 gctctttgac gttgatttgt cagtcctcgc aaatgccctt aaggtttcaa aagataaatt
    13921 tgaatcaaaa ggtgtgaaat ccgtccgtgc ccgtgtaact aatattatca atgaattacc
    13981 aaaaaaaatc acagtcgaaa aattccgtga tttactcttg gaatacatga aaaaagagta
    14041 cccagagatg actgaatacg tcttttcaga agaagaattg gccgaaatca atcacatcaa
    14101 ggatactaag tttggaactt gggactggaa ctatggtaaa tcacctgaat ttaacgtccg
    14161 tcgtggaacc aaattcacta gtggtaaggt tgaagtcttt gctaacgtta ctgaatcaaa
    14221 aatccaagac atcaagattt atggtgactt ctttggtatt gaagacgttg ctgcagtaga
    14281 agatgtcctt cgtggggtga aatacgaacg cgaagatgtt cttaaggcgc taaaaaccat
    14341 tgatatcaca cgctacttcg ctggtattag ccgtgaagaa atcgctgaag cggtagttgg
    14401 ataaatcaaa aagaagttgg ccaactaacc aacttctttt tttgatattt atttacataa
    14461 tttaaaatac gtaaaatcat aaactatcca gagcattctt ttgttcatca ctaacaatat
    14521 gggtatagag gtcagtgact tgtgtgctag catgtcctag ttggtgactg actaaaactt
    14581 gtgatttagt cgcatcatag agcctagttg ctagtgtatg gcgcagttta tggggtgtta
    14641 cacgcacttt aaaatcctct gagtatttag caaccatttt ctcaacgcta gaagcatcga
    14701 tacgattagg aacacctctg tagagagtta aaaaaagggc tgtatctgtt ttttccgttt
    14761 tatagcgttg attccgaatg gccagataat tctctaaata aggtttagca aaagcagcga
    14821 cattgactga gtcacgtttg ccaccttttc gagtaacatc aataaccatc atttttagat
    14881 tgagatctct tagatctaga ttaacagctt cagataagcg aacaccagat gccaagagaa
    14941 gggcaataat ggctaaatct cgttctttat ttttgttgaa tgatgagaga gctcgatttg
    15001 aaagctgttg tgggtgctct tgatcgatat aagttagaaa accttctgtt tcatcaccta
    15061 gaaagagttt ttgcttgata ttttcagctc tggcagcaag ggtttctttc tttttcttgg
    15121 ttgaaacttt tttcattaca ttacgataga aataaggttc cccctgatcg ttttcaacct
    15181 cctcggttag atacttgtaa agactagaaa gtgctgataa ggttcgattg atagttgtct
    15241 gtgaaacacc ttgttttgtt gtattagcat tcagcaaggg acgttcacgt agataaagga
    15301 taaaggattc catgtctttc ttagacatat tttccaaaac tgataaagga atatcggata
    15361 ttttatcagc gtttgaaata ccagactcca aaacccagct gaaaaatcgg tcatattcct
    15421 taaggtattc gtacagggtt gtaaaactgt agggcacagc cagcttagat tggtagtatt
    15481 ccagaacata ccagggcatg agttgtttta gtttgtcgat tcgttccagt aaaatctcac
    15541 gtttcatgta ttttctccat aagtaagtat actagtagta tagcatagac ttgtgtattt
    15601 ttcaagaaaa ttatagtttt tcagaaagat gttataggag tttttcaaag tgataaaaag
    15661 acttagacct acaaacaaaa cagaataagg aaaataatga aaatctcacc cactaaactt
    15721 ctgttaatac tacataactg aagagctata taaggagcta tgagatacaa aacacattgt
    15781 ataatagatt gaaactagaa tagtacatct ggacttctaa aacattgcta gaaattga
//
LOCUS       DAVHSI010000044        14959 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.045, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000044 DAVHSI010000000
VERSION     DAVHSI010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14959
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.045"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            140..1003
                     /locus_tag="VVR21_001729"
     CDS             140..1003
                     /locus_tag="VVR21_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU6055547.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAKQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(1292..2683)
                     /gene="argH"
                     /locus_tag="VVR21_001730"
     CDS             complement(1292..2683)
                     /gene="argH"
                     /locus_tag="VVR21_001730"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU6055548.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAHHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TIGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(2712..3909)
                     /locus_tag="VVR21_001731"
                     /pseudo
     CDS             complement(2712..3909)
                     /locus_tag="VVR21_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(3926..4732)
                     /locus_tag="VVR21_001732"
     CDS             complement(3926..4732)
                     /locus_tag="VVR21_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU6055549.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(4939..5580)
                     /locus_tag="VVR21_001733"
     CDS             complement(4939..5580)
                     /locus_tag="VVR21_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055550.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(5577..7685)
                     /locus_tag="VVR21_001734"
     CDS             complement(5577..7685)
                     /locus_tag="VVR21_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU6055551.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(7737..8024)
                     /locus_tag="VVR21_001735"
     CDS             complement(7737..8024)
                     /locus_tag="VVR21_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU6055552.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            8450..8770
                     /locus_tag="VVR21_001736"
     CDS             8450..8770
                     /locus_tag="VVR21_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU6055553.1"
                     /translation="MQRLEVYKNYQRLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(8822..9409)
                     /locus_tag="VVR21_001737"
     CDS             complement(8822..9409)
                     /locus_tag="VVR21_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU6055554.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            9651..10322
                     /gene="sdaAB"
                     /locus_tag="VVR21_001738"
     CDS             9651..10322
                     /gene="sdaAB"
                     /locus_tag="VVR21_001738"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU6055555.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKE
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            10331..11203
                     /gene="sdaAA"
                     /locus_tag="VVR21_001739"
     CDS             10331..11203
                     /gene="sdaAA"
                     /locus_tag="VVR21_001739"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU6055556.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            11225..11857
                     /locus_tag="VVR21_001740"
     CDS             11225..11857
                     /locus_tag="VVR21_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEU6055557.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     RDIKFDMLGARETGIQKLPVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            11907..11984
                     /locus_tag="VVR21_001741"
                     /pseudo
     CDS             11907..11984
                     /locus_tag="VVR21_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12161..14011)
                     /locus_tag="VVR21_001742"
     CDS             complement(12161..14011)
                     /locus_tag="VVR21_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6055558.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLTFLFYQLMIGFWGLNASISRYSKITDFMKIFFGATASSILS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDAKKKGQRLGGIPVLGSYDNLSELAKRHQIER
                     VIVAIPSLDPLEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIREIQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(14097..14927)
                     /locus_tag="VVR21_001743"
     CDS             complement(14097..14927)
                     /locus_tag="VVR21_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6055559.1"
                     /translation="MSEKQKISVLMSVYIKENPTFLKDAIESVQNQTLKPSELVLVED
                     GPLTPELYQVLDQVETESEIPVKRYPLEQNQGLGLALRQGVLQCQYNIIARMDTDDIA
                     VPDRFEKQLQLMEKDKLDLLGGHIAEFIDNPDEIVSYRRVPTQHADIVAYQRMRSAFN
                     HMTVMFKKDMVLKAGNYEDGLYMEDDLLWLNMIAAGAKTGNLDQILCQVRVGAGMFER
                     RGGLRYLKLYRQARQRMLKRGQISYMEYAKSVAIQMIVALCPGFVRQFIFMKLLRKSK
                     "
BASE COUNT         4534 a         3335 c         2654 g         4436 t
ORIGIN      
        1 ttaagctcat tttaaaatta cgttaacttt tttcacaaat ttatttcgac tttctttttt
       61 actttttaca ttgctatgat acaatatttt taacaagatt ttattgtttg ttaacttttt
      121 tcacagaaag gagaaaatca tgcgttatga tttcggaaag gtctataaag aaatacgtga
      181 gtcaaagggg ctgacccaag aagaggtctg tgggggtgtt ctctcaagaa ccagcttatc
      241 aaaaatcgaa agtggcaaga caaccccaaa atatgaaaat atggaatttc ttctccgtca
      301 aatcaatatg agttttgaag agtttgaata tatctgtcaa ctttatcaac caagtcaacg
      361 cacagagatt atgcaaacct atctcaatat gcgttccatt atcgggacca gcgatcttgt
      421 caatttattt caaaaatgcc aagactacct caagacccac cacgatctcc ctatagaaga
      481 aatcagagat atgcttgaag ttgttattta tctccgtcaa cacggggcag gggaactatc
      541 aaaacacgca aaacaggttg tcaaaaaact ttggaaaaaa attgaaaaac aagatacatg
      601 gtatgagagt gatctaaaaa tcctcaatac cattcttttc agttttccca ttgaatacct
      661 ccatctcatc actggaaaaa tattgcaacg cctagaagtc tataaaaact atcaacattt
      721 atatgacttg cgaatgacaa ttctattaaa cctttccaca ctctatctat acaatcaaga
      781 taaaaacatg tgtaagcaaa tctgctacac tttactggag gacgccaaga ataagaaaag
      841 ctacgatagg ctggctatct gctatgtccg tattgggatt tgtacagacg attctaaact
      901 tatccaaaaa gggttctccc ttctggagct aaccgaggaa acttctatgc tgtctcatct
      961 caaaaaagaa gtagagatct attaccaagc gaaggaaaga taaaaaagcc gagggatttc
     1021 ctcgactctt tacatattat ttgttcgtta gttcttaata ccagccattg ttaagccaga
     1081 agtttttagc tctgccaagc cacatagtgt gtttactact atgtgtccat gtcaccatga
     1141 atcgccgaac gatttaacga gaaagtatga cttttacgtt tatcccaact caattatgac
     1201 atttttttca aaagtcaata tatctcactt tttcaacgac aagaaagagg ctgccaatcg
     1261 accaacctct tattctgaac ccatcactcc atcacttttt agcttcattc gctttcttag
     1321 cgactgcaat ctggtattcg acttggtcaa accctgtgcc tcccaaggaa tttcgtcttt
     1381 gaacagcagt tttaggttgc aagtagacat agatatcctc ggtaatgaga gaatgatagg
     1441 tttgtaattc ctccaaagtc caatcttgaa gatttttagc agacttgata gagtctagca
     1501 ctaatcttcc cacaacctca tgagcttctc taaatggcaa gcctttccct gccaaataat
     1561 ctgccaactc agttgcattt gaaaagtcct tctctgttga ttcttgcatt ttttccttgt
     1621 ttacctgcaa actagataac atacctgcca acacatcgag ggaatttaaa atcgtttcga
     1681 ccgtatcaaa cattccttcc ttatcttctt gcaaatcctt attataagct aaaggcaagg
     1741 acttcatgac tgtcaacagt ccaaacaaat gcccataaac tctgccagtc tttcctcgaa
     1801 tcaactcagc catatctgga tttttctttt ggggcataat agaggaacct attgtaaacg
     1861 tatctgacaa ggtaatgaat tggtactcaa aactacacca attaatcatt tcttcgcaaa
     1921 aacgactcat atgcatcatg agtatgctgg catttgatag aaattctaag ataaaatcgc
     1981 ggtcactaac agcatccaaa gaatttgtat aaggttgctt aaactccagc aaatcgctag
     2041 acaattggcg atcaatgggg aaagtcgttc ctgccaaagc tgccgcacct aaagggcata
     2101 ggtctgtatg cttctggtta aattcaaaac gttcactgtc tctttgaaac atattgtagt
     2161 aagccatcag gtggtgggca aaactaatag gctgggcatg ttgcagatgg gtatagcccg
     2221 gcatgatcgt cgccacatga ttttccgcca agtctaataa aacaccctta agatgagcca
     2281 gtttatctag gacatagcct agttgttcct tgagatacaa gtgcatatct gtcgcaactt
     2341 ggtcatttcg agaacgagcc gtatgtaact tccctgcaag gggaccaatt ttttctgtca
     2401 gcaacacttc catattcata tgaatatctt cgtttgcgat atcaaagtca agttgacctg
     2461 cctctagctc ttctaaaagc tctttcaagc ctacttgaat cttttctgac tcctccaaac
     2521 tcaaaatgcc cgtctgaccc aacatctgaa cgtgggctaa agaaccaatc acatcaaatt
     2581 tagctaattt ctggtcaaaa gatatactcg caccaaagcg ctctacccag tcttcgacag
     2641 taccttcaaa gcgaccaccc cataattttg tattcttagc catatcacat ccacctctct
     2701 atccaatcgt cctatttggc gcttttttga acctcagaat gaaccttggt tggaagtccc
     2761 cataactcaa taaagccaac agccgcatct tggtcaaagg tatctgcact agtatacgtc
     2821 gccaaatttt catcgtaaag agaatttggt gatttccgag ccacgacctg agcactcccc
     2881 cttatacagt ttgacttttg cagtcccatt gacaactttt tgagtctctt taatataagc
     2941 aatcaaggct tgtgtagccg aactaaacca caaagcatta taaatgagat ttgataattc
     3001 attttctatg attggtttaa aatgagccac ttctctcaca agcgtcaagt cctcaatttc
     3061 cttatgagct gtcagcaggg tcactgcacc tggacactca tagatttctc ttgatttaat
     3121 cccaaccaag cgattttcca cgtggtcaat ccgtccaacc ccatgttttc cagctatttc
     3181 attgagtttt tgaatcaaat ctgccaattt taacacttct ccattgaggg aaactggaac
     3241 accttcacta aactcaatct caatgtattc tggcatatct ggagcttgct ctggagaagt
     3301 tgtgatgcca aaggcttctt ctggagcctg attccatgga ttttccaaaa taccacactc
     3361 attggcacgt ccccaaagat tttggtcgac agagtaggga ttgtcaaggt cagcaggaac
     3421 aggcacccca tttttcttgg cataataaat ttcttcctcc cgagaccatt tccattcacg
     3481 aactggagca atcactttta aattgggatc caaggctgca atcgatactt caaaacgtac
     3541 ttggtcattc cccttaccgg tacaaccatg agcaattgta gtcgctccta tctgatgcgc
     3601 tatttcaacc aattttttag aaataagagg gcggctcaag gcagatacca aggggtactt
     3661 ttgttcataa taggcatgtg actgaagagc cactagcaca taatctgtag caaattcgtc
     3721 cttgacatca atgacataag attcgactgc cccaaccttg agagccttat catggatgaa
     3781 gtctaagtct ttcccttcac ccacatccat acaaactgaa acaacatcat agtctttctt
     3841 taaccaggta atagcaactg atgtgtccaa accgccagaa taggccaaaa ttactttttc
     3901 tttactcatg ttcttttcct tctttctatt tttcaatgga tgctttaaag gcatcctcaa
     3961 tgagtttgtc taattcccca gactccttca acttttgaat ggttttatcg actgcctctt
     4021 tcaattcctt gctatctttt ttcatggcta ccgcgtagga atcatcttgc tctttttcaa
     4081 aattgaggtc tgcgattgct aaatcaggat tattttccac aaatcccttg gaaacaggtt
     4141 cttcaaagat aacggcatcc acttgtcctg attttaaatc tgtgattaaa ttcccatttt
     4201 taggcagaga tacgagggaa gaattttgta gcaaatcttt cgccatcgtc tcttgaatcg
     4261 aacctttctg cgctccaacc tttttctgcg ccaagtcgtt tacagactga taagtagtca
     4321 agtcagattt tttgacaatg agtttatttt ttgcagtata gtagggaatg gaaaagtcaa
     4381 acaccttgct ccgttcatct gtcttagaaa cacctgatat ggcaaggtcg gcttttcctg
     4441 attgaacact agccagtaca ttatcaaaac tcatgggaga tagttccaat tcgacaccta
     4501 gttctgttgc gatagccttg gctaattcga tatctgaacc cacaatctga tttttcccat
     4561 caaccacttt ttggtattca aatggagcaa aatctggatt gagggctaca accaattttc
     4621 ctttggactt gatggcttca attccagccg attgattgtt gctacaagca aatagtaggg
     4681 ggagcatcac taaaccaaac atcgtcatca acaccttctt catcttattc ataacaaagt
     4741 ctcctttatg tttattcttt ttggttgtat aaataatact cccatactca tcctttgtca
     4801 agcctaaatt gaaaaaattt tcaatttgaa acaaaaaaaa cctagaaata ctacataaaa
     4861 tgtcattcct aggcgtattt atgctatttt tctctggaaa acatgagtat tcagccagtc
     4921 aaaaggagct gaatgaactc attttccctc gcccaattca atgacacgat gacattgttg
     4981 ggctacataa gcatcgtggg tcacaataat gactgttttc ccttctcgat tcatctctaa
     5041 gagaaacttc aagaccaaat ctctattttc aggatccagc gaacctgtag gttcatcggc
     5101 taaaatcagc tggctgggtt ttaagatggc tctagcaact gcaattcgtt gttgttcgcc
     5161 cccagacaac tcggagaccc tttgatgcaa agtagctgac aaacctactc tctctaaaat
     5221 ctcttccacc tttttgagct tgtctttctt aggcaatttc acatatttca gcgccagcat
     5281 gagattgtac tcgaccgttt catcatcaat cagggcaaaa ttttgaaaca gataagagat
     5341 atgttcacgg attattgttt gcgacttagc agaattaacc gctagatttg tctgaccaaa
     5401 aatctcatac cgtccgctat aatcaccatc tatcaaaccc aataaattta acaaggtcga
     5461 cttcccacta ccactcttac caacaatagc taccaaatcc ccctgatcaa tcctgagaga
     5521 taagttatcc aaaatcactt ttcccccaat ggttttggta atatttttca actcaatcat
     5581 aagatgcccc ctttcaataa ctctactaga cttcttttct ccatcctaga agctaagcct
     5641 agcacaaata gtatatccag acatgtaaaa cctgcaaaca gtagaagtgg taagaacgca
     5701 tgggcaaaga aaatcaagac tagaagaggg aaactatagc ccagcaagag cagaacgagg
     5761 agaggacggt agcgatcgac cagtttccac cccataaact tcttggtaat gatatccctg
     5821 cgcttcaata agaaagttgt tactagtaag aagtaggaaa tcatcatgct aaggagacca
     5881 aacaaagcaa agagtaggtt aaaattccga acagcatctc tataagaatc cactttctct
     5941 tgttgaatgg cttgaataga tgaaaatttt aaataatttc catctgacaa tttctcaact
     6001 aactctgtaa tctctttttg atgttgaacc gtattttcaa ttttaatcgg attatttaag
     6061 ccagttgttg acagggaggc tttctcatcc cacatcatat cagaatcatt gaccaagcta
     6121 ataattggat tggagagatt ttcctttcgc ttatcactat atgggaaaaa tgaccaatct
     6181 ccttcataat aggcaatctc gacatccatc tcctctatcg ttcgtttttg ctgctcttca
     6241 tacttcatcg aatgaaaggc aattaacttc cccaagagct gatttttatc ttcttcacct
     6301 ttcgtacttg ctggcatcaa aataactttt ttaataccgg tatctggtag cttgaatccc
     6361 ttgctcttta gaaaattgcg attggcatag taaacatcca ccgtatctgt taactgatat
     6421 tgctgaatct gttctgattg gacaaaattt tttacaggaa gactgctact ctgcacatag
     6481 cccgcctgcg ttttttctac caaatcctga taaaatcgat agaaataatc tgtagatttc
     6541 cctgaccctg ctagctcttc ttgccacaga ttatcattga gtttgaaggt ttctaaggtc
     6601 aggtaattac cttgacttac ccactgttgc tgataagcaa gttctttgtt ttcttgttct
     6661 aaacttctgc ccaccccaat cagtaaggcc gtcagtaaaa tagttgtccc tattttcatc
     6721 acataattga agataagacc aaatttgaaa gatgaaaaac ctttcagcag agagctgatt
     6781 gtcatttttt ggattaagag gtaagtcaac caactgataa agagataaag ctgcaacagc
     6841 aaaaaatgag acaaccacag cataggaaac aaatcttttg gcttataatc aagcaagaaa
     6901 aacacgccta gattgatcac aagagcccca cctaggagga ggtaaaggtt gccttttaca
     6961 acatcagcta aaacagccct atcttgaaaa ccaagtaatt tttgtacccc aactcttttc
     7021 atctccatca tcggttgata cactgtcact aacacaagaa gcaaaatagc caagacaaaa
     7081 acaatggcag ataaaagcaa atctcgattt atgacttcca ctgcactttt gtaggtcggc
     7141 tctagcaagg tagcctggtc tatcttgaaa aaatcgctcc atttctgtac aatcctatcc
     7201 ttgtccatct cttgtgtaga agttatcgta tagcgaccat ttaaactacg agatgtatcc
     7261 ttgatatagg tttgaaaagt cataagctga ataggtttgg cttttagaaa ggtcggaatc
     7321 gtaccaagtt tattggaaat ttctttatta ctatagactc cttcaccatc tgtggtaaaa
     7381 tcaagagaag aaatcccaaa ctcttggtag gggaaggtat ctttatcaaa aacaccagac
     7441 ttgaccacct catcaccact gtctgttttg atgatggaga ctttatactc ctttgataca
     7501 tcctcaaaaa atcgaagaac agacgctgca ggttcgttaa tatctttcaa atacaaatcc
     7561 aaagaatcta cagtctttcc catttcttga atccgaacca cttctcgtgt atagtttaca
     7621 ttaaaaacaa aaaaagtggt acacagaagc aggagtaaca tacagaaatt actgattttt
     7681 ttcataaaag tgcctccact acagttttcc ctctccaaat aggagaggga agaattttac
     7741 tcaaatccat agaaatattc cattcctgtt ggcggaatct tggtgaggga agctctagcc
     7801 catgcctcag gttttgcata atccttagag gttctacccc catgtctaac agttgctgta
     7861 tgatatcgag tagaatgtaa gtaatcagaa tatccaaaag ttcctgtcca acctactcca
     7921 tagttccatt gaccaccctc aacccatact gctaaagcat ttgtagtagc aagtatacca
     7981 cataccatta aagatgcaac accaatttta actaattttc tcatgattta tttctcctat
     8041 tatcgagagc tgttccgtaa aaacagctat agtaatttat caacaagtat cgtagtccat
     8101 tggactcacc ttccttctat ctcatttcat ttttaaacaa cgaacttact cttaactaga
     8161 agaatagttc tcttctgtat caggtctttg aacaaccaga gtagtattaa tcacactcta
     8221 actattactc aagaatcagc ccaataaaca acatggatag cgctttcaaa tttttaaact
     8281 cttatcccat ccttttatct atataataag tgaaaatata ataactgtca agtaatcgaa
     8341 gtaaatttta taaaaaaaat tacaagccaa atttgtaaag tttacactaa gccgctaggg
     8401 caatcgtcta tcagaatgtc cgtttatttg tcaataatcc gagaaaatct tgcaacgctt
     8461 agaagtctat aaaaactatc aacgtttata tgacttgcga atagcaatcc tgctcaacct
     8521 ttccacactc tatctataca atcaagataa aaacatgtgt aagcaaatct gctatacttt
     8581 actggaggac gccaagaata agaaaagcta cgataggctg gctatctgct atgtccgtat
     8641 tgggatttgt acagacgatt ctaaacttat ccaaaaaggg ttctcccttc tggagctaac
     8701 cgaggaaact tctatgctgt ctcatctcaa aaaagaagta gagatctatt accaagcgaa
     8761 ggaaagataa aaaagccgag ggatttcctc gactctttac atattatttg ttcgttagtt
     8821 cttaatacca gccattgtta agccagaagt ttttagcagc agtccatgaa ccgtaacgtc
     8881 ctgcaacgta ggcatctgct acacgttctt ggttttcagc tgagtagtca ccgttcaggt
     8941 atgaatctgt taattggtaa cgtccgatat aacgtccatt tgtagctgta tagctaccac
     9001 ctgattcttt ttgagcgatc cattctttgg cttctgcttc agatccgctt acagttgaaa
     9061 caactgtttc acttactact ggagtttctg ctactggagc tgaaacagtt tcatcttgag
     9121 cggctggtgc cgcataagta gctggcgctg gtgttgcaac aggcgctaca gggccatcga
     9181 taaccaactc ttgatcaaca taaatcaaat gaatgttatc aatgtggttg ttttctgcca
     9241 atttttcaac tgttgtgttg tgagtttcag cgatttctga aagtgtatca ccttctttaa
     9301 cagtgtaagt tgatgattct tgagcagata caaatgatgg agcaaatact gcaaacaagg
     9361 cagcaactcc tgcaagagtt gctttaatct ttttagttat tgatttcata ttcgaaaatt
     9421 ctccttcttt ctatagttct atcataccct ttaaatatta ccgtttcttg acacttttat
     9481 gtagaaatat tacaaaatta ttttttattt ccctaaataa ggtgtttttt gtcataaaag
     9541 atactatttt tatgctattt gaggtattag aaaggttttc atccacaatt aaagccaagc
     9601 ccctcattct ttgatataat agagataaga atttttataa ggggaaactg atgaaatcac
     9661 ttcgttttca atctgtcttt gatatcatcg gaccagttat gattggccca tctagtagcc
     9721 ataccgctgg tgctgttcgt attgggaaga ttgtctcttc catttttgat gatactccga
     9781 cagaagttga attccaactt tttaactcat ttgccaagac ctatcgtggt cacggaacag
     9841 acctagccct tgttgcaggt attttaggaa tggatacaga tgatcctgaa attccaaata
     9901 gtctggaaat tgcccacaag cgtggtatca agattgtctg gaccattcag aaagaaagca
     9961 atgcccctca ccctaacacc actaaaatta ctgttaaaaa tgcccacaag accatcagcg
    10021 tgactggtat ttctatcggt ggaggaaata ttcaggtaac cgaactcaat ggttttgccg
    10081 tctctctcaa tatgaataca ccgactatca tcatcgttca tcaagatatt ccaggtatga
    10141 ttgcccttgt tacagaggcg ctttcccgct atggtatcaa tatcgcccag atgaatgtca
    10201 ctcgtgaaaa agctggtgaa aaagccatta tgattatcga agttgacagt cgcaactgtg
    10261 atgaggctat cgaagaaatc cgaaaaatcc ctcatctcca caatgtcaat ttctttaaat
    10321 aggaggaagc atgttttatt ctatcaaaga attggtcgag caagcagatc tggactttca
    10381 aggaaatgtc gcagaactca tgattacaac agagtttgaa ttgaccggtc gcgaacgtga
    10441 agaagtcttc cttctcatgg aacgcaatct ggaagttatg aaagcctctg tccaacttgg
    10501 cctcaatgaa aataaatctc gtagtggcct gacaggtgga gatgctgcca aattggatca
    10561 ctacatcgaa aacggaaaaa ctctgtcaga ttatacgatt ctctcggctg cccgaaatgc
    10621 catcgcagtc aatgaacaca atgccaaaat gggcttggtc tgtgccactc caaccgctgg
    10681 aagtgctggc tgtctgccat ccgttctcac tgctgctatt gaaaaattag acctcagcca
    10741 cgagcaacaa ttggatttcc tctttgctgc tggtgccttt ggactagtca tcgcaaacaa
    10801 tgcctccatc tcaggtgctg agggtgggtg tcaagctgaa gttggttcag cctctgctat
    10861 gagtgctgcc gccttgactc tggctgcagg tggaacacct tatcaggcca gtcaagctat
    10921 tgcctttgtc attaaaaata tgctaggcct catctgtgac cctgttgcag gtttggtcga
    10981 agttccctgt gtcaaacgta atgccatggg agctagcttt gctttcatcg cagcagacat
    11041 ggccttggca ggtatcgaat ctaaaatccc tgtggatgaa gtgatcgatg ccatgtacca
    11101 agtaggagca agcatgccaa ctgcctttcg tgaaacagct gaaggtggac tcgctaccac
    11161 ccctactggt cgtcgcctcc aaaaagaaat tttcggagaa taagcttatc aaataggaga
    11221 aaccatgacc tctatcacag cgattttttt cgatttggat ggaaccctcg ttgatagttc
    11281 tatcgggatt cacaatgcct ttacctatac ctttaaagag ctgggggtgc ctagccctga
    11341 tgccaaaact attcgtggtt ttatgggacc acctctcgaa agtagttttg cgacctgcct
    11401 gtccaaagac caaatttctg aagccatgca gatatatcgt tcttactata aggcaaaagg
    11461 catctatgaa gctcaactct ttcctcagat tatagacttg cttgaggagt tatcaagcag
    11521 ttatccactc tacatcacca cgacaaagaa tacatctact gctcaagaca tggcaaaaaa
    11581 cttggaaatc catcatttct ttgatggcat ttatggttct agccctgaag caccccataa
    11641 ggcagatgtc attcaccaag ccctgcagac acatcaacta gcaccagaac aagccatcat
    11701 catcagagat atcaagtttg atatgctggg agctcgagaa acaggtattc agaaattgcc
    11761 cgtcacttgg ggatttggag agcaagcaga tctactaaac tatcaacctg attatatcgc
    11821 tcacaaaccc ttagaagttt tggcgtattt tcaatagcat agactgggta acaattccat
    11881 ttcagaagaa aatgaagtaa tactcaatga aaatcaaaga gcaaactagg aaactagctg
    11941 cgggctgctc aaaacactgt tttgaggttg cagatagaac tgacgaagtc agatcaaaac
    12001 actgttttga ggttgtggct agaactgacg aagtcagtaa ccatacctac ggcaaggcga
    12061 cgttgacgtg gtttgaagag attttcaaag agtataagtc tctacataat aaaacgcata
    12121 ttaccaaggt tgttaacttg ataatatgcg tttttctttt ttattcaatg tgggttgttt
    12181 gattagcaaa ggcgataata gcttgcttca attcatctcc actgagagtg cggaactctc
    12241 caatcttttg attgatggat tctaaaggca tgacattaac cttaccaacg aaaatcttat
    12301 ccataacttg attgtcaacg agttcggttg ataccaagag ttcttcgtag agtttttcac
    12361 ctgggcggat tccaacttca acgattggaa tttcactttc agtgtggcca cttagaagca
    12421 ccatcttctt ggccaagtca taaatcttga ctggtttgcc catatcaagg ataaagactt
    12481 ccccatcttt ggcataagca ccagcatgga taaccagacg gctagcttct ggaatggtca
    12541 taaagtaacg ggtcatgcgg aagtctgtca ccgttacagg cccaccttca gcaatctgac
    12601 gttcaaagac tggaatgaca ctaccacggc taccaagaac attcccaaaa cgaactgcac
    12661 agtaggttga ttggctacgt tggttaaagc cagtgacaat caactccgcc acgcgcttgg
    12721 ttgctcccat aacatttggt ggattaactg ccttatctgt cgaaatcata accatcttag
    12781 acactttagc ttcatcaaca gccttagcaa cattgtaagt tccacggata ttgtttttga
    12841 aggcttcttt tggattgcgc tccatcatag gaacatgctt gtgggctgcc gcatgataaa
    12901 caatagcagg tttgtactgc tcaaagactt gcaacaaacg atcatagtct tgaatgtccg
    12961 caatcacagg tacataatca atcccttgga tctcacgaat taattcatga taaacaaggt
    13021 agattgagtt ttccccatga ccgagcaaga caatgcgttc aggattgaag cgactaactt
    13081 gacgacagat ttcagaaccg attgaacctc cagctcctgt gactaagatg gtcttacctg
    13141 tcagttctgc acccagacgc gattcgtcaa gacggatttc ctgacgaccc aaaaggtccg
    13201 taatatcaat tttttggaag ccagtacctg cttggtgaag gccctgaaca acagtttcaa
    13261 ccttaggcat cttgtaacat ttgacaccca gcttattaca catctgcaag atacgctcat
    13321 attctaacgg atccagcgac ggaatcgcaa cgatgacacg ctcgatttga tggcgtttgg
    13381 ctaattcaga cagattgtca taagagccta aaacagggat accaccaagt ctttgaccct
    13441 ttttcttagc atccttatcc aaaataccaa caagttccaa ttcactagtt ggatgttggt
    13501 agctatccat aaagagagcc ccaccatcac cagcaccaat caagaaggta cgacggtgtt
    13561 ctccatcacc actacctttt ttgcgtctgg agtagattaa ctgccaagta atccgtggca
    13621 ataaaatcaa gaaggtactc aacaagataa agagaatgat gaaacggatg gagaagagtg
    13681 gcaagaaggc atagcagata ctatatgaca ggatactgct ggcagtcgca ccaaaaaaga
    13741 ttttcatgaa atccgtaatc ttgctgtaac gactaatact cgcgttcaag ccccaaaaac
    13801 caatcatcaa ttgatagaac aggaaggtca aactcgtata gataatgtag tcaacaggtg
    13861 ctggattaat cagcccataa aataaaatat aagatacaat gatggaaacc accatactga
    13921 aaatatcaaa tattccccag aaaacctgct tttgttgttt atttaaaatt tccaccagat
    13981 caatcacata atctgtgagt tttttattca tagaaattta ctcctcctta aaagaactgg
    14041 atagttatat tgttattata acacttttta tccagtttac gatttgctac aatcttttac
    14101 ttgctttttc gtaacagttt cataaaaata aactgtctga caaatcctgg acaaagggca
    14161 acaatcatct gaatggcaac actcttggca tactccatgt aagaaatttg ccctctcttc
    14221 agcatgcgct gacgagcctg acgatagagt ttgaggtaac gcagtccccc acgacgctca
    14281 aacatccctg ctccgacacg aacctgacac aagatttgat ccagatttcc agtcttggct
    14341 cctgcagcaa tcatattgag ccagaggagg tcatcttcca tataaaggcc atcctcatag
    14401 ttgcctgcct tgagaaccat gtccttcttg aacatgacag tcatgtggtt aaaggcactt
    14461 ctcatccttt gataagctac aatatctgca tgttgagtcg gaacacgacg gtaagaaaca
    14521 atctcatcag gattatcaat aaattctgca atatgtccac ctaataggtc aagcttgtcc
    14581 ttctccatta actgaagctg tttctcaaaa cggtctggaa cagctatatc atccgtatcc
    14641 atacgagcga tgatattgta ctgacactgc aaaacaccct gtcgaagagc cagacccaaa
    14701 ccttgattct gctcaagagg atagcgtttc actggaattt cagactcagt ctccacctgg
    14761 tctaacacct gatagagctc aggtgtcaaa ggcccatcct caaccagaac caattcgctc
    14821 ggtttcagag tctgattttg aacactctca atagcatcct ttaaaaatgt cggattttcc
    14881 ttgatataga ccgacatcaa tacgctgatt ttttgctttt cagacacagt ttttctccaa
    14941 tgtatagatt tccttccac
//
LOCUS       DAVHSI010000045        13963 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.046, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000045 DAVHSI010000000
VERSION     DAVHSI010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.046"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            83..280
                     /locus_tag="VVR21_001744"
     CDS             83..280
                     /locus_tag="VVR21_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU6055560.1"
                     /translation="MAGKITKKSSSMGIIANVFAGLVGAYAGQSLLGSWGPSIAGMAL
                     LPSIVGAAIVITVVSFFTGRK"
     gene            364..930
                     /gene="amaP"
                     /locus_tag="VVR21_001745"
     CDS             364..930
                     /gene="amaP"
                     /locus_tag="VVR21_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU6055561.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            942..1112
                     /locus_tag="VVR21_001746"
     CDS             942..1112
                     /locus_tag="VVR21_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU6055562.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1151..1759
                     /locus_tag="VVR21_001747"
     CDS             1151..1759
                     /locus_tag="VVR21_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU6055563.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1790..1993
                     /locus_tag="VVR21_001748"
     CDS             1790..1993
                     /locus_tag="VVR21_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU6055564.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLHKEEK"
     gene            complement(2066..2512)
                     /locus_tag="VVR21_001749"
     CDS             complement(2066..2512)
                     /locus_tag="VVR21_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055565.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYIMKKGR"
     gene            2582..3241
                     /locus_tag="VVR21_001750"
     CDS             2582..3241
                     /locus_tag="VVR21_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU6055566.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(3293..4444)
                     /locus_tag="VVR21_001751"
     CDS             complement(3293..4444)
                     /locus_tag="VVR21_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU6055567.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESVRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTLKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(4459..5188)
                     /locus_tag="VVR21_001752"
                     /pseudo
     CDS             complement(4459..5188)
                     /locus_tag="VVR21_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5417..5518
                     /locus_tag="VVR21_001753"
                     /pseudo
     CDS             5417..5518
                     /locus_tag="VVR21_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(5490..6266)
                     /locus_tag="VVR21_001754"
     CDS             complement(5490..6266)
                     /locus_tag="VVR21_001754"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU6055568.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQV
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(6259..7482)
                     /gene="trpB"
                     /locus_tag="VVR21_001755"
     CDS             complement(6259..7482)
                     /gene="trpB"
                     /locus_tag="VVR21_001755"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU6055569.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(7460..8059)
                     /locus_tag="VVR21_001756"
     CDS             complement(7460..8059)
                     /locus_tag="VVR21_001756"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU6055570.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(8046..8813)
                     /gene="trpC"
                     /locus_tag="VVR21_001757"
     CDS             complement(8046..8813)
                     /gene="trpC"
                     /locus_tag="VVR21_001757"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU6055571.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGTVMISVLTDEVFFKGHLNYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKKLYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(8810..9814)
                     /gene="trpD"
                     /locus_tag="VVR21_001758"
     CDS             complement(8810..9814)
                     /gene="trpD"
                     /locus_tag="VVR21_001758"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU6055572.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(9825..10391)
                     /locus_tag="VVR21_001759"
     CDS             complement(9825..10391)
                     /locus_tag="VVR21_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU6055573.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(10388..11749)
                     /gene="trpE"
                     /locus_tag="VVR21_001760"
     CDS             complement(10388..11749)
                     /gene="trpE"
                     /locus_tag="VVR21_001760"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU6055574.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(11884..12039)
                     /locus_tag="VVR21_001761"
     CDS             complement(11884..12039)
                     /locus_tag="VVR21_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055575.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            complement(12251..12328)
                     /locus_tag="VVR21_001762"
                     /pseudo
     CDS             complement(12251..12328)
                     /locus_tag="VVR21_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12936..13937)
                     /locus_tag="VVR21_001763"
     CDS             complement(12936..13937)
                     /locus_tag="VVR21_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU6055576.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         4045 a         3029 c         2508 g         4381 t
ORIGIN      
        1 gaaattgatt ttttgatatt aaaataaaaa aggagggtag gcagtgttgt gatcaattat
       61 tgctggaggt cttattggtc tcttggcagg taaaatcact aaaaaaagta gttctatggg
      121 aatcatcgca aatgtattcg ctggtttagt cggggcatat gcaggacaat ctcttttagg
      181 tagttggggt ccatcaatcg ctggaatggc tttgctccca tctattgtag gtgcagcgat
      241 tgtgattact gtagtgtcat tctttacagg tagaaagtaa acttttcgcc agtaaagtta
      301 gcaaactatt tttaaatcaa tgacgggaaa aatagtttaa atgttaaatc gaaaggattg
      361 tatatgtcaa aagcaaagaa aatatgtttc attattttct gtattttaat cttgacaatt
      421 ttccttcctg ttttgataga ttatcatcaa gttagtgatc taggtattca tctacttagc
      481 tggagacaga actccgtagt tgaattctat cttgctagat atgtcttttg ggggacagtg
      541 gttctatcaa ctttagtttt attatccatt ttagttgtga tgttttatcc taaacgttac
      601 ttggaaatcc aacttgaaac taaaaacgat acattaaaat taaagaattc ggcaatcgaa
      661 ggttttgtta gaagtttggt gagtgatcat agattgatca agaacccaac tgttcatgta
      721 aatttacgaa aaaataaatg tttcgttcat gtagaaggta aaattcttcc ttcagacaac
      781 atcgctgaca gatgccaaat aattcaaaat gaaataacta atggattgaa gcagtttttt
      841 ggtattgagc gtcaagtaaa acttgaagtt gcagtaaaaa attaccaacc aaaacctcaa
      901 aacaaaaaga ctgttagtcg tgtgaagtaa ggaagtaaaa aatggaatgg cttaaacaat
      961 atcgatatcc aattatcgct ggtctcatag gcgtatttct ggcttgtttg attgtctcct
     1021 ttggcttctt caaaacaata tttgtattga ttttaggagc actgggagtt gcagctggat
     1081 tatatatcga aaaaaactat atagataaat aaaaaaataa aaattactaa tttaattaaa
     1141 ggagtttcat atgtcaaacg aaaaaaacac aaacactaac gtagaaaaga aagatgctac
     1201 tgttgtagct cacgaaatca aaggggaact tacttacgaa gataaagtta tccaaaaaat
     1261 cattggtctt tcactagaaa acgtttcagg tcttttggga atcgatggtg gtttcttctc
     1321 aaatcttaaa gaaaaaatcg ttaacagcga tgacgtaaca agtggtgtta acgtagaagt
     1381 tggtaaaaca caagttgcag ttgacttaaa cgttattgtt gagtaccaaa aaaatgttcc
     1441 agctttatat tcagaaatca gagaaatcgt atcttcagaa gttgctaaaa tgactgactt
     1501 ggaaattgtt gaaatcaacg taaacgttgt cgacatcaaa actaaagaac agcatgaagc
     1561 agactcagta agccttcaag atcgcgtatc tgacgttgct gaatcaacag gagaattcac
     1621 ttcagaacaa ttcgaaaaag ctaaatctgg tcttggatct ggtttctcaa ctgttcaaga
     1681 aaaagttagc gaaggtgtag aagctgttaa aggtgcagca aatggtgtag tatctcacga
     1741 aaacactcgt gtaaactaag ataaaataaa tataacagga gaaattatca tgtcagtaga
     1801 agaaaaatta aatcaagcta aaggttctat taaagaaggt gttgggaaag ccatcggtga
     1861 tgaaaaaatg gaaaaagaag gagcagctga aaaagttgtt tctaaagtaa aagaagttgc
     1921 cgaagacgct aaagacgctg tagaaggtgc tgtagaaggt gttaaaaaca tgcttcataa
     1981 agaagagaaa taaggtttag actttatata ttcttttaag accaaaaaat caggaaaagc
     2041 cttggaatca aggctttttt gatgtttatc tccccttttt catgatgtat tttcgtacag
     2101 gtgcttcaac catttgaacg atttcaaatc cttctttttg gtaaagattc tgagctcttt
     2161 gatttgcctc gaagacattt agagaaatac tatctatatc ttcattttca aaggccaaac
     2221 taacaaattt ccttaaagcc tggctaccta agtcttgctc ctgcttctgg gggttgataa
     2281 aaaatctccc gatatgaaga ttgctgtctt ctagcctgat tttctggata agtcccacaa
     2341 actcttgttc atcaaagatt gaaaagactc cttccaaggc ttgaagggtc agtagaaaag
     2401 gaatccttgg tcccatccat tgttcttgaa agactttgcc taaggagttg gaccattggc
     2461 atacgagctg agcgttttct atactcacct tttcttcaaa acgaattgtc atcttttcct
     2521 caccatctta tctatgtttc tccattatac tatttctccc attttttacg aatagataag
     2581 tatgattgat ttttattttt ttctcgtcgg gagcattctc gcttcctttc ttggtttggt
     2641 cattgaccgt tttccagagc aatccattat cagttcagcc agtcactgcg attcctgtca
     2701 gactcgcttg cgtcccttag atttgattcc gattctctca caggtcttca atcgctttcg
     2761 ctgtcgctac tgcaaagttc gctatcctgt ctggtatgcc ctctttgaac taggcttagg
     2821 actcctcttt ctgctttact cttgggaatt gctttccttg gggcaagtcg tcctaatcac
     2881 cgctggtttg accttgggta tctacgactt tcaccatcag gaatatccct tactggtctg
     2941 gatgactttc cacctaatcc taatagcttc ctctggctgg aatctggtca tggtctcctt
     3001 cctcatactt ggaattttgg ctcattttat tgatatccgc atgggtgcag gggatttcct
     3061 ctttttagct tcttgtgctc tcgtctttag cgtaacggag ttactgatct tgattcagtt
     3121 cgcttctgcg acgggtatcc tggcctttct cctgcaaaaa aaaaaggaaa gacttccttt
     3181 cgtgcctttc ctcttacttg ctacttgttt gattattttt ggtaagctac tgcttgtttg
     3241 ataaattcca atttctgcca tatgtccttc atgaaattat ttcacagtta aattataaat
     3301 tatttctttt gtacaaaggg atgatgttat caaatcgatc tgttcttcta tcttcttgat
     3361 actgatcaaa aaatttcatt tcgactgaaa atatttcgct tataaactgt aaacgaatac
     3421 tttgtttaga cattatagtc gctagactga ctagatgatt actcaaaacg acgtccagaa
     3481 tactctttac tttgcttggt tttttaacaa aaatttgatc atccaaaggt tcaatcattt
     3541 tgtaaccttt ttgcgcaatt tgacgataaa agtaagaatg ttgctttaga gtcaataatc
     3601 ctaacttaaa agctcgatac tctaaagcct gtatcgaaac attcaaatcc gacttcaata
     3661 aaatataact atcaggattg ctgacacgct tgccaaccct ctcttcaaat ttgactaaaa
     3721 actcttcttt tggcaataaa aaacatgatg caaaataatt tgcttcttgc tccaaacgat
     3781 cgccatcttc attcatatct ttatatttat gtaaaagaat atgtcctagc tcatgagcta
     3841 agtcaaaatt tcgacgtaca gatgatttat tcgttcccaa cacaatataa ggtcttccca
     3901 attttgacca tgcgctataa gcatcagctt ggccattaat taatcgttcc acgatataga
     3961 tgcctgaacg ttctaattta taaagcaaat catgattatc ttttgaaata cctaattttt
     4021 ccctggcata aagagccaat tcctcaatgg attctccctt atgataagat tcactcacta
     4081 cattacttaa gtcatgaatt gtaatattag gtataattac aaaactttca aaataatcaa
     4141 tcaaactatc taccttatgt aaatacatag tttgaatatc tattgttttc cgtgttgcta
     4201 ggtctgcatt tctaaaggca attacagaag aatcaaatcg aacgctctct tcttcctgtt
     4261 caaaataagt taaatcaaca tgaaattggt tggccaaatg cattttggtt gataatttag
     4321 gtttcgtttc gttggactca aactgccaaa tggcttgttc cgttaaatta attctctgag
     4381 ctaattctgc tctacttaaa ccatttaaca gccgtaattc tttcaatacc cgaccattaa
     4441 acatttacat actccttact acttttgacc ttcttgtttt tctattcttg gaataatttc
     4501 aaaatcttct gtttccgata attctgaaaa attaggaata tcttgatatt tagcttcttc
     4561 gaaatggtac gaacttgatt gaatatactc agacaaatct tgaatcaagt gtaactgacc
     4621 agttcgtgca tcaggcataa caacatctac agatataata ttgttttctg agtccgcctc
     4681 ataagttaaa atcataaatt tttcgatatt cgaattttta gtagcttgtt caatttcttg
     4741 aatcatttca tcagaaacta actccatctg aattggaaag gaatgactat cttcatcatt
     4801 tttgtaggaa gaatgttgat taagataaag tgtattcatc tgagcatatt caaataagta
     4861 gccactctta tttttttgta ccaaaggaaa ttggttcgta agtcgcttct taccctttat
     4921 aattaacaat actttcccat atttttctgt gtttgtttca aattctaaat atccaagtct
     4981 gtcctgctaa ttgtaattta tactcaaaca aatctgctga tgcaaatgca gtatcaatat
     5041 gattaggtcg cgtccatgca taaccattcg acactatcat tgtctctctt ttttctagac
     5101 gttcatctac ataatctttt tgccctttca tcaaagtatc tacaattttt tgtgcctcaa
     5161 gcgaatcaaa gagatcctga ttcaacataa ttcttcctcc tccaaatact ttttaatgaa
     5221 ttatatcatt ttcttaaaga aattactaca ataattagct ttttcttaaa gttctgtgtc
     5281 agagtaattt agaaaattat atcttctata gtaaaatcaa ttaaaaactg aacaaattta
     5341 ttgggaaatt caaatcgctt tctgaaaata ttttaggaac cgtagtgtaa tattccagat
     5401 tcaattcact ataaaactag cctttctcct gcaaaagaaa aaggaaagac ttcctttcgt
     5461 gcctttcctc ttacttgcta cttgtttgat tatttttggt aagctactgc ttgtttgata
     5521 aagtcctgaa tcggctctcc ttggtggaga gcttttacta ttttcgaacc gacgataaca
     5581 ccatctgaca ccgcattgaa gcgttccaga tcgacttgac tagatacacc aaaacctgtc
     5641 aagactggga tgtcggccac ttgatgaagt tgcgccaagt gcttgtccaa atctgcacgg
     5701 taattgcctg atttccctgt taccccattg atggcaacgg catagacgaa tccctccgcc
     5761 ccttcaatca actctttctg gcgctcaatt cctgtggtca agcttactaa aggaatcaag
     5821 gcgatatctg tatctgccaa aaatggttct acaaagttgg catgttcatg aggcaggtct
     5881 gggataatca agcccttcac agctgtatca gccagatctt tgacaaagtt ctccacaccg
     5941 tactgaaaga gggggttgaa gtaggtcatg atgaccagtg gaatctctgt ttcaatggtt
     6001 ttcaaggttt caactaaagc ctgggtagag gtcccgtggg ctaaactgcg caagccagct
     6061 tcttcgataa caggtccatc tgcaacaggg tctgaaaagg gaatacccac ttcaattgca
     6121 gagacaccca aatcttctaa aaagtgaatt gtttcagcaa gaccatccaa acctttttcg
     6181 tggtcaccag ccatgatata gggaacaaaa attccttttc cagctgcttt aatagcattt
     6241 aatttttttg ttagtgtctt aggcatgagc ttctcccttc tttgctgcat ctgcttccaa
     6301 gcggtccttg acttgaacca catccttgtc cccacgacct gataggcaga caatcataga
     6361 cttttctggt ccaagttctt tggccaattt caccgcaaaa gcgatagcat ggctagattc
     6421 caaagctggg ataatccctt ccacacgaga caagagttgg aatccttcca aggcttcttc
     6481 gtctgtcaca gggacatagc tggcacgttt aatatcgtgg tagtgagaat gctctggacc
     6541 gataccagga tagtccaaac ctgctgagat agagaaggct tcaagaattt gaccatgggc
     6601 atcttggagc acatccatga gggaaccgtg aaggacacct ggacgaccct tggtcaaggt
     6661 agctgcgtgg tgctccgtat ccacaccaaa tccagccgct tcagctccat acatggctac
     6721 tgactcatct tctacaaagg gatggaagag accgatggca ttcgacccac caccaacaca
     6781 ggctactagg gcatctggca gattttgtcc tgtcaagtca cggtactgtt gtttagcctc
     6841 tcgaccaatg acactttgga agtcacgaac aatttctgga aatggatgag gccccaaggc
     6901 agaaccaagg atatagtggg tatcatctat attagccacc catgaacgaa gggctgcatt
     6961 gaccgcatcc ttgagcacgc gcgaaccatc tgtcacggcc tcgaccttag ctcccaaaag
     7021 ctccatacgg aagacattga gggcttggcg tttgacatct tcctcaccca tgtagatggt
     7081 acattccatg ttaaagaggg ccgcagcagt tgcagttgcc acaccgtgct gaccagcacc
     7141 agtttctgcg ataattttct ttttacccat gcgtttggca agccaaactt gtcccaaggc
     7201 attgttaatc ttgtgggctc ctgtatggtt aaggtcttcc cgtttgagat aaatcttggc
     7261 tccgccgata tgctgggtca agttttttgc gtagtaaagg ggagtttcac gtcccacgta
     7321 ctggcgcaaa agctggttta attcctcttg gaaacttggg tctgcctgac tttcacggta
     7381 ggccttctcc aactccaaaa ctgctgtcat caatgtttct gggacaaaac gtccgccgaa
     7441 ttttccgtaa aatccatctt tatttggttc ctgatatgcc atgctttacc ctctctataa
     7501 atcttctaat cttttcatga tctttttgtc catctgtctc cactccgctc gatacatcta
     7561 ctgcataggg agtaaaatgt tgaattgctt ttactacatt atcttcatta aggccacctg
     7621 cgataaagaa gggctgtgct agtccagtcg tatccagttg accccaatca aagggctggc
     7681 cacttcctgc cacaggggca tcaaagagta gataatctgc ctgagaattg gggacatgcc
     7741 catttccatc tacctgcaca gcctgaatac tggcacaagg caaattctca aataaatcat
     7801 ctgccacctg accgtgaact tgaaccaagt ccaagccaac tttgtcaatc gcttccagca
     7861 gttctacccg acttggtgaa acaaatactc caaccttttt cacatctgca ggaataagct
     7921 ttgccaactc agctgcctct tctaaagtca cctgtctttt actaggtgca aagacaaaac
     7981 cgatatagtc ggctcctgct gaaacggctg tttccaccgc ttctttggtc gatagtccac
     8041 aaattttaac ctttgtcaat ctgcaactcc ttgattctct gggccacatt ttctgcctgc
     8101 ataagagctg tccctaccaa aattccgtta aagtatgggg ctagtcgttc cgcatcctgc
     8161 cctgtgaaaa tggcagattc agaaatgtaa tagcgacctt cctcaaagta aggggctaaa
     8221 tctacactgg tctgcaagtc gacctcaaag gtagtcaagt tgcggttgtt gaccccgata
     8281 atctcagcac caagtctgtg ggctacctct agttcagcta gattgtgagt ttccaccaag
     8341 acttccagac caagctctgt cgcgtagtca tacagtttct tgaggcgttc ttcggacaag
     8401 gctgccacaa taagcaagat aactgtcgca cctgcattgc gagcgcggat gatttgcttt
     8461 tcatctatga taaagtcttt gttgagcgtc ggaatctcta cctgactgga aatctcccgt
     8521 agataattca aatgcccttt aaagaaaacc tcatctgtca acaccgaaat catcactgtt
     8581 ccgttttctt cataagtctg ggcctgttgc acaatatcca catcgagatt gatatctccc
     8641 aaactagggc tagctttctt gacctcagcg attacctgca agcggtcctg atgattcttc
     8701 aaaaattctg ccaagcgata ggtctggcgc agaggctgga tttgctccag cttcatctgc
     8761 tccacctcac gcgccttctg ctctaagatt cgtgctaaaa attcctgact catttttggt
     8821 actcctgtaa cagtctgagt ttttcaaggg ccttgcctct agcaatcact tgacgggcca
     8881 aggcaactcc ttccttgatg ctatcaatct taccattagc atagaaacca agaccagcat
     8941 tcaagactgt cgtttccaag aatggacttg cttcgttttt cagaacgcta agcaaaattt
     9001 ctgcattttc ctgagcattc ccaccacgaa tatcttccat agcatagcct tccattccca
     9061 aatcctctgg agtaaagctt gacaagctga tttcgccatt ttcaagaagt gcaatcttgg
     9121 ttgttccgtt caagccagct tcatccaacc cttctggtcc agcaaccacg atggcacgtt
     9181 tgcgacccat atttttcaaa acctgagctg tactttctag gagttctgga cgactaattc
     9241 caagaagctg tgtttctaaa gccattggat gaatcagtgg accagtcaag ttcataatcg
     9301 ttggaattcc caattccaaa cgagctggca tgatgtattt catagctggg tgcatatttt
     9361 tagcgaagag aaagacgatt ccagttttat caaagacctt acctagttca gctggtttga
     9421 ggtcaagatt gattcccaag gcttcgagga catctgcgga accagattta gaagatatcg
     9481 agcggttacc gtgtttggcc atgtgaatac cgccaccagc caagacaaag gctgcagttg
     9541 tggaaatatt aaaactgaaa gacttgtccc cacctgtacc acagttgtcc atggcatcat
     9601 gaatctcagt tggaatatgc tgggcatgtc ctctcatgac ttgggcaatg gctgtgcgtt
     9661 cttcaggtgt ttcccccttc atcttaagag ctaagaggag agaagcaatc tgcgcttcag
     9721 ttacacgccc agttacgata cgctcaatga catccgtcat ttccacacct gataaatttt
     9781 caaattttgc tagtttttca ataatctctt tcatcctagt ttcctcactt tacaacctcc
     9841 tcgataaaat tccgaataga agacaagccg tctggcgttc caatgctctc tggatggtac
     9901 tggaagccat aaatcggtag gtttttatgt tgaatcccca tgatggcttg gtcatcagtc
     9961 gaacgagctg tcacttcaaa gtcttctggc atttcctcaa tcaaaatact gtgataacgc
    10021 atgaccgcac gtccatcctc aataccttga tacaaaacag atggcgcttc aaagttgata
    10081 ttgctctgtt tcccatgcat gacttttgga gccaaaccta gcttaccacc aaagacttct
    10141 gcaatggctt ggtggcccaa acaaatccct agaatcggct tcttgcctgc aaaatcacga
    10201 atcatgtctt ccatctttcc agcatcaact ggccaaccag gaccaggaga aaagaccaga
    10261 ccatctgctt tttcagcttc ttcatacagc ttggaatcat catttctcag aacctgaact
    10321 tctgcaaaat tcccaatgta ttgggccaag ttataggtaa aagaatcata gttgtcaatc
    10381 aataaaatca tggtcttagt tctccaattc tagtcataga ttttgctttg ttaatggttt
    10441 cttggtattc gttttgggcg atagagtcgt agacaatccc tgccccagcc tgcacatagg
    10501 ctctttgatt tttgagaatc atggttcgga tggcaatggc caaatccata tcacccgtcg
    10561 cagacaagta gccgattgct cctgcatata cgccccgttt ttccgtttcc agttcataga
    10621 tgcgtctcat cgcccgaatc tttggtgctc cagaaacggt tccagcagga agtgtagctt
    10681 tcaaggcatc catggccgtg agttctgcaa gcaaacgccc cttgaccacg ctggtcaaat
    10741 gcatgacgta gcggaagagc tccaccttca tatacttagt aacttggaca ctggccgttt
    10801 cagagatgcg gccaatatcg ttacgcccca agtctaccaa cattcgatgt tctgctgttt
    10861 ccttctcatc agagaggagg tcagtcgcca aggtcttgtc ttcttcatcc gtagcccctc
    10921 ttggtcgcgt ccctgcaatc ggattggttg tcacgatgcc atttttgaca gaaactaaac
    10981 tttctggact agctccgatg atttgataat ccccaaaatc atagaaataa aggtaattag
    11041 aaggattagt cacgcggaga tttctgtaga agtcaaatgg atttccagta acttctgctg
    11101 agaaacgctg gctgagtaca cattggaaca tatcaccatt acgaatcaag tcacgagctg
    11161 tttctaccat tacctcaaac ttatgtggag cgatatgcgg tttgaagtca agtggtgata
    11221 aatccaagtc ttcaaattca tttggagcag gaatgcgtaa ttcctcaagc acttggttca
    11281 aggatttttc caaggcctct tgactgcgct cactatagag agcatcctct atgacatgta
    11341 tcttctcctt cttgtggtca aagaccatat agctctcata gacaaagaaa tgcatgtctg
    11401 gcgtcccaat tgtatcctca gggatttgac caatttcttc ataaagcgaa atcatatcgt
    11461 aacccacaaa accaatggct ccaccaccaa acgggagctc tgagtggtgc tgactcttat
    11521 gaatcacttc ataaaggaaa tccaagggat cccgatcaat cacttgacca ttttgataga
    11581 gaactccatt ttcaaactta atctcaaaaa ctggattata ggctaggata gaaaaacgag
    11641 ctgtttcctt gtctctcgga atactctcta aaataacctt gtgttgcccc tttaagcgca
    11701 tgtaagccaa gattggtgat aagacatctc catgaatgat tcgttccatt gtaatttccc
    11761 tttcagttct acttatagtc cgtagcgact gtatgaaaaa tccccacgca aaataacttg
    11821 cgtgaggacg aaattcgcgg tgccacctca attataggat ttctcctatc tctcattcct
    11881 gtctcagata tctcctgtaa caggctgtgc gataaagggc actcccttga gaatgatgtt
    11941 ttcttctctc gtttcagatg aacccaactt tacagctttc tctgcttgtt tccagcaacc
    12001 acaagctctc tgtgagagaa agaactgtaa tttttccatc tattattttt tagcttctag
    12061 gtagtctgca atcgcagcta ggtccttgcc tccacgacca gagacattga tgaagagatg
    12121 ttcatctcgg tacaccttta tactcttcga aaatctcttc aaactgcgtc aacgtcgcct
    12181 ttccgtaggt atggttactg acttcgtcag ttctatctgc aacctcaaaa cagtgttttg
    12241 agctgacttc gtcagttcta tccacaacct caaaacagtg ttttgagcag cctgcggcta
    12301 gtttcctagt ttgctctttg attttcattg agtattacta gcttttttcg tattagtcca
    12361 gcctttttgt ttgcttttag tagtaggcaa ggagctgtag atagaactca agttcatcaa
    12421 agcgacttaa ggccctaata aaagataaac caaacgacgg atagaaaaaa gcccacacac
    12481 agaatatact tccgtgtgag ggcgttggta acgcggtgcc acctcaatta taaagggact
    12541 atccctttac atctctgcct tgtttaacaa caagctgcac tgtaaggtgt gcgcaccgaa
    12601 ttttcattgt ttcaaattca ttttcaaaat cagcccactt tcactacttc caaccaccta
    12661 ttcacaatca ccacaggctc cctgaagatc aaaaatagtt acttttctga tttgttgaac
    12721 ttattttaat actttgtttt ttctttgtca agactttttt acgatttttt tgaaaatatc
    12781 attcgaatgt gaccatgtct tccttagatc gaacatgaac atgtcccact tgttagaaat
    12841 tggatccaac tcaatagaaa ctgaatggag gctaaacaga acttatttta gaacactcca
    12901 tcttttccac taggattttc aagaattaaa caatactaga aactctgtct cctaacaaat
    12961 ttaggagaaa cttcaacaga tgtgacactt tcccctttaa taattgctaa aacaccttct
    13021 atcatttctt tagccaattt aacataattg ggagcaattg tagacaaagc tggagtataa
    13081 tactgagaaa taggaatatt atcaaatcca atgatagaaa tatcatctgg aataagaatt
    13141 cctttctcat agcacgcacg aatcaagccc tgaacctttt catctcctga aacaaaaata
    13201 atgtccggat aattttgggt agtcaagtgc tgcattgcat aagaataaac tgaatcaatt
    13261 gtagataagc cataaatgac ttttaaatcc ataaagtaat ttttatcatt cagaaaagaa
    13321 cgcacacctc tttcacgatc cttattaaca tgggattctc ctcccataag caaccacata
    13381 tttttaaatt tttcttcagt tacagctttc atcatatcat aagtagcttg aaaattatta
    13441 ttagatacat agactactcc agacgtttga gattcaccga aaacaagaaa aggcatatgg
    13501 ttcttcttta aatactgaat tctgatatca tctacacttt cataaaaaac aataacacca
    13561 tctactaggc tacctgtgct tgatataatt gaattactaa ttgtatcctc ctctccaaag
    13621 tactcaacta tagcattaac accaaattct ttacacgtcc gtaacacttt atctaacagc
    13681 gtatgaaacc aaattaaagg aaaagagtcg atttttttta cagaaatcaa tatatttata
    13741 gcttcttttt tagttaaatt ttttgcatac gcatttggaa tatacgacaa ttcctctata
    13801 actttttgaa tcgcttgata agtttcttct ttaacattta ctccaccatt aataactcgt
    13861 gaaactgttt ttggagaaaa acctgataaa cgtgcaatat cataaatagt tacctttttc
    13921 ccatttatat ttttcatttc agtcctccat tacgaacatt cta
//
LOCUS       DAVHSI010000046        13293 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.047, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000046 DAVHSI010000000
VERSION     DAVHSI010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.047"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(325..1491)
                     /locus_tag="VVR21_001764"
     CDS             complement(325..1491)
                     /locus_tag="VVR21_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU6055577.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHYLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            complement(1504..2243)
                     /locus_tag="VVR21_001765"
                     /pseudo
     CDS             complement(1504..2243)
                     /locus_tag="VVR21_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(2265..3089)
                     /locus_tag="VVR21_001766"
     CDS             complement(2265..3089)
                     /locus_tag="VVR21_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6055578.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQHIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(3226..4440)
                     /gene="thiI"
                     /locus_tag="VVR21_001767"
     CDS             complement(3226..4440)
                     /gene="thiI"
                     /locus_tag="VVR21_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU6055579.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(4449..5591)
                     /locus_tag="VVR21_001768"
     CDS             complement(4449..5591)
                     /locus_tag="VVR21_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6055580.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDKKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFEIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            5729..6157
                     /locus_tag="VVR21_001769"
     CDS             5729..6157
                     /locus_tag="VVR21_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055581.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPTTPTSENNTQ"
     gene            complement(6308..8533)
                     /locus_tag="VVR21_001770"
     CDS             complement(6308..8533)
                     /locus_tag="VVR21_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6055582.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDITTVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMESRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(8697..10649)
                     /locus_tag="VVR21_001771"
     CDS             complement(8697..10649)
                     /locus_tag="VVR21_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6055583.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(10646..11557)
                     /gene="pfkB"
                     /locus_tag="VVR21_001772"
     CDS             complement(10646..11557)
                     /gene="pfkB"
                     /locus_tag="VVR21_001772"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU6055584.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(11554..12294)
                     /locus_tag="VVR21_001773"
     CDS             complement(11554..12294)
                     /locus_tag="VVR21_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6055585.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPYSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12456..12543
                     /locus_tag="VVR21_001774"
     tRNA            12456..12543
                     /locus_tag="VVR21_001774"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12490..12492,aa:Ser,seq:gga)
     gene            complement(12726..13073)
                     /gene="ssrA"
                     /locus_tag="VVR21_001775"
     tmRNA           complement(12726..13073)
                     /gene="ssrA"
                     /locus_tag="VVR21_001775"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         3890 a         2996 c         2543 g         3864 t
ORIGIN      
        1 acaacctcaa aacagtgttt tgagaaacct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt attaatagac ttgtttggta tcttgaaaac tatatcgtat aggtgtcgtc
      121 atggatcctt ttagctgatt taaggatacg caaacacaat actatgactc aattgaaata
      181 ttaaaattca atttctgacc acctaatcct gcttcaaata gttatcgaac aagttttatg
      241 atagctacct tgttgggatg ctcttatttt ttatcagaca aaacaaaagg attaagggag
      301 ttaatttcct taatccgata gttcttattc ttgacgttgt ccgaaatctg caatcatctg
      361 ctccatttct tgtcgactcg gagtggtcag catatacagg taatctcctt gaagttccgc
      421 gaaggcagct ggcatgactt ttttaacctt gaactgctgg ctatatttgg caagcaaatc
      481 ctcttctgaa taaacatagt gagcatttgc acggcgagaa gtagccaaac aatactgagt
      541 ttcaaagtct gacgccggga actcctctcc tgcgacaata gctgcatagc cacgataaag
      601 gtccaagtaa tgagcaaagt tataaacatc aatggtaaaa ccacctgcag ggcggttatt
      661 gtactcgatg gtaatataat cgtccccctc acggaagaac tcaatatgga aaaaccgttc
      721 tttcatacca aattctttga caattgcttc cccatacttg cgcagtttag gatccatatc
      781 cttgagcaca taataagaat tgtccatctt ataaatcatg aggtcaagcg gtgtataggc
      841 gtagtcaaag gttgttgaga agacaatctt tccatccttg tccacgagcc cgtcaaaggt
      901 acagatttcg ctggaagtga caaatttttc aaagaaataa agggttgaat ggtcccattc
      961 ttgcttgaag tgattgatat cgtcttctgt ctcaagttta aaggttgcgg ctgctcccac
     1021 tccattatca ggtttggcaa tcattggaag accgatttct ttcactgctt gatcaacatc
     1081 tgcttccgtc ttgataacag ctccaggtac cacaggaaca cctgcttttt tgaaaagttt
     1141 cttcatttca gacttatatt tcgtcttttt gagatcctct ggtttggcac caaaaacatt
     1201 gaattgttct ctgagtgttg cgtctagctc aagccagtat tcattgtgag actcgatgcg
     1261 gtcaattgga ccatgtttat aaaagagaaa agcaactgca cgtttgactt catctatgtt
     1321 ctcaagatta tcaacacgaa aatactcggt caagctattg cgcaagggct catccaattg
     1381 ctcgtaagac tcttgaccaa ttcccaagac tgtgatgcct ttattagcta gttcgatggt
     1441 aaactgttga aagttttgtg gatagtaggg agaaataaca aggtaattca taggtaactc
     1501 cttttataaa tagagattac cgaggaaata aggcatttgt ttacgccacc attcccagtc
     1561 atgggcgaca tcatgtcccc attcagcaaa ccaggctgga atttgtttct tgtcaaaggc
     1621 ttctttgagc ttgtaaaagg atgacaaacc atcttgttcc caggctccaa gccccgtaca
     1681 cagcacaatc tctgcctgac ggtaacggtc aataaaccag ccgtcgtttt ggttccaaat
     1741 ataatctact ggcgagtttt ggtaaatagc atcatcgttg tagtaatcac cgataaagaa
     1801 acgtgcgtcg taaacaccac tgagagcaat cactttggta aagacatctg gatgctggag
     1861 gaagaaattg agtgcatgat aggctcccat agagcaacct gtcgtcatca tgccataaaa
     1921 ccaacctgtc ttgtgcttga taaaagaatg gcctcctcaa tcacataaca ttcgtaggca
     1981 cggtgcattt ccgcttggtc atgagcattt ttccaagtag ccaaccagct ctcactatcc
     2041 acactagata gggtaaagaa ctggacacgg ccttcctcga taaaggaagc acaggcatca
     2101 atcatgccaa aatcatagta ttcgttgtga ctaccacctg atgaagcaaa gaccacaact
     2161 ggaatcccac catgtccata acggttaagg tacatttcac ggttaggatg accactccag
     2221 tggctaagat gttcaatatg catttcgttt tttcctttct taacttacca tttttctgca
     2281 aaaaatctca gacaatctgg tagattttct gaccaaggga tttcactatg gatggcacca
     2341 gactgaactt ttagcacaag attatccaga tgtactcccc ctgctatcaa atcatggtaa
     2401 tagcaaagcg acgagtcgat ataggcttgt ttgatattgc catccatcaa ggtcttgtct
     2461 gtatcatctg cttcttctgt tcctacatag atgaagatgt gctggtcagg cgatagtttc
     2521 tggcactcga tatagcggtt aaaggcttct tggtggagcc agtttgcaga tgaaaaaacg
     2581 cccaagcaac caatttggtc ttggtattcc aaaccgataa actgggtaat attgcctcct
     2641 agtgaggaac caatcatagc cgtatgctgg cagtctgctt ttgtacgata agtctcatcg
     2701 ataaaaggct tgaccacctc catgacaaac tcagcatact ccacaccctt accaccaaac
     2761 tgctgctctg ggataggaga ttcttggaac ttccaagccg catactcatt cattcgcccc
     2821 ataccatcat tgtcaatagc aacgacaatc atgcgactga tatccggatt tcgtttgata
     2881 gctggaataa tcttccatga atatccaatg aaagactctt tgctataaaa aacattttgc
     2941 ccgtcatgaa agtatacaac aggataggaa cggtctgtat ctttctcata atctttagga
     3001 agaagaatac gtacacggcg ctccttacct gtataaggaa ccttgagttt gtgttctttc
     3061 atttttagat aaaagtagga ttgattcatt gtcagaaaac tctctatatt caaaatttta
     3121 tatcattata tcatgaaaat agaaaaaagt tagtttttta cctgttttta gaaaaaaaaa
     3181 ctaacttttt ttactgattt tcgctattct tttggatttt ctgaattaga gtagattatc
     3241 aatcaagtca tcaacttcat ctttttcggc ttgaggtgtg atttcagtaa tcatgattcc
     3301 agccactgct cgctcaacca agccttcaac atccatacgc gcttcgtact gctccgcatt
     3361 cttaatttta ggatttgttt ttggacgatc tggtgcaaaa atggtacaac agtcttcaaa
     3421 cggttggatt gaaatgtcaa aggtatcgat ttcctgggcg atgtcaatga tttccaactt
     3481 gtccatggta accacaggac gaatgatggg agtgttggta acagcattga tagccttcat
     3541 actttcaagg gtttggctgg ctacttgacc tagactttcc ccattgatga taaccaaacc
     3601 atttcgtacc tcacgaatac ggtcagtaat ccgcatcata aagcgacgag ttagagtcat
     3661 caaataagct tctggcgctt tggctttgat ttcctcttga atctctgtga aaggcacctc
     3721 gataaactgg atatttccgc caaacttggt caatttacgg gtcaagtcct gcgctttctt
     3781 gagggcacca ggactagtat atggtggact agcaaagtga actgcctcga tatccacccc
     3841 acgcttaaga gcaagataac ctgctacagg tgagtcaatc cctcctgaca acatgagcat
     3901 ccctttacct gaagttccaa ctggcaaacc accagcccca cgaatggttt cataagaaag
     3961 ataggctgct tcttcacgaa tctccacctg aagattgatg tcaggacttt tcatttgaac
     4021 ttgcacattt ggaatggctt cgaatacagc ccctccaagt gtttggttga gttcacgact
     4081 atcaagttca aagttgtggt cgctacgctt gctagaaatc ttaaaggtca taccttcctt
     4141 gtagatgtcc cgcataatct cttggacagc agacttcaaa acttctacag atttttcaac
     4201 cttataaaca ggagaaaagt tttgaattcc aaaaacttgt ttgagagatt ctgcaactgc
     4261 tgtgtaatca gctccattga ggtaagcgtg ggcacggtcg cgatctgctg ttaccttaac
     4321 ttggggatag atagacaaaa cgtctgaaat attattgcga agtttattga tgaaacgcat
     4381 acgatttttg cccttggttg acagctcacc gtagcgaatc ataatttctg aatactgcat
     4441 gaatgctcct atcttacttt tctagtttga ttgtaaatta attttagctt ggtcaagaac
     4501 tgctcgacct gactcatatc attttcaagg tctagactaa gacgcacagc tgactgagcc
     4561 ttatccttgt ccactcccat agcaatcagg gttccggctg gtttcccagc cttggacgaa
     4621 caagccgagg tcgttgagat gaaaatatca tagtcttcaa aggcgtgaac aatgacctca
     4681 ccacgaacac ccttgatttc aaaagtcaga atatgagggg cgaagtcttc ctcatctgaa
     4741 aagacaaata tatccggata gtccagaagt gcttgacgaa tcactgcctt catctgccca
     4801 gtcttgctcc taaagatatc tagcttttcc atagataaac ggagagcctt agcggtcgct
     4861 gcaattcctg ccacattttc agttgtcgaa cggtaatcac gttcttgacc accacctgtt
     4921 aaaagaggcg taatcttctt gccagacttg atatagataa aaccaacacc acggattccg
     4981 tggaacttgt gaccagagaa agtcgcgaaa tccactcgtt ctgtcagata cttttcagtc
     5041 ggaatcttgg caagcgcctg aaccgcatca acgtggaagg aaatagttgg cttgtctgcc
     5101 aatagttttg aaatagcctc aatgggctga acagagccaa tttcattgtt aactgccatg
     5161 atggaaacga gggtcgtatc aggtcttatc aaatcttcta gcgcctcaac atccacaaat
     5221 cctttcttat caactggagc aaaatccact tcaaaacctt gagctttcaa ccagagggct
     5281 gattccttaa ctgctggatg ttcaatggct gatacgatga tgtgcttgcc aaactgggct
     5341 ttttcaaatg ctactccctt gatgatccag ttatcccctt ctgtcccacc agatgtaaag
     5401 aagatttcat cacttttctt accgattaaa tctgcaatct gttgacggga agcatctaaa
     5461 attcgtgttg cctggtctcc caaacgatgg agactagatg gatttcctaa aatttttgaa
     5521 gccacctgca tataggtttc aagggcttct ggatagggcc tggtcgtcgc cgaattatca
     5581 aagtaaatca tgtttctcac gctttctaaa atcactcctt ctattgtatc atgaaacgga
     5641 gcttgcgaca agaaagggca atttctcttt ttttaagatt tttttaaaga aacagagtat
     5701 aataagtcat aatcaaagga gagaatgtat gtctaactat cgtagaactt caaaaccgaa
     5761 aacagaacat atcaaaaaag gctttactgt ttttcaaaaa accattacta ctatcggtag
     5821 tatccttggt ttgattacag cgggtatcac gatcatgaac gccttggata ataataataa
     5881 aaatactaaa aaagaaccta cgacaagcca gacgacaacc tttgtcaaag aaattcaaaa
     5941 agaatcccct caggaaaata ctactccaaa taaggaaaat aacacttctc aagaaaaaac
     6001 acaacaagaa gaaacgccaa aatctagcgt caaggaagag aaaaaagaag atcagaaaac
     6061 agcaactcag gactctacta cacctgctac aagtaaacct gccactgaaa atgaaaaaca
     6121 gcccactact ccaacttcag aaaataatac tcaatgaaaa tcaaagagca aactaggaag
     6181 ctagccgtag gcagtacttg agtacggtaa ggcgaagctg acgtggtttg aagagatttg
     6241 cgaagagtat aaaagtaatc aatagccagt aaaatagctc cttccaacct tggaaagaag
     6301 ctatttttta ttgctgcaat acttttcttg gcttggtacc ttcagctgga ccaatgacac
     6361 ctgccatctc aagctcttcc atgagacggg tcgcacggtt aaatccaact gacaaacgac
     6421 gctgaatcat ggatgcactg gctttctgtg tttcgataac caaagactta gcttcttcaa
     6481 aaagcggatc accaccagca tctccatccg aaaattctcc ttcattttca gaaacctcac
     6541 ctggatcaaa actctcatcg tagtctgcat ctgcctgagc cttgatgaag ttcacaatgc
     6601 gctcaacatc gtcatccgag ataaaggagc cttggagacg aactggatga ttttcatcaa
     6661 tcggtttaaa gagcatgtct cctcgaccaa gaagtttttc tgctccattt tcatccaaaa
     6721 tcgtacggga gtctgttcct gatgaaaccg caaatgctac acgagatgga acattggcct
     6781 taatcaaacc agagatgaca tcaacagatg gacgctgagt tgcaagaatc atgtggatac
     6841 ctgcagcacg cgccttctgc ccaagacgga tgatagcatc ttccacttcc ttgctggcca
     6901 ccatcatgag gtcagccaac tcatccacaa tcacgacaat gagtggtagc ggaatttgct
     6961 tgtactcaga ctgggaattg aactcttcta ccttggcatt aaaacctgca atattccgaa
     7021 ctcccacctt ggcaaagagt tcataacggc tttccatttc atccacaacc ttttgcagag
     7081 ccttgctggc tttgcgtgga ttggtcacga ctggaatcaa gaggtgggga atatcattgt
     7141 aaacagataa ctcaaccatc ttgggatcga ccatcataaa tttaacttga tctggtctcg
     7201 ccttcatgag aatgctagca ataatgccgt taactgctac tgacttccct gaacccgttg
     7261 aacctgcaac tagcaagtgg ggcattttag aaaggtcaaa agctcttgcg gttccattaa
     7321 cagccttccc taaaggaatt tccaagaaat tttctgcttt cgtttgcgat tgttcccata
     7381 gttctcggaa agatacagtg gtaatatcgg agttaggcac ttcaattccg attagggatt
     7441 tcccagggat tggtgcttca atccggacat ccttggcagc caaggctaga gcgaggtcat
     7501 ctgatagatt ggaaatgcgg ttgaccctta caccaacagc cggcttgact tcatacttgg
     7561 tcactgatgg cccaatttcg gcccgttcaa ctgttacctt aataccaaag ctagcaaagg
     7621 ttgcttctaa gattttgata ttttctctga caattttctt ctctttagac tgatcttttg
     7681 gtttatctgg tgcaaagagt tgtaagcttg gaagtttgta ttcaagggct tctttggctg
     7741 aaaaatcgac ctgaacatct tcgtcatctg agtcatcttc ctgttcaggg aatttaagtt
     7801 cagcttgagg caggatgatt tctggttcca cccacttttc ttctggaata ggtggaagat
     7861 tttgaacagc ttcctctgtc agaatttcac ccgtttccat atcaacagga ggcaaatcga
     7921 gtaaggcttt ttcagtctct tcttgttcta atctagcctc tttctcagcc ttttggcgag
     7981 ctttttcttc ttgtttgaca aagcgttcct cttttcgacg ctcgtgccct tcccaccatt
     8041 tggcaaagcc tctactgaaa aattcagcaa tatcgtaaac agaccaaggg ctgactagga
     8101 gagaacccac taaaatcaag atagaaccaa taaagtaagt tccgatattt gaaaagagaa
     8161 aggctgttgg aatataaaga gcgaccccga tcaagccccc tccagcaaag ctagtcgttc
     8221 gaaaaccagt cagatctgtc acaacctgag ccatggtccc ttttagaacg gacttgtcca
     8281 aaccatattt ccaaaccaag taggcctcaa aaatcaagag taagccagca aatatggtga
     8341 aaaagccaga taagagtcct tcctgttttc gtatccactt gaaaaagaag agatagatta
     8401 ataggccgaa tatcgccaga taagctaggc tacccactag caagcgaatt aaattataaa
     8461 gggttatacc tgcagcccct aatttgaagg ctgcgaaaat caataaaatc gcaattccta
     8521 acgaaatcaa cattcgttga atcgcttctt ttctttccag ttctgcttta gacggtctcc
     8581 gtcttgttgt acttgtattc ttgtttgcca ttcttctatt ataccatatt tcacaggcat
     8641 ttcgggaaga gaaaaagact gcaccaaacg gtccaatctt ttcatttttc tattttttat
     8701 gcttgtggtt tgcgtaggta accataaacc acaccactta cgattgctcc taccaagaca
     8761 gaaacgaggt aaaggagagc atttgaagta agggcgataa cgaagattcc tccgtgtggc
     8821 gccatgagtt tgataccagt aagaccaacg agtccacctg ctactgctga accaaggatg
     8881 aagcttggaa tcgcacgagc tggatcagcg gcaccaaatg gaatcgctcc ctcagtgata
     8941 aatgacaagc ccatgatgat gtttgtcaaa ccagagttac gttcttcctt agtaaattta
     9001 tctttgaaaa gaagagttgc gacaaagatt gcaagtggtg gcaccattcc tccagccata
     9061 actgctgcca tggctacaga accacctgaa gaaacagttg ctgcaagcgt acctgtacca
     9121 aagacataag ctgctttatt aactggtcca cccatgtcaa cagccatcat tccaccaagg
     9181 acgataccaa gaaggacagc tgaacctcct ccaagaccgc ctaggaagtc attcatagca
     9241 gtgttgattg cagccattgg gatattcaca gctagcataa caaatcctgt caagattgtt
     9301 ccaagaagtg gcaatagaag gattgattta gcaccttcga gtgaacgagg aactttaacg
     9361 tatttcttga tggcaagaac caaggcacct gcgataaatc caccaacaag ggcacctagg
     9421 aaaccagatg agacacctgc aagagttgaa gttgcttcac cacctgcggc ataaggaatt
     9481 ttaccaaagg caaaaccttc tttggcaata gcaccagcca cgaaacctgc taccaaacct
     9541 ggtttttcag caatagagta ggcaacataa cccgcaaaga ctggaagcat caaaccaaag
     9601 gcagctccac caattttcat gaacatagaa gctaactcat ggtaagaacc aagattgcca
     9661 aggttttcat ttggaacact caaagcaccg tcaatcaaga aggcaagggc aatcatgata
     9721 ccaccaccga taacgaatgg taacatttga gatacaccac tcatcaagtg tttgtagaag
     9781 gcaccaccaa ggctttgttt ttcgttagag gctgttgcag cttttgcacc attagcggca
     9841 cggtagactt cagtatctcc tgaaagagcc aagttaatta gctcttctgt cttacggata
     9901 ccgtcagcaa ctggacgatt gatcaatggt tttccatcaa atcgatccat ttcaacggcc
     9961 ttgtctgctg caatgataat agctttagcc ttacggatat cttctgcagt tagttgattt
    10021 ccaacaccgc tagcaccgtt ggtttcgacc ttgataccaa cccccatttc agcagctact
    10081 ttttgaaggg cttcttgggc catgtaagtg tgggcaatac ctgttgtaca agctgtaaca
    10141 gctacgataa agtcaccaga gtcattagca ggtgcttgaa caagttcctc agttttttct
    10201 gaagcttggt caaaaagttc gataacttgg tctgcagatg ttgcttgacg aagtttgtct
    10261 gcaaaaccgt ctttcatcaa gtattgagac aattctgcca aggctgccaa gtgagtatca
    10321 ttggcacctt ctggagctgc aatcatgaag aagaggtcag ttgcttgtcc atccaagctc
    10381 tcgtagtcaa cacccttatt tgacttagca aatagaactg tcgcttcttt gacagcagcg
    10441 tttttgctgt gaggcattgc gattccatca cccaaaccag tagaagtcaa agcttcacgc
    10501 gccaaaattc cttctttaaa tgtttcaaaa tctgttacat aaccgtgctc tgtcaaattt
    10561 ttaatcatct cgtcgatgac agctgttttt tcagttgcct gcaaatctag caacatgaca
    10621 tcttttctca ataggtcttg aattttcatc ttttttctac ctcaactttt ccatatgttt
    10681 ctttaataaa ttccgccgtt gccaagtcat ctgagaaggt agttgccgtt ccgcaagcca
    10741 ctccccattt gaaggcttct actacgtctt ttgatttgac aaattcacct gtgaatccag
    10801 caaccataga atcaccagct ccaactgaat ttttgactgt tcctttgatt ggtttagcga
    10861 agtaagctcc ctcagatgtg acaagaaggg caccatcacc agccatagag ataataacat
    10921 tttgagcacc cttagccagt aactcacgag cgtatttctc aatttcatct aaactttcga
    10981 gtttaacccc aaaaatcgct ccaagttcat gattgtttgg ttttacaaga agaggctggt
    11041 agtccaaact atcaattaag gtctgtcctt caaagtcaca gaccacttgc gcaccagtct
    11101 ggcgcgtcaa ggaaatcaaa tccttataga taacattgcc tagattttta gcacttgaac
    11161 ctgcaaagac aactgtatct tctgctgtca gactagataa aatagctttc aattcttcta
    11221 gctgaaccga ttcaacagtt ggacccgttc cgttgatttc tgtttcttgg tctgctttga
    11281 ttttaacatt gatacgagta tcttctgcca cctggacaaa acgtgtctcg atttcttcct
    11341 ctgctaaagt atctgtgata aatttaccag taaagccacc gataaatccc gtcgctgtat
    11401 ttggtatatt caaacgtttc aagacacggc tgacattgat tcctttccca ccagcaaact
    11461 tatcatcact gtccatacga tttacactac caactttgac ttggtccaaa cgaacgatat
    11521 agtcaatgga tggattgagt gtgactgtat aaatcatact tctattacct ccgttttctc
    11581 cttaataacc tgcaagagct catgcccttg actagtgata acgatagcgc gtttgagtgg
    11641 tgctaccttg gcaaagcaag tttgtccaat ttttgacgaa tccaccaaga cgtaggtctg
    11701 cttggcattc tccaaaatag ctcttttcac agctccctcc tccatatcag gagtcgtata
    11761 atagccatcg tcaacaccat tcattccgat aaaggcacgg tcaaagtgca attggttaat
    11821 ctggttaaga gcaacgcccc cgatactagc atctgtcgcc gtcttgacgt ttcctccaac
    11881 catgacagtt ggaatctgct tttcaaccaa ctgagcggca tggtgaatgg agttggtcac
    11941 aactgtaaca ttcttattga ccaattcatg aatcaaaaaa gcagttgttg ttccagcatc
    12001 gataaagatg acatcttttt ctttaatgag agaggctgct ttctgagcca gcaacttctt
    12061 ttcttgaagg tttttgacag atttttcttg aatggtttct tcttcctgta aggagtaggg
    12121 gagttctgct ccaccatgca cacgacgaag cttgttttcc gcttccaact catccaagtc
    12181 tcttcgaacc gttgattctg acgtttctag caaactaact aatttttcta gagaaactac
    12241 atgatgctga tttaactcct ctaaaattag ttgtttacgt tctgttttta acactgaatc
    12301 acctcctgtt atcgtttaca ctattcattc tatcatactt tctttcgaag tcaagcattt
    12361 tttatcattt tctttcaaaa tctatcattt ttcttatttc tagaattttt attgcaagat
    12421 aagagccttt atggtagact atttgagtaa gtattggaag attactcaag aggcttaaga
    12481 ggccgtgttg gaaacgcggt aggcgtgtaa tagcgtgcgt gggttcgaat cccatgtctt
    12541 ccgtggaaaa aagattattt ttaggatgcg acaaatgttg tatccttttt tctatccttt
    12601 ttttaaaata gggtctgttt gtgactccct ttttagcaaa agaatgcaaa ggaataccaa
    12661 agataaaaat aaaaaacgtt gatttaacaa cgttttacca aggaatgcaa aagaatgcaa
    12721 aggaataatg gagccggtgg gagtcgaacc cacgtccaaa cacctgccaa catatttgtc
    12781 tacaaccata ggttatgtat tattttaaca gcccctcgac acataactca agtctagaaa
    12841 ctgcgagtct atcaatctct tatcaagccg ctagacaagg cttaatcgta tctcgctaat
    12901 aataagacct gtcattgaac acgagcaatc caaatcgggt cacgcctgct ggtttttagg
    12961 cagctagagc gtaagaagtg ttattttttg cagttatatt taactgagcg tttacgtcgc
    13021 cacacgagtc gcaaaatatg cctcataatg cctgtcgaat ccgtaacgac cccaaaagac
    13081 aataaaacca ttatacctta tctaactcaa aaatgcaaaa agaaatcaca tacctaagat
    13141 gaagctatct gttttgaaga aattcacgaa gagaattatt ctaaaatact ttcagatgag
    13201 aattttcgta ctctctttat ttcaattcat ttgagtttaa aaactataaa atcaatcctt
    13261 atattattcg atctactttt cacttattgc acc
//
LOCUS       DAVHSI010000047        12859 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.048, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000047 DAVHSI010000000
VERSION     DAVHSI010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12859
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.048"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            138..944
                     /locus_tag="VVR21_001776"
                     /pseudo
     CDS             138..944
                     /locus_tag="VVR21_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1094..1348
                     /gene="blpM"
                     /locus_tag="VVR21_001777"
     CDS             1094..1348
                     /gene="blpM"
                     /locus_tag="VVR21_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU6055586.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            1364..1567
                     /gene="blpN"
                     /locus_tag="VVR21_001778"
     CDS             1364..1567
                     /gene="blpN"
                     /locus_tag="VVR21_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU6055587.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGL
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1811..1960
                     /gene="blpO"
                     /locus_tag="VVR21_001779"
     CDS             1811..1960
                     /gene="blpO"
                     /locus_tag="VVR21_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU6055588.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            2064..2183
                     /locus_tag="VVR21_001780"
     CDS             2064..2183
                     /locus_tag="VVR21_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU6055589.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2969..3352
                     /locus_tag="VVR21_001781"
     CDS             2969..3352
                     /locus_tag="VVR21_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU6055590.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3404..4093
                     /locus_tag="VVR21_001782"
     CDS             3404..4093
                     /locus_tag="VVR21_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6055591.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            4135..4383
                     /locus_tag="VVR21_001783"
     CDS             4135..4383
                     /locus_tag="VVR21_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055592.1"
                     /translation="MYKHLFFLDSKTLDWLTPYILVLASDTIAFNVFVLTFVSAVIFN
                     FLNPMLSLMAIFLGAGYVVGFWLLKWFVLERLELKDDV"
     gene            4413..5024
                     /locus_tag="VVR21_001784"
     CDS             4413..5024
                     /locus_tag="VVR21_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU6055593.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            5186..5980
                     /locus_tag="VVR21_001785"
     CDS             5186..5980
                     /locus_tag="VVR21_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU6055594.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5977..6612
                     /gene="trmB"
                     /locus_tag="VVR21_001786"
     CDS             5977..6612
                     /gene="trmB"
                     /locus_tag="VVR21_001786"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU6055595.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6739..7218
                     /gene="rimP"
                     /locus_tag="VVR21_001787"
     CDS             6739..7218
                     /gene="rimP"
                     /locus_tag="VVR21_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU6055596.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7262..8398
                     /gene="nusA"
                     /locus_tag="VVR21_001788"
     CDS             7262..8398
                     /gene="nusA"
                     /locus_tag="VVR21_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU6055597.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8420..8713
                     /locus_tag="VVR21_001789"
     CDS             8420..8713
                     /locus_tag="VVR21_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU6055598.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8706..9005
                     /locus_tag="VVR21_001790"
     CDS             8706..9005
                     /locus_tag="VVR21_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU6055599.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKVIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            9022..11814
                     /gene="infB"
                     /locus_tag="VVR21_001791"
     CDS             9022..11814
                     /gene="infB"
                     /locus_tag="VVR21_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU6055600.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERCKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            12065..12415
                     /gene="rbfA"
                     /locus_tag="VVR21_001792"
     CDS             12065..12415
                     /gene="rbfA"
                     /locus_tag="VVR21_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU6055601.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(12475..>12859)
                     /locus_tag="VVR21_001793"
     CDS             complement(12475..>12859)
                     /locus_tag="VVR21_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055602.1"
                     /translation="HLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLI
                     EDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNF
                     ENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         3960 a         2246 c         2879 g         3774 t
ORIGIN      
        1 ccctgcgaaa caaaatatgg tatagtatag tatattgaaa ctagaatagt acgcctctac
       61 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttatcct gttcttattt
      121 cattttacta tagttctatg aatgatgaag caagtaaaca actaactgat acacgattta
      181 aatgtcttgt tggtgttcag cacacgactt ttgaagagat gttagctgtg ttaaaaacag
      241 cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta gaagaccttc
      301 ttatggccac tcttcactat gtacgagaat accgcactta tgaagaaatt gcggctgatt
      361 ttggtatcca cgaaagcaac ttactccgtc ggagccaatg ggttgaagta actcttgttc
      421 aaaggtggtg ttacgatttc aagaactcct ctcagttctg aagacacggt aatgattgat
      481 gcgacggaag taaaaatcaa tcgccctaaa aaaaacaatt agcgaatgat tctggtaaaa
      541 agaaatttca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt
      601 tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt cgcagaaata
      661 tcggacaaac tggtaaaatc ttggctgaca gtggttatca aggacccatg aagatatatc
      721 ctcaagcaca aactccacgt aaatccagca aactcaagcc gctaacagtt gaagataaag
      781 cctataacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtaa
      841 aaacgtttaa aatgatttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa
      901 tgaatttgat tgctggcatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
      961 atgtaatttt tgcaattcaa gacgtttcga tgactattca agatctggat gaaaaatttt
     1021 aaaaaacgat gatatactaa acttgtcaaa gttacaacaa gacaaaaatt aaaaataaaa
     1081 aagagtattt gtcatggata caaaaattat ggaacaattt catgaaatgg atataactat
     1141 gttatctagt attgaaggag gcaagaataa ttggcaaact aatgtcttag aaggtggtgg
     1201 tgctgctttt ggtggctggg ggctagggac agctatttgt gctgcgagtg gtgttggagc
     1261 accatttatg ggagcatgtg gatacatagg agctaaattt ggtgtggatc tttgggcagg
     1321 agtaacaggg gcaacgggtg gattttaata aaaggagact tgtatgaata cttattgtaa
     1381 tataaatgaa acaatgctga gtgaggttta tggaggtaat tccggaggag cagctgtagt
     1441 tgctgcttta ggttgtgcag cgggtggagt gaaatatggg agacttctag gactatgggg
     1501 cgctgcaata ggaggaattg gaggagcagt ggtttgtgga tatttagcct ataccgctac
     1561 atcataaaaa tgaaagctaa attttatgaa ggctatattc tttattattc tcttcgcttt
     1621 tcaaacctat cttatttatc tatccataag tatctccgat aaaaaacaaa agactattga
     1681 attaacatca ttgaattgtt ttgtcatatt atttctaatc tatgataaat taatttttct
     1741 ctttattgcc tatgtttttt tgataatttt tatattaaac ttgttccgta actgaaaagt
     1801 gatatactat atggatacaa aaatgatgtc acaatttgca gttatggata atgaaatgct
     1861 tgcttgcgtt gaaggtggag atattgattg gggaagaaaa attagttgtg cagcaggggt
     1921 tgcatatggc gcaattgatg ggtgtgcaac aacggtttga catttctatt gggaccattt
     1981 gctataggaa taggtgtaac tggtgctgca ggtggagcta tacttggagg tgtagcctat
     2041 gcagcaatat gttggtggta attatggatt ttaaaagttt tattattggt ttagtagttg
     2101 gtatatttgg tccttatatg gatgacttaa ttagaaaaat attttcaaaa tcttccaaaa
     2161 aggatacgga tagtactctc taaaaaataa atttctcccc tgtatttgct agcttaattt
     2221 acaggggagt ttctttaata ttgtttcgcc tgtcaaaatg atatgtgata gcaggatgaa
     2281 aagtctacaa acaagttggt atcaatacaa tataaagagg aaagtatgtt tttaatgctt
     2341 actttttaaa ttttttaaca attcaagatg tttcgatgac aattcaagat ttggatgaaa
     2401 aattttaaaa aacaatgata tactaaactt gtcaaagttg caacgtgtgc tgctacatta
     2461 tgttaaaaat cgctcttgat tgataagctg gatttgttag gaaaggagta aataattatg
     2521 gataagaaaa agatagtttc gactataata tgtatagtat ttcttgtagt gtcagtagat
     2581 aattttttta gagacttaac cccgttactg ttcattttaa atattattgg cctgtcttgc
     2641 ttttcagtgc taacatacat taacataaaa gagatactct taaatataag taaatgatga
     2701 tttggttagt cctagaacca atcaacttat gtttatcggc ttggcagatt ttatgtttgt
     2761 catttgtttg tatagaggta tttcagaaac agaattctat caacaactaa tcgcttatat
     2821 aggtgtattc tctgcttgtt tatcacgctt ctgctcatgt ggggcttgaa gtattataaa
     2881 aagtagcttt ctatcctttt ctgacaggat atttgagtag aaggctctat taaattgtta
     2941 gtgaaataaa tgaatggagg tatttaatat gaaatacaga ttattttttg ttattttctt
     3001 gagtagtgtg ttggatattc ttttagggac atttttacaa atctctatcg tatctattgg
     3061 gtggcttgtt ctttacagtg gtttgtttga agcaggagtt ttccttcttg ctaataaagg
     3121 ggtggcggta aaaatcaagg aagtagatat tcgaaatcgc tttaaattta tttttggaaa
     3181 aaccttatgg tttcaaattc ttttgctcat ctttttgata atcaaacttt atcttggttt
     3241 ggatgcgagg ttgattttat tctatggaca tattttcatt gtctttaatg ccttaatgta
     3301 tctattatct agtagtcagg ttagccttaa aaagaacaaa ctgtcttctt aatcttacag
     3361 cagtagagcc tgacaaggtg aggtcatagt agggaggatt tctatgaaaa agtatcaact
     3421 tctattcaaa ataagtgcag ttttctctta cttatttttc gtatttggtc tttctcagat
     3481 gacgcttatt attcaaaatt attggcaatt ttcttcccag attggcaatt tcgtctggat
     3541 tcaaaatttc ttgagtttgc tatttagcgg agtcatgatt tggattctgg ttaagacagg
     3601 tcatggttat ctctttcaca ttccaagaaa aaaatggctt tggtattcga ttttgacagt
     3661 attagtggta gtgctccaga tctcttttaa cgttcagaca gctaaacatg ttcagtcaac
     3721 tgctgaaggt tgggctgtat tgatcggtta tagtgggacc aactttgctg agctaggtat
     3781 ctatataact ttgttctttc tgactccact tatggaagag ctaatctata gaggattact
     3841 gcaacacgcc ttttttaagc attcgagatt tggccttgat ttgcttcttc cgtcaatttt
     3901 atttgctctt cctcattttt caagcctgcc tagtttgtta gatatcttca tctttgcaac
     3961 atctggcatc atctttgcta gtttgacccg ctataccaag agcatttatc cttcctatgc
     4021 ggtgcatgtg atcaataata ttttcgcaac attaccattt ttgctgactt ttttacatag
     4081 ggtcttgggg taaaaaaaca aaaggcttgc ttttcagcca tagaggagat tatcatgtat
     4141 aaacacttat ttttcctaga ttccaaaacc ttagactggt tgacgcccta tattctagtc
     4201 ttggcttctg acaccattgc ctttaatgtt tttgtgctaa cctttgtgtc tgcggtgatc
     4261 tttaatttcc tgaatcccat gctatcttta atggctatct tcttaggggc tggctatgtg
     4321 gttggatttt ggttactaaa atggtttgtt ttggaaaggt tagagctaaa ggatgacgtg
     4381 taggaagtct gtttgttgag gaggataatt ttatggagtt ttttgataaa tttcatgcct
     4441 tgtgttttgg atttttagta ctaataattg tcattacagt tccttatacg attaaccatg
     4501 gggatttttt tcaaaatgaa tctgcattga ttcttgtaag tcttcttgta acctcgctga
     4561 gtgttgctta tgctagaaag tttgaaatga tttcttttgg gatgttaagc aagaaacaac
     4621 ttttgctttt cattgcaatc tttcttctaa gtgtacttga gacgctggtt tatattcatt
     4681 tcttcgctgt ttcttctggc tcaggggtcc aacacttggc ggaagtcagc agaggaattt
     4741 ccctgtcttt gattttgact acctcagttt ttggccccat ccaggaggaa ctcattttca
     4801 gaggacttct tcaaggtgcg gtttttgaca attcttggtt agggcttgtg ctaacttcct
     4861 ctctcttttc tttcatgcat ggaccttcta atgtcccttc gtttattttt tatctacttg
     4921 ggggcttgtt gctgggcctt gcttataaaa agagccaaaa cttatgggtt tctactctag
     4981 tccacatgtt ttacaacagt tggccactcc tatattattt ataaaaatta tgaaaaggta
     5041 agtaggagat tgtgcttacc tttttctttc tataatgata acccaaacca ctccagaggc
     5101 ttttctttga gaatcgggtt agagtggttg acgaataggc caaaaactag tagaatagta
     5161 aggaaacttt atacggagga aagaaatgga tttgggtgat aatgagctaa cactgactcc
     5221 catacctggg aaaagtggca aggcttatat gggtagctat cctgatggga agcgcatctt
     5281 tgtaaaaatg aacacctctc caatcctacc tggtctagct agagaacaaa ttgctccaca
     5341 attattatgg agtcgtcgtt tggcagatgg gcgtgatatg tgtgctcaag aatggttgac
     5401 aggcaagata ttgaccccct atgatatgaa tcgtaagcaa atcgtcaata ttttaacccg
     5461 tcttcatcgc tcacgtccgt tgatgacaca attgagtcgt ttgggctatg ccatggaaac
     5521 acctgtagat ttactacagt cttggcaaga aacggctcca gatgctttgc gtaaaaatca
     5581 ttttatcagt gaagtgatgg ctgatttacg tcagactatt ccaggattta gagaggacca
     5641 tgcgaccatt gtccatggag atgtacgaca tagtaattgg attgagacag atagtggctt
     5701 gatttattta gtagattggg attcggttcg cttgaccgat cgcatgtttg atgtggccca
     5761 tatgctctgc cattatattt cagaacatca gtggaaggaa tggttgacct actacggtta
     5821 caagtacaat caaacggtat taagtaaatt gtattggtat ggtcaattgt cttatttgag
     5881 tcagatttcc aagtattata tgaaccaaga tttagaaaat gtcaatcggg agattcatgg
     5941 tttgcgtcat ttccgagaca agtatggaaa gagaagatga gagttagaaa tcgtaaaggg
     6001 gcaacagaat tactagaggc aaatccccag tatgtggtcc tcaatccctt ggaagccaag
     6061 gcaaaatggc gggacttgtt tggcaatgat aatcccattc atgtggaagt tggaagtgga
     6121 aagggtgcct ttgtttcagg tatggccaag caaaaccctg acatcaacta tatcgggatt
     6181 gatattcaaa agtctgtttt gagctacgct ttggacaagg tgcttgaagc tggagtgtct
     6241 aacatcaagc tcttgtgggt agatggttct gacttgactg actattttga agacggtgag
     6301 attgatcgct tgtatctgaa cttttcagat ccttggccta aaaaacgcca tgaaaagcgt
     6361 cgtttgactt acaagacctt cttggatacc ttcaagcgta tcttgcctga aaatggagaa
     6421 attcatttca agacggataa ccgtggcttg tttgagtata gcctagtgag cttttctcaa
     6481 tatggcatga aactcaatgg tgtctggcta gatttgcatg ccagtgattt tgaaggcaat
     6541 gtcatgacag aatacgagca aaaattctcc aacaaggggc aagttatcta ccgagttgag
     6601 gcagaatttt aagaaatagc ctgaaatcag gctgtataag tgcttttgct ttacataagt
     6661 tagcaaatgt gctatactaa gggtaagaat atgagaaaga gaggcgggga aatatcttcg
     6721 cctcttgctt atgaggaggt ggacgcaatc gcaacaatcg tagaattagt cagagaagtt
     6781 gtagaacctg tcatagaagc tcctttcgaa ctcgtggata tcgagtatgg aaagattggc
     6841 agtgacatga ttctcagtat ttttgtagat aaacctgaag gaattacctt gaacgacacg
     6901 gcagacttga cagaaatgat cagtcctgtc ctagacacca tcaagccaga tcccttccca
     6961 gaacaatatt tcctagaaat taccagtcca ggcttggaac gtcctttgaa aaccaaggat
     7021 gccgtcgctg gagcggttgg gaaatacatc catgtcgggc tctaccaagc catcgataag
     7081 caaaaggtct ttgaaggaac cttgttggcc ttcgaagagg acgagttgac tatggaatat
     7141 atggacaaga cacgtaagaa aactgtccaa attccatata gtttagtatc aaaagcacgt
     7201 ttagcagtta aattatagaa aaagaaagga tagcttttga ggattcaaaa gtgaagaaaa
     7261 catgagtaaa gaaatgctag aggccttccg cattttggaa gaagacaagg gaatcaaaaa
     7321 agaagacatc atcgacgcag tagtagagtc gcttcgttcc gcttatcgca gacgctatgg
     7381 tcagtcagac agcgtagcta ttgacttcaa cgaaaaaaca ggtgacttta cagtttatac
     7441 tgtccgtgaa gttgttgatg aagtatttga tagccgtttg gaaatcagct tgaaagatgc
     7501 tcttgccatt aattcagctt atgaacttgg agacaaaatc aagtttgaag aagcaccagc
     7561 tgagtttggt cgtgtagcag cccaatctgc caaacaaacc atcatggaaa aaatgcgcaa
     7621 gcaaacacgt gccatcactt acaatactta caaagaacat gagcaagaaa tcatgtctgg
     7681 tacagtagaa cgctttgaca accgctttat ctatgtcaac cttggtagca tcgaagccca
     7741 attgtcaaaa caagaccaaa ttcctggaga agtttttgct tctcatgatc gtatcgaagt
     7801 ttatgtttac aaggttgaag acaaccctcg tggtgtgaac gtctttgtta gccgtagcca
     7861 tccagaaatg atcaaacgtt tgatggagca agaaattcca gaagtttatg atggaactgt
     7921 tgaaatcatg agcgtggctc gtgaagcagg tgaccgtacg aaggttgctg ttcgtagcca
     7981 caatccaaac gtagatgcta tcggtacaat cgttggacgt ggtggtgcta atatcaagaa
     8041 gattactagc aaattccacc cagctcgtta cgatgctaaa aatgaccgca tggtaccaat
     8101 cgaagaaaat atcgatgtta tcgagtgggt agcagatcca gctgaattta tctacaatgc
     8161 catcgctcct gctgaggttg accaagttat ctttgatgaa aacgacagca aacgtgcctt
     8221 ggtggttgtt ccagataaca agctttctct tgccattggt cgtcgtggac aaaacgtgcg
     8281 cttggcggct cacttgactg gttatcgtat cgatatcaag tctgctagcg aatttgaagc
     8341 catggaagac gctgcttcag tagagttgga agtagaaaac gatactgtag aagaataaaa
     8401 gctgctagag gagggaaaga tgaaaacaag aaaaatccct ttgcgcaagt ctgttgtgtc
     8461 taacgaagtg attgataagc gtgatttgct ccgcattgtc aagaacaagg aaggacaagt
     8521 ctttattgat cctacgggca aggccaatgg ccgcggcgct tatatcaaac tagacaatgc
     8581 agaagcccta gaggcgaaaa agaagaaggt ctttaaccgc agctttagca tggaagtgga
     8641 agaaagcttt tatgacgagt tgatcgctta tgtggatcac aaagtgaaaa gaagagagtt
     8701 gggacttgaa taagcaaaag ataagtaatc tcttggggct tgctcagcga gcagggcgca
     8761 tcatatcggg tgaagaattg gtggtcaagg tcattcaaga cggcaaggcc aagttggtct
     8821 ttctagctca tgatgctgga cccaatctga ccaagaagat tcaagataaa agtcattatt
     8881 atcaagtaga aattgtaacc gtgttttcaa cactggaatt aagcatagca gtcgggaaat
     8941 cgagaaaggt tttggctgta acagatgctg gatttacaaa gaaaatgagg tctcttatgg
     9001 aatagaagag gaggacatga tttgtctaag aaaagattgt acgaaatcgc aaaagaactt
     9061 ggaaaagaaa gtaaagaagt tgtagcgcgt gcaaaagagt tgggcttgga tgtgaaaagc
     9121 cactcatcaa gtgtggaaga agctgtcgct gcaaaaattg ctgccagctt taagcctgca
     9181 gctgctccga aagtagaagc aaaacctgca gcaccaaaag taagtgcaga aaagaaagcc
     9241 gaaaaatctg agccagctaa accagctgta gctaaggaag aggcaaaacc ggctgagcca
     9301 gttgctccga aaacagaaaa agtagcagcg aaaccgcaaa gtcgtaattt caaggctgag
     9361 cgtgaagccc gtgctaaaga gcaggcagaa cgatgcaagc aaaataaggg caataaccgt
     9421 gaccaacaac aaaacggaaa ccgtcagaaa aacgacggcc gtaatggtgg aaaacaaggt
     9481 caaagcaacc gcgacaatcg tcgctttaat gaccaagcta agaagcagca aggtcagcaa
     9541 aaacgtagaa atgagcgccg tcagcaagag gataaacgtt caaatcaagc ggctccacgt
     9601 attgacttta aagcccgtgc agcagcccta aaagcagagc aaaatgcaga gtacgctcgt
     9661 tcaagtgagg aacgcttcaa gcagtatcag gctgctaaag aagccttggc tcaagctaac
     9721 aaacgcaagg aaccagagga aatctttgaa gaagcggcta agttagctga acaagcacag
     9781 caagttcaag cagtggttga agtcgtccct gagaaaaaag aacctgcagt ggatacacgt
     9841 cgtaaaaaac aagctcgacc agacaaaaat cgtgacgatt atgatcatga agaagatggt
     9901 cctagaaaac aacaaaagaa tcgaagtagt caaaatcaag tgagaaatca aaagaatagt
     9961 aactggaata acaacaaaaa gaacaaaaaa ggcaataaca agaacaaccg taatcagact
    10021 ccaaaacctg ttacggagcg taaattccat gaattgccaa cagaatttga atatacagat
    10081 ggtatgaccg ttgcggaaat cgcaaaacgt atcaaacgtg aaccagctga aatcgttaag
    10141 aaacttttca tgatgggtgt catggccaca caaaaccaat ccttggatgg ggaaacaatt
    10201 gaactcctca tggtggatta cggtatcgaa gccaaacaaa aggttgaagt ggataatgct
    10261 gacatcgaac gtttctttgt cgaagatggt tatctcaatg aagatgaatt ggttgagcgt
    10321 ccaccagttg ttactatcat gggacacgtt gaccacggta aaacaaccct tttggatact
    10381 cttcgtaact cacgtgttgc gacaggtgaa gcaggtggta ttactcagca tatcggtgcc
    10441 taccaaatcg tggaaaatgg taagaagatt accttccttg atacaccagg acacgcggcc
    10501 tttacatcaa tgcgtgcgcg tggtgcttct gttaccgata ttacgatctt ggtcgtagcg
    10561 gcagatgacg gggttatgcc tcagactatt gaagccatca accactcaaa agcagctaac
    10621 gttccaatca tcgtagctat taacaagatt gataaaccag gtgctaaccc agaacgcgtt
    10681 atcggtgaat tggcagagca tggtgtgatg tcaaccgctt ggggtggaga ttctgaattt
    10741 gttgaaatct cggctaaatt caaccaaaat atcgaagaat tgttggaaac agtccttctt
    10801 gtggctgaaa tccaagaact caaagcagac ccaacagtgc gtgcaatcgg tacggttatc
    10861 gaagcgcgct tggataaagg aaaaggtgcg gtcgcaaccc ttcttgttca acaaggtacc
    10921 ttgaatgttc aagacccaat cgttgtcgga aataccttcg gtcgtgtccg tgctatgacc
    10981 aacgaccttg gtcgtcgtgt taaagttgct ggaccatcaa caccagtctc tatcacaggt
    11041 ttgaacgaag caccgatggc gggtgaccac tttgccgttt acgaggatga aaaatctgcg
    11101 cgtgcagcag gtgaagagcg tgccaaacgt gccctcatga aacaacgtca agctacccaa
    11161 cgtgttagcc ttgaaaacct ctttgatacc cttaaagctg gggaactcaa atctgttaat
    11221 gttatcatca aggccgatgt acaaggttct gttgaagccc tttctgcctc acttcaaaag
    11281 attgacgtgg aaggtgtcaa agtgactatc gtccactcag cggtcggtgc tatcaacgaa
    11341 tcagacgtga cccttgccga agcttcaaat gcctttatcg ttggtttcaa cgtacgccct
    11401 acaccacaag ctcgtcaaca agcagaagct gacgatgtgg aaatccgtct tcacagcatt
    11461 atctacaagg ttatcgaaga gatggaagaa gctatgaaag ggatgcttga tccagaattt
    11521 gaagaaaaag ttattggtga agcggttatc cgtgaaacct tcaaggtgtc taaagtggga
    11581 actatcggtg gatttatggt tatcaacggt aaggttgccc gtgactctaa agtccgtgtt
    11641 atccgtgatg gtgtcgttat ctatgatggt gaactcgcaa gcttgaaaca ctataaagac
    11701 gacgttaagg aagttacaaa cggccgtgaa ggtggattga tgatcgacgg ctacaatgat
    11761 attaagatgg atgatgtgat tgaggcgtat gtcatggaag aaatcaagag ataagatttt
    11821 ttgctccttt cttaggtggt gagggacgca agcaaaccga tggtttcatt gcttattttt
    11881 gagcctaggg tctcaaaaat cccctgtgat gggactgata aatcagttcc atcactttca
    11941 ccacggcgaa agaagcagat gacttcaaat tgaacttcgt ttcaatttaa actgaaaatc
    12001 aagaagttta aaatagctag gtctgctggc ctagcttttg gttcaaagta gagaaaggaa
    12061 tatcatggca aatcatttcc gtacagatcg tgtgggcatg gaaatcaagc gtgaagtcaa
    12121 tgagattttg caaaagaaag tccgtgatcc acgtgtccaa ggtgtgacca tcacagatgt
    12181 tcagatgctg ggtgacttgt ctgttgccaa ggtttattac accattttga gtaaccttgc
    12241 ttcggataac caaaaagccc aaatcgggct tgaaaaagca actggtacca tcaaacgtga
    12301 acttggtcgc aatttgaaat tgtacaaaat cccagatttg accttcgtca aagacgagtc
    12361 catcgagtat ggaaacaaga ttgacgagat gctacgcaat ctggataaga actaaagaag
    12421 aggggttgcc cctctttttc ggctctttgt caactgtagt gggttgaaga aaagctaagc
    12481 tcgagaaagg acaaatttcg tcctttcttt tttgatattc agggcgataa aaatccgttt
    12541 tttgaagttt tcaaagttcc gaaaaccaaa ggcattgcgc ttgataagtt tgatgagatt
    12601 attggtcgct tccaatttgg cgtttgaata gggtagttga agggcgttga cgattttctc
    12661 tttgttcttt agaaaggttt taaagacagt ctgaaaaata ggatgaacct gcttcagatt
    12721 gtcctcaatg agtccgaaaa atttctcagg gtctttgttc tgaaagtgaa aaagtaagag
    12781 ttgatagatc tgatagtggt gtttcaagtc ttctgaatag cttaaaatct tgtcaagaat
    12841 ttctttattt gttaagtgc
//
LOCUS       DAVHSI010000048        12274 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.049, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000048 DAVHSI010000000
VERSION     DAVHSI010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.049"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            145..417
                     /gene="rpsP"
                     /locus_tag="VVR21_001794"
     CDS             145..417
                     /gene="rpsP"
                     /locus_tag="VVR21_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU6055603.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            437..676
                     /locus_tag="VVR21_001795"
     CDS             437..676
                     /locus_tag="VVR21_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU6055604.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            1253..2041
                     /locus_tag="VVR21_001796"
     CDS             1253..2041
                     /locus_tag="VVR21_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6055605.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            2072..2590
                     /gene="rimM"
                     /locus_tag="VVR21_001797"
     CDS             2072..2590
                     /gene="rimM"
                     /locus_tag="VVR21_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU6055606.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            2580..3299
                     /gene="trmD"
                     /locus_tag="VVR21_001798"
     CDS             2580..3299
                     /gene="trmD"
                     /locus_tag="VVR21_001798"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU6055607.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            3311..3649
                     /locus_tag="VVR21_001799"
     CDS             3311..3649
                     /locus_tag="VVR21_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055608.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(3680..4000)
                     /locus_tag="VVR21_001800"
     CDS             complement(3680..4000)
                     /locus_tag="VVR21_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055609.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            4098..4313
                     /locus_tag="VVR21_001801"
     CDS             4098..4313
                     /locus_tag="VVR21_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU6055610.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(4382..4462)
                     /locus_tag="VVR21_001802"
                     /pseudo
     CDS             complement(4382..4462)
                     /locus_tag="VVR21_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4518..5054)
                     /locus_tag="VVR21_001803"
     CDS             complement(4518..5054)
                     /locus_tag="VVR21_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU6055611.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(5251..6597)
                     /gene="gor"
                     /locus_tag="VVR21_001804"
     CDS             complement(5251..6597)
                     /gene="gor"
                     /locus_tag="VVR21_001804"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU6055612.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAQAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGVTKADFDATVAIHPTSSEEFVTMR"
     gene            6862..8061
                     /locus_tag="VVR21_001805"
     CDS             6862..8061
                     /locus_tag="VVR21_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU6055613.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     LTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            8045..8746
                     /locus_tag="VVR21_001806"
     CDS             8045..8746
                     /locus_tag="VVR21_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055614.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            8748..10007
                     /locus_tag="VVR21_001807"
     CDS             8748..10007
                     /locus_tag="VVR21_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055615.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            10131..12128
                     /gene="metG"
                     /locus_tag="VVR21_001808"
     CDS             10131..12128
                     /gene="metG"
                     /locus_tag="VVR21_001808"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU6055616.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDAVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT         3846 a         2230 c         2683 g         3515 t
ORIGIN      
        1 aacaaatttc taaatacttt aagaaattta tagtctgtca agtttttttc ttgacacatg
       61 ccagaaatct gctataatag aacatgtgct aaatagctca gctatttcac caaaataaaa
      121 aattaaagaa atgagacttt aaaaatggca gttaaaatcc gtttgactcg tatgggttct
      181 aagaaaaaac ctttctaccg tatcaacgta gcagattcac gttcaccacg tgacggacgt
      241 ttcatcgaaa cagttggaac ttacaaccca cttgttgctg aaaaccaagt aactttgaaa
      301 gaagaccgcg ttcttgcatg gttggctaat ggagctcaac cttcagacac agtacgtaac
      361 atcctttcaa aagaaggcgt attgaaaaaa ttccacgatt ctaaattttc aaaataagtt
      421 taaagtaggt tgacagatgg atacgattga aaatctcatt attgcgattg tgaaaccctt
      481 aatttcacaa ccagatgcct taactatcaa gattgaggat acaccagaat ttttggaata
      541 tcatttgaat cttgatcaaa gcgatgtggg tcgtgtaatc ggtcgtaagg gtcgcactat
      601 ttctgcgata agaacgattg tctactctgt cccaactgaa tacaaaaaag taagaatcgt
      661 tattgacgaa aaataagaag ggcgggacgg atgtctcgct tttttgtgtg gaatagaaga
      721 tatagtaaaa tgaaacaaga acaggacaaa tcgatcagga cagtcaaatc gatttctaac
      781 aatgttttag aagtaaaggt gtactattct agtttcaata tactataaaa gattgaacgt
      841 ttaggcaatt ccaagactac ttaatcgaac attaacagca gtctcggact gatgaaggtc
      901 tctttatgaa gttagtggag gaagtcggag aagtagccga ggttttgaat aggcgctctg
      961 gtcgaaaaga agggatagga ttcgaacgag ggacttgcca gagaactggc tgatatcatt
     1021 tactacaccg tcgcaatcgt agctattaat catattgacc ttaccaagac tgtctttgag
     1081 aaagacaaaa ccgcagccgt taattaccaa cataaacata atttggaagg attattgaag
     1141 ggaaagtaga gatattgtcc ccttcctcca acttgagaaa atccttggaa cgtgataaaa
     1201 taaaggataa ggatttttaa taattcatta tatagaatca gtggatttct ttatgaagag
     1261 gtttgaagta tctacagaaa ttggtagtct ctctgttgct tatcaaaagc aaaagaaagt
     1321 gctagtttgt ctaaacggag caggtttgct accaagttat gaaaattttt cacttatact
     1381 tgaaaaacct cctcctacaa ttggttattt gacaattgat tttccgaaca caggtaggag
     1441 tccgattcat gaccaagctg gaaaaaatct agataatctt gcagatgtgg tttatgaagc
     1501 acttgaagaa ttagggattt ctgaatatat actttgtgta catagttgga gtggaatttt
     1561 agcttgcaaa ttactcgaga aaccaattaa gtgtcagact ttagtagcaa ttgaaccgac
     1621 aactaaaaaa gtcatgtttg ctgatttttc agaaaatcct tatccagaaa tggaagagca
     1681 gatgaggctg attgacgagt gtggtcctga actttatttt aagaacttaa ctcaagcaac
     1741 atttagtcct gaaacgaata aaaaaatctg ggaattaatg caagaaaaag gcttagagtt
     1801 ggaaaatcaa gatccagaat ttcagatatc tggagagatt actgaggaag attttgagaa
     1861 tttgtcgata gaatctcatg tccctgtatt tattttttgt cagacttata gagaaaaaga
     1921 gtacagagaa tcagaatatt ggacttccaa tactaaactc attttaggag ggaatcacca
     1981 ttatttacaa tggtcagaat cggaaaaaat tgcggctatt attcgagaat tgtcagaata
     2041 agatggaaaa aaggagatta caggagacaa gatgaactac tttaatgttg ggaaaatcgt
     2101 taatacgcag ggattacagg gtgagatgcg agtcttgtct gtgacggatt ttgcagaaga
     2161 acggtttaaa aaaggagctg agctggcttt gtttgatgaa aaagatcagt ttgtccaaac
     2221 agtgaccatc gctagccacc gtaaacagaa gaactttgac attattaaat tcaaagatat
     2281 gtaccatatc aatactatcg aaaagtacaa gggatacagt ctcaaggtcg ctgaggaaga
     2341 tttgaatgac ctagacgatg gtgaatttta ctatcacgag attatcggtt tggaagtcta
     2401 tgagggtgat agcttggttg gaaccatcaa ggaaatcctg caaccaggtg ctaatgatgt
     2461 ctgggtggtc aaacgaaaag gcaaacgtga tttgctttta ccttatatcc caccagtggt
     2521 tctcaatgtt gatattccaa ataaacgggt cgatgtggaa atcttagaag ggttagacga
     2581 tgaagattga tattttaacc ctctttccag agatgttttc tccactggag cactcaatcg
     2641 ttggaaaggc tcgagaaaaa gggctcttgg atatccagta tcataatttt cgagaaaatg
     2701 ctgaaaaggc ccgtcatgta gatgatgagc cctacggagg cggtcagggc atgttgctca
     2761 gagcacaacc tattttcgat tcctttgatg ctattgaaaa gaaaaatccg cgcgttattc
     2821 tccttgatcc tgctggaaag cagtttgatc aggcttatgc tgaagatttg gctcaagagg
     2881 aagagctaat ctttatctgt gggcactatg agggttatga tgagcgcatt aagaccttgg
     2941 taacagatga gatttcccta ggcgactatg tcctcactgg tggagaattg gcagctatga
     3001 ccatgattga tgctacagtt cgcctgattc cagaagtgat tggcaaggag tctagccacc
     3061 aagatgatag tttttcttca ggtcttttag aatatcctca gtacacacgt ccctatgatt
     3121 atcgaggcat ggtcgtgcca gatgtattga tgagtggcca ccatgaaaag attcgtcagt
     3181 ggcgattgta cgagagttta aagaaaacct acgagcgcag accggattta cttgaacatt
     3241 atcaactgac agtagaagaa gaaaaaatgc tggcagaaat caaagaaaac aaagaataaa
     3301 ggagaaacct atgcaagtaa tcaaacgtaa tggcgaaatt gctgaattta atccagataa
     3361 gatttaccaa gccatcttga aggcagccca aactgtttat gttttgacag atgatttgcg
     3421 tcaaaatctt gctcaagtca ctaagaaggt agttttggat ttacaagaag ccaaggtgga
     3481 acgtgcgact atcagtatga ttcaatctat ggttgaacat cgtttattgg gcgcaggtta
     3541 cattaccatt gcagaacact acatttccta tcgtttacaa cgtgacttgg aaagaagtgg
     3601 ttatggagat catatcgcag ttcatttaca ttttgaacaa attcgctaag aaaaaagagt
     3661 gggatgaagc aactacatct cactctttct taaatctatt tttttgggct gtttggacag
     3721 ttgaggggac aaatcgcagg cgttgaatat cgcttatacg gataatccgg ctcacatttt
     3781 tggcaaaatt tttcacgata atttgctggc cttgctgatc atatttgatg atatcacctg
     3841 taaagcttgt ctcagacaag ataaggtgaa cagcggtttg tttctggata gcctcttcaa
     3901 tagtggctgt aagggagttg gtttcagtct ggtcaggttg gtcatgtcca tttaaaaaat
     3961 catgtatttt atctagaact tgctggaatt tatgtctcat attggcctcc cttcttttat
     4021 atcaatatta tataaaattt tcctaaaatc tacaagattt tacgaataaa ctaatgaaac
     4081 taaaaaagga gaagaaaatg gcagaattta catttgaaat cgaagagcac ttgttgactc
     4141 tttctgaaaa cgaaaaaggt tggaccaagg aaattaaccg tgtgagcttt aatggtgccc
     4201 ctgcaaagtt tgatattcgt gcttggagtc cagaccatac taaaatgggc aaagggatta
     4261 ctctctcaaa tgaagaattt caaacgatgg tggatgcctt taaaggcaac taatactctt
     4321 cgaaaatctc ttcaaaccgc atcagctttg ccttgccgta tgtatggtta ctgacttcgt
     4381 cagtttcatc cacaacctca aaacagtgtt ttgagcagcc tgcggctagc ttcctagttt
     4441 gctctttgat tttcattgag tataagtttt caaaataaaa aaaaggatat tgagtcatga
     4501 taactcggta tcctttttta gttagtaaag taagcctgat ttttaaggcg ttgaagtagg
     4561 ggacggctaa taaaactaat agccagaagt ttgccaaggt ctggaatgat aaagggaaga
     4621 acccccacaa caagagcttt ttcaaatgcc attccagcta ggaaatgcaa gctgagaatc
     4681 ccgccgacaa agacaagggc atcacccaag aggtttgcaa gaaaaatctt aacaacacca
     4741 ctcttgctgt tagttagaga ggaagtaagt ccagagtaaa cgagataaaa ccaaagatag
     4801 cctgcagtag ggccaactaa agcctgaaaa ccagctccac ctcctgcaaa gacaggaaga
     4861 ccgatagcac ctagaagaag atagagtcca gcagaaagta cagcctctct cggtctaaag
     4921 acagtagcaa tcaagccgat tgcaaagttt tgcagagtga agggaacagg tccaattgga
     4981 agactgattt gtgccaaaac agcaatgaga gcagccccaa tagcagggat agcataaacg
     5041 tgagcttttt tcaaaatagt taacctcttt tctaatgtat agtaactatt atactcatat
     5101 aggagtcgat gtcaaccatt ttttaaaaac aaggtaacaa aaactgtaac agccgatttt
     5161 cgtgactagt caagttggat aatttttttg ttgattcgaa aatcattaaa aaagaagcag
     5221 acatatttat atcagcttct tttgtttcga ttaacgcatg gttacaaatt cttcagatga
     5281 agttgggtga atcgctacag ttgcgtcaaa gtcagccttg gttactccca ttttgatagc
     5341 aacggcaaat ccctgaatca tttcatcaac gccgtagcca attccatgaa gtccgacaac
     5401 tttttcttct gaaccagctg ttatgagttt gaaacgggat tcttgacggt tgcgagtgca
     5461 agcagagtac atagatgcaa agcttgattt gtaaaccttg atttggtctt gaccgtattc
     5521 tttaatagct tgctcttctg tcaaaccaac agttccgata gcagggtgtg aaaagacaac
     5581 agttggaata gttgagtaat ccatttttgc agtagttttt ccgttaaaga gacgttcaga
     5641 tagggtacgt ccggccttga ttgcaactgg agtcagttct ttctcgcccg ttacatcacc
     5701 tagagcatag attccctcaa caacagtatt ttggtattca tccacttgga taaagccacg
     5761 ttcgttcaga gtcactccag ctttttcaag ttgcaagccc ttaacgtttg gacggcggcc
     5821 tgtagcccag ataacttggc tagctgtgtg actagtacca tcttcgaaat gaatggtaat
     5881 gccgtcagta gttttttcta acttgacagg gactttgtga gtgtgaagtg gtaagtttgt
     5941 tctttccatt tccttgacca aaccttcaac gatgtaggaa tcaaaaccac gtaaaggacg
     6001 atcgcggcga acaaagagat ctgtcttgac accaaaagtg tggagtacgc cagctaattc
     6061 aacggcgata taaccagcgc ctagaatggc aactgactct ggaagttctt cccaggcaaa
     6121 tacatcatca gaagagccac ctagctcagc accaggaata ttaggaatac ttggatgggc
     6181 acctgtagca atcacgatat gtttagcacg aatcagttca ccatttacgc ttacagtatg
     6241 agaatctaca aattcagcat gaccttcaat caagtctaca ccgttgcgtt taaaactgcc
     6301 atcataagaa gaacgagcgc gatcaatgta ggattcacga ttgcgacgta gggttgcaaa
     6361 gtcaaagtta agatcagtag tcttaaagcc gtagtcttct ccaaattgat ggaaagtctc
     6421 agcgatttgt gccccgtacc acatgatttt tttaggaaca caaccgacgt tgacacaggt
     6481 tccacctaat ttcttttcct caataacggc tgcttgggct ccatgttcac cagcacggtt
     6541 catggtagcg attcctccgc tacctccacc gatagcaatg atatcatatt ctctcattga
     6601 aaactccttt gtaatctttt aaatagtaga gcgtcttttt tgatagttat attttattct
     6661 ttttttgatt tgattgcaaa aatctgctac gcacaaaaaa ttgcaaaaaa gcttgccaaa
     6721 taagtcaaga tagtgtatta tatatctagt acaatagaaa agcaaaattc cgaacgattg
     6781 tttaatcctg aactgtattg tttgctggag ggaaatttgg tataatagca aagtattgta
     6841 aaaaagaaaa ggagtttcat tatgaagaaa aagaatggta aagctaaaaa gtggcaactg
     6901 tatgcagcaa tcggtgctgc gagtgtagtt gtattgggtg ctggggggat tttactcttt
     6961 agacaacctt ctcagactgc tctaaaagat gagcttactc atcttgttgt tgccaaggaa
     7021 ggaagcgtgg cctcctctgt tttattgtca gggacagtaa cagcaaaaaa tgaacaatat
     7081 gtttattttg atgctagtaa gggtgattta gatgaaatcc ttgtttctgt gggcgataag
     7141 gtcagcgaag ggcaggcttt agtcaagtac agtagttcag aagcgcaggc ggcctatgat
     7201 tcagctagtc gagcagtagc tagggcagat cgtcatatca atgaactcaa tcaagcacga
     7261 aatgaagccg cttcagctcc ggctccacag ttaccagcgc cagtaggagg agaagatgca
     7321 acggtgcaaa gcccaactcc agtggctgga aattctgttg cttctattga cgctcaattg
     7381 ggtgatgccc gtgatgcgcg tgcagatgct gcggcgcaat taagcaaggc tcaaagtcaa
     7441 ttggatgcaa caactgttct cagtacccta gagggaactg tggtcgaagt caatagcaat
     7501 gtttctaaat ctccaacagg ggcgagtcaa gttatggttc atattgtcag caatgaaaat
     7561 ttacaagtca agggagaatt gtctgagtac aatctagcca acctttctgt aggtcaagaa
     7621 gtaagcttta cttctaaagt gtatcctgat aaaaaatgga ctgggaaatt aagctatatt
     7681 tctgactatc ctaaaaacaa tggtgaagca gctagtccag cagccgggaa taatacaggt
     7741 tctaaatacc cttatactat tgatgtgaca ggcgaggttg gtgatttgaa acaaggtttt
     7801 tctgtcaaca ttgaggttaa aagcaaaact aaggctattc ttgttcctgt tagcagtcta
     7861 gtaatggatg atagtaaaaa ttatgtctgg attgtggatg aacaacaaaa ggctaaaaaa
     7921 gttgaggttt cattgggaaa tgctgacgca gaaaatcaag aaatcacttc tggtttgaca
     7981 aatggtgcta aggtcatcag taatccaaca tcttccttgg aagaaggaaa agaggtgaag
     8041 gctgatgaag caactaatta gtctaaaaaa tatcttcaga agctaccgta atggtgacca
     8101 agaactgcag gttctcaaaa atatcaatct agaagtgaat gagggtgaat ttgtagccat
     8161 catgggacca tctgggtctg gtaagtccac tctgatgaat acgattggca tgttggatac
     8221 accaaccagt ggagaatatt atcttgaagg tcaagaagtg gctgggcttg gtgaaaaaca
     8281 actggctaag gtccgtaacc aacaaatcgg ttttgtcttt cagcagttct ttcttctatc
     8341 gaagctcaat gctctgcaaa atgtagaatt gcccttgatt tacgcaggag tttcgtcttc
     8401 aaaacgtcgt aagttggctg aggaatattt agacaaggtt gaattgacag aacgtagtca
     8461 ccatttacct tcagaattat ctggtggtca aaagcaacgt gtagccattg cgcgtgcctt
     8521 ggtaaacaat ccttctatta tcctagcgga tgaaccgaca ggagccttag ataccaaaac
     8581 aggtaaccaa attatgcaat tattggttga tttgaataaa gaaggaaaaa ccattatcat
     8641 ggtaacgcat gagcctgaga ttgctgccta tgccaaacgt cagattgtca ttcgggatgg
     8701 ggtcatttcg tctgacagtg ctcagttagg aaaggaggaa aactaagatg cagaatctga
     8761 aatttgcctt ttcatctatc atggctcaca agatgcgttc tttgcttact atgattggga
     8821 ttattatcgg tgtttcatca gttgttgtga ttatggcttt gggtgattcc ctatctcgtc
     8881 aagtcaataa agatatgact aaatctcaga aaaatattag cgtctttttc tctcctaaaa
     8941 aaagtaaaga tgggtctttt actcagaaac aatcagcttt tacggtttct ggaaaggaag
     9001 aggaagttcc tgttgaaccg ccaaaaccgc aagaatcctg ggttcaagag gcagctaaac
     9061 tgaagggagt ggatagttac tatgtaacca attcaacgaa tgccatcttg acctatcaag
     9121 ataaaaaggt tgagaatgct aatttgacag gtggaaacag aacttacatg gacgctgtta
     9181 agaatgaaat tattgcaggt cgtagtctga gagagcaaga tttcaaagag tttgcaagtg
     9241 ttattttgct agatgaggaa ttgtccatta gtttatttga atctcctcaa gaggctatta
     9301 acaaggttgt agaagtcaat ggatttagtt accgggtcat tggggtttat actagtccgg
     9361 aggctaaaag gtcaaaaata tatgggtttg gtggcttgcc tattactacc aatatctccc
     9421 ttgctgcgaa ttttaatata gatgaaatag ctagtattgt ctttcgagtg aatgatacca
     9481 gtttaacccc aactctgggt ccagaactgg cacgaaaaat gacagagctt gcaggcttac
     9541 aacagggaga ataccaggtg gcagatgagt ccgttgtatt tgcagaaatt caacaatcgt
     9601 ttagttttat gacgacgatt attagttcca tcgcagggat ttctctcttt gttggaggaa
     9661 ctggtgtcat gaacatcatg ctggtttcgg tgacagagcg cactcgtgag attggtcttc
     9721 gtaaggcttt gggtgcaaca cgtgccaata ttttaattca gtttttgatt gaatccatga
     9781 ttttgacctt gttaggtggc ttaattggct tgacaattgc aagtggttta actgccttag
     9841 caggtttgtt actgcaaggt ttaatagaag gtatagaagt tggagtatca atcccagttg
     9901 ccctatttag tcttgcagtt tcggctagtg ttggtatgat ttttggagtc ttgccagcca
     9961 acaaggcatc gaaacttgat ccaattgaag cccttcgtta tgaatgagat caacaagatg
    10021 gacactcgtc tatcttgttt ttgtatggat ttccctatcg aaattcatta aaaatgtgat
    10081 ataatgaagt gttagaaaaa caggtttcat ttgcctggaa aggaaaaatt atgtctgaaa
    10141 aaaattttta tattacaacg ccgatttact atccatctgg gaaacttcat atcggttctg
    10201 cctacacaac tatcgcatgt gatgtcctag cacgttacaa acgcctgatg ggctacgatg
    10261 tattttatct gacaggtctt gatgaacatg gtcagaaaat ccagcagaaa gcggaagaag
    10321 ctggtattac acctcaagcc tatgttgatg gaatggcggt tggagttaaa gaactctggc
    10381 aattactaga tatctcatac gataaattta tccgtacaac cgatgactac catgaaaaag
    10441 ttgtcgcaca ggtctttgaa cgcttacttg ctcaagatga tatctacttg ggtgaatact
    10501 ctggttggta ttcagtatca gacgaagaat tctttacaga aagccagctg gcagaagttt
    10561 tccgtgatga agctggaaat gtgactggtg gtattgctcc atcaggtcat gaggttgaat
    10621 gggtttctga agaatcatac ttccttcgcc ttagcaaata ccaagaccgt ttggtcgaat
    10681 ttttcaaagc tcatcctgaa tttatcacgc cagatggtcg ccttaatgaa atgctacgca
    10741 acttcatcga gccaggcttg gaagatttgg cggtatctcg tacaaccttt acatggggag
    10801 tgcctgtccc atcaaatcca aaacacgttg tctacgtttg gattgatgcc cttcttaact
    10861 atgcgacagc tcttggctac gctcaagacg aacatggtaa ctttgacaag ttctggaatg
    10921 gaacagtctt ccatatggta ggaaaagata tccttcgctt ccactctatc tactggccaa
    10981 tccttcttat gatgttggat gttaaattac ctgatcgttt gattgcccat ggttggtttg
    11041 tcatgaaaga cggaaaaatg tctaagtcaa aagggaatgt cgtttaccct gaaatgttgg
    11101 tagagcgtta tggactagat ccacttcgtt actacctcat gcgtaacctt ccagttggtt
    11161 cagacggaac ctttactcct gaagactatg tcggccgtat caactatgaa ttggctaatg
    11221 accttgggaa cctccttaac cgtacggttt ccatgattaa taagtacttt gatggacaaa
    11281 tccctgccta tgtagaaggt gtgactgaat ttgatcatgt tcttgctgag gttgcagaac
    11341 aatcaatcgc agacttccat acacacatgg aagcagttga ctatccacgt gcgcttgaag
    11401 cagtctggac tctgatctct cgtaccaata aatacatcga tgagaccgca ccatgggtct
    11461 tggccaagga tgaagctctt cgtgaccaat tggcaagtgt catgagccac ttggcagcca
    11521 gcattcgtgt agttgctcac ttgattgaac catttatgat ggaaactagt cgtgcagttt
    11581 tgactcaact tggtttggaa gaagtttcta gtcttgaaaa cttgagtttg gctgacttcc
    11641 cagcagatgt gactgtagtt gccaaaggaa cacctatctt tccacgtcta aatatggaag
    11701 aagaaatcgc ctatatcaag gaacaaatgg aaggcaataa accagcagtc gaaaaagaat
    11761 ggaatccgga cgcagttgag ctcaaactaa acaaggatga aatcaagttt gaagactttg
    11821 acaaggttga aatccgtgtc gcagaagtca aagaagtgtc taaagtagaa ggttcagata
    11881 agttgcttca attccgcttg gatgctggtg atggagaaga tcgtcagatt ctttcaggaa
    11941 ttgcaaaata ctatccaaat gaacaagaat tggtcggcaa gaaagttcaa atcgttgcta
    12001 acctcaaacc acgtaaaatg atgaaaaaat atgtcagcca gggtatgatt ctctcagctg
    12061 aacatgatgg caaattaacc cttctcacag ttgatccagc tgtaccaaat ggaagtgtga
    12121 ttgggtaaaa gtagacagga ctagttcaga ctagttctgt ttttttattt atactcaatg
    12181 aaaatcaaag agcaaactag gaagctagcc gcaggttgct caaaacactg ttttgaggtt
    12241 gtagatagaa ctgacgaagt cagctcaaaa catg
//
LOCUS       DAVHSI010000049        12210 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.050, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000049 DAVHSI010000000
VERSION     DAVHSI010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.050"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            1..574
                     /locus_tag="VVR21_001809"
                     /pseudo
     CDS             1..574
                     /locus_tag="VVR21_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(690..1493)
                     /locus_tag="VVR21_001810"
     CDS             complement(690..1493)
                     /locus_tag="VVR21_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU6055617.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1770..2525)
                     /locus_tag="VVR21_001811"
     CDS             complement(1770..2525)
                     /locus_tag="VVR21_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU6055618.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2595..5246)
                     /locus_tag="VVR21_001812"
     CDS             complement(2595..5246)
                     /locus_tag="VVR21_001812"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU6055619.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQGEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGCKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5239..5817)
                     /locus_tag="VVR21_001813"
     CDS             complement(5239..5817)
                     /locus_tag="VVR21_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU6055620.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5817..6377)
                     /locus_tag="VVR21_001814"
     CDS             complement(5817..6377)
                     /locus_tag="VVR21_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055621.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            complement(6364..6813)
                     /locus_tag="VVR21_001815"
     CDS             complement(6364..6813)
                     /locus_tag="VVR21_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEU6055622.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7226..7621)
                     /locus_tag="VVR21_001816"
     CDS             complement(7226..7621)
                     /locus_tag="VVR21_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU6055623.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7717..7971)
                     /locus_tag="VVR21_001817"
     CDS             complement(7717..7971)
                     /locus_tag="VVR21_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU6055624.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7981..9315)
                     /locus_tag="VVR21_001818"
     CDS             complement(7981..9315)
                     /locus_tag="VVR21_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU6055625.1"
                     /translation="MVDERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSESGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9315..9548)
                     /locus_tag="VVR21_001819"
     CDS             complement(9315..9548)
                     /locus_tag="VVR21_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU6055626.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9816..9956)
                     /locus_tag="VVR21_001820"
     CDS             complement(9816..9956)
                     /locus_tag="VVR21_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055627.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9953..10135)
                     /locus_tag="VVR21_001821"
     CDS             complement(9953..10135)
                     /locus_tag="VVR21_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055628.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(10137..10920)
                     /locus_tag="VVR21_001822"
                     /pseudo
     CDS             complement(10137..10920)
                     /locus_tag="VVR21_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11305..12210
                     /locus_tag="VVR21_001823"
                     /pseudo
     CDS             11305..12210
                     /locus_tag="VVR21_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3627 a         2684 c         2249 g         3650 t
ORIGIN      
        1 taaaatgcga cagaaacgaa aataaaggag acgttggtaa gaaggcagag aatctcattc
       61 aaggccaatt tgaaggatct aaaacaatgg aaaagtgcta cacagatgtg acagaatttg
      121 ccattccagc aagtactcaa aagctttact tatcaccagt tttagatggc tttaacagcg
      181 aaattatcgc ctataatctt tcaacttcac ccaacttaga acaagtacaa acaatgttgg
      241 aacaggcatt cacagagaag cactacgaga atacgattct ccatagtgac caaggctggc
      301 aataccgaca cgattcttat catcggttcc taagagtaag ggaattcaag catctatgtc
      361 acgcaaggga aacagccaag acaacggtat gatggagtcc ttctttggga ttctgaaatc
      421 ggaaatgttt tacggttatg agaagtcgtt tcagtcgctt aagcaattgg aacaagctat
      481 tgtagactat attgattact acaacaataa acgaattaag gtaaaactaa aaggacttag
      541 ccttgtgcaa tacagaacta aatccttcgg ataaattatt tgtctaactt tttggggtca
      601 gtacacctaa aactttgatg atatacgttt tcttgtgaga atatttactt catttttgcc
      661 taaaattcaa tgtttactca gtatttggat tatgaaaaat cgaggtctaa atctagatac
      721 attttttctg aagacaaatc attttgacca ccgagcaaga gattttcaaa aaaagctgtt
      781 aaaaactcag aacgtcgctg taaaatcttt gcattatcta ataccaaggc atcacgaaaa
      841 tatttggaat gttgctgaaa tggtgtatta tcaatatcaa aaccaaactc acgaagatac
      901 tgaatcaaaa agaccgttac tgtccgagtg tttccttcgc gaaatggatg aatctgccag
      961 attcctgaaa taaaatgctg gatttgttta accacatccg cctgagttag tgtcgcatat
     1021 gcaacttgtt tttcctgatt aaaatcataa tctaaggtca tttgaatcat ggagtaatca
     1081 gagtacacaa cactttcacc attcaaaaca ggttcattct ttgtgatatt ggtctgacga
     1141 aattgcccca ccggaataga gggttcaaat atatcttgaa acaactcctt atgaatagca
     1201 agtaaggtcg caggactaaa gctaaagcct cttcgagaca atagttctac aatacgtaga
     1261 gaaaccaagt ctgcctcttc cgtacttgca tcaatagtat ggtgataagc cgttgcatcc
     1321 tcataaacct gctcataagt cagttctccc cgggactgtt tctcagccaa agattccata
     1381 tacgctgatg gcactagatt gtcaactttc tgcagaccaa aacctatccg ccataaatca
     1441 cgcttcgctt cataagacaa gtttggattg tcaatgttgt aagttgattg catagaaata
     1501 tcctttcaat tgtttttctt cattaccagt aaatcacgaa attggttgga aactggctta
     1561 aactataaaa agtcctcaca ataggttcta tgatatatat atatacttca tgtaaataat
     1621 aaaagagtta taatcagcac tactgataaa ttcaataccg atttcgccat cttaaaactt
     1681 agtcaaacga ataccgttga tttccagttc attaagtcgt tgacctgtca agacttctcg
     1741 ttccttcaac tggaaaagtt aagggggaac taatacaaat cctctacgct tctatattca
     1801 atgatttcat ttttgataat attcttttta aactcaaaat gttttaaagg attatcgatt
     1861 aacactaact ttggaatatc atctagattt gtgaccaagg ataaaataaa atccgattga
     1921 aactccttga ctttttcaaa ttcttttgca gttaaacgca cacgcccctt agattttcgg
     1981 atacctttta cttcggcaag gtaagaatac tcttggacat ctacctgaaa gtcatatcca
     2041 tcaccataaa gacgggcatc ggttaactgt ccaccttgga atttttcttc tttatcaaaa
     2101 tgaaggataa aataattctc agcctccatt cccgtttcct gtagacgttt gaatttagtt
     2161 cgaactattg gtttttcaac gatggttatg cctgttttct tcccttcact ggcaagtaac
     2221 attttaacta tttcagcata actatgaaca tcttcatttc caaacatcat atcaattaaa
     2281 tctttacgaa aacgataaac ttcagctttc tgccaccaac cttttcgatt attgtcaaaa
     2341 taaggatcaa ataaatccat tctatttttt acaactccag ttgtttcagc aattcccaga
     2401 gaaaccacat agcgataaaa ctccgacttg ctagagcatt gaaattcttt tataaaaagc
     2461 ttgtcaaact tggcaagacc gtaaccaatt aaatttaaca attcataatg agggtgtttg
     2521 gacatcactt tctccatcaa tagatattga tttcattata ccaaaaaaca cggctcatca
     2581 ccgtgtttct gtgtttattt caccaacttc ttcatctcat caatacgtgc tacggtcgca
     2641 tcatacttag cttggtaatc tgcttgcttg tcgcgttctt tttggacaac ttctggttta
     2701 gcgttggcga cgaagcgttc gttgctgagt tttttgccaa ccatgtcgag ttctttctgc
     2761 catttggcaa gttctttttc cagacgtgcc aattcttctt cgacattcaa gaggtctacc
     2821 agtggcaaga agatttcggc tcctgtgatg acgcttgaca tagccagttc aggtgcaggg
     2881 atggttgatg cgatttccaa gtgttcagga tttgtgaaac gtttgatgta gttgacattg
     2941 ctgttaaaga aggcttccaa gtcgctatcg cttgtcttaa caaggatagt gataggcttg
     3001 cttggagcaa cgtttacttc cgcacgcgca ttacgaacgg cacggatcaa gtctttaagg
     3061 ctttccacac cagtgtgagc agcaaggtct tcaaaggctg ggttgacagt tgggtattct
     3121 gctgtaacga tagatccttc tgagatttgt ccaaagattt cctctgtcac aaatggcatg
     3181 attgggtgaa ggagacgaag gatcttgtcc aaagtgtata gtagaacaga acgtgtgatg
     3241 actttctctt cttcgttatc gctataaagg acttccttgg tcaactcaac ataccagttg
     3301 gcaaattctt cccagatgaa gttgtaaagg atatgaccag ccacaccaaa ctcgaactta
     3361 tcaaagtttt cagtaacttt tgcaatggtt tcgttgagat tgtggagaat ccagcggtcc
     3421 gtcacattac cagcctcacc tgttgcaact tttgtgacat tgtcatgcgc cacatccagc
     3481 gtcaaacctt cattgttcat gaggatatag cgagaaatgt tccaaatttt gttaataaag
     3541 ttccatgaag catccatttt ctcgtaagag aaacgaacgt cttgaccagg agctgagccg
     3601 tttgacaaga accaacgaag actatctgta ccatatttat caataacatc cattgggtca
     3661 atgccatttc caagagattt agacatctta catccttctt catcacgaat tagaccatgg
     3721 ataaggacgt tttggaatgg ttgacggcct gtgaattcca atgactggaa gatcatacga
     3781 gacacccaga agaagatgat gtcgtaacct gttaccaagg ttgaagttgg gaaataacgt
     3841 ttaaagtctt ctgagtcgac ttcaggccag cccatggttg aaaatggcca gagggcagaa
     3901 ctgaaccaag tatccaagac gtcttcgcct tgagtccatc cgtcaccttc tggagcttct
     3961 tcgccgacat acatttcacc atcagcattg taccaggcag ggatttggtg accccaccaa
     4021 agctgacgag agataaccca gtcgtggaca ttttccatcc attgaaggaa ggtatcgttg
     4081 aaacgaggtg ggtagaattc gaccttgtcc tctgtgtctt ggttggcaat ggcgttctta
     4141 gccaattggt ccatcttgac gaaccattga gtagacaagc gtggctcaac tacgacacct
     4201 gtccgttctg agtgaccgac tgaatggaca cgtttttcga ttttgacaag ggcaccgatt
     4261 tcttccaact tagcaacgac tgccttacga gcttcaaaac gatccatgcc tgaaaattca
     4321 aaggcaagct cattcatagt tccgtcgtcg ttcatgacgt tgacttgtgg caagttatga
     4381 cgttggccaa ccaagaagtc atttggatcg tgggcaggtg tgattttcac gacaccagta
     4441 ccaaactcag gatctgcgtg ctcatctcca acgattggga tgagtttatt agcgattgga
     4501 aggatgacgt ttttaccaat caagtccttg tagcgcgggt cttctggatt aaccgcaacc
     4561 gcaacgtccc caaacatagt ctcaggacga gttgtagcaa cttcaagggc gcgtgaacca
     4621 tcttccagca tgtagttcat gtggtagaag gcaccttcga catccttgtg aatcacctca
     4681 atatcagaaa gggctgtgcg agctgctggg tcccagttga tgataaactc accacggtag
     4741 atccagcctt tcttgtaaag gtccacaaag accttacgaa cagcttttga caaaccttcg
     4801 tcaagagtga aacgctcacg agagtagtct acagagagcc ccatcttgcc ccattgttcc
     4861 ttgatagtag tggcatattc gtctttccat tcccagactt tcgtcaagaa agactcacga
     4921 ccaaggtcat agcgggaaat gccctcacca cgcaagcgct cctctacctt agcctgagtg
     4981 gcaatccctg cgtggtccat cccaggaagc caaagggtat caaaaccttg catgcgtttt
     5041 tgacggatga taatatcttg caaagttgta tcccaagcgt gaccaaggtg aagtttacct
     5101 gtaacgtttg gtggtggaat aacgattgaa taaggcttag ccttttgatc gcctgaaggc
     5161 ttgaaaacat cagcatcaag ccatttttgg taacgaccag cctcaacctc ggctggattg
     5221 tatttagatg aaagttcttt agacatgtgt gtgtcctttc tctattttgt ttattttatt
     5281 ttgaatttgc ttagcagctt cttctgcaga caaattcgta ttatttattt taaagtagtg
     5341 gtgcaactca ttcggttgat attgggaatt taattgaagt gtttcagcgg tctctaaaat
     5401 ttctctttca gatacctcaa tatgtcgttt taagggtttg tgctttaatc gattctccgt
     5461 tcgatttcga cgtatgcact cttcaagact tgtttccaac tcaacaaaaa gaatctcttg
     5521 atgataatca tccaacaaat tctgaatttg ctttaaatat atcagatgat actgatttga
     5581 aaaatcaatt acatctgtta aaattactga tcgctgattt cttgcacttg ctccaaggaa
     5641 tgaaaaagtg attccacgaa caaattccca catttcctct gtatagtcct gatagatttc
     5701 tagtgcaaaa tcaatggctt gatggttata aaatagggta gcatccgtca gtcgagataa
     5761 ttcttgacca atggtcattt ttcctgatgc tggagcacca atgatgaaaa gatgcatcaa
     5821 atcacccccc actcactctt cagcaaggca tatctcaaat catcacagca gttgccttga
     5881 gcatctttac ggtctcttat gcgagcttcg agggtaaagc caagcttttc cgcgactcgt
     5941 tgactttgaa ggttatatcc aaagcaagtt agttcaatct tgtgaagacc caaatcttta
     6001 aaggctaagt caatcaaggc acgcgcagct tctggcacat aacctcgccc ccaatagtct
     6061 gagtgtaagg tatagccgat ttccatcaca tcatcttcat ggcgatggtt gaaatagata
     6121 gagccaacga tcttatccgt tcctttgacg acaatcccgt agcctgctgg gagattttcc
     6181 ttttgattac gctccggaag aatgtgctcc agataataaa tctcatcttc caaggtcttg
     6241 actggaggaa aacctgctgg ataggcgacc tctggcaaac tagcatagtc aaagatatcc
     6301 tcagcatccg ccacagtacg gactcgtaaa acgagacgtt ctgtttcgat tttatctggc
     6361 agctcagttc ttgccatcct tcttcctcgc ttttttgatg aaactgccct tcatatctac
     6421 acgcttgtcc agatagcgat aaacgcgctg atatccatct cccatgaaat atgttggggc
     6481 aaacagttga tttttaaaat gtcccttttc atccaggagt tctggggcaa caagtcgctc
     6541 aagaatcttg gcaaagatgt ggcaaatacc gtcttcctca acaatcctat ctacccgaca
     6601 atctaaaaca agtggacagg cgtctaaaat aggagtctga gttcgttcag aaatttcata
     6661 atgcactccc aaacgttcca atttctcctg atgactgata aaaccagcct gctccatcgc
     6721 aagcatagaa gtttcatcag aaatattcac agtaaatttt tgatactgtt tgatctgctc
     6781 tgcggcattc tctctcgcaa cgactccaat cacaacccaa tctcctagac tataagagga
     6841 actacaggtc gtgatgttat agccaaaatt ctaatcttga tatcctaaaa taaaaacagg
     6901 aaaaccataa tatagtttac ttgtgttaaa agattgcttc ataacaaccc cctttgacta
     6961 agacgtaaaa gaaaagccct gccatctaca tgacagggac gaatctgttt atccgcggta
     7021 ccacccaatt tcgggcagtt gcccgcaact ctcgtcttta aagcaaaaag acacttttat
     7081 ttcaattttt catccattag caaccagttt tgacacattt gtggacttct cagcgccgcc
     7141 actttctgta aaatgtggga ttcaaaacac ctctaatggc tctattgtag caagattttt
     7201 tcggaaatgc aaggctcaag aaaaattact tgaacttgat gccattttct ttcaatttct
     7261 tgatggtagc tgggccgatt cctttcaagt caaggagttc tttttcagtc cagtttttga
     7321 aatctgaagc agacttgatt ccttcatcat agaaagtctt ggcacgatca agtggaagtc
     7381 cacccaaatt tgctgcaaaa tcttctacag aattagctac tttttgagct tgctctttgg
     7441 tagcttctac tgcttgttca acttttttag aaacagcctt accagctgcg cttgctgact
     7501 gttctgcacg cttcacgact ttttttgtct catctacaac cttagtcaca gtacttgaaa
     7561 aggcacctgc gcgacggagg ccatttcgta attgtttttt acgattgagt ttctttgaca
     7621 tgataaaatc ctttcaataa aaaatccctg ctctgacaag gatttaacat aaacattcta
     7681 tcaagatttt agtgaaaaat caagaatctt tctcgtttaa taatttcgct caccaaacaa
     7741 gccttctggc aaatcatgga atcccttgcc tactttgaag ttttcaaact taccaagcaa
     7801 gaactgataa gcatccaagc gactctcgta gcgaatcatg gcatctttgg cacgctcgtc
     7861 ctggtcttct tcgtaaactt tttgactttc cttgtgcgcc atatcgttaa tcatgatttg
     7921 ggtattgacc caagcttcaa attccttcat aaattcttgt tcgtaactca ttttttctcc
     7981 ttattctaat ccacgaaaat agtccgtatc aatctcacgg tagggctgga tatcctgaac
     8041 atactccaac actccttgga attctccgtc ttcatcgtgt actgcagcat aggtgatgtg
     8101 gacaaactta cctcgcgact cagacttgaa ccacatttca tacttgtctt tgcttccctc
     8161 acgaagcccc ttcatgatag ttttgacctt gtccaagtac ttaggcggat ggcagagttc
     8221 gacattgcgc ccgacttggg acggtgtccg tttgaaaatc atctcatcag ctggcgtatt
     8281 gtcattgtaa tactggaaaa tatcttcttt attgacaaag gtaatctcca tagggagatg
     8341 attgaggatg agattggcct gctcgactga aagatagcca ttaccaaaag cctgttgact
     8401 atggcggtcc agcacagctt ccttttcctt aggggtaaag gtaatggtaa aatggccttc
     8461 tggcgtatct atgacttgtt gaacttgacc ttctgccgta tctagctgta caggttcctc
     8521 tgcaatcttt tcctcaataa agctctgtcg ttctggcacc catttctctg acggacggat
     8581 gatggcatag ccataggcat cgctctcctc cgcaatctga agccagtcat cctgagtaaa
     8641 agactcaagg agaatcatga ggaggatgga ctcttccttg aaaatcatac tttcaaactc
     8701 tgtcgcaaaa gcttcaaaag cttcctttac actgctaatt gacacttctg gtagtgactt
     8761 ggctgtcgtt agagctgttt gaaagagttc cctaatctga tcatccactc cccacataac
     8821 tttgggaggt gaatcgtgtc catagcgctc catgatagga aagaagagtt cttccttacg
     8881 ttggtaatgg atgtcaaatt gacccacaag tcccatctga cgcaccaaac ccttacgcat
     8941 ctccgccagc atttcctcgt cttccataga ctcataggta tctaacaatc tacgaatgcg
     9001 aatcaaggcc gcacggagag ccagattttc ttctttgaag acacgaactg ggtgacctgg
     9061 atgctcagta tctgaaactt cgacaccttt gatagcattt ttaaaaagat tggcatggac
     9121 atcacagagt tccataacat cttcaaaggt gacacctgac tctgagttca tcagctcgtg
     9181 ctccataagg gaaatctcaa tggctgagac acccgcaaag gtcgcatcaa aacgctcctg
     9241 aaccgactca ggagaggcgc cattatgcaa ttctaataaa atatcccgta ggacatgaat
     9301 ccgttcatct accattagtc taatccaatc acttcgtagc cattcgcttc cagtgtgcgt
     9361 acaatcttgt ccataggagt tcctgctagc ttagaacctt gtttaagtga tactttacga
     9421 ccaactgtat tgcgcatcaa gggattggca aggggtttaa aacccagctc cactagaatt
     9481 tccaagactt ctggatgctt gtccaccact tctgcaacag gaattgacac atcgatgata
     9541 ttgtccatga cgacctccat tgtatgttct aatactcaat gaaaatcaaa gagcaaacta
     9601 ggaagctagc cgcaggttgc tcaaaacacc gttttgaggt tgtggataga actgacgaag
     9661 tcagtaacat atatactgca aggtgaagct gacgtggttt gaagagattt tcgaagagta
     9721 taaaatgatt ttactgctta tattatacca tatggagaga gattaaaaaa ctagcagtgg
     9781 agttcctgct agttttctgc gacttggatt accatctaga taagtttaaa gaaccaatcc
     9841 aatatcttgt aaaacagcaa ttgaactgca aaagaaatga tcatccaaaa gaatttcaca
     9901 atcccaataa tcggtttgat aaaaagaata gcaagaattg tccagaaaaa tttcattctc
     9961 tctcctctgg cttaatgagc caccgagccg tatccattag cttatctgca ataaagagtt
    10021 ttcccagacc aacaacgaca tggtcatctt tctttatcgt tttcatcact tttacacctt
    10081 gcacggtcaa aaagtaatta ccataaattt tagcaaaagc tttgatagga ttcatattat
    10141 tctcctttga tgatttcagc ctcttttcgg attgtttcaa catcttcttg atattgaact
    10201 tcactatagt tgactagctt ggataattct ttctgcaagc tttcccccat tggtttcata
    10261 gttgcaaagg ttaaaccacc tgaaatgata ccacccaaga taggaataaa tttccccatt
    10321 cctttggcca accctccctt ggtaagattc acaccaaata tttttaagac ttttttcaaa
    10381 atagggtacc aaagcgtctt tgttaaagct ttattaggca ctgttttcat tacctgtttg
    10441 gcaattgtta taccaccagc acgtagcaaa caaagcagcg gttccattca cccctaacat
    10501 tacgcctaga taaagcaaga gggtattttg agcatcttca ctcaactcct cacgtgaagc
    10561 ccaaagatcc tcataaccat aaatataacc taattcttgg gccaatttca gagagaaacc
    10621 ataaaattga gccacataag ctggaatggt aattgccata gcaagccctc caggtaatcc
    10681 tgccaaaaca gaagtcccac tcgctaataa aacattatcc ctaatacagg cattagccac
    10741 tcgatctaag atttcttgag ataagagaga cgttggacct tgttccaata aggtaggaat
    10801 gtcctgtgga cccaattctt tggaaaactt atccactaaa aatttcgaac gatcaacctt
    10861 aacaactggt agttttacca cttgttgtaa tacttgcata gctaagtctt gttcagccat
    10921 atacaaactc cttatttctt ttttgcacct tatcatatta tatttcctac aaaaaaagca
    10981 ttttctaatt agataacatt aaaaaataca gaaccccttt tttatagtaa aataaaacaa
    11041 gaacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag
    11101 gcgtactatt ctagtttcaa tatattttaa aagaatattt ttccatttca aattcaacct
    11161 attttcctcc accaaaaaag ggctctataa tatttgtagt gggtaaattc cctatggata
    11221 ttatggagcc tatttttgtg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca
    11281 aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa actgctcgat
    11341 attaaagacc caaacatcaa gattctagat atcatcaata aagatacaca caaagaaatc
    11401 atcgccaaac tggactacga cgccccatct tgccctgagt gcggaaacca attgaagaaa
    11461 tatgactttc aaaaaccttc taaaattcct tatcttgaaa cgactggtat gcctactaga
    11521 attctcctta gaaagcgtcg attcaagtgc tatcactgtt caaaaatgat ggtcgctgaa
    11581 acttctatag tcaagaagaa tcaccaaatc cctcgtatca tcaaccaaaa gattgctcaa
    11641 aagttaattg aaaagaattc tatgaccgat attgcccatc agctggccat ttcaacttca
    11701 actgtcattc gaaagctcaa tgacttccac tttgagtgta attttagaaa tctgcctgag
    11761 attatgtcct gggacgttga aacagtccgg ggagtgactg tttcaatcgg gagatggaga
    11821 tgagctttat tgcgcaagat tttgaaaagc tcgatatcat cactgttctt gagggtagaa
    11881 tacaagctgt catccgagat cattttctta agtatgatag agccgtccga tgtcgcgtca
    11941 aaatcattac tatggatatg tttagccctt actatgactt ggctaaacag cttcgctttc
    12001 aaatttctag gctcaggctg aaacagtctc ccagactgtt tcactcccga atgctaaaat
    12061 cgttcttgat cgctttcaca ttgtacaaca tcttagccgt gctatgagtc gtgtgcatgt
    12121 ccaaatcatg aatcagtttg aacgaaaatc tcatgaatac aaggctatca agcgttactg
    12181 gaaactcatc caacaggata gtcgtaaatt
//
LOCUS       DAVHSI010000050        11794 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.051, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000050 DAVHSI010000000
VERSION     DAVHSI010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.051"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(40..993)
                     /locus_tag="VVR21_001824"
     CDS             complement(40..993)
                     /locus_tag="VVR21_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU6055629.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            complement(1061..2279)
                     /gene="sstT"
                     /locus_tag="VVR21_001825"
                     /pseudo
     CDS             complement(1061..2279)
                     /gene="sstT"
                     /locus_tag="VVR21_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            2418..2978
                     /locus_tag="VVR21_001826"
     CDS             2418..2978
                     /locus_tag="VVR21_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEU6055630.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            3035..3943
                     /locus_tag="VVR21_001827"
     CDS             3035..3943
                     /locus_tag="VVR21_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU6055631.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            3895..4485
                     /locus_tag="VVR21_001828"
     CDS             3895..4485
                     /locus_tag="VVR21_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU6055632.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            4488..5594
                     /gene="yqeH"
                     /locus_tag="VVR21_001829"
     CDS             4488..5594
                     /gene="yqeH"
                     /locus_tag="VVR21_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU6055633.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            5808..6119
                     /gene="yhbY"
                     /locus_tag="VVR21_001830"
     CDS             5808..6119
                     /gene="yhbY"
                     /locus_tag="VVR21_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU6055634.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            6171..6800
                     /locus_tag="VVR21_001831"
     CDS             6171..6800
                     /locus_tag="VVR21_001831"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU6055635.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            6800..7393
                     /gene="yqeK"
                     /locus_tag="VVR21_001832"
     CDS             6800..7393
                     /gene="yqeK"
                     /locus_tag="VVR21_001832"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU6055636.1"
                     /translation="MSYQDYINCSREVLLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            7394..7894
                     /locus_tag="VVR21_001833"
     CDS             7394..7894
                     /locus_tag="VVR21_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU6055637.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            7907..8260
                     /gene="rsfS"
                     /locus_tag="VVR21_001834"
     CDS             7907..8260
                     /gene="rsfS"
                     /locus_tag="VVR21_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU6055638.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            8363..9109
                     /locus_tag="VVR21_001835"
     CDS             8363..9109
                     /locus_tag="VVR21_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU6055639.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRLSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            9119..10216
                     /locus_tag="VVR21_001836"
     CDS             9119..10216
                     /locus_tag="VVR21_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU6055640.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKYLKGQVSLVSRIGKEPWDV
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            10563..>11794
                     /locus_tag="VVR21_001837"
     CDS             10563..>11794
                     /locus_tag="VVR21_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU6055641.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQI"
BASE COUNT         3683 a         2166 c         2655 g         3290 t
ORIGIN      
        1 tatatacagc aaggtgaagc tgacgtagtt tgaagagtat tactgtccat atttttgata
       61 aaagtcaact tttacttgga tgaaggtttt ggcttcacgt aggagttgga gaagggtggc
      121 gcgggtttca aattcttctc ttgtcttggg cagactgcgg ttccggaaga cttccagata
      181 acgttcaatt tcatctagca aatcagaggc aggattggtc tggctcagtt gaccagcaat
      241 ttttgaaaag agctgcgcta aaatcaggct ttcactggcg gcaaggtgac aagtgttaat
      301 ctgttgggcc atgtttctca ggatacgact ttgtcgttgt ctcatctcaa agtagtggat
      361 atggtagtcg gtctggtgaa agaggtggtc agagtgatcc aaatagacca gtctgagggc
      421 ttctttcaaa agcgtgtcta attctgctac cagctgtgct cggttgcgtc cgtctcctct
      481 ggataaatag tatttgaagc gctggaggat atcttttaac ttttcttcca ccagcgtgtg
      541 gtagtgctgg atttcctctt ctcgtgaagg catatagaga ttaacaagca aggcaaatcc
      601 tgtaccaata gcaaagagaa ggaattcatt gactagaagg tctggagagg ttgactcttg
      661 aaccaagaga tgactaacca aaaccgtgct tggtgtgatg ccaatttccc agcccatctt
      721 gtaggctaaa ggaacgtaga aggccagata gaggccgaga ctccagatat gaaatccgct
      781 caagtgaaaa gctagaacac cgatagccag agctagaagc atagaaaaaa gacgattgcg
      841 agccagtttt aaagtacttc tacgcgtatc agataggctc aagagagcga taattccagc
      901 tgaaactgct gacgaaagat tgagaaaata agcaagcagg caggcaagac aggtagctaa
      961 gatgagcttg gtcgtacgtt ggctaataga cataagaatt tcctaataag ttagaataaa
     1021 agcgtaaaag acaagacatg agcaggcttg ccttgatgag ttatttttta cgggttgctg
     1081 cgtattcggc aacggcggta aagaggacat ctgtagaaga gttaagggct gtttcacatg
     1141 agtcttggat gacaccaatc acaaaaccaa ccccaacaac ttgtatggca atatcgttag
     1201 aaataccgaa aaggctacaa gcaactggga taagaaggag ggaacctccg gcaatacctg
     1261 aagcaccaca ggctgagata gctgctacca cactgaggac aaaggctgtg gcaaagtcaa
     1321 caggaattcc aagagtgtta actgtaacaa gggtcaaaac gttaatggta atcgctactc
     1381 cagccatatt gatagtagaa ccgagtggga tagaaacaga ataggtatct gggttgagtc
     1441 caaggtcatg gcagagtttc atgttgacag gaatgttagt cgcagaacta cgagtgaaaa
     1501 aggctgtcac accgctgaca cggaggcagt tccaaactag agagtaagga ttgcgtctca
     1561 taaagaagaa ggtaatcaaa gggttgacca caggggcaac aaaaagcata gtcgttacta
     1621 atggaaccaa taaaataccg tagttggcaa ggcttccgac tcccttgtca gaaatggttt
     1681 taaaaacaag accaaggatt ccaaatggag ccagattgat gatccattcg acaattttag
     1741 aagtcacgtc agcgatagtt tttagcaatt ctttactatt tttactggtt ttactggctt
     1801 ctctcatagc gattccaaaa atgactgccc aagataagat tccaatatag ttagcagtaa
     1861 gcagggcgtt gactgggctg tcaaccagtt tgagcaagag gttgctgagg acctgcccaa
     1921 tcccatctgg tggtgcaatt tcagtattgg cactatttag ggtaatttca atagggacga
     1981 tgaaacttgc tagtacagct acaagagcag cggcgaaagt ccctatcata ggatatacaa
     2041 gaaaacaaca gttttcatat tgctatcttg tcccttttga tgttgggaaa gggcattggc
     2101 aacgagggca aagactagga taggagcaac agcttttaga cctccaacga ataaatcccc
     2161 gagtagccca atccctgaga gattaggaag ggtcagtcct aggattcccc ataaagcata
     2221 ccaatcaaga tacgcttgac aaggcttgct ttattccaag catgaatgat tcttttcata
     2281 ataatctcct ttttgtgtag tgattatgat tatagtataa atgatagaca aaatcaagaa
     2341 ttttctgtct attttttgaa tatttatgga gaatgagact gatgaaaata tggtataatg
     2401 aaataaagga gttttatatg caaaaattta ttcaggctta tattgaaaag ctagatgtga
     2461 caaccattat cgagaatatt ctaaccaagg tcatttctct tttactgctt ttgattgtat
     2521 tttatattgc taaaaaaatg cttcatacca tggtgcagag aattgtcaaa ccttctctaa
     2581 aaatgtctcg tcatgatgtt ggacgccaaa aaaccatctc acgtttacta gaaaatgtgt
     2641 ttaattatac gctatatttc tttttactct actgcatttt gtcgatttta ggtttgccag
     2701 tttctagttt gctggctgga gctggtattg ctggggtagc gattggtatg ggagcccaag
     2761 gctttctatc tgatgtcatc aatggctttt tcatcctctt tgaacgtcaa ctggatgtgg
     2821 gagatgaggt cgttctgaca aatggaccga ttactgtatc gggtaaggtt gtcagtgtgg
     2881 gaattcgtac gacacagctt cgtagcgagg agcaagtcct tcactttgtc cctaaccgaa
     2941 atatcacagt tgttagcaat ttctcacgca cagactagac ctgttatttt aagtaatttg
     3001 tggtacaata gagggagttt aataaggaga aaagatggtt ttagaaaagc agttgggcaa
     3061 tggttgtacc tggatagacc tagacctagg aaagttgaat aaactagaag acctttctga
     3121 aatttacggt ttggacaagg aaaccattga atacgcactg gatagaaacg agcgcgccca
     3181 catggactac caccgtgaaa gtgggacggt tacctttatc tataatgtcc tagacgtaaa
     3241 aaaggacaag gcctactatg agacttttcc catgaccttt attgtcgagc atcgtcgcct
     3301 gattaccatt agtaatacca agaacgccta tgtcattgaa cagatgactc gttatctgga
     3361 aaaccatgac acgctttcga tttataagtt tctctttgcc agtctggaaa ttatcagcaa
     3421 tgcctactat cctgtcattg agcagatgga caagagtagg gatgaggtca atgacctctt
     3481 gcgccagcga actaccaaga aaaacctctt tgccctgtct gatttggaga ctggtatggt
     3541 ttatctgacg gcagctgcca aacaaaatcg gattttgtta gagcatattc aaggtcatgc
     3601 cttgtatcgt agttttgatg agattgagag agaacagttt gatgatgcca tgattgaggc
     3661 tcatcagctg gtatccatga cagacctaat ctctcagatt ttacagcagc tttcagcctc
     3721 ttacaacaat attctaaaca ataatttgaa tgacaatttg acaaccttga ctattatttc
     3781 agtcttgcta gctgttttgg cagtcgtgac aggctttttc ggaatgaatg ttcccttacc
     3841 tttaacagat gagccccatg cttggctcta tattagtttg gctagtgcag gtttgtggat
     3901 tgttttatcc ttgttactaa ggaaaattgc gaaaaaaagt taagaaaagg agccagaatg
     3961 gcgattgaaa attatatacc agattttgct gtggaagcag tctatgatct gacagtccca
     4021 agcctgcagg cgcagggaat caaggctgtt ttggtcgatt tggataatac cctcattgct
     4081 tggaacaacc ctgatggaac gccagagatg aagcaatggc tacatgacct tcgggacgcg
     4141 ggtattggca ttatcgtagt gtcaaataac accaaaaaac gcgttcaacg agcagttgag
     4201 aaatttggta ttgattacgt ttactgggcc ttgaagccct tcacatttgg tattgaccgt
     4261 gctatgaagg aattccacta tgacaaaaag gaagtggtca tggttggtga ccagctcatg
     4321 acagatatac gagcagccca ccgtgcaggg attcggtcaa ttttagtcaa acccttggtc
     4381 caacatgact caatcaaaac gcagattaac cgaactcgtg agcgtcgtgt tatgagaaaa
     4441 atcactgaaa agtacggacc gattacatat aaaaaaggaa tttaactatg gaagaaattc
     4501 tctgtattgg ttgtggagca accattcaga cgacagataa ggctggtctt ggttttaccc
     4561 cccagtcggc acttgaaaaa ggtttggaga ctggcgaagt ctattgccaa cgctgtttcc
     4621 gtctccgcca ctacaatgaa atcacagatg tccagttgac gaacgatgat ttcctcaagc
     4681 tcttgcacga ggtgggagac agtgatgctt tagtggtcaa tgtcattgat atctttgatt
     4741 ttaatggatc tgtcatccca ggtttaccac gtttcgtctc gggcaatgat gtcctcttgg
     4801 taggaaataa aaaagatatc cttcctaagt cagttaagtc tggtaagatt agccagtggc
     4861 tcatgaaacg tgcccatgaa gaaggtcttc gtccagtcga tgtggtccta acttcagcac
     4921 aaaataaaca tgccattaag gaagtcattg ataagattga acactaccgt aagggccgcg
     4981 atgtctatgt ggtcggtgtg accaacgttg gaaaatcaac tctaatcaat gctattatcc
     5041 aagaaatcac gggtgatcag aatgtcatca ctacttcacg ctttccaggg acaaccttgg
     5101 acaaaataga gattccgctt gacgacggat cttatattta cgatacgccg ggaattatcc
     5161 accgccacca gatggctcac tacttgacgg ccaaaaacct caagtatgtc agtcctaaaa
     5221 aggaaatcaa gcctaagacc tatcagctta atcctgagca aaccctattt ttaggtggtt
     5281 tgggacgctt tgactttata gcaggagaaa agcaaggatt tactgctttc tttgataatg
     5341 aactcaaact ccatcgtagc aagcttgaag gagctagtgc tttctacgat aagcacctgg
     5401 gaactcttct gacaccacca aatagcaagg aaaaagaaga tttcccaagg ctagtccagc
     5461 atgtctttac cattaaagat aagacagacc tagtcatctc aggcctaggc tggattcgtg
     5521 taacaggcat agcaaaagtc gccgtctggg caccagaagg cgtcgccgtc gtcacacgaa
     5581 aagcaattat ttaaaacaaa atcgctgagc gaacaaagtg agctcatata gcgatagtta
     5641 ttgccgtggt gtgattgcca atctgtagat tggcaagggg cacaattgag accaaggctc
     5701 aattgtgagg tcaggaaatc catttttcaa agatgaaatc tttggaaaat tagttccgac
     5761 cgtccctcac cacctaaaat aactatcaaa aaacaaggaa gaaaattatg tcattaacat
     5821 caaaacaacg tgccttcctc aacagccagg cacacaccct caaacctatc atccaaatcg
     5881 ggaaaaatgg actcaacgac caaatcaaaa ccagcgtccg tcaagctctt gatgcgcgtg
     5941 aattaatcaa ggttactctc ttacaaaaca cagatgaaaa catccacgaa gtagctgaaa
     6001 ttttggaaga agaaatcggt gtggatacag tccaaaaaat aggacgcatc ttgattttgt
     6061 ttaaacaatc tagcaagaaa gaaaatcgca agatttctaa gaaagtcaaa gaaatctaag
     6121 accgaaactc caaataactg tttttataga gaaataaagg ggactagcct atgacaatcg
     6181 aactattgac tccctttacc aaggtagagt tggagccaga aatcaaggag aaaaaacgca
     6241 aacaagttgg gattttaggg gggaatttta accctgttca caatgcccat ctcattgttg
     6301 cggatcaagt acggcaacag ttgggactgg atcaagttct tctcatgcct gaataccaac
     6361 ctcctcacgt tgataaaaag gaaaccatcc ctgaacacca tcgtctcaag atgcttgagt
     6421 tggcaattga ggggattgac ggcctagtca ttgaaaccat tgagttggag cgcaagggta
     6481 tttcctacac ctacgatacc atgaagattt tgacagagaa gaatccagat acggattatt
     6541 actttatcat cggcgccgac atggttgact atctgcctaa gtggtaccga attgatgaac
     6601 tggttgacat ggttcagttt gtgggggttc agcgtccacg ctacaaggca gggacttcct
     6661 atccagttat ctgggtggac gtaccgctca tggatatctc gtccagcatg gtgcgggact
     6721 tcattgccca aggtcggaaa cccaactttc tcctacctca gccagtgcta gactacatcg
     6781 agaaggaggg gctctactga tgtcctatca agactatatc aactgctccc gtgaggtttt
     6841 gttggaaaaa atggcagagc ttctacctga gaaacgtcta acccattgtc taggtgtgga
     6901 gcgtgccgct atggaattag ctcagcgctt tggtgtagat gttgagaaag caagtctagc
     6961 aggtcttctt catgactatg ctaaaaagtt gtcagatcag gaatttctag ccttgattga
     7021 ccgttatcag ctagatttcg acctcaaaaa ctggggtaat aatgtctggc atggtatggt
     7081 cggaatttac aaaattcagg aagatttgga tttgcatgat tctgaaattc tgcgagccat
     7141 tgaagtccat acagtcggtg ctggtcaaat gacagaccta gataaggtca tctacgtcgc
     7201 agactatatc gagcacaatc gagcctttcc tggagtagat gtggcgcgtg agattgcaag
     7261 tctatcgctc aataaggcgg tggcctacga aacagctcgt accgtggagt atctagctca
     7321 tcagggattc cccatctatc cccaaaccct tgaaacctat aacgcctttg tgcactattt
     7381 gaaagagaac taaatgaaga cggcttttat aatcattgat gttcagaatg ttttagtaga
     7441 aactggattc cagacaaaaa gtctattggg aaaaatttct tatttacaaa accaggctag
     7501 aagcaagaat attgaaatta tctatgttca acatattgag aactctgaag ctcaaacatc
     7561 agaagattgg cagttatctg cgcttttaaa tcgaaaacct gctgaaaagg tctttcagaa
     7621 gaagtataac agtattttca aagaaactgg cttaaaagaa tacttggata agcaggggat
     7681 tgaaaaatta gttttatgtg gtatgcagac agaatattgt gtggatacct ctgtcaaggt
     7741 tgcctttgaa tatggctatc agcttattgt tccagaaggt gctgtcacaa cctttgatgg
     7801 ggatgacatt ccagcagaaa cgattaatga attttatgag gacatttggg aggagcactt
     7861 tgcagatgtc ctagattaca aacatatttt ctaaaaagag gattaaatga acgaaaaaga
     7921 attactagaa ctagtcgtga aagcggctga tgagaaacgt gcggaggata tcctcgcact
     7981 tgatgtacaa gatttgacta gtgtgacgga ctactttgtc atcactagct caatgaatag
     8041 ccgtcagttg gacgctatcg cagctaatat ccgtgaaaaa gtagctcaag cgggctttaa
     8101 aggtagccat gtcgaaggcg atgcagctgg aggctgggtc ttactggacc tcggtgctgt
     8161 tgtcgtgcat atcttttcag aagaaatgcg tgcccattat aacctagaga agctatggca
     8221 tgaggcgaat tcagtagata tttcagaagc tcttgcttag aagatgaact cagttgtagt
     8281 caactgggtt tctttgctta ttttagaaaa attgatagaa aggtaaaggg ctagtggtgt
     8341 ttaccatgga gctcttagta tcatgattat ggcgacttat gaaacctttg cggcggtcta
     8401 tgatgcggtc atggacgata gtttatacga caaatggaca aatttttctc tgcgtcattt
     8461 gcctaagacc aaggagaaaa agaaactctt ggaactggct tgtgggacag gaattcaatc
     8521 agtgcgctta tctcaggctg gttttgatgt gactggactt gacttgagtg cggatatgtt
     8581 gaagattgcg gagaagagag caacttcagc caagcaaaag attgctttta tagaaggtaa
     8641 tatgctgaat ttgtccaagg cagggaaata cgattttgtc acgtgttatt cggactctat
     8701 ctgctatatg caggatgagg tggaagtagg ggacgtcttt aaggacgtgt acaatgcgct
     8761 gaatgaagag ggagttttca tctttgacgt gcactcgacc taccagacag atgaagtatt
     8821 ccctggctat tcctaccatg aaaatgcgga agattttgcc atgctttggg atacatatga
     8881 ggacgaagct cctcactcca tcgtgcatga gctgactttc tttatcaagg aggctgacgg
     8941 ttcctttagt cgccacgatg aagtacatga ggagaggacc tatgagatct tgacctatga
     9001 tatcttactg gaacaggctg gattcaagtc cttcaaactc tatgcagact ttgaggataa
     9061 ggagccaaca gaaactagca cccgttggtt ttttgtggcg cagaagtagg agattagcat
     9121 gaccatcaca ggtattatcg cggagttcaa tccttttcat aatggccata aatacctgct
     9181 ggatcaggca gagggactga aaattgttgc catgtcaggg aatttcatgc agcgtggaga
     9241 gcctgctatt gtggataagt ggacaagggc ccagatggcg ctggaaaatg gcgcagactt
     9301 ggtagtggaa ttgccctttt tagtcagtgt tcaggcagct gatttctttg gtcaaggagc
     9361 tgtggatatc ttggatcgct tgggcattga tagtctagtt tttgggacag aggaagttcg
     9421 agattatcag aaaatcgctg acttatacac agagaaaggt gctgagatgg agaaatttgt
     9481 ggaaaatctg cctgattccc tttcctatcc ccagaaaacc caagctatgt ggaaggaatt
     9541 tgctggtctt gatttttcag gtaatacccc caatcatgtt cttgctctgg cctatgcaaa
     9601 ggcggttgca ggacgaaata tcaagctgca tccgattcag cgtcaggggg caggttacca
     9661 ttctgtgaat aaagatgtgg actttgcctc ggcgacagcc ctccgtcaac atcagaagga
     9721 ccaagatttc ttagaacgtt ttatgccttc tgttgcccta tttgagcagg ccagtaaggt
     9781 gatctgggaa gactattttc ccttgctccg ctatcaaatc ttgtcaaatc ccgacctaac
     9841 caccatctat caggtcaatc aagaaatggc tgtgcgcatt aaagaagcta ttaaaacagc
     9901 ccagtctgtg gaagaattgg tcgagttagt gactactaaa cgttacacca aggcgcgtgt
     9961 cagacgccta ttgacctata ttttggtgca ggctagggaa aatgtcttgc cagaagccat
    10021 tcatgtcctt ggctttaccg aaaaaggcag gcaacatctt aaatatctga aagggcaggt
    10081 cagtctagtc agcagaattg gcaaggaacc ttgggatgtc atgactcaaa aggcagacca
    10141 gatttaccaa ttgggaaatc caagtatagc agaacagaat tttggcagag tgccgattag
    10201 aatagaaaca aactaagtct actgaaaggt aggctttttt attgtagaaa ttttagataa
    10261 caaattgaag ataaagtttt tggaaaatga taaactccct aatacagaag acaaaaagtc
    10321 aataaagaaa attagtatat gaaccttaat ctttatcttt gaatccgctt tatgcttgtt
    10381 attttgtggt ataatgaaga gaactggtta tattaaaaat cataaattga atataaaaga
    10441 caaataaatt tttatattta taaaccatga taaacttttg tttaagatta tgtaataaaa
    10501 aagaagattt ataaggataa tttgtattta tgtagtacaa gctaatgtag gatagttaaa
    10561 atatggaaga aaattataat ttatctataa ctcaaataaa gaattctatt aaagaaaatt
    10621 ccttagtttt gtttgttggt gcaggaatat cagctaattc taatctacca acttggggag
    10681 aattgattca atcattaaaa aaagaattga acataccaga agaaagaaca gatagtccac
    10741 tgagaattgc tcagtattat tatgatactt ttgggaaaaa tcagtacaca aagaagatag
    10801 aagaaatttt ctttaagaag ggattgagta aaccaaatga gttacataaa ttaatagaaa
    10861 aaattgcacc aaaacatatt attacgacaa actatgattc acttctggag agtcaatttg
    10921 aaagtggctt gttaaagtac aatgtagtcg ctgaggataa agacatccct tatacgagtt
    10981 cggaaagata cttgattaaa atgcatggtg acttcagtaa gaaaaatatt gttttgaaag
    11041 aagatgatta tttagactat catttgaact tcccaatgat ttctacttta atccagtcat
    11101 tgataatgaa tcatactcta ttgtttgtgg ggtattctct aagtgattcg acttttaatt
    11161 caatttttag aatgattcaa aatacattta aattggatgc taaaaatgct tatttttata
    11221 ctcccgagga accgtctatg atcattcgag agtattataa gaagcaagga attttcatta
    11281 tctctaatga agagaatcta ggtcaggaga catcagaaaa acagaacaaa ttgtattgca
    11341 ggacaaaaga ttttttagag gttctatcag aaaaccgaag tcaagatgta aataatgctg
    11401 atgatttatg gaatcaactg gcttttttag atagacttag ttttattgat gcgaaagatt
    11461 tttctagata ttctgattta aagaaaaggg ctttaaactg ggatgatgag tattgctggt
    11521 ttggaaatga tcaattaaga tttgaaattg atggtcatga agaattacga attatggtat
    11581 ctaaaaaatc tttattaaat cgctttctag atatggagat tggtgaacct agggatttaa
    11641 aggggaatcg attcttaagt aaggctttta agttgtatga agaaaaacaa tattctttag
    11701 caaaagcaaa atttagagaa ctagctaata tagcatttcg tcagaaagac tattttaatt
    11761 tcttagtttg tgaatttaat tttcagcaaa ttca
//
LOCUS       DAVHSI010000051        11775 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.052, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000051 DAVHSI010000000
VERSION     DAVHSI010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.052"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(109..186)
                     /locus_tag="VVR21_001838"
                     /pseudo
     CDS             complement(109..186)
                     /locus_tag="VVR21_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(247..471)
                     /locus_tag="VVR21_001839"
     CDS             complement(247..471)
                     /locus_tag="VVR21_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEU6055642.1"
                     /translation="MIDILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(476..655)
                     /gene="asp4"
                     /locus_tag="VVR21_001840"
     CDS             complement(476..655)
                     /gene="asp4"
                     /locus_tag="VVR21_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEU6055643.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(657..1994)
                     /gene="gtfB"
                     /locus_tag="VVR21_001841"
     CDS             complement(657..1994)
                     /gene="gtfB"
                     /locus_tag="VVR21_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEU6055644.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYADGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYDVLGQAIMTSYRDVDQKEVILENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHYPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINYSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGRQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(1987..3498)
                     /gene="gtfA"
                     /locus_tag="VVR21_001842"
     CDS             complement(1987..3498)
                     /gene="gtfA"
                     /locus_tag="VVR21_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HEU6055645.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTESSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEARKEIPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(3510..5882)
                     /gene="secA2"
                     /locus_tag="VVR21_001843"
     CDS             complement(3510..5882)
                     /gene="secA2"
                     /locus_tag="VVR21_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEU6055646.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGDGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDMIYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(5875..6315)
                     /gene="asp3"
                     /locus_tag="VVR21_001844"
     CDS             complement(5875..6315)
                     /gene="asp3"
                     /locus_tag="VVR21_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEU6055647.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(6312..7847)
                     /gene="asp2"
                     /locus_tag="VVR21_001845"
     CDS             complement(6312..7847)
                     /gene="asp2"
                     /locus_tag="VVR21_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEU6055648.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSEALREIIEK
                     EDINRFHAVLIEDGQYAKDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(7831..9411)
                     /gene="asp1"
                     /locus_tag="VVR21_001846"
     CDS             complement(7831..9411)
                     /gene="asp1"
                     /locus_tag="VVR21_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEU6055649.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFGPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNSQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(9421..10638)
                     /gene="secY2"
                     /locus_tag="VVR21_001847"
     CDS             complement(9421..10638)
                     /gene="secY2"
                     /locus_tag="VVR21_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEU6055650.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSYSKKLGLSSTAIEIQDRR
                     RMYLTLLIAVIQSLAVSLSLPVQSSYSVILVALMNTLLLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSIVLNIPQDVIETFKLVYIPTGIVVLLVFMTIIFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVIMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYRPLI"
     gene            complement(10695..11372)
                     /locus_tag="VVR21_001848"
     CDS             complement(10695..11372)
                     /locus_tag="VVR21_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU6055651.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCILAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(11357..11601)
                     /locus_tag="VVR21_001849"
                     /pseudo
     CDS             complement(11357..11601)
                     /locus_tag="VVR21_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            complement(11601..>11775)
                     /locus_tag="VVR21_001850"
     CDS             complement(11601..>11775)
                     /locus_tag="VVR21_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU6055652.1"
                     /translation="NTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERP
                     DDLVDRMKNIEIE"
BASE COUNT         3814 a         2589 c         1876 g         3496 t
ORIGIN      
        1 gtgttttgag ctgacttcgt cagttctatc tacaacttca aaacggtgtt ttgagctgac
       61 ttcgtcagtt ctatctacaa cctcaaaacg gtgttttgag ctgacttcgt cagttctatc
      121 cacaacctca aaacagtgtt ttgagcagcc tgcggctagc ttcctagttt gctctttgat
      181 tttcattgag tataaaaaag aaaacttcag accaatccac aaaaggtgaa tatctgaagt
      241 tttcttttat ttataagtaa tcaccataaa ggttaatagt agaacaaata aagccaaact
      301 caccaataaa gtgagcacct tgaccaaggt gttgctctgc cagtagcttg gtttaccaat
      361 attactagtg gcatccatgg aaaatagttg attttgacgg ggttgtatag ttaccaatac
      421 aatcaaagca agagatagga taatagctaa aacaattagt atgtcaatca tagatctacc
      481 tcaaaattcc cagcaaagta aagagcaaac caatcagaat catcaaaccc agtaaaagtg
      541 aaaaagtctt actaatcttt tcccctcggg tttctttttc cttcttgatg ggtttttgtt
      601 tcaactcttc catgcggcct tcaacgtctt tgtaaaataa atcttcctct gacatgttag
      661 cctcctaaaa cagtttgcat ggtttcctga tatctcacca agtcaacata atttgcatgt
      721 tggccttgtc tgccaagtgc ctgacgcatt tgatcaacat ctgaaagggc caatttaatg
      781 gtctcaacca aagcagcaac ttcactactt tcaaatagat ggtctggagc gatataaagt
      841 ctattgtgaa ccgtttgatt aaatccaaga atcaagagat tgtgctcaaa ggcctgacga
      901 actgcctgca ataactcatt gctatagttg atatccaagt aaatatccga cagttgatac
      961 aactcctgaa tcttctgtgg actagcattc tggtaaagaa ccacattagg atagcgaagc
     1021 atgtctaaga gcttagaaga catctctgtc accgctgcga tacggaaggt aacatcaggc
     1081 aaggcttcta cgattgcttc tacttgctca atctgatctg aattggtcaa gattaaggcg
     1141 tctcgtctta ggaaattatc acgtttgaac tggtaatgat aacccaagtg cacaaactga
     1201 tcatggtatt tctcgtcagt taactctaaa gcgcgctcat aagtcgcctt atttggaata
     1261 atgatcttct tagtacgcac attatcactt tccaaaatca actgcatatt acctggaatg
     1321 gcatcataaa gaggttcctg ccataccaag acatccgagc cagatttatc tggataatga
     1381 aaggaaacca agaaaggagt cgctagagta ttaaagataa gctgactggt gtctatttcc
     1441 aaatcttgca aaaagaaggt gataaattca actttatttg caaagtaacg catggactga
     1501 ccaggcaaag tcaataagat atcacccgtc acatggtttt ccaaaataac ttccttttga
     1561 tctacgtccc gataggaagt cataatagct tgccccaaaa catcataagt ggttttagca
     1621 aagcaagcac caaagcgatt gtagtggtca acctgacgta ctcgaccttc taggtctttc
     1681 cagtctacct gtttaaccaa gcgagcctgc attccatcag cataatgaat gacagccctc
     1741 tcctgcgtca catcttcaat acaagcagac tgattatctc ctaaaatttc ccaaaaatct
     1801 gaaacgggaa cttggttaaa atagagaggt tttccatcct cgtaacctag ataataggta
     1861 aaaggagaaa gcagaccatc aggcagaaaa ccatctgcat cgatgaccac tccaagttga
     1921 gaaagaccag tagcgactag actttcatgt aaatctcgac tttcttgact gtaactatca
     1981 taaagttcaa tcatggagca cctcctctac tgttttcttc cacttttcta aaatttcttt
     2041 ggtcaagaag ccttctgcaa tttggtaaga ataggcacgc atagcttcca aacgattttc
     2101 ttgatacaat tgacaaatct tagcggcata agcttgcttg atttggtctt ctacatggtc
     2161 agatgaactt ggaatcaaat aaccattttg cccatcctct ataaaggtct gattaccata
     2221 aggtacatca aaaccaatta gaggtagacc tgaaccaata gcttccatca aggtcagacc
     2281 aaatccttcg ctggtagaag ccgttaagta gacctcatac tggctataaa tctgcgaaag
     2341 ttccgcatgc cccttgagtt ggatatagtc ctctgcctga tgatttgcaa taatttctct
     2401 aagcagagaa tcttctcctc cactaccata aatatcaaag gttaattcag ggatttcctt
     2461 acgagcctca atcacagcct taaccaacca atcaatgtgt ttttctttgg ccagacgtga
     2521 agcggtaatt aaagaaaatg gcttacgtcc ctgacttgac tccgtcaagg aatcaatact
     2581 acctacagga atggtaacaa tctttggctg atgctgagta tatttggcaa attgctcttg
     2641 tagaacttca ttttgtctat cagtagacac gataaagaag tcaaccttat ctgcattggt
     2701 aaactgatag tcataatagt tattccaaag gatgtagtcc tcatttgtag cattttcact
     2761 ataatgctcc gcatgaacaa ctaccgctaa atgtgctgtc tgtgcttcct caaacacaac
     2821 ctgaccaatg cctgtctccc tatcgagaat gaccaaatca gacttattca aattcaaaga
     2881 tttcataaag gcacgcacaa aagcttgctt tccatagaaa atcttatcct tgaaatgata
     2941 aacttcttcc ttcccttgat tcatcaagat atcatagact ggagtcccgt cttcattgta
     3001 aaaagttcgt tggtataaga ctgcaacatt gtccttggga gcaaaatact cgctacaata
     3061 acgcgtataa gaaaagtaat ccttccgaat caggtttccc ttaaaaacat actcggcatg
     3121 ttgaaccaag tccttgttct catcaaccaa ataacaggtt acaaacttat cttggtcaaa
     3181 aaagaagaca cgtaaaacct tgccattttt ttctctgtga ctttcttcac caccaaagta
     3241 agccaagaca tcatccactg tcacgctagt aggcgcaatt ttgatatctg tgaaatgatt
     3301 ataaagccag ataacctgat tatcatcaaa accaatattg gctgttaagt gctgaatatt
     3361 atcggctaaa atcatatctg taaagataaa cttagaggac agatttaatt tccgaaaaac
     3421 accagcacga taggcttgag cgtattcaac accgctacta gcccaaccaa ttcctaaatt
     3481 tatattgtaa attgtcatat tttctcctct tatggaaaat gagtcacgat ttcacctttt
     3541 ggagtgacct caaccagccc catcaggaga ttacgcacca tatccgcacg gatttgttct
     3601 ttcatagctt caaagcccgc gtaggcttct tgatagtact ctacgattgg atttttctga
     3661 ctagcagatt gaccaccgat agccatggat agctgttgta gatagtctac ctgctctacc
     3721 cagttgtcat caatggcttt aagcagtgaa agtcgtaaaa actgttcata taagtcatgt
     3781 tgattaagta attctttctt ttcagaaagt tctttatcaa tcacctgctt cataaaacta
     3841 cgaactgcag ttttgtcagt tacatctata taatctggaa cctctttaac atgaaaacta
     3901 atattggtca caataaagtg aaacagtaat tcacgactag catagtgatc agccgctacc
     3961 tcttctgtat atctctcaat gatatccaca acaacatcct ctaagtcacg agaaccatct
     4021 attagacgat tacgctcctt gtaaatcata tcccgttgaa tattcatact ttcagcatat
     4081 tctagagtct gacgacgtgc cgaacggcca gcactatcac tggcatgctg agccttttcg
     4141 actagtttcc ggtatttacg acctttcaat acttccggtt gagtcatatc ttgaacctga
     4201 tagtctttgt actttttatg cacccaagat ggaccaaatt tcttgataac atcatcctct
     4261 aaggatacaa aaaatttact cataccagga tctccctgac gaccagaacg gccacgaatt
     4321 tgtaggtcga tccgctgact ttccatccgc tcagtcccaa taacaatcaa gcccccaagc
     4381 tctgcgactc ctttaccaag cttgatatcc gtaccacgtc ctgccataga ggtagccact
     4441 gtcacagccc ccatctgacc tgactcggag ataatctgag cctcacgcgc cgcattatta
     4501 gcatttagga cattatgggc aatcccttca cgaaacaaga gagacgaata gagttgagac
     4561 atttcaactg agcctacaaa aacgagtaag ggatttccct tagcatggta ttgcttgatg
     4621 tactccaagg atgcatacac tttttcaggt aaagtgatat atagattatc tggatagtca
     4681 atccgttgtc tcggacgatt ggttggaatg cgtactacag acatattgta agtttcaata
     4741 aactcttttt ccgcgacctt acctgtccct gtcataccag atatcttatt aaacatctta
     4801 aaaagactct gataggtgat cgaggccata gcccgcgtct caggagataa tttgacatgt
     4861 tccttggctt caatagcctg atggagacct ccttgaagtt tagtcatttc cattagacgc
     4921 cctgttccct tatcaaccag taccatctca tttccacgaa tgatatagtc cttatcttta
     4981 gtaaagagct tatgagctcg aatcgcataa accaaatgac gagcaaaaga cgcatgctct
     5041 tccttgtata aattatcaat ccctaggaaa ttctcagcag acttggcccc cttagtagtg
     5101 agccaaacct cctctttctc ctctttaaag atataatcct ctccttcgac caaggttgtt
     5161 acaagtgtat caatgatcgc atagtaatta gactgaacac gaggagaacc cgcaataatc
     5221 agaggagttt gtgcactatc aagcaagata tcatcaattt catcaataat cacatagtta
     5281 aacggtcgta aaaacttacc ttcttcattc gaggctaggt tatcatttag ataatcaaaa
     5341 cctaaattac tattggttgt gtagatgata tccgaagcat agataagctt cttttcttca
     5401 gctttcattt ccttctttgg atcttccgta aatggtacac caatggtcaa tcctagaaaa
     5461 cgataaactt ggcccatttc ctcggcatca cgctttgata aatactcatt aggagtcaca
     5521 accatcactc cttctcctga aaaagcgttc aaatagacag gcatggtagc tgtcaaggtc
     5581 ttaccgtccc ccgtattcat ctcagcaaca tttccatagt gcatgacaat agctcccatg
     5641 acttgaacat cataggggaa catccctaaa atccgcttat ctgcttcacg caccacagca
     5701 aaagcttcaa ccaaaatatc gtctagactt tctccctcgg aaagacgctg acgaaactct
     5761 actgttttag ctactaattc ttgatccgaa agagaggaca tcttgccttt cagggcatta
     5821 atctgcttta aaatcttttt cactttccta agctggaaat cttgacctaa acgtctaaac
     5881 acttctgatc tccttgatag aaaaatgata aaaagttaag gactcaaatc cagcacttaa
     5941 aagagaaact tgataagtat aactatcttc tggataagta aatatgaaat ctttcgcttt
     6001 ttctaccttt ttttctaaaa tatcaccata gcggtcaaaa aaagttatct tggtataaac
     6061 tccattttca ggctgacaat caaaaaccag tgatagttga tactcctgct ttctttttaa
     6121 taagggaagc tgaggttggg ttcgtgcagc ctggtaattg acactagaaa accaagtctt
     6181 tagaatctca ccagatggca atagaggatt atacagacga acacttttgt caaggtaata
     6241 agatacagtt gttccataca tataagtccc accaacttct ccccaataaa tagactgtct
     6301 ctgtgtaata atcatctttt ctcccttcca aaaccagtct ctaagaccat tctataaaag
     6361 tgcaaaaacc aagaaatatt ggtatctgta tcatcattgt gtcgtccagc agttccttta
     6421 gataaaatct tcgcacctgt attacacaga taagacacta attgttcata ggcttgtgga
     6481 tccatttctt catctttcat ataggataaa ccaaaggttg tctttgaaaa atttgcttgt
     6541 ttaaaaattt tccaaaaacg ctgatccaac tccgtcatat cttgagaact tgtcccacct
     6601 gtatgatgaa ttaaacaatc aaaagctaag ttagagacac ccggtgcgtc caaacgtcca
     6661 cgactagcta tagttcctaa attagccaag ggcttaccaa ctatgatggc atggggttca
     6721 aaagaagcac cataatagag agccggaaac gttcccatag aaagacctga taaaatcaaa
     6781 tccttatgat caaagcctaa ataatcaaga tagtgagtga tcgtatcctt tacttttccc
     6841 tctagctcat ccgttccgag ataaaaagct cccccctcta aacgtggatc agaaaataaa
     6901 atgaagggac atccaagagt tttcatcata aagtaaccct cgaatccttc tgcaggtcga
     6961 taacctgcaa aatagacagt caaaggcggt ttaaaatcac ctggatggaa gaaatagttt
     7021 atttcatcac gcttggaatc atgtaggata tttccaccaa gtacaaactt accaaattgt
     7081 tttcgactcc atcgttggtg aagattacct agtttgatag ttccacgacc tcttgcttca
     7141 acagatatcg agagaaagta gtctccgtct cgactatcca taaaaagtgc ttgctccaag
     7201 tctttttcag atactattac ttcttcaaag aaatcatcaa cagacccact ccacatttta
     7261 cggattacta aacgaaagtc acaattgcct tccttctcat attcaagcca caactcaata
     7321 gggagtgttt tttgcaccat aatattataa gcccaatagg caagctgggc aaaatcttgc
     7381 ccaaactcac cttccaaact gacataatcc aatccttgat aagaaatagc tcctgtaaaa
     7441 tttggattga cttgtatcgt cggaggaaag agtttatcac catacccacc gccaaaaaga
     7501 gatttactta aatcattgat tagttgttgg ggacttaaaa aatcaattgc ttgtgcacat
     7561 cgttttttta gaaaatccac aacctctcta tcatttattt gtagattctg gttataaaat
     7621 aaagtataag gttcaaaata ttttacatag gaaaataagt ctttagcata ctgaccatct
     7681 tctattaaaa ctgcatgaaa acggttaata tcctcttttt caattatttc acgaagagct
     7741 tctgatgagt ttgggtaaaa ataataccaa ctcatatttt caggtatgtc atagtgattt
     7801 tcccaattgg caagtcctat ctgtaaaata ttaagttcct ttgacatttt taacctcctc
     7861 tatccatttc tctaattttc caagaaattg ttgtcctgtg tgctccttaa tcttatcaat
     7921 tgaatatatc aaggactcat tccactcctt caacctatct gtgtaataat gtgcagcctt
     7981 agaaaattct gtaacatctg ctaacaaata accatttttt aaatgttcaa catagacggt
     8041 ttcaactagg ttgatttgag gaattcctgc actaatccca gcaatctgtg tgtagagatg
     8101 aggatgtcta tttaaatcca caatcaaacg gacaaattct agtgttttta tcaaatctaa
     8161 ctcatcattc aagttaacaa actgtaagcg taagtcctgg tgttgatttt cttccagagg
     8221 attttctgca tcaccataat caatcgcctt tcccagattt tcggattgaa tgttttcttg
     8281 gatgaaagac tcaacaatcc cttcaacctc attcatttgc tcctgactag cagcaaaggc
     8341 tccaaaaatc acctcagtat ccttattttc agcgacaaag gacaagactt gaagcagagc
     8401 ttgattatca atcccctgct caaaatccag ttgaaaataa atgatggatt ctttcttagt
     8461 ttggcttcgt cccaatcgta atcgggtgtc aaaagatgat aaatgataac attgatgcat
     8521 tcgttcagga tacaactcct gcaacaatcg taaactatcc tctctatcca ccaaaatcaa
     8581 atccgatttt tcaaaagtta catctaaatc cctaaaggta tcttgagaat tacgtccaat
     8641 gaacagactc aacagtttag gattagtact aggtaaacga tctagtacca actggtcatg
     8701 atgagaatga gaaggaagca taaaaatatc ctgatccttc acatacgttt gcagataatt
     8761 ctcaaaaaat tctgccacca aatctcccat attttgatag gtaagcattt taaagcgata
     8821 acccaaaatt ggattgactt ctacctgtcc tccttctttt aaacgctctc taaattgcca
     8881 aactccctta ggattcaaat attcttgata ggctgcttgc ccatcttcaa aaaaaataat
     8941 actcgatata aaccctcgat catccatgat atggtgcata tgtatttgac cattcggtcc
     9001 aaaatactgt atatcactga tgaaaccttc aactccatgt tcaaccttag caaatttctt
     9061 cccatttttt tgaacgataa tcgtaaaggg actataaata aattcacagt catcatccca
     9121 ctcaatatct ctaatgctta aaacttgggt atggagatta tgaaaatctt gcataacatc
     9181 aaaaacggaa taagtatccg tttctaacac accatgtcta tataaaaaat aacgtagatg
     9241 aggctggtaa gctaatacta atagacgaga atctatatct tgctcttgaa agagccgaat
     9301 ctggtgaaag gtatcatcaa actctagacg aaaatgagaa aaataccatg gagtgatatc
     9361 tgcatgccat gttctttctg acccatacca agctggaata aaataataca taaaagtctc
     9421 ctaaatcaaa ggtctatagg tctcatttag ccttaaagcc ttgacctcgt ctctaatcgt
     9481 aaaaatcatg cccccgaaca tcataaataa gcctggaatc attgccaatc gtaataactt
     9541 ttcatcaaac aaaacaaaaa gcatgggacc acctgccata atcacattaa agagaccacc
     9601 tatgactgag aaacgaagga ccaatcgatt aataaatcga ctagtatccg cacctggata
     9661 aataccataa atgtattctc cagatttttt catacggtct gcaatctctt ctccattcat
     9721 cgtaacaaaa gcaaaaatga tactaaataa aaataagacc gaaatataaa catagaccca
     9781 caaaggcttc ccaaccataa attcctttga taaagccgct agccctgaat gattagggaa
     9841 aataaatccc aacaagatga acaaataagc tggtacacta agaaaactca tcacatacat
     9901 ataaggcatc ccacctgcag gattcaacat gatttcgaga taagaatagc gtttaaatcg
     9961 attgtgtaag ccaattttat taacaggaac caaatagcga gctcgataca taagggcaag
    10021 caagtaagaa aatataatgg tcataaaaac aagcaagaca acaatccctg tagggatata
    10081 aaccagttta aaagtttcaa taacatcctg agggatattt aaaacaatgc tggataggag
    10141 gattacaata gaacccccaa ttcccatgct cgcatttaaa tctgacaacc aaacaagaaa
    10201 aaacgttcct gctatgagta acaaggtatt cattagagca accaaaatta ccgagtagga
    10261 ggattgtact ggcaagctca agctaactgc caaggattga atcacagcaa ttagcaaggt
    10321 cagatacatt cttcgacgat cttgaatttc aatcgctgta gaacttagcc ccaatttttt
    10381 agaatatgaa aacatctgcc acaaaatcat agctgacatc caaggggata atccaacaga
    10441 aaaaattgac aaacttctta gatttccacc tgttagggcg gctgagaagg ctagataggc
    10501 tgttgaacct cctaaaaaat ctttagtatt taggtcaaca aaagggagag taatacgact
    10561 tcccaataca tagataaaca gtagaaataa ggtaaatagt ccttttttta ctgctattga
    10621 cgaataaatc ttagtcataa aacactcccc tcaccttcat tgtttgtgat atggtaaata
    10681 acaattcttt tatttcaact tttaccattt ctttgttctg catcaaaaaa caactttaat
    10741 ctgaaacaaa tatctttata ttcctcagta tctgttaatt gatggtattc taaagtttgc
    10801 ttataatctt ttaaaagatt gacaaatcga atacgcagaa cggagacatc caaaccagcc
    10861 aagatacaat ccgatatttt cttagaaaac acttcaacaa tatctcttgc ccaggaaaga
    10921 tcaaattccg ttctcatgat gcttcctgaa cgtcttctat acagatagag attatcgttt
    10981 ataaagacga ttttagaggc taaaagataa aagcgatgca tagttgcttc atcatcaaag
    11041 cggcgaccat ttgaaaagtg aacttcattg aataattctt ttttaatcaa cttaaatgtc
    11101 ggcaatataa aggccgagct attgaatttc caatctcctg cttgacggtt cataatttct
    11161 tgtatagcta attcttcgac gcaaaaatct tgccctgtta cataaaaata aaaattcccg
    11221 tcactttcgt cataattata gtaattccct ataacaacat ccgcatcctt ttcttggact
    11281 tgctgataaa gagtttcaat catattttct tttacgatat catctgaatc aacaatcgtg
    11341 atgtactctc ccttagctac actaatcccc atatttttag cttgtgctgc cccccccctt
    11401 attttcttga tgcaatactc gcacacgatt atcttgcatc ataaaagcat cacaaatttc
    11461 cccagaatta tccgtagaac tgtcatcaac taaaataatt tctatatttt gataggtttg
    11521 cttcagaata tgctcgacac actccactaa atattttccc gtattgtata tcggtaccac
    11581 aacactaatt aattcactca ttactctatc tctatattct tcattctatc cactaaatca
    11641 tctggtctct ccacagaaaa aataccgtca tagagtccat catccatact tttacgtgtg
    11701 atatcaaaag cgaagatttt cttgccactt tcttgtgccc ttgtaactac attaaaaacc
    11761 tctccacctg tatta
//
LOCUS       DAVHSI010000052        11616 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.053, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000052 DAVHSI010000000
VERSION     DAVHSI010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.053"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VVR21_001851"
     CDS             complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VVR21_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU6055653.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2499..3368)
                     /locus_tag="VVR21_001852"
     CDS             complement(2499..3368)
                     /locus_tag="VVR21_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU6055654.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3591..4112)
                     /locus_tag="VVR21_001853"
     CDS             complement(3591..4112)
                     /locus_tag="VVR21_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6055655.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4070..5149)
                     /locus_tag="VVR21_001854"
     CDS             complement(4070..5149)
                     /locus_tag="VVR21_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU6055656.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVIEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVRYVDEQGRLLSLKNNTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPITATVTANYYKEGRQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5260..5514)
                     /locus_tag="VVR21_001855"
     CDS             complement(5260..5514)
                     /locus_tag="VVR21_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055657.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5872..6405)
                     /locus_tag="VVR21_001856"
     CDS             complement(5872..6405)
                     /locus_tag="VVR21_001856"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6055658.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6392..6607)
                     /locus_tag="VVR21_001857"
     CDS             complement(6392..6607)
                     /locus_tag="VVR21_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055659.1"
                     /translation="MGKERREQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(6574..6717)
                     /locus_tag="VVR21_001858"
     CDS             complement(6574..6717)
                     /locus_tag="VVR21_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU6055660.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            6951..8669
                     /locus_tag="VVR21_001859"
     CDS             6951..8669
                     /locus_tag="VVR21_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU6055661.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVEIEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8780..9127
                     /locus_tag="VVR21_001860"
     CDS             8780..9127
                     /locus_tag="VVR21_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU6055662.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9394..10227)
                     /locus_tag="VVR21_001861"
     CDS             complement(9394..10227)
                     /locus_tag="VVR21_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6055663.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDITLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     G"
     gene            complement(10240..10869)
                     /locus_tag="VVR21_001862"
     CDS             complement(10240..10869)
                     /locus_tag="VVR21_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU6055664.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(10879..11520)
                     /locus_tag="VVR21_001863"
     CDS             complement(10879..11520)
                     /locus_tag="VVR21_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU6055665.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
BASE COUNT         3421 a         2442 c         2104 g         3649 t
ORIGIN      
        1 actattgtat aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa
       61 accgcgtcag cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac
      121 ctaaaaacag tgttttgagc agtctgcagc taactttcta taacaaaatg aaataagaac
      181 aagacaaatc aatcaagaca atcaaatcga tttctaacaa tgttttagaa gtagatgtgt
      241 actattctag tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa
      301 tatctaaaaa aagaaccttg ccaagcaaga ttcttttagt gtctgactta aataattgtt
      361 cttctgggaa ctaaatcgaa ttaagcttcg atttctgtaa ccatacctga accaacagta
      421 cgtccaccct cacggataga gaatgtagta ccttgttcta cggcgattgg gtgaatcaac
      481 tcaacgtcga ttgtcacgtt atcaccaggc attaccattt cagtacctgc tggaagttcg
      541 attgaacctg taacgtcagt agtacggaag tagaattgtg gacggtagtt gttgaagaat
      601 ggagtgtgac gtccaccttc ttctttagta aggatgtaga cttcaccttt gaatttagtg
      661 tgtgggttga ttgaacctgg tttagcgata acttgtccac gttcgatttc atcacgttga
      721 acaccacgaa gaaggacacc tacgttatct ccagcaagac cttcgtcaag ttgtttacgg
      781 aacatttcaa caccagtaac aactgctttt tgagtttctt ctttgatacc aacgatttcg
      841 atttcgtcgt tgactttaac gataccacgg tcgatacgtc ctgaagcaac tgtaccacgt
      901 ccagtgattg agaatacgtc ctcgactgga agaagcaatg gtttgtcagt gtcacgttct
      961 ggttctggga tatactcatc aactgtgttc atcaattcca taacgatgtc ttcgtattta
     1021 gagtcacctt caagagcttt aagtgctgaa ccttggataa ctggaagatc gtcacctggg
     1081 aagtcgtatt ctgacaatag gtcacggatt tccatttcaa ccaattcaag caattcttcg
     1141 tcgtcaacca agtcaacttt gttcatgaag acgataaggt gtttaacacc aacctgacgt
     1201 gaaagaagga tgtgctcacg agtttgtggc attggtccgt cagttgaagc tactacaagg
     1261 atagctccgt ccatttgagc agcaccagtg atcatgtttt taacgtagtc cgcgtgtcct
     1321 ggagcgtcga tgtgagcgta gtgacgtttt tcagtttcgt actcaacgtg cgcagtgttg
     1381 atagtgatac cgcgttcgcg ttcttctgga gcagcatcga tagacgcata gtctttaggt
     1441 tggttaactg atgaaggcaa gcgacgtgcc aaaacagttg tgatagctgc agttagggta
     1501 gttttaccgt ggtcaacgtg tccgatagta ccaatgttaa cgtgtggttt actacgatcg
     1561 tatttttctt ttgccatttg agtaaaagcc tccaataaaa tatattttat agatagacag
     1621 taggcaatac agtctaactt tccttactat tttatcaaat ttcagctaaa ttgcaagtgt
     1681 tttacaacgt ttttgtgaat tattcttggt aaaaatttaa ctaattaata gaaagtacta
     1741 aatagactta tccttcaagg agttttcagc attatccatc cactcacttg ctgaaaatgt
     1801 aaacagtctc tggtttatat agtaaaatga aacaagaata gggcaaatcg atcaggacag
     1861 tcaaatcgat ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
     1921 tatacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcttagt ttgccctttg
     1981 attttcattg agtataaaat tgcagataaa acgataacaa tcataggact cagcagagtc
     2041 aatgtaggtc gaagaatagc ccccctaatc gcttatttta tagcaaaatg aaatagaaac
     2101 tgaacatttt gttgaggaag gtaaatcaat tcctcacaat gtttgagaaa gaagggagga
     2161 ctattccaac ttcaacccac tataaagcag acttacaaga tagggaaccc atctccgata
     2221 atattccgat aatatatagt agaatgaaaa ctgcacaatt tgattggaga attcaaacca
     2281 atttctaaca atgttttaga aacaagggtc tattatttca actgcaacct actatagccc
     2341 attgaagctg gaatagccca ctgagacttc taaaccactg ctggagagga gtttgtttag
     2401 agtttctttc atttccctaa aaaatcaaaa agagagaacc agtctgatcc tctcttactt
     2461 atagatggtg ctcactcaaa tgttaaagga gctatttctt agagataaag gaatttgaat
     2521 acagctactg ccgcaattgc tgctgcgata ggtgctacta ctggtaccca agaataccac
     2581 cattttgaat cgcctttatg ctcaccaaga actgattttg gaaggaaagc atgaaggaga
     2641 cgtggtccca agtcacgggc tgggttcaag gcaggtcctg taggtcctcc aagtgatgtt
     2701 accaaagcca taacgaggaa tccaagtgcc aagtgagcca cagaaagtcc tgaagcagtg
     2761 tgtggagcca cctgtgcttt aatagccaag tcagaaaaat caactgtttg tcctgcttct
     2821 attgcctttt gtttcatgaa ttgaagcact tcagcaccaa agaagttttt agtcaaacca
     2881 agagctgcaa agaacaaaac aaatgaacca acaaactcat taatcaaacc attgacagtt
     2941 gctgcatagc gactttcttt tgtaccatgg tcaatacttg aaatagttga gaaagttccc
     3001 aagatgttat ttggtttttc agttttcaag tagaatggac ggtatgttgc cacaactaag
     3061 gcttggccaa agatagcccc caagacttgc gcgataatgt aaggtaccac ttgtgcccaa
     3121 gggaaaagac cgctaactgc aagccctaga gtgaaagcag ggttgatgtg attcccagat
     3181 acgttaccaa acatcaaggc tgggatcata acccccatac cataaccaac agcgatgacg
     3241 atccagccac tttggtgacc tttcgtacct ttaagttcaa cgttggcaac tgcaccattc
     3301 ccaagaatga tcaaaatggc agttcccaaa aattcagtgg catacttcag tgcccatgtg
     3361 aaatccattt gctagattct ccttaaaatt ttttagatat tccttatttt atcaattttt
     3421 accctattta gcaactgatt tctggaaata tttttaaaaa aataggattc atagtttccc
     3481 agttcaacgt acttgtaagc gtttttattc ttcacgaaag acctcattct caaaaccagg
     3541 aaaaagccca catctatgag cttttcctgg ttcctagatt ctaaaatcta ttatttttca
     3601 tcttcttttt tcttgaagaa tcctaatcct agaccagcta acaaggtcat gataccagca
     3661 ctagccaagg tagcattagc ttctgtacct gtgtttggca attcctctct cttacctgtc
     3721 tcataagtcg gaacttctgg gtctggattc actggagttt cagtttttgg agtacctggt
     3781 tctggagttg gtttatctgg tgttgataaa cggtcatacc ttaccgttat ttctttatca
     3841 ctagagtctg acgtaacttc ttgtgattca actgttggaa tatctggatc tttgtacttg
     3901 tcaatcttac cagatataac ctcgtcccag tttcctgttg tccattcacc gtaggttaca
     3961 actcccgtga ccttgttctc agtttttgta cggcttaagg ttacaggttg aacaacatct
     4021 tcttttacat tttggttcgt aactttatca acgtaatgaa tgatacgcgt tatagtcttc
     4081 gtctcagtag aggttgctgt tttgggaacc actgtttcct caacattctc acggtagtaa
     4141 tagtcaactg ttgcaccgtc ttctggtacg catttgcagg agttgctacc aaggtgtatg
     4201 ttgttttcct tgtgataact cggtcttctt tgtcctcagt tgttgttttc ccttcaatag
     4261 tttttgattc tgtggtatac tcagaaccta tcgctaaatc agcttttata acagactctg
     4321 ccaacttctc ttgcctacct tctttatagt aattggctgt tactgtagca gtgattggcg
     4381 cttcgctttc tctataaact aaggtcactg ttctaccttc gcttacaata ttcccagtta
     4441 aacttgcaga atttgtatct gcttctttaa aagtataata ttttccgtca gtagtagtca
     4501 tgctactgag ttttttatct gtgacattat agctggtacc aatcagttgt tttttattgg
     4561 taatgtaggt tccgtcactt tctttttctc caattccagt attatttttc aatgatagca
     4621 aacgcccttg ttcatcaaca tagcgaactt tcacattttc tgagattagt tctgccaatt
     4681 ctgaggtttt tttctttttc tcttcttcgg gaatatttag ttttggaatg attttttcaa
     4741 taacggttcg tgatggttcc acagtatctt ggatgactga aaagtcagct agaattggga
     4801 gattatactg aacacggtga ctttgagtgt ttactcctac tctttcatta ttctctgaaa
     4861 atacttgtac ggtataagaa acaacatctt ttcctaatag aacatcccca gtagagaaat
     4921 agccgccttt tcctagtttg ctatctccag agcccacttc tttcctaatc ttatcagata
     4981 gttttttacc agtcagtaca ttcgttcgca caatcccttt gtctacccct acaaagtggg
     5041 agaatttttt gaactcttca gaaccagatc tagcccaacc attattaagg gcatttgctt
     5101 ttgtatttgt attctctctc aaaggtttgg cgattagaat tatattcatc ggcgcttaga
     5161 gttgctgcta tatctgactc ttgaatacca acttccttac taccatttct agcggcagta
     5221 tatgtgtatt tatctgtttc tacttctagc tgattatcct taacatgata ggtaattttc
     5281 tcctggtata agagtcttca gtagtttata tgctctgtca tcatctttag ctttagaagc
     5341 agctgagttt agccaagttg gggtattagg agtatcttta tcagcctgtt tcaagacatt
     5401 attcaagtca tttgctagcc tattggttat cctcactgtg aaagttttct tccagtctga
     5461 accactttta ttagacttag atatgctcat gaaatcctgg tcaacattca acacaatatc
     5521 gccttgtttt ttagcatctt ccgttgcttc tgcttcaaat tgatcatgga gtttttgttg
     5581 ctctggtgta tagttttttt atttacacga tttaatgtac tattttttat tttagtatta
     5641 agaactccat taatacgatt tttaaattct gcttcaaaaa atcccttaat ttgttggtgc
     5701 gcaagttcaa cattcaaacc tttcttatac aagtcttcat tctgatacaa gtcttcattc
     5761 tgaacgattt cggctacacg gtgaatggtt tgattgtata ccgtcttctc ttaaccagca
     5821 gtatccttag ttttaatgac tactcgatag gttcctttag aaccgttata gtcatctagt
     5881 tttaaaaaag cattccaaac attcaaaaat agttggaact tcccttaata aatccgtcac
     5941 tttctttttc aagatagccc aagcttgctc aataggattc aaatccggtg aataaggtgg
     6001 tagaggtaag aaaaagtgtt tatcttggat gcagagttca tccaaaatgt tcttgggatg
     6061 aaaactagca ttgcccatga caataacatg aggtgtcttc aaagcaggta ggagttgcgt
     6121 tttgaaccac tccacaaaga aatcgcttgt catgcttttc ttgtaaatca tgggagctat
     6181 aaactctccg tctacttgtc ctgcaacaat tgaagttcgc tcaaaacgac gtccgctaat
     6241 cttttcatag actttctccc ctctaggagc ccctgcataa ggacgataga ggtagcggtc
     6301 gattcctgtt tcgtcaatat atacgattgg taaatctttt aggttatcca aaatatcaag
     6361 aaactcagcg actttctctg gctcttgttc cttaaagctc gtcatctttt tttaaagtga
     6421 ccttaatctg ctttaaagct gcccatactg aaggaacagc acaatcaaaa tgtgccgcaa
     6481 tttcccgtaa aaaagcatct ggatgagcct ctacaaaggc tttcaattcc tctaaaggaa
     6541 tctttcggtt tttgacgact cgctttttcc tctctatgtg tccttgttca cgtctttctt
     6601 ttcccacgtg aagagagttc tgacgccaac accaaaaaac ttggctgcct cgacatgact
     6661 gtgcccctct ttgatggaat ctaatgctcg ctgtttaaaa tcagtactat atgccatagc
     6721 tttattataa catgtatttt ataaactaag ctactatatc aatgttttgt tatgagaaga
     6781 cttacttttt ttactgaaat tgaatttttc ctagcctcaa catcatataa ccccaaaatt
     6841 caatctgacc tggtttgaag agatgttcga agcagataag gttttactaa aactaaaaaa
     6901 aatgatataa tcaaactgat taaatgtttt aaaactaaag gagaatttga atgtcttacc
     6961 aagaaaatta ccagaaatgg gttgattttg tggagcttcc tgactacctt cgtcaagatt
     7021 tggaaaatat ggacgaaaaa actaaggaag atgccttcta tacaaatctt gaatttggta
     7081 ctgcaggtat gcgtggcttg gttggtgctg gtacaaaccg tatcaacatc tacgttgttc
     7141 gccaagctac tgaaggattg gctcgtttga ttgagtcaaa aggtggaaac gagaaagaac
     7201 gcggtgtagc aattgcctac gatagccgtc acttctcacc tgagtttgcc tttgaatctg
     7261 cggcagttct tgctaaacac ggcatcaaat cttacgtatt tgaaagcctt cgtccgactc
     7321 cagaactatc atttgcagtt cgtcatctca actgtttcgc aggtatcatg gtcacagcca
     7381 gccacaaccc tgctccattt aacggttaca aggtttacgg tgaagacggt ggacaaatgc
     7441 ctccacacga tgcggacgct ttgactactt atatccgtgc aatcgaaaac ccatttgcag
     7501 ttgaagttgc tgatgtggaa attgaaaaag cttctggctt gattgaagtt atcggcgaag
     7561 ctgttgacat agaatacctt aaagaggtta aggacataaa catcaaccca gccttgattg
     7621 aagaatttgg taaagacatg aagattgtct acacaccact tcatggtact ggtgaaatgt
     7681 tggctcgtcg tgctcttgcc caagcaggat ttgactctgt tcaagttgtt gaagcgcaag
     7741 caactgctga cccagacttc tcaactgtaa catctccaaa cccagaaagc caagcagcct
     7801 ttgcccttgc tgaagaactt ggtcgtcaag ttggtgcaga tgttcttgtc gcaactgacc
     7861 cagacgctga ccgtgttggt gttgaagttc ttcaaaaaga tggtagctac ctcaaccttt
     7921 caggtaacca aatcggtgct atcatggcta aatacatctt ggaagctcac aaaaacgctg
     7981 gaactcttcc tgaaaatgcc gctctctgca aatctatcgt ttcaactgac ttggtaacga
     8041 agattgctga aagctacggc gcaactatgt tcaacgtctt gacaggtttc aaatttatcg
     8101 ctgaaaaaat ccaagaattc gaagaaaaac acaaccacac ttacatgatg ggatttgaag
     8161 aaagcttcgg ttacttgatt aaaccatttg tacgtgataa agatgccatc caagccgttc
     8221 ttgtcgttgc tgaacttgct gcctactacc gttctcgtgg tttgacactt gctgacggta
     8281 tcgaagaaat ctataaagaa tatggctact acgcagaaaa aacaatctct gttactcttt
     8341 caggtgtcga tggtgctgaa caaatcaaag cgattatggc taaattccgc aacaatgctc
     8401 caacagaatg gaacgcaaca gctatcactg tcgtagaaga cttcaaggca caaactgcta
     8461 ctgttgctga cggtactgtt acaaacttga caactcctcc aagtgatgtg ttgaaataca
     8521 cacttgctga cggttcatgg attgccgttc gcccttcagg tacagaacca aaaatcaagt
     8581 tctacattgc agttgtaggg gaaaccaacg aagaatcaca agctaagatt gctaacatcg
     8641 aagcagaaat caatgcattt gtaaaataaa gacctataaa agatgagacc aaccaacctc
     8701 atcttttttc gtatcaaatc taagcaattt tagaaacttt atggcatact agacttatca
     8761 atgaaagcga ggtaatctca tggaacaatt tttagataac atcaaagacc ttgaagtcac
     8821 tacagttgtg cgtgcgcaag aagctcttga taaaaaagaa actgcaacct tctttatcgg
     8881 tcgcaaaact tgcccttact gccgtaaatt tgcaggtaca ttgtcaggtg tcgtagctga
     8941 aaccaaagct cacatttact tcatcaatag tgaagaacca agccaactca atgatttgca
     9001 agcattccgc tcacgctatg gaatcccaac tgtaccaggt tttgttcata ttacagatgg
     9061 acaaatcaac gtccgttgcg actcttcaat gtcagcacaa gaaatcaaag atttcgcagg
     9121 attgtaaaaa atcagctaac aagtcttaaa atcacaaaaa cgcataatgt aaggtgcaaa
     9181 aaccttgata ttatgcgttt tattgttcct aaaacagtta catcagtatt tcattacaga
     9241 acattttaat tttggaagtc aaatcaattt ttaacaatgt tttagaaatc acagtgggct
     9301 attccatatt caatcgctat tatcgttttc ctagattaca aaaaaactac gttttgctaa
     9361 tcaaaacgca gtttcagcca ctattttatc ttactatcct tcttttactt ctttggttgc
     9421 tacatcttct ccaaaccatt tttggctgat ttcttggaac ttgccgtcct tgtaaagact
     9481 agaaaaagct tcatttatct tcttaaccaa ggttatatct tccttacggg ctccaaccgc
     9541 aaaagcttct gtttctagtc caactgtaaa gacattataa tcgtttaaaa caccttctgc
     9601 ttctaaataa tagtttgcat agacacggtc aatcaataga ccatcaattc gatcgttttt
     9661 caaatcaatc aaggcttcat taaaggtttg gtattgattc gcttccttat tagcgacaat
     9721 attcttcaaa atttctggat ttgcttcaaa gtccgcataa ccagatgaac cagcttgagc
     9781 tcctaatgtc tttccagtca tatcctttgc agtcgtgata ccagatgatt tcttcgtaac
     9841 caatacctgc tcattcttca tatatgagtt actgaaagca accttttcac ggcgttcgtc
     9901 tgtagcggaa tagccattcc aaatcagatc aatcgttcct tttgtcaatt cagcttcttt
     9961 caaatcccaa tcaatcggtt gccaatttac cgtgattccg tatttttcaa aaacagctgt
    10021 agctaaatca atatcaaatc ctgcataaga accatctttc tgagcaaatc ccattggaac
    10081 aaaagtacta tcaaatccaa tagtaataga cttgttagac tggtactttg accaattatc
    10141 tccactagtt tcgctagaat ttttcccaca agctactaag aacaaagcag tcatcagact
    10201 gactaataca agcatccatt ttttcatcca tttttcctcc tatttaggtt ctactttcaa
    10261 taatacatct gcgatatttt cagcaaactg caaatcatgg gtaaccacaa tctgggtcat
    10321 cccaagttcc ctattttgca agattagctt ctccacttcc aaacgtaatt ctggatccag
    10381 ggcagaagtt ggttcatcgt agccaatgat ttctgggtca atcatcatag cacgcgccaa
    10441 agccacccgc tgcttttgcc caccagatag tgagaaagga taggcctctg cgtgtcctcc
    10501 tagtcctaac tgttccaaga gtccactcgc cttcttctca gcctcttcct gcttcattcc
    10561 catggtcttc acaggcgata aggtcaaatt gtccagaact gataaatgag ggaacagttg
    10621 aaaatcttgg aatacaaatc ccagtagatt gcgcttctgc aattcatcca gctctaaagg
    10681 ttgtccatta taaaagattt gccctgaatc aatggtttca agacctgcaa gcatacgtaa
    10741 aagagttgtc ttacctccac cagaaggtcc aacgatagcc aggatttgct tttcaggaat
    10801 acttagactg aaattagaca ggatttgttt gtctccaaag actttattga tatttcgtaa
    10861 ttctaacatg gcagcctcct atctataata actatacttc ttctcaactt ttttggaaat
    10921 aattgtcaca atcccaatca aaatcaaata aatggctcct gccaagaaca taggaactag
    10981 actagcatcg cggttagcag ctgttcgact agccaagata aggtctgaaa ttccgagagc
    11041 atagaccaaa gaagtatcct tgaccaaact cataacttca ttaaagacac taggaagaac
    11101 gatcttggtc acttggggca agataatata gcgcactctg tcaaaagggc taaacttcaa
    11161 gaccttggcg gcctcatact gtcctcttgg aatagtgtca attcccccac ggaaaatttc
    11221 tgcaaagtaa gctgcatagt tgagaacaaa ggcaataata gctgcaggaa ggcggtctaa
    11281 acgaatccca atacttggga gcacataata gataaaaatc agttgcaaga gtaagggggt
    11341 tcctcgcata acccagatgt aaatattaat cagataatgg aggggcttcc aatggacttg
    11401 caaggcaaag gcaatcaaaa cgcccaaagg aatcgaaaat agcaagacca gtgcaaagac
    11461 ctgtacagtc gtgctcgcac cattcagtaa actcggtaat atctcaaata aataagacat
    11521 actgcacctc ctaaaagtaa ttgttcctat tatagcatga ataaacaaga ttaccaagta
    11581 tttttgtaaa aagattctac catatacaaa taaaaa
//
LOCUS       DAVHSI010000053        11097 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.054, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000053 DAVHSI010000000
VERSION     DAVHSI010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.054"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            392..1264
                     /locus_tag="VVR21_001864"
     CDS             392..1264
                     /locus_tag="VVR21_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU6055666.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            1277..1441
                     /locus_tag="VVR21_001865"
     CDS             1277..1441
                     /locus_tag="VVR21_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055667.1"
                     /translation="MTVILGFLFLFLMSWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(1410..1754)
                     /locus_tag="VVR21_001866"
                     /pseudo
     CDS             complement(1410..1754)
                     /locus_tag="VVR21_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1897..2208
                     /locus_tag="VVR21_001867"
     CDS             1897..2208
                     /locus_tag="VVR21_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055668.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            2212..2820
                     /locus_tag="VVR21_001868"
     CDS             2212..2820
                     /locus_tag="VVR21_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU6055669.1"
                     /translation="MKKYFISGLGSNAYHSEEESICLIGHSLGGDLARYLASEFEEVK
                     KLILLDGGYLDLDKILPLDTELEETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKA
                     VRQSYHWNVEYNRYELAINYENIEAILRLRRKIQAFKREVGDTLFISPRYPNEATWRE
                     EALKELPDYFDTIFLENFGHELYTQAPKEIASLMNEWLAYFL"
     gene            complement(2950..3765)
                     /locus_tag="VVR21_001869"
     CDS             complement(2950..3765)
                     /locus_tag="VVR21_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU6055670.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(3762..4667)
                     /locus_tag="VVR21_001870"
     CDS             complement(3762..4667)
                     /locus_tag="VVR21_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU6055671.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            5057..6373
                     /locus_tag="VVR21_001871"
     CDS             5057..6373
                     /locus_tag="VVR21_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEU6055672.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIINENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFADLVDGVFYFYPWGD
                     NWLTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQFDINNLIWRLYIH
                     SKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLENYDIERAKKQYIQ
                     ELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTIISNNCVGGLIYKQ
                     LGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWTHEVYPLGHLGDI
                     DIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNKMDNLPYSNKLIL
                     VNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL"
     gene            6475..8604
                     /locus_tag="VVR21_001872"
     CDS             6475..8604
                     /locus_tag="VVR21_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU6055673.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            8591..9040
                     /locus_tag="VVR21_001873"
     CDS             8591..9040
                     /locus_tag="VVR21_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU6055674.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            9099..9371
                     /locus_tag="VVR21_001874"
     CDS             9099..9371
                     /locus_tag="VVR21_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU6055675.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9725..9916)
                     /locus_tag="VVR21_001875"
     CDS             complement(9725..9916)
                     /locus_tag="VVR21_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055676.1"
                     /translation="MKHKEHILIGFLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10344..>11097
                     /locus_tag="VVR21_001876"
     CDS             10344..>11097
                     /locus_tag="VVR21_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055677.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEV"
BASE COUNT         3588 a         1912 c         2260 g         3337 t
ORIGIN      
        1 tgattgagtt tggaatagta cgctgtagct gctaaaacat ttctaggaat taatttgcct
       61 ttcctaatag agttgttcat atcttatttc aatctattat gtttttcacc tctaacaatc
      121 gcaatctctt ctttatctat gaatgaaatc gatttctatt tttgtaagta aagcataaca
      181 cgaaatccac gaaaatgaaa acctttgttg tgttttcgta aaaaatttgt tgacagagca
      241 cggaacgcct actataatta aatcaagctt aaggaaataa caaaaaaaca aatcggaggg
      301 aaagacgatg aacacattaa atgagaaagt aatcaatatc tgtaaagcag tagttaaaga
      361 aactttaatc caagacattt aggagaaaga aatgaagaaa tcaagaaaat tagccacatt
      421 aggaatctgt tcagctttgt ttttaggatt ggctgcttgt caacaacaac atgctacttc
      481 tgaggggacg aatcaaaggc aaagcagttc agcgaaagtt ccatggaaag cttcatacac
      541 caacctaaac aaccaggtaa gtacagaaga ggtcaaatct ctcttatcag ctcacttgga
      601 tccaaatagt gttgatgcat tttttaatct cgttaatgac tataatacca ttgtcggctc
      661 aactggctta tcaggagatt tcacttcctt tactcacacc gaatacgatg ttgagaaaat
      721 cagtcatctc tggaatcaaa agaagggcga ttttgttgga accaactgcc gtatcaatag
      781 ttattgtctt ttgaaaaatt cagtcaccat tccaaagctt gaaaagaatg accagttgct
      841 tttcctagat aatgatgcga ttgataaagg aaaggtcttt gattcacaag ataaggaaga
      901 gtttgatatt ctattttcga gagttccaac tgaggcaact acagatgtca aggttcacgc
      961 tgaaaagatg gaaacattct tctcacaatt tcaattcaat gaaaaagctc gaatgctgtc
     1021 tgtagtcttg cacgacaatc tggatggcga gtatctgttt gtaggtcacg ttggggtctt
     1081 agtacctgct gatgacggtt tcttatttgt agagaaattg actttcgaag aaccctacca
     1141 agcgattaaa tttgctagta aggaagattg ctacaagtat ttgggcacca agtatgcgga
     1201 ttatacaggc gagggactgg ctaagccttt tatcatggat aatgataagt gggttaaact
     1261 ttaatagtgt tatgatatga cagtaatctt aggattttta tttctatttt tgatgagttg
     1321 gtgggttatt tcaatcgtta atagccagaa accactcaaa aatgaaacat ttattggcta
     1381 tgtccaaaga tacgatattg atgggaatgg ctatcaatca ttaccgtgtc ctcagaactg
     1441 agaggagttc ttgaaatcgt aacaccactt tgaacaagag ttacttcaac ccattggctc
     1501 cgacggagta agttgctttc gtgaacacca aaatcagccg caatttcttc ataagtgcgg
     1561 tattctcaca catattgaag agtggccata agaaggtctt ctaggcttaa tttaggtttt
     1621 cgtccacctt ttgcgtgttt aagttgataa gctgttttta atacagctaa catctcttca
     1681 aaagtggtac gctgaacacc aacaagacgc ttaaatcgtg catcagttag ttgtttactt
     1741 gcttcataat tcatagaact actataccat attttgtttc gcaggaagtc taatgctaaa
     1801 atcttatcag tgagaagatt tcttaaagtt tattctttgt agtttcatct gtattagtac
     1861 ataatttaac ttagagaaaa taggaggact aatcgaatgg aattaaaaga ttttacagaa
     1921 aaagaacagg aaatgattaa gaaaaggctt acaatgtcta atattagtga caaagaaact
     1981 actgagaaga ttctggcgct agtaccacaa gacttgatta agcgaatccc gttttttgtc
     2041 agaaaacatg ctacaacacg tacgattaaa cgcatttcaa ttgaataccc tgaactctac
     2101 gctgtagctc aaacaagtgg tgagattcca gaaaaagaac gcgaagaatt gcgtcagatt
     2161 atcacaacta tctttgaaca aaagatgaat aagcatagta ttaagtagag aatgaaaaaa
     2221 tattttatta gcggtttggg aagcaatgcc tatcatagcg aggaagaatc tatctgtctg
     2281 ataggccatt ctcttggagg agatttagct cgttatctcg catcggaatt cgaagaagta
     2341 aaaaaactga ttcttttgga tggtggctat ctagatttag ataagatttt acctttggat
     2401 acagagttag aggaaactaa aaattatatc aaatctcaaa ttgttttgga cttagatgtt
     2461 cttacttcta aagaaaaatc tgaagcaaag cattggtcag aaaatatgga gaaagctgta
     2521 agacagtctt atcactggaa tgttgagtat aatagatatg agttggctat aaattatgaa
     2581 aatatagaag cgatactccg cctacggaga aaaatacaag cttttaagag agaagtggga
     2641 gataccttgt ttattagtcc tcgctatcct aatgaagcta catggagaga ggaagcccta
     2701 aaagaattgc cagactattt tgatactatt tttttagaaa actttggcca tgagctttat
     2761 actcaagcac ctaaagaaat cgctagtcta atgaatgagt ggctcgctta ttttctatga
     2821 gctacttgta ttgctggaaa tggtataaga tgaaaatcta caagtcacta attttcatat
     2881 aacaaaaaaa cgaacaggct ctttttctgt tattcagaag agaacttgtt cgtttttatc
     2941 ttgattttct taaaaagctc tatatacata gggattttct ggtttatcga ctttggtaaa
     3001 gctgtcgatt tccaaggttg gaaggttttg tttgagttct ttatggtagt gattgaccag
     3061 ttttcctttg gctgttatcc aagtgttgtt ttcatactgc cgggtattgc ccttggtcag
     3121 caatccatag acaccagaat ctgcgataca gtggataatg ccgaatcgga acagaaattg
     3181 actattggca tgactggggt cgttatagac aaagcctgta aactggattg tcttgccctc
     3241 aaattcatct ggatagtcgt agatagcctc catgacttcc atatagtttt cattagtgat
     3301 ctgaatacta tcttgggata agtatttatc cgccgccgtt cgcatttcct tttcataggc
     3361 tgattttgaa aaataagaac tggtatctgg tttcaaatat tggcttgtcg tcccttcgct
     3421 tgtctgaatg gctagatccg ttccttccga tagggggaaa tgataacctt tagcagaaac
     3481 ggtctgagaa tccaagctaa cagttgggaa agttaagccg atgacaagtg gaatagccag
     3541 aagagaaata ctcgtcatct tggccaatcg gctgttcaga tgactgtggg ttttgacttg
     3601 cttcatccag atatacaatt gaacaattgc caagataaag gaaagcacca tggaaatata
     3661 ggccagatag gaatagtgca tgttgatgta ctggtttagt ttgcccgaca gatggaggta
     3721 aatagtcagt tcaaaatagc cagctaaaac taaaaatcga atcataggat gactccaatc
     3781 aagagagaat aggctaaaac gaccagagtc acaatcgtaa tgaagtgact aataaatcgt
     3841 gctttcaagt aatttttcat catgagaata tttttgatat ccagcattgg gccaatgacg
     3901 agaaaggcca gaactggagc caaaccgaaa ctcgagagta gagaagcacc tataaaggca
     3961 tccgcctcac tacagagcga aagaagaaag gccaaaagca tcaagagcag gatggcaaaa
     4021 agaggagtcg cactgataga ggtcagaatc cgagtcggaa cgtagacctg tattatagaa
     4081 gcaaagaggc agccaaatac caaataacgc cccgtatcaa aaaattcatc aatggcctgc
     4141 acaaagactt gaaaaacttt ttttgcagaa ctcaagtaag aaaaatcatg ctcatgacaa
     4201 gccagacgat tttctttctg aatcggttct tgccagaaaa atcctagaaa aattcctagt
     4261 attacagcca caagaatgga acccagagct cgtaataggg cgacatggaa ggagttgcca
     4321 aaggcagaat aggtcgcaaa aagaacaatg ggattgataa caggtgctgt cacaagaaaa
     4381 ggaactgccg tgtaacttgg aacctttttt tccagaaaac gattgatgat ggggacgatt
     4441 ccacattcac aagaagggaa aagtataccg acaaaggtcc caaaaaagat tctcccccaa
     4501 cgatttcgag ggagaaaatg ataaaccttg tcaggtgtga tataaacttc aatcagccct
     4561 gagacaatgc ttcctatcag aacgaaggga agggcttcaa tgataatgga gagaaaaatg
     4621 gctccagttt gaagtacact agatgggagt tgttgaaaag cagtcatcta gtttttcttt
     4681 tctgctttga cttttttctc tttgtcatca gggaaagtaa cttgtttcaa atcagggagt
     4741 ttagcaaact cttcaaacat cttgtccaag tcgtctcgtt ttgtaaattt gacagccata
     4801 ggtgtacctc gattctaaat tctacctcta ttatactatt attttgcgga aaagggaaaa
     4861 gttaaaattt caaattgagt agctaagaga taatatagct tgatattacc tgatatatat
     4921 cataattgtg ctataattaa ataaaaagaa aatcattatc agaaaattat gggaggtagt
     4981 caaactgact tactcaatta gtgttgtttt gttacatcaa ggagataaaa atagtttatt
     5041 agagtctttg tcaatagtgg agagacaaac attaaaagat atagaagtta ttattgtaaa
     5101 tcaatctaca gaggagatag cttccattag ccaacagatg aatctatcat ttaatattaa
     5161 gattataaat gagaattctt ttgctgagtt gtctgatatg attacaggag attatattac
     5221 gtttctatct tcaaatgatt cattatttga ttggacattt gaaaagatgt atcatgcgat
     5281 aaaattatcc gattctgatg ttgttcttgg tcattttgct gatttggttg atggagtatt
     5341 ttacttttat ccttgggggg ataattggtt gacagaaaat ttaacgaatg ttcaagtttt
     5401 acaaaagatg gatgatacag atcatcgaat tagaaaacaa tatcgctcat tatttggaaa
     5461 attattcaat agtaagcttt tacgaaaaat aaatcaattt gatataaaca accttatttg
     5521 gagactttat attcactcta aaactgcaac ctatattaat ttcccgacat atatctataa
     5581 acctgttata gatgctaaac ctctaaaaga ctcctacaaa atcatattag aaaattatga
     5641 aaatagaatc aaagattgcg ccgtcttaga aaactatgat atagaaagag cgaaaaaaca
     5701 atatattcaa gaattggcaa attttagtgc ttggttaaaa aatgacggtg aatatttaga
     5761 ttctgatatt gtttatcata agttaatagc tgcagagaaa ggaattttcc cttttcttga
     5821 gcttgataga ttagatttta cgattataag taataattgt gttggaggat taatttataa
     5881 acagcttggt tttcaatata gaacaccttt tgttggttta tttattcttc ctgatgatta
     5941 ttataaactt acaaagcatt ttcgttatta tatggaacaa gaacttgttt tcgaagagga
     6001 acttatttca ccgagctgga ctcatgaagt ttatcctttg gggcacttag gagatataga
     6061 tattcatttt ctacattatt ctagtattga agaagcacga actaagtggg aaaaaagaaa
     6121 aaaacgcata aattggaata atctttattt taaatttgat aataaagatt cagctagtga
     6181 agaaatttta aataagatgg ataatcttcc ttattctaat aaattaattt tagtcaatcg
     6241 tccatataaa aatttgaaaa gtcaatgtgt tattccaggt caggaacatc ttccagaact
     6301 ggctattatg tctgatccat taaatacttt tgatatcatg gcttggttaa aaaaaggtgg
     6361 caatgctctt taagtgcaag ttattgcgct gtagcatata aatctatttc ctacatattt
     6421 tttaaatgtt ctacgagtta atttgaaacg tttagcttgt ggtataatag atttatggat
     6481 aaaaaatatg aaaaaatctc tcaggatttg ggagtgatgt taaagcaaat tgataccgtt
     6541 ctaagtttga cagctgaagg ggcgactatt ccctttatcg cgcgttatcg caaggacatg
     6601 actggtagtc tggatgaggt ggcgattaag gctattattg atttggataa aagtctgaca
     6661 aatctcaatg accgtaagga agctgtctta gctaagattc aagaacaagg taagttgacc
     6721 aaggaattgg aagaagctat cttagttgcc gaaaaattag cagacgttga agaactctat
     6781 cttccttata aggaaaagcg tcgtaccaag gcaaccattg cccgtgaagc tggactcttt
     6841 cctcttgctc gtttgatttt gcagaatata gttgacttag agaaagaagc tgaaaagttc
     6901 gtctgtgaag gatttgcgac tggcaaggaa gccttgaccg gtgcagttga tattttggtc
     6961 gaagccttat cggaagatgt gaccttgcgt tctatgactt atcaggaagt gctgagacac
     7021 tctaaactta cttctcaagc caaggatgaa agtcttgatg aaaagcaggt ttttcagatt
     7081 tattatgatt tttcagagac agttggaact atgcaaggct atcgtacctt ggctctcaat
     7141 cgtggggaga aacttggtgt cttgaagatc ggttttgaac atgcgacgga ccgtattctt
     7201 gccttctttg ctactcgttt caaggtgaaa aatgcttata ttgatgaagt tgttcagcaa
     7261 tccgttaaga aaaaggtctt gcctgctatt gagcgtcgta ttcggacaga attaactgag
     7321 aaagctgaag agggagctat ccaacttttt tctgacaatc tgcgcaatct cctcttggtt
     7381 gctccactga aagggcgcgt ggttcttggg tttgacccag cctttcgtac aggtgccaag
     7441 ctagctgtcg tggatgcaac aggaaaaatg ctgacaactc aggttattta tcctgttaaa
     7501 ccagcatcag ctcgtcaaat cgaagaagcc aagaaagatt tagcagattt aattggtcaa
     7561 tacggtgtag agattattgc cattggaaat ggaacggcca gtcgtgaaag tgaagctttt
     7621 gtagcggaag ttctgaaaga tttccctgaa gtcagctatg ttatcgttaa tgaaagtggt
     7681 gcttctgtct attctgccag cgaacttgct cgtcaggagt ttccagactt gaccgttgaa
     7741 aaacgctctg ccatttctat cgcccgtcgt ttgcaagatc ctcttgcgga attggtcaaa
     7801 atcgatccta agtcaattgg tgtcggtcaa taccaacacg atgtcagtca gaagaaacta
     7861 tctgagagtc tggactttgt tgtcgataca gtggttaacc aagttggtgt caatgtcaat
     7921 acagctagcc cagctcttct ttcacacgta gctggactca ataaaaccat ttctgaaaat
     7981 atcgtcaaat accgtgagga agagggaaaa atcacttcac gctcccaaat caagaaagtt
     8041 cctcgtttgg gggccaaggc ttttgaacag gctgctggtt tcctccgtat ccctgaaagt
     8101 agcaatatcc ttgataatac aggagttcac ccagaaaatt acgctgccgt taaggaactc
     8161 ttcaaatgct tggatattaa ggatctgaat gaagaggccc aaagcaaact caagtcgctt
     8221 tcagtcaagg aaatggcgca agagttagac cttggtccag aaactcttaa agatatcatt
     8281 gcagatcttc tcaaaccagg tcgagatttc cgtgattcct ttgatgctcc agttctccgt
     8341 caagatgtcc tagatatcaa ggacttagtg gttggacaaa agctagaagg agtggtgcgt
     8401 aacgttgttg atttcggtgc ttttgttgat atcggaattc atgaggacgg tctcatccat
     8461 atttcccata tgagtcgcaa gtttatcaaa caccctagtc aagtggtggc agttggagat
     8521 ttggtgagcg tttgggttaa gaaaattgat actgaacgtg aaaaagttaa tctgtctctc
     8581 ctagctccaa atgaaactga ctgattacgt caagcaggtt tcactagaag acttcggcag
     8641 accttttatc catcatgtcc agtggaatag gcgtctacgt tcgacaggtg ggcgattttt
     8701 cccaaaagat gggcatttgg attttaatcc caaggtttat caggaactgg ggttggacgt
     8761 ttttaggaaa attgtccgac atgaactctg tcattatcac ctctattttc aagggaaagg
     8821 ctatcaacat aaggatcggg attttaagga actgttgaaa gcagtggatg gattacggtt
     8881 tgtaccatcc ttgcccaata gtaactccaa gccaatcaag ctctatcgtt gccaatcctg
     8941 ccagcaaact tatcagcgta agcgtaggat tgataccaga cgctatcgct gtggactttg
     9001 tcgaggtaaa ttgctactaa taaatcagcc tgaggactga tgaaagccga gcctacccgt
     9061 gatatactat gtctaaccta gcagaaagag gaaatatcat gaacagtaag ttttataaaa
     9121 tgagacgaaa tcgcatgatt tcaggagttt tagcaggtct gtcagacaag tggaactttg
     9181 atgttaccct tgtacgtttt ctgtttgcca tttttacagt cgcaaacttt ggacttgggg
     9241 tgattatcta tatcatccta gcttctatca tgccaaccaa ggaagaaatc gaagcagaaa
     9301 tgtacggaac aggcccacgt aaacgcaaag aagctcaagc cattgacgat aatgaaggct
     9361 ggttttggtg aggttttaca aaagatttgg aatacgcaaa aagctttaaa tcaatagtct
     9421 aaactgcttg atttaaagct tttttacttt tatactcaat aaaaatcaaa gtgcaaacta
     9481 ggaagccagc cgcaggctgt aatttagtcg gcaatgtgaa gttgacatag tttgcacttt
     9541 gatttttgaa tagtattaat aatatttcgt cagcttcatc cacaaactat agtggattgg
     9601 aactagaata gtacacctct acttctaaaa tattgttaga aatcgatttg actgtcctga
     9661 tcgatttgtc ctattcttat ttcattttac tataaaagca gtaatttaaa tgcagttttt
     9721 taatctattt ttgctgctga gacaatacat ttttggaaaa atggtggatg ctgataacaa
     9781 ctgataacca gcaaataaca taagcagtgc cggtaaattc tgtaccgata aagtgtgtgt
     9841 gttcaactaa gagctgaccg atgaatggag agagcagata gagaaatccg atgagtatat
     9901 gttctttgtg tttcattaaa acgcaccttc tttccttata ggttgaacga cttgcaagtg
     9961 ttaaattgaa tggtatgtta tctaggtaac cttactaaaa tgttagttcc cgcttcctcc
    10021 tttttaaagt aagccttttc atacttatat tttacaactt taaaaatagg aaatcaaatc
    10081 attttctaag taattttgct tatatttcac ccaatcttac aaaaatgtaa gattaaagtc
    10141 tcttttgtaa ggttaggtta tggcaagcgg tctttttttg atgtaaacta gactcataaa
    10201 gaacaaagga gtaacatcat gaaacaaatc ttacataaaa aaactagaaa accaagtcac
    10261 aaagaaattg agcgcattca gctgggatgc actatgatgc aagctacatt tcatttgatg
    10321 ggatattaag aaaggagatt ctcatgacac ttttagatgt aaaacacgtt caaaaaattt
    10381 ataaaactcg ttttcagggc aaccaagtag aggccctcaa ggatattcac ttcaccgtag
    10441 aaaagggtga ctacgttgct atcatgggtg agtctggttc tggtaaatcc actctgctca
    10501 atatcctagc tatgctggat aaaccaagtc gtgggcaggt ttacctaaac ggaactgata
    10561 cagcaactat taaaaattca caggcttcta gtttccggcg tgaaaagcta ggatttgtct
    10621 tccaagactt taacttgcta gatactctgt ctgttaagga caatatcttg cttccgcttg
    10681 tcttgtcaag aagacctata acggagatga tgaagaaatt ggtgatgaca gctgaaaatc
    10741 tgggtatcaa ccaattgcaa gagaagtacc cttacgagat ttctggtggt cagaaacagc
    10801 gtgtagcagt agcccgcgcc atcatcacag aacctgaaat tctcctggcg gacgagccaa
    10861 caggagccct tgattccaag tcatctgcag ccttacttga tgtctttaat gaaatcaatg
    10921 agcgtgggca aaccatcctc atggtaaccc actcaacagc agctgctagc agggccaagc
    10981 gtgttctctt tatcaaagac ggcattcttt acaaccaaat ctaccgtgga gagaagacag
    11041 agcgtcagat gttccaagaa atctctgata ccttgactgt catggcaagc gaggtga
//
LOCUS       DAVHSI010000054        10726 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.055, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000054 DAVHSI010000000
VERSION     DAVHSI010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.055"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            336..2264
                     /gene="glgB"
                     /locus_tag="VVR21_001877"
     CDS             336..2264
                     /gene="glgB"
                     /locus_tag="VVR21_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU6055678.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNPKGVENEK"
     gene            2254..3396
                     /locus_tag="VVR21_001878"
     CDS             2254..3396
                     /locus_tag="VVR21_001878"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU6055679.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3386..4525
                     /gene="glgD"
                     /locus_tag="VVR21_001879"
     CDS             3386..4525
                     /gene="glgD"
                     /locus_tag="VVR21_001879"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU6055680.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFDGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4522..5955
                     /gene="glgA"
                     /locus_tag="VVR21_001880"
     CDS             4522..5955
                     /gene="glgA"
                     /locus_tag="VVR21_001880"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU6055681.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            6014..6659
                     /gene="serB"
                     /locus_tag="VVR21_001881"
                     /pseudo
     CDS             6014..6659
                     /gene="serB"
                     /locus_tag="VVR21_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            6668..7783
                     /locus_tag="VVR21_001882"
     CDS             6668..7783
                     /locus_tag="VVR21_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU6055682.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7780..8226)
                     /locus_tag="VVR21_001883"
     CDS             complement(7780..8226)
                     /locus_tag="VVR21_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU6055683.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8390..9694
                     /gene="eno"
                     /locus_tag="VVR21_001884"
     CDS             8390..9694
                     /gene="eno"
                     /locus_tag="VVR21_001884"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU6055684.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9832..10260)
                     /locus_tag="VVR21_001885"
     CDS             complement(9832..10260)
                     /locus_tag="VVR21_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU6055685.1"
                     /translation="MRKHGFISKRYYQVAIPFTRLFCLVSIDYINCLSETTDKNWHKS
                     DRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKT
                     ITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(10178..10369)
                     /locus_tag="VVR21_001886"
                     /pseudo
     CDS             complement(10178..10369)
                     /locus_tag="VVR21_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10469..10726)
                     /locus_tag="VVR21_001887"
                     /pseudo
     CDS             complement(10469..10726)
                     /locus_tag="VVR21_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3219 a         1900 c         2327 g         3280 t
ORIGIN      
        1 aacattgtta gaaatcgatt tgtcctgtta ttatttcatt ttactatata taatacattg
       61 gagttaaaat agtacacttt gatttctaag acattgttag aaattagatt aaagtcctta
      121 atcgatttgc gcatgtttta tttcatttca ctatagtaga aaaagaaagg cgttttcgca
      181 attttttgaa aaaatattga tttacaattg aacgagtaag tgaacttgtt gtagattttc
      241 aaaataatta aagaagtata gtaatttact tgaatcttct ctaaaaaggt agtataacaa
      301 aaacatagaa aacgcttaca ggagaagggg agtatatgga taatagagaa gcattaaaaa
      361 cctttatgac gggtgaaaat ttttatctcc aacattatct aggagcacat agggaagaac
      421 taaatggaga gcatggctat accttccgtg tttgggcacc taatgctcag gctgttcact
      481 tggttggtga ttttaccaac tggattgaaa atcagattcc aatggtaaga aatgattttg
      541 gggtctggga agtctttacc aatatggctc aagaagggca tatttacaaa tatcatgtca
      601 cacgtcaaaa tggtcatcaa ctgatgaaga ttgacccttt tgctgtcagg tatgaggctc
      661 gtccaggaac aggggcaatc ttaacagagc ttcctgagaa gaaatggaag gatggacttt
      721 ggctggcacg aagaaaacgt tggggctttg aagagcgtcc tgtcaatatt tatgaagttc
      781 acgctggatc atggaaaaga aattctgatg gcagtcctta tagttttgcc cagctcaagg
      841 atgaactcat tccttatctc gttgaaatga actatactca tattgagttt atgcccttga
      901 tgtcccatcc tttgggcttg agttgggggt atcagcttat gggttacttc gctttagagc
      961 atgcttatgg ccgaccagag gagtttcaag attttgtcga ggagtgtcat acccataata
     1021 ttggggttat tgtggactgg gtaccaggtc actttaccat caacgatgat gccttagcct
     1081 attatgatgg gacaccgact tttgaatacc aagaccataa taaggctcat aaccatggtt
     1141 ggggtgccct taattttgac cttggaaaaa atgaagtcca gtccttctta atttcttgca
     1201 ttaagcattg gattgatgtc tatcatttgg atggtattcg tgtggatgct gttagcaaca
     1261 tgctctattt ggactatgat gatgctccat ggacacctaa taaagatggc ggaaatctca
     1321 actatgaagg ttattatttc cttcagcgct tgaatgaggt tattaagtta gaatatccag
     1381 atgtgatgat gattgcagaa gaaagttcgt ctgcgaccaa gattacggga atgaaagaga
     1441 ttggtggtct aggatttgac tacaaatgga acatgggctg gatgaatgat atcctccgtt
     1501 tctacgaaga agatccgatc tatcgtaaat atgactttaa cctggtgact ttcagcttta
     1561 tgtatgtttt caaggagaat tatctcttgc cattctcgca cgatgaagtg gttcatggca
     1621 agaagagtat gatgcataag atgtggggag atcgttacaa tcaatttgca ggcttgcgca
     1681 atctctatac gtaccaaatt tgtcaccctg gtaagaaatt gctcttcatg ggtagcgaat
     1741 acggtcaatt cctagaatgg aaatctgaag aacagttgga atggtctaac ctagaagacc
     1801 caatgaatgc taagatgaag tatttcgctt ctcagctaaa ccagttttac aaagatcatc
     1861 gctgtctgtg ggaaattgat accagctatg atggtattga aatcattgat gcggataatc
     1921 gagaccagag tgttctttcc tttattcgta agggtaaaaa gggagaaatg ttagtctgta
     1981 tctttaatat ggtacctgtt gagcggaaag attttacaat cggactaccc gttgcaggaa
     2041 tttacgaaga agtatggaat actgagttgg aagagtgggg aggcgtttgg aaagaacata
     2101 atcaaactgt tcaaacgcaa gaaggactat ggaaagatta tgagcagacc ttaaccttta
     2161 ccctaccggc tatgggagca agtgtatgga aaatcaaacg tcgcttgaaa tctactaaaa
     2221 ccgtcacaaa taaaaaccca aaaggagtag aaaatgaaaa atgaaatgtt agctttgatt
     2281 cttgctggtg ggcaaggaac tcgtctcggt aaactcactc aaagcatcgc aaaaccagct
     2341 gtgcaatttg gtgggcgcta ccgtatcatt gactttgcac tatcaaactg tgccaactca
     2401 gggattcata atgttggggt cgttacacag tatcaaccac ttgctctcaa caaccatatt
     2461 gggaatggtt caagctgggg actagacggt attaattcag gtgtctctat tcttcaacct
     2521 tattctgcaa gtgaaggaaa tcgttggttt gaggggacta gtcacgctat ttaccaaaat
     2581 atcgactata tcgacagtgt caatcctgag tatgtcttga ttttgtctgg ggatcacatc
     2641 tacaaaatgg actatgatga tatgctccag tctcataagg ataataatgc cagcttgaca
     2701 gtagcagttt tagacgtccc tcttaaagaa gcaagccgtt ttggtatcat gaacacagat
     2761 gctaacaatc gtattgttga atttgaagaa aaaccagctc aacctaaatc tacaaaagct
     2821 tctatgggaa tctacatttt tgattggcaa cgccttcgta atatgttagt cgctgctgaa
     2881 aagagcaagg ttggcatgtc agactttggt aaaaatgtca ttccaaatta ccttgagtca
     2941 ggtgaaagtg tttatgctta cgaatttagt ggttattgga aagatgttgg tactattgag
     3001 tcactttggg aagcgaacat ggagtatatt tctccagaaa atgccttgga tagtcgtaac
     3061 cgtcaatgga agatttactc aagaaacttg atttcaccac caaacttcct cggggcaaat
     3121 gctcatgtgg aagactcatt agttgtagac ggatgtttcg ttgatggaac tgttaaacat
     3181 tctatccttt caacaggcgc gcaagttcgc gaaggagcgg aagtccttga ttcagttatc
     3241 atgagtggag ctatcattgg tcaaggagct aagattaaac gtgccattat tggtgaaggt
     3301 gcgattattt ctgacggtgt cgaaattgat ggaacagatg aagtacaagt tgtaggatat
     3361 aatgaagtag tgggggtagc aacagatgaa gattgataaa tattctgcca ttttaggaaa
     3421 tacagttggt tttcacgata tgtcgacatt gacggaccac cgtccagtag caagtttgcc
     3481 atttgatggg aaatatcgtt tgattgactt cccactttca agccttgcta atgcaggtgt
     3541 tcgtagtgtc tttggtattt tccagcagga taatatcagc tcagtctttg accatattcg
     3601 ttcagggcgc gagtggggct tatcaaccct tcttagccat tactatctag gaatttacaa
     3661 tacccgtgta gaaagtagta cagttggaaa agaatactac caacagcttc ttacttattt
     3721 gaaacgttct ggctcaaacc aaacggttgc cctcaactgc gatgttctta ttaacattga
     3781 tttgaaccaa gttttccacc tacatagtac aacaaaagag cctatcactg tagtttataa
     3841 aaaactagct aagaaagata tttcagaagt aaatgcaatc ttggatgtag atgaaacaga
     3901 ccatgttctt tctcataaac tctttgatag caagtcaaca gctgaaacgt tcaatatgtc
     3961 tacagatatc tttgtcgttg atacaccttg gttgattgaa cacttggaag aagaagctaa
     4021 aaaagaacat ccagagaaat tgcgctatgt tttacgggat ttggctgtaa aagagggagc
     4081 tttcgcctac gagtacacgg gctatctagc caatattcac tctgttaaat cttattatca
     4141 agcgaatatc gatatgcttg aatcacaaaa attctattct cttttctcac caaaccaaaa
     4201 gatttataca aaggtcaaaa acgaagagcc aacttactat gctaatacat ctaaggtaag
     4261 cacttctcag tttgcctctg gtagtattat tgaaggtcaa gtagctaatt ctgttctatc
     4321 acgtaatatt catgtccata aggatagctt ggttaaagat agcctgctct tccctcgtgt
     4381 tgttattgga gaaggggctc aggtcgaata tgctatcttg gacaaagggg ttgaagttga
     4441 gcctggtgtt gtgattcgag gaactgcaga acatccagtt gtggttaaga aaggtgctaa
     4501 agtaacagag gatattcatt catgaaaatt ttatttgtag cagcagaggg tgcacccttt
     4561 tcaaaaacag gtggtttggg agacgtcatt ggcgctcttc caaaatcact ggtaaaagct
     4621 gggcacgaag ttgcagtgat tttaccctac tatgatatgg tagaggctaa atttggaagt
     4681 cagattgaag atgtgcttca ttttgaggtg agcgttggtt ggcgcagaca gtattgtgga
     4741 attaagaaaa cagtattaaa tggtgtaacc ttctacttta ttgacaatca atattatttc
     4801 ttccgtggtc atgtttacgg tgattttgat gacggagaac gctttgcctt tttccaactg
     4861 gctgccattg aggctatgga aaggattgac tttattcctg atcttctcca tgttcatgac
     4921 taccatacag ctatgattcc tttcttgttg aaggaaaaat accgttggat tcaagcctat
     4981 gaggacattg aaacagtttt aaccattcat aatttagaat tccaaggaca attttcagaa
     5041 ggaatgttgg gtgatttgtt tggagttggc tttgaacgtt acgctgatgg cacccttcga
     5101 tggaacaact gtctgaactg gatgaaggca ggtattctct atgcgaaccg tgtttcaacc
     5161 gtttcaccta gctatgctca tgaaattatg actagtcagt ttggatgtaa tttggatcag
     5221 attcttaaaa tggaatctgg taaagtatct ggtatcgtga atgggattga tgctgatctt
     5281 tataatcctc agacggatgc tcttttagac tatcatttca atcaggaaga tttgtctggg
     5341 aaagccaaaa ataaggcaaa attgcaagaa agagttggct tgcctgttag agcagacgtt
     5401 ccactggtgg gaattgtttc tcgtttgaca cgtcaaaaag gttttgatgt ggtggtcgaa
     5461 agtcttcacc atatcttgca agaagatgtt cagattgttc ttttgggaac tggcgatcca
     5521 gcctttgaag gagctttctc atggtttgct cagatttacc cagacaaact atcaacaaat
     5581 atcacttttg atgtcaaact tgctcaggaa atctacgctg cttgtgacct cttcctcatg
     5641 ccaagtcgtt ttgaaccgtg tggcttgtct caaatgatgg ctatgcgtta tggaaccttg
     5701 ccattggtcc atgaagttgg aggcttgcga gatacagttc gcgctttcaa tccaatcgaa
     5761 ggaagcggta ctggctttag ctttgacaat ctatctcctt attggttaaa ttggactttc
     5821 caaacagcat tggacttgta tagaaaccat ccagacattt ggagaaacct acaaaaacaa
     5881 gctatggaga gtgacttctc atgggataca gcctgcaagt cataccttga cttgtaccat
     5941 agtttagtta attaatagat aaaatcgtat gatgacttca tacgattttt aggctgttta
     6001 gagaggagaa ctgatgtctc aagtaaaagg cttgtgtgtt ttggatgtag atggaacctt
     6061 aatcctagaa gaagtgattg atcttttagg gagagaggca ggtcatgagg cggaaatttc
     6121 gcagattaca agtcgagcaa tgcgaggaga gttggtcttt gaaagcagtt taagaaaaag
     6181 agtgtccttg ttggaaggtc ttcctatttt ggtctttgat aacgtcttca actcaattca
     6241 tctatcgcta aatgtcccag agttcatctc tattctccaa aaaaatggca tcctagttgg
     6301 tctggtgcct ggtggattta caccaatagt tggagagatt agcaaaatcc cttggtattg
     6361 cctatttcac tgccaaccag cttgaagtca aagaaggtct tttaacagga aaattagttg
     6421 gacaaattat aagtccccag gtcaaaaaag aaactctgga aaaatggaga aagaaactaa
     6481 aactttctaa agaaagaacg gtggcaatcg gtgatggggt caataatcta ttaatgttga
     6541 agtcggcgga gttaggaatc gccttttgtt ccaaagaaat gctcaaaaaa gaaataccac
     6601 atcatgttga caagagggat tttttagaag ttcttccttt gattgactgt ttagaatgag
     6661 ggaaaatatg aagattgtaa ttgcaccgga ttcgtttaag gaaagcttga cagctcaaca
     6721 ggtagctgaa gcaataaaaa gaggcttcca acaatcgata gcagatgtag aatgtctcct
     6781 ctgccctgtt ggtgatgggg gagaaggtac tgtagatgct atccgacatt ctcttgacct
     6841 aaaagaaaaa tggatccaag tgacagaccc ttttggacaa aaagaagcca tgcgctattt
     6901 tcaaaaaggg gaactggcac tatttgaagt agctgacttg gttggtcttg gaaaaattcc
     6961 gctagagaaa cgaaacccac ttcaaatcca aacttgtggt attggagagt tgattctcca
     7021 tctcatttct aaagggatta aagatattta tatcggtgtt ggtggcacgg ccagtaatga
     7081 tggaggactg gggattgctg ctggtttagg ttatcaattt tatgataggg atggaaatgt
     7141 cttgcctgct tccggtcaat ccttattaaa cttagcttct gtttcaacag aaaattgcta
     7201 taaaattcct gaaggtgttc aaattcatat tttagcagat gtcgtgagtc ccttatgtgg
     7261 tcatcaaggt gcgacttaca cttttggcaa tcaaaaaggt ctacatccga ctatgtttgc
     7321 agtcgtagat caggcgatcc aagattttta tgaaaaattc tcacctgcaa cattagaaat
     7381 taaaggagca ggagcaggtg gaggccttgc tggtggtttg tgtgcctttg ctcaggcaag
     7441 tatcgtgtct ggaattgata cctgcttgga cttaatcaac tttgataaga aagtttcaga
     7501 tgctgacttg gttgttgttg gagaaggaag acttgatagt caaagctttg ctgggaaagc
     7561 gcctataggt gttgcaaaaa gaacccctgt tggagttcct gttattgcta tttgcggtag
     7621 tcttgctgaa gatttacctc ccctaccatt tgaaaatatc caagctgtct tttctatttt
     7681 ggagaaaagt gaacctttag aagatagttt gaaaaatgcc agtctctatc tggagcgcac
     7741 ggctgccaat attgggcact tattaaatat gtgcaagatt tagctaaacc atttcttcca
     7801 taaggatgtt ttggctggtt cttccttttt aacttcccaa agttttggaa aagcaagtcg
     7861 aaggtctttt tcttctactt gaactggtgc attgctatga ataaccaggc caaaaggaga
     7921 agtaatatgc tcttcagata ctatggtggc ttgactatca gtttcttttg cttcttttaa
     7981 gtagaaaact tgcttatcaa attcgatagt tggtgaaatc ttcacaaata gtggctctgc
     8041 tttttcctga aggttttcta aaataaataa aaagcctttt tctaactgag ggctatttgc
     8101 tgtgtcaata tctacatatc caagaactct ttcctcaaaa gtaccaagat agcgtctttg
     8161 ctcatccgga tttattttta acccaccatg agctttttca agtaattgtt ttgataaatc
     8221 tgtcatgaaa acagtatatc ataaaagtta gaataaaaca gacaaaagaa agcgattact
     8281 ttataaagtt aaggaaaagt tgcacaaaga taacgttttt tcttgaaaaa ggaggggttt
     8341 taaggtatta tagaggtgta aaaaatttaa ctcataagga gagtaaaaaa tgtcaattat
     8401 tactgatgtt tacgctcgcg aagtcctaga ctcacgcggt aacccaacac ttgaagtaga
     8461 agtttacact gaatcaggtg ctttcggacg tggtatggtt ccatcaggag cttctactgg
     8521 tgaacacgaa gcagttgaac ttcgcgacgg tgacaaatct cgttacggtg gtcttggtac
     8581 acaaaaagct gttgacaacg taaacaacat cattgctgaa gctatcattg gctacgatgt
     8641 acgtgatcaa caagctattg accgtgctat gatcgcactt gacggtactc ctaacaaagg
     8701 taaattgggt gcgaatgcaa tcctcggtgt gtctatcgct gtagctcgtg ctgctgctga
     8761 ctaccttgaa atcccacttt acagctacct tggtggattc aacactaaag ttcttccaac
     8821 tccaatgatg aacatcatca acggtggttc tcactctgac gctccaatcg ctttccaaga
     8881 gttcatgatc ttgccagttg gtgcgccaac atttaaagaa gcccttcgtt acggtgctga
     8941 aatcttccac gctcttaaga aaatccttaa atcacgtggt ttggaaactg ccgtaggtga
     9001 cgaaggtgga ttcgctcctc gtttcgaagg aactgaagat ggtgttgaaa ctatccttgc
     9061 tgcgattgaa gctgctggat atgtaccagg taaagacgta tttatcggat ttgactgtgc
     9121 ttcatcagaa ttctacgata aagaacgtaa agtttacgac tacactaaat ttgaaggtga
     9181 aggtgctgct gttcgcacat ctgcagaaca aatcgactac cttgaagaat tggttaacaa
     9241 atacccaatc atcactattg aagatggtat ggatgaaaac gactgggatg gttggaaagc
     9301 tcttactgaa cgtcttggta agaaagtaca acttgttggt gacgacttct tcgtaacaaa
     9361 cactgactac cttgcacgtg gtatccaaga aggtgctgct aactcaatcc ttatcaaagt
     9421 taaccaaatc ggtactctta ctgaaacttt tgaagctatc gaaatggcta aagaagctgg
     9481 ttacactgct gttgtatcac accgttcagg tgaaactgaa gattcaacaa tcgctgatat
     9541 cgcagttgca actaacgcag gacaaatcaa gactggttca ctttcacgta cagaccgtat
     9601 cgctaaatac aaccaattgc ttcgtatcga agaccaactt ggtgaagtag cagaataccg
     9661 tggattgaaa tcattctaca accttaaaaa ataaaatagt tcagtgaact attttatccc
     9721 gaaccatgaa attcaaaagt tcggccgttg atttaacaac gtttctagcc cctcggattt
     9781 tatccgaagg gctatttttg tatttagagg acaaaaaagg gacaaaactt tttaaaaaat
     9841 ctttttcata actttatcca gtacattgat tgcttcatct ttcatattct ttgtgacgtg
     9901 ggtgtagatg gaagtagtga cttcagagtc ggaatgacca actctgtccg tgattgtttt
     9961 taaaggaatt ttattttctg ataagatgct aatagtggtg tgtctgaaga tgtgagggga
    10021 cagatgtttg ggaattggtt ttttaaggcg ttcgtttgct cgctggagag acttgctcaa
    10081 gatagaacta tgaactggtt ttcctgtatt ggtaacaaaa atacggtcgc ttttgtgcca
    10141 attcttatcg gttgtttcgc ttagacaatt tatatagtca attgaaacaa gacaaaagag
    10201 cctcgtaaaa ggtattgcaa cttggtaata cctttttgat atgaacccat gttttctcaa
    10261 taggattgta ctcaggtgaa tagggaggaa gaggtaaaag tttatgccca aactcttcac
    10321 acaagagttc tagcttcctc attctatgga atcttgcatt atccataata tagtagattg
    10381 aaactaaaat agtacacctc tacttctaaa acattgttag aattcaattt tactgtcctg
    10441 atcgatttgt cctattctta tttcatttta ctataataac cgatggtgtg tttaatgttg
    10501 gtaagagaaa cttctgaaac caagcttcaa aaaagtcgct cgtcatcgtc tcttcgtaag
    10561 tcattggagc gattaactca ccattcattt gttagacctg caaccaaaga aattctctga
    10621 tatcttcttc cagatacttt gcctcttctt aactgacctt ttaatgagcg accatattct
    10681 cgataaaaat aagtatcgaa tcctgtttcg tcaatctaaa caggtg
//
LOCUS       DAVHSI010000055        10722 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.056, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000055 DAVHSI010000000
VERSION     DAVHSI010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10722
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.056"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            168..665
                     /locus_tag="VVR21_001888"
     CDS             168..665
                     /locus_tag="VVR21_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU6055686.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            665..2320
                     /gene="dnaX"
                     /locus_tag="VVR21_001889"
     CDS             665..2320
                     /gene="dnaX"
                     /locus_tag="VVR21_001889"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU6055687.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2348..2542
                     /locus_tag="VVR21_001890"
     CDS             2348..2542
                     /locus_tag="VVR21_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU6055688.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2692..3462
                     /gene="sufC"
                     /locus_tag="VVR21_001891"
     CDS             2692..3462
                     /gene="sufC"
                     /locus_tag="VVR21_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU6055689.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3490..4752
                     /gene="sufD"
                     /locus_tag="VVR21_001892"
     CDS             3490..4752
                     /gene="sufD"
                     /locus_tag="VVR21_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU6055690.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4763..5989
                     /locus_tag="VVR21_001893"
     CDS             4763..5989
                     /locus_tag="VVR21_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU6055691.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQNLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5976..6416
                     /locus_tag="VVR21_001894"
     CDS             5976..6416
                     /locus_tag="VVR21_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU6055692.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6470..7882
                     /gene="sufB"
                     /locus_tag="VVR21_001895"
     CDS             6470..7882
                     /gene="sufB"
                     /locus_tag="VVR21_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU6055693.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8081..9322)
                     /locus_tag="VVR21_001896"
     CDS             complement(8081..9322)
                     /locus_tag="VVR21_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU6055694.1"
                     /translation="MKKTFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9425..10534
                     /locus_tag="VVR21_001897"
     CDS             9425..10534
                     /locus_tag="VVR21_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU6055695.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         3170 a         1963 c         2334 g         3255 t
ORIGIN      
        1 gtcgcttttc attataggtc atatgggact ttttttctac acaaaatagg ctccataata
       61 tccatagggg atttacccac tacaaatatt atagagccca aaatcctttg tttactaaac
      121 aagggatttt tcttttgtct ctgctccttt tttgatataa tagttctatg ttaaaatcag
      181 aaaaacaatc acgttatcaa atgttaaatg aagaattgtc cttcctattg gaaggcgaaa
      241 ccaatgtttt ggctaatctt tccaacgcca gtgctctcat aaaatcacgt tttcctaata
      301 ccgtatttgc aggcttttat ttgttcgatg gaaaggaatt ggttttaggc cccttccaag
      361 gaggtgtttc ctgcatccgt attgcactag gcaagggtgt ttgtggtgag gcagctcact
      421 ttcaggaaac tgttattgtt ggagatgtga cgacctatct caactatatt tcttgtgata
      481 gtctagctaa aagtgaaatt gtggtgccga tgatgaagaa tggtcagtta cttggagttc
      541 tggatctgga ttcttcagag attgaggatt acgatgctat ggatcgagat tatttggaac
      601 aatttgtcgc tattttgctt gaaaagacaa catgggactt tacgatgttt gaggaaaaat
      661 cttaatgtat caagcacttt atcgaaaata tagaagtcaa aacttctccc agttagttgg
      721 tcaagaagtt gtggctaaga ctcttaaaca agcggtggag caagagaaaa taagtcacgc
      781 ttatcttttt tctggtcctc gtggaacggg aaaaaccagt gttgctaaaa tctttgccaa
      841 ggctatgaac tgtcccaatc aagtgggtgg cgaaccttgc aataactgct atatttgtca
      901 agcagtgacg gacggtagtt tagaagatgt cattgaaatg gatgcagctt ctaataatgg
      961 ggtagatgaa attcgcgaaa ttcgtgataa atctacctat gcgcctagcc ttgctcgtta
     1021 taaggtttat atcatagatg aggttcacat gctgtctaca ggggctttta atgccctcct
     1081 aaagacgctg gaagaaccaa cacagaatgt agtctttatt ttggccacta ctgaattgca
     1141 caagattcct gctactattc tatcccgtgt gcaacgtttt gagtttaaat caattaagac
     1201 acaggatatt aaggaacata ttcactatat cttagaaaaa gaaaatatca gttctgaacc
     1261 agaggctgtg gaaatcattg ccagacgggc ggaaggtgga atgcgggacg ccttgtctat
     1321 tttggatcaa gccctgagtt tgacacaggg aaatgagctg acgactgcta tctctgaaga
     1381 aattactggc accattagcc tatcagcctt ggatgattat gtggcggcct tgtctcaaca
     1441 ggatgttccc aaagctttgt cttgcttgaa tcttcttttt gacaatggta agagcatgac
     1501 tcgttttgtg accgatcttt tgcactattt aagagacttg ttaattgttc aaacaggggg
     1561 agaaaatact catcatagtt cagtctttgt agaaaatttg gcacttcctc aaaaaaatct
     1621 gtttgaaatg attcgcttag caacagtgag tttagcagat attaagtcta gtttgcagcc
     1681 caagatttat gctgaaatga tgaccgtccg tttggcggaa atcaagcccg aaccagctct
     1741 atcaggagcg gttgaaaatg aaattgctac gctgagacag gaagttgccc gtctcaaaca
     1801 agagctttct aatgtaggtg cggttcctaa acaagttgca ccagctccta gtcgaccagc
     1861 tacgggcaaa acagtctatc gtgtcgatcg caataaagtg caatctatct tacaagaggc
     1921 cgtcgaaaat cctgatttag cacgtcaaaa tctaattcgt ttgcagaatg cctggggaga
     1981 ggtaattgaa agtctaggtg ggccggacaa ggctctgcta gttggttctc aaccggttgc
     2041 tgccaatgaa caccatgcta ttcttgcttt tgagtctaac ttcaatgctg gtcaaactat
     2101 gaaacgagac aatctcaata ccatgtttgg taatatcctc agtcaggcgg caggtttttc
     2161 acctgagatt ttagctattt ccatggagga atggaaagaa gttcgcgcag ccttttcagc
     2221 caaagccaaa tcttctcaaa ctgaaaagga agtagaagaa agcctgattc cagaaggatt
     2281 tgaatttttg gctgataaag tgaaggtaga ggaagactaa agaaagattt catgatacaa
     2341 taagtttatg aataaacaac aatttattat tatggcgctg tttacagctg ctgagaccta
     2401 ttttttcaat gaagcctgga tgactggccg ctatattatg gcagcctttt gggcaatttt
     2461 actctttaga aatttccgag tcagttatgt gatgggcaaa atcgttgatg tcatcgatca
     2521 gcattttaat aggaaagact agccctcagc ttccagacaa aatcaaagcc ttttaggctt
     2581 ttttttgtta tactagaaaa gtatatttat agaatttttg ctctatttct ggggaaatca
     2641 gacgtttttc tagtaagtac tgtaaaagtt ttgaaaaaga aaggaactat catgtcagta
     2701 ttagagatca aagatcttca cgttgagatt gaaggaaaag aaattttaaa aggggttaac
     2761 ctgaccctga aaacaggaga aattgccgct atcatgggac caaatggtac aggtaaatcg
     2821 actctttctg ccgctatcat gggaaatcca aactatgaag taactaaagg tgaagttttg
     2881 tttgatggcg taaacatcct tgagttggaa gtggatgagc gtgcgcgtat gggacttttc
     2941 cttgctatgc aatacccatc agaaatccct ggaattacca atgctgagtt tcttcgtgcc
     3001 gctatgaatg cgggtaaaga agatgatgag aagatttcag ttcgtgagtt tattactaag
     3061 ctagatgaaa aaatggaatt gctcaacatg aaagaagaaa tggcagagcg ttacctcaac
     3121 gaaggcttct ctggtggtga gaaaaaacgc aatgaaattc ttcaactttt gatgttggag
     3181 ccaacatttg ctcttttgga cgagattgac tcaggtcttg atattgacgc tcttaaagtt
     3241 gtgtctaaag gtgtcaatgc catgcgtggt gaaggttttg gtgctatgat catcactcac
     3301 taccaacgtc ttttgaacta tatcacacct gatgtggtac acgtgatgat ggaaggtcgt
     3361 gttgtccttt ctggtggtcc agaattggct gcgcgtttgg aacgtgaagg atacgcaaaa
     3421 ttagctgaag aacttggcta cgactacaag gaagaattgt aatttcctcg tatcttttag
     3481 gagaagtaaa tgactagaga aaatattaaa cttttttcag aaatgcacgc tgaaccaagc
     3541 tggttggctg atctccgtca aaaagctttt gacaagattg agactttgga attaccagtt
     3601 attgagcgtg tcaaattcca ccgttggaat ctgggtgatg gaacgattac agaaaatgag
     3661 ccatcagcaa atgttccaga tttcacagct ttagatcatc acttgaagtt ggtgcaagta
     3721 ggaactcaaa ctgttttcga acaaactcca gttgagttag ctgaacaggg tgttgtcttc
     3781 acagactttc actcagcttt agaagaaatt ccagagctga tcgaagaatt cttcatgtca
     3841 tctgttaagt atgatgatga caagttggcg gcttaccaca cagcttactt taacagtggt
     3901 gctgtactct atattccaga taacgtagaa atcacagagc caattgaagg aattttctac
     3961 caagatagcg atagcaatgt gccgtttaac aagcatatta tgattatcgc tggtaaaaat
     4021 tctaagatta gttatctgga gcgtttagag tcacgcggtg aaggaagtga caaagtaact
     4081 gccaatatca cagtggaagt gattgcacgt tctggtgcgc aagtcaagtt tgctgctatc
     4141 gaccgtctag gtgaaaacgt cactgcctac attagccgtc gtggtaaatt aggcaacgat
     4201 gcaagtattg actgggctat cggtgtcatg aacgaaggaa atgtcgttgc tgattttgat
     4261 agtgacttga ttggtaatgg tagccatgct gacctcaagg ttgtagctct ttcaagtggt
     4321 cgtcaggtac aagggattga tactcgtgta actaactatg gctgcaactc tatcggaaat
     4381 atcctacaac atggggttat ccttgaaaaa gcaactttga ctttcaatgg tatcggccac
     4441 atcatcaagg gtgctaaggg agcagatgcg caacaagaga gccgtgttct catgctttca
     4501 gaccaagcgc gttcagatgc taacccaatt cttttgattg atgaaaatga tgtcactgca
     4561 ggacacgcag cgtctatcgg acaagttgat ccagaagaca tgtattacct catgagtcgt
     4621 ggattggata aggcaactgc agagcgtttg gttgttcgtg gtttccttgg atctgttatc
     4681 gtggagattc cagtcaagga agttcgtgat gaaatgattg caactatcga agagaaattg
     4741 tcaaaacgct aaggggaagc ctatgttaga tgtagaagcg attcgcaagg attttccaat
     4801 tttagatcag attgtcaatg atgaacctct ggtctatctg gacaatgctg cgacgacaca
     4861 aaaaccacta gtagttctga aagctattaa cagttactat gagcaggaca atgccaatgt
     4921 tcaccgtggt gtccatacct tagcggaacg agcgacagct tcttatgaag ctgctcgtga
     4981 aaccattcgt aagtttatta atgcaggctc tacaaaggaa gttctcttta ccagaggaac
     5041 gacaaccagc cttaactggg tggcacgctt tgctgaggaa attctcgctg agggagacca
     5101 ggtcttgatt tcagtaatgg aacaccattc taatatcatt ccatggcagg aagcttgtcg
     5161 aaagactgga gcagagcttg tctatgtcta tcttaaagac ggtgccttgg atatggagga
     5221 tttgcgagct aaattgactg ataaggttaa atttgtttcc ctagctcatg cctccaatgt
     5281 tcttggtgtg gtcaatccga tcaaggaaat cactcaatta gcccaccaag ttggggcaat
     5341 catggtagtg gatggtgctc aatctacacc tcatatgaag attgatgtcc aggacttgga
     5401 tctggacttt ttcgcctttt cgggtcacaa gatggctggt ccgactggta tcggtgtcct
     5461 ttacggcaaa gaaaagtatc ttgagcaaat gtctccagta gaatttggcg gcgagatgat
     5521 tgattttgtc tacgagcaat ctgctagttg gaaggaattg ccttggaaat ttgaggctgg
     5581 aacgccaaat atggcaggag ctattggact tgcgactgca gttgattatc tggaaaagat
     5641 tggtatggat gccgttgaag ctcatgaaca ggaattgatt gcgtacgtct atccaaaact
     5701 gcaggcaatt gagggattga ccatttacgg ttctcagaat ttggctcaac gttcgggtgt
     5761 tattgccttt aacctaggtg atctccatcc tcacgatctt gcgacggctc tggattatga
     5821 aggagtggct gttcgtgctg gtcaccattg tgcgcaaccc ttgcttcagt atttggaagt
     5881 cccagcaaca gctcgtgcaa gtttttatat ctataatacc aaggcagatt gcgacaaact
     5941 agtcgatgcc ctacaaaaga caaaggagtt tttcaatggc actttctaaa ctagatagcc
     6001 tttatatggc agtggtagca gaccattcga aaaatccaca tcaccaaggg aagttagaag
     6061 acgctgagca aatcagtctc aacaatccga cttgtgggga tgtcatcaac ctctctgtca
     6121 agtttgatgc agaggaccgt ttggaagata ttgcttttct aaattcagga tgcacgattt
     6181 caactgcttc tgctagtatg atgacagatg ccgttttagg aaaaaccaaa caagaaattt
     6241 tagaactggc gactattttt tctgaaatgg ttcaagggca aaaagatgag cgtcaagacc
     6301 aacttggaga tgcggcattc ttgtcaggtg ttgccaaatt ccctcaaaga atcaagtgtg
     6361 caaccctagc ttggaatgct cttaagaaaa caattgaaaa tcaagaaaaa cagtaagaca
     6421 agtttctttt gtcttatgaa ttattagaaa tgaagaaaga aaggatatta tggctgaaga
     6481 aagagtagaa ccaaaaccaa ttgaccttgg tgaatataaa tttggtttcc atgacgatgt
     6541 agagcctgtc ttatcgacag gaaaaggact caacgaaggt gttattcgtg aattatctgc
     6601 tgctaagggt gagcctgagt ggatgttgga gttccgcttg aagtcttatg aaaccttcaa
     6661 aaaaatgccc atgcaaactt ggggagcaga cttgtcagag attgactttg atgacttaat
     6721 ctactaccaa aaaccatctg acaaaccagc ccgttcttgg gatgatgtac ctgaaaagat
     6781 taaagaaacc tttgaacgta tcgggattcc agaagctgaa cgtgcttatt tagcaggggc
     6841 ttctgcccag tacgagtcag aagtggttta ccacaacatg aaggaagagt tccaaaaatt
     6901 aggtattatc tttacagata cagattccgc actcaaggaa tacccagact tatttaaaca
     6961 atactttgcg aagttggtac cgccgacaga taacaagttg gcagccctca actcagcagt
     7021 atggtcgggt ggaactttta tctacgtgcc aaaaggtgtc aaggtagata ttccacttca
     7081 aacttatttc cgtatcaata atgaaaatat aggtcagttc gaacgtacct tgattatcgt
     7141 tgatgaggga gcaagcgtcc actacgtaga aggatgtaca gcaccaacat attcaagtaa
     7201 tagcttgcac gctgccattg tagaaatttt tgctttggac ggagcttata tgcgttatac
     7261 aactatccaa aactggtctg ataacgtcta taacttggta acaaagcgtg ctaaggctca
     7321 aaaggatgcc actgttgagt ggattgatgg aaacttgggt gccaaaacga ctatgaaata
     7381 tccatctgtt taccttgatg gagaaggagc gcgtggtacc atgctctcta tcgcctttgc
     7441 taatgcaggg caacaccaag acacgggtgc taagatgatt cacaatgctc cacataccag
     7501 ctcgtctatt gtgtctaaat ccatcgctaa aggtggagga aaggttgact accgtggaca
     7561 agtcaccttt aacaagaact ctaagaaatc tgtttcccac attgaatgtg ataccattat
     7621 catggatgac ttgtcagcat cagatactat tccatttaat gaaattcaca actcgcaagt
     7681 ggctttggaa cacgaagcca aagtatctaa gatttcagaa gagcaattgt attatctcat
     7741 gagccgtgga ttgtcagaat ctgaggcaac tgaaatgatt gtcatgggat ttgtagaacc
     7801 ctttacaaaa gaacttccaa tggaatacgc agttgagctg aaccgcttga ttagctatga
     7861 aatggaggga tcagttggat aaaatttgat tttatactct tcgaaaatct cttcaaacca
     7921 cgtcagcatc gccttactgt atgtatggtt actgacttcg tcagtttcat ctacaacctc
     7981 aaaacagtgt tttgagcaac ctgcggctag cttcctagtt tgttctttga ttttgaagat
     8041 gaacttatat caaaaaatcg cggtttaaaa tcgcgatttt ttataatttc tcgttaacaa
     8101 agcggacaaa ctgattccac caaactttta agaagaaggc tttttcaatt ttcttgtctg
     8161 ctaccatttc gaaactaggg cgctctgtgg tgatgtaacc ttgaccaatc aagtccttgt
     8221 cttcataagt caaatggcca accactgttc cagcttcaag tggtgctggg attgctttgg
     8281 aatcaggtgt gaattgaaca gattgggaag attgattccc aacacgttct attagataga
     8341 tatcctctgg agccactgca gttactgtat cttcttttcc atcttgtaca ggggctttgc
     8401 tatcttgata ggcatcgcct tgttgaacga ttttgcgaag tgtaaatgta gaagaaatat
     8461 aatccattag ggaagatgta gctgtaaatc gagcgtaagg attattgtct tgatgatctg
     8521 catttaaaac aactgtgatg actctcatgc ctttttcgac agtagtacca acaaaagact
     8581 ctccagcctt atctgttgtt cctgttttta gcccatcaaa accaccacgg taagcaggca
     8641 taccttctaa catgtagttg gttgaagtga ttgtcatccc agcaaaagta gaagaaggtt
     8701 ttttggtgat ttctaagact tgtgggtatt ttttgatgag gttgcgagca acgatagcga
     8761 catcataagc actaagctta ttttcctcat cttttttaga acctgggtaa atgttatccc
     8821 ctagagtttc attgttaaga cctgtcgtat tgacaacagt ggcatcctga attccccatt
     8881 ccaagagttt tgcccgcatc atatcgacga aatctttttc tgagccagca attttctcag
     8941 ctagggcaat agcggcgctg ttggcactag ataccagagt tgcttcaagc agctcttcga
     9001 cagtataatt acgggcctcc ataggaatat tactggcttc agaatttgtc gtcaattgat
     9061 aaggataatc agaaatatct acaggagtgg agagggtaat acttccgttt tccaaagctt
     9121 catagaccag ataaacagta atcaattttg ttatggaagc aatttcgaca ggttgcgttg
     9181 catccttctc atagagaatt ttaccagtat ttgcctcaac agcaatcgca tgtttagcgg
     9241 caatggtaaa atcttgagca acagcagtag aagcaccccc taaaagagag acagttaata
     9301 aagttaaaaa tgtttttttc atagtagtct tattctatca taaagaaaaa aaatattctt
     9361 gctttaataa ttcatctgtt aagctttttg aaaatatggt aaaataaagt gagggaggta
     9421 actcatgttt cgtagaaata aattattttt ttggaccaca gaaattttac tcttaaccat
     9481 catcttttac ctatggagac agatgggatc tttgattaac ccttttgtta gcgtgcttaa
     9541 tacaattatg attccatttt tattaggggg ctttctttat tatttgacaa accctattgt
     9601 tactttctta aataaagtct gtaaactcaa tcgtttgctt ggtattttaa ttaccttgtg
     9661 tactttggtc tggggaatgg tcataggtgt tgtctatctc ttacctattt tgattaatca
     9721 gttatctagt ttgattatat ctagtcaaac tatttatagt cgagtacaag acttaatcat
     9781 agacttatct aattatcctg cgctccagaa tttggatgta gaagctacaa ttcagcagtt
     9841 aaacttatcc tatgttgata ttcttcaaaa tatcctaaat agcgtatcaa atagtgtggg
     9901 gagcgtcttg tcagctctta tcagtactgt tttgattttg attatgactc cagttttttt
     9961 ggtttatttc ttattagatg gacataaatt cttgcccatg cttgaaagaa cgattctaaa
    10021 gagggatcgc ttgcatattg caggcttatt aaagaattta aatgcgacga ttgctcgcta
    10081 tattagtgga gtttcgattg acgcaatcat tataggttgt ttagcttata ttggctatag
    10141 tattattggt ttaaaatatg ctttagtttt tgccattttt tctggtgtag ccaatttaat
    10201 tccttatgtg gggccaagta ttggtttgat tcctatgatc atcgcaaata tattcactga
    10261 tccccataga ctgctgattg cagtgattta tatgcttgtt gttcagcagg tagatggcaa
    10321 tatcttatat cctcgaatcg taggaagtgt tatgaaggtt catccaatca cgattttagt
    10381 tttacttttg ttgtcaagca atatctatgg tgtagttgga atgattgtcg cagtgccaac
    10441 ctattctatc ttgaaagaaa tttctaagtt cttatcccgt ttgtatgaaa atcataaaat
    10501 aatgaaagaa cgagaaagag aattagctaa gtaaaagtca ggagaaccct gatttttctt
    10561 tactggaagt ggcctttaga ttagaagact gaaaataagt taaagtctta aactaatttt
    10621 cacagctaag aatagtagaa gttaatctga taaaaatcga aaaaaccagt ggaattccgt
    10681 gtcagggtaa gttccactgg ttttcatagt ctattaaagt tc
//
LOCUS       DAVHSI010000056        10591 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.057, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000056 DAVHSI010000000
VERSION     DAVHSI010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10591
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.057"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            17..460
                     /locus_tag="VVR21_001898"
                     /pseudo
     CDS             17..460
                     /locus_tag="VVR21_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826702.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            498..800
                     /locus_tag="VVR21_001899"
     CDS             498..800
                     /locus_tag="VVR21_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU6055696.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            808..1593
                     /locus_tag="VVR21_001900"
                     /pseudo
     CDS             808..1593
                     /locus_tag="VVR21_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1642..2106
                     /locus_tag="VVR21_001901"
     CDS             1642..2106
                     /locus_tag="VVR21_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU6055697.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPCLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2263..2688
                     /gene="lacA"
                     /locus_tag="VVR21_001902"
     CDS             2263..2688
                     /gene="lacA"
                     /locus_tag="VVR21_001902"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU6055698.1"
                     /translation="MSIVIGADAAGLRLKEVVKNFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2719..3234
                     /gene="lacB"
                     /locus_tag="VVR21_001903"
     CDS             2719..3234
                     /gene="lacB"
                     /locus_tag="VVR21_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU6055699.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3245..4174
                     /locus_tag="VVR21_001904"
     CDS             3245..4174
                     /locus_tag="VVR21_001904"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU6055700.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPTGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            4176..5156
                     /gene="lacD"
                     /locus_tag="VVR21_001905"
     CDS             4176..5156
                     /gene="lacD"
                     /locus_tag="VVR21_001905"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU6055701.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5390..6226
                     /locus_tag="VVR21_001906"
     CDS             5390..6226
                     /locus_tag="VVR21_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU6055702.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLITENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6262..6579
                     /locus_tag="VVR21_001907"
     CDS             6262..6579
                     /locus_tag="VVR21_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU6055703.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEVGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6579..8270
                     /locus_tag="VVR21_001908"
     CDS             6579..8270
                     /locus_tag="VVR21_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU6055704.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8485..9891
                     /gene="lacG"
                     /locus_tag="VVR21_001909"
     CDS             8485..9891
                     /gene="lacG"
                     /locus_tag="VVR21_001909"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU6055705.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9981..10193
                     /locus_tag="VVR21_001910"
     CDS             9981..10193
                     /locus_tag="VVR21_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU6055706.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(10472..>10591)
                     /locus_tag="VVR21_001911"
     CDS             complement(10472..>10591)
                     /locus_tag="VVR21_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HEU6055707.1"
                     /translation="KFDFYTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         3367 a         1893 c         2173 g         3158 t
ORIGIN      
        1 ctttgacaaa aaccttgtgt tttgcttaga agcggataat caagaataac tctttgatca
       61 ggtagcaagc ttgttggaag aacgagaaat tgtcactcct acttatcgtg aagccttgat
      121 cacgcgtgaa aagtcatttc caactggttt agatatggaa tttctaggaa aggacttgcc
      181 aaatgtagcg attcctcaca cagatattgt tcataatcta gctgagaaag tggtggttgt
      241 tcgattagaa aaaccagtaa cttttcacaa tatgatagct cctgataagg aagtagaagt
      301 atccctactc ttctttatca ttaacaattc aagttcaagt caaacaaata ttctggctca
      361 gttgatggac tttttcacag gaaatggaca tcttgaagac ctatcaaaaa tttccgaacc
      421 agaagccctt tatgcttata tagatgaagc aatcgcttaa tcttgtctat taaaaaataa
      481 aatcggagga agtctatatg attaaaattc ttgctgcctg cggtgcaggt gttaactcaa
      541 gtcaccaaat taaaagtgct ctagaagaag aactttcaaa ccgtggttat gatgttcact
      601 gtgatgcagt catggtgaaa gatgtaaacg aagaccttat gaaaggttac gatatcttta
      661 caccaatcgc tgcaacagac cttggttttg aaccaggtat cccagttatc gaagctgggc
      721 caatcttatt ctgtatccca gcaatgagcg ttccagtatt tgacaatatt agacttcctg
      781 cgaaacaaaa tatggtatag tagttctatg aatgatgaag caagtaaaca actaaccaat
      841 gcacaattta agcgtcttgt tggtgttcag cgcacgactt ttgaagagat gttagctgta
      901 ttaaaaacag cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagtcta
      961 gaagaccttc ttatggccac tcttcaatat gtgcgagaat accgcactta tgaagaaatt
     1021 gcggctgttt ttggtattca cgaaagcaac tttatccgtc ggagccaatg ggttgaagta
     1081 actcttgttc aaagtggtgt tacgatttca agaactcctc tcagctctga ggacacggta
     1141 atgattgatg cgacggaagt aaaaatcaat cgccctaaaa aaacaattag cgaatcattc
     1201 tggtaaaaag aaatgccacg ctatgaaggc tcgagcgatt gtcacaagtc aagggagaat
     1261 tgtttctatt gtcatgatat gaagttgttc aaaatgagtc gcagaaatat cggacaagct
     1321 ggtaaaatct tggttgacag tggttatcaa gggctcatga agatatatcc tcaagtacaa
     1381 actccacgta aatccagcaa actcaagtcg ctaatagctg aagataaagc ctataaccat
     1441 gcgctatcta aggaaagaag caaggttgag aacatctttg ccaaagtaaa aacgtttaaa
     1501 atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgagt
     1561 gctggtatta tcaatcatga actaggattc tagttttgca ggaagtctaa taaagaaact
     1621 agcaaggtca ggccttactt tattggtgga catccaggat ttaattgtcc tctacttgat
     1681 gatgaagtct atgaagatta ttatctagag tttgagaaag aagagatttg ctctgttcca
     1741 cgtcctttcc cagaaacagg tatgttggat ttccaagata gaagtccatg tctagaggga
     1801 caaaaagaaa tagatcttag ttatgatctt ttcagcacag atgcagtgac tttggatgaa
     1861 ttgcaatctc gaacaattgc ccttcgttct cttaaacatg ataagggatt gaaagtgcat
     1921 tttgcagaat ttccaaacct catcatctgg tcaactttga acaagggacc tttcattacc
     1981 tttgaaccat ggtctggctt gtcaacatcc cttgaagaag gagatcattt agaagataag
     2041 aagaatgttt gtctcttaga agccaatcag gttgaagaat tagggtttga gatagaagtt
     2101 ttataaaaaa gtaaaaaata aataacaaaa acaaacaaaa gctgttgact tcttcaaaca
     2161 atagtagtat attatgtttg tgaggactaa ttgactgttt tttaaagaca gtcaatacac
     2221 tgctggaatc cagcatagaa aaaataaaaa ggagtataca atatgtctat tgttatcggt
     2281 gcagatgctg caggtttgag attgaaagaa gttgtgaaaa acttcttaga aaaagaaaac
     2341 ttccaccttg tggatgttac agctgaaggt caagactttg ttgatgtgac tctcgctgtt
     2401 gctgcagaag taaacaaaga agaacaaaac cttggtatcg tgattgatgc ttatggagct
     2461 ggtccattta tggttgcaac taagatcaaa ggaatggttg ctgcagaagt atctgacgaa
     2521 cgttcagctt atatgactcg tggccacaac aactcacgta tgatcactat gggtgcacaa
     2581 cttgttggtg atgaattggc taaaaacatc gctaaaggat ttgttaacgg taaatacgat
     2641 ggtggacgtc atcaaatccg ggtcgacatg ttgaacaaaa tgggctaatt agattacagt
     2701 aagaaaggta agttaaaaat gagaattgca attggatgcg accacatcgt aacagatgaa
     2761 aaaatggcgg tttcagaatt tttgaaatca aaaggatatg aagtcattga ctttggtaca
     2821 tatgaccata cacggactca ctacccaatc tttggtaaaa aagtagggga agctgtaact
     2881 agcggccaag ctgatcttgg ggtatgtatc tgtggtactg gtgttggtat caacaacgct
     2941 gtaaataaag ttccaggtgt tcgttctgcc ttggttcgtg atatgacaac agccctttat
     3001 gctaaagaac aattgaacgc taacgttatc ggctttggtg gtaagattac tggtgaattg
     3061 cttatgtgtg atatcatcga agctttcatt catgctgaat acaaaccatc tgaagaaaac
     3121 aagaaattga ttgcgaaaat tgaacacctt gaaagtcaca atgctcaaca aacagacgca
     3181 aacttcttta cagaattcct tgaaaaatgg gatcgcggag aataccacga ctaagaggtg
     3241 acctatgatt ttaacagtca caatgaaccc atccattgat atttcctatc ccttggatga
     3301 gttgaagatt gatactgtca atcgtgtggt ggatgtaacc aaaacggctg gtggtaaggg
     3361 actcaatgtt acccgagtac tttcagaatt tggcgattct gttcttgcta ctggtttagt
     3421 gggtggcaaa cttggtgagt ttttggttga acatatcgat aatcaagtaa agaaagattt
     3481 cttctcaatt cagggagaaa ctcgtaactg tatcgctatt ctccacggag acaaccaaac
     3541 agaagttctt gaaaaaggtc ctgaagtatt ggaacaggaa ggtcaagact ttttggaaca
     3601 tttcaaaaaa ctcttggagt cagttgaagt agtagccatc tcaggtagtc tgccaactgg
     3661 ccttccagtt gattactatg cgagcttggt agaacttgct aatcaagctg gcaagcctgt
     3721 agtcttggac tgctcaggtg cagcacttca ggctgttctt gaatcacccc ataaaccaac
     3781 agtcatcaaa ccaaataatg aagaattgtc tcagcttctt ggaagagaag tttctgagga
     3841 tttggatgaa ttaaaagaag tacttcaaga acctttgttt gcagggattg aatggattat
     3901 cgtttcactt ggtgccaacg gtacttttgc caaacatggt gacactttct acaaggtaga
     3961 tattcctaga attcaggtgg taaatcctgt tggatctgga gactctactg tggcaggaat
     4021 ttcttcagga cttcttcaca aagaatcgga tgcagaatta ctcatcaagg caaatgtcct
     4081 tggtatgctc aatgctcaag aaaaaatgac tggtcatgtc aacatggcca actatcaagc
     4141 tctatatgat caattaatag taaaagaggt ataaaatggc tttaacagaa caaaaacgtg
     4201 tacgcttaga aaaactttct gatgaaaatg gtatcatctc agctcttgca tttgaccaac
     4261 gtggtgcttt gaaacgcctc atggctcaac accaaacaga agaaccaact gtggcccaaa
     4321 tggaagaact taaagtcttg gtagcagatg aattgactaa atacgcttca tctatgcttc
     4381 ttgaccctga gtatggactt ccagcaacta aagctcttga tgaaaaagct ggtcttctcc
     4441 ttgcttatga aaaaacaggt tatgacacaa caagcacaaa acgcttgcca gactgcttgg
     4501 atgtctggtc tgcaaaacgt attaaagaag aaggtgcaga tgcagttaaa ttcttgcttt
     4561 actatgatgt agatagctca gacgaactca atcaagaaaa acaagcctac atcgaacgca
     4621 tcggttctga gtgtgtggct gaagatatcc cattcttcct tgaaatcctt gcttacgatg
     4681 aaaaaattgc ggatgcaggt tctgtagaat acgcgaaagt aaaaccacac aaagttatcg
     4741 gcgctatgaa agtcttttca gacccacgct ttaacattga tgtcttgaaa gttgaagttc
     4801 ctgttaacat taaatatgtt gaaggcttcg ctgaaggtga agtagtttat acacgtgaag
     4861 aagcagcagc cttcttcaaa gcgcaagatg aagcaacgaa cttgccatac atctacttga
     4921 gtgctggtgt atcagctaaa ctcttccaag atactcttgt atttgctcat gaatcaggtg
     4981 caaactttaa cggagttctt tgtggccgtg ctacatgggc aggatcagtt gaagcttaca
     5041 tcaaagatgg tgaagcagca gctcgcgaat ggcttcgcac aactggattt gaaaacattg
     5101 atgagctcaa taaagttctt caaacaacag cgacttcatg gaaagaacgt gtgtaagaaa
     5161 gtcctcctag tttaggaaca tgaatctaaa aaaatttaaa aaaagttgta tgtaaaggtt
     5221 tacaaaataa cttacttgtg ctatacttaa atcacaagtt aatacaaggt gagtgttact
     5281 aagtaatatt aggcatgatc acaggtgaat tagaaatcag ctgattttct agttcatttg
     5341 tggtcatttt ttgtactcat atacctttaa gatataaaag gaggttgaca tgtatcgaat
     5401 tctaaatcca atgaatcaca atgtctcgct tgtcagaaat gataagggag aagaggtgat
     5461 tgtaattggt aaggggattg cattcggaaa gaagaagggg gatttgatta ctgaaaatca
     5521 ggttgagaaa atctttcgga tgaagaccga agagtccaga gaaaacttta tggctcttct
     5581 caaagatgtt ccgcttgatt ttatcacagt gacctatgaa atcattgata agctatcaaa
     5641 gaaatatcat tatccgattc aagagtatct ctatgtaacc ttgacagatc atatttactg
     5701 ttcttatcaa gctctaactc aaggaaggta caaggatagt aatctgccag atatttccgc
     5761 taagtatcct gtcgcttttc aaatcgcaaa tgaagctttt gaaatttacc gtcagaagct
     5821 agcagatcat tttcctgagg acgaaattat tcggattgct tatcatttca ttaatgctga
     5881 aggtgaaaat gaagtggaac ttgtggagtc gattgataag aggaaagaaa ttctcaggaa
     5941 tgttgaagaa gttttaacgg actatgcaat tcaacgaact aaaaagaata accatttcta
     6001 tgatcgcttt atgatccatt tgaattattt cttggattat ttagacagat ctagagatga
     6061 taaccaatca cttctagata tggaagatca tattaaacaa tcctatccaa aagccttcga
     6121 gattggttcc aagatctatg atgtgattac gcaacatacg ggtcttgatt tgtataaaag
     6181 tgaacgagtt tatctagttc tacatatcca acgtttattg tcataaaaat ttatttaaaa
     6241 ctatataagg agaattctat catgaataga gaagaagtaa cattgttagg ttttgaaatc
     6301 gtagcctatg ctggcgatgc tcgttcaaaa ctattggaag ccttgaaggc tgctgaagtt
     6361 ggtgattttg aaaaagcgga cgctctggta gaggaagctg gtagctgtat tgcagaggct
     6421 caccacgcgc aaacaagtct attgactaag gaagcttctg gtgaggactt agcgtatagt
     6481 gtgaccatga tgcatggcca agaccacttg atgacaacta tcttgttaaa ggatttgatg
     6541 caccatttga tcgaacttta caagagagga gttaaataat gaacaaacta attgcattta
     6601 tcgagaaagg aaagcctttc tttgagaaac tatctcgtaa tatctatctt cgtgctattc
     6661 gtgatggttt cattgcaggt atgcctgtta ttctcttctc aagtatcttt atcttgattg
     6721 cctttgtacc aaactcatgg ggctttaaat ggtctgatga agttgtagcc tttctgatga
     6781 aaccttatag ctattctatg ggtattctgg ctctcttggt agctggtaca acagctaagt
     6841 cattgaccga ctcagtaaac cgtagcatgg agaaaaccaa tcaaatcaac tatatgtcaa
     6901 cgctgttagc agcgattgtt ggtttgttga tgttggcagc tgatcctatc gaaaatggtc
     6961 tagctactgg attcttgggg acaaaaggtt tgctttcagc cttccttgct gcctttgtta
     7021 ctgtagccat ctataaggtt tgtgttaaga acaacgtcac tattcgtatg cctgacgaag
     7081 ttccaccaaa tatctcacaa gtctttaaag atgtgattcc attcactcta tctgttgttt
     7141 ctctttatgc tcttgactta ttagcacgtc attttgttgg ttctagtgtg gcagaatcaa
     7201 tcggtaaatt cttcgcacca ctcttctcag cagcagacgg ataccttggt attaccatta
     7261 tctttggtgc ctttgccttc ttctggtttg ttgggattca tggtccatct atcgttgaac
     7321 cagctatcgc agctattacc tatgccaatg ccgaagtcaa cttgaacctt ctccaacaag
     7381 gtatgcacgc tgacaagatt cttacttctg gtacacaaat gtttatcgtt accatgggtg
     7441 gtactggtgc gacactggtt gttccattca tgttcatgtg gttaacaaaa tcaaaacgta
     7501 accgtgcaat cggacgtgct tcagtagttc ctaccttctt cggtgtaaat gagccaatct
     7561 tgtttggtgc acctcttgtt ttgaatccaa tcttcttcat tccatttatc tttgctccaa
     7621 ttgcaaacgt atggattttc aaattcttta ttgaaactct tggaatgaac tcattcactg
     7681 ctaatctacc atggacaact ccagctccac taggtctagt tcttggaact aacttccaag
     7741 tgctatcatt cattcttgct gcccttctaa tcgtggttga cgttgtcatt tactatccat
     7801 tccttaaggt ctatgatgaa caaattcttg aagaagaacg ttcaggtaag tctaatgatg
     7861 aattgaaaga aaaagttgct gcaaacttca acactgcaaa agcggatgct attcttgaaa
     7921 aagcgggtgt cgatgcagca caaaatacca tcactgaaga aacaaatgtc ctcgttctct
     7981 gtgctggtgg aggtacaagt ggactccttg caaatgcttt gaataaggca gcagcagaat
     8041 acaatgtccc tgtgaaagca gcagcaggcg gctatggtgc tcaccgtgaa atgttgccag
     8101 agtttgattt ggttatcctt gctcctcaag ttgcttcaaa ctttgaagat atgaaggcag
     8161 aaacagataa gctcggtatt aaacttgcta agacagaagg cgctcaatac atcaaattaa
     8221 ctcgtgatgg aaaaggtgcc ctagcattcg tacaagagca attcgattaa ggctaggaac
     8281 tgtgaaacag tctcccatcg ttacggaaat cgctatggcg aatttcctaa tcgccttatt
     8341 aattcgtcgg taaaaagata tcgtttttac ctcctcatgt cacaattcag tgacttggta
     8401 caagaagtga gatggagaag catggctcac tgactcctct cctctcactt ttactttatt
     8461 taaatcaaga aataggtgaa aaaaatgaca aaaacacttc caaaagactt tattttcggt
     8521 ggcgcaacag ctgcttatca agcagaaggt gctacacata ctgatggaaa aggaccagtt
     8581 gcttgggata aatatcttga ggataactac tggtacactg ccgaaccagc tagtgatttt
     8641 tacaatcgat atccagttga cctcaagcta gcagaagagt atggtgtcaa tggtattcga
     8701 atttctattg cttggtcacg tattttcccg actggttacg gccaagtaaa tgctaaaggt
     8761 gttgagtttt atcataattt atttgcagag tgtcacaaac gtcatgttga gccttttgta
     8821 actcttcatc actttgacac gccagaagct ctccactcaa atggagactt cttaaaccgt
     8881 gaaaatatcg aacattttgt agactacgct gccttctgtt ttgaagaatt tccagaagta
     8941 aactattgga caacctttaa tgaaattgga ccaatcggtg atggtcaata tttggttggg
     9001 aaattccctc caggtatcca gtacgacctt gccaaagtct ttcaatcaca ccacaatatg
     9061 atggtgtctc atgcacgcgc ggtaaaattg tacaaagaga aaggctataa aggagaaatt
     9121 ggtgttgttc acgccctgcc tactaaatat cctctagatc ctgaaaatcc agcagatgtt
     9181 cgtgcagctg agttggaaga tatcatccac aataaattca tcttagacgc aacttatcta
     9241 ggtcgctatt cagctgaaac catggaaggt gtcaaccata tcttatcagt caatggtggt
     9301 agtttggatc ttcgtgaaga agattttaca gcattagaag ctgcaaaaga cttgaatgat
     9361 ttcctaggaa tcaactacta tatgagtgac tggatggaag cctttgatgg agaaactgaa
     9421 attatccata atggtaaagg tgaaaaagga agctctaagt atcaaatcaa aggtgttggt
     9481 cgtcgtgtag ctcctgacta tgtaccacgc acggattggg attggattat ctaccctcaa
     9541 ggtttgtatg accaaatcat gcgtgtgaag aaagattatc ctaactacaa gaagatttac
     9601 atcactgaaa atggtctcgg ctataaagat gagttcgttg ataacactgt ttacgatgat
     9661 ggtcgtattg attacgtgaa acaacacttg gagatcttgt ctgatgcgat tgcagatgga
     9721 gctaatgtaa aaggttactt catttggtca ttaatggatg tcttctcatg gtcaaacggt
     9781 tatgagaaac gttatggtct cttctacgta gattttgaaa ctcaagaacg ttatcctaag
     9841 aaatcagctc actggtacaa gaaagtagcg gaaactcaga ttatagacta gtagaattag
     9901 tcattagata tagaatttta gtgagtcaaa aagatgttca aagattttat ccaatctatt
     9961 tatgaaaaaa agtttatatt ataaatttcg aaaaatgctc tcaaataccg tgtttgacga
    10021 gtgaagaatt gaaaagtctt ggaaaatggt atgtctcgac tggtaaagaa tggatttgtc
    10081 attcagatga tgagctggaa gaatttaaaa atctattttt aaattttatc aatcctgaag
    10141 aatgggatac tatctccttt gattcagatt ttatgccgtt tcaacaatcg taaccaattt
    10201 ctcaaaaaag ttaaatctta tatttagtac tctgtaaaac tcttatctaa tcacgttgct
    10261 tatactcaat gaaaatcaaa gagcaacttt aaactaggaa gcgagtcgca gatttctcaa
    10321 tgcatagctt tgaggaattg ggcaaaaagt ctttgatata gaaaaaagca tagtatcagg
    10381 tgttgaaaca cctgatacta tgctttttat tgtgggaaga tttacttttt ttcttctgaa
    10441 attgagttgt tacccaggct ctttcagttt attaaggctt gatgacttta atgtgtttag
    10501 atagcttaaa aaggattgaa tcacttagtt tagaatctga aacaatagta tcaagatttg
    10561 atatattata aaaagtataa aaatcaaact t
//
LOCUS       DAVHSI010000057        10432 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.058, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000057 DAVHSI010000000
VERSION     DAVHSI010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.058"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..609
                     /locus_tag="VVR21_001912"
     CDS             <1..609
                     /locus_tag="VVR21_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055708.1"
                     /translation="TVSQTVSLPNAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSH
                     EYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQHYQL
                     LLFHFQNKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLPYSNAKLEAT
                     NNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(646..2205)
                     /locus_tag="VVR21_001913"
     CDS             complement(646..2205)
                     /locus_tag="VVR21_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU6055709.1"
                     /translation="MHYEHSRKGKHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(2445..2762)
                     /locus_tag="VVR21_001914"
     CDS             complement(2445..2762)
                     /locus_tag="VVR21_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU6055710.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            2932..3474
                     /locus_tag="VVR21_001915"
     CDS             2932..3474
                     /locus_tag="VVR21_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU6055711.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            3474..4103
                     /gene="nth"
                     /locus_tag="VVR21_001916"
     CDS             3474..4103
                     /gene="nth"
                     /locus_tag="VVR21_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU6055712.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            4314..4835
                     /gene="pyrR"
                     /locus_tag="VVR21_001917"
     CDS             4314..4835
                     /gene="pyrR"
                     /locus_tag="VVR21_001917"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU6055713.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            4854..5777
                     /locus_tag="VVR21_001918"
     CDS             4854..5777
                     /locus_tag="VVR21_001918"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU6055714.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            5827..6906
                     /gene="carA"
                     /locus_tag="VVR21_001919"
     CDS             5827..6906
                     /gene="carA"
                     /locus_tag="VVR21_001919"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU6055715.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            7218..10394
                     /gene="carB"
                     /locus_tag="VVR21_001920"
     CDS             7218..10394
                     /gene="carB"
                     /locus_tag="VVR21_001920"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU6055716.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         3022 a         2095 c         2272 g         3043 t
ORIGIN      
        1 acagtctccc agactgtttc actcccgaat gctaaaatcg ttcttgatcg ctttcacatt
       61 gtacaacatc ttagccgtgc tatgagtcgt gtgcgtgttc aaattatgaa tcaatttcat
      121 cgaaaatccc atgaatacaa ggctatcaag cgctactgga aactcattca acaggatagc
      181 cgtaaactga gtgataagcg attttatcgt cctacttttc gtatgcactt aaccaataaa
      241 gagattttaa acaagctttt gagctattcg gaagacttga aacaccacta tcagcactat
      301 cagctcttgc tttttcactt ccagaataag gaaccagaga aatttttcgg acttattgag
      361 gacaatctta agcaggttca tcctattttt cagactgtct ttaaaacatt tctaaaggac
      421 aaagagaaaa tcgtcaacgc ccttcaacta ccctattcta acgccaaact ggaagcgacc
      481 aataatctca tcaaacttat caagcgcaat gcctttggtt ttcgaaactt tgaaaacttc
      541 aaaaaacgga tttttatcgc tctgaatatc aaaaaagaaa ggacaaaatt tgtcctttct
      601 cgagcttagc tttttttcaa cccactacag ttgacaaaga gccatttata aatcttctaa
      661 attaactagc ttcaaaccgt gttctgtcat gcgatagatg atcgagcaga cttcttttaa
      721 gaaacgacgg tcatgcgaaa cagtgatgag accgcctgga taggttgcaa agagttttct
      781 gatttggggt tgagaagtgg gagaaaagtt tcgtgtgggt tcatccagca ggagaaagtt
      841 tggtttgcgc aggactaaat ccaaaagcag gagttttccc tgttgtccgc cagataagga
      901 gcgaatttga tgctgcattt ctggataact gaaattgaga ctagctaggt gagattggat
      961 tttctgtagt tcctcttttt ccccagtttt gctgaggtag gctattggtg ataaatccaa
     1021 ttgcagtttt ttgtggtaat cttgtggcat aaaaccaagg gaaatctctc ttttatcatt
     1081 cagaagttgc tttaatttgg ctaatagagt tgatttccca acaccatttg gcccgataat
     1141 accgattttt tcttgcccac ggacagttag ttgtagtttt tgaaccaaaa ctcggtcgtc
     1201 aatggacaaa ttttcttttt ccagttggac taagacttta gaagctggta atggttggat
     1261 gtctgaaaag aaaagttgga tttgttcctc ttcaagtggc ttttgagtca tggactgagc
     1321 tgtcttttcg tagcgttttt cttgtgagag gacagttttc atctttttag ccaataggcg
     1381 accggcagta ctatctttgg tagctcgaag cgcagtttct acattttgct tgactctccg
     1441 atgtttttcc atggttttat cgtaggctct ttggttgtta gcagcttgct gactttgttt
     1501 ggcaaaatta gcctttctct gctcactata gctatcatag tctaaatgct ctactagcgt
     1561 ttccgcttct ttacggtgtt tgaccagtcg caagtgaaca atagtgtctg ccgtttcaga
     1621 aagaaagtct tcatcatggg aaatgaaaat aacggtttgc ctggtctttt gaatctggcc
     1681 ttttagccaa tcaactgtct caaggtctag gtcatttgaa ggttcatcta aaaatagaat
     1741 ctcaaagggt ttggctaact catggataag ctgaattttc aaagcttcgc cccctgatag
     1801 attgccaatc tcttggtcac ttgcgaaacg attgctatca aaatgcaatt cctccgccaa
     1861 acgatagagg atactgtagt ctaaatcaat agaatctaaa aagaagtagt cgtgtaaagt
     1921 tttctttttt aggtcctcag ggactttttg aggaatgtag gccagtgact gataatcaga
     1981 ctggatgtct cccttgatag tgaaatcaga caaatcttcc cccattaaag ttttaagtaa
     2041 ggttgattta ccatttcctt cttcgccaat aatagctacc ttttccccgt cttggatggt
     2101 catggttagg tcagatacaa gatctcgtaa atctttgttt tgtgtgatgg ttagatgatt
     2161 gatttttatc atatgttttc cctttctaga atgttcatag tgcataacaa aaaagctcta
     2221 ctttacctag tagagcccaa agtctatgtc aaaaaaactc tattaacatg ccagaaaaag
     2281 agcataaaag agcacacaaa aagagacaaa aacaagatct actaaataaa ggttctttat
     2341 ttgatagact tagttgttca tgtctccctt acctccgagt attagtatct ttatactata
     2401 cctttaagga aattttgtca acagaaaact ggaaattcta tgctctaaaa tccaaaaaca
     2461 ggtccataga gacttagtac gtgtttgaca tgctcgtaat ggattttgtc atagtttcgc
     2521 caagcagtgc gtgcttgatt gtttagtttt aggctaccca gtccaatcag aggactggtg
     2581 ggttggtaaa atttctcaag atcaattaag atactgttgt tcaacttttc cgtttttttg
     2641 agctcttgca tagtagtgtt tagcagctct tgtagtcgaa tatcatctgc cgtaccctgt
     2701 ttacagtttt ggtagctttt atttaacttg gataggagtt gaatgagttt cttgtcttcc
     2761 atgtgagcat cctccttgat ctgatgtact ctttccctat agtatagcac taaaaaacaa
     2821 aactatcatg gtaaatatgt taaaattttg aattttaatt acaaagtttg gtgtgctgat
     2881 ttgtagcctt ttcatggtat aatcaagaga gtaaatcttt atggaggaag tatgaaatta
     2941 aatattcaag aaattcgtaa gcagtctgaa ggtttgaact ttgaacaaac gttagattta
     3001 gttgatgacc tgcgtgcacg taatcaagaa attttagatg taaaagatat ccttgcagtt
     3061 gggaaagtac aatatgaaga ccgtatgtat ttcttagatt atcaactatc ttataccatt
     3121 gttcttgctt cgagtcgcag tatggagcca gttgagttag ttgaatctta tccagtcacg
     3181 gaagttttca tggaaggcgc aactaaccat ctaaatcaag aaattttaga tgatgacttg
     3241 gtcttgccca tcgaaaatgg ggcgcttgac cttgctgaga gtgtatcaga caatatcctg
     3301 ctaaacattc ctatcaaggt cttgacggct gaagaagaag ctggtcaagg atttgtctca
     3361 ggaaatgact ggcaaatcat gacagaggaa gaataccaag ctcaacaagc agtaaagaaa
     3421 gaagaaaaca gtccttttgc tggcttacaa ggactatttg acggagatga ataatggtct
     3481 tgtcaaaaaa acgagcacga aaggtgctag aagaaatcat tgccctcttc ccagatgcca
     3541 agcctagtct tgattttacc aatcattttg aactcctggt tgcggtcatg ttatcagccc
     3601 agacgacaga tgcagcggta aataaggcca caccaggtct ctttgttgcc tttccaacac
     3661 cccaagctat gtctgtagcg acagagagtg agattgcttc acatatttct cgcttgggat
     3721 tgtatcggaa taaagctaaa ttccttaaaa aatgtgccca acagttacta gacgattttg
     3781 atggtcaagt ccctcagaca cgtgaagaat tggagagttt ggcaggtgtt ggtcgcaaga
     3841 cagccaatgt tgtcatgagt gtaggatttg ggattccagc ctttgcagtg gatactcatg
     3901 tggagcgtat ttgcaaacac cacgatattg tcaaaaaatc agcgacgcca cttgaggtgg
     3961 aaaagcgggt catggatatc ttgccgcctg agcagtggtt agctgcccat caggccatga
     4021 tttattttgg aagagccatt tgccatccaa aaaatccaga gtgtgaccag tacccacaat
     4081 tatatgattt tagcaatttg taagatacta cattgaaact ttttgcttga ttttaagcat
     4141 gctttgtgct atagtaaatg ataactaaat attcctttaa acctgtcccg tgaggcaggc
     4201 aaggagcgcg ataaagtaga agggtgaagt ctatactgtg tgcagtaggg ctcgcttggc
     4261 tataaatttc aagtctcctt gtttaaggag acttttcttt ttggaggttt gtcatgaaaa
     4321 caaaagaagt tgtagacgaa ttgaccgtca aacgagcgat tacgcgtatt acttatgaga
     4381 ttatcgaacg caacaaagat ttgaataaga tcgtcttggc tggtattaaa actcgtggtg
     4441 tctttattgc ccaccgaatc caagaacgtt tgaagcagtt agaaaatctt tcagttcctg
     4501 ttgtggaatt ggatactaaa cctttccgtg atgatgttaa aagtggagaa gatacttctt
     4561 tggtttctgt cgatgtgaca gaccgcgaag ttatcttggt ggatgatgtg ctctatacag
     4621 gtcgtaccat ccgtgctgct attgataata ttgtcggtca tggtcgtcct gcgcgtgtga
     4681 gtttagcagt tctagtcgat cgtggacata gagaattgcc aatccgtcca gattacgttg
     4741 gaaaaaatat cccaaccagt cgttctgaag aaatcatcgt agagatgaca gaacttgatg
     4801 accaagacag agttctgatt actgaagaag cttagaaagt taaaggagta gccatgtcag
     4861 aaaatcaaca agcattgaac catgtggtgt ccatggaaga cctcactgtc gatcaagtaa
     4921 tgaaattgat caagcgagga attgagttta aaaatggagc ccagcttccc tatgaagacc
     4981 atccgattgt ttccaatctc ttctttgagg attctacacg gacacataag tcctttgaag
     5041 tcgcagagat taaacttgga ttggaacgac ttgactttga tgtgaagact agttcggtta
     5101 ataagggtga gacactttat gacaccattt tgactctgtc tgctttagga gtggatgtct
     5161 gtgtgattcg ccatccagag gtcgactact atagagaatt gattgctagt ccaacgatta
     5221 cgacttccat catcaatggt ggagacggtt cgggtcaaca ccctagccag agcttgcttg
     5281 atttgatgac catttatgag gaatttggcc actttgaggg tcttaaagtt gctattgcag
     5341 gtgacttgga ccactcacgc gttgccaaat ccaatatgca gattttgaaa cgcttgggag
     5401 ctgaactctt tttcgctgga cctgaggaat ggagaagtca agagtttgca gactatggaa
     5461 agtttgtaac cattgatgaa atcattgatc aggttgatgt catgatgttt ctccgtgtgc
     5521 aacacgaacg ccatgatagt ggagctgtat tttcaaaaga agactaccat gcccaacatg
     5581 gcttgactca agaacgttac gatcgtttga aagaaacagc aatcctcatg cacccagctc
     5641 caatcaatcg tgatgtagaa atagcagacc acttggttga agcaccaaaa tcacggattg
     5701 tccaacaaat gaccaatggt gtctttgttc gaatggcaat cttagaatcc gtactagcga
     5761 gtagaaacgc caactaaaac acaagacgtt aaaagacacc agtgagcgtc cacgagaggt
     5821 gaaaatatga caaaaagaat tctagtatta gaagatggca cagtttttga aggcaaggcc
     5881 ttcggagcag atattgatgt aacaggcgaa atcgtcttta atacagggat gaccggctac
     5941 caagaatcca ttacagacca gtcttataat ggacaaatct tgacctttac ttatcctttg
     6001 gtaggaaatt atggtattaa tcgtgatgat tatgaatcca ttattccaac ttgtaaggga
     6061 gtcgttgttt ttgaagaagc gcgtagagct agcaactggc gcaaccaaat gaccttggat
     6121 gaatttttga aagccaagaa aattccaggg atttcaggaa ttgatacgcg tgctcttacc
     6181 aagattatcc gtaagcatgg tactatgcgt gcaaccttga cccatgttgg ggacagtatg
     6241 gaccatgtga cggaccagct ccaagcaaca gttttaccga cagacaatat caaacaggtt
     6301 tctactaaaa cgtcttatcc agctccagga gttggtttga gcgtggtgct agtggacttt
     6361 ggtctcaagc actcaatcct acgtgaactt tctaaacgca actgtaacgt gacagttgtt
     6421 ccttattcga caacggctga agaaattctc catctcaatc ctgatggagt tatgttgtca
     6481 aatggtccag gtaacccaga agacgttcca caagcactcg acatgattcg cggtgtacaa
     6541 ggaaaaattc caatctttgg tatttgtatg ggacaccaac tctttgcaat ggcaaacggg
     6601 gctaagacct ataagatgaa gtttggccac cgtggattca accatgcggt acgtgaaatc
     6661 gcaacaggac gagtagactt caccagccag aaccatggtt atgcagtcag ccgcgaggat
     6721 ttgccagagc acttgattat tacccacgaa gaaatcaatg acaagtcagt ggaaggtgtg
     6781 cgccacagat accaacctgc tttctctgtt caataccacc cagatgcagc tcctgggcca
     6841 cacgacgcta gctacctatt tgacgagttt atcgagatga tggaagtttt taaacaatca
     6901 aactaagaac gagtaaaagc tcgtcggaga atttatgtaa ctgaacacgg acggaaagct
     6961 cagaatgtag agaaaccaac ttggattgtc aatccttcct tgatttccta aaattcaatc
     7021 gctttctatt cgtcctttgt atcttattta atgtcgccct gagaggcgac gaatagaaag
     7081 gagaagatac attgttcgcg gaagtgaaca cgccctaaga actgtgtgaa aaagataaac
     7141 atcgtcttga cgctgaaggc gtctgcgccg agtttcctat tttcactgtg ttctttacgg
     7201 gctttgtatc ataaactatg cctaaacgta ctgatattca aaaaattatg gtgattggtt
     7261 ctggtccgat tattattggt caggctgctg agtttgacta cgctgggacc caggcttgct
     7321 tgtcgttgaa agaggaaggt tatgaggttg ttttggttaa ctcaaatcct gcaaccatca
     7381 tgacggacaa ggaaattgct gacaaggttt acattgaacc gattacactt gagtttgtga
     7441 cacgtattct tcgtaaggaa ggtccagatg ccttgctacc aacactcggt ggtcagacag
     7501 gtctcaacat ggccatggaa ttgtctaaaa atggtatctt agatgagctt ggcgttgaac
     7561 ttctgggtac caaattatct gccattgacc aagcggagga ccgtgacctc tttaaacaat
     7621 tgatggaaga gcttgaacaa cccattccag aatctgaaat tgttaacaca gtagaagaag
     7681 cagttgcctt tgcagcgaca attggctacc cagtcatcgt tcgtccagcc tttaccctcg
     7741 gtggtactgg tggtggtatg tgtgccaatg agaaagaatt gcgtgaaatc actgaaaatg
     7801 gtttgaaatt gtcacctgtt acccaatgtt tgattgagcg ttcgattgcc ggtttcaagg
     7861 aaattgaata cgaagtgatg cgtgactcag ctgacaatgc cttggttgtt tgtaacatgg
     7921 aaaactttga cccagttggg attcacacgg gggattccat tgtatttgcc cctgcgcaaa
     7981 ccatgtcaga ctatgaaaac caaatgcttc gtgatgcgag cttgagcatt attcgtgccc
     8041 tcaagattga aggtggatgt aatgttcagc tagctcttga tcctaacagc ttcaagtatt
     8101 atgttatcga agtaaaccct cgtgtatcac gttcgtcagc ccttgcttct aaagcgactg
     8161 gatatccgat tgctaagttg gctgccaaga ttgcagtagg tttgaccttg gatgaggtta
     8221 taaacccagt tacaggttca acctatgcca tgtttgaacc agcccttgac tacgtagttg
     8281 ctaagattcc acgtttccca tttgacaagt ttgaaaaggg tgaacgccgt ctcggtacac
     8341 aaatgaaggc gactggagaa gtcatggcaa tcggtcgtaa tatcgaggaa tctcttctca
     8401 aggcctgccg ctcccttgaa attggggtgc accacaatga aatacctgaa cttgcagcag
     8461 tttctgatga tgccttgatt gaaaaggttg tcaaagccca agatgaccgt ctcttctacg
     8521 tatcagaagc aattcgtcgt ggctacacac ctgaagaaat tgcagagctt acaaaaattg
     8581 atatcttcta tcttgataaa cttttgcata tctttgaaat tgagcaagaa ttgggtgctc
     8641 atccacaaga tctagaagtt ttgaaaacag ccaaacttaa tggtttctca gaccgtaaga
     8701 ttgctgaact ctggggaacg actgatgatc aagttcgcca acttcgcttg gaaaacaaga
     8761 ttgttccagt ttataagatg gtagacactt gtgcggcaga gttcgactcc gaaacgccat
     8821 atttctattc aacctatggt tgggaaaatg aatctatcag atctgataaa gaatctgtac
     8881 ttgtcctagg ttcaggtcca atccgtatcg gtcaaggggt tgagtttgac tacgcaaccg
     8941 ttcactctgt taaggctatc caggcagctg gttatgaagc tatcatcatg aactcaaacc
     9001 cagagaccgt ttcaacagac ttctctgtat cagataagct ttactttgag ccattgacat
     9061 tcgaagatgt tatgaacgtc attgacttgg aacaaccaaa gggagttatc gttcagttcg
     9121 gtggtcaaac agccatcaac cttgcggagc cattggcaaa agcaggtgtg accatccttg
     9181 gtacacaggt tgctgaccta gaccgtgccg aagaccgtga cctcttcgag caagctctca
     9241 aagaattgga tattccacag ccaccaggac aaacagctac caatgaagaa gaagcagctc
     9301 ttgcagctcg caagattggc ttcccagttc ttgtccgccc atcttatgta cttggtggac
     9361 gtgccatgga aatcgttgaa aacgaagaag accttcgttc ttacatgcga actgctgtta
     9421 aggctagtcc agaccaccca gttcttgtcg actcttatat cgttgggcaa gagtgcgaag
     9481 ttgatgccat ttcagatggt aaagatgtac tcattcctgg tatcatggag catatcgaac
     9541 gtgctggtgt ccactcaggt gactcaatgg ctgtttaccc accacaaacc ttgtcgcaaa
     9601 aggttcagga gaccatcgca gactacacca aacgcttagc aatcggtctt cactgccttg
     9661 gaatgatgaa catccagttt gttatcaagg atgaaaaagt ctacgttatt gaggtcaatc
     9721 cacgtgccag ccgtactgtt ccattcctat ctaaggtaac caatattcct atggctcaag
     9781 tagcgaccaa gctcattctt ggtcaaagtt tatcagaact tggctaccaa aatggacttt
     9841 accctgaaag cacccgtgtt catatcaagg cacctgtctt ctcctttacc aaactagcta
     9901 aggtagacag cttgctcggt cctgaaatga agtcaacagg tgaagttatg ggttctgatg
     9961 ctactttgga aaaagctctc tataaagcct ttgaagcttc ttatctacac ttgccaactt
    10021 ttggtaatgt cgtctttacc atcgctgatg atgccaaaga agaagccttg aacttggctc
    10081 gtcgtttcca aaacattggt tatggaatcc ttgcgacaga agggacagca gccttctttg
    10141 ctagccatgg cttgcaagcc caacctgttg gtaagattgg tgatgacgat aaggatatcc
    10201 caagttttgt acgcaaagga agaattcaag ctatcattaa cacagtagga acaaaacgaa
    10261 ctgctgacga agatggtgag caaattcgtc gttcagccat tgaacacggg gtgcccctct
    10321 tcacagcgct agatacagct aatgccatgc ttaaggtact tgaaagtcgt agctttgtta
    10381 cagaagcgat ttaaatagaa aaataaggta tagcagactg aatttagaac ag
//
LOCUS       DAVHSI010000058        10273 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.059, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000058 DAVHSI010000000
VERSION     DAVHSI010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10273
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.059"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1017)
                     /locus_tag="VVR21_001921"
     CDS             complement(<1..1017)
                     /locus_tag="VVR21_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU6055717.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNTGMLLMDVVKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYL"
     gene            complement(1026..2246)
                     /locus_tag="VVR21_001922"
     CDS             complement(1026..2246)
                     /locus_tag="VVR21_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEU6055718.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQYTMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKTMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(2277..4721)
                     /locus_tag="VVR21_001923"
     CDS             complement(2277..4721)
                     /locus_tag="VVR21_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEU6055719.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDTVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNTGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLIANRYRDLWWEFHDLEWSQILQHHMGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPEVVFHIAAWTDMGDKLKQLAVYNNVRLHPQIVPPVLD
                     KLERSVDLYLDINYSHVVGTILEDMKILEKPIPSFDTTEHGNTGQLVFKKDEVSVMVQ
                     AIKDYRRDGRFLSCYEGSDFHCLTFTNSQELQKIDYLVKNFPMVTFHIAAWTVMGPML
                     QELAKKYKNVKLYPEVKSDQFEELKSQMDVYLDINLHNSTSEVVKEISSLNKPMLAFY
                     TSQNGNHGQHLYSSEHPERLLQAFHALIKGETLGEPEKPIKVIGIDQTLDYVIKNKSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAENRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(4731..5741)
                     /locus_tag="VVR21_001924"
     CDS             complement(4731..5741)
                     /locus_tag="VVR21_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6055720.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNEGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAEFIV
                     DQGLGFVANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(5770..6645)
                     /locus_tag="VVR21_001925"
     CDS             complement(5770..6645)
                     /locus_tag="VVR21_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6055721.1"
                     /translation="MGNELISIVVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(6685..7563)
                     /locus_tag="VVR21_001926"
     CDS             complement(6685..7563)
                     /locus_tag="VVR21_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HEU6055722.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLSNICFHIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVACRNFENFHVSSGKLILNDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLCVKRRD"
     gene            complement(7560..8960)
                     /locus_tag="VVR21_001927"
     CDS             complement(7560..8960)
                     /locus_tag="VVR21_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000543101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU6055723.1"
                     /translation="MHALVDAMSERITLLANMGYPLEKHLAIYRQMLEFSLANGQASG
                     LSDTATYKEFEMKKRLLNQLTVQESSEKKAIVLAANYAYVDQVLTTIRSICYHNRSLR
                     FYLIHSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFV
                     QEDKALYLDCDLAVTKNLDDLFATDLQDYPLAAVRDFGGRAYFGQEIFNAGVLLVNNA
                     FWKKENMTQKLIDLTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQ
                     LPEGQDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIY
                     PIKEPFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNG
                     IHYLVDVDNELVETSQVLLDINHGEKTEEILDQFANLGKPILSFENTKTYEVGQEAYA
                     VDQVQAMIEKLREISK"
     gene            complement(9007..10273)
                     /locus_tag="VVR21_001928"
                     /pseudo
     CDS             complement(9007..10273)
                     /locus_tag="VVR21_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         3112 a         2171 c         1697 g         3293 t
ORIGIN      
        1 taaataaact atagaatcgt ctaatagcca atcaattcta ctatgtaata cattttgata
       61 tactgttaca ttcgtatact gtgatagaga ggtcagctcc tcagaacaat cacacggtgc
      121 agccaaatga aaatgccaat caggtaaccg ttgtactaaa tactctaaat gttttatatc
      181 tgcactccat gtcacaagca tcacttgttt tttagactga ttgcttcttt caaaataatt
      241 taaatcggaa cgttgaaaag caatctctga ccaatccaaa tctctataaa cccaccataa
      301 ttcacgtagt ctagatatac tatatgtatt ccaaggttta tcatgactag catagtgaac
      361 aattgtaggt ggattgtcat ctagacgttc acattcttga gcaaggtgat aaatatcaac
      421 acccaccata taattatatg ttttatctaa ggctagccaa ttatcctcaa aataaatatt
      481 taaaatactc tgatccccaa gatgaacaac ttgattctgc tcggccgcta attccaataa
      541 actattgact atagaatgtt ctttccattt tacaacatcc attagtaaca taccagtatt
      601 aaatccagat tttcgtcctt cataggcata gacatcatca acagcaccaa ttgaatatcc
      661 tttgagatct atctcaaaca aagtagctag ttccccagtt acaatgatat cggaatccag
      721 atacaatacc ctatcagatt caaccacttc tgtcgcaaaa aatctaaagt aagaagcata
      781 atttatatga ggtcctgttt tgtagctttc aaaaagttct ttatcaatgt gtacactgcg
      841 aattgtagaa ttcacaactt ccatttttct ccccaataat ttaaaccatt caggagctat
      901 atcactgttg agaatataaa aatcaacatc tctattgtga tacaatacag actttatagt
      961 cgtctctaaa ggaataagat aggcattatc tgccgctaat actattgatt ttctcatact
     1021 gttctctacc tcatgtaaga tctgattgct gcaaccattt ttttcggaat ggagcttgga
     1081 tagatacctt catatgaaat ctcagaaaga ttttcagagc aagtattgtc gaaagctatc
     1141 attgtttttt tgtacttaag cacaaactca tatgcatctt ctaattttcg atcatgattc
     1201 aaatccaaat acaaatctga agctattact atttgttcca ataacattgg taaggaattt
     1261 ggatatacgg taacattagg aaaacgcgtt aaagctagta gttcatttgc catatttgta
     1321 taagcaacaa tatgaaaatg aacttctggc aattgctccg ccaaataatc gattttctcg
     1381 acacaccaag aattcgttaa attaacacat tgcaacttaa atatttgtga tttactagga
     1441 tacttcacac tctttgaaaa ccattcattt aaaataacag accaatccat caaagagtat
     1501 tcccaccaaa cttctcttag acgtccaaca gaaaattgat tccaaggctt atcctgagaa
     1561 atatagtgta aaattagtgg cagtggttcg agcggaatat caaaaatgaa ttgatgttta
     1621 aaggctgccg ccccataatc atatcctatt tgaaaattat attgatcttc aagggaacta
     1681 tattgatctt taaacaacat attcaaaatt gactggtctc cttcttccac attctcatgt
     1741 tctttttctg ttaagtcaat caatttttgt cgaatagttt cagatcccca ttttttgttg
     1801 ttaatcaaga gaacaccagc attgaagccg actcctgctc caaagcaaga acgagctgct
     1861 gccaaataat tttcacctaa gtctaattca aacaaatcgg tcaaatcacc agtcacaatc
     1921 aaatcactat ctagatagag aactttatct tctgttacaa aatctggaat aaaatagcgt
     1981 gcaaaggtca tatgattgat atgaggcagt ttattagacc agttcattgt atactgtgag
     2041 ccaatcaact tgcaatcaat caagtcgccc cccatctctt gtaaatatat tcttatttga
     2101 ctaaaccatt cctggggaat gtcctgattg agcaaataaa ttttcaaatg actattgtgt
     2161 ctacagagtg acttcattgc cgtttcgatt tgtcgaatat aagcgtaatc acctgcaaat
     2221 actacagcgc gtttggtatt tctcatttta aatccttatc atttatttta aatagtctag
     2281 tttaatattc gtgcaacaat ctgactgtta taggtttcat catcaataaa ttcaatatct
     2341 tggtcgaaat tatgttctgc agtatgttta tgagaaaatt taaccttagt tttagctccc
     2401 attttcatcc attcatactc tgagtcaata tggcctacat ccaaaacttg atagcccatc
     2461 tggcatagat tataactcag aacttttgct gtaggaccca gcatacataa aataaggcga
     2521 ttttcagcat gtttcataat ttcctcttga atgttatcga caacggaata agcattatga
     2581 gatggacaaa taatcctttt cacagatttg accttatcaa ataaatcatt tccaacccca
     2641 gagcgagatg taatcccctc tacaatcaga atatccctat tctcccaaat actctttagc
     2701 ttttcaaatt gtccttttgc cttactctta tcttcataat caatgtatgg acgcgagata
     2761 aaggtagagc cataccatga acccttacac aactctttat aaaaatccat ataaacattc
     2821 atatgttctt tccagaatgg tgtagcccac caagtaaaga caaaacgatc gtcaaaagca
     2881 tcaggtaaac aaaccactaa tttctcgtca ctctcaagac ccacaatatg ttttaattgg
     2941 ttagctaact ctagatcatg attttgataa ggtataggca aaccccacat caaattgact
     3001 tctccgtctc caaaacgaac taatgaggac ttatttttga taacataatc cagagtctga
     3061 tcaattccga taaccttgat tggcttctct ggttctccca aagtctctcc ttttatcaat
     3121 gcatgaaatg cttgaagaag cctttctgga tgctcacttg aatataaatg ttgaccatga
     3181 tttccatttt gtgaagtata aaatgccagc attggtttat tcaatgatga tatctccttg
     3241 acaacctcac tagtagaatt gtgtaggtta atatccaaat aaacatccat ttgagatttg
     3301 agttcttcaa attgatcgct tttcacttca ggatatagct taacattttt atattttttt
     3361 gctagttctt gtaacattgg tcccataact gtccaagctg cgatatggaa tgttaccata
     3421 ggaaaattct taacaagata atctatcttt tgcaattctt gagaatttgt aaatgttagg
     3481 caatggaaat cactaccttc ataacaactt aggaatcttc catctcttct gtaatcttta
     3541 atcgcttgaa ccatgactga aacttcatct tttttgaata ctagttggcc agtattccca
     3601 tgttcagtcg tatcaaatga tggaattggc ttttctaaga tcttcatatc ctctaaaata
     3661 gtacctacca catgactgta gttaatgtcc agatataaat ctacacttct ctccagctta
     3721 tctaatacag gaggaacaat ttgtggatgc aatctcacat tattatatac agctaattgt
     3781 tttaatttat ctcccatatc cgtccaagct gcgatatgaa ataccacctc aggtagagct
     3841 gtaactagct cttctattcc ttctaaatct tgggaattcg ttaaggttaa gcaagaaaat
     3901 tccttatcta gaggcgatat tagttcaaat tctcccatat ggtgttgtaa aatctgactc
     3961 cactccaaat catggaattc ccaccataaa tcacgataac gattggctat caaggtggtc
     4021 cagggttttc tgtaggtcgt aaaatgaatc accactggtt tatcgttaaa agccagatgt
     4081 tcctgccaat tattatacaa agccacaata tcatgcccta cttgtaaatt ataagctcga
     4141 cctagctcta accaatcatc ttgcaagact tgattgaaaa tcgtttgatc accattaaaa
     4201 tgctcgaaac ggccttcttc aacttccttc attgtaacaa tgctctgttc aattagtcgt
     4261 tcttttaatt tctcttgacg ccatttttta ttgttgatta atagaacacc tgtattaaat
     4321 gtaattccat ctgtatcttt aactgctgcg agtgattttt cttctaaaca aatactaaat
     4381 aatttctcta aagaagtatt tacaatcaaa tcactgtcta aatataaaac cgtatcttct
     4441 tggatataat ctgcaataaa atatctagca taggtaatgc tactaatgtg atcttgcttt
     4501 tcccaatctt gaaacacagt ttgttcaggt agtttaacat cgataatctc actacctaac
     4561 atgcgagcta tttttcgtgg tttgcgaaac caatctggca taatatcttg atttaaaata
     4621 taaatcttaa catctcgatt gtggtataaa atagatttta tggttgtttc taactgcctg
     4681 atgtaattac gatcaccagc taatacaatt gttttaatca tcttgttctc ttattcaact
     4741 cccaaatggt aaattgcatc taccaataat tttttagtaa aataaccttc ttttagcaaa
     4801 taactaaagg tttttatccg attcgtcatt tcttgatatt cttgtagatt cattttatca
     4861 actatctcat gaacttcctc tagactattc gccacaaagc ctaagccttg atctactata
     4921 aattcagcag ttgacaagct acttggtaca atgactggga tgcccgctgt cagataggta
     4981 ctcaccttat gagatatatt caaggtatag tattggttac tttctccctc attttgatgg
     5041 gttccccaga caaggccaaa tccacccttt gataattcta gcaacaattc ctcatctttt
     5101 ttccatcctt cgatgctgag atttctagca ctagaactag cttccccttt atttgaaaat
     5161 actctcaaag gcgtatcttg agaccaattt tgtaagtctg gaaaacgctc taaacttcca
     5221 gcaaaaaaaa gttctttttt aaaagcaggg gtgtataagg ataaatcatg aggatgatcc
     5281 cacatccctt gaacaagaat cttcttagtc gtcaatcctt cttccatcag gcgtgttttc
     5341 attctctctg atggcactat caaaacatct gatagattat acatgtacat atagtctttc
     5401 atgagataat agttactatc aaacatgagg ggaacaacat catggataaa gcaaataatt
     5461 ttcacctgca tatcctttag cttgtcaaac aagagacgat caaattcaaa gccattccag
     5521 gttggagact gaaagactaa aatatcccca atagagatac tggccataat accatccaga
     5581 cgcttattca tttcagaagg actatctgaa gcaatgttgt aaaaataaat accaacctct
     5641 ctaaatccca gttgactagc tatcttttga acagcatttt gagctaagat aaccgtacta
     5701 tcaccagcca tgccgtataa atttgttaaa tgtaatttca tattacgcta tctcattttt
     5761 tattactatc tacggaagta aagacaattt ttccatcatt cttctataaa tctctgtgaa
     5821 ctgcatattt tgttcttcta attttgctat cactctttgt aatctatttt tataaatcaa
     5881 aatatgattg gtcaagtcat agtctgaact tgctaaaata gctatctttt cttccctagc
     5941 cccaatttca tcatacatac gcttttcact ccatgtattc gataaagtat cagataaacc
     6001 aacacggtac cagtaaacac aacgattcaa atagactatc ctcgaagctc ttagaagtac
     6061 cttccatgtc cagtaagtat cctctgcaat ttttcctata ggaaatggta aatcttgtag
     6121 taactctctc ttgaataact tcaagacagc tacagtccag ttcccatttc tgacttcttc
     6181 gacaccttcc ctatccatga ttgctttacc ttctatcact tccagagaat catctggatc
     6241 cgtaacataa gtcatataca catagcgtgt ttcatcataa gaattataac gcccgatact
     6301 aatatctgcg ttttcctttt tcaaagcacc atataatcgg tctaaagcat catgttccaa
     6361 ccaatcatca gagtctacaa aagtaatgta cgcccccccc gaacattcaa tacctaggtt
     6421 acgagctgat gaaagaccgc cgtttgcttt ctcaaaatat ttgaaacgag aatctttctc
     6481 tacaaattct tcacatattt tggatgaatg atctggagag ccatcattga ttaataaaca
     6541 ctcaaaattt tgatacgtct gattctgaat gctatccaaa cacattcgca aataattctc
     6601 aacattgtag attggaacta caatactaat taattcattt cccatatact aactttccta
     6661 gacttgattt attctatttc cctcttaatc tcttcttttt acacaaagat tgccattatt
     6721 ataaactaca ctgtttgatg gaatatcatt gcgtatgaga caacctgctc caataatggt
     6781 attatctcca atcgtcactc cttttaaaat cgtgacatta cttcctatcc agcagtctct
     6841 gccaactcta atcggcgctg tagtccactg ccacttttca atcttttcag cggtataaat
     6901 atggtcgtga tcataaaaac gaacaccctc tcccatcatg gtaccagctc cgatttcaat
     6961 tctttccata cagttaaaac tacaagagtt gttgataaaa acaccatcat tcaggattaa
     7021 cttaccagaa gagacatgaa aattttcaaa atttctacag gcgacattgg ctcctacaat
     7081 gaagtgagcc ttatcatcga ttttaaagac attccaagtc ccatcttgaa tgattttctc
     7141 ttgatgattg gtgcctactc tgacttcatt cagatagtct ctcactctag aaaccaattt
     7201 gtctggtgta cttgatagaa aaacttcctg cccctgattt ccatggactg tattgtcaaa
     7261 tgcaaagaca gattttccag cctgtacaaa cttggagaca atagcatcta cttcttgaaa
     7321 gtgattgata tctagtaaaa agtcacaggt atcgactaaa aagtttagct gttcttcatt
     7381 tgtaatcgtt cggagacgga cattatagtt cgtttctaag ctacggattt tctcggaaaa
     7441 ttgaacaggt gctgcaatat gaaaacagat atttgacaag gattcaagga gataatccaa
     7501 ctcttcaatc tgatcactaa ccgtcaaaat cagagcatct cctactaaat gatttttctt
     7561 catttgctta tttctctcaa tttctcaatc attgcttgaa cttggtcaac agcatatgcc
     7621 tcctgaccta cttcataggt tttagtattt tcaaaggata agataggctt gccaagatta
     7681 gcaaattgat cgagaatttc ttctgtcttt tcgccatgat taatatctaa aagtacttga
     7741 ctggtttcta ccaattcatt atcgacatct accaaatagt gaattccgtt aaatatagtc
     7801 acgtttggat aaattgtcat ctgagccaat cgatcactaa ctattactct agctgctatc
     7861 ttaaactgaa tatcaggcaa ggattgaacc aatgtctcaa tttgttcaat atggtctgag
     7921 gcagtataga ttagacaagt gaaaggttcc tttattggat agatgtgaga tctttgtaat
     7981 ggatgtaaat gatggttttg tcccaattct gtccattcaa gcccatgata gtaccaccaa
     8041 acttcacgat aagtttgggc cgccaaatct ttccacggtt ttctatggga aagatagtga
     8101 ataatagcag gataatcctg accctcaggc aattgataat cagcaaactg tttatgaatg
     8161 acaatatgat tataatcaaa atccaattcc agccatttat gttcaaaaag catattcaag
     8221 atgctctgat ctgcctgatc caccttatca tgccattcat tggttaaatc aattaatttt
     8281 tgggtcatat tctctttttt ccaaaaagca ttgtttacca agagaacacc ggcattaaag
     8341 atttcttgac caaaataagc tctgccccca aaatctctaa cagcagccaa aggataatct
     8401 tgtaagtctg tagcaaacaa gtcatccaga tttttcgtta cagctagatc acagtccaag
     8461 tagagggcct tgtcttcttg cacgaaatca gctatgaaat agcgtaaaaa gactgtgtaa
     8521 ctaatatccg atttataaca tgaaatttgc tcagaagtta cccgacaatt aataatttct
     8581 gagtcaaact tctctaatcg cttatttaat tgtttgatcc attcatttgg aaaatcgcta
     8641 tgaatcaaat aaaaacgaag cgagcgattg tggtaacaga tagacctgat tgtcgttaaa
     8701 acttggtcta cataggcata attcgccgct aggacaatgg ctttcttttc acttgattct
     8761 tgtaccgtta actgatttaa aagtcttttt ttcatttcaa actctttata cgttgctgtg
     8821 tcagataaac cactagcttg accgttggcg agactgaatt ccaacatttg acgataaatc
     8881 gccaaatgct tttctaaagg gtaacccata ttagctagta gcgtaatgcg ttcggacatg
     8941 gcatcaacca atgcatgcat ccacttttct gtccaaactc ttgataaact accttttcta
     9001 atccgattat tcttcatcat cacgtttacg gcgtttcgca aacaaaccca agccagtcac
     9061 agctgccaaa gctccaagga gtacagatga cttggaagct tctgtacctg tatttggcaa
     9121 ttgctgtctt gacttacctg ctgaagttga cgcgcttgcg cttgttgatg ccgattcaga
     9181 cgctgaagct gaggcacttg tacttgctga agctgatgca ctcgttgacg ctgactcaga
     9241 agctgatgtg cttgctgaag ccgaggcact ggtgcttgct gaagctgacg cactggttga
     9301 tgctgaagct gaggcgctgg ttgacgctga agctgaggcg cttgtcgatg ctgaagccga
     9361 cgcactcgtt gatgctgaag ctgaggcact cgttgacgct gaagctgagg cgctggttga
     9421 cgctgaagct gaggcgcttg tcgatgctga agccgaggca ctcgttgatg ctgaagctga
     9481 ggcactcgtt gatgctgaag ctgacgcact cgttgatgct gactcagacg cacttgtgct
     9541 tgctgaggct gacgcactcg ttgatgctga ctcagacgca ctcgttgacg ctgaagctga
     9601 cgcactcgtt gacgctgaaa ctgaggcgct tgtcgatgca gattcagacg ctgaggtgct
     9661 tgctgaggct gaagcacttg ttgacgctga ggccggaggc gcttgtcgat gctgaagccg
     9721 acgcactcgt tgatgctgaa gctgaggcac tcgttgatgc tgaagctgag gcactcgttg
     9781 atgctaaggc tgaagcactt gtcgacgctg aagctgacgc actcgttgac gctgaagctg
     9841 aggcactcgt tgatgcagat tcagaggcgc tggttgacgc tgaagctgag gcgcttgtcg
     9901 atgctgatgc tgatgcgctt gttgatgcag attcagaggc gcttgtcgat gctgaagctg
     9961 aggcactcgt tgatgctgaa gctgaggcac tcgttgatgc agattcagag gcgcttgtcg
    10021 acgctgaagc cgacgcactc gttgatgctg actcagacgc acttgtactt gctgaagccg
    10081 acgcactcgt tgatgctgag actgatgcgc tggtacttgc tgaggctgac gcactggttg
    10141 acgctgaagc tgatgcgctt gtcgatgctg aagccgacgc actcgttgag gctgaagctg
    10201 acgcactcgt tgaggctgaa gctgacgcac tcgttgatgc tgactcagac gcacttgtac
    10261 ttgctgaagc cga
//
LOCUS       DAVHSI010000059         9788 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.060, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000059 DAVHSI010000000
VERSION     DAVHSI010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.060"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            212..1657
                     /gene="cps4A"
                     /locus_tag="VVR21_001929"
     CDS             212..1657
                     /gene="cps4A"
                     /locus_tag="VVR21_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU6055724.1"
                     /translation="MSRHFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            1659..2390
                     /locus_tag="VVR21_001930"
     CDS             1659..2390
                     /locus_tag="VVR21_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEU6055725.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            2399..3091
                     /gene="cpsC"
                     /locus_tag="VVR21_001931"
     CDS             2399..3091
                     /gene="cpsC"
                     /locus_tag="VVR21_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU6055726.1"
                     /translation="MEKQNTLEIDVLQLFRSLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVSRDQGEKSGLTNQDLQAGSYLTKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVAVPVDTRIVSISVNDQVPEGASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKLNTLIGFLVGLIVINVTVLLLELLDTRVKRPEDIEDALQMT
                     LLGVVPNLDKLK"
     gene            3101..3775
                     /locus_tag="VVR21_001932"
     CDS             3101..3775
                     /locus_tag="VVR21_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU6055727.1"
                     /translation="MPTLEIVQKKLEFIKKTEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSINIAWSFARAGYKTLLIDGDIRNSVMSGVFKSREKITGLTEFLSGTTDL
                     SHGLCDTNIENLFVVQSGAVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGVVI
                     DSAIITQKCDASILVTATGEVNKRDVPKAKQQLEQTGKLFLGVVLNKFNVQHEKYGSY
                     GNYGKR"
     gene            4179..4772
                     /locus_tag="VVR21_001933"
     CDS             4179..4772
                     /locus_tag="VVR21_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU6055728.1"
                     /translation="MYSILKRLGDISISLIVITLFCPFFILIAIAIKFDSKGPVIFKQ
                     KRFGIHKKTFYVFKFRTMKVETPKNVATRDLQNPEQWITRVGTFLRKTSLDELPQLCN
                     ILVGDMSIVGPRPALWNQFDLIEERDKYGANDILPGLTGWAQINGRDNLSIDMKAELD
                     GYYVTHKSLLMDIRCIVRTIPYVLKRKGIVEGSQKES"
     gene            4781..6007
                     /locus_tag="VVR21_001934"
     CDS             4781..6007
                     /locus_tag="VVR21_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6055729.1"
                     /translation="MKILFVSQHYRPEPFRLSDICEDLVERGHEVTVLTGIPNYPEGK
                     TYADYRNNKNRRETIEGVTVFRSYTIPRGKSTLHRILNYFSFAISSSIGVLLGQYKAK
                     DGSEFDCIFVNQSSPVMMAWAAMAYKNKYKKPMFLYCMDVWPDSLTVGGVKQDGLIFK
                     LFKFISKKVYRASDYIFVTSPSFKNYFVNQFDITEQKITYLPQYAEDLFIPDESRVNK
                     ESVDLTFAGNIGKAQNLETILKAASLIEKNTDLPKKIQFHFVGDGTELLSMKALAHEL
                     ELKNVSFYGRRSLEEMPTFYKKSDAMLVSLIGDSIVSRTIPGKVQSYMAAGKPIIGAI
                     SGDTKTIVEEAKCGFVSPEQDVEQLAQNICKFSMLSTEEQRELGKQARCYYGKHFSKE
                     QFMTQLENYLREGFSS"
     gene            6238..7443
                     /locus_tag="VVR21_001935"
     CDS             6238..7443
                     /locus_tag="VVR21_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HEU6055730.1"
                     /translation="MESRKKFVCFPNSSLRFYILQAAIALSILSQAPYIWKFSGIPTQ
                     LLIMPLWILLGVVSIFSRIDMERSFLFFLLTIGCLISTIALLDIVTGVSYVFNGLSQQ
                     LYLAVGILVLGYWNADVIVHYWKIITMTFLGACLLISVDIYFHYFQGHTFSNIDYVYR
                     AKNSAASIFLSAVILNLSLYNRKWALWRKVLLLASSGLLIYMCILMRSRAVLLAAAVL
                     PLVYIWFQETSLGHKIGRTLGVSTVVGAFLLNSAIYDFFINNLFLRVTSEYRPSSLTL
                     DYVSSNRFVYFEIFAKEISGHELTGIGYYYMDNFFLESFLNYGYIVGTAFVLIALSPM
                     IYALLQRSSSHRFRMLFLALAFSYTVNALFEGYAPFGPGAKSFILWLVFGCLLNTRIG
                     KVGEHSETS"
     gene            7421..8890
                     /locus_tag="VVR21_001936"
     CDS             7421..8890
                     /locus_tag="VVR21_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEU6055731.1"
                     /translation="MNILKQVSLKWNYVFNLANKLFSLTIPLIVTPYVTRVFSSDHFG
                     IYTYTNTVASYFVTFTLMGISMYGSKKISLKRHDEIAVNDEYASLLTVQLLNVGLATL
                     TYFLYVTFFVNNNQVIYWIQMLYVISAGFDMTWFLSGLERFREIAVRNIIVNVLSALM
                     IFFFVHTEADLAIYTLIKVGTIFISQIVIFLPVVRMQRFYLAGAEHIRRTYRGLLLLF
                     IPVLADTLFQTMDKIMLGIYASYTAVGLYYSSRMVTDIPQTVITSLNIILFPRITHLL
                     SQNKKVESNKLFYQSFILIIALSLATAFGVSAIARDFVGIFFGSSYGAVADYVPSLSL
                     YICLAAWSGTIRYQYLIPHSLERVYVVAIILGSGINLVLNSLLIPFLGVYGSILATII
                     SELVICVYQTYPIRKEIPLKGLLGYVIIFAGLSFLMYLSLGWLRLLLLGRLSTVLLLA
                     SEIIFGILVFTIATITYIYLGNPILWQAIKKYIESRKNV"
     gene            8887..9768
                     /locus_tag="VVR21_001937"
     CDS             8887..9768
                     /locus_tag="VVR21_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU6055732.1"
                     /translation="MISIIMPAYNEEKNIGAAIASIQQQTYTDFQLIIVNDGSTDDTA
                     AIVQEKIMGDERIVFLNPGKIGKVPAYNLASQYVKGDWIYFMGADDQLPLDAFEKWNK
                     EAQKWNPAEKVALRARMRMVSDSHKYDGLVLPKKNTVRNFSGPLTLLSKEMHRFILPI
                     PEAYPNEDIWWGLCIEYFGDRVSLIEDVVVYYRVHEGNSISRTSTFEPFNEKYHIRQI
                     IRRDFLERFSNHLTADQKTKLQRELKLEEARYKGNRLPILLMPGISAVHRLRLLFLSG
                     RRSYVLKVKLDRFFLGH"
BASE COUNT         3000 a         1499 c         1988 g         3301 t
ORIGIN      
        1 aaactagagt agtacacctc tgcttctaaa aaatttttag aaatcgattt aactgtcctg
       61 atcgatttgt catgttctta tttcatttta ctatattttt gtttcgcggg aagtctacta
      121 agatacttaa agatgcagat agtaaaaaaa tgtagacatt accgtaaaaa agtgatataa
      181 tcgtatgatg ttcaaggtat aggtgttaat catgagtaga cattttaaaa aatcacgttc
      241 acagaaagtg aagcgaagtg ttaatatcgt tttgctgact atttatttat tgttagtttg
      301 ttttttattg ttcttaatct ttaagtacaa tatccttgct tttagatatc ttaacctagt
      361 ggtaactgcg ttagtcctac tagttgcctt ggtagggcta ctcttgatta tctataaaaa
      421 agctgaaaag tttactattt ttctgttggt gttctctatc cttgtcagct ctgtgtcgct
      481 ctttgcagta cagcagtttg ttggactgac caatcgttta aatgcgactt ctaattactc
      541 agaatattca atcagtgtcg ctgttttagc agatagtgat atcgaaaatg ttacgcaact
      601 gacgagtgtg acagcaccga ctgggactga taatgaaaat attcaaaaac tactagctga
      661 tattaagtca agtcagaata ccgatttgac ggtcgaccag agttcgtctt acttggcagc
      721 ttacaagagt ttgattgcag gggagactaa ggccattgtc ttaaatagtg tctttgaaaa
      781 tatcatcgag tcagagtatc cagactacgc atcgaagata aaaaagattt ataccaaggg
      841 attcactaaa aaagtagaag ctcctaagac gtctaagaat cagtctttca atatctatgt
      901 tagtggaatt gacacctatg gccctattag ttcggtgtcg cgatcagatg tcaatatcct
      961 gatgactgtc aatcgagata ccaagaaaat cctcttgacc acaacgccac gtgatgccta
     1021 tgtaccaatc gcagatggtg gaaataatca aaaagataaa ttaacccatg cgggcattta
     1081 tggagttgat tcgtccattc acaccttaga aaatctctat ggagtggata tcaattacta
     1141 tgtgcgattg aacttcactt ctttcttgaa aatgattgac ttattgggag gggtagatgt
     1201 tcataatgat caagagtttt cagctctaca tgggaagttc catttcccag tagggaatgt
     1261 ccatctagac tctgagcagg ctctaggttt tgtacgtgaa cgctactcac tagccgatgg
     1321 agaccgtgac cgtggtcgca accaacaaaa ggtgattgtg gctatccttc aaaaattaac
     1381 gtcaaccgaa gcactgaaaa attatagtac gatcattaat agcttgcaag attctatcca
     1441 aacaaatatg ccacttgaga ctatgataaa tttggtcaat gctcagttag aaagtggagg
     1501 gaattataaa gtaaattctc aagatttaaa agggacaggt cggacggatc ttccttctta
     1561 tgcaatgcca gacagtaacc tctatgtgtt ggaaatagat gatagtagtt tagctgtagt
     1621 taaagcagct atacaggatg tgatggaggg tagatgaaat gatagacatc cattcgcata
     1681 tcgtttttga tgtagatgac ggtcccaagt caagagagga aagcaaggct ctcttggcag
     1741 aatcctacag gcaaggggta cgaatcattg tctctacctc tcaccgtcgc aagggcatgt
     1801 ttgaaactcc ggaagagaag atagcagaaa actttcttca ggttcgggaa atagctaagg
     1861 aagtggcgag tgacttggtc attgcttatg gcgcagagat atactatact ctggatgctc
     1921 tagaaaagct agaaaaaaaa gaaattccta cccttaatga tagtcgttat gctttgattg
     1981 agtttagcat gcatacttcc tatcgtcaga ttcatacggg attgagcaat attttgatgt
     2041 tgggaatcac gccagtaatt gctcatattg aacggtatga tgctttagag aataacgaaa
     2101 aacgtgttcg tgaactgatt gatatgggat gctatactca gataaatagt tatcatgttt
     2161 taaaacctaa gttctttggt gaaaaatata aattcatgaa aaagagagct cggtattttt
     2221 tggaacgtga tttagttcat gtagttgcaa gtgacatgca caatttagac agtagacctc
     2281 catatatgca acaggcatat gatatcattg ctaagaaata tggagcgaaa aaagcgaaag
     2341 aactttttgt agataatccc agaaaaatta taatggatca attaatttag gagaaaatat
     2401 ggagaaacaa aacactttgg aaatcgatgt attgcaacta ttcagatctt tatggaaaag
     2461 aaagttggtc attttattag tggcaattat aacttcttca gttgcttttg cctacagtac
     2521 ttttgttatc aaacctgagt ttactagtac gactcggatt tatgtagtta gccgtgatca
     2581 gggagagaag tctggtttaa ccaatcaaga cttgcaggca ggatcgtact tgactaaaga
     2641 ctatcgtgaa attatcctat cgcaggatgt tttggaggaa gttgtttctg atttgaaact
     2701 agatttgacg ccaaaaggtt tggctaataa aattaaagtg gcagtaccag ttgatacccg
     2761 tatcgtgtct atttcggtta atgatcaagt tcctgaaggg gcaagccgta tcgctaactc
     2821 tttgagagaa gtggcggctc aaaaaattat cagtattact cgtgtttctg atgtgacaac
     2881 actggaggag gcaagaccag cgatatcacc gtcttcgcca aatattaaac tcaatacact
     2941 aattggtttt ttggtaggat tgattgtcat aaatgttaca gttcttcttc ttgaactttt
     3001 ggacacacga gtgaaacgtc cggaagatat cgaagatgca ctacagatga cacttttggg
     3061 ggttgtacca aacttggata agttgaaata ggagagagag atgccgacat tagaaatagt
     3121 acaaaaaaaa ctggagttca ttaagaagac agaggaatat tacaatgcct tgtgtacaaa
     3181 catacagttg agcggagata aactaaaagt gatttccgtt acttctgtta accctggaga
     3241 agggaaaaca actacttcta taaatatagc atggtctttt gcgcgtgcag gatataaaac
     3301 tcttttgata gatggcgata tccgaaattc ggtgatgtca ggagttttta aatctcgtga
     3361 aaaaattaca ggcttaacag aatttttatc tggtacaact gatttatctc acggtttatg
     3421 tgatacaaat attgaaaatt tatttgtagt tcaatcggga gctgtatcac caaaccctac
     3481 agccttgtta caaagtaaaa attttaatga tatgattgaa accttgcgta aatattttga
     3541 ttatatcatt gttgatacag cacctattgg agttgttatt gattcggcaa ttatcactca
     3601 aaagtgtgat gcgtctatct tggtaacggc aacgggtgag gtgaataaac gtgatgtccc
     3661 aaaagcgaaa caacaattag aacaaacagg gaaactattt ttaggtgtcg ttctcaataa
     3721 atttaatgtt caacatgaaa aatatggttc ttacggtaat tatggtaaaa gataaaatga
     3781 atatagtatg gaaggggcta caatataact ctggcattct gaactgcacc ccaaaagtta
     3841 gacagaaaaa atctaacttt tgggggtcag tacattctta cagggtacac ttgttagttt
     3901 attagcttag atactgattg caatttcaga aaccgatatt ttttcaaata aatattcggt
     3961 ctgtttggaa gtgcaatcga actgaacttt ccaatgcttt attgggcatc atatattacc
     4021 gaaacaaata aattttgtta tattggatga tgttgttatg ttattgtaaa aatattgtgt
     4081 gaccaaatat attgagtctt tgtggtctaa taggctgata tatttaattt gataaataaa
     4141 aataagatga agtttgaatt tagagtgaga gatagtttat gtatagtata ttaaaacggt
     4201 taggagatat atctatatct ttaatagtta taacgttatt ttgtccattt tttatcctaa
     4261 ttgcaattgc gattaagttt gattcaaaag gacctgtaat atttaaacaa aaacgttttg
     4321 gaattcacaa aaaaactttt tatgttttta aatttcggac tatgaaagtg gagacaccaa
     4381 aaaatgtggc aactcgagat ttacaaaatc cagagcagtg gatcactaga gtgggaactt
     4441 tcttaaggaa aacatctcta gatgaattgc ctcaattatg taatattctt gttggtgata
     4501 tgagtattgt aggaccaaga cctgcccttt ggaatcaatt tgatttgatt gaagaaagag
     4561 acaaatatgg agcaaatgat attttacctg gtttaacagg ttgggcacaa atcaatggtc
     4621 gtgataatct atcaatagat atgaaagctg aattggatgg atactatgtg acacataaat
     4681 cgttgctaat ggacattaga tgtatagtaa gaacaatacc ttatgtgctg aaacgcaaag
     4741 gaattgtaga gggaagtcaa aaagagagtt aagttgtacg atgaaaattt tatttgttag
     4801 tcaacattat agaccagaac cttttagatt atcagatatt tgtgaggatc ttgttgagag
     4861 aggtcatgaa gttactgttt tgacaggaat tcctaattat cctgaaggta aaacatatgc
     4921 ggattatcgg aataacaaaa atagacgaga gactatagaa ggagttactg tttttcgttc
     4981 ctatacaatt ccaaggggaa aaagtacttt acataggata ttaaattatt ttagttttgc
     5041 tatcagttcc tcgatagggg ttctactggg acagtataaa gcaaaagatg gatcagaatt
     5101 tgattgtatt tttgtaaatc aatcgtctcc agttatgatg gcatgggctg ctatggctta
     5161 taaaaataaa tataagaaac ctatgtttct gtattgtatg gatgtttggc cagatagttt
     5221 aactgtaggt ggagtgaaac aagatggctt gattttcaag ttgtttaaat ttatatcgaa
     5281 aaaagtttat cgagctagtg attatatatt tgttactagt ccatcattta agaattattt
     5341 tgtgaaccaa tttgacataa cagaacaaaa gattacttat ttgccacaat atgcagaaga
     5401 tctttttatc cctgatgaat ctagagttaa taaagaaagt gttgacctaa cttttgctgg
     5461 taatattggc aaagcacaaa atttggaaac tattttgaaa gctgccagtt tgatagagaa
     5521 gaataccgat ctacccaaga aaattcaatt tcattttgtt ggagatggta cggaattgct
     5581 aagtatgaaa gcattagctc atgaattgga gttaaagaat gtttccttct atggaagacg
     5641 ttctttggaa gaaatgccta ccttctataa aaaatcagat gctatgttag tttctttaat
     5701 aggagactcg atagtttctc gtactatacc tgggaaggta caatcttaca tggcggcagg
     5761 gaaaccaatt ataggtgcaa tttcaggaga tactaaaaca attgtagaag aagcaaagtg
     5821 tggttttgtc agtcctgaac aagatgtgga acaattggca caaaatattt gtaaatttag
     5881 tatgttgtct acggaagaac aaagagagtt aggaaagcaa gctcgttgtt actatgggaa
     5941 gcacttttct aaagagcagt ttatgacaca gttagaaaat tatttgagag agggattttc
     6001 ctcatgagaa ttttaatgat taatactgtt tgtggtatta ggagtataga tactttgtta
     6061 aagaaatttg ctgagatttg gcgtttcaat ttataggatt tgaaagttta gtaagtaaat
     6121 ttaagtattt tctgtaagat aataagttct taatgactta ttaactattg tataatagct
     6181 gtaattccaa ataaaagtac ataggtactg acatgttgac gatagtaagg aggaggaatg
     6241 gaatcccgaa agaaatttgt ttgttttccc aatagtagtt tgcgttttta tattttgcag
     6301 gcagcgattg ccttatctat tttatcgcag gctccctata tctggaagtt tagtgggata
     6361 cctacacaac ttctgattat gcctttgtgg atcctgttgg gagtagtgtc tattttttct
     6421 agaattgaca tggaacgatc attcctattt tttttattaa caataggttg tttaattagc
     6481 actattgctt tgttagatat agttacggga gtatcttatg tctttaatgg tttgtctcag
     6541 caactctatt tggctgtggg aattctagtt ttaggctact ggaatgctga tgtgattgtt
     6601 cattattgga aaatcatcac catgactttt ttgggagcat gtttgctgat ttcagtggat
     6661 atttattttc actactttca aggacatact ttttcaaata ttgattatgt ttatcgagct
     6721 aagaattcag cggcatctat ctttttatcg gcagttattc tcaacttgtc tctatataat
     6781 cgcaagtggg cactgtggag aaaagtattg ttattagcta gtagcggatt gctgatttac
     6841 atgtgcatcc ttatgcggtc acgagcagtt ctgttagcag ctgcagtact tccgctagtt
     6901 tatatatggt ttcaggagac gtctttgggg cataagattg gacggacatt aggagtttca
     6961 acagtagtag gtgcgttttt gctcaattca gctatttatg atttttttat caataatcta
     7021 tttttaaggg tcacatctga atatcgacca tctagtctga ctttggacta cgtttcctcc
     7081 aaccgttttg tgtattttga gatctttgct aaagaaattt caggacatga attaacaggg
     7141 attggttatt attatatgga taattttttt ctagagagtt ttctcaatta tggttatata
     7201 gtagggactg cttttgtttt aatagccttg tctcccatga tttatgccct cttgcaacgt
     7261 tcttcttctc atcgtttccg catgcttttt ttagcccttg ctttttctta tactgtcaat
     7321 gccttatttg aaggttacgc gccatttggt cctggtgcca agagttttat tctttggtta
     7381 gtttttggtt gccttctgaa tacacgaatt ggaaaggttg gtgaacattc tgaaacaagt
     7441 tagtctaaag tggaactatg tgtttaatct tgccaataaa ctattttctc taactattcc
     7501 acttattgtt actccctatg tcactcgagt cttttcttca gatcattttg ggatttatac
     7561 ttataccaat acagttgctt cttactttgt tacctttaca ttgatgggga taagtatgta
     7621 tggaagtaag aaaatttctc ttaaaagaca tgatgagata gcagtcaatg atgaatatgc
     7681 ttccttactg actgtccagc tgcttaatgt aggtctagcc acgttaactt actttctcta
     7741 tgtgaccttt tttgtcaata ataatcaagt tatttattgg atccagatgt tgtatgtgat
     7801 ttctgctggt tttgatatga cttggttttt atcaggattg gaacgttttc gtgaaattgc
     7861 tgttcgaaat atcattgtaa atgtcttatc agccctcatg atttttttct ttgtgcatac
     7921 ggaggctgat ttggctatct ataccttaat aaaggtaggg acgattttta tcagtcagat
     7981 tgttattttt ttaccagttg ttcggatgca acggttttat cttgcaggag ctgaacatat
     8041 tcgacgtacc tatcgaggct tgcttttgtt gtttatccct gttttggcag acaccctttt
     8101 tcaaactatg gataagatca tgctaggtat ctatgcatcc tatactgctg tgggtttgta
     8161 ttactcaagt aggatggtta ctgacatccc gcaaactgtc attacttctc tcaatataat
     8221 cttatttcca cgaataacac atcttttaag tcagaataaa aaagttgaat ctaataaact
     8281 tttttatcag tcttttatct taattattgc tttatctcta gctacagctt ttggagttag
     8341 tgctattgct agggattttg taggtatttt ttttggatct tcatatggtg cggtagcaga
     8401 ttatgtgcct agtttatcgc tctatatctg ccttgctgcc tggagtggaa cgatacgtta
     8461 ccaatatctg attcctcatt cacttgagag agtctatgta gtagcgatta ttttgggaag
     8521 tgggatcaat ctagttttaa actctctctt aattcctttt ttgggagtat acggttccat
     8581 tttagctact attatatcag aattagtgat ttgtgtttac cagacatatc ctattcgaaa
     8641 ggaaattcct cttaaaggat tgttaggata tgtgatcatt tttgcaggct tgtcttttct
     8701 tatgtatcta tctcttggtt ggctacgatt gttattgcta ggccgcctat ccacagtatt
     8761 gctattggca agtgaaataa tatttggtat ccttgttttt actatcgcaa ctataaccta
     8821 tatttatcta ggtaacccaa ttttatggca agctattaaa aaatatatag aaagtaggaa
     8881 aaacgtatga tctctatcat tatgccagct tataatgaag aaaaaaatat cggagcagct
     8941 attgccagta ttcaacagca aacctatacg gactttcagt tgattatcgt caatgatgga
     9001 tctacagatg atacggcagc tattgtacag gaaaaaatca tgggagatga gcgaattgtc
     9061 tttttgaatc ctggaaagat tggcaaggta ccagcttata acttggcttc acagtatgta
     9121 aaaggagact ggatatattt tatgggagcg gatgaccagt tgccattgga tgcctttgaa
     9181 aagtggaaca aggaggctca aaagtggaat cctgctgaaa aggtggcttt aagagctcgc
     9241 atgcggatgg tttctgactc tcacaagtat gatggattgg tattaccaaa gaaaaataca
     9301 gttcgcaatt ttagtggacc tcttaccttg ctttcaaaag agatgcaccg ttttatcctt
     9361 cctatacctg aggcctatcc gaacgaagat atttggtggg ggctatgtat tgagtatttc
     9421 ggagatcgtg tttcgttgat tgaggatgtt gtggtttatt atcgtgttca tgaggggaat
     9481 tctatatccc gaacctcaac ttttgaacct tttaacgaga aatatcatat ccgtcagatt
     9541 atccgtcgtg attttttaga gagatttagc aatcacttaa cagcagacca gaagactaaa
     9601 cttcagcgtg aattgaaact agaagaagca cgctataaag gaaatagatt gccaattctt
     9661 ctgatgccag gtatttctgc agtacacaga cttcgattac tttttttatc gggtaggcgt
     9721 tcatatgtac ttaaagtcaa attggatcgc tttttcttag gacattagaa agaaggaaga
     9781 gatgtcaa
//
LOCUS       DAVHSI010000060         9673 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.061, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000060 DAVHSI010000000
VERSION     DAVHSI010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.061"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            71..820
                     /gene="truA"
                     /locus_tag="VVR21_001938"
     CDS             71..820
                     /gene="truA"
                     /locus_tag="VVR21_001938"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU6055733.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            810..1565
                     /locus_tag="VVR21_001939"
     CDS             810..1565
                     /locus_tag="VVR21_001939"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU6055734.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGIPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRTI"
     gene            1562..2023
                     /locus_tag="VVR21_001940"
     CDS             1562..2023
                     /locus_tag="VVR21_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6055735.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
     gene            2277..3548
                     /locus_tag="VVR21_001941"
                     /pseudo
     CDS             2277..3548
                     /locus_tag="VVR21_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(3676..3879)
                     /locus_tag="VVR21_001942"
     CDS             complement(3676..3879)
                     /locus_tag="VVR21_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055736.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCSNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(3872..4954)
                     /locus_tag="VVR21_001943"
     CDS             complement(3872..4954)
                     /locus_tag="VVR21_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU6055737.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPLQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(5080..5862)
                     /locus_tag="VVR21_001944"
     CDS             complement(5080..5862)
                     /locus_tag="VVR21_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU6055738.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(5862..7205)
                     /locus_tag="VVR21_001945"
     CDS             complement(5862..7205)
                     /locus_tag="VVR21_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU6055739.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(7304..8620)
                     /locus_tag="VVR21_001946"
     CDS             complement(7304..8620)
                     /locus_tag="VVR21_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU6055740.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            8813..>9673
                     /locus_tag="VVR21_001947"
     CDS             8813..>9673
                     /locus_tag="VVR21_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU6055741.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLT"
BASE COUNT         2821 a         1860 c         2126 g         2866 t
ORIGIN      
        1 atttttatac ccatacaata tttgttttag gtccttgttt acagactaat ttcttgataa
       61 aatagaggtt atgacgagat ataaagcaac tatttcctat gatggttatg cctttgctgg
      121 ctttcagcgc cagcctcatg cgcgtagcgt tcaggaagaa attgaaaaaa ccttgaccag
      181 attaaataaa gggcaagcca ttactgttca cggtgctggt aggacagata gtggggttca
      241 tgccctggga caggtcattc attttgacct gccttatcag atggatgagg agaaactccg
      301 ttttgccttg gatacccagt ctcctgaaga tattgatgtg atttcgattg agcttgtggc
      361 agatgatttt cattgccgtt atgccaagca tagcaagacc tatgagttta ctgtggatag
      421 aggacgtccc aaaaatccga tgcgccgtca ctatgccacc cactttccct acccactcga
      481 tgtggaacga atgcagattg caatcaaaaa gctagaggga acccatgatt ttaccggttt
      541 tacagcctct gggactagtg tagaggataa ggttcgcacc atcacagaag ctagtttaat
      601 agtcgatgag acaggacaat ttttgacctt taccttttcc ggaaatggtt tcttgtataa
      661 acagattcgc aatatggtgg ggactcttct caaaatcggt aacaaccgca tgccagtaga
      721 gcagattgat ctcatcttgg agaagaagga caggcaactt gcaggtccca ctgcagcacc
      781 aaatggtttg tatttaaagg agattcgtta tgaagaataa tcgtatttta gcactttctg
      841 gaaatgatat ttttagtggt ggtggactgt cagctgattt ggctacctat accttgaacg
      901 gcttgcatgg gtttgtagca gtgacttgtt tgacagcctt gacagaaaaa ggatttgaag
      961 tctttccaac tgatgatacc atttttcaac atgaattaga tagcttgcgt gatgtggaat
     1021 ttgggggaat taagattggt cttctcccta ctgtcagtgt ggctgagaag gccttggatt
     1081 ttatcaaaca acgcccagga atacctgtgg tgttggatcc tgtcttggtc tgcaaggaaa
     1141 cgcatgatgt agctgtcagt gagctctgcc aagagttgat tcgctttttc ccttatgtca
     1201 gtgtgattac gcctaatctc ccagaagcag aattattatc cggtcaggaa attaaaacct
     1261 tggaagacat gaaaactgca gcgcagaaat tgcatgattt aggagcgcca gcagtcatta
     1321 tcaagggagg caatcgtctt agtcaggaca aggctgtgga tgtcttttat gatggacaga
     1381 cctttactat cctagaaaat ccagttatcc aaggccaaaa tgctggtgca ggttgtacct
     1441 ttgcctctag cattgccagt cacttggtta aaggtgataa acttttgcca gccgtagaaa
     1501 gctctaaggc tttcgtttat cgtgctattg cacaagcaga tcagtatgga gtaagaacaa
     1561 tatgaagcaa acaaaaacaa ctaaaattgc ccttgtatcc ctattaaccg ccctttctgt
     1621 ggttctaggt tatttcttaa aaatcccaac acctacagga attctaactc ttttagatgc
     1681 tggtgtcttc tttgcggcct tttactttgg tagtcgtgaa ggagcggtag tcggaggact
     1741 agcaagtttc ttgcttgacc tcttatcagg ctaccctcag tggatgttct ttagcttggt
     1801 caaccatggc ttgcagggat ttttcgcagg atttaaagga aaaagtcagt ggttaggcct
     1861 tattttagca actattgcca tggtaggggg ctacgccttg ggttctactt tgatgaatgg
     1921 ctgggcagca gccctcccag aaattctacc aaattttatg caaaatatgg cagggatgat
     1981 tgtaggattt attcttagtc aaagtatcaa gaagattaag taatactctt cgaaaatctc
     2041 ttcaaaccac gtcggcttcc atctgcaacc tcaaaacact gttttgagca gcctgcggct
     2101 agctttctag tttgcacttt gattttcatt gagtataaaa agatcttggg aaaagactca
     2161 atttcagtag aaaaggaagt aaatcttccc acattaaaac gcatattacc aaggttctta
     2221 tgaactgcac cccaaaagtt agacagaaaa aatctaactt ttggggtgtt tttattatga
     2281 aattgagttg tgatgataaa gttcagatct atgaacttag aaaacaagga tatagcttag
     2341 agaagctttc aaataaattt gggataaaca attctaatct taggtacatg attaaattga
     2401 ttgatcgtta cggaatagag ttcgtcaaaa aagggaaaaa tcgttactat tctcctgatt
     2461 taaaacaaga aatgattaat aaagtctgac atgaaggctg gactaaagat agagtttctc
     2521 ttgaatactg cctcccaagt cgtacgatac ttcttaactg gctagcacaa tacaggaaaa
     2581 acgggtatac tattgttgag aaaacaagag agagagtacc tgagagcgga gaatgccatc
     2641 ctaaaaaagt taagagaact ccgattgaag gaggaaaaag agaaagaaga aagacagaaa
     2701 ttgttcaaga attaatgact gagttttcgt tagttcttct tctaaaagcc attaaactag
     2761 ctcgttcgac ctactactat cacttgaaac agctagacaa aacagataag gaccaagagc
     2821 ttaaagctga aattcaatcc atttttatcg aacacaaggg aaattatgct tatcgtcggg
     2881 ttcatttaga actaagaaat cgtggttatc tggtaaatca taaaagagtt caaggcttga
     2941 tgaaagtact caatttacaa gctaaaatgc gacagaaacg aaaatattct tctcataaag
     3001 gagacgttgg taagaaagca gagaatctca ttcaaggcca atttgaaggc tctaaaacaa
     3061 tggaaaagtg ctatacagat gtgacagaat ttgccattcc agcaagtact caaaagcttt
     3121 acttatcacc agttttagat ggctttaata gcgaaattat cgcctgtaat ctttcaactt
     3181 cacccaactt agaacaagta caaacaatgt tggaacaggc attcacagag aagcactacg
     3241 agaatacgat tctccatagt gaccaaggct ggcaatatca acacgattct tatcatcagt
     3301 ttcttgaggg taagggaatt caagcatcca tgtcacgcaa gggaaacagc caagacaacg
     3361 gtatgatgga gtccttcttt gggattctga aatcggaaat gttttatggc tatgagaaaa
     3421 catttaaatc acttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
     3481 ataaacgaat taaggtaaaa ctaaaaggac ttatccctgt gcaatacaga actaaatcct
     3541 tcggataaat taattgtcta actttttggg gggcagttca ttctacaccc actattatgc
     3601 gttttattgt gggaagattt tcctcatttt ctagtgaaat tgaacttttt ctaacatctt
     3661 ttgatagatg acttcttaat caattatcat ttccattgtt gtttcttggg gtttcatccc
     3721 ttgtctttga taaaagcgga gagcaccctc gttatcattc cagacactta gggttagatt
     3781 actgcagcca atttctttag cataatagca gaaaaatgac aataaaatag cccctagata
     3841 ttttgaaagg aaagcatagg ggctatatag tttaatcaaa ataaagcaaa tctttgctgg
     3901 tgcttgtaaa gaggtcgaag ccatccttgg taacaacacc gcagtcttca atacgaacac
     3961 cgactttacc agggatatag atacctggtt caacagagaa gcacatgcct tcttcgatga
     4021 ccatgtcgtt tccttccatg atagatggga attcatggac atccataccg ataccatgcc
     4081 cgagacggtg gttgaagtac tcaccataac cagctttttc gatgacctca cgggcagcgc
     4141 ggtccacttc atgagcagtc acacctggct tgataaagtc aagagcagct tgttgggctt
     4201 caagagtcaa gttgtaaata tctttcttga attggtctgg tttgccgaca gcgactgtac
     4261 gagtcatatc tgacgcatag ccattgacca gaacacccag gtcaaagagg agaagagcat
     4321 cattttcaac cttattagct gctggaatgc cgtgtggatt cgcagcatta tcaccagtca
     4381 agaccatggt atcaaagctc atttcataac cttcacgttt catggcaaag tcgatttgtg
     4441 cgatgatatc tgtctcagtc ttatcaagag aaatattgtc aaaaccaaca tgaacagcct
     4501 tgtcagcata aagacctgca accatcattt tttgcacttc atcagctgat ttgatgaggc
     4561 gcatgcgttg gatacgagga gtgaggttgt caaactcagc agtctcaaaa actgttttca
     4621 aaccatggta tttggtcaag atgagattgt caaactcaac agcgacacgt ttgaagtcaa
     4681 gttgtggaag agcatgtttg attttttgca atggattttc agaatcgaca tagcccacta
     4741 ctgggaagga aacggtgcta cttgcacgtt ctacttcaag agctgggaca aagaggagag
     4801 gttcctgatc cgctaggaca aagaggaaca tttggcgttc atggggatca ctgtaaaaac
     4861 cagtgaggta attgattgtg acggggtcag atacgacagc gacgtctagt ttttctgatt
     4921 caagatatgt taggatttgt tgtaatttag acatatgcta ccttctttct acccctctat
     4981 tttggcaaaa aatgagagaa aatgcaaggg agaagggtaa aagaaaagac aaaaaactcc
     5041 gacaagataa cggagttctt tgatatcatt ttcctttgtt taagaaaagt cagccttgct
     5101 tttgacgtca ctgtactctt cagcgatttc ttggctgaga atgtcctcat aggcagggag
     5161 ttggatgtcc tgaccatatt tcttcttgag ggcagtagta actaggcgat aagccagatt
     5221 ggcattacga gagaggatag gcccgtggaa gtaggaacca aagacattct tataatgaac
     5281 cccttcaccg accttttctt cgttgtttcc atttccatag acaacctgtc ccagcggttt
     5341 ttggtcatca gagaggaagg tacgaccttg gtgattttca aatccatagt aggtttcatc
     5401 gaaatcttca ttgtgaatct tgatgtcacc gataaaacgg ttattggtct ggttgagcgt
     5461 gtagtgtccc atgaccccta gcccttcgat acgttttcct gaagcttcaa cataatattg
     5521 acccaatagt tggaaaccac cgcagatagc cagaactaca ccgtcgtttt ggatgtagtt
     5581 gtcaatgctc tcttttttag caggtaggtc gtctgcaatg atactttgtt caaagtcttg
     5641 accaccaccg aaaaaggcga tgtcgtagtg attttcatca aagtcatcat ggagagaaac
     5701 gatgtcaacg gtcacatggg ctcccagttt ttcagccaca tacttgagca tgaggatgtt
     5761 tccattgtcc ccgtaggtat tcatgagatt tccgtagagg tgggcaatgt tgagctgata
     5821 ggggtaattg ctatcttttg aggaaagtga agtataaacc attagttcat ctcctttcta
     5881 acaatctgac gactagccag cagttcacga aattccagca tggcagtata agttgccaga
     5941 atataggcat gcttgcagtc ttgattctca atggtcttga gaacttgctc cagattactc
     6001 gtttcagtga ttttctcagc tggatagcca gtcactcgga ggcgacgagc gatttcagaa
     6061 tgacgaacac cgccagcgtt gatttcagga atgtccatgt cagtgatttg ctcaaagtct
     6121 gcatcccaga tccagctagt gtcaattcca tctgcatagt tggcattaag gaggacagat
     6181 aggctaaatg gataaggtgc tagtttgatc atttcgatag cttgggttgc accgactgga
     6241 tttttaatca agacaagggt acattccttg tcaccgatat gaaaggtttc ttggcgtcca
     6301 aagacagcac ggctcttgtc aaatccctgt ttgatgagtt gggaatctgc gccgaggaaa
     6361 cgggcgatgg ccacagcagc tagggcgtta tagatattat agagcccgcc gatttggata
     6421 ccgtattctt ggccgtctat gacaaagcga gagcgattgt tggtcaactc aaccagtttt
     6481 gtcaaacgat agtcgagatc aggacgttta catccacaac cttcacagat ataggcaccc
     6541 aagtttgcat aggtattatg ctcatatttg aggatgcctt ggcagtcagg acagagaatc
     6601 ccttcggtat tgtagtgagc cagttgggct ggtccttttt ccaagtcaaa accaaaatac
     6661 tctatagggt ttggaatagt tggcttgtag aaaagtggac tgtctccgtt aaggagaaca
     6721 gtagcagttg gaacttttcg aatggcatcc aatatcatgt tataggtagt atagatttca
     6781 ccgaaacggt ccatctggtc acggaaaata ttagtaataa caaataagct tggctggata
     6841 tagtcacaga tacgagatag actggcctcg tcgatttcta ggacggcaat atttttccca
     6901 gttttagaag atttggctgt taagaaggtt gtcgcaattc ctgtaatcat gttggcaccg
     6961 cttgggttgg tcagaacttg accataaact tcttttaaaa taccgacagt gagggcagtt
     7021 gtcaaggttt ttccgttggt tccagtgacc acgacaatct cgtagttctt agctaggttt
     7081 tgtaaaatat ctttatcaaa ttgaagggcg actttacctg ggagcgtact tccacggcca
     7141 agacggctta aaatgaagtg ggaagaacgc ccagcaagaa ggcccaaagt agtttttaag
     7201 ttcatgtttc tattatatca taaaagagga gaaagacaga tttgagattc cgcagaagta
     7261 aaaacagccc aaagagggct gttcgatacg attaaatctc aacttaaatc gcaaacaagt
     7321 cattcaagtt ctcagccaag gttgggtgag tgaagatttg ttttgtgaag taagtgtaag
     7381 gaatcttgtt gtccatagca acagtgatga tgttgatgat ttcttgagaa ccttctgaga
     7441 agatgcttgc accaagaatt tcttttgttt cagtattaac aacagctttg aaagctccgc
     7501 gaaggtctcc atttacgtga ccacgaggca tggctgcaac agggatttct ttcactgcgt
     7561 atggaagttt caaatcagct gcttggcttt cagtcaaacc aacttgtgaa agtgcaggtg
     7621 tgatgaacat agtatttggc acattgagac ggtcctcaag tgtgtagctg ccatctccag
     7681 caaggtagct gtaaacaaca cggaagtcat caagtgaaat gtaagtaaat tgaagaccac
     7741 cgttgacatc tccaactgca aagacaccag gaacgtttgt ttgacagtgt ttatctactt
     7801 taatagcgcc acgttcagtt agttcaatat ctgtattttc aagttgaagt ggttctacat
     7861 ttggtttgcg tccagttgcg tagagaaggg cgtcgaaacg gtaagtttcg tcttcagtta
     7921 cgacaagcac ttggtcaccg tcgtttttaa tttcagtagt atggatattt tgaagcaatt
     7981 caataccgtc ttcttccatg tattgtttag caagagctgc gatggaaggt tctgcacgag
     8041 gtaggaatgt atccaaggca tctaggactg taaccttgct tcctagttta ttgtaaaggc
     8101 cagcaaattc aagaccgata tttccgccac caaggactcc aagtttttca ggcaatttat
     8161 ccaagctttg gatacctgtt gagtcaaaga tgtttttgct tgtagcaagt ccaggaattg
     8221 gcaagacgtt tgaaacagca ccagtgttga tgacgattgt ttcagcagtc agttctttct
     8281 tttcatcacc agcttggatt tcgatgactt tatttgaaag gaagtgagct tccgcatcaa
     8341 agatatctac gcctgtacca gcaacagtcg catagttttt accgttgagg cgaccagtga
     8401 tcgtgttttt agtagcaatc acttcttcaa aagacaagtc cttttcagca gcaactagca
     8461 aggttttagt tgggatacaa ccaatgttga tacaagttcc accgtacata gccttgctgc
     8521 gttcaacgag ggcaactttt ttgccagctg aagccaattt acctgctagt gttttaccag
     8581 ctttaccaaa tccaataaca attaaatcgt atgttaacat ttatcttcct cctattcgaa
     8641 tttcattcta gcacaagaaa aaaacttttg cacaattctg ctacggaaaa gacagaaaaa
     8701 gataaaaacg ctttccagac aaaaaactag taattttttg acaagcttga taaactaaaa
     8761 tcctatctat ttttatataa gaaagaataa atgttcgaaa ataggaggtt ttatgaaatc
     8821 gaatcgttat attattgcct ttgctggggt cattttacac ttaatgctgg gttcgactta
     8881 tgcttggagt gtttatcgta accctattat tgaaaaaacg ggatgggatc aggcttctgt
     8941 tgccttcgcc tttagtctag caatcttttg tttgggctta tcggctgcat ttatggggcg
     9001 tttggtagaa aaatttggtc cgaaagtcat ggggagtcta tctgcttttc tatacgcagg
     9061 tggaaatatc ttaacaggat ttgcaataga ccgtcaggaa ctgtggttgt tgtatctagc
     9121 ttatggcatt ttaggtgggc ttggtttggg agcaggctat attacccctg tgtcaacgat
     9181 tataaaatgg tttcctgata aacgtggtct cgcaacaggt ttagcgatta tggggtttgg
     9241 ttttgcttct ttattgacta gtcccatagc gcaacacctc atcgcagggg tagggattgt
     9301 agaaactttt tatattttag gagcaagtta ctttattatc atgctcctag cttcacaatt
     9361 cattaagcgt ccaaatgagc aagagcttgc aattttatct tcttcaggga aagaaaaaac
     9421 agcctctttg acgcaaggaa tggctgcaaa tcaggctcta aaaagcaatc ggttttatat
     9481 gctttggatt attttcttta tcaacatagc ttgtggttta ggcttaattt cagcggcatc
     9541 gccaatggca caggagatgg ctggcttgtc tacaagtcat gcagcagtaa tggtgggtgt
     9601 tttggggatt ttcaatggat ttggtcgctt gctctgggcg agtttgtctg actatatcgg
     9661 tcgccctcta acc
//
LOCUS       DAVHSI010000061         9651 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.062, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000061 DAVHSI010000000
VERSION     DAVHSI010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.062"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            190..285
                     /locus_tag="VVR21_001948"
                     /pseudo
     CDS             190..285
                     /locus_tag="VVR21_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(538..1158)
                     /locus_tag="VVR21_001949"
     CDS             complement(538..1158)
                     /locus_tag="VVR21_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU6055742.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1158..1640)
                     /locus_tag="VVR21_001950"
     CDS             complement(1158..1640)
                     /locus_tag="VVR21_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU6055743.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1640..2482)
                     /locus_tag="VVR21_001951"
     CDS             complement(1640..2482)
                     /locus_tag="VVR21_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU6055744.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVDYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2577..3377)
                     /locus_tag="VVR21_001952"
     CDS             complement(2577..3377)
                     /locus_tag="VVR21_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU6055745.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3521..4900
                     /gene="glmU"
                     /locus_tag="VVR21_001953"
     CDS             3521..4900
                     /gene="glmU"
                     /locus_tag="VVR21_001953"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU6055746.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRSRQINKDEYAT
                     RLPHHPKNQ"
     gene            4910..5455
                     /locus_tag="VVR21_001954"
     CDS             4910..5455
                     /locus_tag="VVR21_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU6055747.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5467..5781
                     /locus_tag="VVR21_001955"
     CDS             5467..5781
                     /locus_tag="VVR21_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU6055748.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5798..6490
                     /locus_tag="VVR21_001956"
     CDS             5798..6490
                     /locus_tag="VVR21_001956"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU6055749.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6567..7058
                     /gene="rocS"
                     /locus_tag="VVR21_001957"
     CDS             6567..7058
                     /gene="rocS"
                     /locus_tag="VVR21_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU6055750.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7156..7746
                     /locus_tag="VVR21_001958"
     CDS             7156..7746
                     /locus_tag="VVR21_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU6055751.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7755..9518
                     /locus_tag="VVR21_001959"
     CDS             7755..9518
                     /locus_tag="VVR21_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU6055752.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         2982 a         1675 c         2062 g         2932 t
ORIGIN      
        1 aagacttttt gaccagcctc atttttttaa cttgatactc agtgaaaagc aaagattaaa
       61 ctaggaagct agctgtaggc tgctcaaaga acagctttga ggttgcagat aaaacttgtg
      121 aggtaaccaa catatataat gtgaagctga cgtggtttga atagatttta gaagggtatg
      181 agtctggaag ttttaatgga taatgcaaga ttccatagaa tgggtaagct agagttctta
      241 tgtgaagagt ttgggcataa acttttacct tttcctccct actcatctta gtatagaaaa
      301 gtgaatctaa aatagtacat aactgcttct aaaacattct tataaattga tttaaattct
      361 caaatcatat tattcagttc ttatttcatt ttgctctaca atcctgttga gaagacacgt
      421 gttcatatca aaaaggtatt ggcaagttgc aatacctttt tacaaggttc ttttgtctta
      481 tttttgtttc aactgactat atctcctatg gttctagttc agaaggctag gctataatta
      541 tgattgataa gaagtatcat tccaagtatt gagagtgaat gtttcaaaat catgggtttc
      601 tataatggtc aggctggcat ttgctagacc gccatcttta cgaagaagtg gttctttata
      661 gcctaggaga gtacgaagac tggcagtaag attggcgccg tgtccgacaa ttagaatacg
      721 ctcagctgga ctatctttta atgatttgat aaattggatg gtccgctgag ttgtactata
      781 gagggattcg gctccgaaca ttcgagtgtc aaattgagca agatttgaac gaaaagcctg
      841 gatttgttgc gggtaaatag cttccagggt tgcaattttc aaaccttcta acttcccaag
      901 ttgccattca cggagattag gaacgatttc taaagaacag ggggtatgga gttgactttg
      961 gataatctca gcagatttga ccgctcgagg taaatcactt gaataaatct gatcaaaagg
     1021 aatttccttg agatactggc caagtcgttt tagggtttca atggattcag gaagaagagg
     1081 agaatcaccg ctagcacctt gaaaacgacc ttcttggttc cagagggtac gaccgtggcg
     1141 gacaaagtag agtttcatta cttgatgtcc tccaaaatat ctacaaagtc tgcctttaca
     1201 aagctagcca agtcttgtgg cgcgacgata atgctgtgtc cgacttcgcc tgcagagaca
     1261 atcattcgat ccaaatctag agcaatttta tcgataaaaa tgggataatt gtgtttctga
     1321 cgaattccga caggattatt ggctccatga atgtaaccag ttgttttttc taagtccttt
     1381 tgtggaatca tgctcacttt tttattgcca gaaattttag ctagtttctt ttcagacaag
     1441 tgctgagtga tagggacaat tccgataatc ggtccggtct tgtctcccaa aagcgccaag
     1501 gttttgaaaa tctgatctcg ttcataacct tgaggaagct ctccttctag ggcattgatt
     1561 tgaatcccct gatgagggat agctgcttta gataggattt gttccaccaa tgtttttttg
     1621 attttaactt tttttgccat tatttatatt tatcctccaa ttgactcatc caaataccaa
     1681 gccagattcc cagcgcaaag aagaaggcga tgatgacata atcgacaagt gaaagtcctg
     1741 tgtattggat actttcagcg tttcctgcat ttggaattaa gatcaaaagg gtacttgata
     1801 ggacgatacc gatgatgaaa tgatagacgc gtgagtggta gttgtttaag gcataatcca
     1861 tcaattttga aaaaacgatg agagttgcac ctgcaccaat tccaatcgga aagaaggttc
     1921 ccaagaaatc aaaagtttta aaaccagtca acataggagc atagagtccc aaaatcaaaa
     1981 gtaaatttga tgggctgagg ccaggaacca agacgccaag ggccaatagt gcgcctgcta
     2041 ggacgaagtt aagaaagctg gcgcttaagg ttccaacgac aaaatttaag gcatagagtc
     2101 ctaatccaga aatgataaag gttgtccata accaagctaa atcaatcttg tctcggtcag
     2161 attctcgagt tgattctttg aggaggctag gaactgtacc gataatagct cccgcaaagc
     2221 tccataatac aaaaacctga taattttcaa gcaggtattc aatcgggtag gaaaataagc
     2281 cgattcccag aagcataccg atggcaactg gaataaagta caaaacattt tctttaaagt
     2341 ctttaaaggg atgggccaga aagccaatca ttcgttcata gattcctaag attgctgcta
     2401 gaacccctcc ggaaattccc ggtaggataa atccaagagc aattacaatc cctttaataa
     2461 cgcgtgctaa ccatgagagc atatatttcc tccaactatt tctatttcaa aaaatcctta
     2521 ctatattgta tcacaatcag acacaaaaag aaaaagcaaa tgataaacaa atgcttttaa
     2581 ggttttaaaa aaagttttcg aaaggtttct tctttatttt ttaagggaga gataacgttg
     2641 atatctaaat cgtggtcaaa gccggcaatt tttcctttag atgtgtattg gtgaatatca
     2701 taatctaaat cagttttagg actgctctcc aaaaatcctg agtctgagcc gtaggacgga
     2761 atccaaacag aggtaaactt gcctgtatca atactgtgtt cttccatgaa gtagacacca
     2821 acgtagatgc cgatgttttt agcacctagt gatgctagtt ttgctcgaaa gttttcgaca
     2881 ccttcgttca tattagacat ggttttgtct tccacgtcaa gccaatagta actagggctg
     2941 taaggagagg cagcattgta gaaaacttcg gcagcctttt ccatttcttg gacacttttt
     3001 ccagctacat aagcgtagac agcaactggg acattccgct tttgaagttc agtgatatga
     3061 ctcttatagg ccttgtctat tccattgata aatgaagcat cattttcttt tgttgtttga
     3121 gcaccactgt gaacacgaac aatagcacct gaaatatttt gtgagagggc atcgtagttg
     3181 atttcctcag gacgctgcca gccagagagg tcaataatcg gtttgtctaa gtgtttcaaa
     3241 gcctgtgctt caatctgtgc tatattggat tttgttttaa acgattggct gtcattaagt
     3301 gggcgattga tgattaaaat gaacatcata atcccaaaaa aactaaataa aataagtgga
     3361 tgaatttgtt ttctcatatc ttataagtct accctaaaaa tcaaaaaaaa tcaaaaaaat
     3421 gggttaagga agagacttta gagcattttt tcattcaaga gtgcggaatg atttgaaata
     3481 tggtataata aaagggaatt tctacagaaa agagaagatt atgtcaaatt ttgccattat
     3541 tttagcagcg ggtaaaggga ctcgcatgaa atctgatttg ccaaaagttt tgcacaaggt
     3601 tgcgggtatt tctatgttgg aacatgtttt ccgtagtgtg ggagctatcc aacctgaaaa
     3661 gacagtaaca gttgtaggac acaaggcaga attggttgag gaggtcttgg ctggacagac
     3721 agaatttgtg actcaatctg aacagttggg aactggtcat gcagttatga tgacagaacc
     3781 tatcttagaa ggtttgtcag gacacacctt ggtcattgca ggagatactc ctttaatcac
     3841 tggtgaaagc ttgaaaaact tgattgattt ccatatcaat cataaaaatg tggccactat
     3901 cttgactgct gaaacggata atccttttgg ctatggacga attgttcgta atgacaatgc
     3961 tgaggttctt cgtattgttg agcagaagga tgctacagat tttgaaaagc aaatcaagga
     4021 aatcaacact ggaacatacg tctttgacaa cgagcgtttg tttgaggctt tgaaaaatat
     4081 caataccaat aacgctcaag gcgaatacta tattacagac gtcattggta ttttccgtga
     4141 aactggtgaa aaagttggcg cttatacttt gaaagatttt gatgaaagtc ttggggtaaa
     4201 tgaccgtgtg gcgcttgcga cagctgagtc agttatgcgt cgtcgcatca atcataaaca
     4261 catggtcaac ggtgttagct ttgtcaatcc agaagcaact tatatcgata ttgatgttga
     4321 gattgctccg gaagttcaaa tcgaagccaa tgttaccttg aaagggcaaa cgaaaattgg
     4381 tgctgagact gttttgacaa atggtactta tgtagtggac agcactatcg gagcaggagc
     4441 ggtcattacc aattctatga ttgaggaaag tagtgttgca gacggtgtga cagtcggtcc
     4501 ttatgctcac attcgtccaa attcaagtct gggtgcccaa gttcatattg gtaactttgt
     4561 tgaggtgaaa ggatcttcaa tcggtgagaa taccaaggct ggtcatttga cttatatcgg
     4621 aaactgtgaa gtgggaagca acgttaattt cggtgctgga actattacag tcaactatga
     4681 cggcaaaaac aaatacaaga cagtcattgg agataatgtc tttgttggtt caaattcaac
     4741 cattattgca ccagtagaac ttggtgacaa ttccctcgtt ggtgctggtt caactattac
     4801 taaagacgtg ccagcagatg ctattgctat tggtcgcagt cgtcagatca ataaagacga
     4861 atatgcaaca cgtcttcctc atcatcctaa gaaccagtag gagcctatca tggagtttga
     4921 agaaaaaacg cttagccgaa aagaaatcta tcaaggacca atatttaaac tggtccaaga
     4981 tcaggttgaa ttaccagaag gcaagggaac tgcccaacgg gatttgattt tccacaatgg
     5041 ggctgtctgt gttttagcag taacggatga acaaaaactt atcttggtca agcagtaccg
     5101 caaagctata gaggctgtct cttacgaaat tccagccgga aaattggaag taggagaaaa
     5161 cacagcccct gtggcagctg cccttcgtga attagaggaa gaaacagcct atacagggaa
     5221 attagaactc ttgtacgatt tttattcagc tattggcttt tgtaatgaga agttaaaact
     5281 atatttagca agcgatttga caaaagtgga aaatccgcgt ccgcaggatg aggatgaaac
     5341 cttggaagtc cttgaagtga gcttagaaga agcgaaagaa ttaatccaat caggtcatat
     5401 ttgtgatgcc aaaacaatta tggctgttca gtattgggag ttgcagaaaa aatagaggag
     5461 gtcagtatgg gtaaatcttt attaacggat gaaatgattg aaagagctaa tagaggcgaa
     5521 aaaatttcag gtcctccttt gctagatgat aatgaggaaa ctaagatttt accaacctct
     5581 tcttcccgtt ttggttatgc caatcctaag gatcatggtt ttagccagga aaccttgaag
     5641 attcaggtcg aaccatctat tcataaaagc cgtcgtattg aaaataccaa gagaaatgtc
     5701 ttcaattcta agttgaataa aatcttattc gcggtcatct ttctcttgat tttgcttgtt
     5761 ttagcaatga aacttttgta atagaaaagg aattgaaatg aaaataggaa ttattgctgc
     5821 tatgccagaa gaactggctt atctggtcca gcatttagac aatgcccagg agcaagttgt
     5881 tttggggaat acctatcata caggaaccat tgcttctcat gaagtcgttc ttgtagaaag
     5941 tggaattggt aaggtcatgt ctgctatgag tgtggcgatt ttggctgatc atttccaggt
     6001 ggatgccctt attaatacgg gttcagctgg ggcagtagca gaaggtatcg ctgttgggga
     6061 tgtcgtgatt gctgacaaat tagcctatca tgacgtggat gtcacagctt ttggctatgc
     6121 ttatggacaa atggcgcaac aaccgcttta tttcgaatca gacaaaacct ttgttgctca
     6181 aatccaagag agtttatctc aattggacca aaactggcat cttggtttga ttgctacagg
     6241 agatagtttt gttgcaggaa atgacaagat agaagcgatt aagtcccatt tcccagaagt
     6301 tttagccgtg gagatggagg gggcagctat tgctcaagca gcgcatgccc tcaatctccc
     6361 agtcttagtc atcagagcta tgagtgacaa tgccaaccat gaagcaaaca tcttttttga
     6421 tgagtttatt atcgaagctg gacgtcgctc tgcccaagtc ttgttgacct ttttgaaggc
     6481 tttagattaa gcggaaattt gacagttttt ctagcttatg ataagattta agtaaagaaa
     6541 agctagaaaa cgtttcagag gatattatga gtattgaaat gaccgtcagt gagattgcag
     6601 aggtcttagg attatctcgc caagcaatca ataaccgtgt caaagaatta ccagaagaag
     6661 acacagataa aaatgacaaa ggggtaacag ttgttaccag aagtggcttg attaagctag
     6721 aagaaatcta taaaaaaacg atttttgaag atgagcctgt cagtgaagat gtcaaacaac
     6781 gtgaactgat ggagattcta gtggatgaga agaatgcaga aattcttcgt ctttatgaac
     6841 aattaaaagc caaggatcgt cagttatcag aaaaagacga gcagatgcgt atcaaagacc
     6901 gtcagattgc tgagaaagac aaacaattag atcagcaaca acaattgacc cttcaagcca
     6961 tgaaggatca agaaaatctt aagctagagc tggaccaagc aaaagaagaa gtccaatcca
     7021 ctaagaaagg cttttttgct cgtttatttg gaggataatc aaggagctgt ttaggttaaa
     7081 tgctaacctg atggcttctt ttgtttgtga atagtatagt tgattagaac agagacagta
     7141 gaggagaggt acagaatgga acgattagaa gattacattg cttttgactt agaatttaat
     7201 cagcacgaag gacaaacaca cttgattcaa gtatcggcag tgcgttttag agatggtcgg
     7261 gaaatcgatg cctatgattc ctatgttcat accagcgtcc ctctaaaaag ctttatcaat
     7321 ggtttgaccg ggattacagc tgagacctta aaagatgctc ctccagttga gaaagtctta
     7381 gaagaattcc aagagtttgt gggttctttg ctgatgatag gctacaatgc tgctaaaagt
     7441 gatttaccta ttttagcaga gcatggttta gactatagcc aacagtacaa ggtggatttg
     7501 tatgatgaag cttttgaacg tcggagttca gatttacatg gtattgccaa tctcaaattg
     7561 caaactgttg cctcatttct tggatttcaa ggtcagtctc ataatagttt agaggatgct
     7621 cggatgacgg cgcgtgttta cgaatccttc ttagagtcgg atcaagctag ggaattgtta
     7681 gagacagaaa gtagcttatc aaacaatcct tttggtggct tggacttgtc tcaattattt
     7741 gactaggagt gcctatgaaa cctgaaaaac ctaaaaaatt gggtcttaaa cagatttacc
     7801 tcaatcttga taaaatcctc tttctatttt tcttgatttt tatgatagtg gagtatttgt
     7861 gggtaccatt caattcatgg ttggctagct tcttattaga tcagacaggt tatcttttta
     7921 tttcctataa caatgtctta gccatcctta ctcattctcc attgattagt ctagcttttt
     7981 tagccttgat tgtaattaac cttctggttg cttattttca aataggactc ctctttattg
     8041 gtgctcgtca tctcctctat aatgaaaagc gaaggctaat tgagtatatc cgcaaggttt
     8101 tccatgaaag ttttggattt atgaaaaagc taacttgcgc taaagccttg tttatctttt
     8161 tctatatagc tatgcttttt ccttttatac ggaaaatgct gaagatttat tatcttaata
     8221 aaatcgtcat cccagagttt atccaagctt atttagaaga taaatattgg atgtggtggc
     8281 tgagcatcct acttctatct cttatctttc tctatgtctc tgtcagattg atgtttgccc
     8341 ttccgaagat tgtatatgat cagctgactg ttcgagaagc agtgatgttt agcttggaga
     8401 aaaccaagaa gagagttact ttttatgctt ggaatttatt ttacatcttg ctcaaagcac
     8461 atttattatt ttatcttcct ttgattcctt tattattggc tcaaactttg gtagatgata
     8521 tcactcagag agagtctctg attcttggta ttttgaattt tgtcgtgatt aaaaatctct
     8581 attatatggc tctgacttat tttttggtta aatttgtttc atttttgaca ggaaaggagt
     8641 tggatatgct tcctaggaga gaaaaagatc acatcgtgcg atggggtgtc atgacttgtg
     8701 ccagtctttt ctttgcctta gaaggttata tttatctgga ggctcccatg gttcatctac
     8761 ctcaacttat ttctcaccga ggggtttcca atgcaaatgg gattcaaaat acagtagagt
     8821 ccttggaaac tacagcacaa ctcaaaccag acttggtgga gacggacgtg caggaaacaa
     8881 aagatgggca gtttgtcatg atgcatgatg ctaacttgaa aaatttagca ggtatcaata
     8941 aaagtcctca agacttaaac ttggaggagc ttaaagggat tgatattttt gaaaatggct
     9001 accagactaa aatttcaagc tttgaagatt atctcagtcg agccaacgaa cttggtcaaa
     9061 aattactaat tgaaattaaa accagtaaaa aagatagtcc agacatgatg aaccgctttt
     9121 tagcccgtta tgctgcaaag ctcaagattt atggacatca aatccagtct ttagactacc
     9181 atgttgtcga aaaagtaaga cagtatgatg ccgaactgcc agtttatttc atcatgccct
     9241 acaattctgt ctttcctaaa acaagagcga caggatatac tatggagtac tcaaccttgg
     9301 atgaatattt tgtaagcaaa ctatggacaa cggatcagaa actttatgtc tggactgtca
     9361 atgattcaga agctatcagc aaatctcttc acttaggagt agatggagtg attacagatg
     9421 atttggaaaa agttcagcgg gaaatagaag tagcccaaga agatccagaa tatacggatt
     9481 tgctcttgaa aaaagcattg gaattctttg aattttagta ataaaaaaga ggaacggttg
     9541 ttcctcccat gataggtaag tattcttgtg aatgcttgct tttttgtggt tgcaatccgt
     9601 ttacgagaat tgtttgtatt gttcttgttt caatttactt tatagtgctt t
//
LOCUS       DAVHSI010000062         9564 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.063, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000062 DAVHSI010000000
VERSION     DAVHSI010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9564
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.063"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..566)
                     /locus_tag="VVR21_001960"
     CDS             complement(<1..566)
                     /locus_tag="VVR21_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU6055753.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTDERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSE"
     gene            complement(748..1710)
                     /gene="nrdF"
                     /locus_tag="VVR21_001961"
     CDS             complement(748..1710)
                     /gene="nrdF"
                     /locus_tag="VVR21_001961"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU6055754.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(1898..4057)
                     /gene="nrdE"
                     /locus_tag="VVR21_001962"
     CDS             complement(1898..4057)
                     /gene="nrdE"
                     /locus_tag="VVR21_001962"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU6055755.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4138..4356)
                     /gene="nrdH"
                     /locus_tag="VVR21_001963"
     CDS             complement(4138..4356)
                     /gene="nrdH"
                     /locus_tag="VVR21_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU6055756.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            4707..4970
                     /locus_tag="VVR21_001964"
     CDS             4707..4970
                     /locus_tag="VVR21_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU6055757.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            4976..6709
                     /gene="ptsP"
                     /locus_tag="VVR21_001965"
     CDS             4976..6709
                     /gene="ptsP"
                     /locus_tag="VVR21_001965"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU6055758.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            6964..9417
                     /gene="phtA"
                     /locus_tag="VVR21_001966"
     CDS             6964..9417
                     /gene="phtA"
                     /locus_tag="VVR21_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEU6055759.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRLQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNEDVDSLLKQLYALPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYH
                     FIPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQQTPEPSPGPQPAPNLKIDS
                     NSSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKK
                     ENVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDD
                     LLAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAY
                     VTPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRV
                     KGEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDL
                     FATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEV
                     PQVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEK
                     LLALLKGSNPSSVSKEKIN"
BASE COUNT         3025 a         1781 c         1980 g         2778 t
ORIGIN      
        1 tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac gaaagcttta
       61 gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc acctgtaata
      121 tcgcgataat ttccacctat taaaatcaaa tctgttaatt ttcgttcgct taaaatcaga
      181 aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc acgcgcaaaa
      241 aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac tagactgcct
      301 gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc aatatttgat
      361 cgctcatcag tcaaaaggga gttggttcga agtttttcag ctccaccatg cacacgaatc
      421 agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc tgaaacggct
      481 atttcgtcca taatctgttt aaccgttatg gttcctttgc tatttactat ctctaaaatt
      541 ttggttaatt tttcttgttt gagcatatta tcacctcgtt tcctactact atcttaccat
      601 aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa aaatatcgaa
      661 gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt tctagtttac
      721 tttttgatga ttgagagtgg tggagaatta gtctaaaccg tagttatagt catcgtcttg
      781 catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga agtcgtggtt
      841 ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag ctgaatctgg
      901 gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc gaaggaaggt
      961 tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc cttcttcatt
     1021 ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt gctcttcttc
     1081 aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt gaacagactc
     1141 gtcacgaata atcaatttaa tgatttctgc aacgttggca agtttgttgt taccgagata
     1201 gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga cgctggcaac
     1261 tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag ccttcttttg
     1321 taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct tagtattcaa
     1381 ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt ggatgttatt
     1441 gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa ccccagtttc
     1501 agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca agtctttctc
     1561 tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac gtgtatcgag
     1621 ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt cgatggcatt
     1681 ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt tagtattgcg
     1741 aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa aaagtcggaa
     1801 gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg attttatcag
     1861 tgctgcttag ggaaaaatag tgtttctatg ctagaaacta aatcacacag ctttcacatt
     1921 ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag atagacttga
     1981 ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt tgtttatttt
     2041 ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg gtgagtgaaa
     2101 gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta cgcatatcca
     2161 tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca gcagggtagt
     2221 agattttacc aattttcttt tcctgacgtt cttcaatacg ttgcgtaatc gggtggatag
     2281 aagcagaaac atcgttgatg tagctgatag aaccatttgg cgctacagca aggcgatttt
     2341 ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca gcaacaccag
     2401 ggataaaaac atttttgaag agttctttaa cacggtctga tgttggaaca aattcaccag
     2461 ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag ttgtggaagg
     2521 taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag ttcataagca
     2581 taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg agttgttggg
     2641 caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg ctatttccat
     2701 ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta agggcacgaa
     2761 ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc acgttggttg
     2821 aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca tcgttgatca
     2881 agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata atctttccat
     2941 cgacaggatt tgcacggtta gccgtatcga tgttgactac ataaggatag ccagactctt
     3001 gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc ttgcgaatat
     3061 ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg aatggcacac
     3121 cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt ttacgagcca
     3181 attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca cgtacttttt
     3241 catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga aagacgttga
     3301 ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag aagctgtctt
     3361 caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct ttgataggtg
     3421 caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata cgtgaaagtt
     3481 gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact tggattagga
     3541 aacaagatac caactcccca cgacgagcac gtccagcatt caagaaggaa ggagtagcag
     3601 gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct tcattcccat
     3661 cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga tagtattcac
     3721 cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg aatgacttga
     3781 attggaagtt ttggtctttg ataaattgag ccaattcttc caagaactct ggacggtatt
     3841 tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt ttgtctttga
     3901 ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca tccaaggctt
     3961 ccttatcttt atgaagcatg atttgtccat taacaggacg gttaatttcg ttattaagac
     4021 ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta tctaattaca
     4081 aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt actaagatta
     4141 tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg gtgtttggat
     4201 aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag gttgctcatc
     4261 aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg tcattttaca
     4321 ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct tcaaaattta
     4381 atactatctt agtatatcag aaaataaaat tttgtcaatg atttaaacta aatatagtgg
     4441 tgttcttttg ttgtttttat atataaacac aatatatagt gtttgtattg tgaaatagca
     4501 atgattatcc tataaattgt ttttgaagaa actatatcct gtgttttgtt atctaggata
     4561 gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa atgcttgaaa
     4621 aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata actcaaaaaa
     4681 agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta gtggcagaaa
     4741 caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa tttgcttcag
     4801 atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg ggtgttatga
     4861 gtcttggtgt tggtcaaggt gctgacgtaa ctatctcagc tgaaggtgca gatgcagatg
     4921 acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa gggaaatgac
     4981 agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag catatctact
     5041 cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg cagaagaagc
     5101 tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc gcgagaaagc
     5161 agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa tggttcttgc
     5221 tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag tgaatgcaga
     5281 agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca tggaagacaa
     5341 cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg tattggcaaa
     5401 ccttcttggt aaaaaattgc caaacccagc ttctatcaat gaagaagtga ttgtgattgc
     5461 gcatgacttg actccttcag atacagctca attggacaaa aactttgtaa aagcttttgt
     5521 aaccaacatc ggtggacgta caagccactc agctatcatg gcacgtacac ttgaaattgc
     5581 tgctgtatta ggtacaaaca acatcactga aatcgttaaa gacggtgaca tccttgctgt
     5641 taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg cagaatttaa
     5701 agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga aagatgctca
     5761 aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta ctccaaaaga
     5821 cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta cagagttctt
     5881 gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat acaaggctgt
     5941 tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg gtggagataa
     6001 ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat tccgtgctct
     6061 tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc gtgctcttct
     6121 tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc tcttgaaaga
     6181 attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg ctgaaggtgt
     6241 tgcagttgcg gataacattc aagttggtat catgatcgag attcctgcag cggctatgct
     6301 tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaatg acttgatcca
     6361 atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc aaccatacaa
     6421 cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg aaggtaaatg
     6481 ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc ttgtcggaat
     6541 gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca gcttgatgaa
     6601 gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag aatgctcaac
     6661 aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat cgaaaagtcc
     6721 ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca agaaaatctt
     6781 tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac ttaaatggtt
     6841 cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt aagtaataga
     6901 gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag aaagagagtt
     6961 tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat tttaagtgtt
     7021 tgttcttacg agttgggact gtatcaagct agaacggtta aggaaaataa tcgtgtttcc
     7081 tatatagatg gaaaacaagc gacgcaaaaa acggagaatt tgactcctga tgaggttagc
     7141 aagcgtgaag gaatcaatgc tgagcaaatc gtcatcaaga taacagacca aggctatgtc
     7201 acttcacatg gcgaccacta tcattattac aatggtaagg ttccttatga tgcgattttc
     7261 agtgaagaat tactcatgaa agatccaaac tataagctaa aagatgagga tattgttaat
     7321 gaggtcaagg gtggatatgt tatcaaggta gatggaaaat actatgttta ccttaaggat
     7381 gctgcccacg cggataacgt ccgtacaaaa gaggaaatca atcgacaaaa acaagagcat
     7441 agtcaacatc gtgaaggtgg gactccaaga aacgatggtg ctgttgcctt ggcacgttcg
     7501 caaggacgct atactacaga tgatggttat atctttaatg cttctgatat catagaggat
     7561 actggtgatg cttatatcgt tcctcatgga gatcattacc attacattcc taagaatgag
     7621 ttatcagcta gcgagttggc tgctgcagaa gccttcctat ctggtcgggg aaatctgtca
     7681 aattcaagaa cctatcgcct acaaaatagc gataacactc caagaacaaa ctgggtacct
     7741 tctgtaagca atccaggaac tacaaatact aacacaagca acaacagcaa cactaacagt
     7801 caagcaagtc aaagtaatga ggatgttgat agccttctga aacaacttta tgccttgcca
     7861 ctcagccaac gacacgtaga atctgatggc cttgtctttg atccagcaca aatcacaagt
     7921 cgaacagcta gaggtgttgc agtgccacac ggagatcatt accacttcat cccttactct
     7981 caaatgtctg aattggaaga acgaatcgct cgtattattc cccttcgtta tcgttcaaac
     8041 cattgggtac cggattcaag gccggaacaa ccaagtccac aacagactcc ggaacctagt
     8101 ccaggcccgc aacctgcacc aaatcttaaa atagactcaa attcttcttt ggttagtcag
     8161 ctggtacgaa aagttgggga aggatatgta ttcgaagaaa agggcatctc tcgttatgtt
     8221 tttgcgaaag atttaccatc tgaaactgtt aaaaatcttg aaagcaagtt atcaaaacaa
     8281 gagagtgttt cacacacttt aactgctaaa aaagaaaatg ttgctcctcg tgaccaagaa
     8341 ttttatgata aagcatataa tctgttaact gaggctcata aagccttgtt tgaaaataag
     8401 ggtcgtaatt ctgatttcca agccttagac aaattattag aacgcttgaa tgatgaatcg
     8461 actaataaag aaaaattggt agatgattta ttggcattcc tagcaccaat tacccatcca
     8521 gagcgacttg gcaagccaaa ttctcaaatt gagtatactg aagacgaagt tcgtattgct
     8581 caattagctg ataagtatac aacgtcagat ggttacattt ttgatgaaca tgatataatc
     8641 agtgatgaag gagatgcata tgtaacgcct catatgggcc atagtcactg gattggaaaa
     8701 gacagccttt ctgataagga aaaagttgca gctcaagcct atactaaaga aaaaggtatc
     8761 ctacctccat ctccagacgc agatgttaaa gcaaatccaa ctggagatag tgcagcagct
     8821 atttacaatc gtgtgaaagg ggaaaaacga attccactcg ttcgacttcc atatatggtt
     8881 gagcatacag ttgaggttaa aaacggtaat ttgattattc ctcataagga tcattaccat
     8941 aatattaaat ttgcttggtt tgatgatcac acatacaaag ctccaaatgg ctataccttg
     9001 gaagatttgt ttgcgacgat taagtactac gtagaacacc ctgacgaacg tccacattct
     9061 aatgatggat ggggcaatgc cagtgagcat gtgttaggca agaaagacca cagtgaagat
     9121 ccaaataaga acttcaaagc ggatgaagag ccagtagagg aaacacctgc tgagccagaa
     9181 gtccctcaag tagagactga aaaagtagaa gcccaactca aagaagcaga agttttgctt
     9241 gcgaaagtaa cggattctag tctgaaagcc aatgcaacag aaactctagc tggtttacga
     9301 aataatttga ctcttcaaat tatggataac aatagtatca tggcagaagc agaaaaatta
     9361 cttgcgttgt taaaaggaag taatccttca tctgtaagta aggaaaaaat aaactaatga
     9421 aaaatgaaag tctcgataaa gaggctttca tttttattat gtatatatgt aaaattcttg
     9481 acaagcaata ttaaaaagag taaactatta actagttaat taaccggttt attactttat
     9541 agtgaatcaa atatacttaa gaaa
//
LOCUS       DAVHSI010000063         9115 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.064, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000063 DAVHSI010000000
VERSION     DAVHSI010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.064"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..188
                     /locus_tag="VVR21_001967"
     CDS             <1..188
                     /locus_tag="VVR21_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055760.1"
                     /translation="LTFLIELFTSYFNSLYFPLYSMKIKAQTRKLATGCSKHCFEVVD
                     KTDEVSSKYCFEVADGS"
     gene            complement(372..1220)
                     /gene="dprA"
                     /locus_tag="VVR21_001968"
     CDS             complement(372..1220)
                     /gene="dprA"
                     /locus_tag="VVR21_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU6055761.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGMAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1316..2005)
                     /locus_tag="VVR21_001969"
     CDS             complement(1316..2005)
                     /locus_tag="VVR21_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU6055762.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(2017..2895)
                     /locus_tag="VVR21_001970"
     CDS             complement(2017..2895)
                     /locus_tag="VVR21_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU6055763.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2885..3754)
                     /gene="licA"
                     /locus_tag="VVR21_001971"
     CDS             complement(2885..3754)
                     /gene="licA"
                     /locus_tag="VVR21_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU6055764.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAAIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGTDEK"
     gene            complement(3771..4793)
                     /locus_tag="VVR21_001972"
     CDS             complement(3771..4793)
                     /locus_tag="VVR21_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU6055765.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4798..5505)
                     /locus_tag="VVR21_001973"
     CDS             complement(4798..5505)
                     /locus_tag="VVR21_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU6055766.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5841..7328
                     /gene="tacF"
                     /locus_tag="VVR21_001974"
     CDS             5841..7328
                     /gene="tacF"
                     /locus_tag="VVR21_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU6055767.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7338..8141
                     /locus_tag="VVR21_001975"
     CDS             7338..8141
                     /locus_tag="VVR21_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6055768.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8143..8952
                     /locus_tag="VVR21_001976"
     CDS             8143..8952
                     /locus_tag="VVR21_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU6055769.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2860 a         1828 c         1536 g         2891 t
ORIGIN      
        1 atttgacttt cctgatagag ttgttcacat cttatttcaa ttcactatac tttcccttat
       61 actcaatgaa aatcaaagcg caaactagga agctagccac aggttgctca aagcactgct
      121 ttgaggttgt agataagact gacgaagtca gctcaaaata ctgttttgag gttgcagatg
      181 gaagctgacg tagtttgaag agattttcga agagtattat atgagaaaaa tcctctactc
      241 tactaatcca cttagaaaaa acgcatatta tcaagtgtta aaaacttgct aatatgcgtt
      301 ttattatgga aatgttgggt tcattttctc ttaaaattga ttttttctta gaattctagc
      361 ttaggtcatt tttaaaattc aaattccgca agaacatctt gcccactggt gaccaatttt
      421 gctccttctt gaatcaaatg atggcaaccg tctgatagtc catctaaaat gctaccagga
      481 atagcaaaga catcgcgtcc ttcttccatt gctcgctcac acgtaatgag actacctgaa
      541 cgcatcttag cctctgctac aatcacacca cgacaaagtc cagcaatgat gcgattacgg
      601 gcaggaaaat gaaatttcag aggttgttcg ccaggtccat attcacttag aaccagatgg
      661 tcattgccga tgtagtcttg caagcgttta ttggctttag gataaaacac atccagtcct
      721 gttccaatca ctgcaatggt ttttccgcca ttctgaagag ctgccatatg agctgctgtg
      781 tcaatgccct tggccatacc actgacaata accagttcat tttccaagcc ttgaatgact
      841 ttttcaactg acttagctcc ctgtttgcta caagcacgac tgcccacgac cgctaccttc
      901 gggaatttca ggaggtcaag atttcccttg taaaataaaa gtacaggcgc atcatatatt
      961 tcactcaaat cccaaggata acagtcatct aaaatagaga aagatggaaa tttttgaaac
     1021 tctttcgaca aatgcgcatc gtctatctga aaataacgtt ccataaaaac ggctggatta
     1081 cggcaacctg agatatctgc aatatcaccc aataaaagct cctgatcaac attttcaccg
     1141 tattctagca ctttcaaaat ctgttgattg gtcaaacctg atttttttaa cttatagatt
     1201 tcatagtttg tgattttcat aaataactcc atttcttttt ctactcatct atctattcgt
     1261 aaaagttcgt aaaaaatcaa aaaacatccg actattttgt cagatgttgg aatctttaat
     1321 tttcgttttt aagaatttct tctaatttac gatagtcttg gacactatcg atctcataaa
     1381 tgctattgcc ttctaattct tcaacataga catctagctc tttgatatta tccttaacca
     1441 tattgtccca gtagagatca acaaattcgc cacttgcata agccttgtcg ataaagctga
     1501 caatcttttc tgcagttgga gcatcccaga aggatacacc actaaggatg cgacctgcct
     1561 tgctatcaac aataatgtct tgaaccttgt agtcatctcc atagaccaag aaccattcgt
     1621 tggtacaatc ttcacgataa acactaaaat aagtcgaacg tgtcaaatca ttgcggaaca
     1681 tatttttaaa gagataattg tcagcatcaa taacatagct gttggccaat tcttctttta
     1741 caagatagag agagtaaaag ttattgtagt cagcgtattt atcattgaaa acgaggcgaa
     1801 caccgtattt ttcttttaaa taatcgaatt gttctttaag ataaccaacg atgatgatga
     1861 tgtcattgat tcctttttct ttgagaaact caatttggta ttcaatcaaa ggtttttgat
     1921 taacctgaac caaggcttta ggggtatttt cagtcatagg acgcaagcga gttcccaatc
     1981 ccgctgctaa gataatggct ttcacacgaa tctcctttat tctttaataa taatataaac
     2041 tccagcaatg acgacaagtg acgtcataat ggtcagcata tctagcggtg cacccaagaa
     2101 aacaactgca aacaagaccg tccatactac atagctcacg ttcaagcctg tagccttggc
     2161 tggttgcaag cgattgatag cgatataata agccaagtag gaaatcatat caaaggctgc
     2221 aaaaacaatc atgagaccta gcaattgtcc attggctact gcagtaaatg actgatgaga
     2281 gaagagcaca atcacaagat aggacaagaa cgaagtcact tgacggatta agagggcttc
     2341 gatttcactc agttcacttt ccatagcaaa ggagctaaga acactctcac ttccccatgc
     2401 aatagcacaa accaaagcac agagaatccc aatgtagaag gaattaacct gttcaacctt
     2461 ataggtctgg gcaataatcc ctccaataat caagacaatc ccaaatacag tatttttcga
     2521 aattttgtgc ttcaaaaaga agaaagccaa tagaactgaa atcgcagggt aaatagccga
     2581 tacagatgaa gctaaagaac ttccgatata cttaactgca taaagattgg cctgcatacc
     2641 gatagggcct gctagcaagg ctccgatgat aacactgaca ttgcgaatat ttaagaaaat
     2701 tgagaggcga actttccctt cttttaccaa gagaaaagct agtaagataa agatgctcaa
     2761 aaaatcatga gctgcagcca ccacaaaggg tgacaaatct gtaaaaatcg aaaagatata
     2821 agcactaacc gttagaccca agccccagaa aatacctgag agaaggccaa aaggaactcc
     2881 gtttttactt ttcatctgtt cctccataag aagccaaacc tttaacagct ctttggtaac
     2941 gattcacacc atagtcacca aaatcttcac cttgctcttc cttatagaca gtccatagac
     3001 tccaaatagt atcttgtaaa attttataaa tagcaatctt ttcatgagaa accggtgttt
     3061 ggtcactctc atagtgagat aagaaagttt cttcctcttg ggaagtgaat tcagactcta
     3121 aaaagagggc agccaaatcc cacattggat cattcattga tgaatattcc cagtcaatca
     3181 aataaagtcg tccttgaggt gattcgataa agttttcagg caccaaatcg atatgacaag
     3241 attttctgtc aacacctaag tcagccagtc ttttctctaa ggagaagact gcatttctaa
     3301 cagattcata gttggcataa ggaatttgtt cttcaatcaa ggattcgtat tttttgattt
     3361 cttcaaaagg agcaaattct cctcttaatt ccttagcaga cgtatgaata gtttgtaata
     3421 ttggagcaat tttgtcgaac ttggtcttga ttgacgttga atcaagcgta atcgcagatt
     3481 cgatatactc atttactttg atagcagctt caatatcaaa aagataattt tttacatcta
     3541 agcctaaatc ctttagtagt tcaagattgt acttttcatc ttgtcgattg ataagctttt
     3601 ctgtcccttt accaaagaat ttaacaatgt attgcttatt tgttgttttg gccaaatagt
     3661 tttgattggt cattccaccc agttgttcaa cactgaggac ttcctcttct tgactaagta
     3721 aggaagaaat tttttcttta atgattttct ccacaattaa cctccagtac ttatacttcc
     3781 cacttaaaca ctgttttaaa ggctgtgttt aaatcggttg caaagacacg atgaatatct
     3841 ttaatttctc ttacaggttc ttctagataa aggatatttt taagacgatt ggcaaatttc
     3901 ttgacttcca tcatttggat agcattttta aaatcaatgc gaccagaacg agatgaccca
     3961 accaaaatca agcccttttc taaggcatcg cgagtattga gattgacttt atattcgcta
     4021 actcccatca tgagaatcgt tccctgagga cgaatgtagc gaatcaagtc attaatagct
     4081 ggtccagtac catcaccacc acaacattca aaagcatggt caaaggccaa ctcttcagga
     4141 atattatccg taatatagca ttctttggca aatgagaaga gttccaactt ttcccaatga
     4201 cgaccaataa ccacaatctc tgattctggc aaagtatagt tgataatatt ggcaaccaca
     4261 aaagctaaac ttccatctcc aataacggcg atccgctccc gcttgctatg agcaagagtc
     4321 aatagacgat tcatagcgtg catgcccaca ctgacaaact ctgtaatggc tgcaaccgta
     4381 tcttcaatag catcataagc caccacacga tctttaggga gagaaacaaa ctctctcata
     4441 aagccatcaa atccactaga caagaaatgg gtccctgtca tgtagttttc atagaattct
     4501 tcatcactct gcataggaga ctgattggga atcatgacaa ctttttgacc aacctcgtag
     4561 gttccggtcg ggtcagaaat gacggttcca catgactcgt gaatcattgc cattggaagc
     4621 tttttattca aaatcttggg atcacgtttt ccctgatagt aacgctgatc cgcatgacag
     4681 acagccatgt agttgggacg gataaggata tgattctctt ggtcaatagc ctcttcctga
     4741 tatttgacat tgataaactt aggcttagtt agttgataaa tttgattaat cattttacta
     4801 gtctttctca atcatacttt ttgcaatctt caaatctgtt acggttgtaa tcttcagatt
     4861 tgagtattca cctttggcca aggccacatc ttttcctttg atcacaaaga ttttacatgc
     4921 atctgtcaag atttccttct cttcatcaga aagagatcca taaaggtcca tgaagtcctt
     4981 gcaacggaat gtttgaggtg tttgtccttg ataaaggtga gcacgatttg gaatatctgt
     5041 aataaattga ccattggtac tttcaacgat agtatcaact gcttctacca ctgtgtccac
     5101 tgcgtcatga ttttgggcaa gttggatatt gtcctgaatc atgcgaagtg taataaatgg
     5161 acgaacagaa tcgtgggtaa caacgatatc ctctggagta agcggacgat aagcatcaat
     5221 ggcttcaatg attttcttaa tacttgtatt gcggtcagca ccaccctttg taatgatgat
     5281 acgttcctta taaagaggaa gatatttatc tacaagatct tctgcatgag aaacccagtc
     5341 tccatgaaca ccaactacaa ttttttcaat acttggctcc aagacaaatt tttcaattgt
     5401 atgaatcaaa ataggtcgat cacctagctc taaaaattgt tttggcaagt tactgatccc
     5461 catgcgtgtg ccagttccac cggcaagaat tcctgcataa atcatctatt ttctcctttg
     5521 tcttactaaa aaaacttatt ctctctatta taccacaatc tagtcctatc ataaaagaaa
     5581 tactggtcct ccccttctag aataggagaa ttatgcagtt ctattattca aagaaactag
     5641 tccatttcta gtaatgacta ggaattctgt agcaattact aataaatggc tgcgaaattt
     5701 tagagtcctt cagaataata tactttcctt aaagaaaact taaaacttaa gatttgaaac
     5761 ttcaaagtga ttacttgact tactgccctt catttcttat tagctaactt tatgatataa
     5821 tgaaaaacga ggtaaattga atgaaaagta taaaattaaa tgctctatct tacatgggaa
     5881 ttcgtgtctt gaatattatt tttcccatcc taactggaac ctatgtcgcg cgtgtcttgg
     5941 accgaactga ctatggttac ttcaactcag tcgacactat tttgtcattt ttcttgccct
     6001 ttgcaactta tggtgtctat aactacggtt taagggctat cagtaatgtc aaggataaca
     6061 aaaaagatct taacagaacc ttttctagtc ttttttattt gtgcatcgct tgtacgattt
     6121 tgaccactgc tgtctatatc ctagcctatc ctctcttctt tattgataat ccaatcgtca
     6181 aaaaggtcta ccttgttatg gggattcaac tcattgccca gattttttca atcgaatggg
     6241 tcaatgaagc tctggaaaat tacagttttc tcttttacaa aactgccttc atccgtatcc
     6301 tgatgctggt ctctattttc ttatttgtta aaaatgaaca cgatattgtt gtctatacac
     6361 ttgtgatgag tttatcgacg ctgattaact acctgattag ttatttttgg attaaaagag
     6421 acatcaaact tgttaagatt cacctaagtg attttaaacc actctttctc cctctgacag
     6481 ccatgttagt ctttgccaat gccaatatgc tcttcacttt tttagatcgc ctcttcctcg
     6541 ttaaaacagg gattgatgtc aacgttagtt actataccat agctcagcga attgtgaccg
     6601 ttatagctgg ggttgtaaca ggtgcaattg gagtgagtgt gcctcgtctc agttactatc
     6661 tggggaaagg agacaaagaa gcctatgttt ctctggttaa tagaggtagt cgaatcttta
     6721 acttctttat cattccactg agttttggac tcatggtttt aggaccaaat gccatcctac
     6781 tttacggtag tgaaaaatat atcggaggcg gcatcttgac ctctctcttc gcttttcgta
     6841 cgattatcct ggccttagat accattcttg gttcccaaat tctctttacc aatggctatg
     6901 aaaaacgtat cacagtctat acagtctttg ctgggctact caatttgggc ttgaatagtc
     6961 tcctcttttt caaccatatc gtggttcctg aatactactt actgacaact atgttatcag
     7021 agacttctct acttgttttc tatattattt tcatccatag aaaacaactc atccacttgg
     7081 gacatatctt tagctatact gttcgatact ctctcttttc actttccttt gtagcaattt
     7141 atttcctgat taatttcgtg tatcctgtgg atatggtcat taatttgcca tttttaatta
     7201 atactggttt gattgtcttg ctatcagcta tctcttatat tagtctactt gtcttcacaa
     7261 aagatagcat tttctatgaa tttttaaacc atgtcctagc cttaaaaaat aaattcaaaa
     7321 aatcatagga gtttaaaatg aaacaactaa ccattgaaga tgccaaacaa attgaattag
     7381 aaattttgga ttatattgat actctctgta aaaagcacaa tatcaactat attattaact
     7441 acggtactct gattggggcg gttcgacatg agggctttat cccttgggac gacgatattg
     7501 atttatccat gcctagagaa gactaccaac gatttattaa catttttcaa aaggaaaaaa
     7561 gcaagtataa gctcctatcc ttagaaactg ataagaacta ctttaacaac tttatcaaga
     7621 taaccgacag tacgactaaa attattgata ctcgaaatac aaaaacctat gagtctggta
     7681 tctttatcga tattttccct atagatcgct ttgatgatcc taaggtcatt gatacttgtt
     7741 ataaactgga aagcttcaaa ctgctgtctt tcagtaaaca taaaaatatt gtctataagg
     7801 atagcctttt aaaagattgg atacgaacag ccttctggtt actccttcga ccggtttctc
     7861 ctcgttattt tgcaaataaa atcgagaaag aaattcaaaa atatagtcgt gaaaatgggc
     7921 aatatatggc ttttatccct tcaaaattta aggaaaagga agtcttccca agtggtacct
     7981 ttgataaaac aatcgattta ccctttgaga atttaagcct tcctgcacct gaaaaatttg
     8041 atactatttt gacacaattt tatggagatt atatgaccct accaccagaa gaaaaacgct
     8101 tctacagtca tgaatttcac gcttataaat tggaggatta ggatgcaata tttagaaaaa
     8161 aaagaaatta aagaaattca actagccctg ctggactata ttgatgagac ttgtaagaaa
     8221 tatgatattc cttattttct cagttatgga accatgcttg gagccatccg ccacaaaggt
     8281 atgattcctt gggatgatga tattgatatt tccctttatc gtgaggatta tgagcgttta
     8341 ctgaagatta ttgaagaaga aaatcaccct cgctacaagg ttctttccta cgatacatct
     8401 tcttggtact tccataattt cgcatcgatt ttggacactt ctactgttat agaagaccat
     8461 gttaagtaca agcgtcatga taccagcctt ttcatcgatg tcttcccaat tgatcgattt
     8521 acagacttga gcattgtcga caagagctat aagtatgtgg ctcttcgtca actagcttat
     8581 atcaaaaaat cacgagcagt tcacggtgat agcaaactaa aagattttct tagattatgt
     8641 agctggtacg ctctccgatt tgtcaatcct cgctactttt acaagaaaat tgatcaacta
     8701 gtcaaaaatg ctgtaaccaa cactcctcaa tatgaaggag gagttgggat cggtaaggaa
     8761 gggatgaaag aaatcttccc agttgatacc tttaaagaac tgattttaac tgagtttgag
     8821 ggccgtatgt tgcctgttcc caaaaaatat gaccaatttt taacccagat gtatggcgat
     8881 tatatgacac caccatcaaa agaaatgcaa gagtggtata gtcatagcat taaagcttat
     8941 cgcaaaaact gattgagggg gattatacaa actactaaga tagaggttat tcaaaaacat
     9001 aattttagta gaaaatgaaa tacatattcc cacaataaaa cgcatcatat caaggttttt
     9061 gaaaaatctt gatatgatgc gttttataat tttaaagact tttttctata gtaga
//
LOCUS       DAVHSI010000064         8400 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.065, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000064 DAVHSI010000000
VERSION     DAVHSI010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.065"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..2505
                     /gene="mfd"
                     /locus_tag="VVR21_001977"
     CDS             <1..2505
                     /gene="mfd"
                     /locus_tag="VVR21_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU6055770.1"
                     /translation="YFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEF
                     FNQFSFLKEEIERYKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESV
                     NLIEGNLRHGFHFVDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYV
                     VHHIHGIGQYLGIETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPK
                     LNKLNDGHFKKAKQKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPY
                     VETDDQLRSIEEIKRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVP
                     TTVLAQQHYTNFKERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLS
                     KDVVFADLGLMIIDEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDL
                     SVIETPPTNRYPVQTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQE
                     LIPEASIGYVHGRMSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENAD
                     HMGLSTLYQLRGRVGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAM
                     RDLSIRGAGNLLGKSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQ
                     IDAYLPDTYISDQRHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGL
                     VKSYLDKVFVQRVERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLME
                     LVFDVQNKKDYEILEGLLIFGESLLEIKESKEENSI"
     gene            2563..2829
                     /locus_tag="VVR21_001978"
     CDS             2563..2829
                     /locus_tag="VVR21_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU6055771.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            2822..3190
                     /locus_tag="VVR21_001979"
     CDS             2822..3190
                     /locus_tag="VVR21_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU6055772.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            3310..4578
                     /locus_tag="VVR21_001980"
     CDS             3310..4578
                     /locus_tag="VVR21_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU6055773.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            4575..5852
                     /gene="tilS"
                     /locus_tag="VVR21_001981"
     CDS             4575..5852
                     /gene="tilS"
                     /locus_tag="VVR21_001981"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU6055774.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            5856..6398
                     /gene="hpt"
                     /locus_tag="VVR21_001982"
     CDS             5856..6398
                     /gene="hpt"
                     /locus_tag="VVR21_001982"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU6055775.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            6414..8372
                     /gene="ftsH"
                     /locus_tag="VVR21_001983"
     CDS             6414..8372
                     /gene="ftsH"
                     /locus_tag="VVR21_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU6055776.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT         2893 a         1247 c         1727 g         2533 t
ORIGIN      
        1 tatttttctg atattgaaca aatctataaa aaacaaagtc cagtgacctt tttctctaat
       61 cttcaaaagg gtttaggaaa tctcaaattt gacaaaattt atcaattcaa tcaatatcct
      121 atgcaggaat ttttcaatca gttttctttt ctaaaagaag aaattgaacg atataaaaaa
      181 atggattaca ccattattct gcagtctagc aattcaatgg gaagtaaaac attggaggat
      241 atgttagagg aatatcagat taaattggat tctagagata agacaaacat ctgtaaagaa
      301 tctgtaaact taatagaggg taatctcaga catggttttc attttgtaga tgaaaagatt
      361 ttattgataa ctgaacatga gatttttcaa aagaaattaa agcgtcgttt tcgaagacaa
      421 catgtttcaa atgcagagag attaaaagat tacaatgaac ttgaaaaagg ggactatgtt
      481 gtccatcata tccatgggat tggtcaatat ctaggaattg aaaccattga aatcaaggga
      541 attcatcgcg attatgtcag tgtccaatac caaaatggtg atcaaatttc tatccccgtg
      601 gaacagattc atctactgtc caaatatatt tcaagtgatg gtaaagctcc aaaactcaat
      661 aaattaaatg acggtcattt taaaaaggcc aagcaaaagg ttaagaacca ggtagaggat
      721 atagctgatg atttaatcaa actctactct gaacgtagtc agttgaaggg ttttgctttc
      781 tcagctgatg atgatgatca agatgccttt gatgatgctt tcccttatgt tgaaacggat
      841 gatcaacttc gtagtattga ggaaatcaag agggatatgc aggcttctca gccaatggat
      901 cgacttttag ttggggatgt tggttttgga aagactgaag ttgctatgcg tgcagccttt
      961 aaagcagtca atgatcacaa acaggttgtc attctagttc cgacgacggt tttagcgcaa
     1021 cagcactata cgaattttaa ggaacgattc caaaattttg cagttaatat tgatgtgttg
     1081 agtcgcttta gaagtaaaaa agagcagact gcaacacttg aaaaattgaa aaacggtcaa
     1141 gtcgatattt tgattggaac acatcgtgtt ttgtcaaaag atgttgtgtt tgctgatttg
     1201 ggcttgatga ttattgatga ggaacagcga tttggtgtca agcataagga aactttgaaa
     1261 gaactgaaga aacaagtgga tgtcctaacc ttgaccgcta cgccaatccc tcgtaccctc
     1321 catatgtcta tgctgggaat cagagattta tctgttattg aaactccgcc gactaatcgc
     1381 tatcctgttc agacctatgt tttggaaaag aatgatagtg tcattcgtga tgctgtcttg
     1441 cgtgaaatgg agcgtggagg tcaagtttat tatctttaca acaaagttga cacaattgtt
     1501 cagaaggttt cagaattaca ggagttgatt ccggaggctt cgattggata tgttcatggt
     1561 cgaatgagtg aagtccagtt ggaaaatact ctattagact ttattgaggg acaatacgat
     1621 atcttggtga cgactactat tattgagaca ggggtggaca ttccaaatgc taatacttta
     1681 tttattgaaa atgcggacca tatgggcttg tcaaccttat atcagttaag aggaagagtc
     1741 ggtcgtagta atcgtattgc ttatgcttat ctcatgtatc gtccagaaaa atcaatcagt
     1801 gaagtctctg aaaagagatt agaagcgatt aaaggattta cagaattggg ctctggcttt
     1861 aagattgcaa tgcgagatct ttcgattcgt ggagcaggaa atcttttagg aaaatcccag
     1921 tctggtttca ttgattctgt tggttttgaa ttgtattcgc agttattaga ggaagctatt
     1981 gctaaacgaa acggtaatgc taacgctaac acaagaacca aagggaatgc tgagttgatt
     2041 ttgcaaattg atgcctatct tcctgatact tatatttctg atcaacgaca taagattgaa
     2101 atttacaaga aaattcgtca aattgacaac cgtgtcaatt atgaagagtt acaagaggag
     2161 ttgatagacc gttttggaga atacccagat gtagtagcct atctgttaga gattggtttg
     2221 gtcaaatcat acttggacaa ggtctttgtt caacgtgtgg aaagaaaaga taataaaatt
     2281 acaattcaat ttgaaaaagt cactcaacga ctgtttttag ctcaagatta ttttaaagct
     2341 ttatccgtaa cgaacttaaa agcaggcatc gctgagaata agggattaat ggagcttgta
     2401 tttgatgtcc aaaataagaa agattatgaa attttagaag gtttgctgat ttttggagaa
     2461 agtttattag agataaaaga gtctaaggaa gaaaattcca tttgatattt ttcttctata
     2521 aaatagataa aaatggtaca ataataaatt gaggtaataa ggatgagatt agataaatat
     2581 ttaaaagtat cgcgaattat caagcgtcgt acagtcgcaa aggaagtagc agataaaggt
     2641 agaatcaagg ttaatggaat cttggccaaa agttcaacgg acttgaaagt taatgaccaa
     2701 gttgaaattc gctttggcaa taagttgctg cttgtaaaag tactagagat gaaagatagt
     2761 acaaaaaaag aagatgcagc aggaatgtat gaaattatca gtgaaacacg ggtagaagaa
     2821 aatgtctaaa aatattgtac aattgaataa ttcttttatt caaaatgaat accaacgtcg
     2881 tcgctacctg atgaaagaac gacaaaaacg gaatcgtttt atgggagggg tattgatttt
     2941 gattatgcta ttatttatct tgccaacttt taatttagcg cagagttatc agcaattact
     3001 ccaaagacgt cagcaattag cagacttgca aactcagtat caaactttga gtgatgaaaa
     3061 ggataaggag acagcatttg ctaccaagtt gaaagatgaa gattatgctg ctaaatatac
     3121 acgagcgaag tactattatt ctaagtcgag ggaaaaagtt tatacgattc ctgacttgct
     3181 tcaaaggtga taaaatggaa aatttattag acgtaataga gcaatttttg agtttgtcag
     3241 atgaaaagct ggaagaattg gctgataaaa atcaattatt gcgtttacaa gaagaaaagg
     3301 aaaggaagaa tgcgtaaatt cttaattatt ttgttgctac caagtttttt gaccatttca
     3361 aaagtcgtta gcacagaaaa agaagtcgtc tatacttcga aagaaattta ttacctttca
     3421 caatctgact ttggtattta ttttagagaa aaattaagtt ctcccatggt ttatggagag
     3481 gttcctgttt atgcgaatga agatttagta gtggaatctg ggaaattgac tcccaaaaca
     3541 agttttcaaa taaccgagtg gcgcttaaat aaacaaggaa ttccagtatt taagctatca
     3601 aatcatcaat ttatagctgc ggacaaacga tttttatatg atcaatcaga ggtaactcca
     3661 acaataaaaa aagtatggtt agaatctgac tttaaactgt acaatagtcc ttatgattta
     3721 aaagaagtga aatcatcctt atcagcttat tcgcaagtat caatcgacaa gaccatgttt
     3781 gtagaaggaa gagaatttct acatattgat caggctggat gggtagctaa agaatcaact
     3841 tctgaagaag ataatcggat gagtaaagtt caagaaatgt tatctgaaaa atatcagaaa
     3901 gattctttct ctatttatgt taagcaactg actactggaa aagaagctgg tatcaatcaa
     3961 gatgaaaaga tgtatgcagc cagcgttttg aaactctctt atctctatta tacgcaagaa
     4021 aaaataaatg agggtcttta tcagttagat acgactgtaa aatacgtatc tgcagtcaat
     4081 gattttccag gttcttataa accagaggga agtggtagtc ttcctaaaaa agaagataat
     4141 aaagaatatt ctttaaagga tttaattacg aaagtatcaa aagaatctga taatgtagct
     4201 cataatctat tgggatatta catttcaaac caatctgatg ccacattcaa atccaagatg
     4261 tctgccatta tgggagatga ttgggatcca aaagaaaaat tgatttcttc taagatggcc
     4321 gggaagttta tggaagctat ttataatcaa aatggatttg tgctagagtc tttgactaaa
     4381 acagattttg atagtcagcg aattgccaaa ggtgtttctg ttaaagtagc tcataaaatt
     4441 ggagatgcgg atgaatttaa gcatgatacg ggtgttgtct atgcagattc tccatttatt
     4501 ctttctattt tcactaagaa ttctgattat gatacgattt ctaagatagc caaggatgtt
     4561 tatgaggttc taaaatgagg gaaccagatt ttttaaatca ttttctcaag aagggatatt
     4621 tcaaaaagca tgctaaggcg gttctagctc tttctggtgg attagattct atgtttctat
     4681 ttaaggtatt gtctacttat caaaaagagt tagagattga attgattcta gctcatgtga
     4741 atcataagca gagaattgaa tcagattggg aagaaaagga attaaggaag ttggctgctg
     4801 aagcagagct tcctatttat atcagcaatt tttcaggaga attttcagaa gcgcgtgcac
     4861 gaaattttcg ttatgatttt tttcaagagg tcatgaaaaa gacaggtgcg acagctttag
     4921 tcactgccca ccatgctgat gatcaggtgg aaacgatttt tatgcgcttg attcgaggaa
     4981 ctcgcttgcg ctatctatca ggaattaagg agaagcaagt agtcggagag atagaaatca
     5041 ttcgtccctt cttgcatttt cagaaaaaag actttccatc aatttttcac tttgaagata
     5101 catcaaatca ggagaatcat tattttcgaa atcgtattcg aaattcttac ttaccagaat
     5161 tggaaaaaga aaatcctcga tttagggatg caatcttagg cattggcaat gaaattttag
     5221 attatgattt ggcaatagct gaattatcta acaatattaa tgtggaagat ttacagcagt
     5281 tattttctta ctctgagtct acacaaagag ttttacttca aacttatctg aatcgttttc
     5341 cagatttgaa tcttacaaaa gctcagtttg ctgaagttca gcagatttta aaatctaaaa
     5401 gccagtatcg tcatccgatt aaaaatggct atgaattgat aaaagagtac caacagtttc
     5461 agatttgtaa aatcagtccg caggctgatg aagaggaaga tgaacttgtg ttacactatc
     5521 aaaatcaggt agcttatcaa ggatatttat tttcctttgg acttccatta gaaggtgaat
     5581 caattcaaca aatacctgtt tcacgtgaaa catccataca cattcgtcat cgaaaaacag
     5641 gagatgtttt gattcaaaat gggcatagaa aaaaactcag acgtttattt attgatttga
     5701 aaatccctat ggaaaagaga aactctgctc ttattattga gcaatttggt gaaattgtct
     5761 caattttggg aattgcgacc aataatttga gtaaaaaaac gaaaaatgat ataatgaaca
     5821 ctgtacttta tatagaaaaa atagataggt aaaaaatgtt agaaaacgat attaaaaaag
     5881 tcctcgtttc acacgatgaa attacagaag cagctaaaaa actaggtgct caattaacta
     5941 aagattatgc aggaaaaaat ccaatcttag ttgggatttt aaaaggatct attcctttta
     6001 tggctgaatt ggtcaaacat attgatacac atattgaaat ggacttcatg atggtttcta
     6061 gctaccatgg tggaacagca agtagtggtg ttatcaatat taaacaagat gtgactcaag
     6121 atatcaaagg aagacatgtt ctatttgtag aagatatcat tgatacaggt caaactttga
     6181 agaatttgcg agatatgttt aaagcaagag aagcagcttc tgttaaaatt gcaaccttgt
     6241 tggataaacc agaaggacgt gttgtagaaa ttgaggcaga ctatacctgc tttactatcc
     6301 caaatgagtt tgtagtaggt tatggtttag actacaaaga aaattatcgt aatcttcctt
     6361 atattggagt attgaaagag gaagtgtatt caaattagaa agaataatct ttaatgaaaa
     6421 aacaaaataa tggtttaatt aaaaatcctt ttctatggtt attatttatc tttttccttg
     6481 tgacaggatt ccagtatttc tattctggga ataactcagg aggaagtcag caaatcaact
     6541 atactgagtt ggtacaagaa attaccgatg gtaatgtaaa agaattaact taccaaccaa
     6601 atggtagtgt tatcgaagtt tctggtgtct ataaaaatcc taaaacaagt aaagaaggaa
     6661 caggtattca gtttttcacg ccatctgtta ctaaggtaga gaaatttacc agcactattc
     6721 ttcctgcaga tactaccgta tcagaattgc aaaaacttgc tactgaccat aaagcagaag
     6781 taactgttaa gcatgaaagt tcaagtggta tatggattaa tctactcgta tccattgtgc
     6841 catttggaat tctattcttc ttcctattct ctatgatggg aaatatggga ggaggcaatg
     6901 gccgtaatcc aatgagtttt ggacgtagta aggctaaagc agcaaataaa gaagatatta
     6961 aagtaagatt ttcagatgtt gctggagctg aggaagaaaa acaagaacta gttgaagttg
     7021 ttgagttctt aaaagatcca aaacgattca caaaacttgg agcccgtatt ccagcaggtg
     7081 ttcttttgga gggacctccg gggacaggta agactttgct tgctaaggca gtcgctggag
     7141 aagcaggtgt tccattcttt agtatctcag gttctgactt tgtagaaatg tttgtcggag
     7201 ttggagctag tcgtgttcgc tctctttttg aggatgccaa aaaagcagca ccagctatca
     7261 tctttatcga tgaaattgat gctgttggac gtcaacgtgg agttggtctc ggcggaggta
     7321 atgacgaacg tgaacaaacc ttgaaccaac ttttgattga gatggatggt tttgagggaa
     7381 atgaagggat tatcgtcatc gctgcgacaa accgttcaga tgtacttgat cctgcccttt
     7441 tgcgtccagg acgttttgat agaaaagtat tggttggccg tcctgatgtt aaaggtcgtg
     7501 aagcaatctt gaaagttcac gctaagaaca agcctttagc agaagatgtt gatttgaaat
     7561 tagtggctca acaaactcca ggctttgttg gtgctgattt agagaatgtc ttgaatgaag
     7621 cagctttagt tgctgctcgt cgcaataaat cgataattga tgcttcagat attgatgaag
     7681 cagaagatag agttattgct ggaccttcta agaaagataa gacagtttca caaaaagaac
     7741 gagaattggt tgcttaccat gaggcaggac ataccattgt tggtctagtc ttgtcgaatg
     7801 ctcgcgttgt ccataaggtt acaattgtac cacgcggccg tgcaggcgga tacatgattg
     7861 cacttcctaa agaggatcaa atgcttctat ctaaagaaga tatgaaagag caattagctg
     7921 gcttaatggg tggacgtgta gctgaagaaa ttatctttaa tgtccaaact acaggagctt
     7981 caaacgactt tgaacaagcg acacaaatgg cacgtgcaat ggttacagag tacggtatga
     8041 gtgaaaaact tggcccagta caatatgaag gaaaccatgc tatgtttggt gcacagaatc
     8101 ctcaaaaatc aatttcagaa caaacagctt atgaaattga tgaagaggtt cgttcattat
     8161 taaatgaggc acgaaataaa gctgctgaaa ttattcagtc aaatcgtgaa actcacaagt
     8221 taattgcaga agcattattg aaatacgaaa cattggatag tacacaaatt aaagctcttt
     8281 acgaaacagg aaagatgcct gaagcagtag aagaggaatc tcatgcacta tcctatgatg
     8341 aagtaaagtc aaaaatgaat gacgaaaaat aaccctgaga gaggctggag cctctctttt
//
LOCUS       DAVHSI010000065         8228 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.066, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000065 DAVHSI010000000
VERSION     DAVHSI010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8228
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.066"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            169..1488
                     /locus_tag="VVR21_001984"
     CDS             169..1488
                     /locus_tag="VVR21_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU6055777.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            1494..3365
                     /locus_tag="VVR21_001985"
     CDS             1494..3365
                     /locus_tag="VVR21_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
                     /protein_id="HEU6055778.1"
                     /translation="MKIENKNVRRNFFWGDGRFYTTDIVNKRAGVMIKNVSKEEFTIT
                     LENGIRLSSNHFSAIVREEGDTRIQVSFVCPSIRLRLIFESRDDVLSKQLVLESSTEV
                     IKSVEVESFEFETEDNIFYPKRQDCIKEMANFSGYYVELGQPVYANSLFLGMEFPMSE
                     NKVDGRHYVSRYYLGTVVNQEKSLWSCIIGGACSYKKEEIQEAFFEYVEGIAQPSYFR
                     KQYNSWYDHMTDITEEGILKSFSEIRDGFENHGVHLDAYVVDDGWTNYQSVWEFNHKF
                     PNGLRNIKHLVNGFGSSLGLWIGPRGGYNGTEIIMSDWLEAHPELNIGSKNLISNDVN
                     VADFNYLNQMKKKMLEYQKEFDISYWKIDGWLLQPDKPDKSGPHGMYTMTAVYEFLIQ
                     LLIDLRKERGGKDCWLNLTSYVNPSPWFLQWVNSLWIQISQDVGFTENAGNDINRMIT
                     YRDSQYQEFLEKREIQLPMWSLYNHEPIYAVSANTWYMDHQMFASIPDFEAYLLFIST
                     RGNAFWEFHYSFDMFDEERWKANARAVKWIEENYQTLKYSKKIGGSPEKFEIYGYKCH
                     NQKTSTEILSLRNPAQIKQKIKIENLSIENFTRVIGDFTIQEDEIELAPYSIVILKK"
     gene            3387..5603
                     /locus_tag="VVR21_001986"
     CDS             3387..5603
                     /locus_tag="VVR21_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU6055779.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCAETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSGFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            5614..>8228
                     /locus_tag="VVR21_001987"
     CDS             5614..>8228
                     /locus_tag="VVR21_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEU6055780.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLITKGKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDNKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDKIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGDEV
                     VFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPFTP
                     GNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSANH
                     LNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSYSG
                     KHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQGK
                     YTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLPKRDGAARDFYEHMLEEAAKYVNPK
                     TGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWAND
                     IENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFMFK
                     NTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQGDR
                     QWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVIAH
                     PAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGVLK
                     TDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFVYN
                     YKVNENVKQTGKLKF"
BASE COUNT         2876 a         1070 c         1676 g         2606 t
ORIGIN      
        1 aaatgaatta acagtaccag cattactagg tcaatttact acaagtttta atactaatta
       61 taatggtcta ttttcagcta ttgttgtaat cgtattacca ccaatcattc tattcgcatt
      121 tacaagtaaa tacttcattg aagctttagg aggaggagca gtaaaaggat gaaacataca
      181 cttgaaacta tcaatagtag aactcagtgg tttagagaag caagatttgg gatgttcatt
      241 cattgggggt tatattctat tccaggaaaa ggggaatgga ttcgtagtca tcagaaatta
      301 tctattgaag attatgaacc atattttcga gcttttgatc ctaaggaata taaccctaga
      361 gaatgggcta aacaagcaaa agctgcaggg atgaagtata tggttttaac ggctaaacat
      421 catgatgggt tttgtttgtt tgattcaaaa tttacagatt ataaagcaac aaatacacct
      481 gcaggtagag atttagttaa agaatttgta gatgctgttc gagctgaagg tttaaaagta
      541 ggcttatatt ttagtttgat tgactggcac catcctgatt tccctaaata tgctgatcta
      601 aatcatccaa tgagaggaaa tgaagcctat cgagatgaga aaattaactt tgacagttat
      661 ttggagtatt tgcacaatca agttaaagaa attgtaactg gttatggtca gattgacata
      721 ttatggtttg attattctta tgaagacatg gtgggtgaaa aatggggagc ttcaaaatta
      781 atagacatgg ttcgtcatta tcagccaaac gttatcgtag ataatagatt agaaacatca
      841 ggtgaaggat tcggaagtat cgttacagat gaaattacct cttacgctgg agattttgtt
      901 agtccagagc aaattgttcc tcacgaaggt attcgaaact ttaaaggtga acctgttcct
      961 tgggaacttt gtctaactat gaataacaat tgggcttata atcctacaga ttatctatat
     1021 aagtctagtc aaactttgat aagaaagtta gtggaatgtg ttagtaaaaa cggaaatatg
     1081 attcttaatg taggcccaga tgctttggga agaattaatg attcaagtaa gaaaatatta
     1141 gataattttc atcgatggat gtctcgaaat ggtgaggcaa tttatggatg tagtggagat
     1201 gaaaatttac caaaaccaga ttggggatac tatactcgta atggaaatac ggtttatgct
     1261 catgtatttg aacaacctat aggtccttta gctcttcttg gtattagtaa agaaaacgta
     1321 aaaagaatga gctttcttca tgatggaagt gaggtgaaaa tttcagaaag ctggacgacc
     1381 aatgcctaca aaggaatttg ttttgcacag tttggagaag ttccacattt tacctatcca
     1441 ttaccagact tgattgatag cgtaatcaaa attgagttga gagagtagtt tatatgaaaa
     1501 ttgaaaataa aaatgtaaga cgtaatttct tttggggaga tggtcgattt tatactactg
     1561 atatcgtaaa caaacgggca ggagtaatga taaaaaatgt ttcgaaagaa gaatttacca
     1621 ttacattgga gaatggtata agactttctt caaatcattt ttcagcaatc gttagggaag
     1681 agggagatac gcgaattcag gtttcttttg tttgtccttc cattcgttta cgtttaatct
     1741 ttgaatcgag ggatgatgtt ctttcgaagc aattagtttt agaatcatct actgaggtta
     1801 ttaaatctgt agaggtagag agttttgagt ttgaaacaga agacaatatt ttctatccga
     1861 aaagacaaga ttgtattaag gaaatggcga atttttccgg ttattatgta gaattgggac
     1921 aacctgttta tgcgaattct ttattcttag gaatggaatt tccaatgtct gaaaacaagg
     1981 tagatggtag acactatgta tcaagatatt acttgggaac tgttgtaaat caagaaaaga
     2041 gtttgtggtc ttgtattatt gggggagcat gctcttataa aaaagaagag attcaagagg
     2101 cattttttga atatgttgaa ggaatagctc aacctagtta tttccgtaaa cagtataatt
     2161 cctggtatga ccatatgacc gatattacag aggaaggtat tctaaaaagt ttttctgaga
     2221 ttcgagatgg atttgaaaat catggagttc atttagatgc ttatgttgtt gatgatggtt
     2281 ggacaaacta tcaatcagtt tgggaattca atcataaatt cccaaatggt ttgagaaata
     2341 ttaaacatct tgtaaatgga tttggttcaa gcctaggatt gtggattggt ccccgaggtg
     2401 gttataatgg gacagaaatc attatgagtg attggttaga agcacatcca gagttaaata
     2461 ttggatctaa aaatttgatt tcaaatgatg taaacgtggc tgattttaac tatctcaatc
     2521 aaatgaagaa aaagatgttg gaatatcaaa aagaattcga tatcagctat tggaaaattg
     2581 atggttggtt acttcaacct gacaaacctg ataagagtgg accgcacggt atgtatacca
     2641 tgacagcggt ttatgagttc ttaattcaac tgttgataga tctaagaaag gagagaggag
     2701 gaaaagattg ttggttaaac ttgacttctt atgtaaatcc tagtccatgg tttttacagt
     2761 gggtcaatag tttatggatt caaatatctc aagatgtagg ctttacagag aatgcaggta
     2821 atgatatcaa tcgtatgatt acttaccgag atagtcagta tcaagaattt ttggaaaaac
     2881 gtgagataca gttacctatg tggtcgcttt ataatcatga accaatctat gctgtcagtg
     2941 caaatacctg gtacatggat catcaaatgt ttgcatcaat accagatttt gaagcttatc
     3001 tattatttat ttcaacaaga gggaatgctt tttgggagtt tcactattct tttgatatgt
     3061 ttgatgaaga acgctggaaa gccaatgctc gtgccgtcaa atggatagag gagaattatc
     3121 aaacactaaa atatagtaaa aaaataggag gaagtcctga aaaatttgaa atttatggtt
     3181 ataagtgtca caatcagaag acttctactg aaattctctc tctgagaaat cctgctcaga
     3241 ttaaacaaaa aataaaaata gagaatcttt cgatagagaa ttttaccaga gtaattggag
     3301 attttactat tcaagaagat gagatagaat tggcaccgta ctctatcgtg atactgaaga
     3361 aataaagaaa aaattgtgag gtagagatga cgatttatat taataaggac gagaccgttt
     3421 ttcatttggc aatgaaagat agtagttata tttttagaat tttagaaaat ggggaacttc
     3481 aacatctaca ttttgggaaa aggattcatg tcaaggaaaa ttataaccaa ttgatggcct
     3541 atgaaaaaag aggatttgaa gtatcttttt ctgaagaatt tgaggatatt caacagtcta
     3601 tgatacaaaa tgaatattct tcatatggga aaggagattt tcggcatcca gcctttcaag
     3661 ttcaaggaat gaatggtagt aggataacga cactaaaata tcaaggtttt gaacttgaaa
     3721 aagggaaaaa tcgtcttaac tctctacctt caacatttga tgatattggt cagtgtgcgg
     3781 aaacattaac gattatttta acagattcca tattagattt aactgttaga ctaaattaca
     3841 caatttttcc ggaatacaat gtcttagtta gaaatacgga atttttaaat aatagcaata
     3901 ataagttgac tcttttgaaa gcaatgagct tacagctaga tctacctgat agtcaatatg
     3961 actttattca attttctgga gcatggctga gggaacgtca gttatataga acttcgctta
     4021 gaccaggtat tcaagcaata gatagcttga gatactcatc aagtcctcag caaaatcctt
     4081 tctttatgct atcaaggagg gaaactacag agcatagtgg tgaggtttat ggttttaact
     4141 ttatctattc tggaaatttt caaaatatga ttgaagttga ccattttgac accgctagag
     4201 taacggtagg aataaatcca gtagaatttc gttttttatt aaatcctgcc gaaagttttg
     4261 tgacaccaga agcaattgtg atctattctg atcaagggat gaatcagatg agccaacaac
     4321 tatcagattt ttatcgacat catttagtta atcctaattt ttctcaagct agtcgtccta
     4381 taatactcaa tagttgggaa acattttatt ttgacttgag tacagaaaaa attttagatt
     4441 tagcaaaggc tgctaaagat ttagggatag aattatttgt actggatgat ggttggtttg
     4501 gtcataggaa agatgacaaa agttctctgg gtgattgggt aacagataga agtcgtcttc
     4561 ctgaaggtat tggatttctt gcagatgaaa ttcacaaaat aggtttacaa tttggtttgt
     4621 ggtttgagcc tgaaatgatt tctattgata gtgatttgta caagaatcat gccgattgga
     4681 ctatccattt gttagacaga gagaagtcag taggaagaaa tcaatatgtg ttggatttga
     4741 cgagacagga agttgttgat tatctttttg attctatttc taaaatcata atcaaaacaa
     4801 atctggatta tatcaaatgg gatatgaatc gtcatataac agatatttat agtattgaac
     4861 ttgattctga acagcagatg gaatttggtc atcgatatat cttaggtctt tatcagttat
     4921 tagatcgttt aataactaag ttcccttcag ttctatttga atcttgttct tcaggtggtg
     4981 gacgttttga tttaggactt atgtattatg caccgcaagc gtggacgagt gatgatacgg
     5041 acccgataga aagattgaaa attcagcatg gaacttctta tggatattct ccatcaatga
     5101 tgacagccca tgtttctatt tctccaaatg aacaaagtgg aagacaaacg agtttggaca
     5161 ctaggacaaa tgtagcttat tttagttctt tcggttatga attagatgtt acgagattgt
     5221 cggtagaaga aaaagaacaa gtgagagaac aaattcagtt ttataaaaaa tatcgttcat
     5281 tgtttcaata tggggatttc tataggataa acagtccttt tagttgtgat tctgctagtt
     5341 ggcaagttgt ttcaaaagat aaatgccaat cgattttatt gtatgctcaa ttgaatagta
     5401 agttgaatcc aggttataca agagtttatt ttagtggttt agataaagat aaatgctatt
     5461 ccgtctctgg atttgatgag ttcttttatg gagatgaatt aatgaatgct ggaataaaag
     5521 taagtttaag taatttagca ctttgtgttc cagaatatct tacaaaatta tttgttattg
     5581 aggaagttgt atgtaaatat tgaggaaata aaaatggaaa gtaaaaaaat agcaaaacag
     5641 attttaatag ctacggctgt tttaacaagt tttttaggaa gtaatttggt ttatgcagat
     5701 gtagttcaaa gtaattctaa taacagagct agtactgaaa ctgctagagt aacagggaat
     5761 aacttagaaa aacttattac taaaggtaaa gaaattgata aagagatgac atatctttca
     5821 gatatggatt ggtcttctgc aactcatggt gatatagata aaacaaaaac agtacaaaaa
     5881 gatgctccat ttacaacagg aaataaagga gagcatacta agatttcatt gcttacttct
     5941 gacaataaag ttaagtattt tgataaagga atagggacag tcgcagattc cccgtctgta
     6001 atcagctatg atattagtgg tcaaggattt gaaaaatttg aaacttatat aggaattgat
     6061 caaagtgcta atagttctag atcagaccac gcagtagtgg ataaaataga aatagatgga
     6121 aaggttgtct attctagtag tgtaactaat ccagaaggat tcagatataa tacccaggca
     6181 caatttatta gtgtgacaat tccacaaaac gctaaaaaaa tatccttaaa atcattcgca
     6241 ggagaacata catggggtga tgaagttgta tttgctgatg ctaaacttat taaaactgtt
     6301 agtactcaaa ctataactcc agatcttctt aataaaggaa ttaatggagg agtatatctt
     6361 tctgatttag aatgggttga tgctactcat ggtgatgacg ataaatcaaa aacagttcag
     6421 aaagataaac cgtttacacc tggtaataac gggtctaata ataaaataaa attactaatt
     6481 gacggtaagg aagtcgaatt taataaggga ttgggaactg tagcaagtaa cccgtctagt
     6541 ataaaatatg atgtttcggg tgctaatgtt acaagattta tttcctatgt cggaattgat
     6601 aggagtgcca atcatttaaa ttcagattac gcagatattc aaaaatttga agttgttgcg
     6661 gatggtaaag tcatttactc atcagattca aaatatccaa aaggaattaa gtatgataca
     6721 tcggcatttc tggttgatgt tgaaattccc aaagatacac agacaataga acttaaatca
     6781 tattcaggga aacatacatg ggctgacgaa ttggttttag gtggagcctt gtttatggca
     6841 aatggtaaat ttaagaatcc taatgattgg tcagaagttg ataaacgtcg tgaaattaat
     6901 aatgaacatc cgttacttat gatgccttta tatgctaacg gagaagagtt taaccaaggg
     6961 aaatatactt tttggggagg agatacatta acaggtaagt gggagaatat accagatgac
     7021 ttaaaaccat atactgttat acagttacat ccagatgatc ttcctaaaag agatggagct
     7081 gctagagatt tttatgaaca tatgttagaa gaagcagcga aatatgtaaa tcctaagact
     7141 ggaaaaaatg aaccaattcc agttattctg acggtttaca ctgctggtaa tatgccttat
     7201 tatacttcgg cacattggtt aagtaccagc tggattgata aaatgtatca aaaatatcca
     7261 aatttgcatg gtattttcag tacagagaat tattggattt gggcaaatga tattgaaaat
     7321 aaggcggcag attacttaaa agtatcagct aaaaatggag gatattttat atgggctgaa
     7381 caaaataatg gttctgcaat agaaaaagca tttggaaaaa acggtaagat agcatttcag
     7441 aaatctgttg ataagtactg gaagaacctt attttcatgt tcaaaaatac acctgctgct
     7501 gagggaaatg attcaactac agaaagttat atgaagggac tttggctttc aaatcatact
     7561 tatcaatggg gtggtttgat ggatacttgg aagtggtatg agacaggtaa atggaaactg
     7621 tttgcaagtg gtaatatcgg aaaaagtcaa ggagatagac aatggttgac tgaaccagag
     7681 tctatgctag gagaagaagc tttaggggtt taccttaatg gaggtgtagt ttataatttt
     7741 gaacacccag cttataccta tggtgtaaat aataaagaaa gcttactctt tagcgaagta
     7801 ataaaagaat tttttagata tgtaatagcg catccagcac catccaaaga aaaggtactt
     7861 gaggatacaa aagtattcat acatggagac tattcaaata aaggaaatgg taagttcttt
     7921 gtaaacgtaa atactgatag agaacaaact ccattataca tgactggtcg ttataatgtt
     7981 attccagcta ttccaggtgt tttaaaaaca gataaattga aagagtctgt ttctggtagc
     8041 cgtattcaga ttaaggaaat cacttctcca gaatttagct ctactcaggc tagaaaagaa
     8101 tacttaaata agctgtatcc tatgaattat gaaggagata tctttgctca gaaattagat
     8161 aatagatggt ttgtctataa ttataaggta aatgagaatg ttaaacagac tgggaaatta
     8221 aaatttaa
//
LOCUS       DAVHSI010000066         7967 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.067, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000066 DAVHSI010000000
VERSION     DAVHSI010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.067"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            91..1200
                     /locus_tag="VVR21_001988"
     CDS             91..1200
                     /locus_tag="VVR21_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6055781.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            1230..4562
                     /locus_tag="VVR21_001989"
     CDS             1230..4562
                     /locus_tag="VVR21_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU6055782.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVTYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYFRADPRDGE
                     GRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLNELDFRV
                     RMVLDTVYSYRKLESWQNLTTVTSETIQKNLSPLLFDEDKEDEMARRFDLWLLHIQLG
                     QLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLSDLEKIR
                     LAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLD
                     EESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRES
                     ANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQ
                     LPVLRNIVQIIELINNRAGEAA"
     gene            4806..4907
                     /locus_tag="VVR21_001990"
                     /pseudo
     CDS             4806..4907
                     /locus_tag="VVR21_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5104..5574)
                     /locus_tag="VVR21_001991"
     CDS             complement(5104..5574)
                     /locus_tag="VVR21_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU6055783.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(5591..7864)
                     /locus_tag="VVR21_001992"
     CDS             complement(5591..7864)
                     /locus_tag="VVR21_001992"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU6055784.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2530 a         1317 c         1680 g         2440 t
ORIGIN      
        1 gtcatattaa agaaaatcaa tgatttagaa aaagaaattc aagctggctt ggctgaattg
       61 gaaaaattac tcaagtaggg aggtggctgt atgaaaaaag tgaagttggg ggaagtctta
      121 tctctaaaaa aaggcaagaa agccactgta cttgctgaac aaacaactct aagccaacgt
      181 tatattcaaa tagatgattt aagaaataat aataatttaa aattcactga aagtttaaat
      241 atgactgaag cactcccaga tgatattctg atagcatggg atggagctaa tgcaggaaca
      301 gttggttatg gattatcggg agctgttggt agtacaatta cggtcttaaa aaagaatgag
      361 cgatacaaag aaaaaattat atcagattac ttgggagtct ttttggaaag taaatcgcag
      421 tatttacgag atcattcaac aggtgcaaca attcctcatt taaacaagaa tatattactt
      481 gatttacaat tagaattgct aggtatcgaa gaacaagaga acattatctg tattcttaat
      541 acgattaaaa ggcttattac taaaagaaaa ttgcagttag atgaactaaa cttgctcgtc
      601 aaatcccgat ttaacgagat gtttggggaa aataaaatat ttgaaagcat tgataactta
      661 tttgatatta tagatggtga taggggcaaa aattatccta aatcagatga gttgtttagt
      721 gaggagtact gtttattttt aaatacaaag aatgttacta aaaacggatt ttcattcgat
      781 acaaagcaat ttatcactaa aacaaaggat aaattacttc gaaaaggcaa acttgagcgt
      841 tatgatatag tcttgacaac aagaggtact gttggaaatg tagcgtacta cgatgaatta
      901 ataaaatata aacatttacg tataaattca ggtatggtaa tattacgtcc caagacacca
      961 aatctaaatc agaaatttat tatccatgtt ttaaggaata ataattatag tcgagtgata
     1021 tcaggaagtg ctcagcctca gttaccaatt acaaaattaa aaaaaatact tctccccctc
     1081 cccccactag ccctccaaaa tgagttcgca gactttgtag tccaggtcga caaatcacaa
     1141 tttgcttgtg agatagctat aaaagtgtgg agaaatagct tgaaatttag tataatatag
     1201 ctaaactatt tgtttaaagt gagaaaaaaa tgggaaattt tagctttctt ttaaaaaatg
     1261 acgaatatga atctttttca aaaccttgca ttgaagctga aaatatgatt gctacatcaa
     1321 ctgtggctac tgcctttatg gcgcgtcgtg ctttagagca ggctgtccat tggatatata
     1381 gtcacgattc atatttagaa gctccctatc gtgctactct atcttcttta gtatgggatg
     1441 atgattttag ggatatcgta gattctgaac tccacaagca gatagttctg ttgattcggt
     1501 ggggaaacca tgctgctcat ggtggtgaaa ttaaggaacg agaagcgatt ttagctttac
     1561 atcatttgta tcagtttgtt aattttatcg attattgtta cagcaatgaa tttgtggagc
     1621 gttattttga tgagaagtgc ttaccacttt cagcaaacat caaataccga gaaactccac
     1681 aatctatgat aaagttacaa gacagtttac cagaactgcc tgattttcat gaacagatgg
     1741 ctgctcagtc cgtagaagtt caagagactt atactgaaaa acgtgagact gcagcgcaac
     1801 ggcaagatgt gcctttccat attgatcaat tatctgaggc agagacaaga aagctcttta
     1861 ttgatatcga tctccgttta gcaggatgga tatttgaaga aaactgtcgt gttgagatag
     1921 ccgttgatgg tctcaagcac ggttcaggaa ttggttactg tgactatgta ctttatggta
     1981 aaaatgggaa aattttagcg attgtggagg ctaaaaaagc ctctgtcaat ccagaagtag
     2041 gggaagtaca ggtcaaagaa tatgctgaag ctttggagaa acatatcggc tatcagccaa
     2101 tttgctttat tacaaatggg ttgaagcact atatacttga tggtccgaac cgccgccaga
     2161 ttgcaggctt ttactctcaa gaagaattgc aattagtgat ggatagacgt catcttcaaa
     2221 aaccacttga ggatatttct agtaaaatta gggacgatat ttccgggcgt cactaccaaa
     2281 aacatgccat tgcaagcgtt tgtgaagctt tctctaatca tcgtagacag gcacttttgg
     2341 ttatggcaac tggggctggg aaaactcgta cagcagtttc tctagttgat atcttatcac
     2401 gtcataactg ggtaaaaaac gttctcttct tagccgatag aacttccttg gttaagcaag
     2461 cctatgattc gtttagaaaa ttactcccag atctttccgt ttgtaacttc ttagaagata
     2521 aagaaggagc tcaatcaagt cgcatggtct tttcaactta tccgaccatg attggagcga
     2581 ttagtggtca agaagaagta aatcaacgcc ctttcactgt tgggcatttt gaccttatca
     2641 taattgacga atctcaccgt tctatttatc agaaatacaa gtccattttt gattattttg
     2701 atgcaagaat tgtaggctta acagctactc cgcgtcaaga tttagataaa aacacctatg
     2761 gattctttaa tttggagaat ggggttccaa catatgcata tgatttggaa gaggctgtta
     2821 aagacggata tttagtaacc tatcattcta tcgaaaccaa actgaaacta cctacggatg
     2881 gtctacatta tgatgatttg tccgaagaag aaaaggaaca ttttgatagc aaatttgaag
     2941 acgatagctg tgaaaaagat attgatggga gtgtatttaa ttcctttgtt ttcaataaaa
     3001 gtacagtaga aattgtttta aatgaactca tgacaagagg aattcagaca gcctcgggtg
     3061 atgaaattgg taaaactatt atttttgcta aaaatcatga tcatgcggaa tatatcagag
     3121 gtatttttaa caaccgctat cctgaaaaag ggagcgacta tgctcaggtg attgattata
     3181 gtattaagca ttatcagacc ttgattgatg attttaaaat taaggagaag tatcctcaaa
     3241 ttgcgatttc tgtcgatatg ttagatacag gtattgatgt accagaggtt gttaatttag
     3301 tcttcttcaa gaaagtacgc tctaaaacta agttttggca gatgattggt cgaggaaccc
     3361 gtctatgtaa agatttattt ggacctgagc aggataagga aaacttcttg gtatttgatt
     3421 attttcgtgc agatccaaga gatggagagg gtcgtcacat tgtttcgttg actcagcgtt
     3481 tatttaatat caaagtggac ttgattcgag aacttcaggg actccaatac caagaagatc
     3541 agtttgcgag agcataccgt cagcagcttg tctcggaact tcaaggtcgt atagagagct
     3601 taaatgagtt ggacttcagg gttcgtatgg ttttagatac agtttatagc tataggaaat
     3661 tggaaagttg gcagaatcta actactgtta caagtgaaac cattcaaaaa aatctctctc
     3721 cgcttttatt tgatgaagat aaagaagatg agatggccag gagatttgat ttgtggttgc
     3781 ttcatattca gttggggcaa ctgacagcta aatcttccac tgttcatatt tcccaagtga
     3841 tgaagacggc tagagctctt tctgctattg gcaatatccc gcaggttttt gagcaggctg
     3901 aaattatcag gaaagtacag gagcctgaat tttggaaaga agttaacttg tctgatttgg
     3961 aaaaaattcg tcttgctatt cgagatttat tacagttttt ggataaaaca gaccgtaaac
     4021 cctactatgt taactttgaa gatcgtatac tctccactgt tcacgagacc acagcatttt
     4081 tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga gcattatttg aaaactcatc
     4141 tggatgagga gtccatttct aagctatacc ataataaaaa gttgacatct gatgatatgc
     4201 ttgcacttga aaaattgctc tgggaaaaat taggtagtaa agcagactac caaagtcatt
     4261 atgaaaataa ggcaattccg agattggttc gtgagattat tggcttagat agagagtctg
     4321 ccaatcgtat tttttctaaa tttttgtcgg atgagaatct taatgccagg cagatttcat
     4381 ttgtaaaatt gattgtagac tacattgtag aaaatggttt tttagagacg aaagtgttaa
     4441 cgcaagagcc gtttaaatct tatggttctg ttcaactact cttccaacac caactaccag
     4501 tacttcgtaa tattgttcaa atcattgaac ttatcaataa tcgagctgga gaagcggctt
     4561 aaattctaaa gtgattgcca tgctgagact catttaaaat taaaaagagt agaaatttat
     4621 gctatatatg agaagtttta ttaggaagaa tgtcatcgtt tttctagaat acagtatcag
     4681 ttgttaagtg gctgataaat ttcaaagtag atacttgtac cacgatgttt gttgatcgag
     4741 ttattaacaa aagagctact ttgattttaa agaaatagaa aacaaaaagc cgagcaagaa
     4801 ttcaattgca ggagaaaatg aaataatact caatgaaaat caaagagcaa actaggaaac
     4861 tagctgcagg ctgctcaaaa cactgttttg aggttgtaga tgaaactgac gaagtcagta
     4921 accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat
     4981 tttcctagga taaagcaaaa cgcatagtat caagggtttt caacacttga tactatgcgt
     5041 tttctgatgt taaagacttt ctaccagttt tttttaagca taattgttag ttgtagtcat
     5101 ttattattct tcaaagaaaa atggtggggc gaattttttc agttcttcaa agcacttttg
     5161 agcagtatct gcatcttcac agatgataag acagacatca ttaccacaaa gggtagcgat
     5221 agcgtcaggg aagctcaaag tatcaatgat agaaccaaag gattgagcca gtccaggaag
     5281 ggtttttagt aggacttggt gttgaactgg gcgcatccag acaagggcgt cttccatgta
     5341 gagttcgaga cgtttttccc attttgagat ggaaccattg ttaagaacat aataagcgct
     5401 atcttcttcg cggacttttg ataggttcat atttttgatg tcgcgtgaga gggttgcctg
     5461 ggttacttga atgtcgttct tagcaagaag ggcttgcaac tcagcctgtg tatgaatctt
     5521 gttttttgtg ataagagcgc gtataagttg gtggcggtgt tctgatttat tcataataat
     5581 gtaactcctt ttagcaaggt aaggtaagca tggactgagc gaggtcgaca gtcaagtggt
     5641 agtctgtatt gtcacggatg gtgatttcaa agtcagtagt atagaggact aaacggagag
     5701 tgtctccttc ttttagcttg taaatagttg gctgcagttc aaattgaacg tccatccatt
     5761 catctgcagt aatatcctct actaacagta aatcatttct attttgtaaa ttaaggtaac
     5821 cttttgtcac gactcgttgt gcctctggtc taaatggcaa ttcacagaga ttttccaaca
     5881 tgtgatagcg accgttgtca atggttctag cacttaaaat agctggataa ggttgtaggt
     5941 atttcttttg cccaaattct agcagttggg cagataagag ccccttgttt gtactggatt
     6001 tgatacgaag attgagctga gcgcgaccgt ttaggtggag atctttagtc acaggaaggt
     6061 taatagtaat ctgattggct ttcccttgat agagctctgt attgaaggtt tggtatgtct
     6121 taccatagcg ctcaaaatcc ttatctgggt actggttttg aatagcttgc tcttcttgac
     6181 caagtgagaa ggtttcacag ttttcttgcc caccgaagtt atcaagtgat aaccaagtct
     6241 gtggagctgt attgtcctgc cagataacag taggaagttg aaagtctgtt tcctgtccta
     6301 gtaatttctt ggtcaataag gcatttatgg actcacggaa gtcaattgat tgccaattgt
     6361 tcatgtaaac atgggcacca ttatggaaaa agagatgctt gtgtatatga gtaggaagag
     6421 catggaacat ctggtaaaca tgaagtggtt tgacattcca atcctgagaa ccatgagtaa
     6481 agacaacctc tgcctttact ttatgggcat tgagcagata attgcggtca tgccaaaact
     6541 gattgtagtc cccagttttt cggtctagct gagctttcac tttttctaag tcagcttggt
     6601 gagcttcatt gccacggata tagtcgccag ctaagagatt acgagaatag gttaactcag
     6661 caagggagtc aaagtcctca cctggataac cacctgggct agtcaccaga ccgttttcac
     6721 ggtagtagtt gtaccatgat gaaattcctg cctcggcaat gataacttct aaaccatcga
     6781 ctcctgtagt cgcaagacca ttggacatgg tacctagata ggaaagtcct gttgtagcaa
     6841 cttttccgtt tgaccaatca gccttgactt gacgctggcg cgtgtgatca gtaaaggcac
     6901 ggcaacggcc gttaagccaa tcgatgacat ttttataagc ctcgatttgc tggtagtctc
     6961 cattagtcat gaaacctgtc gagtctttgg taccaacacc tgagacatag agattggcaa
     7021 agcctctcgg aaggaagtag tcgtttagtg tatagctaga gttgatgtga gttagctttt
     7081 cctcagcctc tgctataagc tcagctttac cttggggttg gacgagattt agttgaggtt
     7141 tctctagctc aatcttgtga ggaagcttaa cctcaagctc gccctccatc ttgtagagag
     7201 ccttgtcact agccttgtca ttggttccct gatgataagg gctggctgtc atgatggcag
     7261 ggatttttcc atcaaaacga gggcgaataa tgctaacctt tactaggtct gatagccctt
     7321 tttggtcagt atcgacacga gactcaacgt aaacgacttc acgaatgaca tcctggttag
     7381 aaaaagtagc caaactcttg ccgttaaagt agtggtagtc attatcctcc ggaataagac
     7441 catcactaac aagttggtct ataagagtat ttcctttttt ggtgcgagta ttgagtaact
     7501 gatagagatt ttcaatcaag tcaccatata taatgggaaa tccagtttct ttacgaaaaa
     7561 cgtcactatc ttcgaagtca accaaataag aaaagcctaa aagttgaaaa gcaacagtat
     7621 aaaaaatatc tgctgtcagt tcatcttctg attgaaaaaa tgtcagcagg tctgtttttt
     7681 tatcagctgc taggatagaa agtgggtagt tggtgtcttg ataagtgaaa aagaaacgac
     7741 gtaaaaaggt ttcaagtgag tctttgtgat tggctgtatt ttgtaaatca aagccacatt
     7801 tttttagttc agataagaca ttttcttttg gaaaattgat ataactatat tgattaaaac
     7861 gcatagaacc tccatataga atgacagtta aggttattat atcaaaaaaa aagcagaaag
     7921 ggaattgtta acttcaaaag gaaataatcc aataaaaatg aataaag
//
LOCUS       DAVHSI010000067         7002 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.068, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000067 DAVHSI010000000
VERSION     DAVHSI010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.068"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            39..3140
                     /locus_tag="VVR21_001993"
     CDS             39..3140
                     /locus_tag="VVR21_001993"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU6055785.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIILYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDLFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVRKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSEQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            3222..4229
                     /gene="pfkA"
                     /locus_tag="VVR21_001994"
     CDS             3222..4229
                     /gene="pfkA"
                     /locus_tag="VVR21_001994"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU6055786.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4288..5793
                     /gene="pyk"
                     /locus_tag="VVR21_001995"
     CDS             4288..5793
                     /gene="pyk"
                     /locus_tag="VVR21_001995"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU6055787.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         2099 a         1232 c         1551 g         2120 t
ORIGIN      
        1 ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa ctagatacaa
       61 aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg agagcagcta
      121 aagaatacgg ctacactcat ttggctatga tggatattga caatctttat ggcgctttcg
      181 actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt gaaatgacag
      241 tgtttgtaga tgatcaggaa gtgaatttgc gctttttagc tctatctagt gtgggctatc
      301 agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg tcagtcctgt
      361 cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt gagtcgttag
      421 aactaggctg tgattactat ataggggttt atccagaaac actagcaagc gaatttcatc
      481 atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga gaagttcttc
      541 aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg cgttcgagac
      601 aagatgtctt tatatcagca agttctttag agaaactatt ccaagagcgt tttccgcaag
      661 ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat actagtctga
      721 aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag cgtgctgaac
      781 tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta gaccaagaat
      841 tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg gatttgttgc
      901 gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca gtaggcagtt
      961 tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat ctgatttttg
     1021 aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat atcccagata
     1081 tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa catgcggcac
     1141 aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc ttgaaacgct
     1201 ttggtgtgcc agagtatgaa ttatctgcaa ttactaagaa aatcagtttt cgtgacaatc
     1261 ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt aagttagaat
     1321 accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa acctctgtcc
     1381 atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct ctaaagtatg
     1441 gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc ggacttttga
     1501 agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa gagttgcttg
     1561 ctgaaataga aggtattcat ctgaaaattg aagaaatcga tttagaagac aaagaaacgt
     1621 tagctttatt tgcctctggt aatacaaaag gtatctttca atttgagcaa ccaggtgcca
     1681 ttcgtctgct taagcgtgtg caaccagtct gttttgaaga tgtcgtcgcg actacttctc
     1741 taaatcgacc gggtgctagt gactatatca ataattttgt ggcaagaaag catgggcagg
     1801 aagaagtgac tgttctggat ccagtactgg aggatatttt ggctccaacc tacggcataa
     1861 tactctatca ggagcaggtt atgcaggttg cccagcgact tgccggattt agtcttggga
     1921 aagccgatat tttgcgtcgg gctatgggga aaaaggatgc ctctgccatg catgagatga
     1981 gggcttcctt tattcaaggt tcattagaag ctggtcatac tgtggaaaaa gcagagcagg
     2041 tctttgatgt tatggagaag tttgcaggct atggttttaa caggtcacac gcctatgcct
     2101 actcagcctt ggccttccag ttggcttatt ttaaaacaca ttatccagcc atattttatc
     2161 agattatgtt gaattctgcc aacagtgatt atgtaacaga tgccttagaa gcaggttttg
     2221 aagtagcccc attgtccatc aatactattc cctatcacga taaaattgcc aacaagtcta
     2281 tctatatagg tttgaaatcg attaaggggc tcagcaagga cttggcgctt tggattattg
     2341 aacatagacc ttattctaat attgaagatt ttatagctaa attacctgag aattatctga
     2401 aacttcctct gctagaacct ttggtaaaag ttggcctttt tgatttattt gaaaaaaatc
     2461 gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag ttgggaagtt
     2521 tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa caagaaaaat
     2581 tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta caagctattg
     2641 caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat agctatgcta
     2701 ttattttggt tgaagttcgg aaaataaaag tgattcgtac caaaaagggt gaaaatatgg
     2761 ccttcttaca ggcagatgat agtaagaaaa aattggatgt cactctcttt tcagacttat
     2821 atcgtcaggt tggacaggaa ataaaagagg gagccttcta ctatgtaaaa ggaaaaatac
     2881 aatcacgtga tggccgtctg caaatgattg cacaagaaat aagagaagca gttgctgaac
     2941 gcttttggat tcaggttaaa aatcatgact cggagcaaga gatgtcacgt attttagacc
     3001 agtataaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa accatcgttt
     3061 ctccccatca ttttgtagct aaatctgatg aattagaggc gaaattgaat ggaatagtta
     3121 tgaaaacgat ttatcgctaa aattacggaa aatagaagaa ttttcaacgt aaatgtggta
     3181 taatcagtaa gaatgttaaa agaaaaagga gcataaccaa tatgaaacgt attgctgttt
     3241 tgactagtgg tggagacgcc cctggtatga acgctgccat ccgtgcagtt gttcgtcaag
     3301 caatttcaga aggaatggaa gtgtttggta tctatgacgg atatgctggt atggttgccg
     3361 gtgaaattca tcccctagat gcagcttcag taggagacat catttctcgt ggtggtactt
     3421 ttcttcactc agctcgttat ccagagttcg ctcaacttga agggcaactt aaagggattg
     3481 agcaattgaa aaaacacgga attgaaggtg tagttgttat cggtggtgac ggatcttacc
     3541 acggcgctat gcgtttgact gaacatggct tcccagctat tggtcttcca ggtacaatcg
     3601 ataacgatat cgttggtact gactttacaa tcggttttga cacagcggtt actactgcca
     3661 tggacgctat tgataagatt cgtgatacat catcaagtca ccgtcgtact tttgtaatcg
     3721 aagttatggg acgtaacgct ggtgatatcg ctctttgggc tggtattgca actggtgctg
     3781 atgaaatcat catccctgaa gcagacttca agatggaaga tatcgtagca agcatcaaag
     3841 ctggttatga atgtggtaaa aaacacaata tcatcgtctt agctgaaggt gtgatgtcag
     3901 cggctgaatt tggtcaaaaa cttaaagaag ctggagatac aagcgacctt cgtgtaacag
     3961 aacttggaca tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt ttggcgtcac
     4021 gtatgggtgc acatgctgtt aaacttctta aagaaggtat cggtggtgtt gcggttggta
     4081 ttcgtaacga aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa ggggcattgt
     4141 ttagccttac tgcagaaggt aagattgtgg ttaacaaccc acacaaagcc gatattgagc
     4201 tatctagctt gaataagagc ttgtcataat ttacaattta gttaataaga ccaaaaaggt
     4261 catatatata aaggagtcac aaaaatcatg aacaaacgtg taaaaatcgt tgcaactttg
     4321 ggtcctgcgg tagaaatccg tggtggtaaa aaattcggtg aggacggata ctggggtgaa
     4381 aaacttgatg ttgaagcttc agctaaaaac attgctaaat tgattgaagc tggtgctaac
     4441 acattccgat tcaacttctc acacggcgac caccaagaac aaggtgagcg tatggcaact
     4501 gttaaacttg cggaaaaaat tgcaggtaaa aaagttggtt tccttcttga tacaaaagga
     4561 cctgaaatcc gtacagaatt gttcgaaggt gaagctaaag aatattcata caaaactggt
     4621 gaaaaaattc gtgttgcaac taaacaagga atcaaatcaa ctcgtgaagt gattgcgttg
     4681 aacgttgctg gtgctcttga tatctatgat gatgttgaag ttggtcgtca agttttggtt
     4741 gacgatggta aacttggtct tcgtgtggtt gctaaagatg atgaaactcg tgaatttgaa
     4801 gttgaagttg aaaacgatgg tatcatcgct aaacaaaaag gtgtgaacat ccctaacact
     4861 aaaattcctt tcccagctct tgctgaacgc gataacgacg atatccgttt cggtcttgaa
     4921 caaggtatca acttcatcgc aatttcattc gtacgtactg caaaagatgt gaacgaagtt
     4981 cgtgcaatct gtgaagaaac tggaaacgga catgttcaat tgttcgctaa aatcgaaaac
     5041 caacaaggta tcgataactt agacgaaatc atcgaagcag ctgatggtat tatgattgct
     5101 cgtggtgata tgggtatcga agtaccgttc gaaatggttc cagtttatca aaaaatgatt
     5161 atcaagaaag tcaatgctgc aggtaaagtt gttatcactg caacaaacat gcttgaaaca
     5221 atgactgaaa aaccacgtgc aactcgttca gaagtatcag acgtattcaa cgctgttatc
     5281 gacggaactg acgctacaat gctgtcaggc gagtctgcaa acggtaaata cccactcgag
     5341 tcagtaacta caatggctac aatcgacaag aacgctcaag ctcttcttaa tgaatacgga
     5401 cgtcttgatt cagattcatt tgagcgtaac tctaagacag aagtaatggc ttctgctgtt
     5461 aaagatgcta ctagctcaat ggatatcaaa ttggttgtaa ctcttactaa gacaggtcat
     5521 actgcacgtt tgatttctaa ataccgtcca aatgctgaca tcttagcatt gacatttgac
     5581 gaattgacag aacgtggctt gatgttgaac tggggtgtta tcccaatgtt gacagatgct
     5641 ccatcttcaa ctgacgatat gttcgaaatc gctgaacgta aagcggtaga agcaggtctc
     5701 gttgagtcag gcgatgatat cgttatcgtt gctggtgtgc cagtaggaga agctgttcgc
     5761 acaaacacaa tgcgtatccg cacagtacgt taagaaaaat ataaaaacct atcatatcca
     5821 gctttagagc ttgtgtgata ggctttttgt atagagggta agaaataggc aaaactttca
     5881 taatggattg atactcttcg aaaatcaaat tcaaaccacg tcagcgtcgc cttaccgtat
     5941 atatgttact gacttcgtca gttctatcta caacctcaaa gcagtgcttt gagcaacctg
     6001 cggctagctt cctagtttgc tctttgattt tcattgagta tgaaataaga tatgcacaaa
     6061 ttgattagga aattcaaatg aatttctaca aatgttttag caatcgtaat gtacttgtct
     6121 agattcgatc tgatatattt tcgatttaat gatatggtat ttaaaacctc caaagtagct
     6181 tgctccattc ttttacttac gtgagtgtag atgttattta ctgttttagc gtttttgtgt
     6241 tccactctaa ccattatagc attcttctca gctagtgtac taaggagtgt gtgcctgaaa
     6301 atatgggaac taaggggctg gtttatcggt ttctctagtt tagtatttgc cttttgcaaa
     6361 gtgatgttaa atgcctttct ctaaatttac atatcactat tgtttaacaa aatctaatct
     6421 actttaggtc acttattctt tttttgaaat gtagaatgaa ctttttcaaa gtttttcgaa
     6481 tcttttaaaa tctgtttgtt ttatatcgcc attctccccc ttttttaatt ctccctatat
     6541 agcctgacaa ctttcccgat ggtattatag tcaatctgtg gggtattctt gataaatagg
     6601 tagtcgctgt ttcttatctt tggctccatg gacttgctga cgacataagc gattgggtcg
     6661 tagtcgtctg ggataatgga aactccatat ctaaatcgtt gtcctgcatc gagcggctat
     6721 ctgcagagat aaactaccta acacgagagt aagtagtctg tctgtagtcg tccagtctga
     6781 tgatttttac gatacttcgt ttttctgctc atacagttgc ctctcggcat aggtcaggac
     6841 tttaccttgt ctgggtggta cccgttggtc gtagatagat tggatatcgc taggagaatc
     6901 cttttgaact ggaggaaaga gggcatcaat caagctactg aatactttaa ctaagtcaaa
     6961 tatagtattt ttcttagtag acctaaccct tttttcataa tt
//
LOCUS       DAVHSI010000068         6946 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.069, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000068 DAVHSI010000000
VERSION     DAVHSI010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.069"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            143..1180
                     /locus_tag="VVR21_001996"
     CDS             143..1180
                     /locus_tag="VVR21_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU6055788.1"
                     /translation="MFTKKTLLITGGTGSFGNAVLKRFLGTDISEVRIFSRDEKKQDD
                     MRHEFQAKMPEVADKIRFYLGDVRDLASVKNAMIGVDYVFHAAALKQVPSCEFFPVEA
                     VKTNVLGTENILTAAIEAGVKQVICLSTDKAAYPVNAMGTSKAMMEKIAVAKSRTVEE
                     DQTKVCVTRYGNVLCSRGSVIPLWIDQIKQGNPITITEPSMTRFIMSLEEAVDLVLFA
                     FEKGKTGDILVQKAPACTIEVLAQAVTELFAPNQDIKVIGIRHGEKMYETLLTTEECT
                     NAIDLGGFYRVPSDNRDLNYDKYFNEGDAKRNPLIEFNSSNTELWNVEQVKEKLLLLP
                     YIREELASLNQ"
     gene            1189..2400
                     /locus_tag="VVR21_001997"
     CDS             1189..2400
                     /locus_tag="VVR21_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU6055789.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQYHKVIAVDVIPEKVELINRRQSP
                     IKDDDIETYLVEKELDLVATLDGNEAYRDADFVIIAVPTNYDSKKNYFDTSVVEAVIE
                     QIIAVNLKATIVIKSTIPVGYTESLRTRFGQFKILFSPEFLRESKALYDNLYPSRIIV
                     GADLRDTEQVVQAERFATLLQEGSLKPDVETLIMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTKSIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDSKQLLANYHDVPQ
                     NMMTAIVESNRTRKYFIADRILKNALELSDGNQTIIVGVYRLTMKSGSDNFRQSSIQG
                     VIKCLKAKGVEVIIYEPTLEDHSFFFGNQVVNDLEVFKSSSQVIVANRMEKSLYDVLE
                     KVYTRDIFQRD"
     gene            2419..3648
                     /gene="cps4K"
                     /locus_tag="VVR21_001998"
     CDS             2419..3648
                     /gene="cps4K"
                     /locus_tag="VVR21_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4K"
                     /protein_id="HEU6055790.1"
                     /translation="MPLKILVTGSKGFVGKNLICTLEALKDGRDRTRPNLEIGEIFQY
                     DRDTDPILLDEYCKKADFVFHLAGVNRPQNPDEFMEGNYGFSSRLLEILEKYENTCPV
                     LLSSSTQASLEGRFSNSIYGQSKLVGEELFFEYGKKTGAPVLVYRFPNLYGKWCRPNY
                     NSAVATFCHNLAHDLPIQVNDPSVELELLYIDDLIQECLTALEGNPHRCNLDGLQILP
                     SPSGNYCYVPTTHRATLGEIVSLLETFKKQPNSLVMPEIPQGSFKKKLYSTYLSYLPV
                     DKFKFPLKMNIDERGSFTELLKTENKGQFSVNISKPGITKGQHWHHSKWEFFMVVSGR
                     ALIQERRIGLDENGQEYPILNFEVSGDKIEAIHMIPGYAHNIINLSDTENLVTVMWAN
                     ESFDPRHPDTFFEQVEK"
     gene            3649..4833
                     /gene="cps4L"
                     /locus_tag="VVR21_001999"
     CDS             3649..4833
                     /gene="cps4L"
                     /locus_tag="VVR21_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4L"
                     /protein_id="HEU6055791.1"
                     /translation="MKIKTDYSDIHFKDNGKLKLLIIVGTRPEIIRLSSVITKCRKYF
                     DVILAHTGQNYDYNLNGIFFDNLGLDTPDVYMDAVGDDLGATVGNIINTSYKLMNQIK
                     PDALLILGDTNSCLSAIAAKRLHIPIFHMEAGNRCKDECLPEETNRRIVDIISDVNLA
                     YSEHARKYLHECGLPKERTYVTGSPMAEVLHKNLSAIESSDIHERLGLKKGGYILLSA
                     HREENIDTDKNFISLFTAINQLAEKYNMPILYSCHPRSKKRLQESGFKLDKRVIQHEP
                     LGFHDYNCLQMNAFVVVSDSGTLPEESSFFTSQGYPFPAVCIRTSTERPESLDKAGFI
                     LAGIDENSLLQAVETAVSLAEDEDFGLPVPDYVEENVSTKVVKIIQSYTGIVDKIVWR
                     KS"
     gene            complement(5028..5153)
                     /locus_tag="VVR21_002000"
                     /pseudo
     CDS             complement(5028..5153)
                     /locus_tag="VVR21_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5229..5414
                     /locus_tag="VVR21_002001"
     CDS             5229..5414
                     /locus_tag="VVR21_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055792.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            5395..5745
                     /gene="tnpB"
                     /locus_tag="VVR21_002002"
     CDS             5395..5745
                     /gene="tnpB"
                     /locus_tag="VVR21_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6055793.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKSFS
                     ITPKINSSESRDFY"
     gene            5810..6004
                     /locus_tag="VVR21_002003"
     CDS             5810..6004
                     /locus_tag="VVR21_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055794.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            5991..6296
                     /locus_tag="VVR21_002004"
     CDS             5991..6296
                     /locus_tag="VVR21_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEU6055795.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEERICPDC
                     QGDLKEIGGSLQGQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            6312..6518
                     /locus_tag="VVR21_002005"
                     /pseudo
     CDS             6312..6518
                     /locus_tag="VVR21_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            6594..6946
                     /locus_tag="VVR21_002006"
                     /pseudo
     CDS             6594..6946
                     /locus_tag="VVR21_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2184 a         1128 c         1478 g         2156 t
ORIGIN      
        1 ttttggataa ggtgtatgtt gaaattctca ccaatattat cagtcagaaa aatattgtag
       61 tgcgttattt ttcatgttgt taagctttaa atttatttaa aaagcattat gttgaacatc
      121 attatagata ggagtaataa ctatgtttac aaagaaaact ctccttatta caggggggac
      181 aggttcattc gggaatgcag ttctcaaacg atttttggga acagatattt cggaggtacg
      241 tatcttttca agagatgaga agaaacagga tgatatgcgt catgaatttc aagcaaaaat
      301 gccagaagta gctgataaga tacgttttta cttaggagat gtgcgtgatt tagcttctgt
      361 taaaaatgct atgatcggtg tggattacgt atttcatgct gctgcattaa aacaagtccc
      421 ttcttgtgaa tttttccctg tggaagcagt caaaactaac gttctaggaa ctgaaaatat
      481 tctcactgca gctatagaag ctggagtaaa acaagtcatc tgcctttcta cagataaggc
      541 agcctatcct gttaatgcga tgggaacctc taaggctatg atggaaaaga ttgctgttgc
      601 taagtcaagg acggtagaag aagatcagac aaaagtctgt gtaactcgct acggcaatgt
      661 tctatgtagt cgtggttctg tgattcccct atggattgat caaataaagc aagggaatcc
      721 tataacgatt acggaaccta gtatgactcg ttttattatg tccttagaag aagcggtaga
      781 cctagttctg tttgcttttg aaaaaggaaa aacaggagat atcctagtac agaaagcacc
      841 agcatgtacc attgaagtgt tggcgcaagc tgttacggaa ctttttgcac ctaatcaaga
      901 tattaaagta atcgggattc gccacggtga aaagatgtat gaaacgttgt tgactactga
      961 agaatgtacg aatgccattg atttaggcgg cttttatcgt gtgcctagcg ataatcgaga
     1021 tcttaactat gataagtatt tcaacgaagg ggatgccaaa cgcaatccct taatagagtt
     1081 taacagtagt aatacagaac tctggaatgt cgagcaggtt aaggaaaaac tcttactttt
     1141 gccctatatt agggaagaat tagcatcttt aaatcagtga ggtatcctat gaaaatagca
     1201 gtagcaggga caggttatgt gggtttatct attgcaattc tattagcgca atatcataag
     1261 gttatagcgg tagatgttat tcctgaaaaa gtagagctta tcaatcgtcg ccaatctccc
     1321 attaaggatg atgatattga aacttattta gtggaaaagg aattagactt agttgcaaca
     1381 ttagatggta atgaagctta tcgagatgct gactttgtca taattgctgt cccaactaac
     1441 tatgacagta aaaaaaatta ttttgataca tctgttgtgg aagcagttat tgagcagatt
     1501 attgcggtta atttgaaggc aacaattgtc ataaaatcca caattcctgt gggatataca
     1561 gaaagtctcc gaacacgttt tgggcaattt aagattctct ttagtcctga atttttacgg
     1621 gagtctaaag cactttatga taatctctat cctagtcgaa tcatcgttgg agcagatttg
     1681 agagatacgg agcaggtagt tcaggctgag cggtttgcaa ctcttttgca ggaaggttca
     1741 cttaaacctg atgttgagac cttaattatg ggtgtaacag aggcagaagc agtcaaacta
     1801 tttgccaaca cctatttggc tttgcgggtt tcttacttta acgaattgga tacctatgcg
     1861 gagataaagg gattggacac taaatccatc attgacggag tagggttaga tccacgaatt
     1921 ggtagccatt ataacaatcc gtcatttggt tatggaggtt attgtcttcc caaagatagt
     1981 aagcagttgc tggcgaatta tcatgatgta ccacaaaata tgatgacagc tattgtagaa
     2041 agtaaccgta ctcgcaagta ttttattgcc gatcgtattt tgaaaaatgc gttggagctt
     2101 tcagacggta atcaaacaat catagtaggt gtttaccgct taactatgaa gagtggttcg
     2161 gataatttcc gtcaatcatc aatccaaggt gttataaaat gtttaaaggc caaaggtgta
     2221 gaagtaatta tctatgaacc aactttggag gatcatagct ttttctttgg taatcaggtg
     2281 gttaatgatt tggaagtttt taagtctagc agtcaagtga ttgttgccaa tcggatggaa
     2341 aaatctttat atgatgtgct agaaaaagtt tatacaagag atatttttca gcgagattaa
     2401 gtatatggag ggaaaaatat gccattaaaa attttagtga ctggttctaa aggatttgta
     2461 ggaaaaaatc ttatctgtac tctggaagct ttgaaagatg gacgagatag gactcgtcct
     2521 aatttagaga ttggagagat ttttcagtat gatcgtgata cagatccgat tttattagat
     2581 gaatattgta agaaggccga tttcgtattc catttagctg gtgtcaatcg tccacagaat
     2641 cctgatgaat tcatggaggg aaattacggt ttttcaagta gattattgga gattttagaa
     2701 aagtatgaaa acacttgtcc tgttctactc tcaagttcta ctcaagctag tttagaaggc
     2761 cgattttcaa actctatata tggacaatct aagctagtag gggaagaact cttctttgaa
     2821 tatggaaaga aaacgggagc acctgtctta gtttaccgtt tcccgaatct ttatgggaag
     2881 tggtgccgtc ctaactacaa ttctgctgta gcaactttct gtcataatct agctcacgat
     2941 ttacctattc aagtaaatga tccaagtgta gaattggagt tgctgtatat tgatgatttg
     3001 atacaagagt gtctaactgc attggaagga aatcctcatc gttgtaatct agatggatta
     3061 caaatcttac ctagcccatc aggaaactac tgctacgtac caacgactca tcgtgcaacc
     3121 ttaggagaga ttgtctctct attagaaaca tttaaaaaac agcctaatag tttagttatg
     3181 cctgaaattc ctcaaggatc gtttaaaaag aaattgtatt ctacctacct atcttattta
     3241 ccagtagata agtttaagtt tcctctaaaa atgaatatag atgaacgagg tagttttacg
     3301 gaattattaa aaacagaaaa taagggtcaa ttttctgtta atatttctaa acctggcatt
     3361 accaaagggc aacattggca tcattctaag tgggaatttt tcatggttgt ttctggtcgt
     3421 gctttaatac aagagcgtag gatagggctg gatgaaaacg gtcaagagta tcctattctg
     3481 aactttgaag tgtcgggcga taagattgaa gcaatacata tgataccggg ctatgcacat
     3541 aatattatta atctttctga tacagaaaat ctagttactg tcatgtgggc taatgagtca
     3601 tttgatccta gacatccaga tacttttttt gaacaagtgg agaaataaat gaaaattaag
     3661 acagattata gtgatattca ctttaaagat aatggcaaac ttaagttatt gattattgtg
     3721 ggaacacgtc cagagattat acgtctaagt agtgttatca ctaaatgtcg aaagtatttt
     3781 gatgttattt tggcacatac tggacaaaac tatgattaca atttaaatgg tattttcttt
     3841 gataatttag ggttagacac tccggacgta tacatggatg ctgttggaga tgatcttggt
     3901 gctactgtag ggaatattat taatacttca tacaaattga tgaatcaaat taaaccagat
     3961 gctttattga ttttagggga tacaaattct tgtttatcag ctattgctgc caagcgttta
     4021 catattccaa tttttcatat ggaggctggc aatcgctgta aggatgagtg cctgccggaa
     4081 gagactaatc gtcggattgt cgatattatt tcagatgtta acttagcata ctctgaacat
     4141 gcacgtaagt atttacatga gtgtggttta cctaaagagc gcacatatgt aacaggttct
     4201 cctatggcag aagtgttaca taaaaattta tctgccattg agtcttcaga tatccatgaa
     4261 cgtttgggat tgaaaaaagg aggttatatc ttactttcag ctcaccgtga ggaaaatatt
     4321 gatacagata aaaattttat ttctctcttt acagcaatta atcaattagc tgaaaagtat
     4381 aatatgccaa tcttatattc ttgccatcct agatcaaaga aaaggctaca agagagcggt
     4441 tttaaactag ataaacgtgt gattcagcat gagccactag gattccatga ctataattgt
     4501 ttacagatga atgcatttgt tgtagtatct gattcgggaa ctttaccgga agaaagtagt
     4561 ttctttacta gtcaaggtta tccttttcct gctgtatgta ttcgtacaag tacagaacgt
     4621 cctgagtcct tagataaggc aggatttatt ttggcaggca ttgatgaaaa ttctcttctt
     4681 caagcagttg aaactgctgt tagcttggca gaagatgagg attttggatt accggttcca
     4741 gattatgttg aggaaaatgt ctctactaaa gttgttaaga taatacagag ctatacaggg
     4801 atagtggata aaatagtttg gaggaaaagc tgaattgtat atttttaata aatcaaaacg
     4861 agatgattaa ttcttagtag aacaagagta aaattgaacg tatttgatgg aaatgtctta
     4921 cttgatagtc gagggatagc cattctatcg gatttttggc ttgtttttgc gcttcatgtt
     4981 tgatagaata aagggctctt tgtcaactgt agtgggttga agaaaagcta agcttgagaa
     5041 aggacaaatt tcgtcctttc ttttttgatg ttcagagcga tgaaaatccg ttttttgaag
     5101 ttttcaaagt tccgaaaacc aaaggcattg cgcttgataa gtgtaagcgc gtcataacaa
     5161 ggtatctatc attcatggag ctcctcctgt atactattag taaagtaaaa ctattggagg
     5221 atattttaat gccacaacct attgttcctg tagagattcc acaatctcgt cgttttgatt
     5281 ctaaaaagag aaatgatatt ctgcttaaaa ttcgtattgg caagcttgaa gtaagttttt
     5341 ttcaatctct caatctcgaa atgatagaac agcttttgga taaggtgttg ctctatgaca
     5401 attcatctat ctagcctagg gcaggtctat ctcgtatgtg ggaaaacgga tatgaggcaa
     5461 ggcattgatt cactggctta tctggttaaa acccactttg aattagatcc tttctcaggt
     5521 caagtttttc tcttttgtgg tggacgtaaa gaccgcttta aagcccttta ctgggatggt
     5581 caaggatttt ggctactata taaacgcttt gagaacggca gactgacttg gcccagtaca
     5641 gaaaaggatg tcaaagctct cacacctgaa caagtagact ggcttatgaa gagcttttct
     5701 atcactccca aaataaactc atcagaaagt cgtgatttct attgaaatga ggactttctt
     5761 tttagtataa taaagttaga aaacagagag ggaagctcat ggaagaagat tgaaaatcat
     5821 tcaacaacag agtgctacaa ttgatagtct caccaatgaa cttgcccttc ttcgtgaaca
     5881 agtggcttat ctgactcaaa agctctatgg aaaatcctct gagaaaagtg tttgcccctc
     5941 tggacaactc aacctttttg aggaagagtc tccatctgag gaagatggag atgttcccag
     6001 ttgaaacaga ggaaattacc tacaaacgta agaaatctaa agggaaacgc caagctcttc
     6061 ttgcccaatt tgattcagaa gaagttcatc atcaagtaga agagaggatt tgccctgatt
     6121 gtcagggaga tctaaaagag attggaggga gtcttcaagg acaagaattg gtctttattc
     6181 ctgcgcaatt aaaacgcata gatcatatcc aacacgctta caaatgccaa gcatgcagtg
     6241 ataaaaatcc gagtgataaa atcgtgaaag ctcctattcc taaagcccct ttataacgag
     6301 actattgact caagccctta cttcatgcgg atgaaacctc ttatcgggtt ctagagagtg
     6361 atagtcagtt gacttactat tggacttttt tgtctgggaa agctgagaat caagcaatca
     6421 cgctgtacca ccatgatcag cgtcggagtg gtttagtagt acaagaattc ctaggagatt
     6481 attctggcta tgttcattgt gacatgttgc ggcagtaact taggacttta gtcctctagt
     6541 tctgcctatg cgatagcagt ccaaagttta ggagtaaggc gacgctaagc ttggtaaact
     6601 gcgaacagct agaagcttat cgtcaactgg aagaagctgc acttgttgga tgttgggcgc
     6661 atgtgagaag gaagtttttt gaagtgcccc ccaagcaagc agataaatca tccttaggag
     6721 ctaaaggttt agcttattgt gatcagttat tttccttgga aagagactgg gaggctttgc
     6781 cagctgatga acgactacag aaacgtcaag aacatctcca acccctactg gaagacttct
     6841 ttgcttggtg ccgtcgtcag tcagttttat cgggttcaaa actaggaagg gcaattgaat
     6901 acagcctcaa gtatgaagaa acctttaaga ccattttaaa agacgg
//
LOCUS       DAVHSI010000069         6526 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.070, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000069 DAVHSI010000000
VERSION     DAVHSI010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.070"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            106..1272
                     /locus_tag="VVR21_002007"
     CDS             106..1272
                     /locus_tag="VVR21_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU6055796.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYNLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMCNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            1411..1737
                     /locus_tag="VVR21_002008"
     CDS             1411..1737
                     /locus_tag="VVR21_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU6055797.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            1724..2317
                     /locus_tag="VVR21_002009"
     CDS             1724..2317
                     /locus_tag="VVR21_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU6055798.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            2310..3221
                     /locus_tag="VVR21_002010"
     CDS             2310..3221
                     /locus_tag="VVR21_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU6055799.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENANLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            3284..4348
                     /locus_tag="VVR21_002011"
     CDS             3284..4348
                     /locus_tag="VVR21_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055800.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAKEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISTLVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(4526..5386)
                     /locus_tag="VVR21_002012"
     CDS             complement(4526..5386)
                     /locus_tag="VVR21_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU6055801.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWLIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(5508..6494)
                     /locus_tag="VVR21_002013"
     CDS             complement(5508..6494)
                     /locus_tag="VVR21_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU6055802.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
BASE COUNT         1867 a         1522 c         1192 g         1945 t
ORIGIN      
        1 caagactttc ccatttttat cttgaaagcc agaaacctta cttgacatta tagtgaaaaa
       61 gccttaaaat aagctgttat taaaatcagc tagaagaggt attatatgaa aaagcaatca
      121 ctcttttttg ttccaggtat tatcctgatt ggtgtttcct tgcgaactcc ttttactgtt
      181 ttacccatta ttttgggaaa tatttcgcaa ggtctggagg tagaagttag ttcgcttggt
      241 gtcttgacca gcctgcctct ccttatgttt accctctttt caccattttc tacccgactg
      301 gctcagaaaa ttggcttgga gcatctcttc acctacaacc tcttcttctt gaccatcggc
      361 tcacttattc gactaatcaa tctgcccctg ctctatctag gaaccttgat ggttggggca
      421 agtgtcgcag tcatcaatgt cctgcttcct agtcttatcc aagccaatca accaaagaaa
      481 attggttttc tgaccacctt atatgtaacg tctatgggga ttgcaacggc tctggcttcc
      541 tatctagctg tgcccattac acaagccagt tcttggaaag gacttatcct cctcctcacg
      601 ttactctgtc tagcaacttt tttggtctgg ctcccaaatc accgctataa tcatagacta
      661 gctccacaaa ccaaacaaaa aagtcaaata aaggtcatgt gtaataaaca ggtttgggca
      721 attattatct tttcaggttt tcaatccttg atcttttaca ccgtcatgac ctggttacct
      781 accatgtcta tccatgcagg tctatccagt cacgaagctg gcttgctgac ttctatctta
      841 tctctgatta gcattccttt ttcaatgacc atcccaagcc tgacaaccag tttatctact
      901 cgcaaccgtc agctcatgct cactctggtt tcactagctg gtgtggtcgg catttccatg
      961 ctctttttcc caatcaataa tttcatttac tggcttgcca tccatctcct catcggaacc
     1021 gcaaccagcg ccctcttccc ttatctcatg gtcaactttt cactcaagac aagcgcccct
     1081 gaaaagacag cccaattgtc cggtctatct caaacaggag gctatatcct agcagccttt
     1141 gggccaaccc tctttggtta cagttttgac ctgttccact cttgggtacc agctgtagct
     1201 gccctcttgc tcatcgatat cctgatgact gtggccctct ttacagtgga cagagcggat
     1261 aagatccttt aaacttctag ttttagctag aagtttttta tatataaaaa ttttacacat
     1321 ttctcttgac agggctttct tttagatgta caatatatgt gtagaaaaat tatatataaa
     1381 aatcttacac attagaaaag gaggtttccc atgtactttc caacatcctc tgccttgatt
     1441 gaatttctca tcttggccgt actggagcag ggtgattctt atggttatga gattagccaa
     1501 accattaagc tgatcgctaa tatcaaagaa tccacactct atcccattct caaaaaattg
     1561 gaaggcaata gctttctgac aacctattct agagagttcc aaggtcgcat gcgcaaatac
     1621 tactccttga caaacggtgg tatagagcag ctcttgaccc taaaagatga atgggcactc
     1681 tatacagaca ccatcaatgg catcatagaa gggagtatcc gccatgacaa gaactgaata
     1741 cctgactcag ctagaactct atctcaagaa actacctgaa gctgaccgta tcgaagccat
     1801 ggactatttc agagagctct ttgacgatgc tggagtcgaa ggagaagaag aactcatcgc
     1861 tagtttggga actcccaaag aagcggccca cgaagttcta tccaatcttc tcgataaaaa
     1921 aatcaatgaa gcacccgctc aaaaaaataa ccgacaaatt ttacatatcg ccttgttagc
     1981 cctccttgca gcacctatcg gcattcctct gggaatcgcc atcctcgtga ccctgttcgc
     2041 aatccttgta gccgctttga ctgtcattct ggctttcttt gcagtttcca tactgggtat
     2101 catcggcgga ttcctatttt tagttgaaag tttcactgtc ctcgcccaag ccaaatcagc
     2161 ctttatcttg atttttggtt ctggtttact ggctatcggt gcttcttcgc tagttttact
     2221 aggcatttcc tatgtagctc gcttcttcgg tctactcatt gttcgcctgg tacaatttgt
     2281 tcttaaaaaa agaaagagag gtaaccagca tgcgtaaatg gacaaaagga tttctcatct
     2341 ttggtgtggt gactaccgtt atcggcttta tcctgctttt tgtaggtatc caatctgacg
     2401 ggattaagag cctactttcc atgtccaaag aacctgtcta tgatagccgt acggaaaagc
     2461 taacctttgg caaggaagtc gaaaacctag aaattactct ccaccaacac acgctcacca
     2521 tcacagactc tttcgatgat caaatccaca tttcttacca tccatctctt tctgctcacc
     2581 atgatcttat caccaatcag aacgatagaa ctctgagtct cactgataag aaactgtctg
     2641 aaactccgtt tctctcttct ggaattggtg ggattcttca tatcgcaagt agctactcta
     2701 gtcgttttga agaagttatt ctccgactac caaaagggag aactctaaaa gggatcaaca
     2761 tctcagccaa tcgcggacaa accaccatca taaatgctag ccttgaaaat gcgaacctca
     2821 atacaaacag ctatatcctc cgaattgaag gaagtcgtat caaaaacagt aaactcacaa
     2881 cgcccaatat cgttaatatc tttgatacag ttcttacaga tagtcagcta gagtcaacag
     2941 ataatcactt ccacgctgaa aatatccaag tccatggtaa ggttgaactg actgccaaag
     3001 attatctcag aatcatccta gaccagaaag aaagccaacg aattaactgg gacatctcaa
     3061 gcaactatgg ttctatcttc caattcacaa gagaaaagcc tgaatcaaga ggtacggaat
     3121 taagcaaccc ttacaaaact gaaaaaaccg atgtcaagga tcaactcatt gcgagatctg
     3181 atgataatat tgatctaata tccacaccaa gcagacgttg acaaaaacgc ttacatctgc
     3241 tactatggaa gcatatttat ctaactaaaa aggaggttct accatgaaac aagaatggtt
     3301 tgaaagtaat gattttgtaa aaacaacaag caagaacaag cctgaagagc aagctaaaga
     3361 ggttgcagac aaggctgaag aaacgatagc cgatctcgat acaccaattg gaaaaaatac
     3421 tcaagtagag gaggaagtct ctcaagctga agtcgaattg gaaagccagc aagaagagaa
     3481 aattgaaact cctgaagtcg gtgaagcgag aacagaaata gaagaaaaga aggcatctaa
     3541 ttctactgaa gaagagccag acctttctaa agaaacagaa aaagtcacta tagctgaaga
     3601 gagccaagaa gctcttcctc agcaaaaagc aaccacgaaa gagccacttc ttatcagtaa
     3661 atctttagaa agtccttata tccccgacca agctccaaaa tctagggata aatggaaaga
     3721 gcaagtgctt gatttttggt cttggctagt ggaagcgatc aaatctccta caagtaagtt
     3781 ggaaacaagt atcacacaca gttacacagc ctttctcttg ctcattctgt tttctgcatc
     3841 ttcctttttc tttagtatct atcacatcaa acatgcttac tatggacata tagcaagcat
     3901 taacagtcgc ttccctgagc agctagctcc tttaactctt ttttctatca tctctaccct
     3961 agtagcgaca acactcttct tcttttcatt cctcttgggt agtttcgttg tgagacgatt
     4021 tatccaccag gaaaaggact ggacgctaga caaggttctc caacaatata gtcaactctt
     4081 ggcaattcca atcttcctca ctgctattgc tagtttcttt gctttctttg atagcctacg
     4141 atttacagct ctcttgtgtg tgattagcat tggaatcatt ctgcttgcca gtctccatat
     4201 cattacaaga ccaagtcaag caagtgaaac cgactccttc tatcaattat tcttgtctgt
     4261 ccttgtgaac ggagttatta tcctcctctt ctttgtagct gaagtggcac tgattggaga
     4321 ttatcttcgt atcttggcct ttctttaaac ttcatactct tcgaaaatca aattcaaacc
     4381 acgtcagctt cgccttaccg tactcaagta cagcctgcgg ctagcttcct agtttgctct
     4441 ttgattttca ttgagtagca atcctgtcat tcttggcagg attttttcta tgtcaaaaaa
     4501 gcaagtcgat tgacctgctt ctgctttact tttcttgtgc taatgtttta aaatcttgtc
     4561 ctaggatggg ttgtatttct atttgattgg cgtctagttg gtggtaaaaa gatgggggta
     4621 atacctctaa gaattttgca tagtccaagc gagctatgga ttcatagtct tctggtttag
     4681 agccgtctcc tgtgatttga accaagtcaa tctcccactg gacttcctta tccaccaatt
     4741 gctcaatata ggctgcagga acaaacggtt ctctcggtaa aactgtcttg actccttgag
     4801 ctagatggta aacgccatgc acttttcctt ctccatcctg atagaaggaa actctcgcaa
     4861 agtaggcatc tgtctcttga accgcacgca cacgcgcttc aaactgagcc aagccatctg
     4921 cctctaaaaa gcttttcaag ttctcacgac taaagaaaat aggattaaaa attccttggc
     4981 aaatcgtaaa acgagctaca gggtctgcta gataggcttg aatacttgct tggaaataag
     5041 cttcaaaatc aaaaccatct agcccttcaa tatcagtccc tgtataagca agcaaagcat
     5101 ctaaaaatga cttgataatc agccagtctg tctttgttag taggtcagga agatcgacac
     5161 ggtaagcctt ttgaccatca gcataactga ccttaaaaag aaattgtgat tgccccacta
     5221 tcgcacactc aatatattcg agacgattaa gaggctgacg gagatagact acatcatagc
     5281 tatgtgactc caaaccgtct agcaaggcca agatcgattt ggcattcaaa atctcttgtt
     5341 ctcctaaaat gctctgttta tttggaataa aaaatgtttt cgccataact ggactccttt
     5401 gaaatcgctt acatacagta taccttattt ttctgaaaga tacagaaaca aactttagat
     5461 ttttgagtac aaagcataga aaaacagccc ctgaggactg tttgatctta tacagtagct
     5521 gcttgatcca agctttcacc gatagcggct aggcgctcga tcacttcagc ttgtgtcaat
     5581 tcattttttg aaacatagcg gttacgtggg tgaacacggc actcgtgtga gcatccacga
     5641 aggtacttgt cttcattttc ttctgatgtc aagatacgac ggttacagaa gggatttcca
     5701 cagttgacat aacgttcaca tggcgttcca tcaaaccagt ctttccctac gatagttggg
     5761 ttgacatggt tgacatcaac ggcaatacgc tcgtcaaaga cgtacatttt cccatcccaa
     5821 agctcacctt gaacttctgg gtctttaccg taagttgcga ttcctccgtg caattggcca
     5881 acatctttgt aaccttcacg aaccatccag cctgagaatt tctcacagcg aacaccacct
     5941 gtacagtaaa ccacgacacg cttgtccatg aatttttctt tgttgtcacg gacccattgt
     6001 ggtaactcac ggaagttgcg aatatctggg cgaatagccc cacggaaatg tcctaggtcg
     6061 tactcataat cgttacgtgt gtcaaggaca acggtatctt tatcaagaag cgcttctttg
     6121 aactcttttg gagacaagta agcacctgtt gtttcaagtg ggttgatgtc attgtcaaag
     6181 tcgttgtctt ccaaaccaag gtggacaatt tctttcttgt agcgaacaaa catcttcttg
     6241 aaggcttgtt cattttcttc gtcaatcttg aaccagagat cttccattcc tggaaggctg
     6301 tgaacgtagt ccatgtattt ttgagttgtt tcatagtcac ctgaaactgt tccgttaatt
     6361 ccctcgtcag cgactaggat acggccttta aggccgattg atttacagaa agccaagtgg
     6421 tctgcagcaa attgctctgc attttcaatt ggagtataaa ggtagtaaag taagacacga
     6481 atatcttttg ccataagatt tgttctcttt tctattctta aatttt
//
LOCUS       DAVHSI010000070         6337 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.071, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000070 DAVHSI010000000
VERSION     DAVHSI010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6337
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.071"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            1..306
                     /locus_tag="VVR21_002014"
                     /pseudo
     CDS             1..306
                     /locus_tag="VVR21_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            473..673
                     /locus_tag="VVR21_002015"
     CDS             473..673
                     /locus_tag="VVR21_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055803.1"
                     /translation="MVVSASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            698..1114
                     /locus_tag="VVR21_002016"
     CDS             698..1114
                     /locus_tag="VVR21_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055804.1"
                     /translation="MKTALDSLKDVIANASDSKPTQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1345..2052
                     /gene="ccdA2"
                     /locus_tag="VVR21_002017"
     CDS             1345..2052
                     /gene="ccdA2"
                     /locus_tag="VVR21_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU6055805.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2063..2620
                     /gene="sdbB"
                     /locus_tag="VVR21_002018"
     CDS             2063..2620
                     /gene="sdbB"
                     /locus_tag="VVR21_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU6055806.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2994..4385
                     /locus_tag="VVR21_002019"
     CDS             2994..4385
                     /locus_tag="VVR21_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU6055807.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNVNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4528..5445
                     /gene="adcAII"
                     /locus_tag="VVR21_002020"
     CDS             4528..5445
                     /gene="adcAII"
                     /locus_tag="VVR21_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU6055808.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5453..>6337
                     /gene="phtD"
                     /locus_tag="VVR21_002021"
     CDS             5453..>6337
                     /gene="phtD"
                     /locus_tag="VVR21_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU6055809.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGL"
BASE COUNT         1944 a         1128 c         1345 g         1920 t
ORIGIN      
        1 ccagaaaaag tagccttatt tcttaagaat tttaatagtt taaagcacct agcacctgtt
       61 tagattgatg aaacaggatt tgatacttat ttttatcgag aatatggtcg ctcattaaaa
      121 ggtcagttaa gaagaggcaa agtatctgga agaagatatc agaggatttc tttggttgca
      181 ggtctaacaa atggtgaatt aatcgctcca atgacttacg aagagacgat gacgagcgac
      241 ttttttgaag tatggtttca gaaatttctc ttaccaacat taaccacacc atcggttatt
      301 atagtaaaat ggaataagaa caggacaaat cgatcaggac aatcaaatca atttctagca
      361 atgttttaga agtccatatg tactattcta gtttcaatat accataactg ctcctagtca
      421 acctgcaagt cctgtcccag ctccaagctc agctccgact caagatccta gagtggtagt
      481 aagcgcttcg gctagctcaa cgagcacaca agctcaagag caagttgaca agtctgaact
      541 tcgtgccttg agtcaagagt tagaccaacg cttgaaagct ttggcaacag tatctgatcc
      601 gaaaatcgat gcaaccaagg ctgtcctcct agatgctcaa aaagctccgg aagatagtgc
      661 cttgacagag taaggtctgc atactgcagt agagtctgtg aagactgcct tggactctct
      721 caaagatgtg atagcaaatg ctagcgacag caagcctaca caggacaaga aggatgcaaa
      781 acaaggaacg gaagatagta aggattcaga taagatgact gaaacaaact cagttccagc
      841 aggagtgatt gtggtcagtc tacttgccct cctaggcgtg attgccttct ggctgattcg
      901 ccgtaagaaa gagtcagaaa tccagcaatt aagcacggaa ttaatcaagg ttctaggaca
      961 gctagatgca gaaaaagcgg ataaaaaagt ccttgccaaa gcccaaaacc ttctccaaga
     1021 aacccttgat ttcgtgaaag aagaaaatgg ctcagcagag acagaaacta aactagtaga
     1081 ggagcttaaa gcaatccttg acaaactcaa gtaaaacatg atttatgaaa tgtcagactt
     1141 aaaagacatt ttcgttcaca aaagcagcga cgagtaatcc ttgtcgttgc tttttggcta
     1201 ttttggggga taagatccgc cttgactagc aaaagaaaag attggtccaa tagtgcccga
     1261 tacgattttg cgtagcagaa agcttacaaa taaaattgaa tatagtaaaa taggattaga
     1321 attattaaga aagttggttc tttattggaa acgatagtat ttttaatctc tgtttttcta
     1381 gcaggtgttt tatccttttt ttctccttgt atttttcctc ttctgccagt ctatgctggg
     1441 attttattgg atgatcaaga aagtgcaaaa agcttttctt tgtttgggag aaaggttctc
     1501 tggtcaggct tgattcgaac actttgcttt atcgctggta tctctctcat tttctttatt
     1561 ctaggctttg gtgctggtta ctttggtcat attctctatg caaattggtt tcgatatggc
     1621 atgggagcta ttattatcat tttgggtctt caccagatgg aaatttttca tttgaagaaa
     1681 ttagaagttc aaaaaagttt tacctttaaa aaatcagatt ctaatcgtta ttggtcagct
     1741 tttttacttg gtattacctt tagctttggt tggacacctt gtattggtcc agttttaagt
     1801 tctgttttag cacttgcggc ttctggaggc aatggcgctt ggcaaggagc gatttatact
     1861 ctcatttaca ctctgggcat ggcccttcct ttcttggtat tggcactagc ttcaggtcta
     1921 gtcatgccat attttagtaa aatcaagcgt catatgatgc tactaaagaa aattggtggt
     1981 ttcctcattg ttttaatggg aattttgtta ctattaggac aagtaaatgt tctagctgga
     2041 atttttgaat aaaggaggac aaatgaaaaa agtaatgttt gctggcttaa gtctcttgtc
     2101 attagttgta ttgatggcct gtggtgagga agaaactaaa aagactcaag cagcacaaca
     2161 gccaaaacaa caaacgactg tacaacaaat tgctgttgga aaagatgctc cagactttac
     2221 attgcaatcc atggatggca aagaagttaa gttatctgat tttaagggta aaaaggttta
     2281 cttgaagttt tgggcttcat ggtgtggtcc atgcaagaaa agtatgccag agttgatgga
     2341 actagcggcg aaaccagatc gtgatttcga aattcttact gtcattgcac caggaattca
     2401 aggtgaaaaa actgttgagc aattcccaca atggttccag gaacaaggat ataaggatat
     2461 cccagttctt tatgatacca aagcaaccac cttccaagct tatcaaattc gaagcattcc
     2521 tacagaatat ttaattgata gccaaggaaa gattggaaag attcaatttg gtgctatcag
     2581 taatgcggat gcagaagcag catttaaaga aatgaactag aatcgataaa atctgattac
     2641 aagatgtagt cagattttgg taacttctaa aactaacttc cagtttccca caacctagct
     2701 tttagtatga gaaaaacgcg tgacatcagt ggaaatccgt cttagattaa cttccactgg
     2761 ttttcttttt cttgatatat aagggttcaa aagcgaaaag actcagaaaa agtgcacgac
     2821 aaatagccct aaaacagagt cgtctgagac taacttccag ttttgggaga gagatggaag
     2881 ttactttgag aagttacggt agtcagattt ttttagaaaa atattttata aatattcaca
     2941 tatctcctat atttatggta aaatagaatc atcagtttat tttggagtca aagatgaata
     3001 tatttagaac aaagaatgtt agtttagata aaacagagat gcataggcat ttgaagttat
     3061 gggatttgat tttgctgggt attggagcca tggtagggac aggtgttttt acaatcacag
     3121 gtactgcagc tgctacactt gctggtccag cactagtgat ttcaatcgtt atttctgcct
     3181 tgtgtgtggg attatcagcc ctcttttttg cagaatttgc ctcgcgagta cccgctacag
     3241 gaggtgccta tagttacctc tatgctatct taggagaatt ccctgcctgg ttggctggtt
     3301 ggttaaccat gatggagttc atgacagcca tatcaggcgt agcttcgggt tgggcagctt
     3361 attttaaagg cttgctctct caatacggga tagcccttcc tcaggcttta aatggtacct
     3421 ttaatcctca agcagggaca tttgttgatt tattgcctat tcttgtcttg gtcttggtga
     3481 cttcgcttgt tttactaaat gccaaggcag ccttacgctt taattcgatt ctagttattt
     3541 tgaaattttc cgctttagct ctctttgttt tagtaggaat ttggaatatt aagtttgata
     3601 attggagcaa ttttgctcct tacggttttg gacaaatcta tggagctagt actggtatta
     3661 tggctggtgc gtccttgatg ttcttcggtt ttttgggatt tgaatccatc tctatggctg
     3721 tagatgaagt caagactcct caaaaaaata ttcctagagg gattgtctta tcgctttcta
     3781 tcgtaaccat tctctatgcc ttggtgaccc ttgttttgac tggtgtggtt cactatagtc
     3841 atttaaatgt cgatgatgcc gttgcctttg cccttcgtag tgttgggatt agttgggcag
     3901 ccaactatgt gtcattagtg gctatcttga ccttgattac agtttgtatt tcgatgacct
     3961 atgccctatc gcgtatgatt tacagtttag cacgtgacgg cttagtgcct gctgccttta
     4021 aggaactgac gaagactagc aaggtaccaa agaatgctac tatcttgaca ggtctagctt
     4081 cagcagtagc agcaggaatg ttcccactag ccagtattgc agccttttta aatatttgta
     4141 ccttagccta cttgatcctg ctggcttatg gtctgattcg cttacggaaa gaaaaaggaa
     4201 tgcccaaagc tggggaattt aaaacaccat tggtacctct gttaccaatt ttatcgatca
     4261 tcatttgttt atccttcatg ttacagtata atgtgaacac ctggattgct ttcctagttg
     4321 cgttgttagt aggaagtatt atttacttca cttatggcta taagcattct accatagaag
     4381 aataaagtga aagtctattg agttgttgac actcagcaga tttttatatg tgaaagaaat
     4441 ttcaaatttt ttctaaaaat atcttgacag attaaatttt caggagtaga atatttacta
     4501 gttaattaaa tggttaagga gttgttcatg aagaaacaaa atttattttt agtcctgtta
     4561 agtgtctttc ttttatgctt gggggcttgt ggtcaaaagg aaagtcagac aggaaagggg
     4621 atgaaaattg tgaccagttt ttatcctatc tatgctatgg ttaaggaagt atctggtgac
     4681 ttgaatgatg ttcggatgat tcagtcaagt agtgggattc actcttttga accttcggca
     4741 aatgacatcg cggccatcta tgatgcagat gtctttgttt accattctca tacgctagaa
     4801 tcttgggcag gaagtttaga tcccaatcta aaaaaatcca aagtgaaggt cttagaggct
     4861 tctgagggaa tgaccttgga acgtgtccct ggactagagg atgtggaagc aggggatgga
     4921 gttgatgaaa aaacgctcta tgaccctcac acatggctag atcctgaaaa agctggagaa
     4981 gaagcccaaa ttatcgctga taaactttca gaggtggata gtgagcataa agagacttat
     5041 caaaaaaatg cgcaagcctt tatcaaaaaa gctcaggaat tgactaagaa attccaacca
     5101 aaatttgaaa aagcgactca gaaaacattt gtaacacaac atacagcctt ttcttatcta
     5161 gcgaagagat ttgggcttaa tcaacttggt attgcaggca tctctcctga acaagaacca
     5221 agtccacgac aattaacaga aattcaggaa tttgttaaaa cctataaggt taaaacgatt
     5281 tttacagaaa gtaatgcttc ttcaaaagta gctgaaactc ttgtcaaatc aacaggtgtg
     5341 ggtcttaaaa ctctgaatcc tttagaggca gacccacaaa atgacaagac ctatttagaa
     5401 aatctggaag aaaatatgag tgttctagca gaagaattaa agtgaggaaa gaatgaaaat
     5461 caataaaaaa tatctagcag gttcagtggc agtccttgcc ctaagtgttt gttcctatga
     5521 acttggtcgt caccaagctg gtcaggttaa gaaagagtct aatcgagttt cttatataga
     5581 tggtgatcag gctggtcaaa aggcagaaaa tttgacacca gatgaagtca gtaagagaga
     5641 ggggatcaac gccgaacaaa ttgttatcaa gattacggat caaggttatg tgacctctca
     5701 tggagaccat tatcattact ataatggcaa ggttccttat gatgccatca tcagtgaaga
     5761 acttctcatg aaagatccga attatcagtt gaaggattca gacattgtca atgaaatcaa
     5821 gggtggctat gtgattaagg tagacggaaa atactatgtt taccttaaag atgcggccca
     5881 tgcggacaat attcggacaa aagaagagat taaacgtcag aagcaggaac gcagtcataa
     5941 tcataactca agagcagata atgctgttgc tgcagccaga gcccaaggac gttatacaac
     6001 ggatgatggg tatatcttca atgcatctga tatcattgag gacacgggtg atgcttatat
     6061 cgttcctcac ggcgaccatt accattacat tcctaagaat gagttatcag ctagcgagtt
     6121 agctgctgca gaagcctatt ggaatgggaa gcagggatct cgtccttctt caagttctag
     6181 ttataatgca aatacagctc aaccaagatt gtcagagaac cacaatctga ctgtcactcc
     6241 aacttatcat caaaatcaag gggaaaacat ttcaagcctt ttacgtgaat tgtatgctaa
     6301 acccttatca gaacgccatg tggaatctga tggcctt
//
LOCUS       DAVHSI010000071         6011 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.074, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000071 DAVHSI010000000
VERSION     DAVHSI010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.074"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            284..1645
                     /gene="dnaA"
                     /locus_tag="VVR21_002022"
     CDS             284..1645
                     /gene="dnaA"
                     /locus_tag="VVR21_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU6055810.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            1804..2940
                     /gene="dnaN"
                     /locus_tag="VVR21_002023"
     CDS             1804..2940
                     /gene="dnaN"
                     /locus_tag="VVR21_002023"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU6055811.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            3005..3199
                     /locus_tag="VVR21_002024"
     CDS             3005..3199
                     /locus_tag="VVR21_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU6055812.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            3283..4398
                     /gene="ychF"
                     /locus_tag="VVR21_002025"
     CDS             3283..4398
                     /gene="ychF"
                     /locus_tag="VVR21_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU6055813.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELNDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            4469..5038
                     /locus_tag="VVR21_002026"
     CDS             4469..5038
                     /locus_tag="VVR21_002026"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU6055814.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            5039..>6011
                     /locus_tag="VVR21_002027"
     CDS             5039..>6011
                     /locus_tag="VVR21_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU6055815.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEE"
BASE COUNT         2068 a          964 c         1144 g         1835 t
ORIGIN      
        1 acagtggaaa aatcattatt tctttttcaa atcaagaaga atatagtaga attatcaaca
       61 gcctgaaata aggctgttct tttatttttt tatctcacaa ggttatccac tatgtttttc
      121 gataaaaagc ttaataaatc aataatttct tcttttatcc ccaacctgtg gataaagttt
      181 ggtaacattg tggattattt ttcacagctt gtggaaaatt cttgctatct atggtaaaat
      241 atctctagta ttaaactttt aaatagtaaa ggaggagaaa ggattgaaag aaaaacaatt
      301 ttggaatcgt atattagaat ttgcacaaga aagactgact cgatccatgt atgatttcta
      361 tgctattcaa gctgaactca tcaaggtaga ggaaaatgtt gccactatat ttctacctcg
      421 ctctgaaatg gaaatggtct gggaaaaaca actaaaagat attattgtag tagctggttt
      481 tgaaatttat gacgctgaaa taactcccca ctatattttc accaaacctc aagatacgac
      541 tagctcacaa gttgaagaag ctacaaattt aactctttat aactatagtc caaagttagt
      601 atctattcct tattcagata cgggattaaa agaaaagtat acctttgata actttattca
      661 aggggatgga aatgtttggg ctgtgtcagc cgctttagct gtctctgaag atttggctct
      721 gacctataac cctcttttta tctatggagg accaggcctt ggtaagactc acttattaaa
      781 cgctattgga aatgaaattc taaaaaatat tcctaatgcg cgtgttaaat atatccctgc
      841 cgaaagcttt attaatgact ttcttgatca cctaagactt ggggaaatgg aaaagtttaa
      901 aaagacctat cgtagtcttg atcttttgtt aatcgatgat atccagtcac tcagcggaaa
      961 aaaagtcgca actcaggaag aatttttcaa tacctttaac gcccttcatg acaagcaaaa
     1021 acagattgtc ctaacgagtg atcgtagtcc aaaacatcta gaagggctcg aggagaggct
     1081 tgtcacgcgt tttagttggg gattgacaca aactatcaca ccccctgact ttgaaacacg
     1141 tattgccatt ttacaaagta aaacggaaca tttaggctac aatttccaaa gtgatactct
     1201 agaataccta gctgggcaat ttgattcaaa tgttcgagat cttgagggag ccatcaacga
     1261 catcacttta attgccagag taaaaaaaat caaggatatc actattgata ttgctgcaga
     1321 agccattaga gcccgcaaac aagatgttag ccaaatgctc gtcatcccaa ttgataaaat
     1381 ccaaactgaa gttggtaact tttatggtgt tagtatcaaa gaaatgaagg gaagtagacg
     1441 ccttcaaaat attgttttgg cccgtcaagt agccatgtat ttatctagag aactaacaga
     1501 taatagtctt ccaaaaattg ggaaggaatt tgggggaaaa gatcatacca cagtcattca
     1561 tgcccatgcc aaaataaaat ctttgattga tcaagacgat aatttacgtt tagaaattga
     1621 atcaatcaaa aagaaaatca aataatttgt ggataacttt tagtttttta tcttttttat
     1681 ccacattttt taaacaagct aaaaaacttg atatgacttg tttaaaggct gttttccaca
     1741 gatttcacag actctattat tactattatc tttctaatac taaaaataaa taaaggagaa
     1801 tccatgattc atttttcaat taataaaaat ttatttctac aagcattaaa tactactaag
     1861 agagctatta gttctaaaaa tgccattcct attttatcaa cagtaaaaat tgacgtgacc
     1921 aatgaaggta ttactttaat tggttcaaat ggtcaaattt caattgaaaa ttttatttct
     1981 caaaaaaatg aagatgctgg tttgttaatt acttctttag gttcgatcct tcttgaagct
     2041 tctttcttta tcaatgtagt atctagttta cctgatgtaa ctcttgattt taaagaaatt
     2101 gaacaaaatc aaattgtttt aaccagtggc aaatcagaaa ttaccctaaa aggaaaagat
     2161 agcgaacaat atccacgaat ccaagaaatt tcagcaagca ctcctttaat acttgaaaca
     2221 aaattactca agaaaattat taatgaaaca gcctttgctg caagtacaca agagagtcgt
     2281 ccgattttaa caggtgtcca cttcgtattg agtcaacaca aagagttaaa aacagttgca
     2341 acagactctc atcgcctaag ccagaaaaaa ttgactcttg aaaaaaatag tgatgatttt
     2401 gatgtcgtaa ttcctagccg ttctctacgc gaattttcag cggtatttac agatgatatc
     2461 gaaactgtag agattttctt tgccaataac caaatcctct ttagaagcga aaatattagc
     2521 ttctatactc gtctcctaga aggaaactat cctgatacag atcgcttgat tccaacagac
     2581 tttaacacta ctattacttt taatgtggta aacttacgcc agtcaatgga gcgtgcccgt
     2641 cttttatcaa gtgcgactca aaatggtact gtgaaacttg aaattaagga tggggttgtt
     2701 agcgcccatg ttcactctcc agaagttggt aaagtaaacg aagaaatcga tactgatcag
     2761 gttactggtg aagatttgac cattagtttc aacccaactt acttgattga ttctcttaaa
     2821 gctttaaata gcgaaaaggt gaccattagc tttatctcag ctgttcgtcc atttactctt
     2881 gtgccagcag atactgacga agacttcatg cagctcatta caccagttcg tacaaattaa
     2941 gtgaaagagg ttgagcctgg ctcgcctctt ttatgatata atcgaaaaag aaaaggagag
     3001 tagtatgtat caagttggaa attttgttga gatgaaaaaa tcacacgctt gtacaatcaa
     3061 gtcgactggt aaaaaggcta atcgttggga aattacacgt gtaggagcag atatcaaaat
     3121 aaaatgcagt aattgtgagc atgttgtcat gatggggcga tatgattttg agcgaaaaat
     3181 gaataaaatt attgactgag aacccttagt tagagggtta gcactttatc cctttttgtg
     3241 ttataatatt agggattgaa atgaaaacgg agaatgagaa atatggcttt gacagcaggt
     3301 atcgttggtt tgccaaacgt tggtaaatca acactattta atgcaattac aaaagcagga
     3361 gcagaggcag caaactaccc atttgcgacg attgatccaa atgttggaat ggtggaagtt
     3421 ccagatgaac gcctacaaaa actaactgaa atgataactc ctaaaaaaac agttcccaca
     3481 acatttgaat ttacggatat tgcagggatt gtaaaaggag cttcaaaagg agaagggcta
     3541 gggaataaat tcttggccaa tattcgtgaa gtagatgcga ttgttcacgt agttcgtgct
     3601 tttgatgatg aaaatgtgat gcgcgagcaa ggacgtgaag acgcctttgt agatccactt
     3661 gcagatattg atacaattaa tctggaatta attcttgctg acttagaatc agtgaacaaa
     3721 cgatatgcgc gtgtagaaaa gatggcacgt acgcaaaaag ataaagaatc agtagcagaa
     3781 ttcaatgttc ttcaaaagat taaaccagtc ctagaagacg ggaaatcagc tcgtaccatt
     3841 gaatttacag atgaggaaca aaaggttgtc aaaggtcttt tccttttgac gactaaacca
     3901 gttctttatg tagctaatgt ggacgaggat gtggtttcag aacctgactc tatcgactat
     3961 gtcaaacaaa ttcgtgaatt tgcagcgaca gaaaatgctg aagtagtcgt tatttctgcg
     4021 cgtgctgagg aagaaatttc tgaattgaat gatgaagata aaaaagagtt tcttgaagcc
     4081 attggtttga cagaatcagg tgtagataag ttgacgcgtg cagcttacca cttgcttgga
     4141 ttgggaactt acttcacagc tggtgaaaaa gaagttcgcg cttggacttt caaacgtggt
     4201 atgaaggctc ctcaagcagc tggtattatc cactcagact ttgaaaaagg ctttattcgt
     4261 gcagtaacca tgtcatatga agatctagtg aaatacggat ctgaaaaggc cgtaaaagaa
     4321 gctggacgct tgcgtgaaga aggaaaagaa tatatcgttc aagatggcga tatcatggaa
     4381 ttccgcttta atgtctaaaa attaataaat ggtgtcaatt aggttggaaa aaaattccaa
     4441 cccttttggc ttttgaaagg aaaaataaat gaccaaatta cttgtaggct tgggaaatcc
     4501 aggggataaa tattttgaaa caaaacacaa tgttggtttt atgttgattg atcaactagc
     4561 gaagaaacag aatgtcactt ttacacacga taagatattt caagctgacc tagcatcctt
     4621 tttcctaaat ggagaaaaaa tttatctggt taaaccaacg acctttatga atgaaagtgg
     4681 aaaagcagtt catgctttat taacttacta tggtttggat attgacgatt tacttatcat
     4741 ttacgatgat cttgacatgg aagttgggaa aattcgttta agagcaaaag gctcagcagg
     4801 tggtcataat ggtatcaagt ctattattca acatatagga actcaggtct ttaaccgtgt
     4861 taagattgga attggaagac ctaaaaatgg tatgtcagtt gttcatcatg ttttgagtaa
     4921 gtttgacagg gatgattata tcggtatttt acagtctgtt gacaaagttg acgattctgt
     4981 aaactactat ttacaagaga aaaattttga gaaaacaatg cagaggtata acggataaat
     5041 ggtgacctta ttagatttat tctcagaaaa tgatcagatt aaaaaatggc atcaaaattt
     5101 aacagataag aaaagacaac taatacttgg tttatcaaca tctactaagg ctcttgcaat
     5161 tgcaagcagt ttagaaaaag aagataggat tgtgttattg acgtcaactt atggagaagc
     5221 agaaggactt gttagtgatc ttatttctat cttgggtgag gaactcgtct atccattttt
     5281 ggtagatgat gctcctatgg tggagttttt gatgtcttca caggaaaaaa ttatttcacg
     5341 ggttgaagcc ttgcgttttt tgactgattc atctaagaaa gggattttag tttgtaatat
     5401 cgcagcaagt cgattgattt taccgtctcc caatgcattc aaagatagta ttgtaaaaat
     5461 ctcagttggt gaagaatatg atcaacacgc gtttatccat cagttaaagg aaaatggcta
     5521 tcgaaaagtt actcaagtac aaactcaggg cgaatttagt cttcgaggag atattttaga
     5581 tatttttgaa atatcccagt tagaaccttg tcgaattgag ttttttggtg atgaaattga
     5641 tggtatcagg tcatttgaag tagaaacaca attatcgaaa gaaaataaga cagaactcac
     5701 tatctttcca gctagtgata tgcttttgag agaaaaggat tatcaacgag gacagtcagc
     5761 tttagaaaaa caaatttcaa aaactttatc acctattttg aaatcatacc tagaagaaat
     5821 tctttcaagt tttcaccaaa aacaaagtca tgcagactct cggaagtttt tatctttgtg
     5881 ctatgataag acatggactg tctttgatta tattgaaaaa gatactccaa tattctttga
     5941 tgattatcaa aaattgatga atcagtatga agtctttgaa agagaattag cgcagtactt
     6001 tacagaagaa t
//
LOCUS       DAVHSI010000072         5662 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.075, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000072 DAVHSI010000000
VERSION     DAVHSI010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.075"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            96..1271
                     /gene="mutY"
                     /locus_tag="VVR21_002028"
     CDS             96..1271
                     /gene="mutY"
                     /locus_tag="VVR21_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU6055816.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1326..2030
                     /locus_tag="VVR21_002029"
     CDS             1326..2030
                     /locus_tag="VVR21_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055817.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2023..3372
                     /gene="vicK"
                     /locus_tag="VVR21_002030"
     CDS             2023..3372
                     /gene="vicK"
                     /locus_tag="VVR21_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU6055818.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3374..4183
                     /locus_tag="VVR21_002031"
     CDS             3374..4183
                     /locus_tag="VVR21_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU6055819.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4274..4516
                     /locus_tag="VVR21_002032"
     CDS             4274..4516
                     /locus_tag="VVR21_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU6055820.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4518..4772
                     /locus_tag="VVR21_002033"
     CDS             4518..4772
                     /locus_tag="VVR21_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU6055821.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4819..5592
                     /locus_tag="VVR21_002034"
     CDS             4819..5592
                     /locus_tag="VVR21_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU6055822.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
BASE COUNT         1771 a          931 c         1265 g         1695 t
ORIGIN      
        1 gagtataagt agatagaaaa gttatatact atctattgaa aatattataa atcagataca
       61 aagacaggtg aaaccttctg tgttatacta gagatatgtt agatttgaaa gaatacggta
      121 tcgtcatgtg gccggaggag aaagtcattt ctttccgtga gaaacttctc gcttggtatg
      181 atgaaaacaa aagagatttg ccttggagga gaagtaaaaa tccttatcac atctgggtat
      241 ctgaaatcat gcttcagcag accagggtgg atacagttat cccttactac gaaagatttt
      301 tggactggtt tccaactgtc gaaagtctgg caactgcgcc tgaggagagt ttactgaaag
      361 cttgggaggg cttgggctat tattctcgag ttcgcaatat gcaggctgca gcccagcaga
      421 ttatgactga ctttggtggc caatttccaa atacctatga aggaatttcc agcttgaaag
      481 ggattggacc ttacacagca ggagccattt ccagtattgc ttttaacttg cctgagccag
      541 ctgtagatgg taatgtcatg cgggtcttgg cgcgtctgtt tgaagtcaac cacgatattg
      601 ggattccaag taatcgaaaa atttttcagg caatgatgga gatcttgatt aatccagatc
      661 gtccaggtga ttttaatcaa gccttgatgg acttagggtc tgatattgag tctcctgtaa
      721 atcccagacc tgaagaaagc ccagtcaagg actttagtgc ggcatatcag aatggaacca
      781 tggaccgtta tccaattaaa tctcctaaga aaaagccggt tcctatttat cttaaagcct
      841 tagttgtgaa aaattctcaa ggacaatttt tacttgaaaa aaatgaaagc gaaaagctct
      901 tggcaggttt ttggcatttc ccctttatag aagttgataa cttttcgcaa gaagagcagt
      961 ttgacctctt tcatcaggtt gcggaagaaa gtgtgaactt tggccccagt ccagaagaga
     1021 gtttccagca ggactatgac ctagatgttg attggcttga tgtttgtttt gatacagtcc
     1081 agcatgtttt tagtcatcga aaatggcatg tacagattgt agcaggtcag gtgagtgact
     1141 tccatgattt ttcagatagg gaagttcgtt ggctttcacc agaagaattc aagaattacc
     1201 cacttgccaa accccaacaa aaaatctggc aggcttatgc acaagccaac ttagacagta
     1261 gccaagacta gctattgtgt cttctgacta ttttttggta taatagtaga gaaaaaggtg
     1321 aacatatgaa aaaaatacta attgtagatg atgagaaacc aatctcggat attatcaagt
     1381 ttaatatgac caaggaaggt tacgaagttg taactgcttt taatggtcgt gaagcgctag
     1441 agcaatttga agcagagcaa ccagatatta ttattctgga tttgatgctt ccagaaattg
     1501 atggtttaga agttgctaag accattcgta agacaagcag tgtgcccatt cttatgcttt
     1561 cagccaaaga tagtgaattt gataaggtta tcggtttgga acttggggca gatgactatg
     1621 taacgaaacc cttctccaat cgtgagttgc aggcgcgtgt taaagctctt ctgcgtcgtt
     1681 ctcaacctat gccagtagat ggtcaggaag cagatagtaa acctcaacct atccaaattg
     1741 gggatttaga aattgttcca gacgcctacg tagctaaaaa atatggcgaa gaactagact
     1801 taacccatcg tgaatttgag cttttgtatc atttagcatc gcatacaggt caagtcatca
     1861 cgcgcgaaca cttgcttgag actgtctggg gttatgacta ttttggtgat gtccgcacag
     1921 ttgatgtgac tgtacgacgt ctgcgtgaga agattgaaga tacgcccagc cgaccagagt
     1981 atatcttgac gcgccgtggt gtagggtatt acatgagaaa taatgcttga tttactgaaa
     2041 caaaccattt ttaccagaga ttttatcttt atcctgattt tgttaggttt catccttgtt
     2101 gtgaccctct tattactgga aaatagacgt gataatattc agttgaagca aatcaatcaa
     2161 aaggttaaag atttgattgc aggagattat tccaaggttc ttgatatgca aggtgggtct
     2221 gaaatcacca atattaccaa taatttgaat gacttgtcgg aggttattcg tctcactcag
     2281 gaaaatctag aacaagagag taagaggcta aatagtattc tgttttatat gacagatggg
     2341 gttcttgcga ccaaccgtcg gggtcagatt atcatgatta acgatacagc caagaagcaa
     2401 ctggggttgg ttaaggaaga tgttctgaat agaagcattt tggaattgct caagatagaa
     2461 gaaaactatg aattgcgtga tttgattacc caaagtccag aattgttgct agattcccaa
     2521 gatatcaatg gcgaatattt gaaccttcga gttcgctttg ccttgatacg tcgagagtct
     2581 ggctttattt caggtttggt ggctgttttg catgatacga cggagcagga gaaggaagaa
     2641 cgcgaacgaa gactctttgt ttccaatgtt agccatgagt tacggactcc tctgactagc
     2701 gtaaaatcct atcttgaagc cttggatgag ggggctttgt gtgaaactgt agcaccagac
     2761 tttatcaagg tttctcttga tgagaccaac cgtatgatgc gcatggtgac ggatctcctc
     2821 catctttcac gtattgataa tgctaccagt cacctagatg tggaactgat taacttcact
     2881 gcttttatta cctttatcct caatcgtttt gacaagatga aaggacagga aaaggagaaa
     2941 aaatatgagt tggtgagaga ttatcccatc aattctatct ggatggaaat tgatacagat
     3001 aagatgacgc aggttgtcga caatatttta aataatgcta ttaagtattc gccagatggg
     3061 ggtaaaatca ctgtcagaat gaagacaact gaagaccaga tgattttatc catttctgac
     3121 cacggtttgg ggattcctaa gcaggattta ccacgtatct ttgaccgttt ctatcgtgtg
     3181 gatcgtgcta gaagtcgtgc acaaggtggt acaggtctag gactgtctat cgctaaagaa
     3241 attatcaaac aacataaggg ctttatttgg gccaagagtg aatacggcaa gggttcaacc
     3301 tttaccattg tgctccctta tgataaggat gcagtgaaag aagaagtatg ggaggatgaa
     3361 gtagaagact agaatgagtg aaataggctt taaatacagt attttagcgt cgggttccag
     3421 tggaaattct ttttatctgg aaacctcaaa aaagaagctt ttagtagatg caggcttgtc
     3481 tggcaagaaa attaccagtc tgctagctga aattaaccgt aagccagaag acctggatgc
     3541 catcttgatt acccatgagc attcagatca tatccatgga gtaggcgttt tggctcgcaa
     3601 gtatggtatg gatctttatg ccaatgaaaa gacctggcaa gctatggaaa atagtaaata
     3661 tcttggcaag gtggattctt cgcaaaagca tatttttgaa atgggtaaaa ccaaaacctt
     3721 tggagatatc gacatcgaga gttttggtgt aagccatgat gcagtcgcac cgcagttcta
     3781 tcgctttatg aaggatgata agagttttgt cctcttgaca gatacaggtt atgtcagtga
     3841 ccgtatggcg ggcattgtcg aaaatgcgga tggttatctt atcgaggcca accatgatgt
     3901 agagattttg cgatcaggtt cttacgcttg gcgcctcaaa caacgaatcc tatctgacct
     3961 tggtcacctt tctaacgagg acggtgctga agctatgatt cggacgctag gaaatcgtac
     4021 taagaagatt taccttgggc atttatctaa ggaaaacaat atcaaggaac tggctcatat
     4081 gaccatggtc aatcagctgg ctcaagctga tctgggagtc ggagtagact ttaaggttta
     4141 tgatacctca ccagataccg caacaccatt gacagagata tagaaagaac gctgagaagg
     4201 tgttcttttt atattgactg gacacctaaa aagtaataca atggtgttac cattaaaaaa
     4261 gggagcacaa aagatgacta ctattacatt aaaagtttct gaagctgata aaacatttat
     4321 gaaagcaatg gctaagtttg aaggagtttc cctttcggaa cttattcgca ccaaaactct
     4381 tgaagcccta gaagatgaat acgatgctcg tgtggcagat ttagcctatc aagagtattt
     4441 agaagacttg gaaaaaggag ttgaacccat tacttgggaa gaaatgatgc atgatttagg
     4501 cttgaaggat gaataatttg tataaattag ttccaacaag acgttttatc aagcaattga
     4561 aaaaattgga ccgttatacg cagaagctaa ttacaaacta tttacaaacc aatgttttgg
     4621 aagatccaag acgacacgga aaggctttgg ttggtaatcg cgttggtcaa tggcgctata
     4681 gaattggtaa ttatcgagtt atcgtacaaa ttgtagatga tgaattagtt gttgctactc
     4741 tagaagttgg tcatcggaga gatatttatt gaattaaagc tgagtaataa caatatagaa
     4801 agtaaggaga gtaaaaattt gaagaaaaaa tggttttttg cagattatta tgatacaaca
     4861 attattttac ttgctttaat ctctgttatt ctggtattac ttggatttgc tgagatgatt
     4921 gatttggaca atccgcctta tagtattatt gatttagtaa tctggggtgt ttttgtaatt
     4981 gattatagtt ggcgcttttt tacgactaaa agaaaatggc gctttattct tgaaaatatt
     5041 tttgatttat tggctattct ccctttaaat gctattttta cagtgtttcg attagggcgt
     5101 atctttcgtt tagttaaact aacaaaatta ctgaaactga ctcgtttact tagaataatt
     5161 ggacttacag gtaaattaga aagaaaaatt agtagattct tacggacaaa tggcttgatt
     5221 tatatcttgt atgttaatat ctttatcgtg ctagtaggaa gttcaatttt atctgtagtt
     5281 gaagaaaaat ccttctcaga tagtctttgg tgggctcttg taacggtaac gactgttgga
     5341 tatggggata ttgttcctgc ttccattttt gggaaatggc tagcagtttt actgatgctt
     5401 gtcggtattg gaacaatagg gatgttaaca agtgctttga cgaacttttt tgtaaaggat
     5461 aatccagatg aacagataaa acttgataaa ctccaagatg aattatctag tcagagaata
     5521 ttactagaga aacaatctaa aaagatagaa gaactacata aaatgataca agatttgatt
     5581 gaaaaaacat aataaaaata aagatgagaa aaagtttgaa ctgaggagaa atcaagtaag
     5641 ttttgacaca atagaacgca ta
//
LOCUS       DAVHSI010000073         5170 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.076, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000073 DAVHSI010000000
VERSION     DAVHSI010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.076"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..622)
                     /locus_tag="VVR21_002035"
     CDS             complement(<1..622)
                     /locus_tag="VVR21_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEU6055823.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDNNTSNEEARIKE
                     DSNQSQGDNAHSSANKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGV"
     gene            843..929
                     /locus_tag="VVR21_002036"
                     /pseudo
     CDS             843..929
                     /locus_tag="VVR21_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(1355..1552)
                     /locus_tag="VVR21_002037"
     CDS             complement(1355..1552)
                     /locus_tag="VVR21_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU6055824.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
     gene            complement(1537..1755)
                     /locus_tag="VVR21_002038"
     CDS             complement(1537..1755)
                     /locus_tag="VVR21_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU6055825.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(1853..2638)
                     /locus_tag="VVR21_002039"
     CDS             complement(1853..2638)
                     /locus_tag="VVR21_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055826.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(2640..3458)
                     /locus_tag="VVR21_002040"
     CDS             complement(2640..3458)
                     /locus_tag="VVR21_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU6055827.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(3460..4452)
                     /locus_tag="VVR21_002041"
     CDS             complement(3460..4452)
                     /locus_tag="VVR21_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6055828.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
BASE COUNT         1686 a         1068 c          860 g         1556 t
ORIGIN      
        1 caactccaat ttcctttctg gcatgattca tcatgggttg gactttttgt gccctttcaa
       61 ccgatgaaat accttctatt tgtttaattt tgtccaagtt atctggagtt gtttctatgg
      121 cactaccgtt aaaaattcta tcataagtat ataaaacttt tgtattctta agactggata
      181 gttgcttgat tgctttttct ccagattctt tatctttaaa ttcagcaata tagacaactt
      241 tatcttcttt tttgggattt tctgtgtttt tatttgcaga cgagtgtgca ttatctcctt
      301 gagattgatt ggaatcttct ttgattcttg cttcttcatt gctagtgtta ttgtctatca
      361 caggattttt actaacaact tctttttcct caataattgt tgttttcttt tcttcagtat
      421 cctttgaagt ttctatagca ttatgaatat ctttatgttt ctctttattt tctgtttcct
      481 tatctactac tactttttct ttatcagaga tgcttaaagc atcttcagag ctagatgtgt
      541 ctgctaagac tacctcatta ggggcatagg ctgctaaaat aactgcagct gtggttaatg
      601 acaatactgt actttttttc attttaattc cttacatatt tatataactt ccaatagata
      661 ataaacttta actttgctag cctttgttat aaaaagtttt actaagtatt atctaggaaa
      721 tagagtagta catttatata taattgttat ctctccataa aaacagtata tcatttaaaa
      781 aaatttaatt caagaaaaat taacctgcat taatttattt tttagcacac gttaaaaaat
      841 aagattagta ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa
      901 aacactgttt tgaggttgta gatgaaactg acgaagtcag ctcaaaacat ggttttgagg
      961 ttgtagatag aactgacgaa gtcagtaacc atatatacgg caaggcgacg ctgacgtggt
     1021 ttgaagagat tttcgaagag tataagtcca aaactttcgt taaccgggat acattataag
     1081 cacattcata ccatcaaaaa tagtagcaat aaacttgaac aactaccaga aacacgaaaa
     1141 caggcataat tgatgaaata tcagcgctat taaacaatat aaataaccgc taagaataag
     1201 gcttaacggt tatcttctac ctatctattt tttcaactcc tcagtcgttt atctacctat
     1261 aacctaggct ttacgagtgc cttgctctac caactgagct aaatcggcga ttacacttac
     1321 agtatagcac tctgagaata gatgtcaagt aatattattc aagcttttta atcaaaatct
     1381 gacaaggatt ttgcggattc catagctgag aaaaaatctc taacttttta aagccaagac
     1441 ctcgataaaa gtcatttgtt cgatcataat ctttattaga accttctgcc actgttttga
     1501 cctgcagata accaactttt ttacgagctt cactctctaa agtagcaagc aattggctcc
     1561 caatttttct accttgataa gcttttttac gccgagacaa tcaatctctg cacaatcttc
     1621 actcgaatag gataacctta caaatccagt caaatcactc tcctgatagg cggtccaaac
     1681 ttgcagtgtc gtggttcctt ctatataggc ttgtgtgctt tctgggattc caaaccattc
     1741 tggcaaatcc ttcaaaacct cagcgacaac tgcctttttt gattttcatc cttgacttct
     1801 tcaattacaa acatcataag ttcctttctt gattttagtc ttactttagc ttttacgaac
     1861 ccgcactttc gtaggaatct aagcccttat cccaaagttt aagggaaata acaaagaaaa
     1921 ccagagaaat caacatcaaa cctcctacgt taaagaacac atccttttcc tgtaagaaat
     1981 agctagctgg atagtaggct gtaaaggcga aaggcacgat aaagctaatc aaccaacgaa
     2041 gaagagaatt gtaaatagaa atcggatact tagcaaagtc attgaacata tagaagatgt
     2101 aaatcatggc gcctgactgc ttagtccaaa aggcgatact ggctgttgcg attttaagag
     2161 aagtataaat caaggtcgca aaaggaatac aaactaggaa aagcaggaat tttggaagag
     2221 tccaaacaat gctggtcact gttgttccca ataaaatacc accgactaag agttcaccca
     2281 aggcatcaat ctgaaaggtt tcaactagga tatgaaagag aggattgatg ggacgagtca
     2341 gatacttgtc aaactcccct tttcggacta ggcgttgccc tagtgcccag agattgtcaa
     2401 aaaagagatg gtccattccc ttgggaatca aggaaaatcc ataaatgaaa gctatctctt
     2461 gaaaggtcca gccttctagg aatggaatat gttgaaagat gacattgaga aacaagagat
     2521 tcaagccttg agccagaaag actcccaaga caccaaccac aaaatccacc ttatattcca
     2581 tgatttgttt gatgtattgt ctgataaaaa tcagatgcat tcgttgatat tttttcatac
     2641 taacctcctt gaatggtgat aaaggactgg acccgtttcc aaatcaactg agacaatccc
     2701 accatcacta agagccagaa gaactgcaaa aggagtgcct gaagaatctg actggcatcg
     2761 tattttccaa caatgatcat aactggagta taaatcaagg atgaaaaagg caaaaaggag
     2821 agaatatctg aaacaacctt tggaaagaat gccaagggaa tcaaactccc cgacataaaa
     2881 gccactatgg aagtcttaag taggttggaa ccccaaagat ttttaaacac aaaggctgaa
     2941 aatccaaagc aaatattaaa gaaaaagtta atcagatagg cgagcgttaa gctaaaaaga
     3001 taaatgacag ttaatcctag cacctctaca ataccttgac ccgatatgat tttcatcaag
     3061 acaatgacac ttaaaaatgg aaggccaacg ctgataaaaa tcaaccactt ggaaccaagc
     3121 tcggtgaaaa gataggaggc cgcaaaatgc actggtcgca acaaacgcat gataatggag
     3181 ccatccttga cctcctcccc aatcataaag gacgaatcgg atctagtcag aagattggtc
     3241 acaaaactca tgatgatgta gagggtgata tccgccatac tgaagccctg aatcaaagac
     3301 tcttgcgaag aatcaaagac agccttccag agataaaagg ccacaaaagc ccccatgaca
     3361 tcgccaatcc gatagagaat aaagttgact cggtaagtaa tcaactcctg aacccctgca
     3421 ttgataaagg gtttataacg tctccacaat ttgatcatcc tagagctcct ttcggtagaa
     3481 gcgacggata atatcctcaa tatccgtatc caccatcttc aaatcgcgga tttcaaaatc
     3541 agacagggtt tgcttgataa tgtcagctga ctggtagcga gaactatcaa attcaatgtt
     3601 gaggctgttt ccttgtctat caatggtcat atcagacaga ccgtcatagt gagagacgag
     3661 atgactttga cctggtagca gttcaaaaga gagagtcttc atcttaccaa aggtctcctt
     3721 gagttggctc accgttccat caaaaatctc ttgccccttg tcaatcatga aaatccgatc
     3781 acaaagttgc tcaatatcac tcaaatcgtg agtggtcaaa agaatggtag tttcttcctc
     3841 ttgattgatc tgagtaattg cccgacgaat attatcctta accgaaacgt ccaaaccaat
     3901 ggtcggctca tctaaaaaaa gaaccttggg attgtggagc aaggaggccg caatatccgc
     3961 ccgcatccgt tgtcccagtg aaagagtccg cacgggatcc ttgataaagt ccttcaaatc
     4021 caagacttca ttcaaaaagt ccatacgctt atgaaagagc gagtctggca catcataaat
     4081 ctcttttaag acagtgtagg tctcttgcag agccaaatcc caccatagct gggtgcgttg
     4141 tccaaagact acgccaatat ctttgacata atcttgccga ttgtcctggg gaatcttgcc
     4201 gttaatccga caaaaaccag atgttggttt caaaattcct gtcagcattt taatggttgt
     4261 cgacttccca gcaccatttg ccccgataaa tcctaaaatc tgcccttttg gaacctcaaa
     4321 ggtcaaatcc ttgaccgctt caaaggtctg cttttcagga tgaataaagg agcgcaaagc
     4381 ccccttcaag cccggttcct taacagtctt cacaaaattt ttctgaagat gttccacttc
     4441 tatcattgcc atatctatct ccctatcgta aggaatagca acattgtgtt tttaactaca
     4501 aatattctaa atccttgctt tctacacctt ctacatttta ttactacaaa aggctttata
     4561 ccaacctatt atagtccaat aaaaaacgaa atgcaagagt ttgcctatgg attgtgaaat
     4621 taggatttct ctcatgaaat aatactttta atcaaaaatt ctgtttaata gtttaaatta
     4681 ccaacctact catcttctca ccagagggcg gtattaactt tgatcataaa atcggatact
     4741 ccctctatcc agaaaatatg ctcagaatga ttgtctctaa acaatacctg ctcttttacc
     4801 tcattcatga aaaagaagtc cataccctga gaattatcaa ctcacgcacc gactacctaa
     4861 accaactcga ccacctcttt cgtacatgta ggaaactatt ttcctcacaa ataatctcat
     4921 tataaaatcc aataaatttt ttagctcact tgaatatttt ctttgtatcg ttttatcagc
     4981 ttcaatctga tctagacttg ttaccttgga acgacttgaa ataaccttta taaaataaca
     5041 cttaagactt tcatcatttc gtataaattt ttcaatagtg atataaaaag ctttcatatt
     5101 ctgtttgtaa tcagatatca attgattaat tttatcattc tgatgaagat tcgataccat
     5161 aatatatagc
//
LOCUS       DAVHSI010000074         4730 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.077, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000074 DAVHSI010000000
VERSION     DAVHSI010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4730
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.077"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..1537
                     /locus_tag="VVR21_002042"
     rRNA            <1..1537
                     /locus_tag="VVR21_002042"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1589..1661
                     /locus_tag="VVR21_002043"
     tRNA            1589..1661
                     /locus_tag="VVR21_002043"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1622..1624,aa:Ala,seq:tgc)
     gene            1786..4687
                     /locus_tag="VVR21_002044"
     rRNA            1786..4687
                     /locus_tag="VVR21_002044"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1305 a          972 c         1410 g         1043 t
ORIGIN      
        1 agtttgatcc tggctcagga cgaacgctgg cggcgtgcct aatacatgca agtagaacgc
       61 tgaaggagga gcttgcttct ctggatgagt tgcgaacggg tgagtaacgc gtaggtaacc
      121 tgcctggtag cgggggataa ctattggaaa cgatagctaa taccgcataa gagtggatgt
      181 tgcatgacat ttgcttaaaa ggtgcacttg catcactacc agatggacct gcgttgtatt
      241 agctagttgg tggggtaacg gctcaccaag gcgacgatac atagccgacc tgagagggtg
      301 atcggccaca ctgggactga gacacggccc agactcctac gggaggcagc agtagggaat
      361 cttcggcaat ggacggaagt ctgaccgagc aacgccgcgt gagtgaagaa ggttttcgga
      421 tcgtaaagct ctgttgtaag agaagaacga gtgtgagagt ggaaagttca cactgtgacg
      481 gtatcttacc agaaagggac ggctaactac gtgccagcag ccgcggtaat acgtaggtcc
      541 cgagcgttgt ccggatttat tgggcgtaaa gcgagcgcag gcggttagat aagtctgaag
      601 ttaaaggctg tggcttaacc atagtaggct ttggaaactg tttaacttga gtgcaagagg
      661 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccggtgg
      721 cgaaagcggc tctctggctt gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      781 gattagatac cctggtagtc cacgctgtaa acgatgagtg ctaggtgtta gaccctttcc
      841 ggggtttagt gccgtagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      901 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      961 agcaacgcga agaaccttac caggtcttga catccctctg accgctctag agatagagtt
     1021 ttccttcggg acagaggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
     1081 ttgggttaag tcccgcaacg agcgcaaccc ctattgttag ttgccatcat ttagttgggc
     1141 actctagcga gactgccggt aataaaccgg aggaaggtgg ggatgacgtc aaatcatcat
     1201 gccccttatg acctgggcta cacacgtgct acaatggctg gtacaacgag tcgcaagccg
     1261 gtgacggcaa gctaatctct taaagccagt ctcagttcgg attgtaggct gcaactcgcc
     1321 tacatgaagt cggaatcgct agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg
     1381 ggccttgtac acaccgcccg tcacaccacg agagtttgta acacccgaag tcggtgaggt
     1441 aaccgtaagg agccagccgc ctaaggtggg atagatgatt ggggtgaagt cgtaacaagg
     1501 tagccgtatc ggaaggtgcg gctggatcac ctcctttcta aggataagga actgcgcatt
     1561 ggtcttgttt agtcttgaga ggtcttgtgg ggccttagct cagctgggag agcgcctgct
     1621 ttgcacgcag gaggtcagcg gttcgatccc gctaggctcc attggtgaga gatcaccaag
     1681 taatgcacat tgaaaattga atatctatat caaatagtaa caagaaaata aaccgaaaac
     1741 gctgtagtat taataagagt ttatgactga aaggtcagaa aataaggtta agttaataag
     1801 ggcgcacggt ggatgccttg gcactaggag ccgacgaagg acgtgacaaa cgacgatatg
     1861 ccttgggtag ctgtaagtaa gcgatgatcc agggatttcc gaatggggga acccaacagg
     1921 tagtacctgt tacccacatc tgttaaggat gtgaggagga agacgcagtg aactgaaaca
     1981 tctaagtagc tgcaggaaga gaaagcaaaa gcgattgcct tagtagcggc gagcgaaacg
     2041 gcaggagggc aaaccgaaga gtttactctt cggggttgta ggactgcaat gtggactcaa
     2101 agattataga agaatgattt gggaagatca gccaaagaga gtaatagcct cgtatttaaa
     2161 atagtctttg tacctagcag tatcctgagt acggcgggac acgtgaaatc ccgtcggaat
     2221 ctgggaggac catctcccaa ccctaaatac tccctagtga ccgatagtga accagtaccg
     2281 tgagggaaag gtgaaaagca ccccgggagg ggagtgaaat agaacctgaa accgtgtgcc
     2341 tacaacaagt tcgagcccgt taatgggtga gagcgtgcct tttgtagaat gaaccggcga
     2401 gttacgttat gatgcgaggt taagttgaag agacggagcc gtagggaaac cgagtctgaa
     2461 tagggcgcct tagtatcatg acgtagaccc gaaaccatgt gacctaccca tgagcaggtt
     2521 gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag tgcttggatg
     2581 acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata
     2641 gctttagggc tagcgtcgac attagagatt cttggaggta gagcactgtt tgggtgaggg
     2701 gtccatcccg gattaccaat ctcagataaa ctccgaatgc caatgaatta tggtcggcag
     2761 tcagactgcg agtgctaaga tccgtagtcg aaagggaaac agcccagacc accagctaag
     2821 gtcccaaaat aattgttaag tggaaaagga tgtggggttg cacagacaac taggatgtta
     2881 gcttagaagc agctattcat tcaaagagtg cgtaatagct cactagtcga gtgaccctgc
     2941 gccgaaaatg taccggggct aaaacaattt accgaagctg tggatacctt tataggtatg
     3001 gtaggagagc gttctatgtg tgatgaaggt ataccgtgag gagtgctgga acgcatagaa
     3061 gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc gtaagactaa
     3121 ggtttccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag agaccgaaag
     3181 gtgtatccga tggacaacag gttgatattc ctgtactaga gtatgtagtg atggagggac
     3241 gcagtaggct aactaaagca gacgattgga agagtctgtc taagcagtga ggtgtgaatt
     3301 gagtcaaatg cttaattcta taacattgag ctgtgatggg gagcgaagtt tagtagcgaa
     3361 gttagtgacg tcacactgcc aagaaaagct tctagcgttt aaacatactc tacccgtacc
     3421 gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg agcgagagaa ctctcgttaa
     3481 ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg tgctgacttt aagtcagccg
     3541 cagtgaatag gcccaagcaa ctgtttatca aaaacacagc tctctgctaa atcgtaagat
     3601 gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc ttagcgtaag
     3661 cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt cctaaggtag
     3721 cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt tgggcactgt
     3781 ctcaacgaga gactcggtga aattttagta cctgtgaaga tgcaggttac ccgcgacagg
     3841 acggaaagac cccatggagc tttactgcag tttgatattg agtgtctgta ccacatgtac
     3901 aggataggta ggagtctaag agatcgggac gccagtttcg aaggagacgc tgttgggata
     3961 ctacccttgt gttatggcca ctctaaccca gataggtgat ccctatcgga gacagtgtct
     4021 gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc ccaaaggttc
     4081 cctcagaatg gttggaaatc attcgcagag tgtaaaggta taagggagct tgactgcgag
     4141 agctacaact cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc cgtatggaag
     4201 ggccatcgct caacggataa aagctaccct ggggataaca ggcttatctc ccccaagagt
     4261 tcacatcgac ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg gggctgtagt
     4321 cggtcccaag ggttgggctg ttcgcccatt aaagcggcac gcgagctggg ttcagaacgt
     4381 cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg atctgctcct
     4441 agtacgagag gaccagagtg gacttaccgc tggtgtacca gttgtcttgc caaaggcatc
     4501 gctgggtagc tatgtaggga agggataaac gctgaaagca tctaagtgtg aaacccacct
     4561 caagatgaga tttcccatga ttatatatca gtaagagccc tgagagatga tcaggtagat
     4621 aggttagaag tggaagtgtg gcgacacatg tagcggacta atactaatag ctcgaggact
     4681 tatccaaagt aactgagaat atgaaagcga acggttttct taaattgaat
//
LOCUS       DAVHSI010000075         4540 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.078, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000075 DAVHSI010000000
VERSION     DAVHSI010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4540
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.078"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(198..1673)
                     /locus_tag="VVR21_002045"
     CDS             complement(198..1673)
                     /locus_tag="VVR21_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU6055829.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(1883..2806)
                     /locus_tag="VVR21_002046"
     CDS             complement(1883..2806)
                     /locus_tag="VVR21_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6055830.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(2820..3749)
                     /locus_tag="VVR21_002047"
     CDS             complement(2820..3749)
                     /locus_tag="VVR21_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6055831.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(4068..4289)
                     /locus_tag="VVR21_002048"
     CDS             complement(4068..4289)
                     /locus_tag="VVR21_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055832.1"
                     /translation="MTGVSNPTTDSAPLVLAEAKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKIDNLKEVIAKLKANA"
BASE COUNT         1406 a          857 c          897 g         1380 t
ORIGIN      
        1 aacgaatgca atttatttga ctggaaattg tagagggttc tcgaaatttc ctgaatggtt
       61 aaaataagga caagagaaaa catggatatc tatatccttg tgccaaaaaa accactgccc
      121 tccccagacc aacctgagga aagcagtgat tcttatttta ggagttagga atgaatacac
      181 gaaatcaatt tagctgatta ttttttgttt ttcaagaatt catcgtattg tttttgcatt
      241 tcgttcaata ctttttcgta ggcaccttca gatttcaatt tttccatcaa ttctggaata
      301 gctttatctg ggtctacagt accagtgttg atagctgtat caaattgttg cattgtgtta
      361 gcaatagctg agatttcaga tttcacattg tcagtattga agataaatcc aagcgctgga
      421 gattctttag cttctgccaa ttctttctta gaattttcga tttgttggtc tgtaacgttt
      481 tcgttgatgt aaaggatcca gttgttacca gtgttccatc cacccatgtg agtgtttcct
      541 ttgtagccat caagaacgcg aacacggttt tctttacctt caattttttc ccagttcttg
      601 ccttctggac cgtaaacaag accgttcaag agttctggat tcgtattcaa gaggttcaag
      661 atttccattg atttttcttt gttcttagag ttgtttgaga tgacaaagtt agcaacttgt
      721 gttgtttggt ttttcttgat gaagttagta attggtttga tttggatatc tttgttggca
      781 acacgtgaaa gcaagctgtt accgtagtca gctggtccta ctgtttcttc acgaacgaac
      841 caagtatctt gttgaaggtc aaaggaagta tcgcttgttg cgacgtcttt tggaatgtag
      901 ccagcttcat agaatttgtg aagagtcttc aagtgttctt tgaaacgagg cacttcgtaa
      961 cggtttacaa ctttagtagt atcgccttca aggtcgataa cgaatggaag accgtttgct
     1021 actgggtagt caaagttatc agatgggatg aaaactttac caatagcaaa tggtactacg
     1081 tctggagctt tttctttaat ttgtttcaag actggctcaa gagtttcgta agaagtaaca
     1141 cctgaaatat cgataccata tttagcaagg agagttccgt tgaaggcaaa gttttgagat
     1201 gacgcaacgt tggctgcaac tggaacagcg taaatcttac catttacagt attacccttg
     1261 atgtaagctg ggtcaagtgc tttgtaaagg tctttacctt cttttttgta caattctgtc
     1321 aagtcagcgt aagcaccttt ttgagcattt acaatatagt tatctgcaaa ggcaatatca
     1381 tagttttcac cagatgatgt gataactgac attttcttac catagtcacc ccagccaagg
     1441 tattggatat ccaatttggc accaactttt tcttcaatga ttttgttggc atttgctaac
     1501 aattcatcca agttgtctgg tttgtcaccg atttggtaca ttttgataac aggtttgtca
     1561 cctgaatcag cagctttttt actgttacct gtcaagttgc cacaagcagc aagacctgca
     1621 gccaaagcga ctacactagc agatgcaaaa gcatattttt tccagttttt catgataaaa
     1681 actccttttt ttatttttaa acttataaac aatgtaatga tcttatactc aatgaaaatc
     1741 aaagagcaaa ctagaaaact agccgcaggc tgtacttgag tacggcaagg cgacgttgac
     1801 gcggtttgaa tttgattttc gaagagtatt aacttcacac aagggaagtt gggaactgag
     1861 aaatgttctt tttcaataag cactattctt tcacaccacc gatagtcaaa ccttttacaa
     1921 agtagcgttg gaagaatgga tataaaatcg cgattggaag ggttgcaacc acaaccatgg
     1981 ccatacgacc tgtttctttc ggtagagcaa ctcccagttg accagtcaag ccgaccgctt
     2041 tggcaatgta gtccatattt tgttggattt gcatgagcaa atattgcaat ggatacaagt
     2101 tatcactctt gatgtaaaga agggcgttga accagtcatt ccagaaacca agagctgtca
     2161 aaagcgtgat ggttgcgata cctggtagtg acaatggcaa acagatttgg aagaaaatcc
     2221 gggcctcact ggcaccatcg atacgagccg attcgagaat ggcttctgga atggtcttct
     2281 tgaagaagga acgcatcaag atgatgttaa agggggagag aagcattggc acaatcaagg
     2341 cccaaacagt gtcaccaagc tgaagtacac gggtcaccat gatataacct ggtaccaaac
     2401 cagcgttgaa caacatactg agaaggacga agatggtaaa aaatctgcga tacttaaagg
     2461 ttgtccgtga aatagcgtag gcataggttg ttgtgataaa gacatttgtc aatgtcccaa
     2521 ctacggttac aaagacagag atgaagaggg cttgtaggat tttatcctta aactgtgcca
     2581 aaaactcaaa accgtctaag ccaaattggg atgggaagaa gctatagccg tattggagga
     2641 ggcttttctc gtctgtcact gaaataatga taacgaatac aaaaggtagg atacaagaga
     2701 gggcaatcaa acccgaaatg atactgaaga agatatctgc tttcttactg aaggagtgaa
     2761 tgccgacatt atcaattttt tcttttttaa ttttcttttt tgccatattc tcctcctttc
     2821 tagaacaaag ctgagtttgg atcgactcgt cttgcaagca agtttgatag gataaccaga
     2881 atcaaaccaa caacggattg gtaaagaccg gctgctgcag ccataccgat atctgctgtc
     2941 tgagtcaaac cattaaagac atatacgtcc aaaacgttgg ttacattgta aagctgacca
     3001 gcattgtgtg ggatttgata gaagagaccg aagtctgcgc ggaagatatt tccgactgca
     3061 aggatggtca atacagttac aagcggagtc aactgaggaa tggttacgtt gcgaatacgt
     3121 tgccacttgc tagctccgtc cactgtcgct gcttcgtagt aggttggatc aattcccatg
     3181 atcgtcgcat agtacatgac actgctatat ccaaagcctt tccaaatacc taggaaaagt
     3241 aggagatagg gccagatgcc caggtcagcg taaaaattga cttctttgag accaagactt
     3301 tccaatagat gattgaacac ccctttatca atatttagga aggcatctgt aaagaaactg
     3361 atgataaccc aagacaagaa gtaagggaac aacatagaag tttggaaaat cttcaccatt
     3421 ctcttagaac ggagctcgct gaggataatg gcaatcccta cagatacaac taaacctaga
     3481 aagataaagc caagattgta gaggacagta tttcgtgtga taataaaggc gtctcttgaa
     3541 ctaaataaga atctgaaatt atcgagtccg acccatttac tatttatgat actatctatg
     3601 aaaccattac tggtcatgtg gtagtctttg aaggcaacca cgttcccaaa tactggaatg
     3661 taaaagaata gaatcaacca gagtgcccct ggcaaaacca tcaagagaaa gatccagttg
     3721 tctctcaatg tttttgaaaa ctttttcata atttcctccc tttttatttt gatatccatc
     3781 taaaaattct tttttagact tttgataacg attacattat tagtatactc ctatttgcag
     3841 gttaggttaa actcctaatt atagaaaaaa ctccacaaat tatgtagcag atttaaaact
     3901 ttatcaccac tatcaaacaa atgtcctaaa tcaattgttt attttatctc tattagccca
     3961 gtgatggcgt cactctgtta taagtatcca acaacggggt atactgaaaa atctccagac
     4021 tagggaactc agcgatagtt cctaatctgg agatttttaa tatgttatta ggcgtttgct
     4081 ttcaacttag caataacctc tttaagatta tcaatcttag ttgctgactg gctttcctta
     4141 atggactcta gggaagcaat ggcatctttg actgtttgca agatatcacg taaaccttgc
     4201 tctatcaaac tatcatctgc aaaagctttc ttagcctctg ccaaaaccag aggtgctgaa
     4261 tctgtggtag gattcgatac acctgtcaat gatctcaaaa gattttctaa ggtttgagtc
     4321 tgcttactaa tactagacta aaatcaaaaa gcattatata acagtgatat gaaatcaact
     4381 aaagaagaaa tccaaaccat caaaacactt ttaaaagact ctcgtacagc taaatatcat
     4441 aaacgccttc aaatcgttct atagtaaaat gaaacaagaa caggacaaat cgatttctaa
     4501 caatgtttta gaagtagagg tgtactattc tagtttcaat
//
LOCUS       DAVHSI010000076         4322 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.079, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000076 DAVHSI010000000
VERSION     DAVHSI010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.079"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            127..1530
                     /locus_tag="VVR21_002049"
     CDS             127..1530
                     /locus_tag="VVR21_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU6055833.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLLSQGKINEDTELK
                     DIMTNIADTKYYYPQLS"
     gene            1560..2852
                     /locus_tag="VVR21_002050"
     CDS             1560..2852
                     /locus_tag="VVR21_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6055834.1"
                     /translation="MNKKSLLKCAVIGLVATFGLAACGTSKDASGGSSSGKEVLEFYH
                     GYHHSEDEWPVAKTMRDLYDKFAEEHKDSGVEFKPTPVNGDLKDIMNNKVASGEFPDV
                     IDLAGNAVSLAAIEQKLVLDLKPYIDSNKLEKNVGLNYKQNQKDGKIYTVHEQLFTMG
                     LWYNKDIFAKAGAKTPDQWNTWDDFTQAMASIRKQDGVYAFGAGEPSIRLFNTVLGTT
                     ENGRKLLDKPLTKEGIESKEFADALKMVMKEIQANGSKNAGGDANAYSKDFQEGKSAV
                     FFNGVWASGEMSKNPSLAPGIYPAGVAISSSGGGITISSKMSEAKQKLALEFLKYMTS
                     DDVQKVIFEKVGANPSNENVNVKELSEKSSEATTKILGQAITQVKNAKAVVPTVSDVW
                     GGDVHTAIINALTESAAENVDVDQKVKSTQDVLKSLIG"
     gene            2940..3869
                     /locus_tag="VVR21_002051"
     CDS             2940..3869
                     /locus_tag="VVR21_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU6055835.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            3872..>4322
                     /locus_tag="VVR21_002052"
     CDS             3872..>4322
                     /locus_tag="VVR21_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU6055836.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPTDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSC"
BASE COUNT         1453 a          582 c          873 g         1414 t
ORIGIN      
        1 gaatttgaat tatttttatg aatattgggt taacatttga acattattca agtaagcgtt
       61 cacatattga aaaaataaaa tgtggggatt ataataaagt taatcaagga cgaagagaga
      121 agaaaaatgg aagcggtttt agcaatagat ttaggtgcga cttctggaag agcaatcgtt
      181 ggttaccttt ctgaaaataa actagtaatg gaagaaataa atcgcttttc taatctacct
      241 attagagtaa aagggcattt atcttgggat attgactttc tactagctaa aattcttgaa
      301 agtatccgct tggctaatac tagttacaag attttatcta tcggtattga cacatgggga
      361 gttgattttg gactgattga taatgaaggt aagctgttat cacaacctgt tcattatcgt
      421 gatgaaagaa caaagggagt gttaaaggaa atatctgaaa tgactgaatt agaaaaactg
      481 tattcagaga caggaaatca gattatggag ataaatacct tgtttcaact ctttaaggca
      541 cgtcaagaat ctcctgactc tttctataag accaataaga ttcttttaat gccagatttg
      601 tttaattatc tcttgacagg taagtttgct acagaaaaaa gcattgcttc aacaactcaa
      661 ttatttgatc ctaggagtca aaattggaat cagaatatct taaaactatt tgaattggat
      721 tcatctttac ttcctgaaat tgtttcagag ggaaatgttc ttggaaggat aaaaaaggag
      781 tatggtttag gcgatattcc tgttgtgaat gtttgtagtc atgatacagc aagtgcgatt
      841 gtctcagtac ctaagacaga aggtagttta tttatttcat caggtacttg gtctttggtt
      901 ggagtggaac ttacttcacc gattcttact accgaatcct tcagttatgg atttacaaat
      961 gaagtcggta aagatggaga gattacattt ctgaagaatt gtacagggtt gtggatcata
     1021 gaggaactaa gacgttcatt tgaacgaaga gggaaagcct attcttttga tgatattagg
     1081 acaatggtgg agaaagaaaa agaaaatctt cctctgattg atactgaatc aactgaattt
     1141 gcaacagaat ctgatatgca caagactttg acagaatatc tagcttatca tcatgaaact
     1201 agagagtgga cagatggaca actatttaag attgtttatg aaagcctagc tgaaacgtat
     1261 aggaaagcga tagagttatt agaagaacta actcataagg tttataagag gatatatgtg
     1321 attggaggag gtgctagagc cagttacttt aaccaaatga ttgctgatag aactggtaaa
     1381 gaggttctta caggttcgac tgagggtaca gctgtgggga atattgttgt gcagctattg
     1441 agtcaaggta aaataaacga ggatacagag ttaaaggata ttatgacaaa tattgctgat
     1501 acaaaatatt attatcctca gctatcataa acaaaaataa aaaaaacgga ggttttgtca
     1561 tgaacaaaaa aagtcttttg aaatgcgctg ttatcgggtt agtagctacc tttggtttag
     1621 cagcttgtgg aacatctaag gatgcaagcg gtggaagttc ttctggtaaa gaagtattag
     1681 aattttatca tgggtatcat catagtgaag atgaatggcc tgtagcgaag actatgcgag
     1741 atttatatga taaatttgca gaagaacata aagatagtgg tgtagaattt aaaccaactc
     1801 ctgtaaatgg tgatttgaag gatataatga ataacaaggt tgctagtggt gaatttcctg
     1861 atgtgattga cctagcaggt aatgcagtat cattagctgc gattgaacaa aaacttgttt
     1921 tagatttgaa accatatatc gattcaaata agcttgaaaa aaatgttggt ttgaactata
     1981 agcaaaacca aaaagatgga aaaatttata cagttcacga acagttattt acaatgggtt
     2041 tgtggtacaa caaggacata tttgcaaaag cgggtgctaa gacacctgat cagtggaata
     2101 cttgggatga tttcactcag gcaatggcaa gcattagaaa acaagatgga gtgtatgcat
     2161 ttggtgctgg agaaccatct attcgcttgt ttaatacagt attaggaacc acagaaaatg
     2221 gacgtaaatt attagataaa ccattaacaa aagaaggaat tgaatctaaa gaatttgcag
     2281 atgctttgaa aatggttatg aaagaaattc aagctaatgg ttctaagaat gctggtggcg
     2341 atgccaatgc ttattccaaa gatttccaag aaggtaaatc tgcagtattc tttaatggtg
     2401 tgtgggcttc tggtgagatg tctaagaacc caagtcttgc acctggaatc tatcctgcag
     2461 gtgtagcaat tagttcttct ggaggtggta tcactatctc aagtaagatg tctgaagcta
     2521 aacaaaaact agctcttgag tttttgaaat atatgactag cgatgatgta caaaaagtaa
     2581 tttttgaaaa agtaggagca aatccttcta atgaaaatgt aaatgtaaaa gaactttcag
     2641 aaaagagttc agaagctact actaaaattt taggacaagc aatcactcaa gttaagaatg
     2701 caaaagcagt tgttccaact gtaagtgatg tttggggtgg cgatgtacac acagctatta
     2761 tcaatgcatt gacagaaagt gctgctgaaa atgtagatgt tgatcaaaaa gtaaaatcta
     2821 ctcaagatgt gttgaaatca ttgattggtt aattgtttta gggagtgaaa acgaagctca
     2881 gttggcactg ccaactgagc ttgattttac ttatatagtt gaaaaaaagg agtttgttta
     2941 tggcacaaaa aattatgagc ctacaaaata ggaagaatca aaaaagacga tttatctttt
     3001 tatttctttt gccaacgttg atttgtttct ttctatttta tttttattct gtagtaacaa
     3061 tctttttaac ttcatttgct aaatgggatt atacaaattt aaacacccct gagtttcttg
     3121 gatttgataa attatttgaa aattataggt atgtttttaa agaataccca ttttttacag
     3181 aagctctaat taattctgtt cgttgggctg taattggtgt tattattcaa gttcctttag
     3241 ctgtatctgt tgcaattaca ttatctaaga aattaaaagg ctggaagata tctaggaatc
     3301 tttatattgt accaagtatc atttctagtg ctgctatggg cttgattttt cttcaaatct
     3361 ataatccaaa ctatggtgtt gttaaccaaa ttattcatct atttaatcca tcgtttaaag
     3421 attcagtact gttgactcca ggattaaata tagtagctat gactggcgct tatatcttct
     3481 ttgcaggagc atcaaccatt atgattcttg ggcaaatttt tgctattcca gaagaagttc
     3541 aagaagctgc tattttagac aatattactg gttggaggaa agagtggtat attacgattc
     3601 cgatgattaa ggggacaatt aaaactgttt caattatggc agcaacttca gggtttttgc
     3661 tctataacga agtattcttt ttgacaaatg gtgctgcagg aacaaaaagt atcagttttg
     3721 ttattcgaga attagcagtg gctagctcac gaactcagta tgctcgtgca aatacaattg
     3781 gagttataca aatcttaggt ggaatgttga ttatcgtttg tattaatatt ttattcagag
     3841 aaagaaaaag actgaaaggt gggaaatgat tatgaataca catataaatg gtattagtaa
     3901 aaaaggcaaa gttcttatat atggttatat gctccttacc attttaattt ctattttccc
     3961 tattgcgtgg atttttttat catcattaaa agcagatcct atgaaaaatc caggtattag
     4021 tttaccgact gactttactc ttgaaggtta tataaatgtt tttacaaaac ttcatgtttt
     4081 cacttacttt tggaatagct ttaaagtagt gtctatatca gttattatta gcattgttat
     4141 gatctccatg tcttcatatg ttattgctag gatggaattt agagggaaga agttggtgac
     4201 ttctatgctg tattctactc tatttattcc agcaacagct atgacttttc cagtttatag
     4261 attagtaaat gagttgggga tttataatac cccagttgct ctaattctgg tctactcttg
     4321 ta
//
LOCUS       DAVHSI010000077         3974 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.082, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000077 DAVHSI010000000
VERSION     DAVHSI010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3974
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.082"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(167..1837)
                     /locus_tag="VVR21_002053"
     CDS             complement(167..1837)
                     /locus_tag="VVR21_002053"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU6055837.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            2067..2756
                     /gene="coaB"
                     /locus_tag="VVR21_002054"
     CDS             2067..2756
                     /gene="coaB"
                     /locus_tag="VVR21_002054"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU6055838.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2768..3319
                     /gene="coaC"
                     /locus_tag="VVR21_002055"
     CDS             2768..3319
                     /gene="coaC"
                     /locus_tag="VVR21_002055"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU6055839.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            3303..3866
                     /locus_tag="VVR21_002056"
     CDS             3303..3866
                     /locus_tag="VVR21_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6055840.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
BASE COUNT         1201 a          891 c          715 g         1167 t
ORIGIN      
        1 ggatagaact gacagagtca gtatcatata cctacggcaa ggtgaagctg acgtagtttg
       61 aaaagatttt cgaagagtat aaatcttatt gatgaactgc ttgcagtctg agaaaaaatg
      121 agcttggata ttatttccaa actcacttaa agtcaatttc aatccactag aacaagccta
      181 gcacagttcc atcgctttca acatccatgt tgagagctgc tggacgtttt ggaagacctg
      241 gcatggtcat aacatcacca gttaaggcaa cgatgaagcc tgcacctaat tttggtacca
      301 attcacgaat ggtaatttca aagttttctg gtgctccaag cgcatttgga ttgtctgaga
      361 aactgtattg agttttagcc atacaaattg gcaatttgtc ccaaccgttt tgaacgattt
      421 gagcaatttg tgtttgagct ttcttctcaa agttcacttt gctaccacga tagatttcag
      481 tgacaatttt ttcaatcttt tcttggacag aaaggtcatt atcgtacaaa cgtttatagt
      541 tagctggatt ttcagcaatt gtcttaacaa ctgtttcggc aagtgctact ccaccttctg
      601 ctccatcagc ccagacacta gccaattcaa ctggtacatc gattgaggca cagagttctt
      661 ttaagactgc aatttcagct tctgtatcag atacaaattc gttaatagct acaactgctg
      721 gaataccgaa cttacggata ttttcaacgt ggcgtttcaa gttagcaaaa cctgcacgaa
      781 ctgcctctac attttcttca gtcagagcgt ctttagccac accaccattc atcttaaggg
      841 cacgaagggt tgcgacaata acaactgcat ctggagatgt tggcaagttt ggtgtcttga
      901 tatcaaggaa tttctcagca ccaagatccg caccaaaacc agcttcagta acagtgtaat
      961 cagccaagtg aagggctgtt gtcgtcgcca aaacagagtt acagccatga gcgatattgg
     1021 caaatggacc accgtgtaca aaggcaggtg taccgtaaat tgtctgaacc aagtttggct
     1081 taatagcatc cttcaaaatc aaagccaagg caccctcaac ctgcaaatca cctacagaaa
     1141 caggcgtacg gtcatagcga taaccaataa cgatattcgc caaacgacgt ttcaagtcct
     1201 cgatgtccgt tgccaagcaa agaattgcca tgatttctga agcaactgta atatcaaaac
     1261 cgtcctcacg tggaataccg tttagaggac caccaagacc aacagtcaca tggcggagcg
     1321 cacggtcgtt caagtccaca acgcgtttcc agaggatacg acgttgatca attcccagct
     1381 cattcccttg gtgcaagtgg ttgtcaatca aggcagaaag ggcattgttg gcagttgtaa
     1441 tagcatgcat atctccagta aagtggaggt tgatgtcttc cattggcaga acttgtgcat
     1501 acccaccacc agcagcacca cccttgatcc ccatgactgg accaagagac ggttcgcgga
     1561 tagcaatcat ggttttcttg ccaatcttgt tcaaggcatc cgcaagacca atggtaagcg
     1621 tcgactttcc ttcacctgca ggtgttgggt tgatggcagt aaccaagatc aatttaccga
     1681 ctggattgct ctcaactgcc cgaattttat caaagctgag tttagccttg tactttccgt
     1741 acaactccaa atcgtcgtaa gaaataccaa gtttctctac aacatcaaca attggcttca
     1801 actcaatact ctgtgcgatt tcaatatctg ttttcattca aaattcctct aacctcttat
     1861 atgataattc attatatcac aaaacaagat ttttaacatc ttaaaactct ctaaacgttc
     1921 gtaaatatct ctgtttttaa gacttttaga gtcctttctt aaattttata tggctttata
     1981 gtttgaaact atagtaaatc ttcgttttta ccaaaaattt atcactttca ttttacttac
     2041 cgcttatttt tgtgtacaat agtgctatga aaattttagt tacatcgggc ggtaccagtg
     2101 aagctatcga tagcgtccgc tctatcacta accattctac aggtcacttg gggaaaatta
     2161 tcacagagac tttgctttct gcagggcatg aagtttgttt aattacgaca aaacgagctc
     2221 tgaagccaga gcctcatcct aacctaagta ttcgagaaat taccaatacc aaggaccttc
     2281 taatagaaat gcaagaacgt gttcaggatt atcaggtctt gatccactca atggctgttt
     2341 ctgactacac tcctgtttat atgacagggc ttgaggaagt tcaggctagc tccaatctaa
     2401 aagaattttt aagcaagcag aatcatcagg ccaagatttc ttcaactgat gaggttcagg
     2461 ttttgttcct taaaaagaca cccaaaatca tatccctagt caaggaatgg aatcccacta
     2521 ttcatctgat tggtttcaaa ctgctggttg atgttaccga agatcatctg gttgacattg
     2581 cacgaaaaag tcttatcaag aatcaagcag atttaatcat cgcgaatgac ctgactcaaa
     2641 tttcagcaga tcagcaccga gctatatttg ttgagaaaaa tcagcttcaa acagtccaga
     2701 ctaaagaaga aattgcagaa ctcctccttg aaaaaattca agcctatcat tcttagaaag
     2761 gaaaactatg gcaaacattc tcttggctgt aacgggttca atcgcctctt ataagtcggc
     2821 agatttagtc agttctctaa aaaaacaagg ccatcaagtc actgtcttaa tgactcaggc
     2881 tgctacagag tttatccaac ctttgacact acaggtactc tcacagaatc ctgtccactt
     2941 ggatgtcatg aaggaaccct atcctgatca ggtcaatcat atcgaacttg gaaaaaaagc
     3001 agatttattt atcgtggtac ctgcaactgc taacactatt gcaaaactag ctcacggatt
     3061 tgcggacaac atggtaacca gtacagctct agccctacca agtcatattc ccaaactaat
     3121 agctcctgct atgaatacaa aaatgtatga ccatccagta actcagaata atctgaaaac
     3181 attagaaacc tacggctatc agctgattgc tcctaaggaa tccctactag cttgtggaga
     3241 ccacggacga ggagctttag ctgacctcac aattatttta gaaagaataa aggaaactat
     3301 cgatgaaaaa acgctctaat attgcaccca ttgctatctt ttttgctacc atgctcgtga
     3361 tacactttct gagctcactt atctttaacc tttttccatt tccaatcaaa ccgaccattg
     3421 ttcatattcc tgtcattatt gccagcatta tttatggtcc acgagttggg gttacacttg
     3481 gatttttgat gggattactt agcttgacgg ttaacacgat tacgattcta ccgacaagct
     3541 acctcttctc tcccttcgta ccaaacggaa acatctactc agctatcatt gccatcgtcc
     3601 cacgtatttt gattggttta actccttact tagtctataa actgatgaaa aacaagactg
     3661 gtctgatttt agctggagcc cttggttcct tgacaaatac tatctttgtc cttggaggaa
     3721 tcttcttcct atttggaaat gtttataatg gaaatatcca acttcttctg gcaaccgtta
     3781 tctcaacaaa ttcaattgct gaattggtca tttctgcaat tctaacccta gccattgttc
     3841 cacgactaca aaccttgaaa aaataaaaac aatctccgct ttcaaacctg aaggtggaga
     3901 ttttgctcta tacagtttct ttttaatgaa atctttacta tagtaaaacg aaataagaac
     3961 aggacaaatc gatc
//
LOCUS       DAVHSI010000078         3959 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.083, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000078 DAVHSI010000000
VERSION     DAVHSI010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3959
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.083"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            234..1880
                     /locus_tag="VVR21_002057"
     CDS             234..1880
                     /locus_tag="VVR21_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU6055841.1"
                     /translation="MYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMN
                     DYPHQFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTS
                     IILITHDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMD
                     KKLHVIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHF
                     FFEDKEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTT
                     IGIVGESGSGKSTIAKSLMKLHDITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMV
                     FQDPYASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKEALKMVNVPVEYLERYPHEF
                     SGGQRQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISH
                     DLGVVKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALAT
                     KRKENEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            1890..3299
                     /locus_tag="VVR21_002058"
     CDS             1890..3299
                     /locus_tag="VVR21_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055842.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDTKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            3304..3792
                     /locus_tag="VVR21_002059"
     CDS             3304..3792
                     /locus_tag="VVR21_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEU6055843.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
BASE COUNT         1354 a          586 c          753 g         1266 t
ORIGIN      
        1 tcatttaaat tgtaaacttt agggattctc tgaagttatg gatgtcgttc caatatgtgt
       61 acgttggaat gttagtgctt atatgggggg aacagaatcc tctcttgatt gaagacaagt
      121 tagccattag gctggtttgt ctctttgtca actgtagtgg gttgatataa tagtattagt
      181 gagtgggata aaagtttcat ttagtttatt cagtacaaat ttaacgggtc aagatttata
      241 caattggtaa tcaaattact gaagtccttc atgaacatta tgacatttct aaagaggagg
      301 caaataaacg tgctatagaa atgttagaaa aacttggaat tcataatgct gcagaacgca
      361 tgaatgacta tccacaccaa tttagtggag ggcagcgtca aagaatagtc atagcgattg
      421 caatggtatg taatccagat attctaattg cagatgaacc aacaactgcc cttgatgtaa
      481 caatccaagc acaaatactt gatttacttg atgatttacg taaagagcat ggaacttcta
      541 ttatcttaat tactcacgat ttaggcgtta ttgctcaaat tgcggatgaa gttgcagtga
      601 tgtatgctgg tgaagtcgtt gaagttggaa ctgtagctca gatctttgat caacctaaac
      661 acccgtatac tcgttctcta ttaagatcta ttcctaatcc tgaaaatatg gataaaaagc
      721 tacatgttat ccaggggagc gtaccttcaa tttctgaaat atctgaaaaa ggatgcagat
      781 tcgcaaatcg tattccatgg ttagaaaaag aacatcatga agaagaacct caattgcatg
      841 atttaggtga cggacatttt gtaaggtgtt cttgctataa acatttcttt ttcgaagata
      901 aggaagaaga aacattagcg gaaaaacatg taggtaatgt tgttttagaa gtaaaaaata
      961 ttaaaaagta ctactatcct aagaagcaac tattcaagcc actaggttct ccgttgaaag
     1021 cacttgatga cgtatctcta gagttaagaa aaggaactac tattggtatc gtaggagagt
     1081 ctggaagcgg taagagtacg attgcgaaat cattaatgaa actccatgat attacagatg
     1141 gtgaaatcaa tattgatttg aatgggaaaa ctcaaaatat ttatggaatt aaacgtaagg
     1201 aagatttgga tttccgtaag aaagttcaaa tggtattcca agatccttat gcatcattga
     1261 acccaactaa gaaaatttat aattcatttg atgaaccgat gattgtccat aatattggaa
     1321 acaaagagga acgctttgaa cgtatgaaag aagccttgaa gatggtaaac gtgccagttg
     1381 agtacttgga gcgttatcct catgaatttt caggcggaca acgtcaacgt ttatgtattg
     1441 ctcgtgccct ttgtatgaaa ccagaaattt taattttaga tgaacctgtt tcagcattag
     1501 atctatctgt acaagcgcaa gttttgaatt atcttgttga aatccaaaat aaagaagatt
     1561 tgacttatgt atttatttct catgacctag gtgttgtgaa atacatgtgt gactatctat
     1621 atgttattca taaaggacgt attgtagaag ctggttctcg agaagatatc tacaataacc
     1681 caatgcatat ttacactaaa aaactattag ctgctattcc agaagttgat tatcacttca
     1741 aagaggcatt ggcaacaaaa cgtaaagaaa atgaagttga atttaaagca cagtaccatg
     1801 aattttatga tgaagatggc cgtgcttatg atcttaagca ggtttcacca acacattttg
     1861 tagcgttaaa accagaatag gtggtaaata tgaaattaaa taaaaaaata tatttctttg
     1921 ataaaggaat ttttaatcct tatcgaatga gtaatgtaaa attaaaagtt aatcaggcag
     1981 taaaggataa agaaattttc ttcactgagg aaaaaccatg ggaaattcgt tttgataaca
     2041 gttatccaaa tgttttcttt gatgatttag caggtgttta tcgttgctac tattctacat
     2101 ttactgatga tgaggagtct gaaaaatact ctttagagga gcgtaaggaa cgtcaatatc
     2161 tacctcgtgc gaagcgtatt gtttcacttt gttatgctga aagtaaagat ggtgttaact
     2221 gggtgaaacc aaatctaggt attacagaat ttcgaggatc aactgaaaat aatattatcg
     2281 gacatttttt acatggtaca tctgtttttc tagataaaca tgacgcagat gaaaatcgtc
     2341 gttataaaat gtttacaaag attgattacg gtaacggtgt tcatttcatt gctgtagcat
     2401 tttcaaaaga tggtctacac tttgatgaat acattaaagt accaaacttc aatccacgtg
     2461 cagacactca taaccatatc atatatgatg aagcattaaa tcgctatgtg ctaattactc
     2521 gtacttggag agattcattg cgcttgccgt gtgtatctac gagtgctgat ttcattaact
     2581 ggactccaat tcaagaaatt ttgaatgtct gtgattatga aaatcaaatt tattctatgc
     2641 ctatttttaa acgtggcgat tatatactag gtttagcttc agttttccat gaaggagatc
     2701 aactgaacaa gaattacgat acagtggacc ttcaattgac ttatagttat cgtcatgttg
     2761 gttggcatta tctaaacact gatactccac ttattcctcg tggtaaaggt caatatggtg
     2821 atggagaatt tgactgtgga tgtatctatt cttctgcacc agttactatc ggtgaccgta
     2881 cttatttcta ctacatggga ggaaatggac aacatacaaa cttccgtgaa acaagcttgt
     2941 ctcgtgctta tattgagaaa gatcactttg catattggga tactaaacgt ccagaatatc
     3001 caggtgtttt gtataccaat ggatttattt tcctcaatga tcaagtttac cttgatgcag
     3061 atattgcagc tggaggcttt gtaacaattg aattgttcga gaataatcac actccaatgg
     3121 aaattacagc ttcccttgaa aaaatagaag atggtcgcta tcaagtgtta ttcagcgaac
     3181 ctttacctcg aactcaaact cgactgaaaa ttagctttaa aaatgctaaa atctacgcaa
     3241 tcgaaggaaa tttagatatt ttcagaattg aatcagacaa tgctctattg agggggtaag
     3301 attatgaaat atgatttata tgataattgt attgaacttc taaaagaacg cgaagttaca
     3361 attgaagata tggcagcgtt agtaatattt tcacaacaaa aatattaccc tgaattaact
     3421 cttgacgacg cttcatatgc aattcaacgt gtactaaaaa aacgtgaagt tcagaatgta
     3481 attatgacag gaattgagtt agataagtta gctgaagcac aaaaactatc tccagaattt
     3541 caaaagatta tggagaaaga taatccattg tatgggattg atgaagtaat cgtcttatcg
     3601 atattgaatt tatatggttc tattgccttt acaaattatg gctatttaga taaattaaaa
     3661 ccactgattt tagaaagatt gaatgagaat cacgaaggtg tttgtaatgt atttctagat
     3721 gatattgttg gtgcaatagc cgcagcagca tgtagtaaaa ttgcacacaa tcatgctagt
     3781 gatgaaatat aactattgaa tttagtatcg taaataataa agcgtttggt ttctagatta
     3841 ttgtcattca aattggataa tgataaatct agaaaccaaa tatattttcc gcataaaatg
     3901 agggattata tatctcactt ttttacaatt gtatagtgga ttaaaactag aatagtgca
//
LOCUS       DAVHSI010000079         3896 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.084, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000079 DAVHSI010000000
VERSION     DAVHSI010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3896
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.084"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            204..1253
                     /locus_tag="VVR21_002060"
                     /pseudo
     CDS             204..1253
                     /locus_tag="VVR21_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1225..1869
                     /locus_tag="VVR21_002061"
     CDS             1225..1869
                     /locus_tag="VVR21_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU6055844.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSQEKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(1911..>3896)
                     /locus_tag="VVR21_002062"
     CDS             complement(1911..>3896)
                     /locus_tag="VVR21_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU6055845.1"
                     /translation="FRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNPK
                     IAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHLI
                     SMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLLV
                     FGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLALT
                     VKDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLIF
                     RMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDLD
                     KLLSQFASDKGYKIKEKEVLRYTYFAVTNQEGTKLTIFEKGQNRVQPKTVFMVFDQKD
                     YENMTGQKLSLSGNEVGLFVKNDGLKGQKTLTLNDHQFSVKEEFNKDFIVNHVPNKFN
                     ILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQFN
                     AQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGYE
                     DRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGVL
                     DTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
BASE COUNT         1246 a          763 c          782 g         1105 t
ORIGIN      
        1 attcgatttt actgtcctga tcgatttgtt ctgttcttgt ttcattttac tatatgttcg
       61 taaatgaaag ttctataatg aagttagcca cccagccctc ctaaaaatta gatggttcaa
      121 ctagctgaaa gctcttgtag gcataagaaa acacctctgt gttatacttg ttgttcaacc
      181 acaaacacaa gaaaggcaca gaaatgcaag acaattatac tacaaaaggt aaacatttga
      241 caatcgatag ccgtcgctta atcgaaagat ggaaaaaaga aggaaaatca aatagagaaa
      301 ttgcctctct acttggaaaa gctcctcaaa ctatccacac tgaaatcaag cgtaggacag
      361 tccgaaaatg tcttggaaaa gggcgcttca aagaggttta ttctgccgac tatgctcaac
      421 agtcttatga aaataatcgc aagcactcgg tcaagagatc aagcgtgacc aaggaactaa
      481 aggaaaagat tctccactat cataaccaaa aatttttgcc tgaaatgatg gttatggcta
      541 aaggggttaa cgtgggaatt tcaaccattt actattggat tcatcatgga aaattggggt
      601 taagcaagca ggatctgctt taccctagaa aaggaaaagc gcttaagaaa caggctagca
      661 ccaactttaa acctgctggt caatccatcg aacagcggcc tgaagctatc aatcttcgct
      721 tggagaatgg gcattatgag attgatacgg ttctacttac gagatcgaaa aactactgct
      781 tgcttgtctt gacggatcga aagagtagac atcagatcat ccgattgatt ccaaataaaa
      841 gtgctgaggt ggtcaatcag gctctaaaac tcatcttaaa acaacacaag attctttcca
      901 tcacggcaga taatggaacg gaattcaatc gcttgtttga tatattttct gaggagcaca
      961 tctattatgc gcacccctat gcctcttggg aaaggggaac taatgagaat cacaacaggc
     1021 tcattcgtag atagttacct aagggaacca agaaaatgac tcccaaagaa gtcgcattca
     1081 tcgaaaagtg gattaacaac tatcctaaaa aatgcttgga ctacaagtca cccagagaag
     1141 acttctggat ggctaacttg aacttgaaat ttagcgtcag aaacaaatca cgaaatcgat
     1201 tcaaattttg caggtcgttt aaatatccta cgcgcaggtg ttcttggtgc taacgatgga
     1261 attatttcca ttgctggtgt ggttatcggg gttgccagtg ccacgaccaa tatctggatt
     1321 atctttttat caggatttgc ggctatctta gctggtgcct tttcaatggc tggtggagaa
     1381 tatgtatccg tttcaactcc aaaagatacc gaggaagctg ccgtttcgca agaaaaactc
     1441 ttgttagacc aagataggga actagccaaa aaatccctct atgctgctta tatccaaaat
     1501 ggagaatgca aaacttctgc ccaactcttg accaataaga tctttcttaa aaatccactc
     1561 aaggctctgg tagaggaaaa atatgggatt gagtatgaag aatttaccaa tccttggcac
     1621 gctgccattt ctagcttcgt tgcctttttc cttagaagtt tgcctccaat gctgtcagtg
     1681 accatattcc caagtgaata tcgcatccct gctactgtcc ttattgtcgg tgtggccctt
     1741 cttctcactg gttacactag tgccagactt ggaaaggatc cgactagaac agctatgatt
     1801 cggaaccttg ctattggtct cttgaccatg ggagttacct tcctgctcga acaacttttc
     1861 agcatttaga atacaagaaa tacctcgatt ttgaagtcga ggtatctttt ttacatttgc
     1921 acaatcttgc gataacttct tgaagtaatc atgaaaatca gcacataggc gatgaggaag
     1981 atagcgcaga tagacaaggt cacaatcaac atcatagtcg tatccagtac accaatcact
     2041 tttaaaatca ggctaagcat atggtaggca aaggcgagat gtatgaaggc aaagagcaaa
     2101 ggaaggaaga aaacagttaa aacctgtttg ttgatggttt gcttgatttg cttttggtcc
     2161 aaaccgactt tctgcaagat aataaagcgt tcacggtctt cgtagccttc agaaatttgt
     2221 ttgtagtaga tgaccagaac agttccgacc ataaagataa tggataggaa aataccgata
     2281 aagaagacac caccaaagag ggcactcatc tgagaactag catctgctag attgctacca
     2341 taaacatagc taccttctgt gtctaattga gcattaaatt gattgaggta gttttcatac
     2401 tcctcagcga ccttgagttg ttcttcttcg ctggcatcta cattcatacc accgtaaaac
     2461 tgattataga tagccgaatc tgggaattga tccaaaaagg cttgtaaatc aggaacaaca
     2521 aggtaattgt aatcagtagt caagatatta aacttatttg gaacatggtt gacaatgaaa
     2581 tctttattaa attcttcttt gacagaaaat tgatgatcat ttagagttag agttttctgt
     2641 cctttcagtc cgtcattttt gacaaagaga ccgacctcat ttcctgatag agacagtttt
     2701 tgaccagtca tattttcata atctttttgg tcaaatacca tgaaaactgt ttttggttgg
     2761 acacggtttt gtcctttttc aaaaatagtt aacttggttc cttcttgatt cgtaacagca
     2821 aagtaagtgt aacgaagcac ttctttctct ttaatcttat aacctttgtc acttgcaaac
     2881 tggctcaaga gtttgtccaa atcttctttt tcaacatttt gccctgaaac cccaaaatca
     2941 tgaggattta gaactttttt aaaggattct gcggaattga aaatgcttgt cgctgctgac
     3001 atggttacca aaaccattgt tgacaaaata gcgatagttg ctagtccaac tgcatttttc
     3061 ttcatacgga aaatcaagtt agaaacagat atgagattat taggttggta atagtatttc
     3121 ttatttttct ttaagatttg aagaaaaacg gtaatccctg cattgaacaa aagataagta
     3181 ccaaagataa ccagtaaaac agctaggaag aaggttgtta aggctgtaag aggatctttt
     3241 accgtaaggg caagataata tccaatccct aaacttatgg aaccaagaat agtttggaga
     3301 ggaaggaagc gacctttttt ctctccgcta gctttctcac gtgagagctg gagggcattc
     3361 atacgggcga ttcgaagggc attcaggaac atgaggccta ggaaaatcaa accgaagaca
     3421 agaagtactg taatgacaac tttcatctgg aaggtagcga ccagttccac cttcaatttc
     3481 atcagtttga gtaggaaagc gaaaatcaac ttgtcaaaca aggctccaat accgattcct
     3541 gctccaacag ttagaatccc aaatagcact aactccttaa aggtcatact gattagatgg
     3601 cgcttctcca agcctaacat gccatatata cccagttcct tggaacggtt tttcatgaca
     3661 aaactattgg catagaggac gataatggct gacgcaaggg taacgacaaa cataccaaat
     3721 ccaagtgttg cttgaatggt ggttcctcca cgaatttccg caatcttggg attgaaggtt
     3781 agggagtaaa agagataggt gatggtgact gccaagagaa cagccagtgc aaagggatag
     3841 tagagtttgc ggtttttaat caagttcgat accgctaact tattggttaa tcgaaa
//
LOCUS       DAVHSI010000080         3595 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.086, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000080 DAVHSI010000000
VERSION     DAVHSI010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.086"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..1984
                     /locus_tag="VVR21_002063"
     CDS             <1..1984
                     /locus_tag="VVR21_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU6055846.1"
                     /translation="LFIQNYYFGYMTVLFLIFWYLCQISWDFKTRKSSVLDFIVISFL
                     AGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAKQFIGSFDTTKYGAIPM
                     IFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIEALDLFWQGMHTPNMFL
                     HRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFLATIYLKSHYSFLTDLN
                     ILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSLNASSQMDGIAKEWGFA
                     SRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNYNGISQFSSVRNRSSSS
                     TLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDKYGFKDIYQKDNLTLYE
                     NQYSLPIAVASQSVYNDVKLNEHTLDNQASFLNQLANVNFDYFSPIPYEKTEKIENTN
                     DLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVDILVNGEKKTFTTD
                     NVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFTEAIQKIKEQPVTV
                     STSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQTGFMKVDIPKGKGT
                     ITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2014..3595)
                     /locus_tag="VVR21_002064"
                     /pseudo
     CDS             complement(2014..3595)
                     /locus_tag="VVR21_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472064.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
BASE COUNT         1125 a          663 c          556 g         1251 t
ORIGIN      
        1 cttatttatt caaaattatt attttggata tatgacagta ttgtttctta ttttctggta
       61 tctctgtcaa atttcgtggg actttaagac tcgaaaatca tctgttcttg atttcatagt
      121 tatctccttt ttagctggta tggctagttt gattatgact cttcccactc tatttgattt
      181 acagacacat ggggaaaaat tgactgaagt tacaaagttt caaactgaaa gtagctggta
      241 tcttgatctc tttgctaagc aattcattgg ttcctttgac acaacaaagt atggggccat
      301 cccaatgatt tttgttggac tatttccctt tattttgacc attttatttt ttacgctgaa
      361 atctattaag tttcacgtga aactcatata tgtaatattc tttgcatttc taattgcaag
      421 cttttacata gaagctcttg acttattttg gcaaggcatg catactccaa acatgttttt
      481 acatcgctat gcttggattt tctctacctt gttaatttac acagcagcag aagtcttaaa
      541 gcgtctgaaa gaacttaaag tctggaattt tttagtttcg ctttttcttg tagtagcagg
      601 atttttagct accatctatc taaaatcgca ttattctttt ttaacagatt tgaatattct
      661 gcttactctt gaatttttgg ttgtctattc tcttttactc cttgcagtta tcaaaaagtt
      721 tatatctgtg aatctatttg ccattctaat ctctttattt atactggttg aaatgagttt
      781 aaatgcttca tctcaaatgg acggaattgc taaggaatgg ggatttgctt ctcgaagtgc
      841 ttatagtcga gatatcccag ctatggaatc tttctcaaca tatattggaa atcaatttac
      901 tcgtactgaa aaactacaaa ctcagacagg aaatgacagt atgaaattca actacaatgg
      961 aatctctcaa ttttcatctg ttcgaaatcg ttcatcaagc tctactttag ataaacttgg
     1021 ttttaaatcc tctgggacta atctcaatct ccgatatgca aataatagta ttttggctga
     1081 tagtttattt ggtatccagt acaatatctc agacagtcct attgataagt atggctttaa
     1141 agatatctat caaaaagata atcttaccct atatgaaaat caatactctc ttccgattgc
     1201 agttgctagt caatctgttt acaatgatgt caagttaaat gaacatacct tggataatca
     1261 ggcctcattt ttaaatcaac ttgctaacgt caattttgat tatttttctc caatacctta
     1321 tgaaaaaaca gaaaaaatag aaaatactaa tgatttgatt agtgtcacaa gttcttcaaa
     1381 tgaagatgca gcaatccagt atcaaattga agttccagaa aacagccaag tttatctctc
     1441 tttcataaac cttcactttt ctaacgataa acaaaagaag gttgacatcc ttgtaaatgg
     1501 tgaaaaaaag acttttacaa ctgataatgt cttctccttc tttaatctag gatatactaa
     1561 agagaaaaaa actttcaata tcaatgttag tttccctgga aattcacaag tatcatttga
     1621 atctcctacc ttctatcgtt tagataccaa aactttcacc gaggcaattc aaaaaattaa
     1681 agaacaacct gtcacagtat caacttctaa aaacaaggtt tttgctacat atgatgtcca
     1741 acaagataca tctattttct tcaccattcc ttatgacaaa ggttggtctg cctaccaaga
     1801 tggtaagaaa atagaaatta aacaagctca aactggattt atgaaagttg acattcccaa
     1861 ggggaaagga actattacac tttccttcat tcccaatggt tttattactg gagcaatctg
     1921 ttcctttact tctctcttac tatttggaat ctataatcac agacgaaagt catctaaggc
     1981 ataaaaaatc gaccagttaa tcggtcgatt tttttaatct tcttccattt tcttatgttg
     2041 ataggctagc atacctaaac cagtaaatag agctagtatg acagctagga aaatgacttg
     2101 ttgatagaga ttgtttgtcg taatcccgaa actgaatagc tcattggtaa ccagggatta
     2161 atagatctaa agaaatcatt tgtcaaagca agtggataag tacctgcact tgatgctaac
     2221 tgtagtaaaa gcaaaataag tgagaaaaaa gctcctatac ggctattcca cgttgctaaa
     2281 gtggtcacca tagacatgaa tactaaactt gttaggatga tgagaataaa tattctcatc
     2341 tcatgattag cagttaaacc aataagctga actcctccat ataccaaaat tcctgccaaa
     2401 acagctataa taccatttat ttcagctcaa gatttcaacc aagcccaacg gctctctgga
     2461 tgacgtcctg aaggcaattt cgcaaatatc atatttgttg atattgctgc aaaaaaaaga
     2521 gcaactgata tcatataagg agctattgcg attccattta caggaacttg atcattgtct
     2581 gtttttgaaa gattgagtgg atttgacaaa atctctgcat ttttagattc tgttgatact
     2641 gatttgagtt gatcactagc attacctagt ccttgtccta aagaagcaag tcctgtctgt
     2701 aaatcttcca atccagaagt taactttgtt ccaccttctg ctagtttcct agatccatct
     2761 gccaatttat tagctctatt ctctaatgga gaagcacctg aaagtaactg actggatttg
     2821 tctgctaatt gcccagatcc tgattgtaat taaccaactc ctgctgtcaa tctagaagat
     2881 ttttgtgtca aggtgtttga gcctgaaact agtttatcca aactacctgt caaggtggca
     2941 tttttttcac ttagttgact tgcgccctga gaaactttat caacacctgt agtatatgcg
     3001 tttacacctg atgcaatcga ctgactggca ggaactaatt tgctagtaac atctccttgt
     3061 atctctgtta atccacttga caatcctatc aaagaagtag aagtaatagg tgatacttga
     3121 ttagattgat tttttaaagt cgaaagatta gaagattgat tttgtaagtt ttctaaactt
     3181 ccctgtaaat cttgtactaa agctacaatt gactgagccg attgaatact atcagttgaa
     3241 ttttgagata cagaatcact tatctcagtt tgttgctcac ttgtcaatga ttgataagct
     3301 gctgtcgatt gaatattgga taatgtagtt gttttttcag ataaatcact tggtaaagtc
     3361 actaccatat agtaatcgcc atcttccaat cccttctttc cttcctcttc atctacaaaa
     3421 tgaaaatcca aggttttatt ttcttttaaa ttggacacca tgtctttttc tattgccata
     3481 gtattaccat tataggaagc ctctttatca ttatttacaa ctgccacagg taagtcagac
     3541 aattgcccat atggatccca cattgatgac aaaaatatga tattgtacag atctg
//
LOCUS       DAVHSI010000081         3530 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.087, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000081 DAVHSI010000000
VERSION     DAVHSI010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.087"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(34..489)
                     /locus_tag="VVR21_002065"
     CDS             complement(34..489)
                     /locus_tag="VVR21_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055847.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKNQQGNTMESYF"
     gene            complement(764..2503)
                     /locus_tag="VVR21_002066"
     CDS             complement(764..2503)
                     /locus_tag="VVR21_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU6055848.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFAHIQYLFEIIDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAIMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            complement(2666..3529)
                     /locus_tag="VVR21_002067"
     CDS             complement(2666..3529)
                     /locus_tag="VVR21_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU6055849.1"
                     /translation="MNPTSGGEKALDYKEKLENKAKEYFEYVETKITEKALDATHFAE
                     EASRERYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKFLEINQDIDD
                     AIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILTYAVNTMK
                     SVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASI
                     FSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQ
                     RVEVFSKPKED"
BASE COUNT         1067 a          745 c          533 g         1185 t
ORIGIN      
        1 atattttata gaatacccaa aattcaacaa taactaaaag taagattcca ttgtatttcc
       61 ttgttggttt ttcatatcac gaattttatt tttcagaata ttaaagttac aaatttcatc
      121 tctaatatcg ttatccgctc tgtagccatt aatcatctca gtcagagttt tccctttact
      181 accattcttt atagtagtat ttactctttt tatactgctt tcaaaaggct catatgtttt
      241 atacttaatt acttcgtctt taaaattaaa taaaggtgta tccggcttag cattccataa
      301 aataatcaac cacattatag cattataaag ctgctttgca gtttcattcc acttttcagg
      361 ttgtaaattt ccactccctg tattgtcata ttcttgtcta ttatttacat gagaatcacc
      421 tacaagcgga ttaaaaagag gtagcccttt gtgattaatt agttctaaaa aatcccttgc
      481 cgcacccatg caacactgaa taacttcctt cttgccatca attttactct cagcgataaa
      541 tacataatat tcatcttcaa tagttgctcc tgcatcacta tgtttttgtt gatttgctaa
      601 cagcttaata tgtgctttag gctaaacttc aaaatctcta acaattcttt gtcttgtttc
      661 atgtcctcta caattcattt aagttctcct ttacaagttt agtaactagc cttattatac
      721 tatataagat atgaaatgta ccataatctt catcaactag tttttagaaa atcacaaatc
      781 catctggaga gatgacaagc tgattctcca attcttggca attgcttgct agtgctactg
      841 cttctttctc taaaagataa tcttctgttg attggttgaa tattgctttg aggatccgtc
      901 cttcgtattt ccattccaga gctactaaat cagatttgat ttcttgaagg ctatacttgc
      961 catgcgaaat aattactgac gcgtatttcc gaatcttaat cagcctcttc ataaagttca
     1021 gcatatcatt gtcacttgat acacgttccc aaggcataca acgacgacaa tctggatctg
     1081 gtcctccagt caaggctagc tcggttccgt aataaatgca cggtgttcct ttttgtaaaa
     1141 agagaaaggc taaggctgat ttaaccagtt gaacatcttc attggccgtc cacaggattc
     1201 gctctgtatc atgtgaatcc aagagattaa acatgacctc tgaaatctgc tgcttgtaat
     1261 acatagactc tccattgatt tcatcgatga actggtctgt cttcttaatt cctcgtaaga
     1321 aatagtcctt gatactatca gataaaggat aattcatgat ggcatggaac tcatctccat
     1381 ttagccaagg ctgagatgta tgccagactt ctcctaggat ataaagatca ggatttttag
     1441 ctaaaactgc cttacgaaaa tccttccaga actgatggtc aatctcatta gccacatcca
     1501 aacgccaagc atcgatatta aactcttcaa tccaataagt cgcaaccttt aaaagataat
     1561 tcttgacctc tggattggct gtatttagct taggcatata gtcctcgaaa ccaaaaacat
     1621 gatagggtaa gtctctctta ttaactagct tttcagttgt cactgggaat tgttgaatat
     1681 ggaaccaatc cttataagca gactgttcac catttttgac gacatttttc cattgaagag
     1741 attgcgaacc aatatgatta aataccgcat ccagcatgac tttcatgcca cgatgatgcg
     1801 cttgatccac cagttcccga aaggtctcct tgtctccaaa atgacggtca atttcaaagt
     1861 aatctgtcgt attgtacttg tgattgcttg tagattcaaa gatgggacaa agatatagtc
     1921 cagtaatacc caagtcttgc aagtaatcca tatgatcaat aatcccctgt aaatcaccac
     1981 caaagaaatc atcgctctta ggtgtgacag atgaatccca gtctaaagtc ccttctgggt
     2041 ttaatagagc attgccattg gcaaatcttt caggaaatat ctgataccat accgtatttg
     2101 aaacccagtc aggaaccttg caggcatcaa tctcatgaag ataaggcaac ttaaatccat
     2161 tcccaattgc atgaagattt tctagagaat tttccacaca ccctttatcg ccatacaaaa
     2221 tattttgacc ttctgtatct atgatctcaa agagatactg gatatgtgca aagtcaactg
     2281 acacttcaac ctgccaatgg tcaaataagg taccagaagt tatcttgacc atttcttttg
     2341 tatcctgata aaactcctcc ataaagataa aagggtcccc atagtgcaag ttgatgcttt
     2401 caatgtcccc tttcttagtt cgaattcgaa tatggagttt cttatcctta taaagatagg
     2461 catactccga ctcaggccta tggtaaatag cactcaattc catcaatttg tctcctaaag
     2521 tattcattca aattttacgc aaacgttttc aaactcaata aatccagtat actatttttg
     2581 taaactattt gcaaggaatg tccgttgtta aaggaactat cttttaaagt atacaaaaag
     2641 ccttaaaaaa ggctttctct atatactaat cctctttcgg ttttgaaaat acttctactc
     2701 gctgagctag gactttgatt tctacaggta ggttatctga tttatctccg tcaacatctg
     2761 actccaattc actatctgaa gagattttaa tattacgcgc tttgatatac tcgatattat
     2821 catttgcgac aacatcccct tttaataaat caggaatgac ggataatttg gagaatatag
     2881 aggcatcttt cagaatcaaa atgttggcat agccgtcctt gttttcttca aagattttct
     2941 tatcagcgaa gtaatttgtc aaaagaacca aaacatggct agcttcacca acataatttc
     3001 cattttctgt ctcaacctta atgttaaaga cctgatctgt catgacagac ttcatggtat
     3061 ttacagcata ggttaaaata ccgaattttg ttttgtcctc tatttcaaca ttgtgaatcg
     3121 cctcaggcag agaaccgata ctaaagatat aaccaaaata gttgtcattt gctttaccga
     3181 tatcaatctt attggttaaa tcaaaatcca gttcgtcaat tgcgtcatcg atgtcttgat
     3241 tgatttccaa aaattttgta atgaggttac ccgtaccgcc tgggataatc cctaacttag
     3301 gaatgtagtc tctctcatca atacctgaaa tgacttcatt gacagttcca tctccaccaa
     3361 acacaaccac tgcatcatac cgctcacgag aagcttcttc agcaaaatgt gttgcatcca
     3421 gcgctttttc ggtaattttg gtttcaacat attcaaagta ttcttttgct ttattctcca
     3481 gcttttcttt gtaatccaaa gccttctcgc caccagaagt agggttgata
//
LOCUS       DAVHSI010000082         3347 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.088, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000082 DAVHSI010000000
VERSION     DAVHSI010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.088"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..110)
                     /locus_tag="VVR21_002068"
     CDS             complement(<1..110)
                     /locus_tag="VVR21_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU6055850.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYG"
     gene            complement(295..906)
                     /gene="rpsD"
                     /locus_tag="VVR21_002069"
     CDS             complement(295..906)
                     /gene="rpsD"
                     /locus_tag="VVR21_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU6055851.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1101..2153)
                     /locus_tag="VVR21_002070"
     CDS             complement(1101..2153)
                     /locus_tag="VVR21_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU6055852.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2150..2848)
                     /locus_tag="VVR21_002071"
     CDS             complement(2150..2848)
                     /locus_tag="VVR21_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055853.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLLPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3015..>3347)
                     /locus_tag="VVR21_002072"
     CDS             complement(3015..>3347)
                     /locus_tag="VVR21_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU6055854.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT          943 a          749 c          637 g         1018 t
ORIGIN      
        1 ccataaatgg tattacgtga gatttggaaa acgtgtgatg cttctgttat actacctgtt
       61 cgctcacaat aagagagaac ttttttacga aaatctattg aatatgccat aaaagattat
      121 accacattgt gtactatttt tggttcattt tactatatca ctttggacta tatcggtcta
      181 gttatgtctc aacgattata gctggatact aagagaaatc aaaaaagcac taagggagaa
      241 cgtcccaaag tgcttaatat caaggcctca aagcctgtct tattcaataa aatattacaa
      301 catcttgttg tagaattcaa cgacaagtgc ttcgttgatt tctgggttga tttcgtcgcg
      361 ttctggcaag cgagtcaatg aaccttccaa cttttcagcg tcgaatgata cgaatgctgg
      421 acgtccaaga gtagcttcta ctgcttcaag gattgctgga actttcaatg atttttcacg
      481 aactgagatc acttgacctg gagttacgcg gtatgatggg atatcaacgc gtttcccgtc
      541 aacaaggatg tgaccgtggt ttacgaattg acgagcttga cgacgagtag tcgcgagacc
      601 aagacggtaa acaacattat ccaaacgacg ttccaaaaga agcataaagt tgaaacctag
      661 gattccacct ttgatttttg tagcttgtac gaacaagtta cggaattgtt tttcacctac
      721 accgtaagtg aaacgaagtt tttgtttttc agccaattgc aaaccatatt ctgacaattt
      781 agaacggttg tttggtccgt gttgtcctgg tacgtagtta cgacgtgcca attctttacc
      841 tgtacctgta agtgaaaggc caaggcgacg agcttgtttc caagatggtc ctgtataacg
      901 tgacatatga atgtcctcct gatataaata atatttcggt ggaaatagtc acttagaaag
      961 ccctgattcg tgcagatgcc cttcgcctaa acagccaagg ttacttgtca taagacacct
     1021 gttgacgagc ttcatgcttt cctgctgata tttcacacaa aatccatttt accatgaata
     1081 gctggatttg taaaggagtt ttaggcttta ttttcactac cagagagatt gagaacgagg
     1141 gtaaaggtac ttcctagacc gtactggctg ctgactgtga tttccccacc caattgatgg
     1201 gccaattcac gcgcaatcgc aagtcctaat ccatggccac ctgtcttcat gttacgcgaa
     1261 gtttcgacac gataaaggcg tttgaaaata ttttccaaat cctctggggc aatgccctgc
     1321 ccttcatcgg tcacactgat tgaaagctgg cccttctcca gcttagtcac cacttccagc
     1381 ttggttcctg gagcagaata tttaaaagcg ttatcgacca gattcaccaa gatacgagaa
     1441 agcttagcat aatctccctc aatccgggca gactctggga ttacttgcaa gtggacatct
     1501 cttctctcct gctcaatcaa aaactgaaat tcactcatgc actcaattaa gagcttgtcc
     1561 agaaaaatac tgtctttact ggtagtttcc acctgatttc tagctgtatt tagggtcaaa
     1621 aaattcaact cctcaaccag tttattgagc ctctccgtct ggcgtccaat ggttgctaga
     1681 taatgagctt gctccgactc cttgataatc ccatccaaaa tcccttctac cgtcgcttga
     1741 atcgaagtga taggggtctt aatatcatgc gacaactggg caatcatcaa gcccttttct
     1801 cgttcgcttt cttccaagga atcaaagctt acctgcaaat catgggacat ctcattaaaa
     1861 gtttgcccta attgctgaaa ttctacagga ccttgaacct ccaaatttga aggaaaatcc
     1921 ttggccgcta cccgcttggc atgctccttg agtttgccca acgacgtaaa gactggcaat
     1981 aggagaaaga gactaatccc agcaccgaca aggctggcaa cgatggtcat cccaagcaaa
     2041 aagtaaatct cgcctttcgc aatcagcatt ttttgaacag cccaaaaaac aaccaaaatg
     2101 gttaagaggg ttgaaataat atatccaacc aaaatataac tttttagttt catgtttgtc
     2161 ctctcggttt ctctatctta tatcccaacc cccaaactgt cttaatagtg ggcgtttggt
     2221 cactactata ttttgccagc tcctgtcgaa gagcatggat atgcacattc aaggtattgg
     2281 tgtcatccac gtagtcttct ttccagatct tttcatagag gtctgtcttg gagaaaactc
     2341 gctctggatt gctagctaaa atccacagca attcaaatga tttaacagtt aaatccagca
     2401 tttcttctcc tatttgaact tcatgactac tatgattcat ttttagattg ccaagggaaa
     2461 tcagctctgt ttcgccccca cgatgaaggc ggcgcaaaat attgtggaca cgcaaaacta
     2521 gctcacgtgg gctaaaaggc ttagcaataa aatcatctgc tcccaagctc aggccgtaaa
     2581 tcttgtcctg ttcactggtc ttagcagtaa taaataggaa aggctgctct ggtaataagt
     2641 attgaacctc actgattaaa tcataaccat ccatccgagg catcatgaca tctgtgataa
     2701 tcaaatcaat cggttttttc ttgaacagct ctagcgcttc cagtccatca tgggctacca
     2761 agacctgata acctgcctga attaagtatc tctgatgaat atctgtgatt tctacctcgt
     2821 cgtcaacgag taaaattgtc tttcccatct gtctctcctt tgataaaaac agtgctatac
     2881 tgctttaagt ataacactat ttttattgtt ttacgatgat tttaatctgc tattgaaaga
     2941 aagtcctgat tgctgattga gttgttaaac taatcttagt cagcccacta tccatcattt
     3001 atttccttag ctgattagtt ttcttctttt ttgtttttca aacctagacc accgagtaaa
     3061 cctgcaagcg caagcccaag gaaaccaata cttgccattg atgtttgagt ctcaccagta
     3121 tttggtagca tagctttatc ctctgacatc atcgtatcag acatcttgtt agcagaagca
     3181 gccatgtttt cacctgccat cgtgttggta gaacttgtca tggtgtcagc aggcatgcta
     3241 tctgtagtac ctgtagcatg attgtgattc atcggagtca cgccagaacc agagttagaa
     3301 ggtgataatg aaccatttgc tgtgtctgat gtttctttaa catttat
//
LOCUS       DAVHSI010000083         2894 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.092, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000083 DAVHSI010000000
VERSION     DAVHSI010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.092"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            55..1305
                     /locus_tag="VVR21_002073"
     CDS             55..1305
                     /locus_tag="VVR21_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU6055855.1"
                     /translation="MKAIREGFMMAMPLILVGSLFLILISWPQEDFTNWLNSVGLLSI
                     LTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPSAGIIALSSFVLMAPRFSSMVYDKN
                     GEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAEIYRMFIQRGITIKMPSGVPDVVSK
                     SFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGLLGAIVGTPLKLIAGTLPGMILCVI
                     VNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEAVAAGQTLQHIITLPFKDLFVFIGG
                     GGATIGLAICLFLFSKSRANKTLGKLAIIPSIFNINTAILFTFPTVLNPIMLIPFIAT
                     PTINALITYVSMAVGLVPYTTGVILPWTMPPIIGGFLATGASWRGALLQVVLILVSVA
                     IYYPFFKIADKRNLEKEKATVGGK"
     gene            1307..>2894
                     /locus_tag="VVR21_002074"
     CDS             1307..>2894
                     /locus_tag="VVR21_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU6055856.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGHRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLA"
BASE COUNT          858 a          444 c          626 g          966 t
ORIGIN      
        1 tttttagaaa caaaagtcgc tccgtttggt gaaaaagttg gcaaccaacg gcatttgaaa
       61 gctattcgtg aaggatttat gatggcaatg cctttgattt tagtcggctc tttatttctt
      121 attctaatca gttggcctca agaggatttt acaaattggc tgaatagtgt tggattgcta
      181 agtatcttga caactatgaa tcagtcaaca gtagcgatta tctccttggt cgcttgtttc
      241 ggtattgcct acaggttgtc ggaaggatat ggtacagatg gtccgtcggc agggatcata
      301 gccttatcca gttttgtatt gatggcacct cgtttttcga gtatggttta tgataaaaat
      361 ggggagcagg tcaagcagtt atttggcggc gcaataccat tttctagcct gaatgcatct
      421 tctttgttta tggcgattac tattggattg gttacagcag agatttatcg tatgtttatc
      481 cagcgcggaa ttacgataaa aatgccaagt ggtgtcccag atgtggtaag taaatcattt
      541 tcagctcttt tacctggctt tactactttt gttttgtggg ctctggtctt aaaaggtctt
      601 gaagcggcag gagttgcagg aggtctcaac ggactcctag gtgcaattgt tggaacaccg
      661 cttaagttaa ttgcaggaac gcttccaggt atgattctat gtgttattgt aaactcattc
      721 ttttggttct gtggagttaa tgggggacaa gttttaaatg cttttgtaga tccagtttgg
      781 ttacaattta ctacagaaaa ccaagaagct gtggctgcag gacaaacact ccaacacatt
      841 attacattac cgtttaaaga tttatttgta tttattggtg gcggtggagc gactattggt
      901 cttgcgattt gtctcttcct atttagtaag agtcgtgcga ataaaacatt aggtaagcta
      961 gctattatac cgtctatttt taatatcaat acagctattc tatttacgtt tccaacagtt
     1021 ttaaatccga ttatgctgat tccgtttatt gctactccta caatcaatgc cttaattacc
     1081 tatgtatcaa tggctgtagg attagtaccc tatacaacag gtgtaatcct tccgtggaca
     1141 atgccaccga tcataggagg cttccttgcg acaggagcta gttggcgagg agctctatta
     1201 caagttgttt tgattttggt ttctgtagca atttattatc cattcttcaa aattgcagat
     1261 aaacgcaatc ttgaaaaaga aaaagctact gttggaggga aataagatgg ttatcagagt
     1321 atttgataag cagaaaaata cttattctag ctttgcctta gaggaattaa gttactatat
     1381 aaatcgggtc tttaagactg acatagaact tgtcgaggag aaggaagcgg atatttttgt
     1441 aggattagtc aataaagagg atagaagaga ccatgttctt atctcattag acaagggtaa
     1501 ggggagaatt gagtctaata caattgtagg tttacttatt ggaatttacc gaatgtttca
     1561 tgaatttggg gttgtgtata ctagaccagg gcacagacat gactttgttc cagagttacg
     1621 atttgaagat tttttagata aacagctatc tatagatgaa acagccagtt actatcatag
     1681 gggagtatgt atagagggag cggattcatt tgaaaatata ctagatttca ttgattggct
     1741 acctaagatt gggatgaaca gttttttcat ccagtttgaa aatccctact cttttttgaa
     1801 acgttggtat gaacatgagt ttaatccata cctaaataaa gaaaaattct caaatgaatt
     1861 agtacaagaa ttgagtgata ggttggataa agaattgcaa aaaagaggtc ttattcatca
     1921 tcgtgttggt catggatgga caggtgaggt tttaggttac tcttcaaaat ttggctggga
     1981 atcaggtctt agtatttcag aggagaagaa accgtatgtc gctgaaataa acgggaaacg
     2041 agaattattt aatacggctc cgattttaac cagtctggat ttttcaaatc cagatgtggc
     2101 ggataagatg gtagaaatta tcaaggatta tgccaagaaa agacctgatg ttaactactt
     2161 acatgtatgg ttgtcggatg ctcgtaataa tatttgtgaa tgcgaaaact gtagacaaga
     2221 attggtttcg gatcagtata ttcgtattct caatcaattg gatagggctt taacgagtga
     2281 gggattagat acaaagattt gttttctgct ttaccatgag ttgctatggg cgcctcagaa
     2341 agaaaaatta gataatcctg aacgctttac catgatgttt gcaccgatta caagaacatt
     2401 tgaaatgagt tatgcagatg tagattttga caattccata cctacgccta aaccttatct
     2461 gcgtaataaa attatacttc cgaattctct tgaggaaaat ttatcttatc tttttgagtg
     2521 gcaaaaaaca tttaaaggag atagtttcgt atatgactat cctttagggc gtgctcatta
     2581 tggcgattta ggctatatga aaattagtca aaccatttac agagatgtat cttatctttc
     2641 taacctacat ttgaacggtt acatttcgtg tcaagaatta cgtgccggat tccctcataa
     2701 ttttcctaat tatgttatgg gggaaatgct ctggaagaag acaagaagtt atgaagaatt
     2761 gattgaagaa tacttttctg ctttgtatgg gtcaaattgg cagtctgttg ttgaatattt
     2821 agaaaaatta tccagttatt cctcatgtga ttattttaat gcaattggca gtcgtcaaaa
     2881 tgatgtttta gcga
//
LOCUS       DAVHSI010000084         2846 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.093, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000084 DAVHSI010000000
VERSION     DAVHSI010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.093"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..314
                     /locus_tag="VVR21_002075"
     CDS             <1..314
                     /locus_tag="VVR21_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055857.1"
                     /translation="KKGQFDELVSNLNLSEQEQLDLLQQYKEEHPRRAKRGIKSAIIK
                     KVARFLAAKVGQKSVVEITDYLFEWQDNLEVGAENYLVQYGWDRNIAHWTIKTVSFIF
                     L"
     gene            801..1763
                     /locus_tag="VVR21_002076"
     CDS             801..1763
                     /locus_tag="VVR21_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEU6055858.1"
                     /translation="MEKWENQDKILLDKNKRGKDRNWRGRKLLSLKLADIFKELGYRE
                     TLIERVETCGDTLRFIRREDGSLRLYQAYFCKNKLCPMCNWRRSMKYSYQTSQIVDEA
                     IKEQPKGRFLFLTLTVKNVPGKELNATISQLTQSFDRLFRRAKVKKNLIGFLRSVEVT
                     HNQEEETYHPHIHVLMMVKSSYFSGAGDNYVSQEEWGRMWEQSLKVDYVPMVDIRSVK
                     EIGKGLKGAILETAKYPIKPIKLDVENKQVVGDLYNGLYRKRQLGYGGLFKEIRKRLQ
                     LSNVENGDLVYTSDDNDEMSKGTKIVAIWNATKQNYFVKNKGWN"
     gene            2684..>2846
                     /locus_tag="VVR21_002077"
     CDS             2684..>2846
                     /locus_tag="VVR21_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055859.1"
                     /translation="MNKKFLKCGTLFLISCSILGSTIPAVTVFSDEVTITYNSENNSE
                     KNELYNQLSA"
BASE COUNT          988 a          335 c          593 g          930 t
ORIGIN      
        1 aaaaaaaagg acagtttgat gagttggtaa gtaatttgaa tttgagcgaa caagaacaat
       61 tagacttgtt gcagcagtat aaagaggaac atcctcggcg agctaaaagg gggataaaat
      121 cagctataat aaaaaaagtc gctcgtttcc ttgctgctaa agtaggacaa aaaagtgtag
      181 tggagataac tgactattta tttgaatggc aagacaattt agaagttgga gcggagaatt
      241 atcttgtaca atatggttgg gatagaaata ttgctcactg gacaataaag acagttagct
      301 ttattttctt ataagtcatt atgaataaag cttggttatt ttggagtgtc atagtcttat
      361 atttttttat aaagtttttt gataaagttt tagatataaa gctttttggt tctattcaaa
      421 tatggctaga taatctccct attccgatga aaatactgtt aacaatagca ttagttttgt
      481 ttttattcat tgtatttcca tatagaggaa aacggtaaaa acggtaatta gatatataaa
      541 aggagctgaa agctccgtaa aaaacctact cgaagagtag gttttttctt atcttgatac
      601 tagtaggaaa taactctcat gctattttta gggtttcgac agggtctaaa cccttgatac
      661 tactgacttt ttaggtaaaa aaatgccctt gacttttttc aacggatctt ttataattta
      721 gttgttcaga aaaaattata aaaagagaaa aaaggcaaag gtatttttgt atttctttgt
      781 aattacaggt aaattataac atggagaagt gggaaaatca agataaaatt cttttagata
      841 aaaataaaag aggcaaggat agaaactggc gaggacgaaa attattaagt ttgaaattgg
      901 cagatatttt taaagagtta ggttataggg aaaccttgat agaacgcgtt gagacttgtg
      961 gagatactct tcgatttatt cgtcgagaag atgggagttt gcgtttatat caagcctatt
     1021 tttgtaagaa taaattgtgt cctatgtgta attggagacg gtcaatgaaa tattcttatc
     1081 aaacatctca gatagttgat gaagcaatta aagaacaacc aaaagggcgt tttcttttct
     1141 tgactttgac tgtgaaaaat gttccaggta aagaattgaa cgcgacaatt agccagctaa
     1201 ctcagtcctt tgaccgtctt tttagacggg caaaggtaaa gaaaaatcta atcgggtttt
     1261 tacgttcggt tgaggtgact cataatcaag aagaagagac ctatcaccct catatccatg
     1321 ttttgatgat ggttaagtct agctatttta gtggggctgg agataattat gtatctcaag
     1381 aagaatgggg gcggatgtgg gaacagtcgc ttaaggttga ctatgtgcca atggttgata
     1441 ttcggtcagt taaagaaata ggaaaaggtc ttaaaggggc aattcttgaa acggcaaaat
     1501 atccaattaa gccgattaag ttagatgttg aaaacaagca agttgttggt gatttgtata
     1561 atgggttata tcgtaaacgg caattgggtt acggtggatt gtttaaagaa attcggaaga
     1621 gattgcaact gtctaatgtc gaaaatggag atctggttta tacttctgat gacaatgatg
     1681 aaatgtcaaa aggtacaaaa atagtcgcga tttggaatgc gactaaacaa aactattttg
     1741 taaaaaataa gggttggaat taaagtatca actcttttat tataacataa aaaagagtaa
     1801 aatagacttg atttttttga gtttagatgt atattgaagg tgtgaaaatt aaaaagatag
     1861 ctatgttttt tctgggtata cttgttgggg tatttattgt tctatttttt agaaattatt
     1921 ttgttttact tttggaatat atttttggtt aaaaagcacc ctctaaaaag ggtgcttttt
     1981 gtgcggttat tcgcacgaaa gttctctgca agagttcctc ggaagagcgt ttgtattttg
     2041 attgtacgtc aaaactataa aaacatttac tctttgtcaa aacgagtata aagagattat
     2101 ggaaaatgtt aatcaagcaa aagaggaatt aaagagaata gatgaattaa tagccgtcag
     2161 gagctccaga attgattttt tagaggataa aacccttaga attacaggga accaaagatg
     2221 agcttaaaaa cgaaatggag agcctaaaaa gagatttatc tttttttaga aacgaaaata
     2281 ctcgactgaa aaatgtagtt tcagattgta tcaaggtagt atttttgggg tatttttagt
     2341 agaaagtata ttgtaatttc tgagcgattt atgccgtgaa agctacttga ccgtaagcta
     2401 gatcaaagta cgctagtcag ggacgagccg aaaggctgta gcgtttcgga gcggcacgga
     2461 caaagtacgt cgacctaggt tacttgcggt caagtagacc atggaataaa acaagcgggt
     2521 atgatataaa aaagttatcg gcaaaccgaa atatagactt gtttttttgt ttataaaaat
     2581 gtattattat attgagaata agattgttta atttatttag agaggagtgt aagttgatca
     2641 gtaaacgatt ttaattctgc ctttaaataa caaggagttt gttatgaata aaaaattttt
     2701 gaaatgtggt actttatttt tgatttcttg ttctatttta ggaagtacta ttcctgcagt
     2761 tacagtattt tctgatgaag taacaattac ttataattca gagaataatt cagaaaaaaa
     2821 tgaattatat aatcaacttt ctgctg
//
LOCUS       DAVHSI010000085         2714 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.094, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000085 DAVHSI010000000
VERSION     DAVHSI010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.094"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..540
                     /locus_tag="VVR21_002078"
     CDS             <1..540
                     /locus_tag="VVR21_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU6055860.1"
                     /translation="QESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRSS
                     FYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSEN
                     GTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHGK
                     KESSQEITDFLMKMLGDTN"
     gene            complement(581..654)
                     /locus_tag="VVR21_002079"
     tRNA            complement(581..654)
                     /locus_tag="VVR21_002079"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(618..620),aa:Asn,seq:gtt)
     gene            complement(660..731)
                     /locus_tag="VVR21_002080"
     tRNA            complement(660..731)
                     /locus_tag="VVR21_002080"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(696..698),aa:Glu,seq:ttc)
     gene            complement(783..1535)
                     /locus_tag="VVR21_002081"
     CDS             complement(783..1535)
                     /locus_tag="VVR21_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU6055861.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(1532..2473)
                     /locus_tag="VVR21_002082"
                     /pseudo
     CDS             complement(1532..2473)
                     /locus_tag="VVR21_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285140.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
BASE COUNT          929 a          509 c          398 g          878 t
ORIGIN      
        1 caagaaagta acaaacgctt aaaaacaaag cgaactattg aaaatgctat ggtacaatta
       61 ctgatggaac agccatttga taaaatttct actgtcaaat tagtagaaaa agccggaatt
      121 agtcgttcca gcttctatac tcactataag gataagtatg atatgattga gcactatcaa
      181 agcaagctat tccatacatt tgaatatatt tttcaaaaac atgctcatca caaaagagac
      241 gctattttag aagtttttga atatctagag tcagaaccac ttctggctgc ccttctttct
      301 gaaaatggga ctaaagaaat ccaaaatttc ttacgaaata aacttcatat catgcttagt
      361 acagatttac aaaagcgatt tatgcaactg aatctaaata ccaccgaatt agaatatagt
      421 agcatctatc taactcatgc actttttggt gtctgccaaa cttggattgc acatggaaaa
      481 aaagaaagtt ctcaagaaat aacagacttc cttatgaaaa tgcttggtga tacaaattga
      541 tacaaaaaga ggaacacagc tgtgttccct tttatctata ctccgccagt aggactcgaa
      601 cctacgacat catgattaac agtcatgcgc tactaccaac tgagctatgg cggataaaat
      661 agtccgtacg ggattcgaac ccgtgttacc gccgtgaaaa ggcggtgtct taaccccttg
      721 accaacggac cttctatctg tagcagatat aaccattata tcaatttctt gctaattgtc
      781 aatcactttt gagatttttt ctctaaaata tcttttaatt ttctaatttt taatcttgaa
      841 ataggacaac gatggtcttc atagaaaaca atttctaagt tttttcgatc aatttctctg
      901 atattgccta tatttaccaa aaatgacttg tgaggagaat aaaatcgctg agtatgtttg
      961 tccttttcct gaatatctgt catggtacca taaaactctt ttgcaaaatt cttaccaata
     1021 atgcgcaatt tatgagatac ccctgttgtt tcaatataca aaatatcatg gtaaggaatt
     1081 tttaaatcat ttcccttgta attgtagtcg aaataatcta caacatcttc attttcaagt
     1141 aacatactct tcgtgtagaa gatattttgc tcaattctct tcttaaacat ctcatcattg
     1201 atatccttat caacaaaatc tagggctgat acctggtatt tataggttag agtcgcaaac
     1261 tctgatcgac tagtgataaa gacgataata gcgtaaggat tgtaatgacg aatgagctga
     1321 gccacttcaa atcccttttt ctcaattcca tgaatatcga tatctaggaa ataaagttga
     1381 tttacttcat cattttcaat gtattcttca aattcacgga cttttcccgt tgtcttgtat
     1441 gatattggaa tattcgattc tttcgaaatt tcatccaata ttctctctag tctcacttga
     1501 tgttcaataa catcttctaa aattaaaact ttcattcaaa ttccctctta aatctaatga
     1561 tttgtctaaa tgtactgcct tccatctctg tttctaaaat aatattgttg tacttatcta
     1621 gtagttcttt cacattattt aatcagactc cgcgatttct tcccttagtg gagaatccta
     1681 aggcaaatag atctcctgaa ggagtcatcg tcattttaca tgaattctga atcacaataa
     1741 ctgtttcagt ttccatctta ataactgcta cttccatctg ctttttatag ctatcagccg
     1801 atccttcgac agcattattc aataaaacgc tcatgatacg aaccaaatcc aatagttcaa
     1861 ttggaagctt ggtaatcgta tcttttactt ccagtgtaaa ctctacacca ttatttcgag
     1921 catagacaat tgactgagca accaaacttc gtaaagctga atcttctatg ttgttcaaat
     1981 caaagtaagt gtacttatct gaacgcagtt tatgatttgc tttgaccaaa acttcattgt
     2041 aaactctgtc aatttcctgt aaattaccac tgtcaattgc catctgcata ctgacaagca
     2101 tcccagcata atcatgtcga aaaccacgga tttcattata cagaccgaca atttcatctg
     2161 tgtaattctg taaatgtttc tgttcaaatt tcttctgctt caaagcaatc tctttctcca
     2221 tttgaacttt atgagaattc attgcaaaga aggtcaaaag gagagagata aagacaatag
     2281 atgacaaaat acttccaaaa ctattcaaat gtttaatcgt acttaccata tctgaaacga
     2341 aagatacaat atgtagcaat agtaaagcaa aaaatacttt tttcaagaaa ggataaaggt
     2401 agtccttgtc aaaataggct agttccaaat ggaaataata aatgattttt aatgtaacaa
     2461 aataggtcaa caccgtcaca acgaaaaaga atgggaaatg atattgtaaa acaaaattat
     2521 ctcctgttat agaggagaaa gttacggaca gaaagttatg agtgctctca tataaaagag
     2581 atagtagtaa acttaggaat agtcctctat ccctctcata ctgttttatc catcgaaaat
     2641 aggaatatag gcccaaagga aataaaaatg ttgcaatccc taacccatct aaatatagaa
     2701 tatataaggg aaaa
//
LOCUS       DAVHSI010000086         2705 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.095, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000086 DAVHSI010000000
VERSION     DAVHSI010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2705
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.095"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(53..292)
                     /locus_tag="VVR21_002083"
     CDS             complement(53..292)
                     /locus_tag="VVR21_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU6055862.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            complement(344..1780)
                     /locus_tag="VVR21_002084"
     CDS             complement(344..1780)
                     /locus_tag="VVR21_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU6055863.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYKEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(1970..2308)
                     /locus_tag="VVR21_002085"
     CDS             complement(1970..2308)
                     /locus_tag="VVR21_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU6055864.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDEHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            complement(2464..>2705)
                     /locus_tag="VVR21_002086"
     CDS             complement(2464..>2705)
                     /locus_tag="VVR21_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055865.1"
                     /translation="LPTLTTPSVIIMDNARFHRMGKLELLCEEFGYKLLPLPPYSPEY
                     NPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
BASE COUNT          904 a          562 c          352 g          887 t
ORIGIN      
        1 aaagcgtttc caatgacaat tccctcattt tcctaaatga tatggaaaaa aattatttat
       61 acttcaattt ataaaataaa attattcctg agagtagaaa tgaaacacta tttgctaaaa
      121 tcaaaggcaa gtctcctata cgaataccat gagcaagcca caatgcaata ccaataactt
      181 gcataacata catacctaga gcaatagatc ctgtgtcctt tgtcttaact acacgaaaaa
      241 cttgtggtaa aaatgcaaat gttgttaaaa ttgctgcaat acttccaatc atatgtcacc
      301 tcaatatgct aaacaaactg agaataatct cagtttgttt atactattct actgattcac
      361 cgttagatga aataacttcc ttataccagc caaaagattt tttcggggaa cgattataac
      421 ttcccttccc attgtcatct ttatctacat aaataaagcc ataacgtttc cgcatttcac
      481 cggtaccagc tgaaaccaaa tcaatacatc cccatggagt ataacccatt aaatcaacac
      541 catcttcaac tacagccttt ttcatttcac gaatatgggc acctagatat tcaattctat
      601 aatcatcatg taccatacca tctgctgcaa cttgatctat agctccaaaa ccattttcaa
      661 caataaagag tggtaagtga tagtggtctg taaaccaatt taacgcataa cgcaaacctt
      721 ctggatcaat ttgccactcc cattcagaag ccttaacata attatttttc actaaatctt
      781 ccgtttcaag ataatcaaaa taaggattat tttcacgatg agagtcgata gcaaaggaca
      841 tatagtaact gaaaccaatg taatctacag tcccaccaag taaatcttct ttatcctggg
      901 cagtaaaatc aactgaaata ccttttcgtt cccaatactt gaaaatatgc tcaggatatt
      961 tacctaaaac atgcacatca gcaaaataat aacgcttctg catagctttc attgccatta
     1021 agatatcctt aggattgcaa gtagctggat aaattggaca catcgcaatc atacaaccta
     1081 tttgaaaatc tggattaatc tcatgaccaa tttttacagc tcgtgcagaa gcaactaatt
     1141 cgtaatgtgc tgcttgatac ataattgcct ctctattatc accttcctca tatacaatac
     1201 ctgagttagt aaatggtgca aaatcttcct tataattcgc ttgattattg atttcattga
     1261 aagtcatcca atatttaacc ttatctttgt aacgtttaaa tacgacttct gcaaaacgag
     1321 caaagaaatc aatcaatttc ctatttttcc aaccaccata ttcggtcact aagtgataag
     1381 gcatttcaaa atgagataga gtgatgacag gttcaatacc attctttaag cattcatcaa
     1441 aaagattatc ataaaactgt aatccttctt cattcggctc taactcatca ccttttggaa
     1501 agatacgtgt ccatgcaata gaggtacgga agcacttgaa tcccatttca gcaaaaagtg
     1561 ctatgtcttc tttataacga tgataaaaat ctatcgcctc atgatttgga taatatttac
     1621 cctctaaaac tcccgaagta atttcacgag ctactccatg gcgaccagca gtcataacat
     1681 cagcaacact aattcctttg ccaccttctt gccatccacc ttcaagttga tgagcagcaa
     1741 cagcaccacc ccataaaaat ccatctttaa aagtagtcat cttttttcct cctgactttg
     1801 atactcttat tataaacctc aaatcaaaag atgaaaacgc attctttttc cttattgtta
     1861 aggaaagaag taatttttaa tggaaataga acaatatctt cttgtattct cgtaatgata
     1921 tctttacgat tttcaatact ttcaaactac aaaaactctc acaataattc taattccctg
     1981 tgtctataaa cgacttatcg ctttctggca tcccagaatc atcttctata taacgttcaa
     2041 cttgcatctg caagtgatat ttttttctta aatctaagat tttctgcatt gtctttgatt
     2101 gatgatgttc atctaaagct tcttgattta tccactgatc aataaggaga atagttccct
     2161 ctttttcaat tggtaaaaaa tattcgtatt tcaagttacc tttttgattt ctaatttctt
     2221 caacaaggcc actatcaagc atttctcttg caaactttat tgcactatct ccatcacctt
     2281 tataatatac atgaatagtc aatgtcatct tatatcctcc aaaatcatcc ttcaatttta
     2341 aaaaaacaag tttagatgag gatctaaact tgttttttat gaactaatta tctaacgttt
     2401 cgccattact ttcaatcact tctttatacc aataaaatga ttttttctta tagcgattta
     2461 tagtcaattg aaacaagagc aggacaaaag agcctcataa aaggtattgc aacttggtaa
     2521 tacctttttg aggtgctttt tgatatgagc ccatgttttc tcaataggat tgtactcagg
     2581 tgagtaggga ggaagtggta aaagtttata cccaaactct tcacacaaga gttctagctt
     2641 ccccattcta tggaatcttg cattatccat aataataacc gatggtgtgg ttaatgttgg
     2701 taaga
//
LOCUS       DAVHSI010000087         2535 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.097, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000087 DAVHSI010000000
VERSION     DAVHSI010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.097"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..559
                     /locus_tag="VVR21_002087"
     CDS             <1..559
                     /locus_tag="VVR21_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6055866.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VVR21_002088"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VVR21_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU6055867.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2029
                     /locus_tag="VVR21_002089"
     CDS             1424..2029
                     /locus_tag="VVR21_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6055868.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1977..>2535)
                     /locus_tag="VVR21_002090"
     CDS             complement(1977..>2535)
                     /locus_tag="VVR21_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU6055869.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          866 a          364 c          437 g          868 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caatgaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgagc aagtttattt
     1681 aaaacataat cagctaataa cacctgtatc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtcct ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacacta agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tggaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 cctttgatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttattagca taggggaata tcgatataat ggcttcatta
     2221 tgagtggcag gaatatccaa tatggcaact tttccaatag ataatttaaa actcattaat
     2281 aaagttcctt taggtgaaat gtctattttc tttgatttta atgctaattt agaaatagat
     2341 tctctcgtat tagttacata accagatata ggcatatctg atatagatac ccaaggtatt
     2401 tcagttcccc aaaaagtagc ttcactgcgt ggaggagttt ttcctattct gaagttaact
     2461 aggctagcaa atttaatata tctccatgct tctgggattt catatatagg ataagaggtt
     2521 gtttcgtctt tattc
//
LOCUS       DAVHSI010000088         2486 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.098, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000088 DAVHSI010000000
VERSION     DAVHSI010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.098"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..681)
                     /locus_tag="VVR21_002091"
     CDS             complement(<1..681)
                     /locus_tag="VVR21_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU6055870.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDG"
     gene            complement(683..1502)
                     /locus_tag="VVR21_002092"
                     /pseudo
     CDS             complement(683..1502)
                     /locus_tag="VVR21_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
     gene            complement(1504..2457)
                     /locus_tag="VVR21_002093"
     CDS             complement(1504..2457)
                     /locus_tag="VVR21_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU6055871.1"
                     /translation="MKTIKEPGLKGAFRSFFHPKRQVFEAVKDLSFEVPKGQILGFIG
                     ANGAGKSTTIKMLTGILKPTSGFCRINGKIPQENRQGYVKDIGVVFGQRTQLWWDLAL
                     QETYSVLKEIYDVPDAVFQKRMDFLNEVLDLKEFIQDPVRTLSLGQRMRADIAASLLH
                     NPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLGDIEQLCDRIFMID
                     KGREIFDGTVNQLKKTFGKMKTLSFELHPGQDYIVSHFEGLSDIYVTRQELSLDIQYD
                     SSQYQTADIIQQTLSDFTIRDLKMTDANIEDIIRRFYRKEL"
BASE COUNT          923 a          484 c          398 g          681 t
ORIGIN      
        1 tccatccttg tctttcaaga aatagctagc tgggtaatag gctgtaaaag caaaaggaat
       61 gataaaacta atcaaccaac gtaaaaacga atggtaaatc gcaatcgggt attttgcaaa
      121 atcattaaac atgtaaaaaa tataaattat tgccccagat tgtttagtcc aaaaagcaat
      181 actagctgtt acaattttta aagaggtata aattaaggtt gcaaagggaa tactgattaa
      241 aaagagaaaa acctttgccc aagtccaagt aagactagtt attgtcatta acagcaataa
      301 gacgcctact aacaattctc caagagcatc aatttgaaac gtttctacta aaatatgaaa
      361 caaagggcta atgggtctag tcaaatactt atcaaattct cctttacgaa ttaaatgttg
      421 tcctaaagcc cacagattat caaaaaagag atggtcaatt cccttaggaa tgagagaaaa
      481 accataaata aaagcaacct gatgaaaact ccagccatca agtaagggaa tatgttgaaa
      541 caaaatattt agaaacagca tgtttaaccc ttgtgtcaaa aagacaccca caacaccaac
      601 taaaaaatca gccttatact ccataatctg tttaagatat tgtcggataa aaatcaggtg
      661 catgcgttga tatttcttca ttctaacctc cttgaatagt tatataattc tgtacgcact
      721 tccaaatcag ttgggataag gcaatcataa taaacagcca gaataattgt agcgagagcg
      781 cctgaatcat ttgactcatg ctatactttt ctataataac catcaccggg gtatagatta
      841 aagaagaaaa tggcaaaaaa gataatagtt cggcaataat ttttggaaaa aatgtcagag
      901 gaaccaaact tccagataaa aaggcaacta aagaattttt caaaagattt gatccccata
      961 agtttttaaa cacaaaagct gaaaaaccaa agcaaatatt gaaaaaaaaa attaatcaaa
     1021 aaagctaaga ttaagctaag aaggtaaact gtggttatta aaacaatttg taagaaggac
     1081 tcacctgata agagctttag acctgcaatc agaattacaa atggtagacc aacactaaca
     1141 aaaactagcc atctagaccc aatttctgtg aaaagataag acattgcaaa atgaactgga
     1201 cgaagcagtc gcataataat agagccatcc tttacttccc atccaatcat aaaagaacta
     1261 tctgattttg tcagtagatt cgtcacaaaa ctcatgatga tatataaggt catatcagat
     1321 aaagtaaaac cttgaatgag agactggtga gatgaatcaa acacagcttt ccacaagtaa
     1381 aatgctacaa aggcccccat cacatcccca atgcgataaa gaaaaaaatt gacacgatac
     1441 gtgattaatt cttggattcc agcgctaaca aaaggcttat agcgtttcca taatttagtc
     1501 atcctaaagc tcctttcgat agaagcgacg aataatatct tcaatattcg catccgtcat
     1561 ctttaaatca cggatcgtaa aatcagacaa agtttgttga ataatgtcag ccgtttgata
     1621 ctgcgagctg tcgtactgaa tatcaagtga caattcctgt ctcgtcacat agatatcaga
     1681 aagtccttca aaatgagaga caatataatc ctgcccagga tgtagttcaa aagagagagt
     1741 cttcatcttc ccgaaagtct ttttcagttg attcacagtt ccatcaaaga tttctcggcc
     1801 cttatcaatc ataaaaatac gatcacataa ctgttcaata tcacctaaat cgtgggtcgt
     1861 taaaagtatg gtcgtctctt cttcttgatt aatctgtgta atggcacgtc gaatattatc
     1921 cttgaccgaa acatctaaac caatagtagg ctcatctagg aaaagaactt tcggattatg
     1981 caataaggag gccgcaatat ccgccctcat acgttgacct agagatagag ttctgacagg
     2041 atcttgaata aattccttca aatctaaaac ttcatttaga aaatccatgc gtttttgaaa
     2101 gaccgcatca ggaacatcat aaatttcctt taaaaccgag taagtctcct gcaaagccaa
     2161 atcccaccaa agttgagttc gctgcccaaa aactacacca atatctttaa catagccttg
     2221 acggttctct tgaggaatct ttccattgat acgacaaaaa cctgatgttg gtttcaaaat
     2281 ccccgtcaac atcttgatag ttgttgattt ccccgctcca tttgcgccaa taaagcctaa
     2341 aatttgtcct ttgggcacct caaatgataa atctttaaca gcttcaaaga cttgtctctt
     2401 gggatgaaaa aaagagcgaa aagctccctt taagccaggt tcctttattg ttttcacaaa
     2461 atttttctga agatgctcta ctgtta
//
LOCUS       DAVHSI010000089         2289 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.099, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000089 DAVHSI010000000
VERSION     DAVHSI010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.099"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1182)
                     /locus_tag="VVR21_002094"
     CDS             complement(<1..1182)
                     /locus_tag="VVR21_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU6055872.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLKYDRAVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDS
                     RKLSDKHFYRPTFRMHLTNKEILNKLLSYSQDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FE"
     gene            1406..1885
                     /locus_tag="VVR21_002095"
     CDS             1406..1885
                     /locus_tag="VVR21_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU6055873.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            1979..2050
                     /locus_tag="VVR21_002096"
     tRNA            1979..2050
                     /locus_tag="VVR21_002096"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2012..2014,aa:Glu,seq:ttc)
BASE COUNT          768 a          343 c          494 g          684 t
ORIGIN      
        1 ttcaaagttc cgaaaaccaa aggcattgcg cttgataagt ttgatgagat tattggtcgc
       61 ttccaatttg gcgttagaat agtgtagttg aagggcgttg acgattttct ctttgtcctt
      121 tagaaaggtt ttaaagacag tctgaaaaag aggatgaacc tgctttagat tgtcctcaat
      181 gagtccgaaa aatttctccg gttccttatt ctgaaagtga aacagcaaga gttgatagag
      241 ctgatagtga tgtttcaagt cttgtgaata gctcaaaagc ttgtttaaaa tctctttatt
      301 ggttaaatgc atacgaaaag tagggcgata aaaatgttta tcgctgagtt tacgactatc
      361 ctgttgtatg agcttccagt agcgcttgat agccttgtat tcatgagact ttcgatccaa
      421 ttgattcatg atttgaacac gcacacgact catagcacgg ctaagatgtt gtacaatgtg
      481 aaagcgatcc aacacgattt tagcacatgg gaaaagttgt ctagctaagt catagtaagg
      541 actaaacata tccatagtaa taattttgac gcgacatcgg acggctctat catatttaag
      601 aaagtgattt cgaatgatag cttgtgttct tccctcaaga acagtgatga tattgagatt
      661 gttaaaatct tgcgcaatga agctcatctt tccctttgta aaagcatact catcccaaga
      721 cataatctca ggaagacaag aaaaatcatg tttaaagtga aaatcattga gcttacgaat
      781 aacagttgaa gttgagatgg aaagctgatg ggcaatatca gtcatagaaa tcttttcaat
      841 taacttttga gcaatctttt ggttgatgat acgagggatt tggtgattct tcttgacgat
      901 agaagtttca gcgaccatca tttttgaaca gtgatagcac ttgaatcgac gctttctaag
      961 gagaattcta gtaggcatac cagtcgtttc aagataagga attttagaag gtttttgaaa
     1021 gtcatatttc ttcaattggt ttccgcactc agggcaagat ggggcgtcgt agtccagttt
     1081 ggcgatgatt tccttgtgtg tatccttatt gatgatgtct aaaatctgga tattagggtc
     1141 tttaatgtct agtaattttg tgataaaatg taattgttcc atatgattct ttctaatgag
     1201 ttgttttgtc gcttttcatt ataggtcata tgggactttt tttctacaat aaaataggct
     1261 ccataatatc tatagtggat ttacccacta caaatattat agaacctctt ttttgtgcag
     1321 tttaggagct aaagggaaca gaatggagaa aatggaacaa atgtgttttc taatctgtta
     1381 gactgtatct agaaagggga aaattatgat taaagaattg tatgaagaag tccaagggac
     1441 tgtttataag tgtagaaatg aatattacct tcatttatgg gaattgtcgg attgggacca
     1501 agaaggcatg ctctgcttac atgaattgat tagtagagaa gaaggactgg tagacgatat
     1561 tccacgttta aggaaatatt tcaaaaccaa gtttcgaaat cgaattttag actatatccg
     1621 taagcaggaa agtcagaagc gtaaatacga taaagaaccc tatgaagaag tgggtgagat
     1681 cagtcatcgt ataagtgagg ggggtctctg gctagatgat tattatctct ttcatgaaac
     1741 actaagagat tatagaaaca aacaaagtaa agagaaacaa gaagaactag aacgcgtctt
     1801 aagcaatgaa cgatttcgag ggcgtcaaag agtattaaga gacttacgca ttgtgtttaa
     1861 ggagtttact atccgtaccc actagtaagt catgcaaaaa aaatgaaaaa aattagaaaa
     1921 agtagttgac aaagtttgaa aagactgtat aatagtaaga gttgaaaata acaactcagg
     1981 tccgttggtc aaggggttaa gacaccgcct tttcacggcg gtaacacggg ttcgaatccc
     2041 gtacggacta tggtatgttg cgtcaggacc acttgatgaa aaaaagttta aaaaagctta
     2101 aaaatcttca aaaaagtgtt gacaagcgaa agtggctgtg atatactaat atagttgtcg
     2161 cttgagagaa gcaagtgaca aagacctttg aaaactgaac aagacgaacc aatgtgcagg
     2221 gcgctacaac ataagttgta gtactgaaca atgaaaaaaa caataaatct gtcagtgaca
     2281 gaaatgagt
//
LOCUS       DAVHSI010000090         2261 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.100, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000090 DAVHSI010000000
VERSION     DAVHSI010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.100"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            1..180
                     /locus_tag="VVR21_002097"
                     /pseudo
     CDS             1..180
                     /locus_tag="VVR21_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(349..901)
                     /locus_tag="VVR21_002098"
                     /pseudo
     CDS             complement(349..901)
                     /locus_tag="VVR21_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(977..1417)
                     /locus_tag="VVR21_002099"
                     /pseudo
     CDS             complement(977..1417)
                     /locus_tag="VVR21_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1408..1716
                     /locus_tag="VVR21_002100"
                     /pseudo
     CDS             1408..1716
                     /locus_tag="VVR21_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1871..2194)
                     /gene="tnpB"
                     /locus_tag="VVR21_002101"
     CDS             complement(1871..2194)
                     /gene="tnpB"
                     /locus_tag="VVR21_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU6055874.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
BASE COUNT          711 a          465 c          419 g          666 t
ORIGIN      
        1 tatcactgtt caaaaatgat ggtcgctgaa acttctatcg tcaagaagaa tcaccaaatc
       61 cctcgtatca tcaaccaaaa aattgcgcaa aagttaattg aaaagaattc tatgaccgat
      121 attgcccatc agctggccat ttcaacttca actgtcattc gaaagctcaa tgacttccac
      181 gtttacgaga gtttcctcgt ttggaagaca ttctagaaga taggatagat atttctcgct
      241 atttataatg gattgaaata agatatgaac aaatcgatta ggaaaggaaa attgatttat
      301 agaaatgttt tagcagtcga tgcgtactgt tatagattca acgcactata attgatgacg
      361 tttagctgtt tccaacaagc tcataataat agctcttgct ttagctcctt caaaactttg
      421 agaaaataac caccctcgct tttttaaact gagctcaggc taaaagagtc cactggactc
      481 ttttactccg tcccataacc aatgatttaa tggcgcgttc agctagatta ttggaaagga
      541 ccagatgtcc gtctttcaaa atagtcttaa aggtttcttc atacttgagg ctgtattcaa
      601 ttgcccttcc tagttttgaa cctgctaaaa ctgactgacg gccggcacca agcaaagaaa
      661 tcttccatta ggttggagct cttcttgacg tttctgtagt cgttcatcag ctggcaatgt
      721 cctcccagtc tctttccaag gaaaataact gatcacaata ggctaatcct ttagctccta
      781 aggatgattt atctgcttgc ttgggggtcg cttcaaaaaa cttccttctc acatgtgccc
      841 aacatccaac aagttcagct tcttccagtt gacgataagc ttctagcggt tcgcagttta
      901 ccaagcttag cgtcgccttg ctcctaaacc ttggactgct atcgcatagg cagaactaga
      961 ggactaaagt cctaagttac tgccgcaaca tatcacaatg aacatagcca gaataatctc
     1021 ctaggaattc ttgtactacc gaaccactcc gactctgatc atgatggtac agcgtgattg
     1081 cttgattctc aactttccca gacaaaaagg ttcaatagta ggtcagatgg ctatgactct
     1141 ctagaacccg ataagaggtt tcatctgcat gaagaagagc ttgttctaac aacttttctc
     1201 gtaaaagatt ataaaggggc tccaaataat agtgactcgt cttgatatgc caattagaaa
     1261 tttccttacg tgtgattggt aaacccatct tagcccaatc ttcttcttag cgataattgg
     1321 gtaccttcag aataaacttc tgatggatgg tgtgagcgat aatagaagct gagccaaggc
     1381 tatgcgccaa aggggcttta ggaataggag ctttcacaag cttatccaga tgattatctt
     1441 ttactcgtta tggacaatgc tatatggcat aaatcaagta ccttaaagat tccgactaat
     1501 attggctttg catttattcc tccatacaca ccagagatga accccattga acaagtgtgg
     1561 aaagagattc gtaaacgtgg atttaagaat aaagcctttc aaactttgga agatgtcatg
     1621 aatcaacttc aagatgttat acaaggactg gagaaggagg tgataaagtc catcgttaat
     1681 cggagatgga ctagaatgct ttttaaaatc agatgagtat aaaaagaaag tcctcatttc
     1741 aatagaaatc acgactttct gatggattta tagtaaaatg aaataagaac aggacaaatc
     1801 gatcaggaca atcaaatcga tttctaacaa tgttttagaa gcagaggtgt actattctag
     1861 tttcaatcta ctatattttt ggagtgatag aaaagccttt catcagccaa tctacttgtt
     1921 caggtgcgag agctttgaca tccttttctg tacttagcca agtcagtttt ccgttctcaa
     1981 agcgtttata tagtagccaa aatccttgac catcccagta aaggacttta aagcggtctt
     2041 tacgtccacc acaaaagaga aaaacttgac ctgagaaaga atccaattca aagtgggttt
     2101 taaccagata agccagtgaa tcgattcctt gtctcatatc cgttttccca catacgagat
     2161 agacctgccc taggctagat agatgaattg tcatagagca acaccttatc caaaagctgt
     2221 tctatcattt cgagattgag agattgaaaa aaacttactt c
//
LOCUS       DAVHSI010000091         2151 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.102, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000091 DAVHSI010000000
VERSION     DAVHSI010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.102"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(39..2021)
                     /locus_tag="VVR21_002102"
     CDS             complement(39..2021)
                     /locus_tag="VVR21_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU6055875.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT          589 a          459 c          373 g          730 t
ORIGIN      
        1 aagagaaata ctaaatcctt tcttatattt tgcaacagtt atttcacatg ttttgcgaga
       61 tcttcttgag cctttttatt agactcttct ttttctttca tccatttttc ctgagctttt
      121 tgatattcat ctacagtgac tgccttgtct tgaagttcca agtatttata caagactggt
      181 tcacttgtac ctttatttcc tgacaatgca aatggtattg taaatggtac catcttagac
      241 aagattggac gccctgtacg agatgtagtt ggaataatca aagcactatc tgtcaaccaa
      301 gcttgggctg cagcgtattt atcatagcgt ttagcaacat ctgtagtctc atcaccagcc
      361 tcagtaacca atttttcgta gtcatataga cctacttttt tagcagctac attatcttcc
      421 cctgagtcaa accctaaata tgttttagta ctttctccta cagatggttt gatgatatca
      481 aggtaggttg atggatcggc aaagtctgga ccccaaccga cattatctga taaatcccag
      541 tcttcgccag cagcattttc agcaaaatat gtaatattgt ttacttcgtc tttttgtagt
      601 tgttgaatat caatgactac attatccgct cctaaagttg cttccaagga ttgtttcata
      661 gattggacgc gctgaacttt tgtagttgct gtttggtcaa ctggcatatc caaatgaatt
      721 gggaatgtca caccttctgc ttgtaaggct gatttagctt tagcaaattc agccttggct
      781 ttttctggat tgtaaagacc atcctgagaa tctgcaagat taacatcctt ccattcatcc
      841 ccataagtaa ccaatttctc tttgaccata tcgccaaagt ttttaccatc tgcttgaaca
      901 aatgttggtg gaacaaagat attacgtaag attttgcttg ctccagtttg tccattcaac
      961 tgagaggcat aggctgtacg atcaaaacca aaggcaatag cctgacggaa atccttgttt
     1021 aagagagcct ttttagtcga tgccttttgt tcgtcgctgg tcttagatgt gtatttatag
     1081 gactgacggt caatatttgt accaactaga tacgtaatag agtcttgttg agtatagaca
     1141 atattgtcct tcatactctt ctcaagctct gcgaaacttg cacttgttgg atagagacga
     1201 gctgctgtaa ggctaccatc tttaaagttt tctgcaggtt tgctggtatc ttgaccatcc
     1261 cagaatgaca atttaacttt gtcaatatgc acattgtcct tatcccagta gttcggattt
     1321 ttcgcaaatt caacagaaga tttggtcaca atggatttca acaaataagg accgttatac
     1381 aagagactac ttggatccgt agctttggca aaatcatccc cttttgaatt caaaaactct
     1441 tcattaactg gcgcaagcac acccatggtt gtcttagaat tccagaagct ttctggtttg
     1501 ttcaaagtgt actgaactgt ctgttcatcc agagccttaa ttcctacttg tgagaaatct
     1561 ttgatttccc cttttacata ggcatccaac cctttgattg attcttgaac aaggtaaaga
     1621 gcatctgatt ttttatcagc agcatatttt agtcctgtta caaagtcttg agctttgact
     1681 gccgcgtatt cttcaccttc agaagtatac cattttgcat ccttacggat agtataagtg
     1741 taagtcaatc catccttgga tacagaccaa tcctcagcca tagacggcac aaagttcccg
     1801 tagcgatcat tttctagcaa accatcaacc acgttactgg taatatttgc tgtcgcagcc
     1861 ttagcagttg tcaaatagtt gaggttatca gggtctgtct cataaatgta tgagaatgtc
     1921 ttctcacctt tagtgcttga acctgatcca gagcatgcag ctaaagtagt cgccgccaat
     1981 aatgtcacgc ccgcaagggc aaatagtctt gaacttttca tcattttctc ctttaaaact
     2041 ttctctccat tatagactct tttcagaaag ttgtcaacag aattttcaga atttttgaaa
     2101 attatttttc aaacaacatc tttgcaaaaa atatccccaa ttattcaccc c
//
LOCUS       DAVHSI010000092         1996 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.103, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000092 DAVHSI010000000
VERSION     DAVHSI010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.103"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..801
                     /locus_tag="VVR21_002103"
     CDS             <1..801
                     /locus_tag="VVR21_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU6055876.1"
                     /translation="AHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTLSNFTLEN
                     YRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFEYGALLPW
                     LLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVRAILFSVD
                     DEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFLYHPLAQP
                     LGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            804..1514
                     /locus_tag="VVR21_002104"
     CDS             804..1514
                     /locus_tag="VVR21_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU6055877.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            1610..1978
                     /locus_tag="VVR21_002105"
     CDS             1610..1978
                     /locus_tag="VVR21_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055878.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
BASE COUNT          603 a          279 c          362 g          752 t
ORIGIN      
        1 gctcacattg tagcatatgg attgttcaca gttttcatgc ttccactaat ttttatagta
       61 ttatactcat ttacagatcc agttgcaatt caaacaggta acttaacatt atcaaacttt
      121 actttagaaa attatcgctt attctttagt aatagtgcgg cattctctcc attcttggtc
      181 agctttattt attctattat tgctgcgaca acagcaacaa ttctcgcagt tgtatttgct
      241 cgtgttgtca gaaaacataa atctcgtttt gatttcttat ttgaatatgg tgctctactt
      301 ccttggttac taccaagtac acttttagca gtaagtttat tatttacttt taatcaacca
      361 caatttcttg tcttgaatca gattttggta ggtagtttgg taattctact tattgcatat
      421 atagttgtaa aaatcccatt ttcttataga atggtacgtg ctattttatt tagtgttgat
      481 gatgagatgg aagatgcagc aagaagtatg ggtgcttcac ctttttatac tatgatgaag
      541 gttatcattc catttatttt accggttgtt ctctctgtta ttgctttaaa ctttaactct
      601 ttattaactg acttcgactt atctgtattc ctttaccatc ccctagctca accattaggt
      661 attacgattc gatctgcagg tgatgaaaca gcaacatcta atgcacaagc tctggtattt
      721 gtttatacaa ttgttctgat gattatttct ggaacggtat tatacttcac acaaagaccg
      781 gggcgtaaag taaggaaata atcatgacag ccactagtct tgggttatca aatattgaaa
      841 tagttgtcag gattgtttta tcagtagtca ttggtagtat aattggttta gagagaggga
      901 gcaaatccca gcctgcaggc atccgaactt atagtattgt ttgtctagct gcatgtttga
      961 ttatgatgac gaatgaatac gtatcttata aatttgggac aggagatcct acacgattag
     1021 gagctcaagt tatatcaggt gtgggttttc taggcgctgg aacgattctt attacagata
     1081 aaaagaaaat tacaggtctg acaactgcag caggcatttg ggcttcggca ggaattggat
     1141 tagctattgg agtaggtttt tatgagggag ctcttttagt agccatttct gtttggggtg
     1201 tgatatccat gttccaacca ctaaaaaaat atctgcaaaa tcgttctaaa atgattgaat
     1261 tgtatatagt agttaaatct acagaagcct ataatcgtgt attggtttat tgtgcagaaa
     1321 atggtatcag aatgaccgat tcaagaacag cgtttggaga tgttaattct gacagaattg
     1381 aatactttga tgttccggac aaaaaaatag cgtcatttat tactctggaa ttatcaggta
     1441 gatttgaaca tcttcgactg atggaagaaa ttgctaatat tgtaggtgtt atttatgtcg
     1501 aagaaattag ctgaaattta gtaaacaaag ggacagatgt ttttgtcctt ttgcttttta
     1561 gatgttttaa tcatctaatt tttgagtaga tttttgctca gaggttttta tgaaagatta
     1621 taaaatcaat tttgatttag gtaaaataga atattttgat aataattgtt tgatacaagt
     1681 atacaaattt atttcttttt atgatatttg tgaaatggtg tttgcctttc atttacctcc
     1741 tgatgagttg ataacaaatg ttatctttaa agaaaaaatt aactctatgt taaaatgtta
     1801 cattgacagg ctattatatg tttttataaa tcctacacat tttactgaaa aagttaatct
     1861 acaattttat ggtagttttt tctcatatga atttatttgt cgtgaagttg gaaacattct
     1921 taaaaataaa ggtgtgaaat gcaatttaaa cttttttgaa ggggaagaat atttgtaaaa
     1981 ttaattttgt gaattt
//
LOCUS       DAVHSI010000093         1911 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.104, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000093 DAVHSI010000000
VERSION     DAVHSI010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1911
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.104"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            314..1513
                     /locus_tag="VVR21_002106"
                     /pseudo
     CDS             314..1513
                     /locus_tag="VVR21_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT          628 a          400 c          343 g          540 t
ORIGIN      
        1 ataataagta atcgcccaat ctgaccttct ccagaacttg attattcgtc aatcactaca
       61 gttgacaaac atactaagat tagtagtgag gaaatctcca acgggagaga gtactcatta
      121 ctttttcttt gtgttaaaat agtggtgtct tgttaagtca tagagctctc tatggtgcta
      181 gacgtcgctt gacaaactgg caagaaacct gttttaggaa gaattttatc aaagtatgtg
      241 ggatactaga cgtcgagtat tggaaataaa atcactaaaa caaggagtca ttcaagacaa
      301 aggggtaaac atgatgcgga cagttttcag aatggatgtg agtaaggcaa gctcagaagt
      361 cgctattctt gtgaatggtg aaaaggttca tggctatacc atgcccaatg atgccatcgg
      421 atttagtcgt cttctagagg atttgaaata ggtaaataca cctgagatta tcttcgaggc
      481 acagacaggg gtctattctc gtcttcaggc ctttctggag gacaatagct atgcttatat
      541 acggctaaat cctttaaaac taagaagcaa ctagacagtt tgcgagtccg taaaaccaat
      601 cagattgacg ctgaaaagct agcttcgtca caattcatcc ttaaccgcaa accaacttat
      661 gttcaagaag aagtctatca aaatttgcgt gacctcagtc gattctatca gaatctgaca
      721 gaagacatcg ttaggactaa gaatagcctg cacaaggtgc ttcaaattgc ctttccagaa
      781 ataaagaacc ttctctctac tcctacaggg gaacaatatt ggaacctcgt gaccatcttt
      841 ccaaccaagc attggaggct gaaattatca gtagttgagc taaaagaagc catcgtaatt
      901 caacttctaa acggatttct gagaacagag ttggacgatt ggctgaaaag ttgagcgagc
      961 tggccgaaca gtcctatctt gccatttcaa aaacctctcc catgacagaa gaggttaagt
     1021 atcatgcaca ggaactgttg agactgacaa accgcaagga tcaggactta gcacaaatga
     1081 ttgaattggc tgaaccatta cctgaatacg agattctgct ctctattcct ggtatcgcag
     1141 aaacaacagc tacaagcatt attggcgaat tggagacatt cgtcgctttc agtctgccaa
     1201 ccaaatcaat gcctttatca gtattgacct cagacactat gaatctggca atttcctagc
     1261 tcaagaacat atcaccaagc gtggaaatcc ttacgcgaga aaaattctct ataagtgcgt
     1321 ccacaatatt gcttcagcta gtcataccaa tccttgtcat atcgcggact tttatgagaa
     1381 acgaaaaaga caatcgcaga cgacttcaac caagccatat acgattgtct ctatacatcg
     1441 cctcatccgg acaatgtatt acctcataac gcataacaaa ctttacgact acactttaac
     1501 ccaaagtcat taaagtcatc tatgtcctat cattgtaaca ccttattttt taataccaga
     1561 taagtgtctt ttaagtgtgc ccaaatttca aaaaacagct cgcaattatc ttctaaacat
     1621 tcctttgata ctcattcaga aaaccttttg agctagaata tcgtatgtcc cttaacaaat
     1681 ggtatgtata aaagagctaa aaaaccactc atgatatgaa cgagtggtta tgactgaaat
     1741 attacatacc tttgtatcat ttttgcacaa tggtcaaatt tcttgtttga aaaactacag
     1801 taagcctaat caaagctctc aatgtatcat taaaacttcc ttccaaagaa taggaagttc
     1861 tatcaaaatt cttaattaga ttttacttct tctaagaccc tgcgctctca t
//
LOCUS       DAVHSI010000094         1837 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.106, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000094 DAVHSI010000000
VERSION     DAVHSI010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.106"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..803)
                     /locus_tag="VVR21_002107"
     CDS             complement(<1..803)
                     /locus_tag="VVR21_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055879.1"
                     /translation="MFNSSCALFIVSCETNQQVVNLLIQSMRQQISHMVSIYVSSDGP
                     LLITDPSVRVLIGQEEVFGDRVATALEQVTEERVIVFCDDFIVEKPAKIEELEELLSL
                     MEEDTSIASIALSQISGGNTPERIAEHYIRRTKYAPYKTTLQCAIWKKSSLIQFMKGS
                     PSPWEFEIYHNFKTYLTKEKFYALEDDMFQPIPYNRGKLIIRGKVVKPEKERLEELLG
                     YSLDLSDFPETESFVQGENLTVGYRLKRKIKLLEKEIIYRLKSKIKNKK"
     gene            complement(796..>1837)
                     /locus_tag="VVR21_002108"
     CDS             complement(796..>1837)
                     /locus_tag="VVR21_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU6055880.1"
                     /translation="FRVMLLDELAKHAEVTLFYVHEIEAGVKAEYVKLRPVRTKLQSI
                     TELGLFQTFQMLKEMDMVFFDGYTGWEKMFLMSSMWLTRRQYAISVDGIINHSNISLK
                     QRLLDFIKSVALSKAEFVLSTNTPTDAYIQQLAPKAKIKRHIFSTLSQDDFKNMIEVA
                     SDTVFTRYSIRKSEKNLLFVGQFINRKGVDELLAFMKEHEADTSLQLIMVGGTREELS
                     VFETEIPSNIHIIPFLEKTDILELMRVADVFVLPTREDIWGLVIIEALSMGIPIVSTD
                     RCNAALEFVRDGENGYLMQEVTAVELANKLKATFKLDAEHVARYDQKLMQDYNLEGSA
                     KNIMDILEGSHV"
BASE COUNT          572 a          412 c          285 g          568 t
ORIGIN      
        1 tttttcttat tctttatttt agatttcaaa cgataaataa tttctttttc taacaattta
       61 atctttctct tcaaccgata gcctacagta agattttccc cctggacaaa agactccgtt
      121 tctgggaaat ccgataaatc taatgaataa cccaaaagtt cctccaaacg ttctttttca
      181 ggtttaacaa ctttacctcg aataatcaac tttcctctat tataagggat aggttggaac
      241 atatcatcct ctaaagcata aaatttctct ttcgtcaggt aagttttaaa gttatgataa
      301 atctcaaatt cccaaggaga gggactcccc ttcatgaatt gaatcaaact agacttcttc
      361 caaatagcgc attgaagagt tgtcttatag ggggcatatt tcgtgcgtct tatataatgc
      421 tcagcaatac gctcaggtgt attccctcca gatatttgtg acagggcaat actagcaata
      481 cttgtatcct cttccattag agacagtagt tcttctaatt cttcaatttt agctggtttt
      541 tctacgataa agtcatcaca aaaaacaatg actcgctctt cagtaacttg ttccaaagca
      601 gttgcaacac gatctccaaa aacttcttcc tgaccaatca aaacccttac gctaggatcc
      661 gtgattaaca atgggccatc tgatgataca taaatggata ccatatgaga aatctgctga
      721 cgcatggact ggatgaggag attgactacc tgctgattag tctcgcaact aacaataaat
      781 aaagcacaag atgaattaaa catgacttcc ctccaagatg tccataatat tttttgctga
      841 accttccaga ttatagtctt gcatcagttt ttgatcatag cgagcaacat gctcagcatc
      901 tagtttaaag gtagccttaa gcttgttagc caattctacc gcagtcactt cctgcatcag
      961 ataaccattt tcgccatccc taacaaactc caaggctgcg ttacaacgat ccgtagaaac
     1021 aataggaatg cccattgata gcgcctctat aataaccagt ccccaaatat cttctcgagt
     1081 gggcaaaaca aagacatctg ccacccgcat caactctagg atatcagttt tttctagaaa
     1141 aggaattata tgtatattag aaggaatctc tgtttcaaaa actgacaatt cttctcttgt
     1201 acctccgacc ataattaact gcaacgaagt atcagcttcg tgctctttca taaaagccaa
     1261 aagctcatcg actccttttc tattgataaa ctgtcccaca aaaagcagat ttttctcaga
     1321 ttttcgaata ctatatcttg tgaaaaccgt atccgaggca acctctatca tgtttttgaa
     1381 atcatcttgt gaaagagttg aaaatatgtg tcgtttaatc tttgccttgg gagctaattg
     1441 ctgtatataa gcatctgttg gggtattggt gctaagcaca aactccgctt tgcttagagc
     1501 aacagactta ataaaatcca acagtctctg cttaagtgag atattactat gatttattat
     1561 accatcaaca gaaatagcgt actgccgtct tgttagccac atactgctca tcaagaacat
     1621 cttttcccac ccagtatagc catcaaagaa gaccatatcc atctctttca acatttgaaa
     1681 cgtctgaaat aaacctagtt ctgtgattga ttggagcttg gtacgaacag gtcgtagctt
     1741 gacatactca gcctttaccc ccgcctcaat ttcgtgcaca taaaaaagag tcacttctgc
     1801 atgcttggct aactcatcta ataacataac cctaaaa
//
LOCUS       DAVHSI010000095         1802 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.108, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000095 DAVHSI010000000
VERSION     DAVHSI010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.108"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..1145
                     /locus_tag="VVR21_002109"
     CDS             <1..1145
                     /locus_tag="VVR21_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU6055881.1"
                     /translation="LLVVIVISFFSGALGSFSITQLTQKSSVNNSNNNSTITQTAYKN
                     ENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSEGSGVIYKKNDKEA
                     YIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISSEKVTTVAEFGDSS
                     KLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAISTKAIQTDTAINP
                     GNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINIIEQLEKNGKVTRP
                     ALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHLEKYDVITKVDDKE
                     IASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLES"
     gene            1203..>1802
                     /locus_tag="VVR21_002110"
     CDS             1203..>1802
                     /locus_tag="VVR21_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU6055882.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHTEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQ"
BASE COUNT          638 a          327 c          344 g          493 t
ORIGIN      
        1 aattattagt cgttatcgtc attagctttt ttagtggagc cttgggtagt ttttcaataa
       61 ctcaactaac tcaaaaaagt agtgtaaaca actctaacaa caatagtact attacacaaa
      121 ctgcctataa gaacgaaaat tcaacaacac aggctgttaa caaagtaaaa gatgctgttg
      181 tttctgttat tacttattcg gcaaacagac aaaatagcgt atttggcaat gatgatactg
      241 acacagattc tcagcgaatc tctagtgaag gatctggagt tatttataaa aagaatgata
      301 aagaagctta catcgtcacc aacaatcacg ttataaatgg cgccagcaaa gtagatattc
      361 gattgtcaga tgggactaaa gtacctggag aaattgtcgg agctgacact ttctctgata
      421 ttgctgtcgt aaaaatctct tcagaaaaag tgacaacagt agctgagttt ggtgattcta
      481 gtaagttaac tgtaggagaa actgctattg ccatcggtag cccgttaggt tctgaatatg
      541 caaatactgt cactcaaggt atcgtatcca gtctcaatag aaatgtatcc ttaaaatcgg
      601 aagatggaca agctatttct acaaaagcca tccaaactga tactgctatt aacccaggta
      661 actctggcgg cccactgatc aatattcaag ggcaggttat cggaattacc tcaagtaaaa
      721 ttgctacaaa tggaggaaca tctgtagaag gtcttggttt cgcaattcct gcaaatgatg
      781 ctatcaatat tattgaacag ttagaaaaaa acggaaaagt gacgcgtcca gctttgggaa
      841 tccagatggt taatttatct aatgtgagta caagcgacat cagaagactc aatattccaa
      901 gtaatgttac atctggtgta gttgttcgtt cggtacaaag taatatgcct gccaatggtc
      961 accttgaaaa atacgatgta attacaaaag tagatgacaa agagattgct tcatcaacag
     1021 acttacaaag tgctctttac aaccattcta tcggagacac cattaagata acctactatc
     1081 gtaacgggaa agaagaaact acctctatca aacttaacaa gagttcaggt gatttagaat
     1141 cttgattgac atctatgtaa agaaagcttt acataagaga aaagatgtgt tagtgtagaa
     1201 tcatggaaaa atttgaaatg atttctatca cagatataca aaaaaatccc tatcaacccc
     1261 gaaaagaatt tgatagagaa aaactagatg aactagcaca gtctatcaaa gaaaatgggg
     1321 tcattcaacc gattattgtt cgtcaatctc ctgttattgg ttatgaaatc cttgcaggag
     1381 agagacgcta tcgggcttca cttttagctg gtctacggtc tatcccagct gttgttaaac
     1441 agatttcaga ccaagagatg atggtccagt ccattattga aaatttacag agagaaaatt
     1501 taaacccgat agaagaagca cgcgcctatg aatctctcgt agagaaagga ttcacccata
     1561 ctgaaattgc agataagatg ggcaagtctc gtccatatat cagcaactcc attcgtttac
     1621 tttccttgcc agaacagatt ctctcagaag tagaaaatgg caaactatca caagcccatg
     1681 cgcgttccct agttgggtta aataaggaac aacaagacta tttctttcaa cggattatag
     1741 aagaagatat ttctgtaagg aagttagaag ctcttctgac agagaaaaaa caaaagaaac
     1801 ag
//
LOCUS       DAVHSI010000096         1768 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.109, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000096 DAVHSI010000000
VERSION     DAVHSI010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.109"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            160..429
                     /gene="blpJ"
                     /locus_tag="VVR21_002111"
     CDS             160..429
                     /gene="blpJ"
                     /locus_tag="VVR21_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU6055883.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            498..728
                     /gene="blpU"
                     /locus_tag="VVR21_002112"
     CDS             498..728
                     /gene="blpU"
                     /locus_tag="VVR21_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU6055884.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            731..850
                     /locus_tag="VVR21_002113"
     CDS             731..850
                     /locus_tag="VVR21_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU6055885.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1147..1311
                     /locus_tag="VVR21_002114"
     CDS             1147..1311
                     /locus_tag="VVR21_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055886.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            1308..1712
                     /locus_tag="VVR21_002115"
     CDS             1308..1712
                     /locus_tag="VVR21_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU6055887.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
BASE COUNT          548 a          233 c          376 g          611 t
ORIGIN      
        1 attgaaatct tagactaaaa aataggtact gctaccttta agaagatagt agacgtgtat
       61 acttttttaa gaaaatcaaa aagatactat aaaaaatcta tttgtttatt gaatttaaga
      121 ctttggtaac aaattgaaaa taaaaaggag gtattcatca tgaatacaaa aatgttgtca
      181 cagttagagg ttatggatac tgaaatgctt gcgaaagttg aaggggggta tagctccact
      241 gattgtcaaa atgcactgat tacaggagtc actacgggaa ttataactgg tggaactgga
      301 gcaggtttgg ccactttagg agtagctgga cttgctggtg catttgttgg agcacacatt
      361 ggtgcaattg ggggtggatt aacatgctta ggaggtatgg ttggtgataa attgggacta
      421 agttggtaag acttatagta aaattatgag gattctattc tgatttattt tagtttttta
      481 aaaaaggagt atttgtcatg gatacaaaaa tgatgtcaca attttctgtt atggatactg
      541 aaatgcttgc ttgcgttgaa ggtggcggat gcaattgggg agattttgcc aaagcaggtg
      601 ttggaggagg agcagcaaga ggtcttcaac taggcattaa aacaggaaca tggcaaggtg
      661 cagcaactgg tgctgcgggt ggagctatac ttggaggtgt agcctatgca gcaacatgtt
      721 ggtggtaatt atggatttta aaagttttat tattggttta gtagttggta tatttggtcc
      781 ttatatggat aatttaatta gaaaaatatt ttcaaaattt cccaaaaagg atacagatag
      841 taccccctaa aaaataaatt tctcccctgt atttgctagc ttaatttaca ggggagtttc
      901 tttaattttg tttcgcctgt caaaatgata tgtgatagca ggatgaaaag tctgcaaaca
      961 agttggtatc aatacaatat aaagaggaaa gtatgttttt catgcttgct tttttaattt
     1021 ttacaattca agaggttttg atgaccattt atgatttgag tgatccaagg tcaaaataag
     1081 tgctatacta gcagtgtaaa tgttcttgct caactaagat aaatcgcaca tttaggagga
     1141 aatcttatga agaaaaaaat actgattatt ttcgttctgt atctaatcat gtccatcttt
     1201 ctatatccgc ttagggagag tgcttggtat cagctatttt ataccatagc ctatgtgatt
     1261 gcagttatga tctattttgc tatcaataaa aagaaaggag aaaagaaatg aaaacttttc
     1321 ttgctaaaaa acggaacatc ttccttgcga gattgttctt aggtcagttg cccttgcttg
     1381 tttctactta tctatttcta tctcgtcagt ttttaaattt ttccgtagtt ttccaatttc
     1441 ttttagtagt tattaacttg gcttctattt tggttactgt ttatctcact agggaaatga
     1501 ggataagaga gtttgaagat gatgatttgg ttagtcctag aaccaatcaa cttatgttta
     1561 tcggcttgac aggttttatg tctattattt gtttgtatag aggtatcaca gcaggagaat
     1621 cttatcaaca actaatcgct tatattggcg ctgttctctg cttaatcatc atgcttctgc
     1681 tcatgtgggg cttgaagtat tataaaaagt agagcttaat gaagtataaa agaaaagggt
     1741 aagtgttttt gcaatactta ccctttta
//
LOCUS       DAVHSI010000097         1617 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.112, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000097 DAVHSI010000000
VERSION     DAVHSI010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.112"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(60..507)
                     /locus_tag="VVR21_002116"
                     /pseudo
     CDS             complement(60..507)
                     /locus_tag="VVR21_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(583..1359)
                     /locus_tag="VVR21_002117"
     CDS             complement(583..1359)
                     /locus_tag="VVR21_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055888.1"
                     /translation="MFAHLDNSVFLKRNKIWKKTLTYPVEREEITYKRKKSKGKRQAL
                     LAQFDSEEVYHQVEESIYPDCQGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQA
                     CSDKNPSDKIVKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWAKMGLPI
                     TRKEIANWHIKASQYYLEPLYNLLREKLLEQALLHADETSYRVLESDSQLTYYWIFLS
                     GKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(1283..1477)
                     /locus_tag="VVR21_002118"
     CDS             complement(1283..1477)
                     /locus_tag="VVR21_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU6055889.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
BASE COUNT          451 a          346 c          308 g          512 t
ORIGIN      
        1 tgctttagct ccttcaaaaa ctttgagaaa acaaccaccc tcgctttttt aaactgagct
       61 taggctaaaa gagtccactg gactctttta ctccgtccca taaccaatga tttaatggcg
      121 cgttcagcta gattattgga aaggaccaga tggtccgtct ttcaaaatag tcttaaaggt
      181 ttcttcatac ttgaggctgt attcaattgc ccttcctagt tttgaacctg ctaaaactga
      241 ctgacggcgg caccaagcaa agaagtcttc cattaggggc tggagatgtt cttgacgttt
      301 ctgtagtcgt tcatcagctg gcaaagcctc ccagtctctt tccaaggaaa ataactgatc
      361 acaataagct aaacctttag atcctaagga tgatttatct gcttgcttgg gggtcgcttc
      421 aaaaaatttc cttctcacat gcgcccaaca tccaacaagt tcagcttctt ccagttgacg
      481 ataagcttct agcggttcgc agtttaccaa gcttagcgtc gccttactcc taaactttgg
      541 actgctatcg cataggcaga actagaggac taaagtccta agttactgcc gcaacatgtc
      601 acaatgaaca tagccagaat aatctcctag gaattcttgt actactgaac cacttcgaca
      661 ctgatcatgg tggtaaagcg taatcccttg tttctctgct ttacctgaca aaaaaatcca
      721 atagtaagtc agctgactat cactttctag aacccgataa gaggtttcat ccgcatgaag
      781 aagagcttgt tctaacaact tttctcgtaa aagattataa aggggctcca aatagtattg
      841 actcgccttg atatgccaat tagcaatttc cttacgtgtg attggtaaac ccatcttagc
      901 ccaatcttct tcttggcgat aattgggtac cttcagatta aacttctgat ggatggtgtg
      961 agcgataata gaagctgagc caaggctatg cgccaaaggg gctttaggaa taggagcttt
     1021 cacgatttta tcactcggat ttttatcact gcatgcttgg cacttataag cgtgttggat
     1081 atgatctatt cgttttaatt gcgcaggaat aaagactaat tcttgtcgtt gaagggttgc
     1141 tccaatctct tttagatctc cctgacaatc agggtaaatg ctctcttcta cttgatgata
     1201 aacttcttct gaatcaaatt gggcaagaag agcttggcgt ttccctttag atttcttacg
     1261 tttataggtg atttcttctc tttcaactgg gtaagtcaga gtcttcttcc atattttgtt
     1321 cctcttcaaa aagactgagt tgtccagatg ggcaaacact tttctcagag gattttccat
     1381 agagcttttg cgttagataa gccacttgtt cacgaagaag ggcaagttca ttggtgagac
     1441 tatcaattgt agcactctgt tgttgaatga ttttcaatct tcttccatgg gcttcctctc
     1501 cttatttcct aactttatta taactaaaaa gaaagtcctc atttcaatag aaatcacgac
     1561 tttctgatgg atttatagta aaatgaaata agaataggac aaatcgatca ggacagt
//
LOCUS       DAVHSI010000098         1519 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.114, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000098 DAVHSI010000000
VERSION     DAVHSI010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.114"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            163..>1519
                     /locus_tag="VVR21_002119"
     CDS             163..>1519
                     /locus_tag="VVR21_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU6055890.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKI
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YD"
BASE COUNT          505 a          246 c          304 g          464 t
ORIGIN      
        1 tatcatatac ctacggcaag gtgaagctga cgtggtttga agagattttc gaagagtata
       61 aaatattcag gtgacgcata gatatagtta attgaagctt tgtttgaaat ctgataaaat
      121 aatgatatta ctaagtttta aaaactaaag aaaagggaag atatgattac aggcgaatta
      181 aaaaataaaa tcgatcagct gtgggaaatt ctttggacag aaggaaacgc aaatccttta
      241 acaaatattg aacagttgac ttatctctta tttatgaaag atttggatag tgtcgagctt
      301 ggacgtgaaa gtgatgctga atttctaggg attccttatg agggagtttt tccaaaagat
      361 aaacctgaat accgttggtc aacttttaaa aatataggag atgctcagga agtttatcgt
      421 ttaatgactc aggagatttt tccgtttatt aaaaatctca agggggatac agatgataca
      481 gccttttcac gatatatgcg agaagctatt tttcaaataa ataaacctgc tacgcttcaa
      541 aaggcaattt ctatcttaga tgtttttcca actaggggat tagatgtaga ttttgataat
      601 gacaaacaaa gtattactga tatcggagat atctatgaat atctgttatc aaaattgtcg
      661 accgcaggta aaaatggaca gttccgtaca cctcgtcaca tcatcgatat gatggttgag
      721 ttgatgcaac cgactatcaa agatatcatc tcagatcccg ctatgggttc tgctggcttc
      781 ttagtatctg ctagccgtta cttaaagcgt aagaaagatg aatgggaaac caatacagat
      841 aatatcaatc attttcataa tcagatgttt catggaaatg atacggatac gactatgttg
      901 agacttgggg cgatgaacat gatgctacat ggagtagaaa atccacaaat cagttacctt
      961 gactcgctgt ctcaagataa tgaagaagcc gataaatata ctttggtttt agcaaatcct
     1021 ccttttaagg gctcacttga ctacaattca acctctaatg accttcttgc aaccgtaaaa
     1081 accaaaaaaa cagaattact ctttctttct cttttcttgc gaactttaaa accaggtgga
     1141 cgagcagcag ttatcgtacc tgatggtgtc ctttttggtt cgtctaaagc tcataaagga
     1201 attcgtcagg aaattgtaga gaatcataag cttgatgctg taatctcaat gcctagtggt
     1261 gtgttcaagc cttatgctgg agtttcaact gccattctca tctttacaaa aactggtaat
     1321 ggtggtactg acaaaatctg gttttacgat atgaaagcgg atggtttaag tttggatgat
     1381 aagcgacaac cgattagcga caatgatatt ccagatatta tcgaacgctt tcatcatctt
     1441 gaaaaagaag cagaacgtca gagaacggat caatctttct ttgttccagt tgctgagata
     1501 aaggaaaatg attatgatt
//
LOCUS       DAVHSI010000099         1292 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.119, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000099 DAVHSI010000000
VERSION     DAVHSI010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.119"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            117..1268
                     /locus_tag="VVR21_002120"
     CDS             117..1268
                     /locus_tag="VVR21_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU6055891.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASTEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
BASE COUNT          305 a          243 c          292 g          452 t
ORIGIN      
        1 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
       61 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
      121 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
      181 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
      241 ttgagctctt ggtgagcttg ccttcctttg gaatcatgat gatgttactg ctaaatggtt
      301 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
      361 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
      421 tctttggttt gggtcttggg atgatcaatg ccaaggctat ttctattatc agtgaacgct
      481 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctacagag gtcgttggag
      541 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
      601 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
      661 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
      721 aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta
      781 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
      841 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
      901 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
      961 aaatcgtgat tgccttgtct tcatctttgt gggtggtagt agcaggaagt gttctggctg
     1021 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
     1081 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
     1141 cgaccccatt cgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
     1201 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
     1261 gagcttagga ttgattccta agtttttctt tt
//
LOCUS       DAVHSI010000100         1258 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.120, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000100 DAVHSI010000000
VERSION     DAVHSI010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.120"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            102..629
                     /locus_tag="VVR21_002121"
     CDS             102..629
                     /locus_tag="VVR21_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU6055892.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            641..1156
                     /locus_tag="VVR21_002122"
     CDS             641..1156
                     /locus_tag="VVR21_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU6055893.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(1153..>1258)
                     /locus_tag="VVR21_002123"
     CDS             complement(1153..>1258)
                     /locus_tag="VVR21_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA mismatch repair protein MutT"
                     /protein_id="HEU6055894.1"
                     /translation="FYDMLPLMEMMVAPDKSEFFYPRRTEDDWEKKIF"
BASE COUNT          351 a          266 c          236 g          405 t
ORIGIN      
        1 cttttaacta aaaaatgatc tataaaccca agtaaattct tgctttattg tctggtttat
       61 tgtaccatac tagtgtatat gcagttaaaa aggagattct tgtgaataca cggaaaaaga
      121 cacaatttat gacaatgaca gcccttttaa cggctattgc gattttgatt ccaattgtta
      181 tgcctttcaa gattgtcatt ccacctgctt cctatacttt ggggagccac atcgctattt
      241 ttatagccat gttcttgtcg cccttgatgg cagtttttgt catcctagcc tctagttttg
      301 gatttttgat ggctggctat cccatggtta tcgtttttcg ggctttttcc catatatctt
      361 ttggtgcttt aggagctctt tacctacaaa aattccccga taccctagat aaaccaaaat
      421 cttcctgggt tttcaatttt gttttggctg ttgttcatgc ccttgctgaa gtattagcct
      481 gtgtcctttt ttacgcaact tcgggtacca atgtagaaaa catgttctat gttctatttg
      541 tactagttgg atttggcaca attatccata gtatggtaga ctatacatta gcactagctg
      601 tctataaagt gcttcgaaaa cgccgttaaa aggaaaagct atgacaaaag atcgcaaaca
      661 agccctgctc caactcttga aagaagctcc taaagccctt aatggccaaa gtttggcgga
      721 acattttcat gtcacacgtc aggtcattgt gcaggacatt gcaattttga gagccgatgg
      781 cgctcctatc ctatccacca atcgtggcta catctataag caaattgata ccaatcctta
      841 tgttcacaaa cttttcaaag tgaaacatga agttgaagaa atcggtcagg aactccttgc
      901 tattgtcgat aatggtgggc atgtccagaa taccttgatt gaccatcccg tttatggaga
      961 aattgaaacc ttgcttaaac tgtcttgtcg cagagatgtg caacattttc tagaacaagt
     1021 cgagcattct gactttagac ctctatctga attgacagat ggcatccatt accacctagt
     1081 cgaagccgaa acacaacaag acctccacta tatcgaggag gccttggatc agctaggtta
     1141 tttagtaaaa gactagaaga ttttcttttc ccaatcgtct tctgtacggc gaggatagaa
     1201 aaactctgac ttgtcgggag ctaccatcat ttccatcaat ggtagcatat catagaag
//
LOCUS       DAVHSI010000101         1032 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.126, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000101 DAVHSI010000000
VERSION     DAVHSI010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.126"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            complement(<1..1021)
                     /gene="celB"
                     /locus_tag="VVR21_002124"
     CDS             complement(<1..1021)
                     /gene="celB"
                     /locus_tag="VVR21_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU6055895.1"
                     /translation="MFGFLENHVMGPMGKLAQFKVVRAITVAGMAAVPFTIVGSMFLV
                     FSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYELTKIYAE
                     EEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMGNGVARF
                     GTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVVAFVVIF
                     INGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGANIVFAFV
                     SPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQLKAIGRA
                     SVVPAL"
BASE COUNT          378 a          226 c          169 g          259 t
ORIGIN      
        1 ataaggctgg aactacagat gctcgtccta ttgctttaag ctgttcagat ttagaggcaa
       61 aagcaatata taaacatagt cctaaagttg caccagaacc acctgcaatt acaaacatat
      121 tagaaaattc acctgcaaca gcgaagtgcc cgccagcagc attttcagcc atgttagcaa
      181 gagcaattgg actaacaaat gcaaaaacaa tgttcgcacc gtggatacct acaatccaaa
      241 gtagttgagt caatagataa ataatcatta aaccaatcca cgaattagtc agattggata
      301 caaaaccaaa tggaattgca atgactttaa aaatatctgt tcccattgct acaagaagac
      361 cgttgataaa gataacaaca aatgcaacaa caaatcccgg aaccaaagcg gtaaatccac
      421 gagaaactcc ttctggaaca gcttcaggca ttttaataac ccaattatgt ttaacacaca
      481 tacgataaat aagaacagtc acaattgcca taatgattgc ggtaaaaatc cctgttgtcc
      541 caaaacgtgc gactccattt cccattgccc atccatctgc aattactgca ccttctttta
      601 gacttgtcac agtcttcatc attccaccat caaaaatgat ttgcggtact gtcatgacaa
      661 aagccatcaa ggcaagcaag gcaccattaa gaggattcat attgagttct tcttcctctg
      721 cataaatttt tgtcaattca tatgcaagtg atagaacgaa ataaagagat agagaaccca
      781 tagtcgcata gtttgcaacc atgtaaagtg atgtgaattt atcaaatgaa gcagagaaaa
      841 tatctgccac aattggccaa aatgagaaag cttgtggcaa aatactgaat accaaaaaca
      901 ttgatcctac aatagtaaat ggtacagcag ccatacctgc aaccgtgata gcacgtacta
      961 ctttaaactg agcaagtttg cccattggtc ccataacatg gttttcaaga aaaccaaaca
     1021 acccgttttg tt
//
LOCUS       DAVHSI010000102          856 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.134, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000102 DAVHSI010000000
VERSION     DAVHSI010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..856
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.134"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..>856
                     /locus_tag="VVR21_002125"
     CDS             <1..>856
                     /locus_tag="VVR21_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU6055896.1"
                     /translation="GLHQAQTVKENNRVSYIDGKQATQKTENLTPDEVSKREGINAEQ
                     IVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDSDIVNEIKGGYV
                     IKVNGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTSANDGAVALARSQGRYT
                     TDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELAAAEAFLSGRENLSNLR
                     TYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSNTNSQASQSNDIDSLLKQLYKLPLS
                     QRHVESDGL"
BASE COUNT          296 a          176 c          179 g          205 t
ORIGIN      
        1 aggtttgcat caagctcaaa ctgtaaaaga aaataatcgt gtttcctata tagatggaaa
       61 acaagcgacg caaaaaacgg agaatttgac tcctgatgag gttagcaagc gtgaaggaat
      121 caacgccgaa caaatcgtca tcaagattac ggatcaaggt tatgtgacct ctcatggaga
      181 ccattatcat tactataatg gcaaggtccc ttatgatgcc atcatcagtg aagagctcct
      241 catgaaagat ccgaattatc agttgaagga ttcagacatt gtcaatgaaa tcaagggtgg
      301 ttatgtcatt aaggtaaacg gtaaatacta tgtttacctt aaggatgcag ctcatgcgga
      361 taatgtccgt acaaaagaag aaatcaatcg gcaaaaacaa gaacatagtc agcatcgtga
      421 aggagggact tcagcaaacg atggtgcggt agccttggca cgttcacagg gacgctacac
      481 cacagatgat ggttatatct tcaatgcatc tgatatcatc gaagatacgg gcgatgccta
      541 tatcgttcct catggagatc attaccatta cattcctaag aatgagttat cagctagcga
      601 gttggctgct gcagaagcct tcctatctgg tcgggaaaat ctgtcaaatt taagaaccta
      661 tcgccgacaa aatagcgata acactccaag aacaaactgg gtaccttctg taagcaatcc
      721 aggaactaca aatactaaca caagcaacaa cagcaacact aacagtcaag caagtcaaag
      781 taatgacatt gatagtctct tgaaacagct ctacaaactg cctttgagtc aacgacatgt
      841 agaatctgat ggcctt
//
LOCUS       DAVHSI010000103          851 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.135, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000103 DAVHSI010000000
VERSION     DAVHSI010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.135"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            <1..>851
                     /gene="phtB"
                     /locus_tag="VVR21_002126"
     CDS             <1..>851
                     /gene="phtB"
                     /locus_tag="VVR21_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU6055897.1"
                     /translation="SRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHWV
                     PDSRPEEPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVS
                     RYIPAKDLSAETAAGIDSKLAKQESLSHKLGTKKTDLPSSDREFYNKAYDLLARIHQD
                     LLDNKGRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAPIRHPERLGKPNAQITYT
                     DDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAA
                     QAYAKEK"
BASE COUNT          277 a          183 c          180 g          211 t
ORIGIN      
        1 caagtcgaac cgccagaggt gtagctgtcc ctcatggtaa ccattaccac tttatccctt
       61 atgaacaaat gtctgaattg gaaaaacgaa ttgctcgtat tattcccctt cgttatcgtt
      121 caaaccattg ggtaccagat tcaagaccag aagaaccaag tccacaaccg actccggaac
      181 ctagtccaag tccgcaacct gcaccaaatc ctcaaccagc tccaagcaat ccaattgatg
      241 agaaattggt caaagaagct gttcgaaaag taggcgatgg ttatgtcttt gaggagaatg
      301 gagtttctcg ttatatccca gccaaggatc tttcagcaga aacagcagca ggcattgata
      361 gcaaactggc caagcaggaa agtttatctc ataagctagg aactaagaaa actgacctcc
      421 catctagtga tcgagaattt tacaataagg cttatgactt actagcaaga attcaccaag
      481 atttacttga taataaaggt cgacaagttg attttgaggc tttggataac ctgttggaac
      541 gactcaagga tgtctcaagt gataaagtca agttagtgga agatattctt gccttcttag
      601 ctccgattcg tcatccagaa cgtttaggaa aaccaaatgc gcaaattacc tacactgatg
      661 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
      721 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      781 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      841 ctaaagagaa a
//
LOCUS       DAVHSI010000104          830 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.137, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000104 DAVHSI010000000
VERSION     DAVHSI010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.137"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            21..830
                     /locus_tag="VVR21_002127"
                     /pseudo
     CDS             21..830
                     /locus_tag="VVR21_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVHSI010000105          792 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.138, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000105 DAVHSI010000000
VERSION     DAVHSI010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.138"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            173..649
                     /locus_tag="VVR21_002128"
     CDS             173..649
                     /locus_tag="VVR21_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU6055898.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            687..>792
                     /locus_tag="VVR21_002129"
     CDS             687..>792
                     /locus_tag="VVR21_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU6055899.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHC"
BASE COUNT          289 a          120 c          143 g          240 t
ORIGIN      
        1 agaacagaaa aaatgcttgg agtatttgtt tgtgtgttta tttttatata acaaactata
       61 aacaaaacaa aaatataaaa aaagagacaa aaaagaacag aaagtaattg acaacggttt
      121 catatagtgt tatacttatg gcataaagtt aatggaaaga agggaaaaac ttatggtatt
      181 agattatttc tttgacaaaa accttgtgtt ttgcttagaa gcggataatc aagaacaact
      241 ctttgatcag gttgcaactt tattggaaga acgagaaatt gtcactccaa cttatcgtga
      301 agccttgatc acgcgtgaaa agtcatttcc aactggttta gatatggaat ttctaggaaa
      361 ggacttgcca aatgtagcga ttcctcatac agatattgtt cataatctag ctgagaaagt
      421 ggtggttgtt cgattagaaa aaccagtaac ttttcacaat atgatagctc ctgataagga
      481 agtagaagta tccctactct tctttattat taacaattca agttcaagtc aaacaaatat
      541 tctggctcag ttgatggact ttttcacagg aaatggacat cttgaagatt tatcaaaaat
      601 ttccgaacca gaaaaacttt atgcttacat tgctgaagca accgcttaat cttgtctatt
      661 aaaaaataaa atcggaggaa atccaaatga ttaaaattct tgctgcctgc ggtgcaggtg
      721 ttaactcaag tcaccaaatt aaaagtgctc tagaagaaga actttcaaac cgtggttatg
      781 atgttcactg tg
//
LOCUS       DAVHSI010000106          634 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.denovo.149, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000106 DAVHSI010000000
VERSION     DAVHSI010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.denovo.149"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            1..634
                     /locus_tag="VVR21_002130"
                     /pseudo
     CDS             1..634
                     /locus_tag="VVR21_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          190 a          135 c          111 g          198 t
ORIGIN      
        1 tgttcaaaaa tgatggttgc tgagactccc ctggtaaaga aaaatcacca aatccctcgt
       61 atcatcaacc aaaaaattgc tcaaaagtta attgaaaaaa tttctatgac tgatattgcc
      121 catcagcttt ccatttcaac ttcaactgtc attcgcaagc tcaatgactt tcactttgag
      181 catgattttt ctcggcttcc aaagattatg tcttgggatg agtatgcctt cactaaggga
      241 aagatgagtt tcattgcgca agattttgat aatcttaata ttatcactgt tcttgaaggc
      301 agaacacaag ctgtcatccg aaatcacttt cttcgctacg atagagccgt tcgttgtcaa
      361 gtgaaaatca ttacgatgga tatgtttagt ccttactatg acttggctaa acagcttcgc
      421 tttcaaattt ctaggctcag gctgaaacag tctcccagac tgtttcactc ccgaatgcta
      481 aaatcgttct tgatcgcttt cacattgtac aacatcttag ccgtgctatg agtcgtgtgc
      541 gtgttcaaat tatgaatcag tttgaacgaa aatctcatga atacaaggct atcaagcgtt
      601 actggaaact catccaacag gatagtcgta aact
//
LOCUS       DAVHSI010000107        17123 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain Streptococcus species
            isolate Cambodian child SAMN04254707-rid19264853.guided.041, whole
            genome shotgun sequence.
ACCESSION   DAVHSI010000107 DAVHSI010000000
VERSION     DAVHSI010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04254707
            Sequence Read Archive: SRR2912552
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001866617.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001866617.1
            Genome Coverage       :: 313x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/29/2023 02:26:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,149
            CDSs (total)                      :: 2,103
            Genes (coding)                    :: 1,941
            CDSs (with protein)               :: 1,941
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 68 of 162
            Pseudo Genes (incomplete)         :: 79 of 162
            Pseudo Genes (internal stop)      :: 52 of 162
            Pseudo Genes (multiple problems)  :: 31 of 162
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04254707-rid19264853.guided.041"
                     /strain="Streptococcus species"
                     /serotype="5"
                     /isolate="Cambodian child"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Cambodia"
                     /lat_lon="13.21 N 103.51 E"
                     /collection_date="2011-06-14"
                     /collected_by="Catrin Moore"
     gene            82..669
                     /locus_tag="VVR21_002131"
     CDS             82..669
                     /locus_tag="VVR21_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU6055900.1"
                     /translation="MSKRLEVKDLINIGLFSVLGFVFMMIGSFLGMVPVLMPVVPFAQ
                     GVLVGPVNMLYSTKIKKRGMVFIQSLLIALVYVAMGHGPWALLTAVIAGIIAEVILKS
                     GEYTDVNKARLAFSVAPLCTLGNWLPIFISRNEYVKQMLERGYKQEFIDKMLSVMPNW
                     IIVVMAIGGIIGAYIGCSIGMAFLKKHFKKAGMEK"
     gene            690..1391
                     /locus_tag="VVR21_002132"
     CDS             690..1391
                     /locus_tag="VVR21_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU6055901.1"
                     /translation="MTIKLDFRTKLFMTIVLSYVMVLGNIQVKYFLQALIISVIPIVL
                     LINTKHTRVAIIGMATLVFVYGADRFLMKLEYSPLVAILLILVMVVKKILPAFLMGKY
                     TILTSNVGESIYSLKKMKCPDEIAIPLTVMVRFFYAARIDYSQIKKAMRLRGLTLKKL
                     IKNPILLFEYRLVPLLMCLSKTADDLTVSAMTKGLAVNQKRTSISESRIGGIDCIFFV
                     IMVWAIYLYIRGKYA"
     gene            1384..1941
                     /locus_tag="VVR21_002133"
                     /pseudo
     CDS             1384..1941
                     /locus_tag="VVR21_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844950.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            2274..2588
                     /locus_tag="VVR21_002134"
     CDS             2274..2588
                     /locus_tag="VVR21_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6055902.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            2604..2990
                     /locus_tag="VVR21_002135"
     CDS             2604..2990
                     /locus_tag="VVR21_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEU6055903.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            3019..4404
                     /locus_tag="VVR21_002136"
     CDS             3019..4404
                     /locus_tag="VVR21_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU6055904.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            4407..4559
                     /locus_tag="VVR21_002137"
     CDS             4407..4559
                     /locus_tag="VVR21_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6055905.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            4582..5787
                     /locus_tag="VVR21_002138"
     CDS             4582..5787
                     /locus_tag="VVR21_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEU6055906.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            5830..6051
                     /locus_tag="VVR21_002139"
     CDS             5830..6051
                     /locus_tag="VVR21_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU6055907.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            6168..6665
                     /locus_tag="VVR21_002140"
     CDS             6168..6665
                     /locus_tag="VVR21_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEU6055908.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            6640..7146
                     /locus_tag="VVR21_002141"
     CDS             6640..7146
                     /locus_tag="VVR21_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6055909.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            7130..9577
                     /locus_tag="VVR21_002142"
     CDS             7130..9577
                     /locus_tag="VVR21_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU6055910.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            9580..11757
                     /locus_tag="VVR21_002143"
     CDS             9580..11757
                     /locus_tag="VVR21_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU6055911.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYDPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            11754..12755
                     /locus_tag="VVR21_002144"
     CDS             11754..12755
                     /locus_tag="VVR21_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEU6055912.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            12752..13684
                     /locus_tag="VVR21_002145"
     CDS             12752..13684
                     /locus_tag="VVR21_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEU6055913.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            13929..14045
                     /locus_tag="VVR21_002146"
     CDS             13929..14045
                     /locus_tag="VVR21_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEU6055914.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            14061..15980
                     /gene="tet(M)"
                     /locus_tag="VVR21_002147"
     CDS             14061..15980
                     /gene="tet(M)"
                     /locus_tag="VVR21_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEU6055915.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDYLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            16099..16266
                     /locus_tag="VVR21_002148"
     CDS             16099..16266
                     /locus_tag="VVR21_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEU6055916.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(16326..16679)
                     /locus_tag="VVR21_002149"
     CDS             complement(16326..16679)
                     /locus_tag="VVR21_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU6055917.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
BASE COUNT         5582 a         2969 c         3546 g         5026 t
ORIGIN      
        1 tttttcacaa cataaaaaat atataaaaga aacaatggta aattacattg ttgatattga
       61 caagagatag ggaggtttaa aatgagtaaa cgattagaag taaaggattt aatcaacata
      121 ggattatttt ctgtattagg ttttgtattt atgatgattg gatcattttt aggaatggtt
      181 ccagttttaa tgccggttgt tccatttgca cagggagttt tagtaggacc tgtaaatatg
      241 ctgtattcca caaagattaa aaaaagagga atggtgttta ttcaatcatt acttattgca
      301 ttagtatatg ttgctatggg acatggacct tgggcattat tgaccgctgt tattgctggt
      361 attattgctg aagttatttt gaaatcagga gaatatacgg atgttaataa ggcaagatta
      421 gcattttctg ttgctccact ttgcacatta ggaaattggt tgccaatttt tatatcaaga
      481 aatgaatatg tcaagcagat gttagagcga ggatataaac aagaatttat tgataagatg
      541 cttagtgtaa tgccgaattg gattattgtc gtaatggcaa taggtggaat tataggagca
      601 tatattggtt gtagtatagg tatggctttc ctaaaaaaac attttaaaaa ggctggtatg
      661 gaaaaataag gattcataag gagttaagga tgacaatcaa acttgatttt cgtacaaaac
      721 tttttatgac aatagttctt tcatatgtga tggttttagg caatattcaa gtaaagtatt
      781 tcttgcaagc ccttataata tccgtaattc cgatagtgct tttaataaat acaaaacata
      841 caagagtagc tattattggg atggctactc ttgtgttcgt ttatggtgct gatagatttt
      901 taatgaaatt agaatacagt cccttggtag cgattttact gatattagta atggttgtta
      961 agaaaatact tcccgcattt ttaatgggga aatataccat actcacatca aatgtagggg
     1021 aaagtattta ttcattgaaa aaaatgaaat gtcccgatga aatagcaata ccattgactg
     1081 tgatggttcg tttcttttat gccgcaagga ttgattatag ccagataaaa aaagccatgc
     1141 gtttgagagg actaacgctt aaaaagttaa taaaaaatcc aattctatta tttgaatata
     1201 gattagtgcc actattgatg tgtttgtcta agacggcaga tgatttaaca gtatccgcaa
     1261 tgacaaaagg gttagctgtt aatcaaaagc gaacaagtat tagtgaatca cgcattggtg
     1321 gcattgattg catatttttt gtgataatgg tatgggcaat ctatttatat ataaggggta
     1381 agtatgctta gtttacaaaa tttagtatta aagtttgatg gagaaagcat attagaaaat
     1441 gtaaatctaa atttcaaacc cggagaggta actgttataa cgggacactc aggtacgggg
     1501 aaaagtagtt tgttaaaagt aataaacggc attattcccg aatatgattg tggagatgta
     1561 aaaggagatg ttttatacaa ggacaaatct ttattaggga tgagtatatt agaacgatcc
     1621 aagtttatat ctacagtgtt tcaaaatcct aaaacacagt tttattgtat caattccaca
     1681 gatgaattgg cttttcaatt agaaaataga tgtatagaaa gaaatttaat tttagataaa
     1741 atacactatt attcagatgt tttaggtagt aaagatttgt tagacaagaa tatttttgaa
     1801 ctgtccggtg gagagaagca gttaattgct ataactgcta gtggaatttc agaaaatgaa
     1861 attattcttt tagatgaacc atcttcatct ttggattatg aatcaattaa gaacttaaaa
     1921 agagctatta ttgagctaaa aatagcataa aaatctagtt atccgcataa aaactggact
     1981 tatcacactt tatcaaggtc aaaaccactc aatttactac taatttacta cttatgaatg
     2041 agctttgata cgacgattta tccttgaaaa gtgaagatat aaagatactt ccaataaaat
     2101 ttgaatattt aataggtaga cacttcaaaa aatgaggtgt ctattttttt acccgatttt
     2161 gaaaggaagt gaacttatga aaacaaaaaa tcaagaatca aaaggtcgtt ccccactctt
     2221 taagaccatc aaacattcat tcagccaata aaaaagaaag gataggtaaa aatatggaac
     2281 ttaaatttgt gattcccaac atggaaaaaa cattcggcaa tttagaattt gctggcgagg
     2341 ataaagtcgt tcagcgaaga atcaacggac ggctaactgt cttatcaaga agctataatc
     2401 tctattctga tgttcaaaga gcagatgata ttgtggtggt gcttcctgct gaagctggcg
     2461 aaaaacattt cggctttgag gaacgtgtga agttagtcaa tccacgtatt accgcagagg
     2521 gctacaaaat cggcactcgt ggttttacaa attacctttt acatgctgac gacatgataa
     2581 aagaataaag aaagagagga aaaatgatga gattagcaaa tggcattgta ttagataaag
     2641 acacgacttt tggagaattg aaattctctg ctctacgtcg tgaagtgaga atccaaaatg
     2701 aagacgggtc ggtttcagat gaaatcaagg aacgtaccta tgacttaaaa tccaaaggac
     2761 aaggacgcat gattcaagta agtattcctg ccagcgtgcc tttgaaagag tttgattata
     2821 acgcacgggt ggaacttatc aatcccattg cggacaccgt tgctactgcc acctatcaag
     2881 gagcagatgt tgactggtat atcaaggcag acgatattgt gctgacaaag gattctagtt
     2941 cattcaaagc tcaaccacaa gcaaagaaag aaccgacaca agacaaatag tcgctaggta
     3001 gaaaggagac tttttcgcat gaaacagcgt ggtaaaagga ttcgcccatc tggtaaagat
     3061 ttagtctttc attttacgat agcgtcactc ctgcctgttt tcctgctggt tgtcggactg
     3121 tttcatgtga agacaatcca gcagatcaac tggcaggatt ttaacctatc acaagcagat
     3181 aagattgaca ttccctattt aattatcagt ttcagtgtcg caattcttat ctgcttgctg
     3241 gtagcgtttg tattcaaacg ggttcgctat gatacggtta aacaacttta ccaccgtcaa
     3301 aaactggcaa agatgatact tgaaaacaag tggtatgaat ctgaacaggt caaaacagag
     3361 ggtttcttta aagatagtgc tggtcgtaca aaggaaaaga taacctactt ccctaaaatg
     3421 tattatcgac ttaaaaatgg cttgatacag atacgggtgg aaatcacgct gggaaaatat
     3481 caagaccaac tcttacactt ggaaaagaaa ttagagagtg gcttgtactg tgagctgacg
     3541 gataaagagt taaaggattc ctatgtggaa tatactttgc tctatgacac catagccagt
     3601 cgtatttcta ttgatgaagt agaagctaaa gatggtaaac ttcgcttaat gaaaaacgta
     3661 tggtgggaat atgataagct ccctcatatg ttgattgctg gtggtacagg tggcggtaaa
     3721 acttacttta tactgacact gattgaagcc ttgcttcata cagattcaaa actgtatatt
     3781 cttgacccga aaaatgctga tcttgcggac ttaggttctg tgatggcaaa tgtctactat
     3841 agaaaagaag acttgctttc ttgcattgaa acattctatg aagaaatgat gaaacgtagt
     3901 gaggaaatga agcagatgaa gaactataag actggcaaaa attatgctta cttaggtctc
     3961 ccggcacact tcttaatctt tgatgaatac gtcgctttca tggaaatgct gggaacaaaa
     4021 gaaaacaccg cagttatgaa taagctgaaa cagattgtca tgttaggtcg tcaagctggc
     4081 ttctttctaa tactggcttg tcaacgtcca gacgcaaaat atttaggcga cggaatccgt
     4141 gatcagttta atttcagagt ggctttaggt cgtatgtctg aaatgggcta tggcatgatg
     4201 tttggcagtg acgtacaaaa ggatttcttc ttaaagcgaa tcaaaggtcg tggctatgtt
     4261 gatgtaggaa caagtgtcat atcagagttt tatactcccc ttgtaccaaa aggatatgat
     4321 ttcttggagg aaattaaaaa gttatccaac agcagacagt ccacgcaggc gacgtgcgaa
     4381 gcggaagtcg caggtgtgga ctgatcttgc tggctggtgt ggcaatagcc acgccagcac
     4441 ttaacccccc gtatctaaca ggggggtaca aatcgacagg aaacagtcaa aaaaacatta
     4501 gaaaatcctt tggttacaag ggatttacaa aatttcagcg tatgtcaaat gggctttaaa
     4561 agttgacata cgcctttttg attggaggga tttttactga atgaacaaac ttggttacag
     4621 catttaaaag aaaaacgctt ggcttatgga ctatctcaaa accgtttagc tgttgcgact
     4681 ggtattacaa ggcagtatct aagcgatatt gaaacaggaa aagtcaagcc atcagaggat
     4741 ttacagcagt ccctttggga agctctggaa cgcttcaatc ccgacgctcc ccttgaaatg
     4801 ctgtttgatt atgtaagaat tcgctttccg acaacagacg tacagcaggt ggtcgaaaac
     4861 atcttacaac tgaaactgtc ctattttctt catgaggact atggtttcta ttcttattca
     4921 gagcattatg ctttaggcga catattcgtc ctttgctccc atgaactgga caaaggagtt
     4981 ctggtggaat tgaaaggtcg tgggtgcaga caatttgaaa gctatcttct ggcacaacaa
     5041 agaagctggt atgagttctt tatggacgtt ttggtggctg gcggtgtgat gaaacgcctt
     5101 gaccttgcca ttaacgataa gacagggatt ttaaatatcc ctgtactcac tgaaaagtgc
     5161 caacaggaag aatgtatctc cgtcttccgc agttttaaaa gctatcgcag tggcgaactg
     5221 gtacgcaaag aggaaaagga atgtatggga aacaccctct atatcggttc attacaaagt
     5281 gaagtttatt tctgtatcta tgaaaaggac tacgagcagt acaagaaaaa tgatattccc
     5341 attgaagacg cagaagtaaa aaaccgtttt gagattcgat tgaaaaatga gcgtgcctat
     5401 tatgcagtcc gtgatttact cgtctatgac aatccagagc ataccgcctt taaaattatc
     5461 aatcggtata tccgttttgt agataaagac gattccaaac ctcgttctga ttggaaactg
     5521 aatgaagaat gggcttggtt tattgggaac aatcgtgaac gattaaaact aaccacaaaa
     5581 ccagagcctt actccttcca aaggacgctg aactggctat ctcatcaagt tgccccgacc
     5641 ttaaaggttg cgattaaact tgatgaaatc aaccagacgc aggttgtaaa agacattctc
     5701 gaccatgcga aactgacaga ccgacacaag cagattttga agcaacagtc agtaaaagaa
     5761 caggacgtga taacaacaaa aaaataactc aaatacaaat tcattgaata tagagaggag
     5821 aacattttta tgaattttgg acaaaacctt tataactggt ttctatcaaa cgctcaatca
     5881 ctggtgcttt tagcaatcgt tgtgattggc ttgtatcttg gcttcaagcg tgagtttagc
     5941 aaactgattg gctttttaat tattgcgatt attgcggttg gcttagtctt caacgctgct
     6001 ggagtaaaag acattttact agagctattc aatcgcatta ttggtgctta aataaaaccg
     6061 ttcttttgtg gaatataagt ggttttctta tgttccgcaa aggaatggta caccaaacga
     6121 agtgcggtag ggatttttga atctctacaa agaaaggacg tgaatatatg gacgatatgc
     6181 aagtctatat tgcgaattta ggcaaataca atgagggcga attggtcggt gcgtggttta
     6241 cctttcccat tgactttgag gaagtcaaag agaaaatcgg cttgaatgat gaatatgagg
     6301 aatacgccat tcatgactac gagttaccct ttacggttga cgaatacact tccattggcg
     6361 aactcaatcg actatgggaa atggtatcgg aattacccga agaattacaa tcggagctat
     6421 ctgctctgct cactcatttt tcaagcattg aagaactaag cgaacatcaa gaggatatta
     6481 tcattcattc cgattgtgat gatatgtatg acgtggcacg ctactacatt gaagaaacgg
     6541 gtgctttagg cgaagtacca gctagtcttc aaaactatat tgattatcaa gcctatggtc
     6601 gggatttaga cctttcagga acgtttatct caaccaatca tgggattttt gaaatcgtct
     6661 attaaatctg tcggtacatt actactggca gattttctat tttacggggt ggctcaatca
     6721 gctaccccta ttttttatga aaggattgat tacatgaaga aaatacgaag ctataccagt
     6781 atctggtctg tggaaaaggt actgtattct atcaatgatt ttagacttcc gtttcccata
     6841 acctttacgc aaatgacatg gtttgtcgtg tcactctttg cagtgatgat acttggcaac
     6901 ttgccccctc tttccatgat agagggagca tttctcaaat actttgggat tcctgtggct
     6961 ttcacatggt ttatgtctac aaaaactttt gatggtaaaa agccttatgg atttttgaag
     7021 tctgtcattg cttatgcact gcgaccaaag ctgacctatg caggaaaaaa agtaacgctt
     7081 ggcagaaacc agccacaaga agccattaca gcagttagga gtgaatttta tggcatatcc
     7141 aattaaatac attgaaaaca atctcgtctg gaataaagac ggggaatgtt atgcttacta
     7201 tgagcttgtt ccttacaatt actcatttct aagtccagaa cagaaaatac aagtgcatga
     7261 ttctttcaga cagcttatcg cacaaaatcg tgatggcaaa attcatgctt tacaaatcag
     7321 tacagaatcc agcatacgtt ctgcacaaga gcgttccaaa aatgaagtca ctggcaagct
     7381 caaagcggtt gcctatgaca aaatcgacca acagacagac gctttaatat ccatgattgg
     7441 cgaaaatcaa gtgaactacc gtttctttat cggctttaag ttgcttctca acgatcagga
     7501 gttttctatg aaaagtctta ccgttgaagc aaaaaatgct ttgtctgatt ttgtctatga
     7561 tgtgaaccat aagctgatgg gcgattttgt tagtatgagt aatgatgaaa tcctgcgttt
     7621 tcagaagatg gaaaagctct tagaaaataa aatctctcgt cgtttcaaaa tccgcaggtt
     7681 agataaggac gacttcggct atctgattga acacctttac ggacagacag gcactgccta
     7741 tgaagagtat gagtaccatc tatcaaagaa aaagctggat aatgaaacgc tgattaaata
     7801 ctatgacttg attaagccta ctcgctgttt ggtggaagaa aaacagcgat atttgaaaat
     7861 ccagcaggaa gatgaaaccg tctatgtagc ttactttacc attaacagca ttgtcggaga
     7921 actggacttc ccgtcctctg aaatcttcta ctaccagcaa cagcaattta cattcccgat
     7981 tgatacgtca atgaatgtgg aaattgtagc gaatcgtaaa gccctatcta ctgtccgcaa
     8041 taaaaagaaa gaactgaaag acttggataa ccacgcttgg caaagtgata atgaaaccag
     8101 ctccaatgtg gcggaagctc tggaaagtgt gaatgagctg gaaaccaatt tagaccaaag
     8161 caaggaatct atgtacaagc tgtcttatgt ggtaagggta tcagcaaatg atcttgacga
     8221 actcaaacgt cgttgtaatg aagtgaaaga tttttatgac gatttaagcg taaaactggt
     8281 acgaccattt ggggatatgc tcggcttaca tgaagaattt ttacctgcca gcaagcgtta
     8341 tatgaatgat tatattcaat acgtgacctc tgatttcctc gctggtttag gttttggtgc
     8401 tactcaaatg ctgggggaaa atgaggggat ttatgttggc tacagcttag atactggacg
     8461 caatgtctat ctgaaacctg ctcttgccag tcaaggggtt aagggttcag taaccaatgc
     8521 gttagcgtcg gcttttgttg gttcgctggg tggtggtaaa tcctttgcga ataaccttat
     8581 cgtctattat gcggtgcttt atggggcaca agcagtgatt gtagacccaa aagcagaacg
     8641 tggcagatgg aaagaaacct tgccagagat ttcccatgaa atcaatatcg tcactctgac
     8701 ttctgatgag aaaaacaaag gcttacttga cccttatgtg attatgaaaa atcccaaaga
     8761 ttctgaatca ctggctattg atattctgac attccttacg gggatttcct ctcgtgatgg
     8821 ggaacgcttc ccaatcctta gaaaagccat tcgtgcagta accaatagtg aagtacgagg
     8881 gttgatgaaa gtgattgagg aattacgggt tgagaatacg ccactaagta ccagtatagc
     8941 cgaccatatc gaaagtttta cagactatga ctttgcacat ttattattca gtaatggtta
     9001 tgtggagcag tctatcagct tagaaaaaca actgaacatt atacaggttg cggacttggt
     9061 acttcccgac aaggaaactt cctttgagga atataccact atggagcttt tatccgttgc
     9121 tatgctgatt gtcattagta cctttgcttt agactttatc catacagacc gaagcatttt
     9181 caagattgta gatttagacg aagcatggag ctttttacag gtagcacaag gaaaaacact
     9241 atctatgaag ctggttcggg ctggtcgtgc tatgaacgct ggggtatatt tcgtgaccca
     9301 aaatacagac gacctcttag atgaaaaact gaaaaataac ctcggcttaa aatttgcatt
     9361 tcgttccact gaccttaacg agattaaaaa gaccttagcc ttttttggtg tagacccaga
     9421 ggacgaaaac aatcagaagc gattgcgtga tttggaaaac gggcaatgcc ttatcagtga
     9481 tttatatggt cgtgtcggtg tgatacagtt ccaccctgta tttgaagaac tgctccatgc
     9541 ctttgatacc agaccacctg tgcgaaaaga ggtgtaaatg tgaaaccatc aatagtaaac
     9601 agaataaaat caaactggac gctgaaacgt ctaggtaaag tggcaatgac agtggctttc
     9661 acacttgtga ttgccatttt tcttttagcc atgctgggaa cggtggttca agctgcgggc
     9721 ttggtagatg atacggtcaa tgtggcaaat gaatacagcc gatacccact tgaaaactat
     9781 caactggatt tttatgtgga taatagctgg ggctggcttc cgtggaactg gtcggacggg
     9841 attggaaaac aggtcatgta tggactatat gccattacca attttatttg gacaatcagt
     9901 ttgtatgttt ccaatgcgac aggttactta gtacaggaag cctattcctt agacttcatt
     9961 tccgctacag cagattccat tggtaagaat atgcagacct tagctggtgt gagtgcaaac
    10021 ggattttcaa cagagggttt ctatgttgga ttcctcttac tcttgatttt ggttcttggg
    10081 gtttatgttg cctatacggg actgataaag agagaaacca caaaggcaat tcatgccatt
    10141 atgaattttg tgctggtgtt tatcctatcg gcttccttta ttgcctacga tcccgactac
    10201 attaaaaaaa tcaatgactt ttcatcagac atcagtaatg ccagtttatc acttggcacg
    10261 aagattgtca tgccccattc cgatagtcaa ggcaaggaca gcgtggactt aatcagagat
    10321 agcctgtttt ccatacaggt tcagcaaccg tggctactgc ttcaatacaa cagttcagac
    10381 attgaaagta tcggtattga ccgtgtggaa agcctgctct ccaccagccc agattccaac
    10441 aatggcgaag atagagaaaa aattgttgcg gaagaaattg aagacagaag caataccaat
    10501 ctaaccatta caaagaccat taaccgttta ggtacagtct tcttcctatt tgtcttcaat
    10561 attgggattt ccatatttgt attcctatta acaggaatca tgattttctc gcaggtactt
    10621 tttatcatct atgctatgtt tctgcctgtg agctttattt taagcatgat tccatcattt
    10681 gatggtatgt caaaacgagc cataacaaag ctctttaata ccattttgac acgagctgga
    10741 atcacattga ttattacgac agcatttagt atttcaacca tgctctatac cttatcggct
    10801 ggttatccgt tctttttgat tgcttttcta cagattgtga cctttgcagg aatctacttc
    10861 aagctgggcg atttaatgag tatgttttct ctacagagta acgattctca aagtgtggga
    10921 agtcgtgtga tgagaaaacc tcgtatgctt atgcacgctc acatgcaccg tctacagcgg
    10981 aaacttggac gttccatgac tactctaggg gctgggtctg ccattgttac aggtaaaaaa
    11041 ggacagtcgg gttcggggag ttctgcaagg acacaagcag atcactcccg accagacgga
    11101 aaggaaaaat caacacttgg aaaacgtatc ggtcaaacca tcggtacagt agctgatacc
    11161 aaagacagaa tggtagacac tgctagtggt ttgaaagaac aggttaaaga tttgccgacc
    11221 aatgcaagat atgcagtata tcaaggaaaa tccaaagtaa aagagaatgt ccgtgattta
    11281 accagtagta tttctcaaac caaagcggac agagccagtg gacgcaagga acagcaggaa
    11341 caaaggcgaa aaaccattgc gaagcgtcgc tctgaaatgg aacaggtcaa acagaaaaaa
    11401 cagcctgctt cttctgttca tgaaagaccg actacaagac aagaacaata tcatgatgaa
    11461 cagacctcaa aacagtctaa tattcagact tcatataagg aatctcaaca agccaaacaa
    11521 gagcgtccag cagttaagtc cgatttttca agtccaaaag tggaacgcca aggcaatacc
    11581 gttcaagaaa aaaccgttca aaagccagca acttcaacca ctacagcaga tagaacttca
    11641 caacgtccaa tcacaaaaga acgtccgtct actgttcaaa gagtaccact acaaaataca
    11701 agaagtagac caccaatcaa aaccgccacc attaagaaag tcggtaagaa accatgaagt
    11761 tgaaaacttt agtgattggt ggttctggat tattcttgat ggtcttctca ctgcttctgt
    11821 ttgttgccat tttattttca gatgaacagg acagcggaat ttccaatatt cattatggag
    11881 gtgtgaatgt ttccgcagaa gtgctggctc ataagcctat ggtagaaaaa tatgccaaag
    11941 aatatggcgt tgaagaatat gtcaacatac ttcttgcgat tatacaggtg gaatcgggcg
    12001 gtactgcgga agatgttatg cagtcctcgg aatccctcgg tcttccacct aattcattga
    12061 gtacagaaga atccattaag caaggtgtga agtatttcag tgaattatta gccagtagcg
    12121 aaaggctcag tgtagattta gaatcggtta tccagtccta caattatggt ggtggtttct
    12181 tagggtatgt ggctaatcgt ggaaataaat atacctttga actggctcaa agtttctcaa
    12241 aagagtattc aggtggcgaa aaagtgtctt accccaatcc catagccata cctatcaatg
    12301 ggggctggcg atacaactat ggcaatatgt tttatgtgca actggtaacg cagtatcttg
    12361 tcacaacaga gtttgatgat gatacggtac aagccatcat ggacgaagca ctgaaatatg
    12421 agggctggcg atacgtttac ggtggagctt ccccgactac ttcttttgat tgtagcggac
    12481 tgacacaatg gacgtatgga aaagctggaa ttaacttacc acgaaccgca caacagcaat
    12541 atgatgtgac ccagcatatc ccactatcgg aagcacaagc tggcgatttg gttttctttc
    12601 attctaccta taacgctggc tcttatatta ctcatgttgg gatatacctt ggcaataacc
    12661 gtatgtttca tgcaggcgac ccaatcggtt atgccgactt aacaagcccc tactggcaac
    12721 agcatttagt gggagcagga cgaatcaaac aatgagaaag gaagatttaa tgatgaaatt
    12781 tagaaaaaat cagaataaag aaaaacagat accaaaggaa aagaaacctc gtgtctataa
    12841 ggtcaatcct cataaaaagg ttgtgattgc cttgtgggta cttttagggc ttagtttcag
    12901 ctttgcgata ttcaagcact ttacagctat agatactcat actattcacg aaacaactat
    12961 catagaaaag gaatacgttg atactcatca tgtagaaaat tttgtagaga actttgcgaa
    13021 agtctactat tcatgggagc aatccgataa gtccattgat aatcgaatgg aaagtctaaa
    13081 aggctatctg acagatgaac ttcaagctct caatgttgat acagtacgca aagatattcc
    13141 tgtatcgtct tctgtaagag gatttcagat atggacggta gagccaactg gcgacaatga
    13201 gtttaatgta acctacagtg tagaccagct cattacagag ggagaaaata caaagaccgt
    13261 ccactctgct tatatagtga gtgtctatgt agatggttct ggaaatatgg tactggttaa
    13321 gaatccgacc attaccaaca tacctaagaa atcaagttat aaaccaaaag ccattgaaag
    13381 tgaggggacg gttgattcca ttacaaccaa tgaaatcaat gagtttttaa cgacgttctt
    13441 caagctctat cctacagcga cagccagtga actttcctac tatgtgaatg acgggatatt
    13501 aaaaccaatc ggaaaagagt acatctttca agaactggta aatcctattc acaatcgtaa
    13561 ggataatcaa gtcacggtat cgctgacagt ggagtatatc gaccagcaga ccaaagcaac
    13621 gcaggtatct caatttgatt tggtacttga aaagaacggg agtaattgga agattataga
    13681 ataacaaata ttggtacatt attacagcta ttttgtaatc acgtactctc tttgataaaa
    13741 aattggagat tcctttacaa atatgctctt acgtgctatt atttaagtat ctatttaaaa
    13801 ggagttaata aatatgcggc aaggtattct taaataaact gtcaatttga tagtgggaac
    13861 aaataattgg atgtcctttt ttaggagggc ttagtttttt gtacccagtt taagaatacc
    13921 tttatcatgt gattctaaag tatccggaga atatctgtat gctttgtatg cctatggtta
    13981 tgcataaaaa tcccagtgat aaaagtattt atcactggga tttttatgcc cttttgggtt
    14041 tttgaatgga ggaaaatcac atgaaaatta ttaatattgg agttttagct catgttgatg
    14101 caggaaaaac taccttaaca gaaagcttat tatataacag tggagcgatt acagaattag
    14161 gaagcgtgga caaaggtaca acgaggacgg ataatacgct tttagaacgt cagagaggaa
    14221 ttacaattca gacaggaata acctcttttc agtgggaaaa tacgaaggtg aacatcatag
    14281 acacgccagg acatatggat ttcttagcag aagtatatcg ttcattatca gttttagatg
    14341 gggcaattct actgatttct gcaaaagatg gcgtacaagc acaaactcgt atattatttc
    14401 atgcacttag gaaaatgggg attcccacaa tcttttttat caataagatt gaccaaaatg
    14461 gaattgattt atcaacggtt tatcaggata ttaaagagaa actttctgcc gaaattgtaa
    14521 tcaaacagaa ggtagaactg tatcctaata tgtgtgtgac gaactttacc gaatctgaac
    14581 aatgggatac ggtaatagag ggaaacgatt accttttaga gaaatatatg tccggtaaat
    14641 cattagaagc attggaactc gaacaagagg aaagcataag atttcagaat tgttctctgt
    14701 tccctcttta tcatggaagt gcaaaaagta atatagggat tgataacctt atagaagtta
    14761 ttactaataa attttattca tcaacacatc gaggtccgtc tgaactttgc ggaaatgttt
    14821 tcaaaattga atatacaaaa aaaagacaac gtcttgcata tatacgcctt tatagtggag
    14881 tactacattt acgagattcg gttagagtat cagaaaaaga aaaaataaaa gttacagaaa
    14941 tgtatacttc aataaatggt gaattatgta agattgatag agcttattct ggagaaattg
    15001 ttattttgca aaatgagttt ttgaagttaa atagtgttct tggagataca aaactattgc
    15061 cacagagaaa aaagattgaa aatccgcacc ctctactaca aacaactgtt gaaccgagta
    15121 aacctgaaca gagagaaatg ttgcttgatg cccttttgga aatctcagat agtgatccgc
    15181 ttctacgata ttacgtggat tctacgacac atgaaattat actttctttc ttagggaaag
    15241 tacaaatgga agtgattagt gcactgttgc aagaaaagta tcatgtggag atagaactaa
    15301 aagagcctac agtcatttat atggagagac cgttaaaaaa tgcagaatat accattcaca
    15361 tcgaagtgcc gccaaatcct ttctgggctt ccattggttt atctgtatca ccgcttccgt
    15421 tgggaagtgg aatgcagtat gagagctcgg tttctcttgg atacttaaat caatcgtttc
    15481 aaaatgcagt tatggagggg atacgctatg gctgtgaaca aggattgtat ggttggaatg
    15541 tgacggactg taaaatctgt tttaagtatg gcttatacta tagccctgtt agtaccccag
    15601 cagattttcg gatgcttgct cctattgtat tggaacaagt cttaaaaaaa gctggaacag
    15661 aattgttaga gccatatctt agttttaaaa tttatgcgcc acaggaatat ctttcacgag
    15721 catacaacga tgctcctaaa tattgtgcga acatcgtaga cactcaattg aaaaataatg
    15781 aggtcattct tagtggagaa atccctgctc ggtgtattca agaatatcgt agtgatttaa
    15841 ctttctttac aaatggacgt agtgtttgtt taacagagtt aaaagggtac catgttacta
    15901 ccggtgaacc tgtttgccag ccccgtcgtc caaatagtcg gatagataaa gtacgatata
    15961 tgttcaataa aataacttag tgtattttat gttgttatat aaatatggtt tcttgttaaa
    16021 taagatgaaa tattttttaa taaagatttg aattaaagtg taaaggagga gatagttatt
    16081 ataaactaca agtggatatt gtgtcctgta tgtggaaata aaacacgatt aaagataagg
    16141 gaagatactg aattaaaaaa attccccctc tattgtccga aatgcagaca agaaaattta
    16201 attgaaataa agcagttcaa agtaactgtg attacagagc cagacgcaaa gacgcagagc
    16261 cgataaaatg agattaatac aatctcattt tatcggctct ttccgttatg tatggattct
    16321 tttaattagt cttcgatgtt tcttgcttcg ttgataccgc tggctaaaga ttccattaag
    16381 gatagttctt tgtctgtaaa gctatccatg tatttctcta tctgtaatcg tcgggtgctt
    16441 tttaccaagt tattagcagg taagaaaaat tcatcaacgg aaacatgaag taacgataca
    16501 aggtcataaa gaacttgtat gctggggtgt tgccctttat tttcaatatt agttaagtac
    16561 cgtgggtcaa tttcaatcaa tgctcccact tgttcacgag ttaaacctcg tttcaatcga
    16621 gcttctttaa tggctaaacc aaaggctcta aaatcatatt tatcttcttt tttacgcata
    16681 gtagaccacc tctatacatt ttattgttcc tactgaatta aaaacaggta tagaaaaacg
    16741 tgttatatgg tttataggtt tatatttaat aaaaagcact actaaacgcc aataaaaaaa
    16801 accgttatat ggtagtgcta tttacgctgt taaaatattg tatattactt ccaaatggcg
    16861 gtttgttgga ggtcaacgtc gccatgaagt acatcatata caataaattt ccttacattg
    16921 ggttcttgtc aaaaaaagtc gtctatctgc aatagataag tacgtccacc aatgtggttt
    16981 tataaatcat atagatagaa taacagaagc atgtaaacag agaaataaat ctgtttatat
    17041 gcttttttgg ctattcagaa cttttttaca aagtttattt atcagtaatg caacaaatcc
    17101 ccctttcaca ttgggactaa gag
//
